Mitundu ya kusanthula kwamachitidwe amwazi m'magazi, decoding, zifukwa zowonjezera ndikuchepetsa zizindikiro patebulopo
Kuwerengera magazi kokwanira (KLA) ndiko kuphunzira koyamba kuyamba kupezeka kwa matenda kapena kuwunika koyesedwa ndi dokotala ngati mbali imodzi ya mayeso azachipatala apachaka. Popanda kuyesa kosavuta koma kofunikira, ndizosatheka kuyesa kudziwa momwe thanzi laanthu lilili. KLA amatchedwa kuyesa kwachipatala wamba kapena kungoyesa chabe zamankhwala, koma palinso mtundu wofotokozedwa, womwe umaphatikizapo kufufuza mwatsatanetsatane njira ya leukocyte ndipo umagwiritsidwa ntchito wodwala akakhala ndi zizindikiro za matendawa.
Monga gawo la KLA, maselo onse atatu am magazi amayesedwa: Maselo ofiira amwazi omwe amachititsa kupuma ndi ziwalo, ma cell oyera am'magazi - omenyera chitetezo cha mthupi, ndi mapulateleti - oteteza ku magazi. Komabe, labotale singadziwe kuchuluka kokha kwa maselo amenewa. Mtundu uliwonse wam'magazi umakhala ndi zowonjezera zingapo zomwe adotolo amatha kuwunika mbali zosiyanasiyana za moyo wa chinthu china. Kuwona zotsatira za kuyezetsa magazi ambiri ndi ntchito ya dokotala wokhoza, wothandizira kapena dokotala wa ana, chifukwa si manambala okha omwe alembedwako, komanso kuphatikiza kupatuka kuzinthu zomwe zimachitika nthawi zonse, komanso ndi chidziwitso chomwe chapezeka pakuwunika, kufufuza ndi njira zina zofufuzira, ndizofunikira.
Magazi kuti awerenge mwatsatanetsatane mu odwala achikulire amatengedwa kuchokera kuchala chala pogwiritsa ntchito chofukizira, kapena kuchokera mu mtsempha wokhala ndi syringe. Mu makanda, KLA nthawi zina imayenera kutengedwa kuchokera kumakutu kapena chidendene, chifukwa zala ndizochepa kwambiri ndipo ndizovuta kulowa mitsempha. Amakhulupirira kuti magazi a venous ndi ofunikira kufufuza - ali ndi maselo ofiira am'magazi ndi hemoglobin kuposa magazi a capillary. Kuphatikiza apo, ndizotheka kutenga zinthu zambiri kuchokera mumtsempha nthawi imodzi, kuti ngati zowunikira zowonjezera ndizofunikira, munthuyo sayenera kutumizidwa ku labotore.
Pakadali pano, zipatala zambiri ndi zipatala zilinso ndi pulogalamu yochita kusanthula. Kwa iye, magazi omwe amachotsedwa kwa wodwalayo nthawi yomweyo amawayika mumtsuko wapadera ndi anticoagulant - wochotseredwa. Wowunikirayo amasalira kwambiri ndikufulumizitsa njira yopezera zotsatira za kuyesedwa kwa magazi, komabe, ngati zopatuka zazikulu kuchokera pazomwe zimapezeka zizidziwitso, ngakhale makina aluso kwambiri a m'badwo wachitatu amatha kupanga cholakwika pakuwerengera. Chifukwa chake, zitsanzo zilizonse zomwe zimatengedwa zimatsimikiziridwa kuti ziyenera kuyikidwa pakayilo lagalasi.
Zomwe zimapezeka zimayikidwa muyezo ndipo zimatumizidwa kwa dokotala kapena zimaperekedwa kwa wodwala. Ngati phunzirolo lidachitidwa "mwanjira yakale", sizingakhale zovuta kumvetsetsa zolemba zothandizira zasayansi, chifukwa mayina athunthu kuzidziwitso zawo komanso zikhalidwe zawo zidzawonetsedwa pamenepo. Koma ngati kuyezetsa magazi konse kwachitika pang'onopang'ono, chikalata chomaliza chikhala chosindikizira chomwe chili ndi zilembo zingapo zachilatini. Apa mudzafunika kuti muwerenge zotsatira, ndipo tikufotokozerani zonse zofunikira: kuyezetsa magazi konse kwa amayi, abambo ndi ana amisinkhu yosiyanasiyana mwanjira ya matebulo ndi mndandanda wa zifukwa zomwe zingapangitse kuti ziwonjezere kapena kuchepetsedwa.
Pamalo otseguka a netiweki mutha kupeza matebulo ofanana amitundu osiyanasiyana okhudzana ndi kufunika kwake, ndipo zambiri zomwe zimasungidwa muzo zimasiyana pang'ono. Izi sizoyenera kuda nkhawa nazo, chifukwa mtengo wazidziwikire umafotokozedwa momveka bwino kuchokera manambala wamba. Kuphatikiza apo, zotsatira za kuyezetsa magazi kothekera zimatha kuweruzidwa molumikizana ndi zotsatira za mayeso ena - ndizosatheka kukhazikitsa kuzindikira koyenera pogwiritsa ntchito KLA yokha, ndipo palibe chifukwa choyesera kutero.
Momwe mungakonzekere musanalandire magazi kuti mupeze zamankhwala osokoneza bongo?
Namwino amatulutsa magazi kuchokera kwa wodwala kwa mphindi zochepa, njirayi siyichititsa kusangalala kwapadera. Kuunika kwamomwemo, monga zina zilizonse, kumafunikira kukonzekera ndi kutsatira zingapo zosavuta:
- magazi amayenera kumwedwa pamimba yopanda kanthu,
- chakudya chamadzulo m'mawa sichikhala ndi tiyi komanso khofi wamphamvu, ndipo ndibwino kuti musamwe zakudya zamafuta ndi mowa kwa masiku atatu,
- Maola 24 ayenera kupewa njira iliyonse yamafuta (kusamba, sauna) ndi kulimbitsa thupi,
- kuyesedwa kumachitika m'mawa kwambiri, choyambirira, njira zamankhwala zisanachitike (ma dontho, jakisoni, radiology),
- Wodwalayo atabwera ku labotale, ndikofunika kuti akhalebe kwa mphindi khumi ndi zisanu musanatenge magazi, kuti apume ndikukhala chete.
- kudziwa kuchuluka kwa shuga m'magazi, wodwalayo sayenera kutsuka mano, kumwa tiyi kapena khofi m'mawa musanapendeketsedwe, ngakhale "m'mawa wanu uyambira ndi khofi", muyenera kupewa,
- komanso musanatenge magazi, sibwino kumwa mankhwala a mahomoni, maantibayotiki, ma diuretics ndi mankhwala ena,
- masabata awiri musanawunikidwe, muyenera kusiya kumwa mankhwala omwe amachepetsa kuchuluka kwa lipids m'magazi (onani ma statins kuti muchepetse cholesterol),
- ngati kuli kotheka, kuunikanso kusanthula kuyenera kutengedwa nthawi yomweyo ya labotale.
Mafuta osanthula am'magazi
Chizindikiro | Norm |
Mapuloteni onse | 63-87 g / l |
Zigawo zamapuloteni: |
- albin
- ma globulins (α1, α2, β, γ)
- 35-45 g / l
- 21.2-34.9 g / l
- akazi 44-97 ma micromoles pa lita
- amuna 62-124
- Mwa amuna - 0.12-0.43 mmol / l
- Mwa akazi - 0,24-0.54 mmol / l
- azimayi ndi okulirapo kapena lofanana ndi 1.2 mmol pa lita
- amuna 1 mmol pa lita
- Mwa amuna - mpaka 33,5 U / L
- Mwa akazi - mpaka 48.6 U / L
Mapuloteni onse ndi zigawo zake
Mapuloteni amagwira ntchito yofunika kwambiri m'thupi, amathandizira pakupanga maselo atsopano, kupangika kwa chitetezo chokwanira komanso kusamutsa zinthu. Mapuloteni nthawi zambiri amakhala ndi amino acid 20 ofunika, ngakhale atha kuphatikiza mavitamini, zinthu zopanda pake (zitsulo), ndi zomanga thupi ndi zotsalira za lipid.
Gawo lamadzi limakhala ndi mapuloteni pafupifupi 165, omwe amasiyana mu kapangidwe kake m'thupi. Mapuloteni onse amagawidwa m'magulu atatu kapena magawo awiri: albin, globulin (α1, α2, β, γ) ndi fibrinogen. Popeza mapuloteni amapangidwa makamaka m'chiwindi, zomwe zimapangidwa zimawonetsa ntchito za chiwalochi.
Kutsika kwa mapuloteni onse kumatchedwa hypoproteinemia (onani mapuloteni onse m'magazi). Izi zimachitika pomwe:
- kuchuluka kwa mapuloteni (zamasamba, zakudya zopanda protein),
- kuchuluka kwa mkodzo mumkodzo (matenda a impso, proteinuria ya amayi apakati),
- kuchepa kwa magazi (nthawi yayitali, mphuno),
- kuyaka, makamaka ndi maluwa,
- kuchuluka kwa plasma pamimba pamimba (ascites), pleural cavity (exudative pleurisy), pericardium (pericardial activation),
- neoplasms yoyipa (khansa yam'mimba, khansa ya chikhodzodzo),
- kuphwanya mapangidwe a mapuloteni (hepatitis, cirrhosis),
- chithandizo cha nthawi yayitali ndi glucocorticosteroids,
- kuchepa mayamwidwe zinthu (enteritis, colitis, celiac matenda, kapamba).
Kuwonjezeka kwa mapuloteni onse amatchedwa hyperproteinemia, izi zimatha kukhala zopanda malire komanso zopanda malire. Kukula kwamapuloteni kumachitika ndikamwalira kwa madzi am'madzi a kolera (kolera, kusanza mobwerezabwereza). Kuwonjezeka kwathunthu kwa mapuloteni kumachitika mwa njira zotupa (chifukwa cha ma globulins), myeloma. Kugwira ntchito yakuthupi ndikusintha kwa thupi kumasintha kugwiritsidwa ntchito kwa zinthu ndi 10%.
Zifukwa zazikulu zakusintha kwa kuchuluka kwa mapuloteni
Zigawo zamapuloteni ndi: albin, globulin ndi fibrinogen. Fibrinogen samapezeka pakuwunika kwa biochemical. Puloteni iyi imawonetsa ntchito ya kupangika kwa magazi. Amatsimikiza mu kusanthula koteroko monga coagulogram.
Albumin | Ma Globulins | ||||||||
Ma-globulins:
Β- ma globulins:
Γ- ma globulins:
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Zifukwa zakukula | Zifukwa zakuchepa |
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Uric acid
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Mwazi wamagazi
Glucose ndiye chizindikiro chachikulu cha kagayidwe kazachilengedwe. Ichi ndi chinthu chachikulu chopanga mphamvu kulowa mu cell, ndimachokera ku glucose ndi oxygen komwe khungu limalandira mafuta amoyo wina.
Glucose amalowa m'magazi atatha kudya, kenako amalowa m'chiwindi, pomwe amawagwiritsa ntchito ngati glycogen. Njira izi zimayendetsedwa ndi mahomoni a pancreatic - insulin ndi glucagon (onani kuchuluka kwa glucose).
- Kuperewera kwa shuga m'magazi kumatchedwa hypoglycemia.
- Kuchuluka - hyperglycemia.
Nchiyani chimayambitsa kusinthasintha kwa kuchuluka kwa shuga m'magazi?
Hypoglycemia | Hyperglycemia |
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Mavuto a Pigment Metabolism
Mu thupi la munthu mumakhala ma protein ena achikuda. Nthawi zambiri awa amakhala ma peptides omwe amakhala ndi chitsulo chilichonse (chitsulo, mkuwa). Izi ndi monga: hemoglobin, cerulloplasmin, myoglobin, cytochrome ndi ena. Zotsatira zomaliza zopezeka pamapuloteni oterewa ndi bilirubin ndi tizigawo tating'ono. Chimachitika ndi chiyani bilirubin mthupi?
Selo yofiyira ikatha ndulu yake, miyala yake imasweka. Chifukwa cha biliverdin reductase, bilirubin imapangidwa, yotchedwa mwachindunji kapena mwaulere. Kusiyanitsa kwa bilirubin kumeneku ndi poizoni thupi lonse, makamaka ubongo. Koma chifukwa chakuti limamangilira mwachangu kwa magaziin albumin, thupi silikhala ndi poizoni. Koma ndi hepatitis, cirrhosis, ndizokwanira, chifukwa sizimangiriza glucuronic acid.
Kuphatikiza apo, m'maselo a chiwindi, bilirubin yosalunjika imamangidwa ku glucuronic acid (kutembenuka kukhala owongoka kapena owongoka, osakhala poizoni), magwiridwe ake amakhala okwera kokha ndi dyskinesia wa biliary, omwe ali ndi matenda a Gilbert (onani zifukwa zoyipa za bilirubin m'magazi). Pakuwunika, bilirubin mwachindunji imakula ndikuwonongeka kwa maselo a chiwindi (mwachitsanzo, ndi hepatitis).
Kenako bilirubin imalowa mu ndulu, yomwe imatengedwa kuchokera ku ma hepatic ducts kupita kwa chikhodzodzo, kenako imayikidwa mu lumen ya duodenum. Apa urobilinogen amapangidwa kuchokera ku bilirubin, yemwe amamwa kuchokera m'matumbo ang'onoang'ono mpaka m'magazi, ndikalowa impso, amapaka mkodzo wachikasu. Zotsalira, zomwe zimafikira m'matumbo, pansi pa zochita za mabakiteriya zimakhala stercobilin ndikuwathandiza ndowe.
Chifukwa chiyani jaundice limachitika?
Pali njira zitatu:
- Kuchulukana kwa hemoglobin ndi mapuloteni ena a pigment (hemolytic anemia, snakebites, pathological spleen hyperfunction) - mwachindunji bilirubin amapangika pamlingo waukulu kwambiri kotero kuti chiwindi sichimakhala ndi nthawi yopukutira ndi kuwonetsera,
- matenda a chiwindi (hepatitis, cirrhosis, neoplasms) - pigment imapangidwa modabwitsa, koma maselo a chiwindi omwe akhudzidwa ndi matendawa sangathe kugwira ntchito yawo,
- kuphwanya kutuluka kwa ndulu (cholecystitis, cholelithiasis, pachonditis cham'mutu, zotupa za mutu wa kapamba) - chifukwa cha kupindika kwa mapindikidwe am'mimba, bile simalowa m'matumbo, koma limadziunjikira m'chiwindi, ndikupangitsa kuwonongeka kwa maselo ake ndikubwerera kwa bilirubin m'magazi.
Zinthu zonse zitatuzi ndizowopsa pa thanzi la munthu, zimafunikira kuchipatala msanga.
Lipid metabolism kapena cholesterol
Lipids amagwira ntchito yofunika kwambiri m'moyo wa selo. Amatenga nawo mbali pomanga khoma la maselo, mapangidwe a bile, mahomoni ambiri (maimuna ndi akazi ogonana, ma corticosteroids) ndi vitamini D. Fatty acid ndi gwero lamphamvu kwa ziwalo ndi minofu.
Mafuta onse mthupi la munthu amagawidwa m'magulu atatu:
- triglycerides kapena mafuta osalowerera ndale,
- cholesterol yathunthu ndi zigawo zake,
- phospholipids.
M'magazi, lipids ali mumtundu wa mankhwala awa:
- Ma chylomicr - amakhala makamaka ndi ma triglycerides,
- highensens lip liprrinsins (HDL) - monga 50% mapuloteni ¸ 30% phospholipids ndi 20% cholesterol,
- lowensens lipoproteins (LDL) - muli 20% mapuloteni, 20% phospholipids, 10% triglycerides ndi 50% cholesterol,
- otsika kwambiri lipoproteins (VLDL) - amapangika pakutha kwa LDL, kuphatikiza cholesterol yambiri.
Chofunika kwambiri pakuwunika ndi kuchuluka kwa cholesterol, LDL, HDL ndi triglycerides (onani magazi a cholesterol). Mukamamwa magazi, ziyenera kukumbukiridwa kuti kuphwanya malamulo okonzekera komanso kugwiritsa ntchito mafuta omwe amapezeka m'mafuta kumatha kuyambitsa zolakwika zazikulu pazotsatira za kusanthula.
C cholesterol chonse
- myxedema,
- matenda ashuga
- mimba
- Hyperlipidemia yapabanja,
- cholelithiasis
- chilonda chachikulu komanso chamba
- zamankhwala zapachifuwa ndi zamkati,
- glomerulonephritis,
- uchidakwa
- matenda oopsa
- myocardial infaration
- matenda a mtima
- zotupa zoyipa za chiwindi,
- matenda a chiwindi,
- nyamakazi
- Matenda a chithokomiro komanso matenda a parathyroid,
- kusala
- malabsorption wa zinthu
- Matenda oletsa kupuma a m'mapapo
Triglycerides
- matenda a chiwindi,
- uchidakwa
- mankhwala ozunguza bongo a chiwindi,
- kuperewera kwa biliary (biliary) chiwindi,
- cholelithiasis
- chilonda chachikulu komanso chamba
- aakulu aimpso kulephera
- matenda oopsa
- myocardial infaration
- matenda a mtima
- mimba
- matenda am'mimba,
- hypothyroidism
- matenda ashuga
- gout
- Down syndrome
- pachimake porphyria
- matenda osapatsirana a m'mapapo,
- Matenda a chithokomiro komanso matenda a parathyroid,
- kuperewera kwa zakudya m'thupi
- malabsorption
Kuchulukitsa kwa cholesterol yamagazi:
- 5.2-6.5 mmol / L - kuchuluka pang'ono kwa zinthu, chiwopsezo cha atherosulinosis,
- 6.5-8.0 mmol / L - Kuchulukitsa koyenera, komwe kumasinthidwa ndi zakudya,
- opitilira 8.0 mmol / l - mulingo wambiri wa chinthu chomwe chimafunikira kulowererapo kwa mankhwala.
Ma syndromes asanu azachipatala, omwe amatchedwa dyslipoproteinemias, amasiyanitsidwa potengera kusintha kwa lipid metabolism index (1,2,3,4,5). Izi pathological zinthu ndi harbinger matenda oopsa, monga ubongo arteriosclerosis, matenda a shuga ndi ena.
Alanine aminotransferase ndi aspartate aminotransferase
Ma enzyme amenewa amapereka kusintha kwa ma amino acid m'magazi amisilini: aspartate ndi alanine. AST ndi ALT zimapezeka zochuluka mu minyewa ya chiwindi, minofu yamtima, komanso minofu ya mafupa. Kuchulukitsa ndimwazi kumawonetsera kuwonongeka kwa maselo a ziwalozi, ndipo kukwera kwakukulu kwa michere, maselo ochulukirapo amafa.
Malangizo a Kupititsa patsogolo Enzyme: | Ndi matenda ati omwe amawonjezera AST ndi ALT? |
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Alkaline phosphatase
Enzyme iyi imayambitsa kuchotsedwa kwa phosphoric acid ku mankhwala ophatikizira ndi kutulutsa phosphorous mkati mwa khungu. Alkaline phosphatase ili ndi mitundu iwiri: hepatic ndi fupa. Zomwe zimapangitsa kuti enzyme iwonjezeke:
- nyamakazi sarcoma,
- mafupa metastasis
- myeloma
- lymphogranulomatosis,
- chiwindi
- kuwonongeka kwa poizoni ndi mankhwala osokoneza bongo ku chiwindi (aspirin, cytostatics, njira zakulera zamkamwa, tetracycline),
- mukamachiritsa,
- matenda a cytomegalovirus,
- mafupa ndi mafupa (kuwonongedwa kwa mafupa).
Γ-glutamyl kutulutsa
GGT imakhudzidwa ndi kagayidwe ka mafuta, kutumiza cholesterol ndi triglycerides mkati mwa cell. Kuchuluka kwa enzyme komwe kumapezeka mu chiwindi, prostate, impso, kapamba. Zochita zake m'mwazi zimawonjezereka ndi:
- Matenda a chiwindi omwe atchulidwa pamwambapa,
- kuledzera
- matenda ashuga
- matenda mononucleosis,
- kulephera kwa mtima.
Chopanga kinase
CC amatenga nawo gawo la kusintha kwa kusintha kwa metaboline ndi kukonza kagayidwe kazachilengedwe mu khungu. Ili ndi 3 subtypes:
- MM (enzyme yomwe ili m'matumbo a minofu)
- MV (ili mu minofu ya mtima)
- BB (mu ubongo).
Kuwonjezeka kwa magazi a chinthu ichi nthawi zambiri kumachitika chifukwa cha kuwonongeka kwa maselo a ziwalo zapamwambazi. Ndi matenda ati omwe amawonjezera QC?
Kuchulukitsa kwa alpha amylase | Kuchepetsa kwa alpha |
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Ma elekitironi pamagazi
Potaziyamu ndi sodium ndi ma electrolyte ofunika kwambiri m'magazi. Zitha kuwoneka kuti ndi zinthu zopanda mwayi chabe, ndipo zomwe zili m'thupi ndi zochepa. M'malo mwake, ndizovuta kulingalira chimodzi kapena chinthu chimodzi chomwe chikanachita popanda iwo.
Zomwe zimatsata zimagwira gawo lalikulu mu njira za enzyme komanso kagayidwe. Ntchito yake yayikulu ndikuyendetsa zikutulutsa zamagetsi mumtima. Kusinthasintha kwa magawo a potaziyamu kumakhala ndi vuto loipa kwambiri pa myocardium.
Momwe potaziyamu amakwezedwa amatchedwa hyperkalemia, ndipo ikachepetsedwa - hypokalemia. Kodi nchiyani chikuwopseza kuchuluka kwa potaziyamu?
- kuphwanya zamkati
- arrhythmias (atria fibrillation, intracardiac block)
- zimachitika kuchepetsa
- dontho mu kuthamanga kwa magazi
- chisokonezo.
Zowopsa zoterezi zimatha kuchitika ndi kuwonjezeka kwa kufufuza zinthu zoposa 7.15 mmol / L.
Kugwera kwam potaziyamu pansi pa 3.05 mmol / L ndiwopsezanso thupi. Zizindikiro zazikuluzikulu za kuchepa kwa chinthu zimaphatikizapo:
- nseru
- kusanza
- kufooka kwa minofu
- kuvutika kupuma
- kutulutsa kwayokha kwamadzi ndi ndowe,
- kufooka kwa mtima.
Sodium sikuchita nawo mwachindunji. Yodzaza ndi madzi akunja kwama madzi. Ntchito yake yayikulu ndikusunga osmotic kuthamanga ndi pH. Kukula kwa sodium kumachitika mumkodzo ndipo kumayendetsedwa ndi mahomoni a adrenal cortex - aldosterone.
Kuchulukitsa kwa chinthu chotsata kumatchedwa hypernatremia, ndipo kuchepa kumatchedwa hyponatremia.
Kodi kusokonezeka kwa sodium metabolic kumawonekera bwanji?
Hyponatremia | Hypernatremia |
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Pomaliza, ndikufuna kupatsa owerenga nkhaniyi upangiri: labotale iliyonse, kaya payokha kapena pagulu, ili ndi ake omwe ali ndi ma reagents, zida zake zama kompyuta. Chifukwa chake, zikhalidwe za zizindikiro zimatha kusiyanasiyana. Wothandizira Laborator akakupatsani zotsatira za kusanthula, onetsetsani kuti mfundozo zalembedwa pafomu. Pokhapokha mwa njirayi mudzatha kudziwa ngati pali kusintha pakusanthula kwanu kapena ayi.
Kodi tingaphunzire chiyani pa kuyesa kwa shuga wamagazi?
Shuga wamagazi amatchedwa glucose, yemwe amayenda m'mitsempha yamagazi, kulowa ziwalo zonse zam'magazi. Zimaperekedwa ku ziwiya zam'matumbo (kuchokera ku chakudya) ndi chiwindi (zopangidwa kuchokera ku amino acid, glycerol ndi lactate), ndipo zimatha kupezanso ndikugawa m'masitolo a glycogen m'misempha ndi chiwindi.
Thupi silingagwire ntchito popanda glucose, chifukwa mphamvu zimachokera kwa iwo, maselo ofiira am'magazi, minofu yamatumbo imaperekedwa ndi glucose. Insulin imathandiza kugaya shuga. Kutulutsa kwake kwakukulu kumachitika pakudya. Hormoni iyi imayendetsa glucose m'maselo kuti agwiritsidwe ntchito mu ATP synthesis reaction ndipo gawo limayikidwa mu chiwindi monga glycogen.
Chifukwa chake, kuchuluka kwa shuga (glucose) kwamtunduwu kumabweranso pazomwe adachita m'mbuyomu. Nthawi zambiri, ntchito ya kapamba, adrenal glands, hypothalamic-pituitary system imakhala ndi cholinga chowonetsetsa kuti glycemia ili m'malo ochepa. Pa mfundo kuyambira 3.3 mpaka 5.5 mmol / L, shuga amapezeka ndimaselo, koma samatulutsidwa mkodzo.
Kupatuka kulikonse kuzololedwa ndi thupi ndizovuta kuvomereza. Kuchuluka kwa shuga m'magazi kumatha kukhala m'mikhalidwe yotere:
- Matenda a shuga.
- Ma antibodies a insulin mu autoimmune zimachitika.
- Matenda a endocrine dongosolo: gren adrenal, chithokomiro England, ziwalo zawo - - hypothalamus ndi pituitary gland.
- Pancreatitis, chotupa cha kapamba.
- Matenda a chiwindi kapena matenda a impso.
Kuyesedwa kwa magazi kwa shuga kungawonetse zotsatira kuposa momwe zimakhalira ndi kupsinjika, kupsinjika, kuchita masewera olimbitsa thupi, kusuta, kumwa mankhwala a mahomoni, tiyi, khansa, mankhwala opatsirana.
Ndi kuwonjezeka kwakukulu kwa misempha ya shuga, ludzu limawoneka, kulakalaka kudya, kuwonongeka konsekonse, kukodza kumakhala kofulumira. Hyperglycemia yamphamvu imayambitsa kukomoka, komwe kumayambitsidwa ndi nseru, kusanza, maonekedwe a acetone mu mpweya wotuluka.
Kuchuluka kwa shuga m'magazi ozungulira kumayambitsa kuchepa kwa magazi, chitetezo cha mthupi, kukula kwa matenda komanso kuwonongeka kwa minyewa yamitsempha.
Zosakhala zowopsa bongo ndi kuukira kwa mpweya wochepa m'magazi. Izi zimachitika pamene insulin yambiri imapangidwa (makamaka ndi zotupa), matenda a impso kapena chiwindi, kuchepa kwa adrenal ntchito, hypothyroidism. Choyambitsa matenda ambiri amakhala ndi insulin.
Zizindikiro zakugwa kwa shuga zikuwoneka mwa kutuluka thukuta, kufooka, kunjenjemera m'thupi, kuchuluka kwa mkwiyo, kenako kusokonezeka kwa chikumbumtima kumachitika, ndipo ngati chithandizo sichingaperekedwe, wodwalayo amagwa.
Udindo wamagazi mthupi la munthu
Ntchito zazikuluzikulu zamagazi:
- Amapereka maselo okhala ndi zowonjezera zomwe zalandiridwa kuchokera ku mapapu ndi dongosolo logaya chakudya kuchokera kunja.
-Zichotsa mbali zomwe zimachitika munthawi ya moyo.
- Kothamangalam. Amasinthasintha kutentha kwa magawo osiyanasiyana a thupi.
- Zoseketsa. Zimasamula mahomoni opangidwa ndi maselo apadera kuchokera kumalo omwe amapanga kupita kumalo omwe amamwa.
- Yakhomo. Imathandizira kukhala ndi mchere wamchere, acid-base.
- Immunological yotchulidwa:
-Hemostasis - kukhalabe madzi amwaziwo womwewo, mapangidwe (kuwundana kwamagazi) ndi kusungunuka kwina kwake (fibrinolysis).
-Mbale amtundu wa magazi.
- mawonekedwe amtundu wa magazi pamagazi.
Kodi tingadziwe chiyani pakupenda magazi?
Yankho lalikulu mwachidule: kuphwanya njira zofunika kwambiri za thupi. Dotolo atanena kuti "kuyezetsa magazi", "kusintha" "mwa anthu wamba", "tebulo", wodwalayo akumvetsetsa kuti njira yoyamba yochira yatengedwa - akatswiri amatanthauzira. Pambuyo pokhazikitsa chomwe chimayambitsa, njira yothandizira imayikidwa.
Kuwona kwa mapangidwe a pathological amafotokozedwa ndikusintha kwadzidzidzi mu kuchuluka kwa tinthu tina timene timatengedwa mumtsinje wamagazi.
Zitsanzo:
- Aspartate aminotransferase. Enzyme imapangidwa mkati mwa maselo. Zochita zikuwonetsedwa mu minofu ya mtima, chiwindi, minofu yamatumbo, minofu yamitsempha, impso (kutsika). Zotsatira: njira za necrotic mu tinthu ta myocardium ndi chiwindi zimayambitsa kutulutsidwa kwa mapuloteni ndikulowa kwake m'magazi am'magazi, omwe amawonetsedwa mu kusanthula ngati chowonjezera cha chizindikiritso cha zinthu zomwe zidatchulidwa.
- Bilirubin. Amapangika pakasweka maselo ofiira am'magazi (maselo ofiira am'magazi), amalowa m'chiwindi, ndikuthira. Ngati pali zovuta zina pakusokonekera kwa maselo ofiira am'magazi, kapena mawonekedwe a chimbudzi chake atalephera (chikhodzodzo ndi chindulu.
Wochiritsirayo amapanga chithunzi chamankhwala pozindikira ma enzyme, mapuloteni ndi zinthu zina, pang'onopang'ono kubwereza mzere wazomwe zingayambitse matenda.
Kuchiritsa kwa kuyezetsa magazi mwatsatanetsatane
Dotoloyo akuwonetsa kutumiza izi kuti apeze zambiri kuposa KLA. Zowonjezera zimakuthandizani kuti mumvetse bwino za matendawo. Mndandanda wazinthu zosakhazikika umaphatikizapo zinthu 30. Zomwe zalandilidwa zikuwonetsa mawonekedwe a magazi, mawonekedwe owonjezeka amtundu wathunthu wa leukocyte.
Zizindikiro zachilendo za kusanthula kwamankhwala ndi zomwe zimayambitsa kupatuka
Magawo akuluakulu omwe adawerengedwa pochita kuyezetsa magazi, ndimomwe amapatsidwa, amaperekedwa pagome (kutsatsa kwina):
Nthawi zambiri mu akulu | Mu ana | ||||
Magawo omwe anafufuzidwa | Amuna | Akazi | Kuyambira pa 1 mpaka 6 zaka | Zaka 6 mpaka 12 zakubadwa | Zaka 13 mpaka 16 |
Hemoglobin (g / l) | 125-165 | 120-140 | 112-135 | 112-140 | 112-145 |
Chikalakatha (ppm) | 4,1-5,2 | 3,7-4,9 | 3,5-4,5 | 3,8-4,9 | 3,7-5,1 |
Hematocrit (%) | 39-49 | 35-45 | 35 | 37 | 39 |
Maselo oyera (Chigawo / L) | 4.1-9x109 | 3.9-10.2x109 | 5-14.5x109 | 4,5-12x109 | 4.3-9.8x109 |
ESR (mm / h) | 1-12 | 2-15 | 4-12 | 4-12 | 4-15 |
Chizindikiro cha utoto | 0,85-1,15 |
Mavuto omwe akuwoneka popitilira zomwe zalembedwazo:
- Pamwambapo:
- Hemoglobin - mavuto mu mtima, kupuma kulephera.
Kuunikira kuwerengera kwa hemoglobin, puloteni yofunika kwambiri m'thupi lathu, ndizotheka kuyezetsa magazi
- Pansipa
- Hemoglobin - autoimmune pathologies, magazi mkati, kuchepa kwa magazi m'thupi ndiubongo.
- Maselo oyera - kuperewera kwa zakudya, njira za oncological, kuledzera.
- ESR - myodystrophy yomwe ikupita patsogolo, njala, kusowa kwamchere wamchere.
- Maselo ofiira - magazi m'thupi.
- Hematocrit - magazi m'thupi.
- Chizindikiro cha utoto ndi kuchepa kwamagazi.
Decoding of biochemical magazi mayeso
Tsimikizirani matenda osiyanasiyana mothandizidwa ndi kuyesedwa kwa magazi kwakanema (cholembedwa). Akuluakulu, wamba patebulo kumatengera zaka, nthawi yachilengedwe, kudya, komanso zakudya. Izi zimagwiranso ntchito kwa ana. Chifukwa chake, wodwalayo ayenera kutsatira zokhazikitsidwa zofunika pokonzekera kuwunika.
Kafukufuku waku Laborat:
- Kutaya kwa zakudya zazing'ono komanso zazikulu.
- Magawo a matenda obwera a ziwalo zamkati.
- Kusintha kwachilengedwe.
- Kupezeka kwa neoplasms.
Zizindikiro zachilendo zamankhwala am'magazi komanso zomwe zimayambira
Gome limakhala ndi zofunikira za zigawo zazikulu zophunziridwa mwa akulu ndi ana panthawi yopereka magazi kuti aunike zamankhwala.
Ndikumasulira kwamtsogolo:
Dzinalo | Akuluakulu | Ana |
Mapuloteni onse (g / l) | 63-85 | 58-78 |
Hemoglobin (g / l) | 125-165 | 112-145 |
Albumin (g / l) | 35-49 | 38-53 |
Bilirubin yonse (μmol / L) | 22,-17,5 | 8,5-21 |
Aspartate aminotransferase (unit / L) | Mpaka 35 | Mpaka 40 |
Alanine aminotransferase (Unit / L) | Mpaka 42 | Mpaka 39 |
C cholesterol chokwanira 1 | Kufikira pa 5 | 3,3-6,1 |
Urea 1 | 2,5-7,1 | 4,2-6,6 |
Triglycerides 1 | 0,55-1,65 | 0,41-1,85 |
Glucose 1 | 3,30-5,75 | 3,30-5,9 |
Sodium 1 | 130-150 | 133-157 |
Potaziyamu 1 | 3,45-5,35 | 3,7-5,1 |
Iron 1 | 11-30 | 9,1-31,7 |
1 unit ya miyeso - mmol / L.
Zoyipa zomwe zitha kuwonetsedwa ndizowonjezera:
- Mapuloteni onse - njira zopatsirana, khansa.
- Hemoglobin - njira ya mtima yamitsempha, kulephera m'mapapo.
- Albumini - kuchepa kwa magazi, kusowa kwa chiwindi.
- Bilirubin okwanira - kuwonongeka kwa chiwindi, biliary thirakiti.
- Aspartate aminotransferase - myocardial infarction, chiwindi cha chiwindi.
- C cholesterol chonse - cholowa, matenda a mtima, matenda a impso, matenda a Werner.
- Urea - matenda a kwamikodzo dongosolo.
- Triglycerides - mahomoni mankhwala, kudya kwambiri, kumwa kwambiri.
- Glucose - mavuto ndi kapamba, chiwindi, impso, mtima. Matenda a shuga.
- Sodium - Zakudya zopanda mchere, yade.
- Potaziyamu - vuto la m'matumbo, zovuta za impso ndi adrenal glands.
- Iron - uchidakwa, kudya kosalamulira kwa zowonjezera pazitsulo.
Ngati ntchito yoyeserera ili pansi pazovomerezeka:
- Mapuloteni onse - kapamba, chiwindi, ndi matenda a impso.
- Hemoglobin - zotupa zamkati, khansa ya magazi.
- Albumin - chibayo, matenda a impso ndi chiwindi, kufa ndi njala.
- Total bilirubin - chifuwa chachikulu, kutopa konse, kukanika kwa impso.
- Aspartate aminotransferase - pachimake kapamba, zoopsa.
- C cholesterol yathunthu - kuchepa kwa chithokomiro, zakudya zopanda thanzi.
- Urea - kusintha kwa ziwindi mu chiwindi, kukanika kwa chithokomiro.
- Triglycerides - kuphwanya kwam'mimba, chithokomiro cha chithokomiro.
- Glucose - kukanika kwa kapamba, impso, hypothalamus, kuwonongeka kwa chiwindi, kuperewera kwa zakudya m'thupi.
- Sodium - chakudya chopanda malire, matenda a chiwindi, impso, mtima.
- Potaziyamu - kutenga okodzetsa, kutsegula m'mimba.
- Iron - kuperewera kwa zakudya, kuchepa kwa magazi ambiri, kuchepa mphamvu kwa chinthu.
Zizindikiro zabwinobwino komanso zomwe zimayambitsa kupatuka
Mtengo wake umatengera zaka, komanso momwe magazi amapezeka - capillary kapena venous.
Makulidwe wamba (mmol / l):
- Kufikira 3,3. Hypoglycemia. Kutha kwa kapamba, chiwindi, impso.
- Kuchokera pa 3.4 mpaka 5.5. Kupanda kuphwanya.
- Kuyambira 5.6 mpaka 7. Pabetes. Ngati kulibe chithandizo choyenera kumabweretsa hyperglycemia.
- Kuchokera pa 7 ndi kupitirira. Matenda a shuga.
Mlingo wa glucose | Akuluakulu (mmol / L) | Ana (mmol / L) |
Zoyimira | 3,30-5,75 | 3,30-5,9 |
Kutsitsidwa: | a) Zakudya zazitali c) matenda am'mimba, d) kuchuluka kaphatikizidwe ka insulin. | |
Kuchulukitsa: | a) kusowa kwa kapamba ndi chithokomiro b) wonenepa kwambiri. |
Kuchepetsa kachilombo ka HIV komanso kuyezetsa syphilis
Dokotala amatumiza wodwalayo kuti amupime ndi kuti adziwe matenda omwe ali ndi kachilombo ka chitetezo cha mthupi, kapena ma bacteria a paleponema, ngati pali zifukwa izi:
HIV Omukayikira:
- Wofowoka ananena momwe thupi limaperekera chithandizo cha matenda ofatsa "fuluwenza, SARS."
- Misewu yayikulu.
- Kutupa.
- Kuchepetsa thupi mwachangu.
- Zizindikiro zotsutsana za ndime zam'mbuyomu ndi zodandaula za kusanza komanso kutsegula m'mimba.
Syphilis Omwe Akukayikira:
- Kuzindikira kwa chancre.
- Dazi.
- Kutupa.
Kuzindikira kumaphatikizapo kuyamwa magazi a venous.
Othandizira zasayansi amawunika zopezeka m'njira imodzi mwanjira zitatu izi:
- Enzyme immunoassay (ELISA). Zimawonetsa kukhalapo (ndi chiwerengero chawo) cha ma antibodies (IgM, IgG, IgA) ma antigen. M'mphepete mwa cholakwika ndi ochepera 2 peresenti.
- Kufalikira kwamphamvu. Ndi ELISA wapamwamba. Zotsatira zake zimapatsanso kudalirika kwakukulu (> 99.3%), popeza nthawi yoyamba, mapuloteni amtunduwu amalekanitsidwa ndi ma electrophoresis ndi kulemera kwa maselo.
- Polymerase unyolo reaction (PCR). Kutengera ndi iwo, kuchuluka kwa makopi a RNA, ndi makope a DNA, a pathogen amawerengedwa.
Pochita, ELISA imagwiritsidwa ntchito, mutalandira zotsatira zake, cheke chimachitika ndi zonse za ELISA, komanso kufooketsa chitetezo m'thupi ndi PRC. Kuwerenganso kawiri kumathetsa chiopsezo chodzimasulira molakwika pazomwe zalandira. Zotsatira zomaliza zimakonzedwa ndi adokotala okha.
Decryption ya mayeso a matenda a TORCH
Diagnosis imachitika pofuna kudziwa mu akazi omwe akukonzekera kukhala ndi pakati:
- toxoplasmosis, rubella, cytomegalovirus matenda, herpes (matenda akuluakulu).
- hepatitis B ndi C, syphilis, HIV, nkhuku, matenda a gonococcal (owonjezera).
Kunyalanyaza mayeso kumakhala ndi chiopsezo cha mavuto obwera ndi mwana wosabadwa, wolakwika, komanso kulumala kwa mwana.
Enzyme immunoassay
Njira zamakono zodziwira:
- tizilombo toyambitsa matenda
- matenda oncological
- kusokonezeka kwa mahomoni.
Ubwino wake:
- Kuzindikira vuto m'magawo oyamba.
- Kuchulukitsa kwachilendo komwe kumachepetsa mwayi wolakwitsa kutengera zizindikiro zamtanda.
Miyezo ya shuga ya magazi imaperekedwa ndi WHO
Awa ndi miyeso yovomerezeka ya shuga, ndiko kuti, zomwe zili mumwazi ziyenera kukhala m'magazi otengedwa kuchokera mu mtsempha kapena chala chakumimba chopanda kanthu.
M'badwo | Msuzi wa shuga |
Masiku 2 - mwezi umodzi | 2.8 - 4.4 mmol / L |
Mwezi 1 - zaka 14 | 3,3 - 5.5 mmol / L |
Akuluakulu | 3.5 - 5.5 mmol / L |
Ngati zizindikirozo ndizocheperapo, ndiye kuti izi zikuwonetsa kukhalapo kwa hypoglycemia, ngati zikuwonetseratu, ndiye kuti munthuyo ali ndi vuto la hyperglycemia. Kupatuka kulikonse kuchokera pachiwopsezo chake ndizowopsa kwa thupi, amalankhula za kuphwanya kosasinthika. Komanso, ndi ukalamba, chidwi ndi insulin chimachepa chifukwa cha kufa kwa zolandilira komanso kuwonjezeka kwa thupi.
Tchati chachikulu choyesa magazi
Gome la chizolowezi choyeza magazi lithandizanso kudziwa kupatuka kwina kulikonse. Komabe, kuyerekezera kokha kwa zizindikiro zingapo kungathandize kuwunikira bwino zaumoyo. Iyi ndi imodzi mwazofala kwambiri njira zoyeserera, zomwe zimathandiza dokotala kuti adziwe zomwe zimayambitsa matenda ena ndikuzindikiritsa matenda ena a magazi ndi ziwalo zina. Kwa kuyezetsa magazi konse, magazi a capillary nthawi zambiri amatengedwa kuchokera ku chala kapena magazi kuchokera mu mtsempha. Kuyeza magazi ena sikutanthauza kukonzekera kwapadera, koma tikulimbikitsidwa kuti mupereke magazi kuti mukawone m'mawa m'mimba yopanda kanthu. Otsatirawa ndi gome la zoyeserera zamagazi ambiri mwa munthu wamkulu wolemera thupi.
Zizindikiro, mayunitsi
Kulekerera kwa glucose kuyesedwa
Ngati magazi a capillary kapena venous atengedwa phunziroli, zotsatira zake zimakhala zosiyana pang'ono. Zakudya zabwinobwino zam shuga ndikatha kudya m'munthu wathanzi zimasiyana pang'ono.
Pozindikira matenda a shuga, magazi amayenera kuwayezetsa pafupipafupi kuti atsimikizire kupatuka kwatsatanetsatane kuzungulira chizolowezi. Chowongolera chothandizira chimapangidwa kuti chifanizire zotsatira ndi mawonekedwe a matendawa ndi zizindikiro zakufufuzira. Kuzindikira kwa matenda a shuga kumakhazikitsidwa ndimagulu a glucose opitilira kuyambira 9 mpaka 16 ndikusintha kwina mkati mwa malire awa.
Kufufuza zotsatira | Magazi a capillary | Magazi magazi |
Mulingo wabwinobwino | Asanadye, 3.5 - 5.5 mmol / L | 3.5 - 6.1 mmol / L |
Patatha maola awiri mutadya | mpaka 7.8 mmol / l | |
Prediabetes boma | Asanadye 5.6 - 6.1 mmol / L | 6.1 - 7 mmol / l |
Patatha maola awiri mutadya 7.8 - 11.1 mmol / L | 7.8 - 11.1 mmol / L | |
Matenda a shuga | Musanadye, kuyambira 6.1 mmol / L | kuchokera 7 mmol / l |
Patatha maola awiri mutadya kuyambira 11, 1 mmol / l | kuyambira 11, 1 mmol / l |
Chofunika kwambiri ndi kulolera kwa glucose! Miyezoyo ikapyozedwa pang'ono, zotsatira zoyesazi zimawunika ngati prediabetes, ndiye kuti, kulolerana kwa glucose. Izi zitha kukhala zochitika zathupi, koma zitha kuwonetsa kukula kwa matenda.
Amayi, molingana ndi kayendetsedwe ka thupi lawo, amayenera kuyang'anira kuchuluka kwa shuga. Ndikofunikira kudziwa kuti kugonana koyenera sikuyenera kuyesedwa kwa shuga panthawi ya msambo. Nthawi zina, zizowongolera zowongolera zimatha kukhala zosiyanasiyana. Pa nthawi yoyembekezera, 6.3 mmol / L imawerengedwa ngati chizindikiro wamba.
Zizindikiro zikapitirira 7 mmol / l, muyenera kuyang'aniridwa ndi katswiri ndikupitiliza mayeso ena owonjezeredwa ndi dokotala. Mwa akazi, kuchuluka kwa deta sikumangotanthauza kukhalapo kwa matenda. Amayi omwe ali ndi zaka 60 zakubadwa amalangizidwa kuti azichita mayeso a shuga nthawi zonse kuti aziwonetsetsa zomwe zili komanso kuti asaphonye mphindi yokhotakhota pompopompo.
Komabe, patatha zaka 60, abambo amayenera kuyang'anira shuga wawo wamagazi. Kwa abambo akuluakulu, miyezo ya mayeso a shuga wamagazi imapangidwa m'magulu osiyana.
Zizindikiro zakuchuluka kwa shuga
Kukula kwa shuga kumatsimikiziridwa ndi zizindikiro zapadera. Amatha kuwonekera mwa akulu ndi ana.
Zizindikiro zotsatirazi zimatengedwa ngati zapadera:
- kupezeka kwa kutopa kwakukulu,
- kulakalaka kulimbana ndi maziko a kunenepa,
- pakamwa kowuma, ludzu,
- kupopa kwambiri komanso pafupipafupi,
- kukokana usiku
- mawonekedwe a zilonda, zithupsa,
- kuyabwa kosalekeza m'mphepete
- kufooketsa chitetezo chokwanira,
- kusachita bwino
- kuwonongeka kwa okalamba.
Maonekedwe a zizindikilo zotere akuwonetsa kuti ndi nthawi yoyang'ana magazi kuti apeze shuga.
Mwinanso, zizindikirazo zidzakwaniritsidwa, ndipo upangiri waluso udzafunikira kuti mupereke chithandizo chomwe mukufuna.
Kuchotsera kwa kusanthula kwa magazi a gulu ndi Rh factor
Zifukwa zosankhidwa:
- Zoperekedwa mwadongosolo.
- Kuvomerezedwa pakugwira ntchito za boma kwa anthu audindo winawake (ankhondo, apolisi).
- Kukonzekera kubereka.
Akuwonetsa magazi a wodwala a gulu linalake (Zero, A, B, AB).
Imakhazikitsa Rh wa makolo amtsogolo, potero kupewa kupewa kwa mpungwepungwe wama Rh wa mayi ndi mwana wosabadwa.
Pomaliza
Kotero kuti tebulo lokhala ndi zotsatira za kuyezetsa magazi mulibe chabodza, ndipo adotolo amatha kufotokozera bwino zotsatira ndi miyambo, achikulire ndi ana awo ndikofunika kumwa mankhwala mosamala:
- Onani nthawi yomwe muyenera kupewa kudya zakudya ndi madzi.
- Osasuta.
- Pewani kuchuluka kwambiri komanso kupsinjika.
- Masiku angapo musanapite ku labotale, siyani kudya zamkaka, mowa.
Kupeza zotsatira zopitilira muyeso kumafuna kutanthauzira kwa adokotala. Kudzichiritsa nokha kumawopseza ndi zochitika zomwe sizinachitike, chifukwa kusadziwa zambiri kungayambitse kulakwitsa koyambitsa zomwe zimayambitsa matendawa.