Momwe mungatenge metformin

Mankhwala a hypoglycemic Metformin ali ndi metformin, chinthu chopanga chomwe ndi chachikulu. Zowonetsa mwachindunji za mankhwalawa zimawonetsa chithandizo / prophylaxis ya mtundu II matenda a shuga. Kuchita, mankhwalawa amagwiritsidwa ntchito pazinthu zonse zomwe zimatsatana ndi hyperglycemia, ndipo mavuto, omwe mwina amaphatikizidwa ndi kusokonezeka kwa metabolic ndi / kapena kuchuluka kwa glucose kuposa kwazonse. Mankhwalawa amaphatikizidwa ndi mankhwala ophatikizira a polycystic ovary, kusinthanso kwachulukidwe, kunenepa kwambiri, ziphuphu, mtundu wa matenda a shuga.

Metformin imapangidwa m'mitundu iwiri:

• Mapiritsi okhala ndi mawonekedwe a metformin wamba,
• mapiritsi olimbitsa amasulidwe (akuchedwa kutulutsidwa kwa metformine).

Dyspepsia kapena mavuto ena amapezeka m'milungu yoyamba ya 1-2 yamankhwala. Popewa mawonetsedwe awo, mankhwala omwe ali ndi metformin amatengedwa ndi chakudya. Kukonza kotsika koyamba kwa shuga kuyenera kuyambitsidwa molondola ndi mlingo wochepa wa 500-850 mg / tsiku. Ndiye sabata iliyonse kuchuluka kwa mankhwalawa kumawonjezeka. Sizoletsedwa kudya kuposa 3 ga metformin patsiku.

Nthawi yanji tsiku la kumwa Metformin - zimatengera mtundu wamankhwala. Malinga ndi muyezo, mankhwala omasulidwa nthawi yayitali amamwa mankhwalawa, ndipo mapiritsi okhala ndi chiwonetsero chabwinobwino - masana. Koma thupi la munthu aliyense limagwirira mosiyana ndi metformin, kotero endocrinologist nthawi yamankhwala imatha kupatsanso mitundu ina yogwiritsira ntchito.

Kutulutsidwa pafupipafupi Mapiritsi

Metformin yachizolowezi chochita chimapezeka m'mapiritsi osavomerezeka kapena filimu kapena enteric. Anthu odwala matenda a shuga amatha kutumizidwa kumwa katatu patsiku, nthawi zonse nthawi yomweyo monga chakudya. Mlingo umatengera kusala kudya komanso mutatha kudya, kaya wodwala akutenga mankhwala ena a hypoglycemic.

Mitundu yodziwika ya Metformin monotherapy yokhala ndi nyengo yodziwika yotulutsira:

• 500 mg kapena 850 mg metformine / nthawi 1 m'mawa (ndikusala kudya kwa hyperglycemia, prediabetes),
• 500-850 mg 1 nthawi / nkhomaliro (chifukwa cha kuchuluka kwa shuga mkati mwa tsiku),
• 500-850 mg pa chakudya cham'mawa komanso chamadzulo (ndi shuga pang'ono),
• 850-1000 mg 2 p./day (m'mawa / madzulo ndi kuchuluka kwamphamvu kwa shuga),
• 850 mg katatu / tsiku (lokhala ndi hyperglycemia yokhala ndi gawo loyamba la kunenepa kwambiri),
• 1000 mg 3 p./day (odwala matenda ashuga onenepa kwambiri),
• 500-850 mg / 1 nthawi iliyonse patsiku (pazinthu zosagwirizana ndi shuga),
• 500-1000 mg metformine 1-3 p./day (yogwiritsidwa ntchito ndi kuchepa kwa thupi ngati palibe matenda a shuga).

Ngati munthu adayikidwa mankhwala angapo a hypoglycemic kapena insulin, Metformin imayenera kumwa m'mawa kapena usiku ndi kumwa pang'ono. Kuchulukana kwa metformine tsiku ndi tsiku nthawi zambiri kumapitirira 850 mg.

Mapiritsi okhala ndi nthawi yayitali

Mankhwala ochepetsedwa pang'onopang'ono amatulutsidwa m'mapiritsi osavomerezeka kapena povala filimu. Amasonyezedwa kumwa metformin yayitali tsiku lililonse usiku. Mankhwalawa amamwetsedwa nthawi ndi chakudya chamadzulo kapena atamaliza. Ngati, malinga ndi chiwembuchi, kuchuluka kwa glucose sikungatheke, dokotala amalimbikitsa kudya kawiri pa tsiku.

Malangizo a monotherapy ndi Metformin Long malinga ndi malangizo:

• Mlingo umodzi mu milungu iwiri yoyambirira ya mankhwala ndi 500-850 mg 1 nthawi / madzulo.
• Mu sabata lachitatu kuyambira pakuyamba kwa mlingo, muyeso uyenera kuchuluka mpaka 850-1700 mg (malingana ndi zowonetsa komanso pakakhala zovuta zina).
• Pakumapeto milungu 4, mankhwalawa amayenera kumwa pa mlingo woyenera wa endocrinologist.

Patatha mwezi umodzi, osagwirizana ndi kuyendetsa bwino shuga, wodwalayo amatha kupitiliza kumwa mankhwala kwa nthawi yayitali. Pankhaniyi, akuwonetsedwa kumwa Metformin m'mawa ndi madzulo: 1/2 ya mankhwala othandizira tsiku ndi tsiku, limodzi ndi kadzutsa ndi chakudya chamadzulo. Pambuyo pa masabata 1.5-2, endocrinologist imawunika mtundu wa shuga. Ngati kuchuluka kwa shuga sikungokhala kosasunthika, wodwalayo amawabwezera kuti akalandire chithandizo ndi mapiritsi pamlingo wanthawi zonse.

Zindikirani

Ndi chithandizo chovuta ndi mapiritsi a Metformin, ndizotheka kupereka mankhwala ophatikizika m'malo mwa othandizira angapo a hypoglycemic. Mankhwala oterowo, metformin imaphatikizidwa ndi vildagliptin, glibenclamide, glyclazide, glimepiride, rosiglitazone kapena sitagliptin. Mankhwala okhala ndi magawo awiri amagwiritsidwanso ntchito molingana ndi ziwembu: m'mawa / madzulo, chakudya cham'mawa / nkhomaliro / chakudya chamadzulo, 1 nthawi / tsiku (pamimba yopanda kanthu, masana kapena usiku). Phwando limafotokozedwa mwatsatanetsatane mwatsatanetsatane.

Vidal: https://www.vidal.ru/d drug/metformin-5
Radar: https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGu>

Mwapeza cholakwika? Sankhani ndikusindikiza Ctrl + Lowani

Momwe mungamwe Metformin usiku: kumwa mankhwalawa?

Ambiri ali ndi chidwi ndi momwe angatenge Metformin kuti akwaniritse zabwino zowerengera.

Kuti muyankhe funsoli, muyenera kuphunzira momwe mungagwiritsire ntchito mankhwalawo mwatsatanetsatane ndikupeza malangizo kuchokera kwa endocrinologist.

Mankhwalawa amapezeka mu mawonekedwe a mapiritsi, omwe ali amitundu itatu kutengera mlingo: 500, 850 ndi 1000 mg. Chofunikira kwambiri chomwe chili mu mankhwalawo ndi metformin. Omwe amapangidwa ndi mankhwalawa ndi magnesium stearate, crospovidone, povidone K90, talc, wowuma chimanga.

Metformin, kapena metformin hydrochloride ndi woimira kalasi yayikulu, yomwe imathandizira kuthetsa hyperglycemia, ndiko kuti, kuwonjezeka kwa shuga m'magazi. Mankhwala oterewa amatengedwa makamaka ndi mtundu wachiwiri wa matenda ashuga. Mwambiri, wodwala yemwe amamwa mankhwalawa adzapulumutsidwa pazizindikiro za hypoglycemia, chifukwa njira zotsatirazi zizichitika mthupi:

1. Kuchulukitsidwa kwa glucose ndi zotumphukira zimakhala.
2. Kuchepetsa njira yogawa mafuta ndi mapuloteni.
3. Mofulumira kaphatikizidwe wa shuga m'magawo am'mimba ndikusintha kwake kukhala lactic acid.
4. Kuletsa kumasulidwa kwa glycogen ku chiwindi.
5. Kuthetsa insulin kukana.
6. Kukondoweza kwa kuchuluka kwa shuga m'chiwindi.
7. Kupereka cholesterol, komwe kumakomera boma la lipids.

Metformin ilibe gawo lililonse pakugwira ntchito kwa kapamba, yemwe amapanga insulin. Mankhwala sangayambitse hypoglycemia - kuchepa kwa kuchuluka kwa shuga m'magazi.

Malangizo ogwiritsira ntchito mankhwalawa

Musanagwiritse ntchito Metformin, muyenera kudziwa zomwe amagwiritsa ntchito.

Pankhaniyi, ndikwabwino kutsatira malingaliro a dokotala yemwe amapereka mankhwala, poganizira zomwe wodwala aliyense ali nazo.

Zizindikiro zodziwika ngati mankhwalawa ndi:

• lembani 1 ndi matenda ashuga 2
• prediabetes (mkhalapakati),
• kunenepa kwambiri ndi kuvutitsidwa kwa insulin,
• matenda acopolycystic ovary,
• kagayidwe kachakudya matenda
• pamasewera
• kupewa kukalamba.

Ngakhale pali mndandanda wazambiri zamankhwala omwe mungamwe Metformin, nthawi zambiri amatengedwa ndi matenda a shuga a 2. Mu mtundu woyamba wamatenda, mankhwalawa amagwiritsidwa ntchito kwambiri kawirikawiri, makamaka ngati cholumikizira insulin.

Kafukufuku ambiri adawonetsa kuti ngakhale kumwa mankhwalawa nthawi imodzi ndi jakisoni wa insulin, kufunika kwa mahomoni kumachepa pafupifupi 25-50%. Kuphatikiza apo, atatha kugwiritsa ntchito mankhwalawa kwa nthawi yayitali, kubwezeretsedwa kwa kagayidwe kazakudya kumatha bwino. Amagwiritsidwanso ntchito mumtundu wachiwiri wa shuga, womwe umafuna jakisoni wa insulin.

Mtundu wachiwiri wa matenda, Metformin amalembedwa pafupifupi pafupifupi chilichonse. Pa monotherapy, mlingo uyenera kuwonjezeka pang'onopang'ono. Chifukwa chake, poyamba amaloledwa kugwiritsa ntchito piritsi limodzi patsiku (500 kapena 850 mg). Ndikofunika kumwa mankhwalawa madzulo, koma kupewa chisokonezo cha m'mimba, ndikofunikira kuti mumwe mapiritsi mukamadya chakudya kawiri patsiku - m'mawa ndi madzulo.

Popita nthawi, mlingo wa mankhwalawa ukhoza kuwonjezereka mwa kufunsa dokotala musanatero.Mlingo waukulu patsiku suyenera kupitilira 2,5 mg, ndiye kuti, wodwalayo amatha kumwa mapiritsi atatu patsiku. Pakatha milungu iwiri, kagayidwe kazakudya umayamba kubwerera mwakale. Pambuyo pakufika pamlingo wabwinobwino wamagazi, mulingo umatha kuchepetsedwa.

Kuphatikizidwa kwa mankhwalawa Metformin ndi sulfonylurea kumatha kubereka kwakanthawi kochepa. Koma thupi la munthu limazolowera kwambiri mankhwala amtunduwu. Chifukwa chake, monotherapy yokhala ndi Metformin imatha kukhala ndi tanthauzo lokhalitsa. Komabe, mu 66% ya odwala matenda ashuga, kuphatikiza kwa mankhwalawa kumapangitsanso kagayidwe kazachilengedwe.

Metformin imasungidwa pamtunda wosaposa 25 ° C kutali ndi ana. Alumali moyo wa mankhwala 3 zaka.

Contraindication ndi zoyipa

Musanayambe kumwa mankhwalawa, muyenera kuonetsetsa kuti angathe kumwa ndi wodwala. Monga mankhwala ena, Metformin ili ndi zotsutsana, monga:

• nthawi yobala mwana,
• yoyamwitsa
• ana ochepera zaka 10,
• uchidakwa wambiri,
• matenda a impso, chiwindi, mtima ndi kupuma dongosolo,
• matenda a shuga kapena kholo,
• m'mbuyomu lactic acidosis kapena kudziwiratu kwake,
• Zakudya zochepa zopatsa mphamvu
• kuvulala kwam'mbuyomu komanso kulowererapo kwakukulu.

Ziyenera kuyang'ana pang'ono pa lactic acidosis - kudzikundikira kwa lactic acid. Zinthu zina zimatha kubweretsa kukulira kapena kufalikira kwa lactic acidosis:

1. Zotsatira zake, kuwonongeka kwa impso, chifukwa, kulephera kuchotsa acid,
2. kuledzera kwa ethanol chifukwa cha uchidakwa wambiri,
3. kulephera kwa mtima ndi kupuma,
4. Matenda oletsa kupweteka m'mapapo,
5. matenda opatsirana omwe amachepetsa thupi - kusanza, kutsegula m'mimba, kutentha thupi,
6. matenda ashuga ketoacidosis (kuphwanya chakudya cha metabolism),
7. myocardial infaration.

Mankhwala osokoneza bongo omwe amapezeka molakwika amatha kuyambitsa zovuta zingapo kwa wodwala, mwachitsanzo:

• kugaya chakudya m'mimba - kusanza, kusanza, kutsegula m'mimba, kutsekemera kwazitsulo, kuchepa kapena kusowa kudya kwathunthu,
• thupi lawo siligwirizana - zotupa pakhungu ndi kuyabwa,
• lactic acid chikomaso ndichosowa, koma nthawi yomweyo zovuta zowopsa.

Kwenikweni, zovuta zoyipa zimangokhala zokha pakatha milungu iwiri atamwa mankhwalawo. Izi ndichifukwa choti mankhwalawa amalepheretsa kuyamwa kwa shuga m'matumbo. Zotsatira zake, chakudya chimayamba kuthiramo, zimayambitsa bata, kenako zizindikiro zina zosokoneza m'mimba. Nthawi zambiri thupi limazolowera zochita za mankhwalawa, ndipo ngati zovuta zina sizovuta kupirira, ndiye kuti palibe chithandizo chamankhwala chomwe chikuyenera kuchitika.

Asanatenge Metformin, wodwalayo ayenera kufotokozera zonse zomwe zidakhalapo ndipo zilipo, popeza kubisika kwa chidziwitso chofunikira chotere kukhoza kuvulaza wodwala.

Kugwiritsa ntchito mankhwalawa kunenepa kwambiri

Anthu ambiri odwala matenda ashuga omwe ali ndi mtundu wachiwiri wa matenda ndi onenepa kwambiri kapena onenepa kwambiri.

Zikatero, kugwiritsa ntchito mankhwalawa Metformin kungakhale ndi zotsatira zabwino pakuchepetsa thupi kwa wodwala. Koma pofuna kuvulaza thupi lake, wodwala matenda ashuga ayenera kutsatira izi:

1. Njira ya mankhwala sayenera kupitirira masiku 22.
2. Kumwa mapiritsi, wodwalayo ayenera kukhala ndi moyo wokangalika.
3. Kumwa mankhwalawo kumayenderana ndi kumwa kwambiri.
4. Mankhwalawa amalepheretsa wodwala kudya.

Tsiku lililonse, wodwala matenda ashuga ayenera kuchita zinthu zina zolimbitsa thupi, kaya kuthamanga, kukwera maulendo, kusambira, volleyball, mpira wachinyamata ndi zina zambiri. Kuchokera muzakudya muyenera kupatula zopaka zophika mkate, makeke, chokoleti, kupanikizana, uchi, zipatso zotsekemera, zakudya zamafuta ndi zokazinga.

Dokotalayo amadzidalira payekha mlingo wa mankhwalawo. Sizingatheke kuti muzingochita nokha mankhwala chifukwa izi zimabweretsa zotsatirapo zoyipa.Itha kugwiritsidwanso ntchito ndi anthu omwe onenepa kwambiri, koma amakonda kuzala.

Nthawi zambiri, kuchuluka kwa mankhwalawa kwa iwo kumacheperachepera.

Mtengo ndi fanizo la mankhwala

Mankhwalawa atha kugulidwa ku pharmacy iliyonse mumzinda kapena kuyitanidwa pa intaneti. Popeza Metformin imapangidwa ndi makampani osiyanasiyana apakhomo ndi akunja, mtengo wake umatha kusiyanasiyana.

Mwachitsanzo, ngati wopanga mankhwalawo ndi kampani yaku Russia, ndiye kuti mtengo wake, kutengera mlingo, ungakhale wa ma ruble 112 mpaka 305. Ngati wopangayo ali ku Poland, ndiye kuti mtengo wa mankhwalawo ku gawo la Russian Federation umachokera ku 140 mpaka 324 rubles. Mankhwalawa ndi ochokera ku Hungary m'dera la Russian Federation kuyambira 165 mpaka 345 ma ruble, kutengera kuchuluka kwa zinthu zomwe zikugwiritsidwa ntchito.

Mtengo wa mankhwalawo ndiolandilidwa kwa anthu omwe ali ndi ndalama zapakati komanso zochepa. Chifukwa chake, mankhwalawa amatha kusankhidwa potengera zochizira zomwe zikuyembekezeredwa komanso kuthekera kwachuma kwa ogula. Chifukwa chake, simungagwiritse ntchito mankhwala okwera mtengo omwe amakhala ndi zotsatira zofanana ndi zotsika mtengo.

Popeza mankhwalawa amapangidwa m'maiko ambiri, amatha kukhala ndi ma synonyms ambiri, mwachitsanzo, Gliformin, Metfogamma, Bagomet, Formlinpliva ndi zina. Palinso mankhwala ena ofanana omwe amatha kumwa ngati Metformin pazifukwa zina sioyenera kuthandizira wodwala. Izi zikuphatikiza:

• Glucophage ndi mankhwala othandiza mankhwalawa matenda a shuga 2 komanso kunenepa kwambiri. Ili ndi katundu wa hypoglycemic. Kafukufukuyu akuwonetsa kuti kumwa mankhwalawa kumachepetsa kufa kwa anthu odwala matenda ashuga ndi 53%, kulowetsedwa myocardial - ndi 35%, stroke - ndi 39%. Mtengo wapakati (500 mg) ndi 166 ma ruble.
• Siofor ndi mankhwala ena abwino ochepetsa shuga m'magazi. Zake ndikuti mankhwalawa akhoza kuphatikizidwa ndi sulfonylurea kukonzekera, salicylates, insulin ndi ena. Chithandizo chokwanira chimasintha zotsatira zomwe zikuyembekezeka. Mtengo wapakati (500 mg) ndi ma ruble 253.

Odwala ambiri amadabwa kuti ndi mankhwala ati omwe amaposa. M'malo mwake, mankhwala ambiri amakhala ndi chinthu chogwira - metformin, kusiyana kumangokhala pazinthu zothandizira, chifukwa ali ndi zotsatira zofanananso ndi matenda a shuga.

Ndemanga za Odwala za Metformin

Ndemanga za kugwiritsa ntchito mankhwala a Metformin nthawi zambiri ndi zabwino.

Odwala ambiri omwe ali ndi matenda a shuga a 2 amawona kuchepa kwamphamvu kwa glucose kutsika mwazomwezo ndikuwasunga pamlingo womwewo.

Kuphatikiza apo, zabwino za chida ichi ndi:

• mawonekedwe abwino a mapiritsi omwe ayenera kumeza ndi kutsukidwa ndi madzi,
• ntchito imachitika kamodzi kapena m'mawa ndi madzulo,
• m'malo otsika mtengo wa mankhwalawo.

Makasitomala ambiri adanenanso kuchepa thupi pamene akutenga Metformin. Koma nthawi yomweyo, muyenera kutsatira malamulo angapo: kusewera masewera, kutsatira zakudya, kumwa zamadzi zambiri, kudziletsa pakudya. Kuti muchite izi, muyenera kudya zipatso ndi ndiwo zamasamba, zakudya zopatsa mphamvu, zakudya zamafuta ambiri.

Nthawi zina mutha kupeza ndemanga zoyipa za odwala za mankhwalawa. Amaphatikizidwa makamaka ndi zotsatira zoyipa za mankhwalawa. Monga tanena kale, mavuto ambiri amachoka pawokha patatha milungu iwiri atalandira chithandizo, chifukwa thupi limazolowera zochita za metformin.

Metformin ndi mankhwala abwino kwambiri omwe amagwiritsidwa ntchito kuchepetsa matenda a shuga mu mtundu woyamba wa 2 komanso wa shuga. Amagwiritsidwa ntchito ngati chowonjezera cha mankhwala a insulin, komanso monga mankhwala othandizira shuga ochulukitsa mu mtundu wachiwiri wa matenda. Musanagwiritse ntchito mankhwala, kufunsira kwa dokotala ndikofunikira, komwe kungayang'ane zolakwika zonse ndikupereka mankhwala olondola.

Kuphatikiza apo, Metformin siyogulitsa popanda mankhwala.M'malo mwake, zotsutsana ndi zovuta za mankhwalawa ndizochepa, ndipo mawonekedwe ake ndi osowa kwambiri. Mwambiri, ndemanga za mankhwalawa ndi zabwino. Chifukwa chake, mankhwalawa amatha kuonedwa ngati osavulaza komanso othandiza.

Mulimonsemo, kugwiritsa ntchito mankhwala osokoneza bongo kuyenera kumayendera limodzi ndikuwunika kuchuluka kwa shuga pogwiritsa ntchito glucometer, zolimbitsa thupi komanso kupatula zakudya zamafuta ndi yokazinga, makeke, maswiti a zakudya. Pokhapokha kutsatira malamulo onsewa, wodwalayo amatha kukwaniritsa zotsatira zazitali za mankhwalawo ndikusunga kuchuluka kwa shuga m'magazi osiyanasiyana.

Malamulo ogwiritsa ntchito Metformin adzakambidwa mu kanema munkhaniyi.

Sonyezani shuga yanu kapena sankhani jenda kuti muyimikize.

Momwe mungatenge metformin?

Metformin ndi mankhwala othandizira odwala matenda a shuga omwe amaperekedwa mwanjira yoyera ya mapiritsi a biconvex yoyera yophimbidwa ndi enteric. Anawonekera pamsika wamankhwala mu 1957 ndipo mpaka lero ndi mtsogoleri wodziwika pantchito ya mankhwala a hypoglycemic.

Chizindikiro chogwiritsidwa ntchito ndi mtundu II matenda a shuga, kuphatikiza komanso kutsimikizika kosakwanira kwa magulu a sulfonylurea. Kuphatikiza apo, metformin canon imapangidwira kunenepa kwambiri komanso zovuta zomwe zimachitika pakudya.

MH - Metformin. INN ili ndi dzina lapadera la mankhwala omwe amaperekedwa. Mankhwalawa ali ndi vuto la hypoglycemic, amapangidwira pakamwa ndipo ndi a gulu la Biguanides. Alumali moyo wa mankhwalawa ndi zaka zitatu, uyenera kusungidwa m'malo otetezedwa kuchokera ku kuwala komanso kuchokera kwa ana pamtunda wa 15-25C. Amapezeka mu 500 mg, 850 mg ndi 1000 mg. Mankhwala amapezeka ndi mankhwala.

Metformin ndi Type IIabetes

Chizindikiro cha kuperewera kwa mankhwalawa ndi mtundu II matenda osokoneza bongo osagwira ntchito zolimbitsa thupi komanso kugwiritsa ntchito mankhwala othandizira. Kuphatikiza apo, monotherapy imatha kuchitika ndi mankhwalawa kapena kuthandizira pamodzi ndi mapiritsi ena amkamwa a hypoglycemic.

Nthawi zambiri, ngati tili ndi matenda a shuga a mtundu wachiŵiri, timayambitsa matenda a metabolic (ma syonyms - syndrome x, insulin-insulin). Lingaliro lotakata limalumikizidwa ndi kuphwanya kwamachitidwe a kuthamanga kwa magazi, komwe kumakhazikitsidwa pakuchepa kwa chidwi cha zolandilira maselo ku insulini, komanso kuchepa kwamafuta ndi chakudya cha carbohydrate. Matendawa ndi asymptomatic, koma patadutsa zaka zingapo matendawa atayamba, zovuta za matenda a mtima, matenda a mtima, etc. zimayamba kuonekera. Pofuna kupewa izi, ntchito zimakhazikitsidwa zomwe cholinga chake chachikulu ndikusintha moyo ndikuchepetsa thupi. Popeza kuti ndi ochepa odwala omwe amakhala ndi moyo wathanzi ndipo amatsatira malamulo onse a dotolo, mankhwala amalembedwa chifukwa chaichi. Pankhaniyi, ndi Metformin Canon, yomwe ili ndi njira yolimbikitsira kuchitapo kanthu ndikuthandizira kuchepetsa thupi komanso kubwezeretsa chidwi cha ma cell receptors.

Kuchiza ndi Metformin Canon kapena mawonekedwe ake Siofor, Glyukofazh, Maniil, ndi ena. Kukuwonetsedwanso motsutsana ndi chizindikiro cha ovary syndrome (PCOS). Kupezeka kwa PCOS kumatha kupangitsa kukhalapo kwa matenda ashuga a 2. Pankhaniyi, thupi limavulazidwa osati ndi kukhalapo kwa matenda a shuga a 2, komanso PCOS. Kukonzanso kwa ma follicles a ovary kumayambitsa mapangidwe a zipsera pazinthu za ziwalo ndi kuwonongeka kwa magwiridwe antchito. Chifukwa cha izi, amasiya kupanga ma mahomoni moyenera, ndipo thupi limapitilizabe kupanga insulini, yomwe imalimbikitsa mazira kuti apange testosterone.Njira yamtunduwu yokhudza thupi imathandizira ndikuvulaza thanzi. Pali kuchuluka kwa testosterone kwakukulu, komwe kumayipa magwiridwe antchito am'mimba ndikumakhudza ntchito yobereka. PCOS ndiyomwe imayambitsa matenda ambiri komanso zovuta.

Zizindikiro zogwiritsidwa ntchito

Madokotala amapereka metformin pazochitika zotsatirazi:

• lembani matenda ashuga a 2 osawerengeka popanda chizolowezi cha keacidosis,
• carbohydrate kagayidwe kachakudya mu akazi mu udindo (gestational shuga),
• polycystic ovary syndrome,
• kupewa matenda pafupi ndi matenda ashuga.

Pakadali pano, ofufuza achilendo, atapanga zoyeserera zingapo, akuti kutenga metformin kumachepetsa chiopsezo cha zotupa zoyipa zomwe zimachitika m'matenda a shuga. Chifukwa chake, mankhwalawa nthawi zambiri amapatsidwa mankhwala opewera.

Njira yamachitidwe

Kuchiza ndi wothandizira kumachepetsa kupanga shuga ndi chiwindi, komwe kumakhudza kuchepa kwa kudya kwa hyperglycemia. Tizilombo toyambitsa matenda tosiyanasiyana ndi kuchepa kwa makutidwe amtundu wa lipids ndi mafuta aulere acids, komanso kuponderezana kwa gluconeogenesis kuchokera ku lactate.

Ngati mumwa mankhwalawa malinga ndi chiwembu, mutha kuwona kuwongolera kwakukulu kwamafuta a metabolism mwa anthu omwe ali ndi vuto la glucose. Zimawonjezera kukhudzika kwa maselo kuti apange insulini ndipo amalimbitsa kulumikizana kwake ndi ma receptor mu hepatocytes, adipocytes, erythrocyte, ndi zina, potero, kukulitsa kuchuluka kwa shuga ndikugawa pamisempha.

Kuphatikiza apo, mankhwalawa amathandizira kuchepetsa kubwezeretsanso kwa matumbo m'matumbo, omwe amatha kuthothoka momveka bwino m'matumbo a glycemic mukatha kudya.

Mlingo ndi njira ya mankhwala

Kutengera ndi kuchuluka kwa shuga m'magazi a wodwalayo, adotolo amafotokozera mlingo woyenera. Kumayambiriro kwa mankhwalawa, mlingo umatha kuchoka pa 500-1000 mg patsiku ndipo pang'ono ndi pang'ono umawonjezeka pambuyo pa masabata awiri molingana ndi kuchuluka kwa shuga. Kuti mukhale ndi thanzi labwinobwino, ndikofunika kumwa mapiritsi 3-4 patsiku (1500-2000 mg). Mlingo wovomerezeka wokwanira kuchokera ku 1000 mpaka 3000 mg.

Malangizo ogwiritsira ntchito metformin akuwonetsa kuti mankhwalawa amayenera kumwa nthawi yonse pachakudya kapena mukatha kudya, ndi kapu yamadzi opanda mafuta opanda mpweya. Pofuna kupewa zovuta kuchokera m'matumbo am'mimba, mlingo wa metformin wa tsiku ndi tsiku uyenera kugawidwa ndi 2-3, ndipo pakubwera kwa vuto la metabolic, mlingo umachepetsedwa.

Mu PCOS, chithandizo choyambirira ndi 500 mg patsiku kwa sabata limodzi. Kuphatikizanso, kuti musavulaze thanzi, ndibwino kuwonjezera mlingo pang'onopang'ono. Pakutha sabata yachiwiri ikhala 1000 mg. Mukazolowera komanso kutengera mtundu wa zolemetsa, muyezo wa kuchiritsira tsiku lililonse uzichokera ku 1000-3000 mg. Ngati metformin siili yoyenera kwa thupi, mutha kufunsa dokotala ndikusintha chithandizo ndi mawonekedwe ake, mwachitsanzo, siofor kapena manila.

Zotsatira zoyipa

Zakudya za mankhwala zilizonse zimawerengedwa payekhapayekha. Itha kukhala yoyenera kwa wina, ndikuyambitsa mavuto. Izi zitha kuchitika ngati mankhwala atagwiritsidwa ntchito mopitirira muyeso kapena osagwirizana ndi njira zochizira, pali chithunzi cha zotsatira zoyipa za metformin:

• kusanza, kusanza ndi mseru,
• kukomoka
• kupweteka kwam'mimba
• kulawa kwazitsulo mkamwa
• chisangalalo
• anemia yam'magazi,
• achina,
• kugona ndi kufooka
• hypotension
• dermatitis ndi zotupa pakhungu.

Metformin Canon

Kampani yaku Russia ya Canonfarm Production ipanga mankhwala otchedwa Metformin Canon. Mankhwalawa amakwaniritsa zonse zoyenera. Mapiritsiwo akupezeka mu Mlingo wa 500 mg, 850 mg ndi 1000 mg. Amalembera anthu odwala matenda ashuga a 2 mtundu. Mankhwalawa ali ndi vuto la hypoglycemic, amasintha mayamwidwe a insulin, komanso amachepetsa shuga.

Mlingo wake umasankhidwa ndi adotolo potengera momwe wodwalayo alili. Chithandizo, monga lamulo, chimayamba ndi zochepa. Mukamagwiritsidwa ntchito, mavuto obwera chifukwa cha mseru, kupweteka pamimba, komanso kusowa kwa chakudya kungachitike. Phatikizani ndi mankhwala ena mosamala chifukwa cha kupezeka kwa lactic acidosis.

Mtengo wa Metformin Canon uli mkati mwa ma ruble 200, kutengera mlingo wa mankhwalawo.

Metformin, analogues ndi kufananiza

Kugwiritsa ntchito bwino kwa mankhwalawa pathupi kumatsimikiziridwa ndi zomwe zimachokera, zomwe ndi zinthu zachilengedwe zomwe zimapezeka kuchokera kuzomera zotchedwa French lilac ndi muzu wa mbuzi. Odwala ambiri omwe ali ndi matenda ashuga, akulandila chithandizo ndi mapiritsi awa, ali ndi chidwi, ndipo ndimawu ofanana ati? Kodi pali kusiyana pakati pa mankhwalawa? Mitundu yofanana ndi iti ndi mankhwala ati omwe ndibwino kusankha? Chifukwa chake, pamafunso omwe aperekedwa, zonse zili mu dongosolo.

Metformin ili ndi ma fanizo odziwika kwambiri:

Kodi ndibwino, siofor kapena metformin? Siofor ndiopanga mankhwala ku Germany - BERLIN-CHEMIE. Siofor imapezeka mu mawonekedwe a piritsi ndipo imapangidwira kuti ikhale hypoglycemic ya mtundu II shuga mellitus. Siofor imawerengedwa ngati chithunzi chabwino cha metformin, chifukwa ilinso ndi mtengo wofanana wa pharmacokinetic.

Ndibwino, metformin kapena mannitol? Maninil ndiwothandiza kwambiri kuposa mankhwalawo. Zizindikiro ndi ma contraindication akufanana, manila alinso mankhwala a hypoglycemic a matenda a shuga II. Maninil amapezeka piritsi.

Ndibwino liti, glucophage kapena metformin? Glucophage ndi mankhwala osokoneza bongo a hypoglycemic. Ili ndi chiwonetsero chomwecho ndikugwiritsa ntchito kusiyana ndi metformin pokhapokha kuti glucophage imakhala 2 kupsinjika kwa ntchito ya m'mimba ndipo imakhala ndi mtundu wina wokhala ndi nthawi yayitali - Glukovazh-Long. Ndizofunika kudziwa kuti mtengo wa mankhwalawa Glucofage-Long, mosiyana ndi Metformin, umakhala wokwera mtengo kawiri.

Mankhwala onse omwe amaperekedwa Metformin, Glucofage, Siofor ndi Maniil ndi fanizo la cholinga ndi gulu la mankhwala. Zonsezi zili ndi zinthu zomwezo ndipo chifukwa chake sizosiyana. Zomwe zili bwino ndipo pali kusiyana kosankha kwa ogula okha.

Kugwirizana kwa mankhwala osokoneza bongo ndi mowa

Sikoyenera kunena kuti mowa wophatikiza uliwonse umangoyipa, komanso wopanda thupi. Mowa ndi metformin - chisakanizo osati chophulika chokha, komanso chowopsa m'moyo.

• Kumwa zakumwa zoledzeretsa ndi mankhwala ozikidwa pa metformin kumayambitsa kusokonezeka kwa metabolic komanso kupanga kwambiri lactic acid, zomwe zimapangitsa kuti pakhale matenda omwe amadziwika kuti lactic acidosis. Mlingo wa lactate umakwera kangapo. Vutoli limadziwoneka lokha ndi mseru wamphamvu komanso kusanza kokulirapo. Wodwalayo amadziwa zowawa kumbuyo kwa sternum ndi minofu, amakhala wopanda chidwi komanso mkhalidwe wa adynamia, kupuma kwamiseche ndikovuta, ndiye kuti akhoza kugwa. Pankhaniyi, muyenera kuyimbira ambulansi nthawi yomweyo, chifukwa Imfa ndiyotheka chifukwa cha kusokonezeka kwa magazi ziwalo, hypoxia ya ubongo komanso kulephera kwa mtima.
• Kugwiritsidwa ntchito kwa mowa ndi metformin kumachepetsa kuchuluka kwa vitamini B1. Izi zimalephera kulowa bwino m'mimba chifukwa cha mowa, zomwe zikutanthauza kuti thupi limasowa chofunikira nthawi zonse. Kuchuluka kwa vitamini kumeneku kumabweretsa kukula kwa lactic acidosis.
• Hypoxia la bongo. Vutoli limatha kuchitika chifukwa chakuwongolera kwa metformin komanso mowa. Izi zimapangitsa kuti pakhale kusowa kwa mpweya komanso kufinya kwamitsempha yamagazi.
• Pa matenda osiyanasiyana a impso, kugwiritsa ntchito mankhwala ndi mowa nthawi imodzi kumaletsedwa. Kuphatikizika kumeneku kumatha kuyambitsa zotsatirapo zoyipa zazikulu.
• Pamaso pa matenda a chiwindi, kuphatikiza uku kuyenera kutayikidwanso. Zowonongeka za kitiyi zimatha kuyambitsa kukomoka kwa hypoglycemic.

Wina anganene kuti ndibwino kupatula nthawi yomwera mowa ndi mankhwala, koma awa ndi malingaliro olakwika chabe. Pofuna kusakaniza metformin ndi mowa mthupi, muyenera kulumpha mapiritsi osachepera atatu. Izi ndizosavomerezeka kwa wodwala yemwe ali ndi matenda osokoneza bongo, chifukwa pamakhala chiwopsezo cha zovuta zina mwanjira ya ketoacidosis, hypo kapena hyperglycemic coma.

Ndemanga za madotolo za mankhwalawa

Ndemanga za madotolo pakugwiritsa ntchito mankhwalawa ngati kuchepetsa thupi ndikugwirizana kuti musanayambe kumwa metformin, muyenera kufunsa dokotala ndikuwerenga malangizo kuti mugwiritse ntchito bwino.

Ngati tilingalira nkhaniyi mwambiri, ndiye kuti mankhwalawa amatha kuwotcha mapaundi owonjezera ndikupangitsa kuti kagayidwe kake kaonekere. Kuchuluka kwa mankhwalawa chifukwa cha kuponderezana ndi chidwi cha chakudya, kuchuluka kwa mphamvu zamagalimoto, ndipo chifukwa chake, kutsika kwawo kumasintha kukhala mafuta, komanso kuchepa kwa shuga wamagazi.

Ndikotheka kutenga Metformin Canon, Maniil, Siofor, Glucofage kukonzekera ndi PCOS limodzi ndi zakudya. Mankhwala olimbana ndi kunenepa kwambiri amayenera kutsagana ndi malire a ufa, wokoma ndi wamafuta. Kupanda kutero, sizikupanga nzeru kumwa mankhwala osokoneza bongo ndikuwonjezera mphamvu pakhungu.

Komabe, kuwunika kwa madokotala kumadalira mgwirizano womwe:

1. Mlingo wovomerezeka wamankhwala sioposa 500 mg kwa anthu athanzi.
2. Kutalika kwa thupi pogwiritsa ntchito mankhwalawa sikuyenera kupitirira milungu itatu.
3. Gwiritsani ntchito metformin molondola komanso pokhapokha ngati mukuchita zolimbitsa thupi, ngati mukufuna kupeza zotsatira zochuluka chifukwa chomwa mapiritsi, apo ayi maphunzirowa sangawononge thupi ngati simuchita masewera.

Metformin yolimbana ndi ukalamba

Pali lingaliro lomwe metformin imathandizira kupititsa patsogolo unyamata komanso osakalamba. Kodi ndizomveka kukhulupirira kuti mapiritsi odana ndi ukalamba alipo? Inde, pali lingaliro kuti mukhulupirire, koma padziko lapansi palibe piritsi loletsa kukalamba kumwa ndipo nthawi yomweyo ali achichepere. Koma pali njira inanso yakukonzanso. Metformin, ngati yankho la matenda a shuga a mtundu 2, amadziwika kuti ndi njira yothandizira matenda okalamba. Mankhwalawa ali ndi zotsatirazi mthupi:

• Pali kuchepa kwa chiwerengero cha cholesterol plaque mu zombo. Zotsatira zake, kufalikira kwa magazi kumapangidwira, chiopsezo cha thrombosis chimachepetsedwa. Muna kuma kiaki, wantu awaya bekwikilanga yo kala ye kwikizi.
• Metabolism imakhala bwino. Munthu pang'onopang'ono amachepetsa thupi. Zotsatira zake, katundu pa machitidwe onse amthupi amachepa.
• Kulakalaka kumachepa, zomwe zimathandizanso kuchepetsa kunenepa.
• Glucose samatengeka kwambiri m'mimba. Chowonadi ndi chakuti shuga imathandizira kuphatikiza ma molekyulu a protein, ndipo izi ndizodzaza ndi ukalamba mwachangu.
• Kuchulukitsa kwa magazi. Zotsatira zake, chiwopsezo cha kuwundana magazi, kugunda kwa mtima, ndi mikwingwirima yafupika.

Chifukwa chake, mphamvu ya metformin m'thupi imakhala yopindulitsa ngati imagwiritsidwa ntchito moyenera. Zimathandizira kuchepetsa kukalamba.

Mukakalamba, metformin imachepetsa kufooka kwa munthu ndikutalikitsa moyo wake. Pankhaniyi, ndikosavuta kumvetsetsa tanthauzo la zomwe zili pamwambapa. Palibe mapiritsi olimbana ndi ukalamba, koma pali njira yochepitsira moyo wanu, kukonza mkhalidwe wa khungu, kupewa matenda, etc. Kupatula apo, palibe chabwino ngati munthu samangowoneka “watsopano”, komanso mawonekedwe a ziwalo zamkati ndi kayendetsedwe ka dongosolo.

Mwachidule, titha kunena kuti Metformin ndi fanizo lake Glyukofazh, Siofor, Maniil, etc. Mankhwala abwino kwambiri a mtundu wa 2 matenda a shugaNdikofunikira kuti mutsatire bwino malangizo ndikudalira ndemanga ndi malingaliro a madokotala.

Metformin (1000, 850, 500 mg) - zikuwonetsa, contraindication ndi mavuto. Mitu ya mankhwalawa

Moni, owerenga okondedwa komanso obwera kumene ku bulogu yanga. Lero, nkhaniyi ikunena za kuchiza kwa "matenda okoma" ngati imodzi mwazinthu zofunika kwambiri pa matenda ashuga. Ndawona kale zitsanzo zokwanira za zolakwika, zomwe sizinapangitse kusintha ndikukhumudwitsa ena.

Metformin hydrochloride - mayendedwe ndi mayina a malonda a mankhwalawo

Bizinesi yama pharmacological imawonedwa ngati imodzi yopindulitsa kwambiri ndipo kampani yokha yaulesi kwambiri siyipanga mankhwala omwe mankhwala ake ndi metformin.

Pakadali pano, mutha kupeza ma analogi ambiri omwe ali ndi mayina osiyanasiyana ogulitsa. Mwa iwo pali onse amtengo wokwera mtengo, pafupifupi wotchuka, ndipo osadziwika ndi aliyense, wotsika mtengo. Pansipa ndikuganiza kuti mudziwe mndandanda wamankhwala, koma choyamba tidzakumana ndi metformin yomwe.

Metformin yapadziko lonse

M'malo mwake, metformin ndi dzina ladziko lonse lapansi, kapena metformin hydrochloride. Metformin ndi m'gulu la Biguanides ndipo ndi woimira yekha. Mayina ena onse omwe amapezeka muchipatala ndi mayina amalonda amakampani osiyanasiyana omwe amapanga mankhwalawa.

Mukalandira kalata kuchokera kwa dokotala kuti mupeze mankhwala aulere ku pharmacy, dzinalo limalembedwa. Ndipo kampani yomwe ingakupatseni zimadalira kupezeka kwa mankhwala opangira mankhwala komanso kwa omwe akuwongolera apamwamba omwe amasayina chilolezo chogulitsa ichi kapena mankhwalawo. Ndanena kale m'nkhani yanga "Momwe mungachiritsire matenda ashuga a 2?", Chifukwa chake ndimalimbikitsa kuti ndiwerenge kaye.

Tiyerekeze kuti akuluakulu aboma asayina mgwirizano ndi Akrikhin, ndiye kuti mankhwalawo amangokhala ndi glyformin ndipo osagwiritsa ntchito glucophage kapena siofor. Chifukwa chake, musadabwe ndipo musalumbirire kwa madokotala kuti sakupatsani zomwe mukufuna. Ndi kuti sizimadalira iwo, ndipo izi sizoyenera kwa madokotala. Iwo alemba dzina generic mu Chinsinsi. Malamulo amenewo.

Zokonzekera zomwe zimakhala ndi metformin (mayendedwe osokoneza bongo ndi mayina ogulitsa)

Mankhwala aliwonse asanagulitsidwe, nthawi yambiri imadutsa, kwinakwake kuyambira zaka 10. Poyamba, kampani imodzi imakhudzidwa ndikukula ndikupanga mankhwala. Mankhwala oyamba omwe adatulutsidwa ndi kampaniyi ndi achikale. Ndiye kuti, kampani yomwe idakhazikitsa mankhwala omwe adayambitsa ndikuyipanga yoyamba, kenako ndikugulitsa patent yokha yopanga mankhwalawo kwa makampani ena. Mankhwala otulutsidwa ndi makampani ena azitchedwa mageneral.

Mankhwala oyamba azikhala okwera mtengo kuposa a generic, koma malinga ndi mtundu wake amakhalanso abwino, chifukwa adayesedwa muzomwe amaphatikizidwa, kuphatikiza ojambula mapiritsi kapena mapiritsi. Ndipo makampani opanga ma generic ali ndi ufulu wogwiritsa ntchito zinthu zina zothandiza komanso zothandiza, koma samayang'ananso ntchito yawo, chifukwa chake magwiridwewo akhoza kukhala otsika.

Mankhwala oyamba a metformin ndi GLUCOFAGE, (France)

Pali mitundu yambiri ya zamagetsi, ndipo ndikuwonetsa otchuka kwambiri:

• Siofor, (Germany)
• Forin Pliva, (Croatia)
• Bagomet, (Argentina)
• Gliformin, (Russia)
• Metfogamma, (Germany)
• Novoformin, (Russia)
• Foretin, (Russia)
• Metformin, (Serbia)
• Metformin Richter, (Russia)
• Metformin-Teva, (Israel)

Kuphatikiza pa izi, pali zokonzekera zambiri zomwe opanga aku India ndi Chitchaina, omwe amakhala zotsika mtengo kwambiri poyerekeza ndi zomwe zaperekedwa, komanso ali kutali ndi iwo pogwira ntchito bwino.

Palinso mankhwala omwe amakhala ndi nthawi yayitali, mwachitsanzo, glucophage yomweyo. Komanso metformin ikhoza kukhala gawo lokonzekera mophatikizana, monga glucovans, gluconorm, glybomet, yanumet, galvus met, amaryl M ndi ena.Koma zambiri za iwo munkhani zotsatirazi, chifukwa chake ndikukulangizani kuti mulembetse pazosintha za blog kuti musaphonye.

Ngati mungapeze metformin yaulere, pamaphikidwe okondera, ndiye kuti simuyenera kusankha. Ndipo aliyense amene adzagula ndi ndalama yake, amatha kusankha mankhwala oyenera kwambiri pamtengo ndi mtengo.

Njira zazikulu zoyeserera

Metformin ili ndi zotumphukira za hypoglycemic, zomwe zikutanthauza kuti sizilimbikitsa kubisirana kwa insulin ndi kapamba. Mankhwalawa ali ndi zotulukapo zambiri ndipo ndilembera zofunikira kwambiri, ndipo pazithunzi pansipa mutha kuwona zonse (dinani kuti mukulitse).

• kutsika kwamatenda a glycogen ku chiwindi, potero kumachepetsa kuyambira koyambirira kwa shuga m'magazi
• amalepheretsa kaphatikizidwe ka shuga kuchokera m'mapuloteni ndi mafuta
• kumapangitsa kutsika kwa shuga mu chiwindi
• kumawonjezera chidwi cha zotumphukira zolandilira ku insulin, potero kuchepetsa insulin
• amachepetsa kuyamwa kwamatumbo
• kuchuluka kutembenuka kwa glucose kuti agwirizane m'mimba
• imakhala ndi phindu pa lipids yamagazi, imachulukitsa kuchuluka kwa ma lipoproteins (HDL), imachepetsa cholesterol yathunthu, triglycerides ndi otsika kachulukidwe lipoproteins (LDL)
• kuchuluka kwa mayendedwe a glucose kudzera mu nembanemba kulowa mu minofu, i.e., kumathandizira kutulutsa kwa glucose

Popeza metformin ilibe mphamvu yokhudza kapamba, ilibe zotsatira zoyipa monga hypoglycemia (kuchepa kwambiri kwa shuga m'magazi), koma zina pambuyo pake.

Zizindikiro za Metformin

Mankhwala a Metformin si mankhwala antidiabetes okha. Mankhwalawa angagwiritsidwe ntchito:

• Ndi kulolerana kwa glucose komanso kusokoneza shuga. Ndinalemba kale za izi mu nkhani yanga "Zizindikiro ndi Zizindikiro za matenda a shuga", kuti mutha kudzidziwa nokha.
• Mankhwalawa kunenepa kwambiri, komwe kumayendetsedwa ndi insulin.
• Mankhwalawa cleopolycystic ovary (PCOS) mu gynecology.
• Ndi metabolic syndrome.
• Pofuna kupewa kukalamba.
• M'masewera.

Monga mukuwonera, metformin ili ndi mitundu yambiri yamapulogalamu, ndipo ndilankhula zochulukira pazinthu zanga zamtsogolo. Posachedwa, pali chidziwitso chakuti mankhwalawa amaloledwa kwa ana azaka 10 kuti athandizidwe ku matenda a shuga mellitus MODY ndi kunenepa kwambiri. Mukamamwa metformin, ndikofunikira kuti musamwe mowa, chifukwa chomwe ndanena pamwambapa.

Contraindication

Mankhwalawa ali otsutsana pazochitika zotsatirazi:

• mimba ndi mkaka wa m`mawere
• opaleshoni yayikulu ndi kuvulala
• vuto la chiwindi
• ana ochepera zaka 10
• Zakudya zama kalori ochepa (osakwana 1000 kcal patsiku), popeza pali acidization ya thupi, i.e, metabolic acidosis imayamba
• Kulephera kwa impso (mulingo wa creatinine ndi wamkulu kuposa 0.132 mmol / l mwa amuna ndi 0.123 mmol / l mwa akazi)
• m'mbuyomu lactic acidosis
• kupezeka kwa zinthu zomwe zikuyambitsa mkaka wa m'mawere

Ndikufuna kuganizira zomaliza mwatsatanetsatane. Chovuta china chovuta kwambiri cha kumwa mankhwalawa ndikupanga lactic acidosis (kuphatikizika kwa lactic acid), koma izi ndizosowa kwambiri, ndipo zimachitika ndi zovuta zomwe zimapangitsa kuti lactic acidosis iwonjezeke. Mibadwo yam'mbuyomu a Biguanides adachimwa ndi izi, ndipo kukonzekera kwa metformin ndikutheka kwachitatu, kotetezeka kwa mankhwalawa.

Zinthu zomwe zingapangitse kuti lactic acid iwonjezere komanso kuchulukitsa kwa lactic acidosis:

• aimpso ntchito, zomwe zimalepheretsa kuchotsa asidiyu mthupi
• uchidakwa wambiri ndi poyizoni wa ethanol
• matenda osachiritsika komanso owopsa omwe amachititsa kuti minofu ipume (kupuma komanso kulephera kwa mtima, kulowetsedwa kwam'mnyewa wam'mimba, matenda am'mimba a pulmonary)
• matenda ashuga ketoacidosis
• matenda opatsirana pachimake omwe amapezeka ndi kusowa kwamadzi (kusanza, kutsegula m'mimba, kutentha thupi)

Zikatero, ndikofunikira kuletsa mankhwalawo, mwina kwakanthawi, kufikira homeostasis ya thupi ibwezeretsedwa. Ndikulemba za mawonetseredwe a lactic acidosis mu gawo la bongo.

Chifukwa chiyani ndipo Metformin adasankhidwa kwa ndani?

Zowonetsa kutenga Metformin, zomwe zimaperekedwa mu malangizo a boma:

Type 2 shuga.

Type 1 shuga mellitus odwala omwe ali ndi kunenepa kwambiri komanso kukana insulin.

Komabe, zenizeni, anthu ambiri amatenga Metformin kuti achepetse thupi. Amanenanso zochizira polycystic ovary syndrome mwa akazi. Kuchita izi kumawonjezera mwayi wodwala kudziwa bwino.

Kuphatikiza pa kumwa mankhwalawa, amayi omwe ali ndi vuto la ovary polycystic ayenera kutsatira zakudya zamagulu ochepa. Izi zimawonjezera mwayi woganiza bwino.

Metformin: malangizo ogwiritsira ntchito

Kodi mankhwalawa amagwira ntchito bwanji?

Metformin amalembera odwala matenda a shuga a mtundu wachiwiri, ndipo nthawi zina amaphatikizidwa ndi mankhwala othandizira odwala matenda ashuga amtundu woyamba. Mankhwalawa amathandizira kuchepetsa shuga m'magazi pamimba yopanda kanthu ndikatha kudya, komanso amakupatsani mphamvu yochepetsa hemoglobin.
Kumwa mankhwalawa kumapangitsa kuti muchepetse kupanga kwa shuga m'chiwindi, komanso kumalepheretsa kuyamwa kwa mafuta ambiri m'matumbo. Chifukwa cha Metformin, ndizotheka kuwonjezera chidwi cha maselo kuti apange insulin. Zikondamoyo pa mankhwala sizipanga insulin yowonjezera, yomwe imalepheretsa kukula kwa hypoglycemia.

Mankhwalawa sadziunjikira m'thupi. Ambiri a iwo amachotseredwa ndi impso. Mankhwala omwe akhala akugwiritsidwa ntchito kwa nthawi yayitali atagwiritsidwa ntchito, mwachitsanzo, Glucofage Long, Metformin imatengedwa nthawi yayitali ngati mungayerekeze nthawi ino ndi mapiritsi a nthawi zonse.
Malinga ngati munthu ali ndi vuto linalake la impso, Metformin iyenera kuyikidwa mosamala.

Mukatenga nthawi yanji

Mankhwalawa amalembedwa kwa odwala omwe ali ndi matenda a shuga 2, omwe amakhala ndi kunenepa kwambiri komanso omwe ali ndi chiwopsezo chochepa cha maselo a insulin.
Kuchiza ndi metformin kuyenera kuchitika motsutsana ndi maziko azokwanira zolimbitsa thupi komanso kudya zakudya zochepa.

Mankhwala sangathe kumwa

Contraindication chithandizo ndi Metformin:

• Matenda a shuga ketoacidosis.
• Matenda a shuga.
• Kulephera kwamkati ndi glomerular kulowetsedwa kwa 45 ml / min ndikuchepera.
• Magazi a creatinine ndi 132 μmol / L kwa amuna ndi 141 μmol / L kwa akazi.
• Kulephera kwa chiwindi.
• Matenda opatsirana omwe ali pachimake gawo.
• Mowa
• Kuthetsa madzi m'thupi

Zomwe muyenera kulabadira mwapadera

Ngati wodwala wachita opaleshoni, kapena kumuyesa X-ray pogwiritsa ntchito kusiyanitsa, ndiye kuti ayenera kusiya kumwa Metformin patatsala masiku awiri asanafike pochita.
Nthawi zina odwala amatha kukhala ndi vuto lalikulu lactic acidosis. Izi zimatsatiridwa ndi kuchepa kwa magazi pH mpaka 7.25, yomwe imabweretsa chiwopsezo chachikulu osati thanzi komanso moyo. Chifukwa chake, pamene zizindikiro monga kupweteka kwam'mimba, kufooka kowonjezereka, kusanza ndi kupuma movutikira kuwonekera, ambulansi iyenera kuyitanidwa.
Monga lamulo, lactic acidosis imayamba pokhapokha ngati munthu wamwa mlingo waukulu kwambiri wa mankhwalawo, kapena chithandizo chinkachitika ngati pali zotsutsana. Nthawi zina, chithandizo cha Metformin sichimatsogolera pakukula kwa lactic acidosis.

Momwe mungatengere komanso mlingo

Kuchiza kuyenera kuyamba ndi mlingo wochepa wa 500-850 mg patsiku. Pang'onopang'ono, imawonjezeka ndikukula mpaka 2550 mg patsiku, kumwa piritsi limodzi la 850 mg katatu patsiku. Kuchulukaku kuyenera kuchitika nthawi 1 m'masiku 7-10.
Ngati munthu agwiritsa ntchito mankhwala okhala ndi nthawi yayitali kuchitira mankhwala, tsiku lililonse mlingo umachepetsedwa mpaka 2000 mg.Imwani mankhwalawa 1 nthawi patsiku, musanakagone.

Zotsatira zoyipa zimafotokozedwera mu mawonekedwe amisala pakuchitika kwa dongosolo la m'mimba. Munthu amadwala matenda otsekula m'mimba, nseru, kusanza, kulakalaka kwake kudya, kuonda kwake kungasokonekera. Monga lamulo, chisokonezo chotere chimawonedwa m'masiku oyambira okha kuyambira pachiyambire mankhwala.
Kuchepetsa mwayi wokhala ndi zotsatirapo zochepa, chithandizo chikuyenera kuyambitsidwa ndi Mlingo wochepa.
Ngati wodwala ali ndi zotupa pakhungu komanso kuyabwa, ndiye kuti izi zimafunikira upangiri wa udokotala, chifukwa zingasonyeze kuti munthu alibe vuto lakelo.
Pa chithandizo cha nthawi yayitali, kuperewera kwa vitamini B12 m'thupi ndikotheka.

Kuchepetsa ndi pakati

Pakubala kwa mwana komanso poyamwitsa, mankhwalawa saikidwa kwa akazi. Komabe, nthawi zambiri amagwiritsidwa ntchito pochiza polycystic ovary syndrome. Ngati panthawiyi mayi ali ndi pakati, ndiye kuti palibe chowopsa chomwe chidzachitike. Ndikofunika kuti musamwe mankhwalawo mukazindikira za vuto lakelo.

Ngati mlingo waukulu watengedwa

Ndi mankhwala osokoneza bongo, hypoglycemia samakula, koma lactic acidosis imatha kuchitika (pafupifupi 32% ya milandu). Munthu ayenera kugonekedwa kuchipatala mwachangu. Kuti muchotse mankhwalawo mwachangu m'thupi, kuyimba pamafunika. Mofananamo, chithandizo chamankhwala chimachitika.

Kuchita ndi mankhwala ena

Ndi munthawi yomweyo makonzedwe a Metformin omwe ali ndi insulin, kuchepa kwakukulu kwa shuga m'magazi ndikotheka. Komanso, mankhwalawa amatha kuthana ndi mankhwala kuti muchepetse kuthamanga kwa magazi ndi mankhwala ochizira matenda a mtima.

Fomu yotulutsidwa, malo osungira

Mankhwalawa amatha kupezeka pamankhwala a 500, 850 ndi 1000 mg. Ikupezeka piritsi.
Kutentha kozungulira sikuyenera kupitirira 25 ° C. Moyo wa alumali umasiyana zaka zitatu mpaka zisanu.

Prediabetes ndi Metformin

Metformin itha kumwa mankhwala onenepa a prediabetes. Izi zikuchepetsa mwayi wokhala ndi matenda ashuga amtundu wa 2.

Choyamba muyenera kuyesera kuchepetsa thupi ndi zakudya. Ngati zotsatira zake sizikwaniritsidwa, ndiye kuti mutha kulumikiza mankhwala. Kuphatikiza pa zakudya, munthu ayenera kuwonjezera zochita zake zolimbitsa thupi: kuchita masewera olimbitsa thupi, kuyenda kwambiri, kuthamanga. Mofananamo, ndikofunikira kuyang'anira kuchuluka kwa kuthamanga kwa magazi, komanso kuchuluka kwa shuga m'magazi, kuphatikizapo kusala kudya.

Kodi maphunzirowa atenga nthawi yayitali bwanji?

Metformin si mankhwala. Zimatengedwa mu moyo wonse, popanda zosokoneza, tsiku ndi tsiku.

Ngati munthu wayamba kutsegula m'mimba kapena matenda ena am'mimba, ndiye kuti ichi sichiri chifukwa chosiya kumwa. Ndizotheka kuti muchepetse mlingo kwakanthawi.

Kamodzi pa miyezi isanu ndi umodzi, kuyezetsa magazi kuyenera kutengedwa kuti athe kudziwa kuchuluka kwa vitamini B12 m'thupi. Ngati pali kuchepa, ndiye kuti iyenera kutengedwa padera. Palinso malingaliro kuti mutenge vitamini B12 ngati njira yothanirana.

Zakudya ndi Metformin

Kuti muchepetse kunenepa kwambiri, komanso munthawi ya matenda a shuga, muyenera kutsatira zakudya zochepa zamafuta. Sikokwanira kungodula zopatsa mphamvu za tsiku ndi tsiku ndi kuchuluka kwa mafuta omwe amamwetsedwa - izi sizingakuthandizeni kuti mulibe shuga. Kuphatikiza apo, kudya zakudya zamafuta ochepa kumathandizanso kuti munthu azikhala ndi chidwi chofuna kudya, zomwe zimapangitsa kuti azidya kwambiri, azisokonekera komanso akhale ndi thupi lolemera.

Ngati simukuchepetsa kuchuluka kwa chakudya chamafuta omwe mumamwe, ndiye kuti simungathe kukwaniritsa zochizira pakumwa mapiritsi ngakhale mutaba jakisoni wa insulin. Kudya zakudya zoyenera kumakuthandizani kukhala odzala ndi kupewa kunenepa kwambiri.

Ndi mankhwala ati oti musankhe: Metformin, Siofor kapena Glucofage?

Glucophage ndi mankhwala oyamba ozikidwa metformin. Siofor ndi mankhwala ena omwe ali ndi fanizo.

Glucophage Long - chida chokhala ndi mphamvu yokhalitsa. Kuwongolera kwake sikungapangitse kuyambitsa zovuta pamtundu wa m'mimba kuposa mankhwala ochiritsira ofanana ndi metformin. Glucophage Long imatengedwa asanagone, zomwe zimalepheretsa kulumpha m'mawa m'magazi.

Mtengo wa Glucofage ndi Glucophage Long kukonzekera sikokwanira. Chifukwa chake, sizikupanga nzeru kusinthira kumafanizo awo. Chofunika kupulumutsa sichitha.

Metformin yokhala yayitali kwa nthawi yayitali - ndi kusiyana kotani?

Ngati munthu watenga metformin wokhazikika, mankhwalawa amamwetsa mwachangu kwambiri. Pambuyo 4 mawola kudya magazi, ambiri pazomwe amagwira zimawonedwa. Fotokozerani mankhwala katatu patsiku ndi chakudya.

Munthu akatenga metformin yomasulidwa kwa nthawi yayitali, mankhwalawa amamwa nthawi yayitali, koma amakhalanso nthawi yayitali. Fotokozerani mankhwalawa 1 nthawi patsiku, musanakagone. Izi zithandiza kupewa m'mawa kwambiri.

Metformin yokhala yayitali sichimayambitsa zotsatira zoyipa mwanjira yakuphwanya kugwirira ntchito pamimba. Komabe, amawongolera kuchuluka kwa shuga masana. Chifukwa chake, ndikulimbikitsidwa kuvomerezedwa kwa anthu omwe ali ndi shuga othamanga kwambiri. Mankhwala oyamba a metformin ndi Glucofage Long. Pogulitsa palinso fanizo la mankhwalawa ndi mphamvu yayitali.

Zotsatira za metformin pachiwindi. Mafuta hepatosis ndi metformin

Metformin sayenera kumwedwa ndi kuwonongeka kwambiri kwa chiwindi, mwachitsanzo, ndi matenda a cirrhosis kapena chiwindi. Ndi mafuta a chiwindi hepatosis, kugwiritsa ntchito kwake, m'malo mwake, kudzabweretsa zabwino zambiri. Kuphatikiza apo, wodwalayo afunika kutsatira zakudya zamagulu ochepa. Mukamatsatira malangizowa, mudzatha kukonza moyo wawo mwachangu. Fatpat hepatosis imatha kugonjetsedwa kudzera muzakudya zoyenera komanso Metformin. Mofananamo, munthu amayamba kuchepa thupi.

Metformin ndi mahomoni

Metformin siyimakhudzanso potency ya amuna ndi kuchuluka kwa magazi a testosterone.

Ndi polycystic ovary syndrome mwa akazi, mahomoni ambiri ogonana amuna amawonedwa, komanso kusokonezeka kwa metabolic ndi insulin kukana. Kutenga metformin, mwachitsanzo, Siofor, kuchotsa vuto lomwe liripo. Mankhwalawa amathandizanso kukongoletsa maimidwe achikazi ndipo kumawonjezera mwayi woti akhale ndi chiyembekezo.

Ndi mankhwala ati omwe amayenera kumwa m'malo mwa metformin chifukwa cha kulephera kwa impso?

Kutenga Metformin chifukwa cha kulephera kwa impso nkoletsedwa. Silembedwera odwala omwe ali ndi matenda ashuga omwe amachepetsa mpaka kulowa kwa 45 ml / miniti.

Ndi kulephera kwa aimpso, mutha kumwa mankhwala monga Januvia, Galvus, Glyrenorm. Kukhazikitsidwa kwa jakisoni wa insulin ndikothekanso. Mulimonsemo, dokotala yekha ndiye ayenera kupereka mankhwala kwa odwala omwe ali ndi mavuto otere.

Metformin imakulitsa moyo - sichoncho?

Metformin bwino imathandizira kutalikitsa kwa moyo wa anthu omwe akudwala matenda ashuga, chifukwa amaletsa kukula kwa zovuta zovuta za matendawa.

Ponena za kuchuluka kwa chiyembekezo cha moyo mwa odwala omwe alibe matenda a shuga, palibe umboni wa sayansi pazowona izi. Komabe, kafukufuku wokhudza nkhaniyi wayambitsidwa kale.

Mutha kupezanso ndemanga kuti chithandizo ndi Glucofage chimachepetsa ukalamba. Izi zimatsimikiziridwa ndi anthu omwe samamwa mankhwala a shuga.

Prophylactic Metformin ndi mlingo wake

Ngati munthu ndi wonenepa kwambiri, ndiye kuti amatha kutenga Metformin kuti ikhale prophylactic.Mankhwalawa amakupatsani mwayi kuti muchepetse ma kilogalamu angapo a kulemera kowonjezera, komanso kubweretsanso kuchuluka kwa cholesterol, komwe kumathandiza kupewa matenda ashuga amtundu wa 2.

Musanayambe mankhwala othandizira kupewa, muyenera kuphunzira malangizo oti mugwiritse ntchito ndikuonetsetsa kuti palibe zotsutsana.

Ndikulimbikitsidwa kuti muthe kutenga Metformin muli ndi zaka 35 mpaka 40, ngakhale palibe zomwe zasinthidwa pazomwezi. Kuphatikiza pa kuwongolera zolemetsa zamankhwala, muyenera kutsatira zakudya zochepa zamanyama. Tiyenera kumvetsetsa kuti kuchuluka kwa mapiritsi kumakhala kocheperako ngati mukupitiliza kudya mosayenera. Zomwe zimavulaza kwambiri ndizinthu zomwe zimakhala ndi shuga woyengetsa.

Anthu onenepa amafunika kumwa Metformin pa 2550 mg tsiku lililonse. Ngati mankhwalawa akuchitika ndi mankhwala okhala ndi mphamvu yayitali, ndiye kuti tsiku lililonse mlingo uyenera kukhala 2000 mg. Muyenera kuukweza bwino. Pakati pa sabata yoyamba, zidzakhala zokwanira kumwa 500-850 mg wa mankhwalawa patsiku. Izi zimalola thupi kuti lizolowere mankhwala.

Ngati munthu alibe vuto lolemera mopitirira muyeso, ndipo akufuna kutenga Metformin kuti aletse kukalamba koyambirira, ndiye kuti ndikokwanira kumwa 500-1700 mg ya mankhwalawa patsiku. Palibe zidziwitso zatsopano pankhaniyi.

Metformin yochepetsa thupi

Metformin imakupatsani mphamvu kuti muchepetse thupi popanda kuvulaza thanzi, chifukwa mankhwalawa samabweretsa zovuta zoyipa. Kuphatikiza apo, ndi thandizo lake ndikotheka kutulutsa mtundu wa cholesterol ndi glucose m'magazi.

Popeza izi, sizodabwitsa kuti metformin imakonda kugwiritsidwa ntchito pakuchepetsa thupi. Zomwe zachitika ndikutenga zaka zopitilira 50. Mankhwala opangidwa ndi Metformin amapangidwa ndi makampani ambiri azamankhwala. Izi zimakuthandizani kuti musunge mtengo wa mankhwala oyambilira Glucofage pamlingo wotsika.

Pofuna kusokoneza kukula kwa zoyipa, metformin iyenera kutengedwa mu yaying'ono Mlingo woyamba. Musanayambe ndewu yolimbana ndi kunenepa kwambiri, muyenera kuonetsetsa kuti munthu alibe zotsutsana ndi mankhwalawa.

Kodi mungataye ndalama zingati ndi metformin?

Ngati simukumanganso zakudya zanu komanso osachita masewera olimbitsa thupi, ndiye kuti simungathe kuchita bwino chifukwa chochepetsa thupi kuposa makilogalamu 2-4.

Pambuyo miyezi 1.5-2 kuyambira poyambira kumwa metformin, zotulukapo zake palibe, ndipo kulemera kumakhalabe pamigawo yapitayi, izi zitha kuwonetsa kuti munthuyo ali ndi hypothyroidism. Onetsetsani kuti mwakumana ndi katswiri ndikupanga mayeso a mahomoni a chithokomiro.

Kutsatira zakudya zamafuta ochepa ophatikizidwa ndi metformin kumachepetsa kwambiri kulemera kwa makilogalamu 15 kapena kuposerapo. Kuti musunge izi, muyenera kutenga Metformin mosalekeza. Mutasiya mapiritsiwo, kulemera kwake kumatha kubwerera.

Kodi Elena Malysheva amalangiza metformin kuti achepetse thupi?

Elena Malysheva akuti metformin ndi njira yothanirana ndi ukalamba, koma sakusonyeza za kuthekera kwake kuchepetsa kunenepa kwambiri. Wowonetsa TV yemwe amadziwika kwambiri amavomereza kuti azitsatira zakudya zake, osamwa mankhwala osokoneza bongo. Komabe, muyeso wotere suyenera kwa munthu aliyense.

Metformin ndi hypothyroidism

Metformin imatha kutengedwa ndi hypothyroidism, popeza matendawa sasonyezedwa ngati cholakwira. Amaloledwa kugwiritsidwa ntchito molumikizana ndi mankhwala othandizira hypothyroidism. Ndizotheka kuti izi zikuthandizani kuti muchepetse thupi komanso mukhale ndi thanzi labwino. Komabe, adotolo ayenera kutenga nawo mbali pamankhwala a hypothyroidism, ndipo metformin ilibe vuto pamatendawa.

Metformin ndi matenda a shuga a 2

Metformin ndi mankhwala ochizira matenda amishuga amtundu wa 2, omwe amakupatsani mwayi kuti muchepetse shuga pambuyo pudya komanso pamimba yopanda kanthu.Kugwiritsa ntchito metformin kumakupatsani mwayi wopewa kukula kwa zovuta zovuta za matenda, kuyimitsa kupitilira kwake komanso osavulaza thanzi. Metformin sayenera kuonedwa ngati machiritso ozizwitsa omwe angathandize kuthana ndi matenda ashuga. Zachidziwikire, panali zochitika pomwe munthu adalimbana ndi kunenepa kwambiri, ndipo matendawa amachepetsa, omwe amalola kusiya kugwiritsa ntchito metformin, koma zochitika ngati izi ndizosowa.

Ngati munthu amatenga metformin pafupipafupi komanso kwanthawi yayitali, ndiye kuti izi zimapangitsa kuti shuga, cholesterol ndi triglycerides m'magazi komanso kuchepa thupi.

Metformin ndi mankhwala otetezeka, motero, amapatsidwa mankhwala ochizira matenda osokoneza bongo komanso kunenepa kwambiri kwa ana opitirira zaka 10. Muyenera kuyamba kumwa mankhwalawa osachepera 500-850 mg patsiku, pang'onopang'ono kubweretsa kuchuluka kwa tsiku lililonse kwa 2250 mg. Ngati mankhwala Glucofage Long amagwiritsidwa ntchito pochiza, ndiye kuti mlingo wosakwana 2000 mg uyenera kumwedwa patsiku.

Kusunga matenda a shuga komanso kulemera pansi moyang'aniridwa ndi chithandizo chamankhwala sikungathandize. Wodwala amafunika kutsatira zakudya. Kupanda kutero, matenda a shuga akupitabe patsogolo ndikupangitsa kuti pakhale zovuta zazikulu.

Ndi mankhwala ati a metformin amene amachepetsa kwambiri shuga?

Zochizira matenda a shuga, glucophage ndiyabwino. Ichi ndi mankhwala oyambira pamtengo wotsika mtengo kwa anthu ambiri. Muthanso kutenga ma analog ake Siofor.

Kuti muchepetse shuga m'magazi kuti muuke m'mawa, mutha kugwiritsa ntchito mankhwala Glucofage Long. Amatengedwa asanagone, choncho amagwira ntchito usiku wonse. Njira izi zikapanda kukhazikika shuga, jakisoni wa insulin ingafunike. Kumbukirani kuti kuwuka kwam'magazi m'magazi kumathandizira kuti pakhale zovuta zamagulu a shuga. Chifukwa chake, kudumpha koteroko sikunganyalanyazidwe.

Ngati ndatsegula m'mimba kuchokera ku metformin kapena sizithandiza, ndiye kuti ndi chiyani chomwe chitha kusintha?

Ndikosavuta kupeza m'malo mwa metformin - ndi chinthu chapadera chochepetsera shuga m'magazi.

Chifukwa chake, choyamba muyenera kuyesa kupewa kupewa kutsekula m'mimba, kuti musayang'ane m'malo mwa metformin. Kuti muchite izi, yambani kulandira chithandizo cha mankhwala ochepa. Izi zimalola kuti thupi lizolowera mankhwalawo ndipo osayankhidwa chifukwa cholephera kugaya chakudya.

Wosagwira pang'onopang'ono mankhwala amachititsa kutsegula m'mimba. Chifukwa chake, kwakanthawi mutha kusintha m'malo mwa mapiritsi a Metformin.

Ngati kumwa mankhwalawa sikuchepetsa shuga m'magazi, ndiye kuti munthu atha kudwala matenda ashuga amtundu woyamba. Nthawi yomweyo, kapambayu wachotsa mphamvu zake zonse ndipo sanatulutsenso insulin. Kenako muyenera kusinthana ndi jakisoni wa timadzi timeneti. Kupanda kutero, munthu akhoza kufa chifukwa cha zovuta za shuga. Mapiritsi ayenera kutayidwa.

Pomwe metformin imatsitsa shuga m'magazi, koma izi sizokwanira, chithandizo chitha kuphatikizidwa ndi jakisoni wa insulin, koma muyezo waukulu.

Ngati munthu ali ndi thupi lochepa, koma amadwala matenda a shuga, ndiye kuti odwala oterowo amafunikira kupatsidwa insulin yomweyo. Mankhwala omwe amawotcha shuga sangakuthandizeni kuti mupirire matendawa.

Kutenga metformin kumabweretsa kuwonjezeka kwa shuga m'magazi, chifukwa chake nchiani?

Metformin sichithandiza shuga m'magazi ngati mtundu wachiwiri wa shuga ndi woopsa, kapena munthu akapezeka ndi matenda a shuga a mtundu woyamba. Pankhaniyi, jakisoni wa insulin adzafunika, komanso kudya.

Dokotala atha kukuthandizani kuti mulandire kapena kuwonjezera kukonzekera kwa metformin ndi mankhwala monga: Diabeteson MV, Amaril, Manil, ndi zina.Ngati kugwiritsa ntchito kwawo sikulola kukwaniritsa zomwe mukufuna, ndiye kuti muyenera kusinthira jakisoni wa insulin. Kukana insulin mankhwala sayenera. Komanso, kumwa mankhwala kumatha kuchepetsa mlingo wa insulin nthawi 2-7. Izi zimakuthandizani kuti musunge shuga komanso kuti musawononge thanzi lanu.

Chithandizo cha matenda a shuga ndi metformin ndi jakisoni wa insulin

Nthawi zambiri, kukonzekera kwa metformin kumayikidwa mu regimen zovuta ndi jakisoni wa insulin. Izi zidzakonza kuchuluka kwa shuga pa 4.0-5.5 mmol / L.

Kupyola pakudya ndi pakamwa pobayira mankhwala owotcha shuga omwe shuga amatha kuyatsidwa ngati ali pachiwopsezo chomakula. Nthawi zina, Mlingo wambiri wa insulin amafunikira. Izi ndizothandiza kwa odwala omwe mulingo wa shuga sagwera pansi pa 6.0-7.0 mmol / L. Ndi zizindikirozi, zovuta za matenda ashuga zipita patsogolo, ngakhale osati mwachangu kwambiri.

Ngati tilingalira za njira zochizira matenda osokoneza bongo, choyamba tiyenera kuyesa kukonza zakuphwanya mothandizidwa ndi dongosolo lazakudya zopatsa thanzi komanso zolimbitsa thupi. Pokhapokha amayamba kumwa mankhwala owotcha shuga. Mphamvuyo ikakhala kuti singatheke, jakisoni wa insulin akusonyezedwa. Mlingo wa insulin ufunika kuchepetsedwa ndi 25% ngati nthawi yomweyo munthu alandire kukonzekera kwa metformin. Kuchulukitsa mlingo wa insulin panthawi ya mankhwala omwe amawotcha shuga amawopseza kukula kwa hypoglycemia.

Kuphatikiza pa njira zakuchiritsira zomwe zili pamwambapa, odwala matenda ashuga ayenera kusewera masewera. Zimathandizira kuchepetsa kuthamanga kwa matenda kapena, monga amatchedwanso, qi-run. Mutha kusinthanso zochita zanu zolimbitsa thupi ndi kuyenda kwa Nordic.

Metformin: kuvomera bwanji?

Metformin imatengedwa ndi zakudya, zomwe zimachepetsa chiopsezo cha mavuto.

Mapiritsi okhala ndi nthawi yayitali ayenera kumwa kwathunthu popanda kutafuna. Amakhala ndi matrix a cellulose, omwe amachititsa kuti pang'onopang'ono kumasulidwa kwa chinthu chachikulu chogwira ntchito. Kuwonongeka kwa matrix kotere kumachitika m'matumbo. Pankhaniyi, kusintha kwa kusunthika kwa chopondacho ndikotheka, koma popanda kutsegula m'mimba. Izi sizimabweretsa ngozi.

Kodi ndingatenge metformin popanda kufunsa dokotala?

Mankhwala a Metformin amagawidwa ku mankhwala osokoneza bongo popanda mankhwala, kotero munthu amatha kuwagula osakacheza ndi dokotala kale. Musanayambe kugwiritsa ntchito mankhwalawa, muyenera kuwonetsetsa kuti wodwala alibe zotsutsana ndi ntchito yake. Ndikofunika kuyesa magazi chifukwa cha ichi. Ikuwunika momwe chiwindi ndi impso zimayendera. Kuyesedwa koteroko kumayenera kuchitika kamodzi kamodzi m'miyezi 6. Ndikofunikanso kuwongolera kuchuluka kwa cholesterol m'magazi komanso kuchuluka kwa kuthamanga kwa magazi, zomwe zimapangitsa kuti pakhale zovuta zodwala zamtima.

Mlingo wa metformin wokwanira tsiku ndi tsiku ndi zingati?

Onse ochepetsa thupi komanso pochiza matenda amtundu wa 2 wodwala, wodwalayo amapatsidwa 2550 mg ya metformin tsiku lililonse. Pankhaniyi, munthu ayenera kumwa piritsi limodzi la mankhwala 3 katatu patsiku. Mlingo wa mankhwalawa ndi 850 mg.

Ngati mankhwala omwe atulutsidwa nthawi yayitali atagwiritsidwa ntchito pochiza, ndiye kuti mlingo wambiri tsiku lililonse ndi 2000 mg. Kuti muchite izi, imwani mapiritsi 4 a 500 mg a mankhwala Glucofage kale musanagone.

Mlingo woyamba wa mankhwalawa ukhale wocheperako: 500 kapena 850 mg. Kenako, kutsatira momwe thupi limagwirira ntchito, mlingo wake umayamba kuwonjezeka. Kuyenda pang'onopang'ono kumalepheretsa kukula kwa zovuta m'matumbo am'mimba.

Ngati munthu angaganize kutenga metformin kuti achepetse moyo wobwera, ndikulimbikitsidwa kusunga mlingo wa 500-1700 mg patsiku, koma osatinso.

Kodi zotsatira zake zimatenga nthawi yayitali bwanji?

Metformin yokhala ndi nthawi yayitali imagwira ntchito kwa maola 8-9.Mapiritsi a metformin amchikhalidwe amakhalabe ndi zotsatira zosaposa maola 6. Ngati mlingo wotsatira watengedwa kumwa mankhwala asanachitike, musadandaule. Sizowononga thanzi. Ndikofunika kuonetsetsa kuti palibe mankhwala osokoneza bongo omwe amachitika. Pachifukwa ichi, mankhwalawa sayenera kumwedwa mopitirira muyeso wa tsiku lililonse.

Kodi metformin ikhoza kuphatikizidwa ndi ma statins?

Metformin imatha kutengedwa ndi ma statins, omwe amathandiza kuchepa kwa mafuta m'thupi. Ngati nthawi yomweyo munthu amatsatira zakudya, ndiye kuti zidzakhala zotheka kuti asamangokhala cholesterol, komanso triglycerides, komanso mgwirizano wa atherogenicity. Komanso, kudya metformin ndikudya chakudya kwakanthawi kumatha kukulolani kusiya kumwa. Menyu wokhala ndi zopatsa mphamvu zamagalimoto ambiri umakupatsani mwayi kuti muchotse madzi ochulukirapo m'thupi, muchotse edema, komanso muchepetse magazi. Chifukwa chake, madokotala amalimbikitsa pang'onopang'ono kuchepetsa Mlingo wa mankhwalawa zochizira mtima, kenako mutha kuzisiyiratu. Ndizotheka kuti zitha kuyimitsa mankhwalawa ndi mankhwala okodzetsa.

Kodi metformin ikhoza kuphatikizidwa ndi mowa?

Mankhwalawa ndi mankhwala a metformin, ndizovomerezeka kugwiritsa ntchito milingo yaying'ono ya mowa. Komabe, muyenera kuyang'anira kuchuluka kwa mowa womwe umamwa, sikuletsedwa kuledzera.

Palibe chifukwa chokhazikitsira pakati pakumwa mankhwala kapena kumwa mowa. Ndiye kuti, mumatha kumwa mowa nthawi yomweyo.

Ngati simumayang'anira kumwa komanso kumwa kwambiri mowa, ndiye kuti kwa odwala matenda ashuga izi zikuwopseza kukula kwa lactic acidosis. Ili ndi vuto lalikulu lomwe lingayambitse imfa. Chifukwa chake, uchidakwa umakhala wowopsa thanzi.

Mutha kupeza ndemanga zambiri zabwino zakugwiritsa ntchito metformin pochiza matenda ashuga komanso kunenepa kwambiri. Nthawi zambiri, odwala komanso madokotala amalimbikitsa kugwiritsa ntchito mankhwalawa Glyukofazh ndi Glukofazh Long, ngati mankhwala oyambira. Mofananamo, muyenera kutsatira zakudya, zomwe zingakuthandizeni kuchepetsa shuga.

Ndemanga zoyipa nthawi zambiri zimasiyidwa ndi anthu omwe samatsatira zakudya zamafuta ochepa ndikukhala ndi moyo wopanda thanzi. Pankhaniyi, sizingatheke kuthana ndi matendawa ngakhale mothandizidwa ndi mankhwala.

Mutha kupezanso ndemanga zabwino zogwiritsa ntchito metformin yokhala ndi zotumphukira za sulfonylurea, popeza njira yofananira imathandizira kuchepetsa misempha ya magazi. Komabe, ngati mumatsatira mankhwalawa kwa nthawi yayitali, pamakhala chiopsezo chotsika cha mashuga a pancreatic ndikusintha kwa mtundu wa 2 matenda ashuga.

Odwala ambiri amawonetsa kuti glucophage satha kuyambitsa zotsatira zoyipa mwanjira yakumbuyo. Chifukwa chake, ndibwino kusankha mankhwalawa oyambira mankhwala a metformin, osati otchulidwa ake. Kuphatikiza zakudya komanso masewera olimbitsa thupi, kutenga Metformin kukuthandizani kuti muchepetse thupi.

Za adotolo: Kuyambira 2010 mpaka 2016 Othandizira pachipatala chachipatala chapakati chaumoyo Na. 21, mzinda wa elektrostal. Kuyambira mu 2016, agwira ntchito ku malo ozindikira matenda No. 3.

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Mlingo ndi njira yoyendetsera metformin

Monga lamulo, mankhwalawa amaperekedwa kale pazizindikiro zoyambirira za matenda osokoneza bongo ndipo izi zimapangitsa kuti asankhidwa, chifukwa mankhwalawo amalembedwa pa nthawi yake, ndipo izi zikuchitika kale 50%. Kuti muyambe, ndikukuwuzani mtundu wa metformin hydrochloride wopangidwa. Masiku ano, pali mitundu iwiri ya mankhwala omwe amasiyana pakanthawi kochedwa: fomu yowonjezera ndi mawonekedwe abwinobwino.

Mitundu yonseyi imapezeka pamapiritsi, koma imasiyana.

• Metformin yachilendo imapezeka mu Mlingo wa 1000, 850 ndi 500 mg.
• Metformin yayitali imapezeka mu Mlingo wa 750 ndi 500 mg

Kuphatikiza mankhwala, metformin ikhoza kukhala mu mlingo wa 400 mg. Mwachitsanzo, mu glibomet.

Mlingo woyambirira wa mankhwalawa ndi 500 mg kokha patsiku. Mankhwala amatengedwa mosamalitsa pambuyo kapena pakudya katatu patsiku. M'tsogolomu, pakatha milungu iwiri, ndizotheka kuwonjezera kuchuluka kwa mankhwalawa malinga ndi kuchuluka kwa shuga. Mlingo wapamwamba wa metformin patsiku ndi 2000 mg.

Ngati mumwa mankhwalawa musanadye, ndiye kuti mphamvu ya metformin imatsika kwambiri. Kumbukirani kuti mtundu uwu wa hypoglycemic umapangidwa kuti ukhale wamphamvu m'magazi a glucose, osadya. Muyenera kukumbukiranso kuti popanda kuchepetsa zakudya zam'mimba, mphamvu ya mankhwalawa ndiyotsika kwambiri. Chifukwa chake muyenera kudya mukamamwa metformin molingana ndi mfundo zapakati pazakudya za shuga ndi kunenepa kwambiri.

Metformin ikhoza kuphatikizidwa ndi mankhwala ena ochepetsa shuga ndi insulin kuti mukwaniritse zotsatira zabwino kwambiri. Kuti muwone momwe mankhwalawa amathandizira, musathamangire ndipo nthawi yomweyo muziyembekezera kuchepa kwa glucose. Muyenera kudikirira masabata 1-2 mpaka mankhwalawo atakula kwambiri.

Pambuyo pake, tikulimbikitsidwa kuwunika kuchuluka kwa shuga m'magazi (m'mawa mpaka m'mawa) pogwiritsa ntchito glucometer (mwachitsanzo, Contour TC), komanso musanadye chakudya musanakagone. Koma muyenera kuwonetsetsa kuti nthawi yodyera isanathe maola 4-5. Ngati phindu la shuga la magazi silikufikika munthawi imeneyi, ndiye kuti mutha kukulitsa mlingo, koma osapitirira pazovomerezeka.

Kodi ndingatenge metformin mpaka liti?

M'malo mwake, palibe yankho lomveka bwino la funso ili. Kutalika kwa ntchito kumadalira zolinga ndi zisonyezo poika metformin. Ngati zolinga za kanthawi kochepa zikwaniritsidwa, mwachitsanzo, kuchepa thupi, ndiye kuti metformin imathetsedwa mukangokwaniritsa. Ndi matenda a shuga, kagayidwe kazakudya umachepa kwambiri ndipo n`zotheka kuti mankhwalawa amayenera kuperekedwa kwa nthawi yayitali. Mulimonsemo, muyenera kusankha funso lokhudza kumwa mankhwala ndi dokotala. Mwa njira, ndidalemba cholembedwa chokhudza kugwiritsa ntchito zakudya, ndikupangira kuwerenga "Metformin kuti muchepetse thupi: mutani?".

Ndikukupatsirani matenda kuchipatala poika metformin (dinani chithunzichi kuti chikhale chokulirapo).

Kuthandiza ndi mankhwala osokoneza bongo a metformin

Ndi mankhwala osokoneza bongo a metformin, hypoglycemia sizichitika, koma lactic acidosis kapena lactic acidosis imayamba. Izi ndizovuta kwambiri zomwe zitha kutha. Itha kuchitika ndikusakanikirana kwa zinthu zomwe zimatsogolera ku hypoxia komanso kugwiritsa ntchito metformin. Pamwambapa, ndinakuwuzani kuti izi zitha bwanji.

Zizindikiro za lactic acidosis ndi:

• kusanza ndi kusanza
• kutsegula m'mimba
• kupweteka kwambiri pamimba
• kutsitsa kutentha kwa thupi
• kupweteka kwa minofu
• kupumira msanga
• chizungulire
• kulephera kudziwa

Munthu akapanda kuthandizidwa, nthawi yomweyo amayamba kugwa, kenako kufa.

Kodi thandizo ndi lactic acidosis ndi chiyani? Choyamba, kuthetsedwa kwa metformin komanso kugonekedwa kuchipatala mwachangu. M'mbuyomu, izi zimachitika ndi kulowetsedwa kwa sodium bicarbonate (koloko), koma chithandizo choterechi ndi chowopsa kuposa chabwino, chifukwa chake chidasiyidwa kapena kuchitidwa mwanjira zina.

Momwe mungasinthire metformin

Pali nthawi zina pomwe mankhwalawo sioyenera kapena pali zotsutsana pazolinga zake. Momwe mungachitire ndi zomwe zingalowe m'malo mwa metformin? Ngati izi ndizosagwirizana kwambiri ndi mapiritsi, ndiye kuti mutha kuyesa kusintha kuti ikhale mankhwala a kampani ina, koma kuti mulinso ndi metformin, ndiye kuti, mwa kuyankhula kwina, sinthani ndi analogue.

Koma pakakhala chosokoneza chilichonse, kusinthanitsa ma analogue sikungathetse vutoli, chifukwa kumakhala ndi zotsutsana zomwezo. Pankhaniyi, metformin ikhoza kulowa m'malo mwa mankhwala otsatirawa, omwe amakhalanso ndi machitidwe ofanana:

1. DPP-4 inhibitor (Januvia, galvus, onglise, trazenta)
2. fanizo la GLP-1 (byeta ndi victosa)
3. thiazolidinediones (avandium and actos)

Koma kusintha mankhwala ndikofunikira moyang'aniridwa ndi adokotala.

Chifukwa metformin sichithandiza

Nthawi zina odwala amadandaula kuti mankhwalawa sawathandiza, ndiye kuti, sagwirizana ndi ntchito yake yayikulu - yotulutsa shuga. Izi zitha kuchitika pazifukwa zingapo. Pansipa ndalemba zifukwa zomwe metformin singathandizire.

• Metformin sinatchulidwepo chizindikiro
• Osakwanira mlingo
• Chithandizo Cha Mankhwala
• Kulephera kudya mukamamwa metformin
• Munthu aliyense

Nthawi zina zimakhala zokwanira kukonza zolakwika ndikuchepetsa shuga sizingakudikirire.

Pa izi ndikufuna kumaliza nkhani yanga. Lembetsani ku zosintha za blog kuti mumve zodalirika komanso zofunikira zokhudzana ndi matenda ashuga ndi zina zambiri. Dinani mabatani ochezera. ma network ngati mumakonda nkhani ndikuwona posachedwa!

Ndi chisangalalo ndi chisamaliro, endocrinologist Lebedeva Dilyara Ilgizovna

Malangizo a Diabeteson MV ogwiritsira ntchito

Momwe mungatenge Metformin pakuchepetsa thupi: ndemanga ndi zotsatira

Ogasiti 16, 2016 2256

Mwa mapiritsi ambiri azakudya, Metformin imatha kusiyanitsidwa. Chida ichi, pogwiritsa ntchito pafupipafupi, chimatha kuchepetsa kwambiri thupi.

Metformin imawonetsedwa kwa odwala omwe ali ndi matenda ashuga, koma anthu onenepa kwambiri amatha kuchepa thupi pomwa mankhwalawa.

Kufotokozera zamankhwala ndi mawonekedwe akumasulidwa

Mankhwala Metformin amapezeka mwa mawonekedwe a mapiritsi a pakamwa. Mapaketi ali ndi mapiritsi 30, 50, 60, 120, zonse zimatengera dziko lakapangidwe.

Zomwe zimagwiritsa ntchito mankhwalawa ndi metformin. Mankhwala zochita zam'mapiritsi ndi hypoglycemic.

Zochita za Metformin pa thupi:

1. Zakudya zomanga thupi zimakonzedwa mwachangu, zomwe zimapangitsa kuchepetsa thupi,
2. Kuchulukitsa kuchuluka kwa oxidation wamafuta acids,
3. Imachepetsa kuyamwa kwamatumbo,
4. Sizimathandizira kupanga insulini, yomwe imachepetsa kumverera kwanjala,
5. Amachepetsa shuga.

Mwachidule, Metformin imatsitsa kuchuluka kwa shuga m'thupi, zomwe zimapangitsa kuti muchepetse thupi. Mafani a maswiti amalipira zomwe amakonda pakukonda ndi kuchuluka kwa thupi, zomwe zingapewe mothandizidwa ndi mankhwala a Metformin.

Komabe, musanamwe mapiritsi, ndikofunikira kuti muphunzire mosamala zonse za mankhwalawa.

Ndizotheka kuchepetsa kulemera ndi Metformin pokhapokha ngati insulin yokwanira ipangidwa m'thupi. Kugwiritsa ntchito shuga sikungachedwetse kuchuluka kwa mafuta m'magazi, chifukwa cha kuchuluka kwa shuga ndi chiwindi mukamamwa mankhwalawa.

Malamulo otenga Metformin kuti muchepetse kunenepa

Ndiye, momwe mungatenge Metformin kuti muchepetse kunenepa? Kuti zotsatira za kumwa mankhwalawa zikhale zabwino, komanso mapiritsiwo palibe vuto, muyenera kutsatira malangizo a madokotala.

Simungathe kumwa mapiritsiwa kwa masiku opitilira 22, ndipo mlingo wa tsiku ndi tsiku sayenera kupitirira 1500 mg.

Malamulo owonjezerawa kutenga Metformin, kutsatira zomwe zingapangitse kuti muchepetse kuwonda:

• Mukamamwa mapiritsiwa, kuchita masewera olimbitsa thupi ndikofunikira,
• Maziko azakudya ayenera kukhala zopepuka komanso zopepuka m'mimba,
• Imwani madzi ambiri
• Dzichepetsani pakudya.

Aliyense amadziwa zinthu zomwe zimalimbikitsa kulemera msanga. Mafuta ndi pasitala, mpunga, mbatata, nyama yamafuta, mpunga ndi mowa ziyenera kukhala zochepa monga momwe mungathere.

Dokotala iyemwini amapereka mtundu weniweni wa Metformin kwa wodwala aliyense payekhapayekha. Anthu omwe si onenepa kwambiri, koma amakonda kunenepa kwambiri, amatha kumwa mapiritsi okhala ndi 200 mg, ndipo katswiri wazonenepa amapatsa mpaka 1500 mg patsiku.

Ndizotheka kuchepetsa thupi mothandizidwa ndi Metformin, koma mulimonsemo muyenera kudzipatula pakudya. Mukamamwa mankhwalawa, kulemera kumachepa. Ziwerengero zakuchepera zimatha kufika 15 kg.

Tiyenera kukumbukira kuti simungathe kuchepetsa thupi kwakanthawi kochepa, izi ndizovuta zamthupi, motero makilogalamu 5-6 m'masiku 22 ndizotsatira zabwinobwino.

Contraindication

Monga mankhwala aliwonse, Metformin imakhala ndi zotsutsana zingapo kuti mugwiritse ntchito komanso mavuto. Muyenera kuphunzira nkhaniyi mosamala musanamwe mapiritsi.

Anthu omwe ali ndi zotsutsana ndi Metformin:

1. Amayi oyembekezera komanso oyembekezera
2. Ndi ngozi yoopsa kwambiri yam'madzi.
3. Kuvutika ndi matenda a impso, chiwindi, kupuma komanso mtima,
4. Mowa
5. Odwala omwe ali ndi matenda a shuga omwe ali ndi vuto lalikulu laukoma kapena makolo.

Musaiwale kuti thupi la aliyense ndiwopadera ndipo limatha kugwirira ntchito molakwika mankhwala osadziwika. Hypersensitivity pamapiritsi aliwonse angachitike mosayembekezereka, ndikofunikira kuganizira izi musanamwe mapiritsi osayang'aniridwa ndi adokotala.

Zotsatira zoyipa zimatha kukhala zofatsa koma osamvetsetsa kwa nthawi yayitali, koma nthawi zina vutoli limatenga nthawi yayitali ndipo limafunikira kufunsa dokotala. Pakachitika vuto loti thupi litenge mapiritsi, muyenera kusiya kumwa.

Zotsatira zoyipa za Metformin

• Kusanza ndi kusanza
• Kupweteka kwam'mimba komanso kutsegula m'mimba
• Kuchepa kapena kusowa kwa chakudya,
• Tizilombo tating'ono tambiri thupi,
• Kulawa kwazitsulo pakamwa
• Lactic acid chikomokere (chakupha ndi chosowa).

Chimodzi mwazomwe zimayambitsa zovuta kutengera Metformin chitha kuonedwa ngati kuphwanya malamulo a kumwa mapiritsi. Mlingo wowonjezera wa tsiku ndi tsiku wa mankhwala atha kubweretsanso mavuto ena.

Musanatenge Metformin, ndikofunikira kuuza adotolo za zovuta zonse zomwe zilipo, matenda osachiritsika komanso otupa pokambirana ndi adokotala. Kubisika kwa chidziwitso chofunikachi kumatha kubweretsa zotsatira zoyipa.

Mtengo wa Metformin ukhoza kukhala wosiyana. M'mafakitala mumapezeka mankhwala osokoneza bongo ku rubles 50-3000. Zosankha zamapiritsi a mankhwalawa. Dokotala adzalembera mankhwala omwe wodwala aliyense payekhapayekha, akuganizira thanzi lake ndi zina zake.

Misonyezo ya mankhwalawa imapezeka kulikonse, koma mtengo wawo umakhala wokwera. Zotsatira za analogues ndi Metformin ndizofanana, koma mtengo wake ndi wosiyana. Bwanji mulipire ndalama zambiri ngati mungathe kugula zotsika mtengo.

Ndemanga za anthu oonda

Mankhwalawa adandilamula ndi adotolo, chifukwa shuga wanga m'thupi mwanga adakulirakulira. Ndikufuna kunena kuti momwe zimatengera izi zidadabwitsa ine. Ndinayamba kumva bwino, koposa zonse, ndinali wonenepa kwambiri. Ndataya 5 kg ndipo ndine wokondwa kwambiri. Zimakhala zokhumudwitsa pang'ono kuti ndimakhala ndi vuto logaya chakudya nthawi zonse, koma ndingatani.

Angelina, wazaka 39

Atsikana, ndinayesetsa kumwa Metformin kuti muchepetse thupi. Kulemera kunakhala pafupifupi malo, ndipo kupweteka kwa mutu ndi mseru kunandikuta kwa nthawi yayitali. Sindinadye, mwina ndichifukwa chake sizinandithandizire.

Christina, wazaka 23

Anandiika kuchipatala. Ndinkamwa kwa mwezi umodzi ndipo sindinazindikire kuti ndataya 8 kg. Poyamba sindinamvetsetse zomwe zinachitika, kenako ndinawerenga. Mwinanso kudya kwanga kunakhudzanso, ndinakusintha, monga shuga inayamba kutuluka. Mwambiri, ndimakondwera ndi zotsatira zake.

Ndipo ndidayamba kumwa Metformin makamaka kuti ndichepetse thupi. Pambuyo pake, ndidaphunzira malingaliro onse pa intaneti. Ndakhala ndikumwa mapiritsi kwa masiku 20, ndikuphunzira masewera olimbitsa thupi komanso kudya zakudya zopanda zakudya, ndinataya makilogalamu 9 panthawiyi. Zachidziwikire pali zovuta, koma muyenera kuyesetsa kwambiri. Pakapita kanthawi ndibwereza maphunzirowo.

Ndayesa mapiritsi ambiri azakudya ndipo ndikuganiza kuti Metformin siinasinthe ndi ena onse. Ndinkamwa kwa pafupifupi mwezi umodzi ndipo sindinachepetse kwambiri thupi; Ndinkadya pafupipafupi komanso sindinkachita masewera olimbitsa thupi, mwina zinkandikhudza.