Zosakaniza zogwiritsidwa ntchito ndi mankhwala Trigamm ndi Mavitamini Bomwe ali ndi phindu pa njira zosachiritsika zotupa m'matenda a minofu ndi mafupa.

Thiamine - amatenga nawo mbali muzochitika za carbohydrate metabolism, mu Zozungulira Krebs ndi ATP kaphatikizidwe ndi thiamine pyrophosphate (TPF).

Cyanocobalamin - imagwira ntchito kwambiri pakapangidwe kamatumbo a myelin, imalimbikitsa metabolic acid, hematopoiesis, amachepetsa ululu womwe umayamba chifukwa cha kuwonongeka kwa dongosolo la zotumphukira m'mitsempha.

Pyridoxine - amatenga nawo mbali pazochitika za kagayidwe kazakudya zomanga thupi, zakudya zamafuta ndi mafuta.

Pharmacokinetics

Thiamine - yotengeka msanga ndi jakisoni wambiri, imalowa mu kayendedwe kamatenda, imagawidwa mosagwirizana m'thupi: maselo ofiira amwazi - 75%, mkati maselo oyera - 15%, m'magazi am'magazi - 10%. Imalowa mosavuta mu chotchinga chachikulu, BBB ndi mkaka wa m'mawere. Biotransformed mu chiwindi kuti piramidi ndi thiamine carboxylic acid. Amayamwa kuchokera ku thupi ndi impso mkati mwa masiku awiri.

Cyanocobalamin - m'magazi amamangiriza ma transcobalamins, omwe amawapititsa ku minofu. Kuyankhulana ndi mapuloteni amwazi ndikokwera, pafupifupi 90%. Amayikidwanso m'chiwindi, pomwe imatulutsidwa m'matumbo ndi bile ndipo imadziwikanso m'magazi. Cmax pambuyo jakisoni amafikira pambuyo maola atatu. Mosavuta imagunda chotchinga. Amapukusidwa makamaka m'matumbo komanso mulingo wochepetsetsa kudzera mu impso.

Pyridoxine -Pamathandizo oyenda mu intramuscular, imalowa mwachangu mu kayendedwe kazinthu. Pafupifupi 80% Vitamini pyridoxine limamangidwa kumapuloteni am magazi. Imagawidwa ndendende ziwalo zonse ndi minyewa, ndikuwoloka chikhodzicho ndikudutsa mkaka wa m'mawere. Imayikidwa mu chiwindi, pomwe imasinthidwa ndi oxidation kukhala pyridoxic acid, yomwe imatuluka mkodzo.

Lidocainelimamangidwa bwino ndi mapuloteni am magazi. Cmax m'magazi ndi i / m makonzedwe amatheka pambuyo pa mphindi 10-15. Imagawika ziwalo ndi ziwalo zathupi mkati mwa mphindi 5 mpaka 10. Mosavuta imalanda BBB ndi zotchinga zina, zotulutsidwa mkaka wa m'mawere. Zimapangidwa ndi nawo microsomal michere mu chiwindi kuti metabolites yogwira - glycinexylidine ndi monoethyl glycine xylidide. Amayamwa mu ndulu ndi mkodzo.

Kuchita

Pyridoxine timapitiriza decarboxylation wa levodopa mu minofu, motero, amachepetsa mphamvu yake mankhwalawa matenda a parkinson.

Thiamine sizigwirizana ndi mayankho okhala sulfitespopeza sichidziwika bwino mwa iwo. Thiamine imagwera motsogozedwa ndi mkuwa ndipo imataya mphamvu yake pamene pH opitilira 3.

Vitamini B12 yosagwirizana ndi mchere wazitsulo zolemera komanso ascorbic acid.

Ndi kholo makonzedwe lidocaine wa pamodzi ndi epinephrine ndi norepinephrine pali chiopsezo chowonjezeka cha mavuto pamtima.

Tsiku lotha ntchito

Ndemanga za mankhwala pakati pa ambiri odwala ndiabwino.

• «... Dotolo adazindikira kuti myalgia adamuuza Trigamm. Katemera anachitika tsiku lililonse kwa sabata limodzi. Zotsatira zake zidawonekera nthawi yomweyo. Zowawa zokoka m'misempha zidasowa, ndikuyamba kuyenda momasuka. Panalibe mavuto. Ndikupangira mankhwalawa».
• «... Ndinkafuna kuchepetsa thupi ndipo ndinali pachakudya kwa nthawi yayitali, monga momwe amandiwuzira - chakudya cholakwika. Zotsatira zake zimakhala hemoglobin wochepa, kutopa ndi kupha mphamvu kosalekeza. Adotolo adandiuza Trigamma. Mankhwala anathandiza».
• «... Ndinavulala ndikuphunzitsa simulators. Mwa mankhwala omwe adasanza ndi Trigamm. Mankhwalawa adatenga nthawi yayitali, koma pamapeto pake - kuvulala kunachira».

Malinga ndi madotolo, Trigamm ndi mankhwala othandizadi pa zovuta zomwe adanenanso asthenia, Zizindikiro zochotsa, ma psychoseskuledzera kukhumudwa, kuvulala kwamisempha. Pochita izi, ndikofunikira kuganizira za momwe thupi lawo siligwirizana mavitamini B1-B6-B12 ndi lidocaine wa. Zotsatira zake zoyipa ndi zovuta zake ndizosowa kwambiri.

Mtengo wa Trigamma, komwe ungagule

Mtengo wa ma Trigamm ampoules a 2 ml No. 10 amasiyanasiyana mkati mwa 356-420 rubles phukusi lililonse. Mutha kugula Trigamma m'mafakitala ambiri ku Moscow.

Maphunziro: Anamaliza maphunziro ku Sverdlovsk Medical School (1968 - 1971) ndi digiri ku Paramedic. Anamaliza maphunziro ake ku Donetsk Medical Institute (1975 - 1981) ndi digiri ku Epidemiologist, Hygienist. Anamaliza maphunziro omaliza maphunziro ku Central Research Institute of Epidemiology ku Moscow (1986 - 1989). Digiri Yapamwamba - Wophunzira wa Medical Science (digiri yoperekedwa mu 1989, chitetezo - Central Research Institute of Epidemiology, Moscow). Maphunziro ambiri apamwamba a matenda a mliri ndi matenda opatsirana atha.

Zokumana nazo: Gwirani ntchito ngati mutu wa dipatimenti yochotsa matenda osokoneza bongo ndi 1983 - 1992 Gwirani ntchito ngati mutu wa dipatimenti yamatenda oopsa 1992 - 2010 Kuphunzitsa ku Medical Institute 2010 - 2013

Njira yogwiritsira ntchito

Ndi ululu waukulu, mankhwalawa amayenera kuyamba ndi mu mnofu (wozama) wa 2 ml ya mankhwalawa Trigamma tsiku lililonse kwa masiku 5 mpaka 10, ndikusintha mtsogolo kuti mutenge mitundu ya pakamwa kapena jakisoni wocheperako (kawiri pa sabata kwa masabata awiri).

Zotsatira zoyipa

Thupi lawo siligwirizana. Nthawi zina, thukuta limakula, tachycardia, ziphuphu zimapezeka. Khungu limakhudzana ndi kuyabwa, urticaria amafotokozedwa.
Nthawi zina, pamakhala zochitika za hypersensitivity ku mankhwalawa, mwachitsanzo, kupupuma, kufupika, angioedema, anaphylactic mantha.

Kupanga ndi mawonekedwe a kumasulidwa

m'magalasi amdima amdima, 2 ml iliyonse, muthumba lodzaza ndi ma ampoules 5, omalizira ndi zotumphukira, mumapaketi a katoni 1 kapena 2.

Trigamm mankhwala: malangizo ntchito

Trigamma ndi mankhwala ophatikiza omwe amaphatikiza mavitamini B. Mankhwalawa samangowonjezera kagayidwe, komanso amathandizanso kupweteka komanso amathandizira kuthetsa kutupa. Mankhwalawa amalimbikitsidwa kuti amwe pokhapokha ngati akuwongoleredwa ndi dokotala, kutsatira mosamalitsa malangizo ogwiritsa ntchito.

Dzinalo Lopanda Padziko Lonse

Mankhwala a INN - Thiamine + Pyridoxine + Cyanocobalamin.

Trigamma ndi mankhwala osakaniza omwe amaphatikiza mavitamini a B.

Pazigawo zapadziko lonse lapansi za ATX, mankhwalawa ali ndi N07XX

Kutulutsa mafomu ndi kapangidwe kake

Mankhwalawa amapezeka mwanjira yothetsera vuto la mtundu wofiira, womwe umapangidwira jakisoni, mu 2 ml ampoules, omwe amaikidwa m'matakadi a 5 kapena 10 ma PC.

Kapangidwe ka mankhwalawa kumaphatikizapo pyridoxine hydrochloride, lidocaine, thiamine, cyanocobalamin. Zowonjezera: Trilon B, madzi apadera a jekeseni, kundthonium chloride ndi sodium hydroxide.

Zotsatira za pharmacological

Zotsatira za Trigamma zimachitika chifukwa cha zomwe zimagwira ntchito zomwe zimaphatikizidwa ndi mankhwalawa. Vitamini wa Gulu B amathandizira kupondereza njira zotupa ndipo amathandizanso pakufooka kwa masisitimu amanjenje ndi minyewa ya mafupa.

Thiamine yomwe ili mu Trigamma imathandizira kuti matenda a metabolism azikhala mu minyewa yamanjenje, komanso, chinthu ichi chimakhudzidwa ndi kuzungulira kwa Krebs ndikupanga ATP ndi TPF. Kutenga kwa pyridoxine mu kagayidwe ka mapuloteni, mafuta ndi chakudya kumakhala ndi zotsatira zabwino pa ntchito ya mtima, minofu ndi mitsempha.

Kutenga kwa pyridoxine mu metabolism kumathandizira pa ntchito ya mtima.

Mphatso ya lidocaine wa ku Trigamma imakhudzanso mankhwala okoma. Cyanocobalamin imathandizira hematopoiesis ndi kuchiritsa kwa myelin. Chidachi chimachepetsa kuwawa kwa kupweteka chifukwa cha kuwonongeka kwa mitsempha ya mitsempha. Kuphatikiza apo, mankhwalawa amakulitsa kuwonjezeka kwa ntchito ya folic acid.

Mafunso, mayankho, ndemanga pa mankhwala a Trigamm

Zomwe zimaperekedwa zimakonzekera akatswiri azamankhwala komanso zamankhwala. Chidziwitso chokwanira chokhudza mankhwalawa chili m'malangizo omwe amaphatikizidwa ndi zomwe amapanga ndi wopanga. Palibe chidziwitso chomwe chatumizidwa patsamba lino kapena tsamba lililonse la tsamba lathu chomwe chingagwire ntchito ngati cholowa m'malo mwapadera kwa katswiri.

Kutulutsa Fomu

Trigamma - yankho la mu mnofu makonzedwe.
2 ml mu magalasi ambiri a galasi la bulauni kapena ma ampoules a galasi yoteteza.
Ma ampoules asanu amayikidwa mu chovala cholumikizira kuchokera mu filimu ya polyvinyl chloride.
1 kapena 2 yamalumikizidwe yolumikizira yocheperako yodalira kapena yocheperako yochulukirapo komanso malangizo ogwiritsira ntchito amayikidwa pakatoni.

Zizindikiro zogwiritsidwa ntchito

Zosakaniza zogwira ntchito za Trigamma ndizothandiza mu myalgia ndi neuralgia. Mankhwalawa nthawi zambiri amawapangira paresis ya nkhope yamitsempha. Kuphatikiza apo, mankhwalawa amatha kugwiritsidwa ntchito pa matenda ashuga a chiwindi, mawonetseredwe amowa a polyneuropathy.

Kugwiritsa ntchito kwa Trigamma ndi koyenera kwa ma radicular syndromes omwe amachitika motsutsana ndi kuwonongeka kwa mawonekedwe a msana. Mwa zina, kugwiritsidwa ntchito kwa Trigamma pochiza ululu komanso kuwonongeka kwa mitsempha yotsutsana ndi maziko a shingles kungalimbikitsidwe. Mankhwala ocheperako amagwiritsidwa ntchito mu gynecology.

Mankhwala amapatsidwa neuralgia.
Mankhwala amapatsidwa myalgia.
Mankhwala amapatsidwa matenda a shuga.
Mankhwala amapatsidwa mankhwala a paresis a nkhope.

Kodi mutenge bwanji Trigamm?

Mlingo wa mankhwala amasankhidwa payekha. Nthawi zambiri, 2 ml jakisoni wa tsiku ndi tsiku wa mankhwalawa amapatsidwa masiku osachepera 7-10. Pambuyo pa izi, wodwalayo amapatsidwa mankhwala osokoneza bongo monga mapiritsi kapena jakisoni amachitika katatu pa sabata. Njira yochizira pamilandu iyi ndi pafupifupi milungu itatu.

Zokhudza mphamvu pakuwongolera njira

Mukamachita chithandizo ndi Trigamma, muyenera kusamala kwambiri mukamayendetsa.

Mu shuga mellitus, mankhwala mankhwala 2 ml 2 kawiri pa tsiku. Ikani mankhwalawa kwa milungu itatu.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Amayi sayenera kugwiritsa ntchito Trigamma podikirira kuti mwana abadwe komanso poyamwitsa.

Odwala omwe ali ndi matenda osatha a endocrine system, ndikofunikira kugwiritsa ntchito mankhwalawa mosamala kwambiri.

Mankhwala ochulukirapo a Trigrams

Ndi kuyambitsidwa mwachangu kwa Trigamm ndi kupitilira muyeso wolimbikitsidwa, zotsatira zoyipa pamtima, zomwe zimafotokozedwa ndi tachycardia, zimawonedwa. Nthawi zina, pali zizindikiro za arrhasmia. Chizungulire komanso kupweteka kumatheka. Ngati zizindikiro za mankhwala osokoneza bongo zimawonekera, chithandizo chamankhwala chikufunika.

Kuphatikiza komwe kumafunikira kusamala

Chenjezo liyenera kugwiritsidwa ntchito mwa anthu omwe ali ndi matenda a Parkinson, chifukwa pyridoxine wopezeka mu Trigamm amachepetsa mphamvu ya Levodopa.

Vitamini B12 yomwe ilipo mu Trigamma sangaphatikizidwe ndi mchere wazitsulo zazikulu ndi ascorbic acid.

Kodi ndingagule popanda kulandira mankhwala?

Mankhwala sayenera kugula mankhwalawo.

Analogue ya mankhwala Combilipen.
Analogue ya mankhwala Glycine.
Analogue ya mankhwalawa ndi Hypoxene.Analogue ya mankhwala Milgamm.
Analogue ya mankhwala Vitagamm.
Analogue ya mankhwalawa ndi Vitaxone.

Ndemanga za Trigamm

Mankhwalawa agwiritsidwa ntchito kwazaka zambiri. Malingaliro a akatswiri, madokotala ndi odwala za Trigamm nthawi zambiri ndiabwino.

Svetlana, wazaka 35, Vladivostok.

Kugwira ntchito ngati neurologist, nthawi zambiri ndimalemba kugwiritsa ntchito Trigam kwa odwala omwe ali ndi myalgia, komanso chithandizo chovuta cha matenda amitsempha omwe amachitika motsutsana ndi maziko a osteochondrosis. Mankhwalawa amaloledwa ndi odwala. Sindinakumanepo ndi mawonekedwe a zovuta zina mwa odwala.

Grigory, wazaka 45, Moscow.

Kugwiritsa ntchito kwa Trigamm kwandithandiza kukhala ndi chithunzi chabwino. Mankhwalawa adagwiritsidwa ntchito pazovomerezeka za dokotala pakuthandizira msana, womwe umachitika kumbuyo kwanga kwa osteochondrosis a msana wa lumbar. Nditalandira chithandizo chamankhwala, ndinamva kusintha. Zowopsa za radiculitis sizinawoneke.

Kuyanjana kwa mankhwala osokoneza bongo

• thiamine: imachitika kuwonongeka kwathunthu mu mayankho omwe amakhala ndi sulfite pamaso pa zinthu zamatumbo a B₁ mavitamini ena sanapangidwe, amathandizira kuwonongeka kwa mkuwa wa thiamine, ndikuwonjezereka kwa pH (kuposa 3), thiamine imataya zotsatira zake,
• pyridoxine: m'matenda a Parkinson imathandizira decarboxylation ya levodopa mu minofu, yomwe imapangitsa kutsika kwake,
• vitamini b₁₂: yosagwirizana ndi zamankhwala amchere ndi ascorbic acid,
• lidocaine: ikaphatikizidwa ndi epinephrine ndi norepinephrine, zotsatira zoyipa pamtima zimatha kukula.

Mtengo wa Trigamm mu mafakisi

Mtengo woyenerera wa njira ya Trigamma ya jakisoni wamkati pakiti imodzi ya 5 ampoules a 2 ml ndi ma ruble 117.

Maphunziro: Yoyamba University State Medical University yotchedwa I.M. Sechenov, wapadera "General Medicine".

Zambiri zokhudzana ndi mankhwalawa ndizofanana, zimaperekedwa pazidziwitso ndipo sizilowa m'malo mwa malangizo ovomerezeka. Kudzipatsa nokha mankhwala kuopsa!

Mankhwala ambiri poyamba anali ogulitsidwa ngati mankhwala osokoneza bongo. Mwachitsanzo, a heroin adagulitsidwa ngati mankhwala a chifuwa. Ndipo cocaine adalimbikitsidwa ndi madokotala ngati opaleshoni komanso ngati njira yowonjezerera kupirira.

Vibrator woyamba adapangidwa m'zaka za zana la 19. Adagwira ntchito pa injini yankhonya ndipo adapangira kuti azitsatira khungu la akazi.

Magazi a anthu "amayenda" kudzera m'matumbo omwe akukakamizidwa kwambiri, ndipo ngati umphumphu wake waphwanyidwa, amatha kuwombera mpaka 10 metres.

Asayansi ochokera ku Oxford University adachita kafukufuku wambiri, pomwe adazindikira kuti zamasamba zimatha kuvulaza ubongo wa munthu, chifukwa zimapangitsa kuti kuchuluka kwake kuzikhala kochepa. Chifukwa chake, asayansi amalimbikitsa kuti asachotsere konse nsomba ndi nyama muzakudya zawo.

Malinga ndi kafukufuku, azimayi omwe amamwa magalasi angapo a mowa kapena vinyo mlungu uliwonse ali ndi chiopsezo chowonjezereka cha khansa ya m'mawere.

Pali ma syndromes osangalatsa kwambiri azachipatala, monga kuphatikiza zinthu. M'mimba mwa wodwala m'modzi wodwala mania uyu, zinthu 2500 zakunja zidapezeka.

Ngakhale mtima wa munthu sugunda, akhoza kukhalabe ndi moyo nthawi yayitali, monga asodzi aku Norweji a Jan Revsdal. "Galimoto" yake idayima kwa maola 4 asodzi atasowa ndikugona mu chisanu.

Ntchito yomwe munthu samakonda imakhala yovulaza psyche yake kuposa kusowa kwa ntchito konse.

Kuti tinene ngakhale mawu afupi komanso osavuta, timagwiritsa ntchito minofu 72.

Amayi ambiri amatha kusangalala mwakuganizira za thupi lawo lokongola pakalilore kuposa kugonana.Chifukwa chake, akazi, yesetsani kuyanjana.

Mankhwala akutsokomola "Terpincode" ndi amodzi mwa atsogoleri ogulitsa, ayi chifukwa cha mankhwala ake.

Nthawi yayitali yotsala ndiyotsika ndi yoyipa.

Madokotala a mano adapezeka posachedwa. Kalelo m'zaka za zana la 19, inali ntchito ya tsitsi wamba kuti akatulutse mano odwala.

Asayansi aku America adayesera mbewa ndipo adati madzi ammadzi amaletsa kukula kwa atherosulinosis yamitsempha yamagazi. Gulu limodzi la mbewa limamwa madzi am'madzi, ndipo lachiwiri ndi madzi a mavwende. Zotsatira zake, zombo za gulu lachiwiri sizinali zama cholesterol.

Mu 5% ya odwala, antidepressant clomipramine amayambitsa orgasm.

Chiwerengero cha ogwira ntchito muofesi chakwera kwambiri. Izi zikuchitika makamaka m'mizinda yayikulu. Ntchito yamaofesi imakopa amuna ndi akazi.