Mapiritsi a Atorvastatin mapiritsi
Tsambali limapereka mndandanda wazofanana zonse za Atorvastatin mu kapangidwe kake ndi chisonyezo chogwiritsidwa ntchito. Mndandanda wama analogi otsika mtengo, mutha kuyerekezeranso mitengo muma pharmacies.
- Analogue yotsika mtengo kwambiri ya atorvastatin:Roxer
- Analogue yotchuka kwambiri ya atorvastatin:Crestor
- Gulu la ATX: Atorvastatin
# | Mutu | Mtengo ku Russia | Mtengo ku Ukraine |
---|---|---|---|
1 | Roxer rosuvastatin Mndandanda wazowonetsera ndi njira yogwiritsira ntchito | 5 rub | 25 UAH |
2 | Analogue ya Simvastatin pakuwunikira komanso njira yogwiritsira ntchito | 7 rub | 35 UAH |
3 | Rosulip rosuvastatin Mndandanda wazowonetsera ndi njira yogwiritsira ntchito | 13 rub | 42 UAH |
4 | Rosistark rosuvastatin Mndandanda wazowonetsera ndi njira yogwiritsira ntchito | 13 rub | -- |
5 | Atorvastatin-Teva atorvastatin Kuwonetsa mu kapangidwe kake ndi chisonyezo | 15 rub | 24 UAH |
Mukamawerengera mtengo wake zotupa zotsika mtengo za atorvastatin mtengo wocheperako womwe umapezeka mumndandanda wamapulogalamu omwe amaperekedwa ndi ma pharmacies adaganiziridwa
# | Mutu | Mtengo ku Russia | Mtengo ku Ukraine |
---|---|---|---|
1 | Crestor rosuvastatin Mndandanda wazowonetsera ndi njira yogwiritsira ntchito | 29 rub | 60 UAH |
2 | Roxer rosuvastatin Mndandanda wazowonetsera ndi njira yogwiritsira ntchito | 5 rub | 25 UAH |
3 | Liprimar atorvastatin Kuwonetsa mu kapangidwe kake ndi chisonyezo | 54 rub | 57 UAH |
4 | Romazik rosuvastatin Mndandanda wazowonetsera ndi njira yogwiritsira ntchito | -- | 93 UAH |
5 | Akorta calcium wa rosuvastatin Mndandanda wazowonetsera ndi njira yogwiritsira ntchito | 249 rub | 480 UAH |
Popeza mndandanda wamankhwala osokoneza bongo kutengera manambala a mankhwala omwe apemphedwa kwambiri
Analogs popanga ndi chisonyezo chogwiritsidwa ntchito
Mutu | Mtengo ku Russia | Mtengo ku Ukraine |
---|---|---|
Amvastan | -- | 56 UAH |
Atorvacor | -- | 31 UAH |
Atoris | 34 rub | 7 UAH |
Vasocline | -- | 57 UAH |
Livostor atorvastatin | -- | 26 UAH |
Liprimar atorvastatin | 54 rub | 57 UAH |
Thorvacard | 26 rub | 45 UAH |
Tulip Atorvastatin | 21 rub | 119 UAH |
Limistin Atorvastatin | -- | 82 UAH |
Lipodemin Atorvastatin | -- | 76 UAH |
Litorva atorvastatin | -- | -- |
Pleostin atorvastatin | -- | -- |
Tolevas atorvastatin | -- | 106 UAH |
Torvazin Atorvastatin | -- | -- |
Torzax atorvastatin | -- | 60 UAH |
Etset atorvastatin | -- | 61 UAH |
Aztor | -- | -- |
Astin Atorvastatin | 89 rub | 89 UAH |
Atocor | -- | 43 UAH |
Atorvasterol | -- | 55 UAH |
Atotex | -- | 128 UAH |
Novostat | 222 rub | -- |
Atorvastatin-Teva Atorvastatin | 15 rub | 24 UAH |
Atorvastatin Alsi Atorvastatin | -- | -- |
Lipromak-LF atorvastatin | -- | -- |
Vazator atorvastatin | 23 rub | -- |
Atorem atorvastatin | -- | 61 UAH |
Vasoklin-Darnitsa atorvastatin | -- | 56 UAH |
Mndandanda womwe uli pamwambapa wa analogies ya mankhwala, omwe akuwonetsa atorvastatin amalowa, ndizabwino kwambiri chifukwa zimakhala ndi zinthu zomwe zimagwirizana ndipo zimagwirana molingana ndi chisonyezo chogwiritsidwa ntchito
Analogs mwa chisonyezo ndi njira yogwiritsira ntchito
Mutu | Mtengo ku Russia | Mtengo ku Ukraine |
---|---|---|
Vabadin 10 mg simvastatin | -- | -- |
Vabadin 20 mg simvastatin | -- | -- |
Vabadin 40 mg simvastatin | -- | -- |
Vasilip simvastatin | 31 rub | 32 UAH |
Zokor simvastatin | 106 rub | 4 UAH |
Zokor Forte simvastatin | 206 rub | 15 UAH |
Simvatin simvastatin | -- | 73 UAH |
Vabadin | -- | 30 UAH |
Simvastatin | 7 rub | 35 UAH |
Vasostat-Health simvastatin | -- | 17 UAH |
Vasta simvastatin | -- | -- |
Kardak simvastatin | -- | 77 UAH |
Simvakor-Darnitsa simvastatin | -- | -- |
Simvastatin-zentiva simvastatin | 229 rub | 84 UAH |
Simstat simvastatin | -- | -- |
Alleste | -- | 38 UAH |
Zosta | -- | -- |
Lovastatin lovastatin | 52 rub | 33 UAH |
Ufulu wa anthu pravastatin | -- | -- |
Leskol | 2586 rub | 400 UAH |
Leskol Forte | 2673 rub | 2144 UAH |
Leskol XL fluvastatin | -- | 400 UAH |
Crestor rosuvastatin | 29 rub | 60 UAH |
Mertenil rosuvastatin | 179 rub | 77 UAH |
Klivas rosuvastatin | -- | 2 UAH |
Sinkhaninso rosuvastatin | -- | 143 UAH |
Rosart Rosuvastatin | 47 ma rub | 29 UAH |
Rosuvastatin Rosator | -- | 79 UAH |
Rosuvastatin Krka rosuvastatin | -- | -- |
Rosuvastatin Sandoz Rosuvastatin | -- | 76 UAH |
Rosuvastatin-Teva Rosuvastatin | -- | 30 UAH |
Rosucard Rosuvastatin | 20 rub | 54 UAH |
Rosulip Rosuvastatin | 13 rub | 42 UAH |
Rosusta Rosuvastatin | -- | 137 UAH |
Roxera rosuvastatin | 5 rub | 25 UAH |
Romazik rosuvastatin | -- | 93 UAH |
Romestine rosuvastatin | -- | 89 UAH |
Rosucor rosuvastatin | -- | -- |
Fastrong rosuvastatin | -- | -- |
Acorta Rosuvastatin Kalcium | 249 rub | 480 UAH |
Tevastor-Teva | 383 rub | -- |
Rosistark rosuvastatin | 13 rub | -- |
Suvardio rosuvastatin | 19 rub | -- |
Redistatin Rosuvastatin | -- | 88 UAH |
Rustor rosuvastatin | -- | -- |
Livazo pitavastatin | 173 rub | 34 UAH |
Kuphatikizika kosiyanasiyana, kungagwirizane mukuwonetsa ndikugwiritsa ntchito njira
Mutu | Mtengo ku Russia | Mtengo ku Ukraine |
---|---|---|
Lopid Gemfibrozil | -- | 780 UAH |
Lipofen cf fenofibrate | -- | 129 UAH |
Tricor 145 mg fenofibrate | 942 rub | -- |
Trilipix Fenofibrate | -- | -- |
Pms-cholestyramine lalanje lalanje lonunkhira bwino wa colestyramine | -- | 674 UAH |
Dzungu Mbewu Mafuta | 109 rub | 14 UAH |
Ravisol Periwinkle yaying'ono, Hawthorn, clover clover, chestnut ya Horse, White mistletoe, Japan Sofora, Horsetail | -- | 29 UAH |
Mafuta a nsomba a Sisode | -- | -- |
Kuphatikizika kwa Vitrum Cardio kwa zinthu zambiri zogwira ntchito | 1137 rub | 74 UAH |
Kuphatikizika kwa Omacor pazinthu zambiri zogwira ntchito | 1320 rub | 528 UAH |
Mafuta a nsomba yamafuta | 25 rub | 4 UAH |
Kuphatikiza kwa Epadol-Neo pazinthu zambiri zogwira ntchito | -- | 125 UAH |
Ezetrol ezetimibe | 1208 rub | 1250 UAH |
Repata Evolokumab | 14 500 rub | UAH 26381 |
Alirocoumab wamtengo wapatali | -- | 28415 UAH |
Kodi mungapeze bwanji analogue yotsika mtengo ya mankhwala okwera mtengo?
Kuti mupeze chiwonetsero chotsika mtengo cha mankhwala, chofananira kapena chofanana, choyambirira timalimbikitsa kulabadira kapangidwe kake, zomwe ndi zinthu zomwezo zomwe zikugwira komanso zomwe zikugwiritsidwa ntchito. Zomwe zimagwiritsidwanso mosiyanasiyana ndi mankhwalawa zimawonetsa kuti mankhwalawo ndi ofanana ndi mankhwalawo, monga mankhwala ena kapena mitundu ina. Komabe, musaiwale za zovuta zomwe zimagwiritsidwa ntchito ndi mankhwala ofanana, omwe angakhudze chitetezo ndi kugwiranso ntchito. Musaiwale za malangizo a madotolo, kudzipereka nokha kungawononge thanzi lanu, chifukwa chake onani dokotala wanu musanagwiritse ntchito mankhwala.
Zotsatira za pharmacological
Atorvastatin ndi wothandizira wa hypolipidemic kuchokera pagulu la ma statins. Malinga ndi lingaliro la kupikisana kwa mpikisano, molekyulu ya statin imamangiriza gawo ilo la coenzyme A receptor komwe HMG-CoA reductase ikalumikizidwa. Gawo lina la molekyu ya statin imalepheretsa kusintha kwa hydroxymethylglutarate kukhala mevalonate, wapakatikati mwa kapangidwe ka mamolekyulu a cholesterol. Kuletsa kwa ntchito ya HMG-CoA reductase kumabweretsa zotsatizana zotsatizana, zomwe zimapangitsa kutsika kwa zinthu zamafuta a cholesterol komanso kuwonjezereka kwa ntchito ya LDL receptors ndipo, motero, inapititsa katemera wa LDL cholesterol (Xc).
Main hypercholesterolemia ndi zakudya mankhwala kulephera, kuphatikiza hypercholesterolemia ndi hypertriglyceridemia, heterozygous ndi homozygous achibale hypercholesterolemia ndi zakudya mankhwala kulephera.
Contraindication
Matenda a chiwindi mu gawo logwira, kuwonjezeka kwa ntchito za seramu transaminases zoposa katatu nthawi yosadziwika, mimba, mkaka wa m'mawere (kuyamwitsa), ndikuwonjezera chidwi cha atorvastatin. Amayi azaka zakubadwa omwe sagwiritsa ntchito njira zodalirika zolerera. Atorvastatin imaphatikizidwa mu mimba ndi mkaka wa m'mawere (yoyamwitsa).
Mimba komanso kuyamwa
Atorvastatin ndi contraindicated pa mimba ndi mkaka wa m`mawere (yoyamwitsa).
Sizikudziwika ngati atorvastatin amachotsedwa mkaka wa m'mawere. Popeza kuthekera kwa zovuta mu makanda, ngati kuli kotheka, kugwiritsa ntchito mankhwalawa panthawi yoyamwa kuyenera kuganizira kuthetsa kuyamwitsa.
Amayi a msinkhu wobereka ayenera kugwiritsa ntchito njira zokwanira zolerera panthawi ya chithandizo. Atorvastatin itha kutumizidwa kwa azimayi azaka zakubadwa pokhapokha ngati mwayi wokhala wochotsa umakhala wotsika kwambiri, ndipo wodwalayo akudziwitsidwa za chiopsezo chamankhwala omwe mwana angafunse.
Malangizo apadera
Asanachitike komanso atagwiritsidwa ntchito ndi Atorvastatin, makamaka ndi mawonekedwe a kuwonongeka kwa chiwindi, ndikofunikira kuyang'anira zizindikiro za chiwindi. Ndi kuwonjezeka kwa ma transaminase, ntchito zawo ziyenera kuyang'aniridwa mpaka zachilengedwe. Ngati zochitika za AST kapena ALT, zopitilira katatu kuposa zabwinobwino, zimapitirira, kuchepetsa kumwa kapena kusiya kwa Atorvastatin ndikulimbikitsidwa.
Piritsi limodzi lili:
Chithandizo: atorvastatin calcium calcium,
Othandizira: calcium carbonate, MCC, StarKap1500 (wowuma chimanga ndi wowuma kale), colloidal silicon dioxide (aerosil), talc, magnesium stearate, Opadry II (mndandanda 85) (mowa wa polyvinyl, macrogol, talc, titanium dioxide, ironide oxide, iron ironide).
Zotheka m'malo mwa atorvastatin
Anvistat (mapiritsi) → mawu ofanana: 24 Up
Analogue ndiyotsika mtengo kuchokera ku ma ruble 110.
Wopanga: ANTIVIRAL NPO ZAO (Russia)
Kutulutsa Mafomu:
- Tab. zokutira filimu, 40 mg: 14 kapena 30 ma PC.
Analogue mtheradi wa Atorvastatin, wokhala ndi mndandanda womwewo wa zisonyezo, contraindication ndi zoyipa. Kusiyana kokhako ndikuletsa chithandizo cha Anvistat cha odwala ochepera zaka 18.
Atorvastatin-Teva (mapiritsi) → mawu ofanana: 38 Pamwamba
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 7.
Njira yothandizira kupanga kampani ya Israeli ya mankhwala Teva, yomwe kapangidwe kake, momwe amagwirira ntchito, njira yogwiritsira ntchito ndi zidziwitso sizosiyana kwambiri ndi "mankhwala" apoyamba.
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 39.
Wopanga: Oxford (India)
Kutulutsa Mafomu:
- 20 mg mapiritsi, 30 ma PC.
Analogue ndi ntchito yomweyi yomwe sanaikidwe kwa odwala omwe ali ndi tsankho lactose. Sitikulimbikitsidwa kuchita mankhwalawa ndi Lipoford panthawi yamatenda omwe ali ndi matenda owopsa, komanso kugwiritsa ntchito mankhwalawa kwa odwala omwe ali ndi khunyu. Mosamala komanso moyang'aniridwa ndi dokotala, chithandizo cha Lipoford chikuyenera kuchitika mwa anthu omwe ali ndi vuto lalikulu kapena matenda am'matumbo.
Atomax (mapiritsi) → mawu ofanana: 10 Pamwamba
Analogue ndiokwera mtengo kwambiri kuchokera ma ruble 71.
Wopanga: Hetero Drags Limited (India)
Kutulutsa Mafomu:
- 20 mg mapiritsi, 30 ma PC.
Zophatikizika ndizomwe zimagwira ntchito, koma pamtengo pafupifupi katatu kuposa Atorvastatin. Pokomera Atomax, kuti mndandanda wazotsatira zoyambira kugwiritsa ntchito ndizochulukirapo kangapo poyerekeza ndi Atorvastatin. Chifukwa chake, kusakhudzidwa kotereku komwe kumachitika pakumwa mankhwala ndi Atorvastatin, monga kutopa kwambiri ndi kuchepa kwa chidwi, sikuwopseza odwala omwe akuchitiridwa ndi Atomax.
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 104.
Mankhwala omwe ali ndi mndandanda wokulirapo pang'ono wa contraindication. Chifukwa chake, Tulip sinafotokozeredwe ana osakwana zaka 18, odwala omwe ali ndi matenda oopsa, komanso kwa anthu omwe anachita opaleshoni yochepera masiku 30 apitawa.
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 219.
Mankhwalawa amachokera pazomwe zimagwira ntchito monga Atorvastatin. Mosiyana ndi izi, Novostat sangathe kugwiritsidwa ntchito pochiza odwala osakwana zaka 18. Ndikofunikanso kudziwa kuti analogue iyi imakhala ndi zotsutsana pang'ono: makamaka, sinafotokozeredwe odwala omwe ali ndi tsankho lactose, ndipo makamaka pazochitika kwambiri - odwala omwe ali ndi matenda osokoneza bongo.
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 250.
Analogue ndi chinthu chomwechi chomwe chili ku Atorvastatin. Ndi mndandanda womwewo wa zisonyezo ndi ma contraindication, ili ndi mndandanda wawung'ono pang'ono wosasangalatsa womwe ungachitike. Ndikofunikira kuti akazi adziwe kuti kupambana kwa njira zakulera zochokera ku ethinyl estradiol kapena norethindrone kumachepera pafupifupi 20% panthawi yamankhwala ndi Atoris, chifukwa chake ndibwino kugwiritsa ntchito njira zowonjezerapo popewa kutenga pakati.
Ndimavomereza Atoris, koma pazifukwa zina miyendo yake imapweteketsa ndikuyamba kupweteka, kugwada m'miyendo yake. Kodi Atoris ingasinthidwe bwanji ndipo imatenga nthawi yayitali bwanji?
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 321.
Anorvastatin analog, osagwiritsidwa ntchito pochiza odwala osakwana zaka 18. Zotsatira zoyipa za mankhwalawa zimangofanana, koma odwala omwe amathandizidwa ndi Torvacard chithandizo, kuwonjezeka kwa thupi kumadziwika kwambiri, komwe sikuwonetsedwa ndi chithandizo cha Atorvastin.
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 575.
Analogue mtheradi wa Atorvastatin wokhala ndi chinthu chomwechi m'munsi, wokhala ndi mndandanda wazofanana, zotsutsana ndi zoyipa. Mtengo wake umakhala wokwera mtengo kwambiri, motero, kuyimitsidwa ndikofunika pokhapokha ngati wina wagulitsa.
Atorvastatin ndi kufananizira kwake ku Rosuvastatin
Atorvastatin - Chimodzi mwazomwe amamwa mankhwala a Russian hyperlipidemic. Mtengo wake ndi wotsika - pafupifupi 65 ma ruble a mapiritsi 30 muyezo wocheperako (10 mg), womwe umangowonjezera kufunikira pakati pa odwala. Chidacho chimapangidwa ndi Teva, Ozone, Biocom ndi ena. Ndi gawo la gulu la ma statins a m'badwo waposachedwa, lomwe lili ndi chinthu chachikulu yogwira - atorvastatin.
Muzochita zamankhwala, ma statin ena awiri amagwiritsidwa ntchito - simvastatin, rosuvastatin.
Atorvastatin ndi Rosuvastatin zimagwirizana kwambiri - onse awiri otsika cholesterol, kusintha mkhalidwe wamakhoma amitsempha yamagazi ndi ma capillaries, ndikuchepetsa kukula kwa atherosulinosis.
Machitidwe a Atorvastatin
Pambuyo pakukonzekera pakamwa, mapiritsiwo amalumikizidwa ndi coenzyme A receptors m'malo omwe HMG-CoA reductase yaphatikizidwa, ndikutseka kupanga kwake. Enzyme iyi ilipo mu chiwindi ndipo imachita mwachindunji pakupanga cholesterol. Mofananamo, ntchito ya mankhwalawa imapita mbali ina - njira yosinthira mankhwala apakatikati kukhala cholesterol imalepheretsa. Zotsatira zake ndi izi:
- kutsika pamaso pa cholesterol m'maselo,
- kupititsa patsogolo kufalikira kwa cholesterol yomwe ilipo mwa ma lipoprotein ena owopsa kwambiri.
Ndi ma lipoproteins awa pamlingo wokwera omwe amachititsa kukula kwa atherosulinosis. Kumwa mankhwalawa kumathandiza kuchepetsa kuchepa kwa matenda. Mofananamo, cholesterol "yabwino" yapamwamba imachulukana. Imanyamula mafuta ochokera ku cholesterol plaques ndikuwathandizira kukonza mu chiwindi. Zizindikiro zimachepetsedwa, chiopsezo cha kufa kwamtima chimathandizidwanso. Zotsatira zina za mankhwalawa:
- kukonza kwa khoma la mtima,
- kukhathamiritsa kwa magazi,
- antioxidant.
Ma metabolites a mankhwalawa amakonzedwa mu chiwindi, kuchokera komwe amatsitsidwa mwachilengedwe ndi bile. Kusiyanitsa pakati pa Rosuvastatin ndikuti zotsalira zake zimasiya ndowe sizisintha.
Zizindikiro zogwiritsidwa ntchito
Zizindikiro za onse othandizira a hyperlipidemic ndi ofanana, palibe kusiyana pankhaniyi. Kutengera ndi dzina ndi chochita, chisonyezo chachikulu ndi cholesterol yokwezeka, yomwe imadziwika ndi magazi akusala.
Mankhwalawa amalimbikitsidwa ndi adotolo kuti awalandire pokhapokha ngati pali zotsatira kuchokera ku "mafuta omwe amawotcha"
Atorvastitin imagwiritsidwa ntchito kwambiri popewa zovuta za atherosulinosis zomwe zimachitika popanda chithandizo cha matenda. Izi zimaphatikizapo thrombosis, stroko, mtima. Izi zonsezi zimachitika chifukwa chakulekanitsidwa kwa mapepala ndi kufalikira kwa ziwiya zofunika mu ubongo kapena mumtima. Chizindikiro cha mankhwalawa ndi chofunikira kwambiri mu chibadwa cha hyperlipidemia, chomwe chimavuta kusintha ndi mankhwala ena. Ma pathologies otsatirawa akuphatikizidwa m'gululi:
- hypercholesterolemia yoyamba,
- hypertriglyceridemia,
Komanso, mankhwalawa amayenera kuperekedwa pambuyo poti adwala matenda a mtima, kupewa matenda obwera chifukwa cha matenda oopsa. Ndi kusankha koyenera kwa mankhwalawa, mankhwala opangira mankhwala amatha kumwedwa ndi ana ndi akulu, okalamba.
Malangizo ogwiritsira ntchito
Kuchita mankhwala sikubweretsa kufunika kochotsa zakudya.Ndikofunikira nthawi yomweyo kuchepetsa kudya zamafuta akunja kuchokera kunja, komwe kumatheka ndi kuwonjezera kuchuluka kwa zakudya zamasamba muzakudya.
Mlingo wa mankhwalawa umayikidwa mosiyanasiyana payekhapayekha, zimatengera mlingo wa cholesterol, nthawi ndi mtundu wa matenda, kupezeka kwa cholowa. Munthawi ya mankhwala, mlingo umasinthidwa, chifukwa cha zomwe amamwa mankhwalawo. Malamulo ovomerezeka ndi awa:
- koyamba mlingo - 10 mg
- phwando limachitika kamodzi patsiku,
Atorvastatin silingatengedwe nthawi yomweyo ndi chakudya, mayamwidwe ake amachepetsedwa. Kusiyana kwake ndi Rosuvastatin ndikuti kudya kwotsirizira sikumadalira chakudya. Izi zitha kuwoneka zabwinoko komanso zosavuta kwa odwala ena. Pazonse, mankhwalawa omwe amafunsidwa ndi 10% osagwira kuposa rosuvastatin, omwe angatengedwe pang'onopang'ono.
Zotsatira zoyipa ndi zoletsa
Mankhwala ndi contraindicated mu kwambiri chiwindi matenda, chiwindi kulephera. Komanso, phwando liyeneranso kuikidwa posachedwa chifukwa cha matenda oopsa a kutupa, kukulira kwa mapangidwe a kufooka ndi chotupa cha ziwalo.
Sizoletsedwa kutenga atorvastatin ndi kuchuluka kwa AST ndi ALT ndi katatu popanda kutsimikizira zifukwa zake.
Mankhwalawa sanalembedwe pa nthawi yoyembekezera, kuyamwa, ndi hypersensitivity kwa yogwira mankhwala. Pa nthawi ya chithandizo, ndikofunikira kuwunika njira zakulera za amayi omwe ali ndi zaka zakubala.
Zotsatira zoyipa sizachilendo kusiyana ndi kugwiritsa ntchito simvastatin, kotero chomaliza monga cholowa popanda kuvomerezedwa ndi dokotala sichoyenera kumwa. Zina mwazinthu zosasangalatsa zomwe zalembedwa:
- kutsegula m'mimba
- kupweteka m'mimba
- kupweteka m'chiwindi
Nthawi zina, kupweteka mutu, kusowa tulo, kuchepa kwamapulatifomu, kuwonongeka kwa potency (osapitirira 3-4% ya odwala) kumadziwika. Anthu ambiri alibe zoterezi, chithandizo chimachitika kwa zaka zingapo popanda zotsatira. Mwa anthu opitilira zaka 70 ndi odwala matenda ashuga, nthawi zina, kuwonongeka kwamisempha kumawonedwa.
Zofananira zina za atorvastatin
Pali mitundu ingapo yachilendo ndi yofanizira yofanana ndi yogwira ntchito yomweyo. Sizipanga nzeru kuyang'ana mankhwala otsika mtengo - Atorvastatin ali ndi mtengo wotsika kwambiri pakati pa zophatikizira zomwe zimagwira. Mankhwala ochokera kunja ndiokwera mtengo kwambiri. Otsatirawa ndi fanizo la atorvastatin m'mawu ake:
Mankhwala | Chiwerengero cha mapiritsi / mlingo | Mtengo, ma ruble |
Tulip | 30/10 mg | 280 |
Thorvacard | 30/10 mg | 310 |
Atoris | 30/10 mg | 420 |
Liprimar | 30/10 mg | 780 |
Caduette ndi amlodipine | 30/10 mg | 1120 |
Mtengo wa phukusi lofanana la Rosuvastatin ndiwokwera kwambiri - ma ruble 260. Ndikosatheka kubwezeretsa mankhwala popanda kusintha kwa mankhwalawa komanso osagwiritsa ntchito mankhwala, chifukwa Rosustastatin nthawi zambiri amagwiritsidwa ntchito pazovuta zina za hyperlipidemia. Pa chithandizo ndi mankhwala aliwonse, ndikofunikira kuwunikira magwiridwe antchito a chiwindi sampuli iliyonse pakapita miyezi itatu.
Mlingo ndi makonzedwe
Asanaikidwe ndi Atorvastatin, wodwalayo ayenera kulimbikitsa zakudya zochepetsa lipid, zomwe ayenera kupitiriza kuzitsatira panthawi yonse ya chithandizo.
Mlingo woyambirira ndi pafupifupi 10 mg / tsiku. Mlingo umasiyana 10 mpaka 80 mg / tsiku.
Mankhwala amatha kumwa nthawi iliyonse masana ndi chakudya kapena osasamala nthawi yakudya. Mlingo umasankhidwa poganizira milingo yoyambirira ya cholesterol / LDL, cholinga cha mankhwala ndi zotsatira zake. Kumayambiriro kwa mankhwalawa komanso / kapena pakuwonjezeka kwa mlingo wa Atorvastatin, ndikofunikira kuyang'anira kuchuluka kwa plasma lipid masabata onse a 2-2 ndikusintha mlingo.
Kuti muwonetsetse Mlingo wa mankhwalawa omwe amaperekedwa pansipa, Atorvastatin angagwiritsidwe ntchito mwanjira ina ya mlingo: mapiritsi okhala ndi filimu, 10 mg ndi 20 mg. Mlingo wapamwamba tsiku lililonse wa mankhwala ndi 80 mg.
Ndi munthawi yomweyo kugwiritsa ntchito cyclosporine, tsiku lililonse mlingo wa atorvastatin sayenera upambana 10 mg.
Hypercholesterolemia yoyamba ndi hyperlipidemia yosakanikirana. Nthawi zambiri, mlingo wa 10 mg wa Atorvastatin kamodzi pa tsiku ndi wokwanira. Chithandizo chachikulu chamankhwala chimawonedwa pakatha masabata awiri, ndipo chofunikira kwambiri pochizira chimawonedwa pakatha milungu 4. Ndi chithandizo cha nthawi yayitali, izi zimapitirira.
Magulu apadera a odwala
Matenda aimpso. Kugwiritsa ntchito kwa odwala omwe ali ndi vuto la impso ndi matenda a impso sikukhudza kuchuluka kwa Atorvastatin m'magazi am'magazi kapena kuchepa kwa cholesterol / LDL akagwiritsidwa ntchito, chifukwa chake, kusintha kwa mankhwalawa sikofunikira.
Kuwonongeka kwa chiwindi. Ndi kulephera kwa chiwindi, mlingo uyenera kuchepetsedwa.
Odwala okalamba. Mukamagwiritsa ntchito mankhwalawa odwala okalamba, panalibe kusiyana pakukhwimitsa chitetezo, kugwira ntchito kapena kukwaniritsa zolinga za lipid-kuchepetsa mankhwala poyerekeza ndi anthu ambiri.
Zotsatira zoyipa
Kuchokera ku dongosolo lamanjenje: kusowa tulo, chizungulire, kupweteka mutu, kusamba, kugona, kugona, kupweteka kwam'mimba, kupweteka kwa mtima, matendawa, kukomoka, nkhope, kukhumudwa.
Kuchokera pamalingaliro: amblyopia, ikulira m'makutu, kuwuma kwa conjunctiva, chisokonezo cha malo okhala, kutulutsa magazi mu retina, ugonthi, glaucoma, parosmia, kuchepera kwa kukoma, kupotoza kwa kukoma.
Kuchokera pamtima: kupweteka pachifuwa, palpitations, vasodilation zizindikiro, orthostatic hypotension, kuchuluka kwa magazi, phlebitis, arrhythmia, angina pectoris.
Kuchokera ku hemopoietic system: anemia, lymphadenopathy, thrombocytopenia.
Kuchokera pakapumidwe: bronchitis, rhinitis, chibayo, dyspnea, kuchulukitsa kwa mphumu ya bronchial, nosebleeds.
Kuchokera m'mimba: nseru, kutentha kwa mtima, kudzimbidwa kapena kutsegula m'mimba, kusokonezeka kwa m'mimba, kupweteka kwam'mimba, kutsika kapena kufalikira kwamkamwa, kupindika, dysphagia, kusanza, stomatitis, esophagitis, glossitis, zilonda zam'mimba komanso zam'minyewa zam'mimba. biliary colic, cheilitis, zilonda zam'mimba, kapamba, cholestatic jaundice, kuphwanya chiwindi ntchito, magazi amitsempha, melena, magazi m`kamwa, tenesmus.
Kuchokera ku minculoskeletal system: nyamakazi, miyendo kukokana, bursitis, tendosynovitis, myositis, myopathy, arthralgia, myalgia, rhabdomyolysis, torticollis, minofu hypertonicity, mgwirizano wophatikizika, kutupa kwa mafupa, tendonopathy (nthawi zina ndi kupindika kwa tendon).
Kuchokera ku genitourinary system: matenda a urogenital, edema
Zomwe Zimayambitsa Matenda a Mtima
Matenda a Coronary amakula pazifukwa zosiyanasiyana. Pali zinthu zomwe sizingasinthidwe - jenda, zaka, komanso cholowa. Koma pali zoopsa zomwe zimatha kusinthidwa kuti zilepheretse kukula kwa matenda.
Zoyenera kusintha ndizophatikiza:
- Kusuta - ma nicotine resins ndi oopsa kwambiri mthupi la munthu. Akalowa m'magazi kudzera paukobiri wa alveolar, amakhala pamitsempha, amalowa khoma, ndikuphatikizira khoma la cell, zomwe zimapangitsa kuti likang'ambike ndipo ma microcracks amapezeka. Mapulatifomu, omwe amatseka chilema, pomwe akuwunikira zinthu zomwe zikuwoneka bwino, amakonda kuvulala. Kenako lipids imalumikizidwa ndi malowa, pang'onopang'ono imadziunjikira ndikuchepetsa lumen. Chifukwa chake kuyamba kwa atherosclerosis, kumabweretsa kukula kwa matenda a mtima ndipo, pambuyo pake, kumayambitsa matenda obisika.
- Kunenepa kwambiri. Mafuta omwe amapezeka panthawi ya kuperewera kwa zakudya m'thupi amagawidwa mosalingana, choyamba kumangoyang'ana ziwalo. Chifukwa cha izi, ntchito yawo imasokonekera, mtima ndi ziwiya zazikulu zimavutika. Ndikofunikanso kudziwa kuti ndi kunenepa kwambiri, kuchuluka kwa lipoproteins yotsika kumachulukanso ndipo kuchuluka kwa lipoproteins kwapamwamba kumatsika, zomwe zimathandiza kuwonetsa matendawa.
- Hypodynamia - imayambitsa kufooka kwa minofu komwe sikogwirizana ndi kamvekedwe ka minyewa, kamene kamapangitsa kuti minyewa ichepe komanso kuchepa. Izi zimabweretsa zolakwika m'makoma amitsempha,
- Kuledzera - kumabweretsa kuledzera kwathunthu kwa thupi, kumakhudza mitsempha yamagazi ndikuwononga hepatocytes. Imakhudzanso vena cava, chotengera cha hepatic. Poizoni amadziunjikira khoma la chotengera, chimacheperachepera.
Mothandizidwa ndi izi pachiwopsezo cha anthu, komanso kupsinjika, kutopa kwakanthawi ndi matenda ena okhudzana ndi matenda, atherosulinosis imayamba - kulumikizana koyambirira kwa matenda othandizira.
Ndi izo, zolembera zimakhazikika pa makoma amitsempha yamagazi kuchokera ku cholesterol, yomwe mkati mwa kukula imalepheretsa kuthamanga kwa magazi.
Njira zakuchiritsa kwa atherosulinosis
Matendawa ndivuto lenileni, chifukwa munthu aliyense wachitatu amakula pambuyo pa zaka 50. Ichi ndichifukwa chake makampani onse azachipatala amaika kutsogolo kukhazikitsidwa kwa mankhwala ochiritsa atherosulinosis.
Komabe, njira yoyambirira yodzitetezera imagwiritsidwa ntchito makamaka. Kuwonjezeka kwa zochitika zolimbitsa thupi, osachepera ola limodzi patsiku (ndipo izi zitha kukhala zowongolera kapena zinthu zotentha, kapena kuyenda mwachangu kapena kuyenda mu mpweya watsopano), kumachepetsa kukula kwa atherosclerosis ndi 40%. Mukasintha zakudya ndikuwonjezera, kuwonjezera pa nyama, chimanga, zipatso ndi ndiwo zamasamba, ndiye kuti chiwopsezocho chichepa ndi 10% ina. Kusiya kusuta kumatenga gawo limodzi mwa magawo khumi ali pachiwopsezo.
Ngati njira zonsezi sizinathandize, mankhwalawa amaphatikizidwa munthawi yamankhwala. Mankhwala ochepetsa lipid amakono okhala ndi zotsatira zotsimikiziridwa adapangidwa zaka makumi atatu zokha zapitazo, izi zisanachitike, mankhwalawa amachitidwa ndi mahomoni ogonana achikazi - estrogens, nicotinic acid, othandizira mafuta acids. Adawonetsa zotsatira zokhumudwitsa - kufa kwa matenda a coronary kudakulirakulira.
Mu 1985, kampani yopanga mankhwala ku Germany, Pfizer, idasankha dzina latsopano - Atorvastatin. Kutengera ndi ichi, ndi kuwonjezera pazinthu zothandizira, mankhwala oyamba omwe ali ndi anticholesterolemic kwenikweni, Liprimar, anapangidwa. Adatseketsa enzyme HMG-CoA reductase, kusokoneza limagwirira a cholesterol synthesis mu chiwindi pa gawo la cholesterol precursor - mevalonate.
Kafukufuku wosasinthika, wakhungu adavumbulutsa zotsatira zamatenda a atorvastatin. Zotsatira zake, dontho la miloprotein yotsika mpaka 40% lapezeka.
Ngati odwala ali ochepa matenda oopsa, Atorvastatin muyezo wa mamiligalamu 5 mpaka 20 kwa zaka zitatu za monotherapy amachepetsa chiopsezo chokhala ndi infracation ya myocardial ndi 35%.
Kusiyana pakati pa zoyambira ndi zotuluka
Liprimar si mankhwala okhawo omwe amapezeka ku ma statins angapo, ngakhale, mosakayikira, malinga ndi maphunziro azachipatala, ndiabwino kwambiri. Pakati pa 1985 mpaka 2005, pomwe kuteteza patent kunali kogwira, anali yekha. Koma kenako kachitidwe kake kanayamba kupezeka pagulu, ndipo ma fanizo anayamba kuwonekera, otchedwa magenic. Onsewa ali ndi formula wamba ndi Atorvastatin, ndipo, mwaluso, ayenera kukhala ndi njira yofanana yochizira.
Komabe, chifukwa cha kukhulupirika kwa malamulo a mayiko ambiri pamavuto azachipatala, ali ndi mawonekedwe okha ndi oyambirirawo. Malinga ndi zolembedwa zomwe ambiri amavomereza, kuti mupange dzina latsopano lazamalonda, muyenera kungopereka chikalata chofanana ndi mankhwala ku komisolo. Koma vuto ndi loti njira yopezera zinthuzo ikhoza kukhala yosavuta, ndipo izi zitsogolera kusintha kwa malo. Izi zikutanthauza kuti achire azitha kuchepa, kapena akhale ochepa.
Pakadali pano, ma liprimar opanga ma Liprimar ali ndi mayina opitilira 30, onse ali ndi atorvastatin ngati chinthu chogwira ntchito. Otchuka kwambiri a iwo ndi Atorvastatin (wopangidwa ku Russia) ndi Atoris (wopanga - Slovenia). Onsewa amagulitsa bwino mumafakitale, koma pali zosiyana pakati pawo.
Kusiyana koyamba kumatha kuwoneka kale mu mankhwala - awa ndi mtengo wa 10 mg:
- Liprimar - zidutswa zana - rubles 1800,
- Atoris - 90 zidutswa - 615 rubles,
- Atorvastatin - 90 zidutswa - 380 ma ruble.
Funso limabuka, bwanji mtengo uli wosiyana kwambiri ndi momwe Atorvastatin ingasinthidwe. Liprimar adachita kafukufuku wazachipatala kwathunthu, adalandira patent, ndipo zimatengera zinthu zambiri kuti apange ndikulengeza. Chifukwa chake, kampaniyo imayika mtengo wokwera kwambiri ngati malipiro a mtundu wodalirika, woyesedwa pazaka khumi zoyesedwa.
Atoris, wopangidwa ku Slovenia, adachita kafukufuku wazaka zitatu wazaka ziwiri, pomwe zidatsimikiziridwa kuti amatsitsa lipoprotein otsika pang'ono ndi 5% yochepera kuposa choyambirira, koma zotsatira zake zochizira sizikukayika ndipo zitha kugwiritsidwa ntchito ngati analogue ya Liprimar.
Atorvastatin wapanyumba sanadutsepo mayeso onse azachipatala, ndipo kufanana kwake ndi mankhwala komwe kumatsimikiziridwa, kotero ndikotsika mtengo kwambiri. Komabe, momwe zimakhudzira thupi sizikudziwika mwatsatanetsatane, zimachita kusankha, kutanthauza kuti, zitha kuthandiza munthu wina ndikuvulaza wina. Imagulidwa ndi anthu omwe sangathe kugula mankhwala ochokera kunja.
Zotsatira zamankhwala zimatha kuwunika pambuyo pa makonzedwe. Komabe, kuti akwaniritse izi, Liprimar imayenera kutengedwa m'milungu iwiri yokha, Atoris - atatu, ndi Atorvastatin m'maphunziro a miyezi iwiri. Izi zimatha kuyambitsa chiwindi.
Kuti izi zisachitike, tikulimbikitsanso kumwa mankhwala a hepatoprotectors motsatana.
Momwe mungaphatikizire ma statins?
Kuphatikiza pa zotumphukira za atorvastatin, palinso zinthu zina zogwira ntchito pamsika wogulitsa mankhwala zomwe zimagwiritsidwa ntchito ku atherossteosis. Izi ndi zotumphukira za losartan, angiotensin 2 inhibitor, mwachitsanzo, mankhwala a Lozap. Chochita chake chachikulu sicholinga chofuna kuthana ndi cholesterol ya LDL, koma pakuchepetsa kukakamira, kotero nthawi zambiri amagwiritsidwa ntchito limodzi ndi mabedi pakuphatikiza mankhwala. Komabe, Lozap imakhudza ma hepatocytes, chifukwa chake anthu omwe ali ndi vuto la chiwindi amalephera kukaonana ndi dokotala asanayambe chithandizo. Zotsatira zabwino zophatikiza ndi ma statins zimawonetsedwa ndi calcium blockers, mwachitsanzo, Amlodipine.
Pankhani ya kusagwirizana ndi Liprimar, ndikofunikira kugwiritsa ntchito analogues ndi zina mwa atorvastatin. Awa ndi rosuvastatin ndi simvastatin. Iwo, monga ma statins ena, onse amakhudza mulingo wa HMG-CoA reductase enzyme ndipo ali ndi magawo ofanana a pharmacodynamic.
Komabe, popanga kafukufuku zidapezeka kuti Rosuvastatin ali ndi nephrotoxicity, ndiye kuti, ikhoza kukhudza rerench parenchyma, ndikuwopseza kukula kwa aimpso.
Simvastatin imatsitsa mulingo wama lipoproteins otsika ndi 9% yochepera kuposa Liprimar, zomwe zimawonetsa kugwira kwake ntchito kotsika. Izi zikutanthauza kuti Liprimar adakhalabe mtsogoleri pamsika wogulitsa kuchokera ku gulu la ma statins, zomwe zimatsimikiziridwa osati ndi zotsatira za kafukufuku komanso zaka zambiri pozigwiritsa ntchito ndi madokotala pochiza matenda a atherossteosis, komanso ndi ndemanga zabwino za odwala.
Atorvastatin akufotokozedwa mu kanema munkhaniyi.
Zotsatira zamankhwala mankhwala Atorvastatin ndi analogies
gulu la odwala | matenda achire zotsatira |
---|---|
odwala akuluakulu popanda IHD matenda, koma pangozi: | chiopsezo chotengera ma pathologies amachepa: |
Nikotine ndi mowa | Mtima osakhazikika angina, |
Matenda oopsa | Myocardial infaration |
· Kutalika zaka | Matenda a ziwalo. |
Hypercholesterolemia, | |
· Pathology ya mtima mu banja. | |
odwala omwe ali ndi mtundu wa 2 matenda a shuga omwe alibe IHD, koma ali ndi zoopsa. | chiopsezo chotengera ma pathologies amachepa: |
Mankhwala osokoneza bongo a Nikotine | Myocardial infaration |
Retinopathy | Sitiroko. |
Matenda oopsa | |
Matenda a albuminuria. | |
odwala matenda a ischemic matenda a mtima | chiopsezo chocheperako: |
· Kukhazikika kwaina wosakhazikika, | |
Kukuchitika kwa infalction kopanda magazi. | |
· Kukula kwa zakupha ndi zopanda nkhawa. |
Zotsatira zoyipa
Mankhwala a gulu la statin ali ndi mndandanda waukulu wazotsatira zoyipa, chifukwa chake choyambirira cha mankhwala ndi mawonekedwe ake sicholinga chodzithandiza okha kuti azikhala ndi cholesterol yayikulu.
Zotsatira zoyipa za thupi zimasonyezedwanso chimodzimodzi ndi mankhwala achilendo akunja komanso zotsika mtengo, zotulutsidwa ku Russia.
Zotsatira zoyipa ndizambiri:
- Zilonda zapakhosi ndi m'mphuno,
- Matenda amtundu wa genitourinary system, komanso ngalande ya urethral,
- Ziwengo
- Pathology hyperglycemia,
- Mutu ndi chizungulire,
- Sinus magazi
- Kupumira, nseru
- Defecation matenda - kudzimbidwa, kapena kutsegula m'mimba, komanso kunyengerera,
- Minofu ndi kupweteka molumikizana komanso kukokana,
- Kuphatikizika kwa kutupa ndi kutupa
- Kuchepetsa thupi ndiodwala,
- Masomphenya amachepera ndipo tinnitus amawoneka
- Kusokonezeka kwa kugona ndi maloto olemera usiku
- Kuchuluka kwa mikono ndi miyendo,
- Pathology hyperesthesia,
- Amnesia osakhalitsa
- Hepatitis
- Zowawa mu peritoneum,
- Kutupa kwa nkhope ndi miyendo,
- Edincke's edema,
- Pathology myositis ndi myalgia,
- Myopathy ndi matenda a rhabdomyolysis,
- Kugwedezeka kwa anaphylactic.
Chingalowe m'malo ndi atorvastatin?
Mndandanda wa ma analogu ndi maulosi ofanana a mapiritsi a Atorvastatin omwe amapangidwa ndi makampani aku Russia ndipo ndiwotsika mtengo pamtengo:
dzina la mankhwala | mtengo muma ruble | machitidwe a anorvastatin analog |
---|---|---|
Atorvastatin Оbl | kuchokera ku 150.00 | lipid yotsitsa mankhwala yochepetsera zigawo za OH ndi LDL |
Wotsika Mtengo wa Atorvastatin - Anvistat | kuyambira 120,00 | mndandanda wabwino kwambiri wa mankhwalawa, womwe uli ndi mawonekedwe ofanana ndi Atorvastatin |
otsiriza mankhwala Novostat | kuyambira 320,00 | mankhwala ndi yogwira mankhwala atorvastatin: |
· Amatsitsa cholesterol index mu pulayimale yodziwika bwino komanso yodziwika bwino kwa cholesterolemia, | ||
Ndi matenda dysbetalipoproteinemia. | ||
Gwiritsani ntchito mankhwalawa kupewa matenda a m'magazi ndi matenda a mtima | ||
Mankhwala a Atomax | kuchokera 380,00 | mankhwalawa siwotsika mtengo koma wogwira ntchito pakuchepetsa cholesterol yochepa. Yogwira pophika atorvastatin |
mankhwala Atoris | kuyambira 320,00 | mankhwala ndi atorvastatin chachikulu cha zinthu amachepetsa OH ndi zigawo za LDL, VLDL, TG |
Analogi opanga akunja
dzina la mankhwala | mtengo muma ruble | machitidwe a anorvastatin analog |
---|---|---|
mankhwala Tulip | kuyambira 205,00 | lipid-kutsitsa kupanga Switzerland |
analog - Atorvastatin Teva | kuyambira 170,00 | analogue yabwino kwambiri yamankhwala, omwe amapangidwa ku Israeli |
Liprimar | kuchokera 700,00 | mankhwala omwe ali ndi mankhwala othandizira atorvastatin, opangidwa ku Germany ndipo ndi amodzi mwa mitengo yotchipa kwambiri. |
mankhwala Torvakard | kuchokera 430.00 | mankhwalawa si analogue wotsika mtengo, koma mphamvu yake yatsimikiziridwa. Wopezeka ku Czech Republic, chophatikizika ndi atorvastatin. |
Pomaliza
Mankhwala Atorvastatin ali ndi mitundu yambiri ya mitundu yaku Russia ndi mitundu yakunja yokhala ndi mitundu yosiyanasiyana yamitengo, kotero adotolo athe kusankha mankhwala ofunikira kwambiri pochiza hyperglycemia.
Koma musaiwale kuti mankhwala onse oyambira ndi mawonekedwe awo ayenera kumwedwa limodzi ndi zakudya komanso zolimbitsa thupi.
Ndikuyembekeza zaka 54: Ndinapezeka kuti anali ndi cholesterol yayikulu zaka 4 zapitazo. Poyamba ndinayesera kuti ndichepetse zakudya, koma kunenepa kwambiri sikunandilolere kubwezeretsanso cholesterol yanga. Dokotala adandiwuza kuti ndithandizidwe ndi atorvastatin.
Ndidamwa mankhwalawa kwa miyezi 10 ndipo ndidayamba kuwonetsa zoyipa m'misempha ndi m'mutu.
Ndidadziwitsa adotolo, ndipo adandipatsa analogue yaku Russia ya Novostat. Ndimamwa mankhwalawa kwa chaka chimodzi ndi miyezi 21, ndipo sindimva zoyipa zilizonse.
Dmitry zaka 60: Ndinayamba kuchitira matenda a atherosulinosis chaka chimodzi chatha ndikugwiritsa ntchito analogue yopanga kunja kwa Torvacard.
Patatha mwezi umodzi kumwa mapilogalamu adawonetsa kuchepa kwakukulu kwa cholesterol yoyipa, koma sindinathe.
Torvacard ndi mankhwala odula, ndipo sindinathe kutenga nthawi yayitali, ndinapempha adotolo kuti andibwezeretse ndi analogue yotsika mtengo kwa ine.
Lero ndimamwa mankhwala aku Israeli a Atorvastatin Teva, ndipo cholesterol yanga yakhala ikugwira bwino ntchito kwa miyezi iwiri tsopano. Kuchita bwino kwa ma statins sikudalira mtengo.
Njira ya ntchito, Mlingo
Zomwe zimachitika tsiku ndi tsiku zimayikidwa payekha, kutengera muyeso woyamba wa cholesterol. Imwani piritsi limodzi kamodzi patsiku, madzulo, mukatha kudya. Mlingo woyambirira wa 10 mg, wokhala ndi atherosulinosis, ungakulidwe mpaka 40 mg, pazokwanira - 80 mg. Zotsatira zake zimawonekera patatha masabata awiri atamwa mankhwalawo, zotsatira zake zazikulu - pambuyo pa mwezi umodzi. Ngati ndi kotheka, onjezani mlingo uliwonse pakatha milungu 6 iliyonse.
Cholinga chake chikakwaniritsidwa, wodwalayo amachepetsa mafuta m'thupi, mlingo umachepetsedwa, koma mankhwalawo pawokha sangathe. Mu 90% ya milandu, odwala hypercholesterolemia amakakamizidwa kutenga ma statins moyo wonse.
Malinga ndi kafukufukuyu, kugwiritsa ntchito atorvastatin mwa odwala omwe ali pachiwopsezo chotenga matenda a mtima (CHD) olola:
- kuchepetsa imfa ndi 13%,
- muchepetse pafupipafupi kukomoka kwa myocardial - mwa 21%, stroke - mwa 27%,
- kuchepetsa kuchuluka kwa maopareshoni kuti abwezeretse magazi m'mitsempha yomwe yakhudzidwa - ndi 21%.
Atorvastatin imalowa mwachangu m'magazi. Mu maola 1-2 okha, kugwiritsa ntchito mankhwalawa kumakhala kokwanira. Kutha kuletsa ntchito ya enzyme kumatha maola 20-30. Mankhwala amachotseredwa ndi chiwindi. Ndi matenda a chiwalo ichi, mankhwalawa amadziunjikira. Chifukwa chake, atorvastatin amalembedwa mosamala kwa odwala omwe ali ndi vuto la chiwindi.
Kuchita
Ndi makonzedwe omwewo munthawi imodzi ndimankhwala angapo, amatha kukulitsa zovuta zake. M'pofunika kupewa kucheza ndi atorvastatin:
- cyclosporin
- tipranavir ndi ritonavir,
- gemfibrozil,
- telaprevir.
Kuphatikiza kwa atorvastatin ndi mankhwala otsatirawa kumafuna kusintha kwa mlingo:
- lopinavir ndi ritonavir,
- madalin,
- niacin
- itraconazole,
- omeprazole
- ezetimibe
- digoxin
- colchicine
- nelfinavir
- diltiazem
- verapamil
- boceprivir.
Analogs Odziwika komanso Otetezeka
Zilonda zamankhwala - Mankhwala okhala ndi zosakaniza zomwe zimagwiritsidwa ntchito, Mlingo, koma ndi mayina osiyanasiyana azamalonda omwe amalembetsedwa ndi makampani opanga mankhwala.
Komanso, analogues imasiyana m'magawo azinthu zothandiza: zoteteza, kapangidwe ka chipolopolo, zomwe sizimakhudza ma pharmacological.
Atorvastatin ndi mayendedwe ake amapangidwa ndi makampani aku Russia ndi akunja. Mbiri yotsimikiziridwa, yabwino yamankhwala imasiyanitsidwa ndi makampani opanga mankhwala Pfizer, Krka, Zentiva, Teva, Lek, Northern Star, Vertex.
Chimodzi mwamagawo abwino kwambiri a Atorvastatin. Wopanga KRKA (Slovenia).
Hypolipidemic wothandizira wachitatu wama statins. Cholesterol chonse chimachepetsedwa ndikuchepetsa kuzungulira kwa LDL. Zotsatira zake zimadalira mlingo. Kukula kwakukulu, kuchuluka kwa ma sterol kumachepetsedwa. Dokotala yekha ndi amene amatha kuwerengera ndendende kuchuluka kwake, poganizira kuchuluka kwa magazi, zotsatira zoyenera, matenda omwe alipo.
Atoris akulimbikitsidwa kutsitsa cholesterol mwa odwala omwe ali ndi homozygous hyperlipidemia, omwe amalimbana ndi mankhwala opatsirana a lipid. Amalembedwanso hypercholesterolemia, dysbetalipoproteinemia.
Mankhwala amagwira ntchito ngati prophylactic omwe amalepheretsa kukula kwa mtima wamatenda, mtima. Itha kufotokozedwa ngati yachiwiri prophylaxis kwa anthu omwe akudwala matenda a mtima, kuti muchepetse chiopsezo cha kufa, kugunda kwa mtima, sitiroko.
Tengani piritsi limodzi / tsiku madzulo. Ngati ndi kotheka, onjezani mlingo uliwonse pakatha masabata anayi. Onetsetsani kuti mwayang'anira magawo amomwe ammwazi.
Atoris imalekeredwa bwino ndi thupi. Nthawi zina, zovuta zomwe zimachitika mu mantha zimatheka: mutu, kusowa tulo, chizungulire. Zizindikiro zimapita zokha, osafuna chithandizo chamankhwala. Koma adotolo ayenera kuwauza, mwina ili ndi vuto mu regimen. Mutha kuwasintha mwa kusintha mankhwalawo kapena kusintha mankhwalawo.
Chachikulu contraindication: pachimake chiwindi matenda. Chenjezo limaperekedwa kwa ana, achinyamata ochepera zaka 18. Zambiri kuchokera pa mayeso azachipatala pakuthandizira komanso chitetezo cha mankhwalawa sizokwanira.
Mankhwala oyamba opangidwa ndi PFIZER (Germany). Ndi kampaniyi yomwe idalandira chilolezo chotulutsa Atorvastatin. Wotsika mtengo kwambiri pamankhwala onse a analog, mtengo wake umachokera ku ma ruble 600.
Imakhala ndi chithandizo chokwanira kwambiri. Amapezeka m'matumba a mapiritsi 14 mpaka 100. Izi ndizothandiza kwa odwala omwe akungoyamba kumene kutenga ma statins. Kumayambiriro kwa chithandizo, phukusi laling'ono lingathe kugulidwa kuti liwunikenso zomwe zikuchitikazo, zomwe thupi limachita.
Tengani 1 pc. / Kamodzi patsiku, m'mawa, masana kapena madzulo, osasamala chakudya. Perekani kwa achikulire, achinyamata, ana opitirira zaka 10. Kugwiritsa ntchito mankhwala okalamba sikutanthauza kusintha kwa mlingo.
Liprimar imalekeredwa bwino. Zotsatira zoyipa ndizosowa, zimadutsa mwachangu. Kuthana ndi mankhwalawa kapena kukonza kuchuluka kwa tsiku lililonse sikufunika.
Wopanga BIOPHARM Pvt. Ltd (India). Zizindikiro zazikulu ndizofunikira, zosakanikirana za hypercholesterolemia, homozygous hyperlipidemia, kuwonjezera pa zakudya, masewera olimbitsa thupi.
Amasankhidwa mosamala kwa odwala omwe ali ndi vuto lochepa kapena kwa chiwindi. Popeza kuchotsedwa kwa atorvastatin kumachepetsedwa, ndikofunikira kuwongolera magawo amwazi a magazi.
Sizoletsedwa kumwa mankhwalawa chifukwa cha matenda oopsa a hepatitis. Contraindated mwa amayi apakati, amayi oyamwitsa, ana, achinyamata osakwana zaka 18. Kumwa mapiritsi kuyenera kuyimitsidwa miyezi iwiri isanakwane mimba yomwe yakonzekereratu.
Wopanga ZENTIVA (Czech Republic).
Gawani kuchepetsa kuchuluka kwambiri kwa cholesterol, matenda a mtima
Mankhwalawa angagwiritsidwe ntchito kuphatikiza mankhwalawa ndi michere, sequestrants ya bile acids. Mlingo - piritsi 1 / tsiku, nthawi iliyonse tsiku. The achire zotsatira kuonekera pambuyo 2 milungu. Ndi chithandizo chotenga nthawi yayitali, zotsatira zake zimakwaniritsidwa.
Pa mankhwala ndi mankhwala madandaulo a minofu ululu akuti. Kukhalapo kwa zizindikiro zotere kumafunika chisamaliro chamankhwala. Mungafunike mankhwala obwezeretsa.
Atorvastatin analogue kampani yopanga mankhwala SANDOZ (Slovenia).
Gawani kukonza kuchuluka kwa cholesterol yokwanira mwa odwala omwe ali ndi mitundu ina ya hypercholesterolemia. Pazoyambirira kupewa matenda amtima popanda chizindikiro cha matenda a mtima, okhala ndi chiopsezo chachikulu pakukula kwake (zaka zopitilira 50, matenda oshuga a shuga, siteji II-III, kuthamanga kwa HDL).
Mlingo wofanana: Piritsi limodzi / tsiku, mosasamala kanthu ndi chakudya.
Pafupipafupi, chizungulire komanso kusokonezeka kwa thupi kumatha kuonekera kuchokera ku dongosolo lamanjenje. Pa chithandizo, ndikofunikira kusiya ntchito yomwe ikukhudzana ndi kuchuluka kwa chidwi, kuyendetsa magalimoto.
Atorvastatin-Teva
Makampani opanga TEVA (Israel). Zinthu zotsika mtengo za Atorvastatin, zotsika mtengo kuchokera kuma ruble 200.
Perekani monga chida chachikulu pa matenda a hypercholesterolemia, atherosulinosis, kupewa matenda a mtima pambuyo pa opaleshoni kapena mtima.
Atorvastatin- OBL
Production FP Obolenskoe (Russia).
Hypolipidemic wothandizira wokhudzana ndi ma statins a m'badwo wa III. Perekani mankhwalawa pulayimale, yachiwiri hypercholesterolemia, komanso kuwonjezeka kwa serum thyroglobulin.
Mlingo wa 80 mg umaperekedwa mosamala mwa ana, achinyamata osaposa zaka 18, popeza magwiridwe antchito ndi chitetezo sichinakhazikitsidwe.
Mankhwalawa ndi kampani ya Atol (Russia). Gelatin wokutira makapisozi. Zomwe zili mkati ndizosakaniza ndi ufa woyera ndi granules.
Analog ya ku Russia ya mankhwala Atorvastatin mu makapisozi amasungunuka mwachangu ndikulowa mumtsempha wamagazi, koma izi sizikuwakhudza achire. Amalimbikitsa anthu omwe ali ndi zilonda zam'mimba, zilonda zam'mimba.
Mlingo wa tsiku ndi tsiku ndi 1 kapisozi, mlingo umayikidwa ndi dokotala payokha kwa wodwala aliyense.
Kutenga mankhwalawa contraindicated pa mimba, yoyamwitsa, ndi pachimake matenda a chiwindi. Gwiritsani ntchito mosamala odwala omwe amamwa mowa mopitirira muyeso.
Wopanga makampani opanga mankhwala Nizhpharm.
Perekani ngati chithandizo chachikulu cha hypercholesterolemia ya pulayimale kapena yachiwiri. Kuti muchite bwino, ndikofunikira kuphatikiza ndi chakudya chomwe chimachepetsa cholesterol yonse.
Tengani piritsi limodzi kamodzi / tsiku. Mlingo wofotokozedwa ndi dokotala. Kuchuluka kwa tsiku ndi tsiku kumatengera kusanthula kwachilengedwe kwamwazi, matenda omwe alipo.
Pali mwayi wina wamavuto obwera chifukwa cha musculoskeletal system: kukokana, kupweteka kwa minofu, mafupa. Komabe, sikuti nthawi zonse pali mgwirizano pakati pa Atomax ndi zotsatira zoyipa.
Wopanga Antiviral (Russia).
Mankhwala opanga a gulu la statin. Amachepetsa cholesterol mwa anthu omwe ali ndi vuto la mabanja. Amatchulidwa ngati prophylactic ya mtima mavuto. Ndikulimbikitsidwa kuti mutengeko pambuyo pa infilation, nthawi yothandizira kuti muchepetse ngozi yoti mubwererenso.
Kafukufuku wasonyeza kuti mukamagwiritsa ntchito Anvistat odwala okalamba, palibe kusiyana pakukwanitsa komanso chitetezo. Kusintha kwa Mlingo sikofunikira.
Atorvastatin - SZ
Wopanga kampani yaku Russia Star Star.
Amalembera mankhwalawa osakanikirana kapena osadziwika mtundu wa hypercholesterolemia, wokhala ndi matenda a mtima, ischemic matenda amtima motsutsana ndi maziko a cholesterol yayikulu. Itha kulimbikitsidwa kwa odwala monga prophylactic kuti muchepetse chiopsezo cha matenda amtima.
Wogulitsa mankhwala Atorvastatin kampani yaku Ukraine yopanga Pharmac.
Tengani kamodzi / tsiku, mosasamala chakudya, koma nthawi yomweyo. Mlingo umakhazikitsidwa ndi adokotala potengera kupimidwa kwa magazi.
Itha kuperekedwa kwa ana, achinyamata ochepera zaka 18, omwe ali ndi vuto la chibadwa, okhala ndi ziwopsezo zambiri pakulimbikitsa matenda a mtima.
Wopanga Kiev Vitamini Chomera.
Amawonetsedwa kuti agwiritsidwe ntchito ndi cholesterol yambiri, triglycerides, odwala matenda a shuga kuti achepetse vuto la kugunda kwa mtima, sitiroko.
Sitikulimbikitsidwa kuphatikiza ndi fibrate, cyclosporine, erythromycin - chiopsezo chokhala ndi myopathy chikuwonjezeka. Osamamwa nthawi yomweyo ndi maantacid, colestipol, popeza m'mimba mankhwalawa amalephera, kugwira ntchito kwake kumachepa.
Gome lofanizira
Gome likuwonetsa mtengo wapakati wa mankhwala ku Russia.
Dzina lamankhwala | Mlingo / kuchuluka kwa mapiritsi pa paketi iliyonse | Mtengo wapakati, pakani. |
---|---|---|
Liprimar | 10, 20 mg: 14, 28, 30, 35, 50, 56, 100 ma PC. | 610-2900 |
Atoris | 5, 10, 20, 40 mg: 30, 60, 90 ma PC. | 198-1535 |
Liptonorm | 10, 20 mg: 7, 10, 14, 20, 28, 30, 32 ma PC. | 200-700 rub. |
Thorvacard | 10, 20, 40 mg: 30 kapena 90 ma PC. | 301-1800 |
Tulip | 10, 20, 40 mg: 30 kapena 90 ma PC. | 226-1200 |
Atorvastatin-Teva | 10, 20, 40, 80 mg: 30, 60, 90 ma PC. | 205-810 |
Atorvastatin-Obl | 10, 20, 40, 80 mg: 10, 14, 15, 20, 30 ma PC. | 200-400 |
Novostat | 10 mg: 10, 20, 30, 60, 100 ma PC. | 95-500 |
Atomax | 10, 20 mg: 30, 40, 50 ma PC. | 225-610 |
Anvistat | 10, 20 mg: 14 kapena 30 ma PC. | 200-300 |
Atorvastatin-SZ | 5, 10, 20, 40 mg: 10, 14, 30 ma PC. | 154-500 |
Atorvacor | 10, 20 mg: 30, 60 ma PC. | 379-700 |
Livostor | 10, 20, 40 mg: 30 ma PC. | 385-700 |
Hypolipidemic mankhwala a gulu la statin ndi mankhwala omwe mumalandira. Zitha kugulidwa pamisika yogulitsa kapena pa intaneti.
Kodi pali kusiyana kotani pakati pa mankhwala ndi atorvastatin ndi simvastatin
Mankhwalawa onse amagwiritsidwa ntchito kuti muchepetse cholesterol yayikulu, triglycerides. Koma Atorvastatin ndi mankhwala a m'badwo wachitatu, imagwira ntchito kawiri konse monga Simvastatin ndi misonkho. Zimayambitsa zovuta zingapo, ndizogwirizana ndi mankhwala ena.
Ngakhale mankhwalawa amasiyanasiyana mu mphamvu ya achire, kusankha komaliza kumadalira mtundu wa hypercholesterolemia, matenda omwe alipo.
Atorvastatin amadziwika kuti ndi amodzi mwa mankhwala othandiza kuchepetsa matenda a lipid. Kulekerera bwino, kumapereka zotsatira zosatha. Mankhwala ena adzakhazikitsidwa ndi dokotala yemwe adzayesere kuopsa komanso kuvulaza.
Ndimalo ati a atorvastatin omwe ndiyenera kusankha?
Zothandiza kwambiri, zotetezeka, zongoyerekeza zimaganiziridwa ngati mankhwala oyamba - Liprimar. Ngati bajeti imalola, ndikofunikira kugula mankhwalawa. Anzanu odalirika - Tulip, Torvakard, Atoris. Mankhwala ena amakhala ndi mbiri yabwino. Muyenera kusamala makamaka ndi malo otsika mtengo. Ma atorvastatins amenewa amapangidwa kuchokera ku zinthu zotsika mtengo, mwina posokoneza.
Kodi ndiyenera kumwa atorvastatin?
Ma statin onse amatengedwa moyo kapena maphunziro atali kwambiri. Atorvastatin amachotsedwa m'thupi pakatha maola 20-30. Pambuyo pochotsa, maumboni am'mbuyomu a cholesterol synthesis amayambiranso. Mlingo wake wamagazi umayamba kuchuluka pang'onopang'ono, kubwerera manambala oyamba. Pazifukwa zomwezo, mankhwalawa amayenera kumwedwa popanda kuchotsera, chilichonse chomwe chimachepetsa mphamvu ya mankhwalawa.
Mutha kukambirana ndi dokotala wanu kuthekera kwa tchuthi chamankhwala ngati, pazifukwa zina, kusokonezeka ndikofunika kwa inu.
Ndi zakudya ziti zomwe ziyenera kutsatiridwa panthawi ya atorvastatin?
Chithandizo cha atorvastatin chimaphatikizapo zakudya zomwe zimathandizira cholesterol yotsika. Maziko azakudya ayenera kukhala tirigu, zipatso, masamba. Pulogalamu yomwe mungakonde ndi mapuloteni ndi mtedza, nthangala, nyemba, nsomba, mkaka wopanda mafuta. Ndikofunikira kuchepetsa kuchuluka kwa nyama yofiira, mafuta a nyama, mchere. Mowa umatha kumledzera, koma pang'ono.
Madokotala amati za atorvastatin
Atorvastatin ndiye statin wodziwika kwambiri padziko lapansi. Ndiwotsika mtengo, koma nthawi yomweyo imalola kukwaniritsa cholesterol yochepa mwa odwala ambiri. Madokotala amalankhula zabwino za atorvastatin, ndikuwonetsa Liprimar ndi Tulip pakati pazina zonse. Kuchokera pamalingaliro awo, atorvastatin ndi mankhwala odalirika, oyesedwa pazomwe adakumana nazo, mphamvu yake yomwe imatsimikiziridwa ndi chiwerengero chachikulu cha maphunziro. Inde, ndi mankhwala ochepa omwe adaphunziridwa bwino kwambiri. Ziyeso zoposa 400 zamankhwala, momwe odwala oposa 80,000 adatenga nawo mbali, adadzipereka ku Liprimaru kokha.
Madokotala ambiri amawona kuchuluka, komanso kuchuluka kwa zotsatira zoyipa, zomwe zimasiyanitsa atorvastatin ndi simvastatin kapena lovastatin. Kuphatikiza apo, ndi zotsika mtengo kuposa rosuvastatin, zomwe zimapangitsa kuti mankhwalawo athe kufikira anthu onse. Izi ndizofunikira kwambiri chifukwa muyenera kuzitenga kuti mukhale ndi moyo.
Zinthu zomwe zidakonzedwa ndi olemba polojekitiyi
malingana ndi ndondomeko yakusinthaku.