Mankhwala Toxivenol - hemostatic wothandizila, angioprotector, mankhwala omwe amachepetsa kuvunda kwa capillary.
Kuphatikiza kwamphamvu kwambiri kwa zigawo za troxerutin ndi carbazochrome kumatsimikizira kuchuluka kwa mapiritsi a mankhwalawa, omwe amalola chithandizo cha matenda a mtima komanso ma syndromes otulutsa magazi ndi kufooka kwa capillary.
Troxerutin, yemwe amadziwikanso kuti Vitamin P4, ndi bioflavonoid yomwe imathandizira kukana kwamitsempha (zoteteza mtima) komanso kuchepetsa kupezekanso, kuteteza kulowa mkati mwa gawo lamwazi m'magazi (zotsatira za kutsekeka ndi kutsika). Kupanga kwamankhwala kumapangitsanso kuwonjezeka kwa Vitamini C, komwe kumapangitsa chitetezo cha membrane kukhathamiritsa komanso kukakamiza kwa hyaluron, komwe, kukakonzedwa, kumatulutsa hyaluronic acid, mucopolysaccharide yomwe imayambitsa kuchuluka kwa mitsempha yamagazi. Kuphatikiza apo, pali kuchepa kwa kumasulidwa kwa histamine, chinthu chopangira vasodilator ndi edema.
Carbazochrome - orthoquinone, mankhwala a adrenaline oxidation popanda ntchito ya sympathomimetic chifukwa chosapezeka kwa gulu lachiwiri la amine ndi gulu la o-diphenol. A vasoconstrictive kwanuko zazingʻono ziwiya zotaya magazi zimakhudza kuchepa kwa magazi. Izi zimachitika popanda kuwonjezeka kuthamanga kwa magazi komanso kukhudza ntchito zamtima. Zinawululidwa kuti carbazochrome imakhudza bwino mphamvu ndi kupenyerera kwa ma capillaries, komanso kamvekedwe ka mphamvu ya magazi.

Zisonyezero zogwiritsidwa ntchito:
Zisonyezero zamankhwala Toxivenol ndi:
- aakulu venous kusowa, varicose mitsempha, wapamwamba thrombophlebitis, zotumphukira, zoopsa pambuyo edema, hematomas, trophic matenda aakulu venous kusowa, dermatitis, trophic zilonda
- zotupa m'mimba
- matenda ashuga,
- retinopathy.

Njira yogwiritsira ntchito:
Mlingo komanso mankhwala Toxivenol payekha: mapiritsi a 2-4 patsiku.

Zotsatira zoyipa:
Mwambiri, mankhwalawa Toxivenol kulekerera bwino, zovuta zimachitika nthawi zambiri zimakhala zofatsa komanso zosakhalitsa. Si kawirikawiri mawonekedwe a kudzimbidwa.

Zoyipa:
Contraindrate kuti agwiritse ntchito Toxivenol ndi chidwi chowonjezeka cha zigawo za mankhwala.

Mimba
Mankhwala Toxivenol Iwo ali osavomerezeka kuti azigwiritsa ntchito panthawi yoyembekezera komanso mkaka wa m`mawere.

Mogwirizana ndi mankhwala ena:
Toxivenol timapitiriza mphamvu ya ascorbic acid pa kapangidwe ndi kupendekera kwa mtima khoma.

Bongo
Palibe zizindikiro za mankhwala opangika kapena osokoneza bongo omwe adadziwika. Toxivenol.
Ngati bongo, mankhwala opatsirana.

Malo osungirako:
Sungani pamalo owuma osafikirika ndi ana pa kutentha kosaposa 25 ° C.

Kutulutsa Fomu:
Toxivenol - tzokutira zokutira.
Mapiritsi 10 pachimake.
Matumphu atatu ndi tsamba lamakalata pabokosi lamakalata.

Zopangidwa:
Piritsi 1 yokutidwaToxivenol Muli zinthu zothandiza: troxerutin 300 mg, carbazochrome 3 mg.
Omwe amathandizira: gamu arabic, wowuma chimanga, talc, povidone, colloidal silicon dioxide, magnesium stearate.
Mapangidwe a Shell: titanium dioxide, calcium carbonate, kaolin, lalanje wachikuda S (E 110), sodium indigo disulfonate (E132), sucrose.

Kufotokozera mtundu wa mankhwala, zikuchokera

Makapisozi a Troxevasin ndi acylindrical komanso achikaso, utoto woyera umakhala mkati. Chofunikira chachikulu pa mankhwalawa ndi troxerutin, zomwe zili mu 1 kapisozi ndi 300 mg. Komanso, momwe zimapangidwira zimaphatikizapo zinthu zothandiza, zomwe zimaphatikizapo:

• Titanium dioxide
• Magnesium wakuba.
• Utoto.
• Lactose Monohydrate.

Makapisozi a Troxevasin amawaika mu paketi yolumikizira zidutswa 10. Phukusi la makatoni amakhala ndi matuza 5 kapena 10 okhala ndi makapisozi, komanso malangizo ogwiritsira ntchito.

Zotsatira za Pharmacokinetics

Chosakaniza chachikulu cha Troxevasin troxerutin kapisozi kamakhala ndi mankhwala osakanikirana a rutin. Ndi mitundu ya Vitamini P yogwira ndipo ali ndi zovuta zingapo zochizira, zomwe zimaphatikizapo:

• Mphamvu ya venotonic - kamvekedwe kachulukidwe ka zotengera zama venous.
• Angioprotective zotsatira - kuteteza mitsempha kuti isawononge zotsatira zoyipa zamafuta angapo.
• Kulimbikitsa makoma a capillaries (zotengera za microvasculature).
• Kuchepetsa kuwonongeka kwa minofu edema, kupsinjika ndi kuchepa kwa mphamvu ya makoma a ziwiya ndi kutulutsa kwa plasma m'zinthu zowonjezera.
• Kupewa mapangidwe intravascular magazi kuundana.
• Kupititsa patsogolo kayendedwe ka magazi popanga kuwonongeka kwa mtima wa khoma la mtima.

Pambuyo potenga kapisolo wa Troxevasin mkatikati, chophatikizacho chimagwira mwachangu ndipo chimafalikira kwathunthu mu kayendedwe kazinthu. Imagawidwanso mokwanira mu minofu, pomwe imayikiridwa mu metabolism ndipo imakhala ndi zotsatira zochizira.

Zizindikiro zogwiritsidwa ntchito

Kulandila kwa makapisozi a Troxevasin akuwonetsedwa pazinthu zosiyanasiyana zamatenda, limodzi ndi kuphwanya magwiridwe antchito a ziwiya ndi kamvekedwe ka mitsempha, monga:

• Matenda a venous osakwanira.
• Matenda a Varicose, limodzi ndi zovuta za trophic.
• Zilonda zam'mimba za pakhungu ndi minyewa yofewa ya magwero osiyanasiyana, zomwe zimachitika chifukwa cha kusayenda kwa magazi ndi mwanabele.
• Postphlebitic syndrome ndi chizindikiro chachikulu chomwe chimayamba pambuyo kutupa m'mitsempha yama venous.
• Ma hemorrhoids - kuwonongeka kwa venous plexus ya gawo loyambira la rectal khoma.
• Retinopathy (kuwonongeka kwammbuyo) mu matenda a shuga, matenda oopsa, matenda oopsa.
• Chithandizo chothandizira cha vutoli mutachotsa mitsempha ndi ma node a varicose.

Komanso, mankhwalawa amagwiritsidwa ntchito pochiza mitsempha ya varicose kapena zotupa m'mimba mwa amayi kumapeto kwa mimba.

Contraindication

Kutenga makapisozi a Troxevasin amatsutsana m'njira zingapo za thupi ndi zolimbitsa thupi, zomwe zimaphatikizapo:

• Kusalolera payekha pazinthu zilizonse za mankhwala.
• Zilonda zam'mimba mu gawo lazachipatala ndi labotale yowonjezera ndi kutengera kwa mucosal chilema m'mimba kapena duodenum.
• Matenda gastritis (kutupa m'mimba) pachimake.
• Mimba mu trimester yoyamba ya maphunzirowa.

Mosamala, mankhwalawa amagwiritsidwa ntchito mwa ana a zaka 3 mpaka 15, komanso kwa anthu omwe ali ndi vuto lofanana ndi impso. Musanatenge ma kapisozi a Troxevasin, ndikofunikira kuonetsetsa kuti palibe zotsutsana.

Kugwiritsa ntchito moyenera

Makapisozi a Troxevasin ndi oyendetsa pakamwa (makonzedwe a pakamwa). Ndimawatenga ndi chakudya, osafuna kutafuna ndikumwa madzi ambiri. Mlingo woyambirira wa mankhwalawa ndi 300 mg (1 kapisozi) katatu patsiku. Achire achire nthawi zambiri amakula patatha masabata awiri atayamba mankhwalawa. M'tsogolo, ngati kuli kotheka, amasinthana ndi kusintha kwa 1 kapisozi 2 kawiri patsiku kapena kuletsa mankhwalawo. Kutalika kwa mankhwalawa kumatsimikiziridwa payekha ndi dokotala wopita.

Zotsatira zoyipa

Kutengera komwe kumatenga mapiritsi a Troxevasin, zotsatira zoyipa zamagetsi m'magazi zingayambike. Izi zimaphatikizapo nseru, kutentha pa chifuwa, chimbudzi (kutsegula m'mimba), kuwonongeka kwa mapangidwe am'mimba. Nthawi zina kumatha kumva kuti “ukuwala” pakhungu la nkhope, kuzizira pakhungu, kuyabwa kwake, komanso mutu. Ngati pali zizindikiro za zoyipa, muyenera kusiya kumwa makapisozi a Troxevasin ndi kufunsa dokotala.

Mawonekedwe akugwiritsidwa ntchito

Asanatenge makapisozi, Troxevasin ayenera kuwerenga mosamala malangizo a mankhwalawa ndikuwunika magwiridwe ake angapo ogwiritsira ntchito, omwe amaphatikizapo:

• Zodalirika zokhudzana ndi chitetezo cha mankhwalawa kwa ana osakwana zaka 15 sizipezeka lero, chifukwa chake, mankhwalawa ayenera kugwiritsidwa ntchito mosamala.
• Ngati, motsutsana ndi kagwiritsidwe ntchito ka mankhwalawa, kuuma kwa zizindikiro za pathological sikuchepa, ndiye kuti kaphatikizidwe kamayenera kusiyidwa ndikuyang'ana kwa dokotala.
• Kugwiritsa ntchito mankhwalawa mu II ndi III trimester yokhala ndi pakati, komanso pa nthawi yoyamwitsa, ndikuloledwa kuti phindu lomwe mayi akuyembekeza limayang'ana ku chiwopsezo cha mwana wosabadwayo kapena khanda.
• Mphamvu ya mankhwalawa imatheka ndikugwiritsa ntchito munthawi yomweyo ndi ascorbic acid (vitamini C).
• Gawo lomwe limagwiritsa ntchito mankhwalawa silikhudza mwachangu kuthamanga kwa ma psychomotor, komanso kuthekera kwambiri.

Pamaukonde apachipatala, makapu amtundu wa Troxevasin amaperekedwa popanda kulandira mankhwala. Ngati mukukayika pakugwiritsa ntchito mankhwalawa moyenera, dokotala.

TOXIVENOL

• Pharmacokinetics
• Zizindikiro zogwiritsidwa ntchito
• Njira yogwiritsira ntchito
• Zotsatira zoyipa
• Contraindication
• Mimba
• Kuchita ndi mankhwala ena
• Malo osungira
• Kutulutsa Fomu
• Kupanga
• Zosankha

Toxivenol - angioprotector, mankhwala omwe amachepetsa kuvunda kwa capillary.
The kuchuluka kwa carbazochrom mu madzi am'madzi amapezeka mphindi 10 atatha kugwiritsa ntchito, pafupifupi kuchuluka kwa ndende ya m'magazi (Cmax) ndi 21.0 ± 8.4 ng / ml, ndipo nthawi yakufika pachimake ndi Tmax ndi maora a 1.2 ± 0,5. T1 / 2, nthawi yayitali yosungirako (VCA) ndi dera lomwe likuzunguliridwa ndi maola 2 mpaka maola 8 ndi maola a 2,5 ± 0.9, 4.1 ± 1.1 maola ndi 65.9 ± 25.3 h ng / m, motsatana.
Kuphatikiza kwabwino kwambiri kwa zigawo za troxerutin ndi carbazochrome kumatsimikizira kuchuluka kwa mapiritsi a mankhwalawa, omwe angalole chithandizo cha matenda a mtima komanso ma syndromes otulutsa magazi ndi kufooka kwakukulu kwa capillaries.
Troxerutin ali ndi ntchito ya P - vitamini, amawonetsera kutulutsa zinthu zamkati, kubwezeretsa kuvunda kwamatumbo osungunuka, kumachepetsa kufooka, kutsimikizira kusasinthika, kulimba mtima ndi kukana kuvulala koopsa.
Kupanga kwamankhwala kumapangitsa kuchuluka kwa vitamini C, komwe kumapangitsa ntchito yoteteza kuphatikizidwa kwa membrane ndi kukakamiza kwa hyaluron, komwe, kukakonzedwa, kumapanga hyaluronic acid - mucopolysaccharide, yomwe imayambitsa kuwuma kwamitsempha yamagazi. Kuphatikiza apo, pali kuchepa kwa kumasulidwa kwa histamine, chinthu chopangira vasodilator ndi edema.
Carbazochrome - orthoquinone, mankhwala a adrenaline oxidation popanda ntchito ya sympathomimetic chifukwa chosapezeka kwa gulu lachiwiri la amine ndi o - diphenol gulu. A vasoconstrictive kwanuko zazingʻono ziwiya zotaya magazi zimakhudza kuchepa kwa magazi. Izi zimachitika popanda kuwonjezeka kuthamanga kwa magazi komanso kukhudza ntchito zamtima. Zinawululidwa kuti carbazochrome imakhudza bwino mphamvu ndi kupenyerera kwa ma capillaries, komanso kamvekedwe ka mphamvu ya magazi.

Pharmacokinetics

Pambuyo pakamwa, troxerutin imatengedwa mwachangu kuchokera m'mimba. Mkulu pazambiri (Cmax) wa troxerutin m'madzi am'magazi amafikira pambuyo pa ola limodzi ndipo ndi 81.00 ± 2.94 ng / ml, theka lamoyo (T0.5) ndi maola 8, 73 ± 0.88.
Kulumikiza kumapuloteni a plasma kuli pafupifupi 30%. Amapukusidwa mu chiwindi kuti aglucogonic mitundu ya mono-, di - ndi trihydroxyethylrutosides, glucurinides ndi zotumphukira za aryl acetic acid. Kutha kwa theka moyo kumasiyana 10 - 25 maola. Amayikamo mkodzo pafupifupi 25%, ndi bile - pafupifupi 70%.

Njira yogwiritsira ntchito

Mapiritsi Toxivenol kumwa mkamwa.
Kumayambiriro kwa mankhwalawa, imwani piritsi limodzi katatu patsiku.
Zizindikiro zopweteka zimatha patatha milungu iwiri.
Ndikulimbikitsidwa kuti mulingo womwewo athandizidwe mpaka zizindikiratu.
Chithandizo cha kukonzekera: piritsi 1 patsiku kwa masabata 3-4.
Mlingo wa tsiku ndi tsiku ndi 600 mg (piritsi 1 kawiri pa tsiku).
Mlingo wapamwamba tsiku lililonse ndi 900 mg (piritsi 1 katatu patsiku).

Kutulutsa Fomu

Mapiritsi a Toxivenol.
Mapiritsi 10 pa khungu lililonse. Pamiyala itatu ya cell yolumikizana pake.

Piritsi 1Toxivenol Muli zinthu zothandiza: troxerutin 300 mg, carbazochrome 3 mg.
Othandizira: Chamu cha Arabia, chimeza chowala, peyala, povidone, colloidal silicon dioxide, magnesium stearate.
Mapangidwe a Shell: titanium dioxide (E171), calcium carbonate, kaolin, utoto wa utoto - chikasu S (E 110), utoto wa indigotine (E132) (sodium indigo disulfonate), sucrose.

Dzinalo Lopanda Padziko Lonse

INN, gulu la mankhwalawo ndi Troxerutin.

Troxevenol ndi mankhwala othandiza kugwiritsa ntchito ziwindi, zomwe zimatanthauzira othandizira othandizira.

Khodi ya ATX ndi C05CA54 (Troxerutin ndi kuphatikiza).

Kutulutsa mafomu ndi kapangidwe kake

Mankhwala amapezeka mu mawonekedwe a gel. Imakhala ndi mtundu wachikasu wobiriwira kapena wachikasu ndipo sikhala ndi fungo labwino.

Gelali imayikidwa mu machubu a zotayidwa ndi voliyumu ya 40 g, yomwe ili pakatoni. Kukonzekera kumayendetsedwa ndi malangizo apepala.

Mapangidwe a Troxevenol akuphatikiza zinthu zomwe zimagwira ntchito:

• troxerutin (20 mg),
• indomethacin (30 mg),
• ethanol 96%,
• propylene glycol
• methyl parahydroxybenzoate (E 218),
• carbomer 940,
• macrogol 400.

Zotsatira za pharmacological

Zosakaniza zogwiritsidwa ntchito za mankhwala ndi indomethacin ndi troxerutin. Amakhala ndi kukhazikika, analgesic, anti-kutupa komanso kupatsa mphamvu kwambiri. Izi zimatheka chifukwa chopinga cha kuphatikizika kwa prostaglandin kudzera mu kusintha kwa COX blockade ndi kulepheretsa kwa kuphatikiza kwa maselo ambiri.

Mankhwalawa amathandizira kuchepetsa kutupa ndi kupweteka m'miyendo, kumatha mphamvu ya veniconic komanso kumachepetsa kupezekanso kwa capillaries.

Mankhwalawa amathandizira kuchepetsa ululu m'miyendo.

Momwe mungatenge Troxevenol

Gilal imayikidwa mu wochepa thupi pazidutsazo pogwiritsa ntchito massaging 2-5 patsiku. Mlingo wa tsiku ndi tsiku sayenera kupitirira 20. Kutalika kwa mankhwalawa kuyambira 3 mpaka masiku 10.

Gilal imayikidwa mu wochepa thupi pazidutsazo pogwiritsa ntchito massaging 2-5 patsiku.

Zokhudza mphamvu pakuwongolera njira

Mankhwalawa samakhudza kuyendetsa galimoto komanso njira zina zovuta.

Nthawi zina, mankhwalawa amatha kuyambitsa zovuta pakhungu ndi kuyabwa.
Nthawi zina, mankhwalawa angayambitse matenda amtundu wa bronchial.
Nthawi zina, mankhwalawa amatha kuyambitsa mavuto obwera chifukwa cha mseru komanso kusanza.
Nthawi zina, mankhwalawa amatha kuyambitsa zovuta mmatumbo.

Malangizo apadera

Gelalo limapangidwa kuti lizigwiritsidwa ntchito kunja kokha. Sizoletsedwa kuti zizitenga mkati.

Ngati mwangozi malowedwe a mankhwala m'maso, muzimutsuka yomweyo ndi madzi. Ngati ilowa mkamwa kapena m'mimba, kukomoka kwa m'mimba kuyenera kuchitidwa.

Formula ya leukocyte ndi mapulateleti amayenera kutsimikizika ngati chithandizo chikuchitika masiku opitilira 10.

Chochita chitha kupakidwa pakhungu lokhazikika. Pewani kulumikizana ndi mabala otseguka.

Pamaso pa zilonda zam'mimba, mankhwalawa ayenera kugwiritsidwa ntchito mosamala kwambiri.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Mankhwala amaletsedwa kugwiritsa ntchito mu trimester yoyamba ya kutenga pakati. Nthawi ya II ndi III trimester, mankhwalawa amayenera kulembedwa pokhapokha pakufunika kwambiri, pomwe phindu lomwe lingapose chiwopsezo kwa mayi ndi mwana wosabadwayo.

Nthawi ya II ndi III trimester, mankhwalawa ayenera kuyikidwa pokhapokha pakufunika kwambiri.

Amayi omwe akuyamwitsa amatsutsana pogwiritsa ntchito mankhwalawa, chifukwa amamwa mkaka. Pamaso pazinthu zomwe zikufunika kugwiritsa ntchito Troxevenol, kuyamwitsa kuyenera kuyimitsidwa kwathunthu kwa nthawi yamankhwala.

Kuchita ndi mankhwala ena

Osavomerezeka kuti agwiritse ntchito mankhwalawa molumikizana ndi mankhwala osapweteka a antiidal (amatha kuyambitsa zotsatira) ndi corticosteroids (amatha kupangitsa ulcerogenic athari).

Sikulimbikitsidwa kugwiritsa ntchito mankhwalawa molumikizana ndi mankhwala osapweteka a antiidal.

Kuyenderana ndi mowa

Sizoletsedwa kumwa zakumwa zoledzeretsa mukamalandira mankhwala ndi Troxevenol. Kuphwanya lamulo loletsa ntchitoyo kumatha kupangitsa kuti musamadandaule komanso kuti muchepetse mphamvu ya mankhwala.

Mankhwalawa ali ndi mayendedwe ofanana ndi omwe:

• Ascorutin (fomu yotulutsa - mapiritsi, mtengo wapakati - 75 ma ruble),
• Anavenol (akupezeka mu mawonekedwe a piritsi, mtengo umasiyanasiyana kuchoka pa 68 mpaka 995 rubles),
• Venorutinol (mafomu omasulira - makapisozi ndi ma gel, mtengo wamba ndi ma ruble 450),
• Troxevasin (mawonekedwe omasulira - mafuta, mtengo umachokera ku 78 mpaka 272 rubles),
• Diovenor (wopezeka mu mawonekedwe a piritsi, mtengo - kuchokera pa 315 mpaka 330 rubles).

Kusankha kwa analogue kuyenera kuchitika ndi dokotala, ndizoletsedwa kuti muzichita nokha.

Malangizo a Ascorutin Troxevasin: ntchito, mawonekedwe omasulira, mavuto, analogues

Wopanga

Amapangidwa ku Russia ndi Samaramedprom OJSC.

Tatyana, wazaka 57, Irkutsk: "Ndakhala ndikuvutika ndi mitsempha ya varicose kwa nthawi yayitali. Kwa zaka 4 tsopano, misempha yanga ikaipiraipira, ndakhala ndikugwiritsa ntchito Troxevenol. Imachepetsa kupsinjika, kupweteka komanso kuchepetsa kutupa."

Ulyana, wazaka 46, ku Moscow: "Ndinachotsa zotupa m'mimba mothandizidwa ndi Troxevenol. Ndinapita kwa dotolo atangoona kaye matendawa atangoyamba kumene. Anamuwuza kuti apatsidwe mankhwala ngati mankhwalawo. Ndinaugwiritsa ntchito kwa masiku 10. Panthawi imeneyi, ululu ndi kutupa zinatheratu. Kwa zaka 2, matendawa sanabwerenso. "

Natalia, wazaka 33, Sochi: "Nditabereka, mitsempha ya varicose idawonekera. Ndidayesa mankhwala osiyanasiyana apakhungu koma sizinathandize. Mwanjira ina ndinamva kwa mzanga za Troxevenol ndipo ndinaganiza zogula mankhwala. Zotsatira zake zimaposa zomwe tinkayembekezera: kutupa, kupweteka komanso kulemera miyendo inatheratu, ndipo ma venous network adayamba kutchulidwa. Tsopano ndimagwiritsa ntchito mankhwalawa kwa masiku 7 katatu pachaka zizindikilo za matendawa zikayamba kuvuta. "

Larisa, wazaka 62, ku St. Petersburg: "Ndimadwala matenda a shuga. Timakonda kupulumuka zilonda zam'mimba mothandizidwa ndi Troxevenol. Amathandizira kupweteketsa ululu, kuwotcha, kumalimbikitsa machiritso okhazikika ndipo samasiya mabala atangochira."

Gel yani

Zochizira mitsempha ya varicose ndi zina zokhudzana ndi pathological, madokotala amalimbikitsa mankhwala a Troxevenol gel. Malangizo ogwiritsira ntchito mankhwala akunja awa amafotokozera mphamvu yake ngati angioprotective ndi tonic.

Ili ndi mtundu umodzi, mtundu wake ndi wachikaso.

Pharmacodynamics ndi pharmacokinetics

Kupanga kwamatenda mphamvu ya Troxevenol ndi chifukwa cha kukhalapo kwa zinthu ziwiri zogwira - indomethacin ndi troxerutin.

Indomethacin imatulutsa odana ndi yotupa komanso yamphamvu kwambiri, imachepetsa ululu. Kuchita kwa thunthu ndi kutengera luso lake lolepheretsa kuphatikiza kwa ma prostaglandins pobwezeretsa blockade ya enzime ya COX.

Zimalepheretsa kumamatira m'matumba a mitsempha yamagazi ndikumangika gluing pamodzi. Pogwiritsa ntchito zakunja kwawoko, mankhwalawo amachepetsa ululu ndi kutupa, amachepetsa nthawi yobwezeretsa mphamvu zamagalimoto povulala ndi machitidwe a minofu.

Poyerekeza ndi salicylates ndi phenylbutazone, imakhala ndi mphamvu zotsutsana ndi kutupa.

Troxerutin ndi wa bioflavonoids, ndi mankhwala osakanikirana a rutoside. Imawonetsa capillar -oteteza, antioxidant, vasoconstrictive kanthu. Imachepetsa kupenyerera kwa capillary ndi mitsempha yamatumbo.

Amachotsa vasodilation chifukwa cha zotsatira za histamine, bradykinin ndi acetylcholine. Amatsuka puffness ndi kusintha trophism ndi zowawa mawonetseredwe opweteka a venous kusakwanira.

Imachepetsa kutupa kwamakoma a mitsempha yamagazi ndikulepheretsa kudziphatikiza kwa mapulateleti kwa iwo.

Mawonekedwe a gel amaloleza kuti zigawo zikuluzikulu zigwire mkati mwa minyewa yovunda komanso madzimadzi okhathamira. The bioavailability wa indomethacin ndi 90%, kagayidwe kumachitika mu chiwindi ndi mapangidwe ophatikizika mankhwala. Amayikamo mkodzo, ndulu ndi ndowe. Imatha kulowa mkaka wa m'mawere.

Troxerutin amathandizidwa ndi impso.

Amawonetsedwa pakuchizira kovuta kwa venous insufficiency ndi varicose mitsempha, komanso machitidwe amkati ndi kuvulala.

Kugwiritsa ntchito popanda thrombophlebitis, phlebitis ndipo pambuyo phlebitis, zotupa, tendovaginitis, fibrositis, bursitis, periarthritis.

Mu nthawi yogwira ntchito, imasinthidwa kuti muchepetse edema ndikubwezeretsa kulimba kwa miyendo.

Chidacho chimathandizira kuchepetsa kutupa ndikuchotsa kutupa pambuyo pa kuphulika, kusamuka, kupopera.

Muubwana, panthawi yoyembekezera komanso HB

Troxevenol sanadutse mayeso odalirika azachipatala, chifukwa chake sichilembedwera ana osakwana zaka 14 ndi amayi apakati omwe ali ndi trimester yoyamba kubereka.

Pakadutsa nthawi yokhala ndi pakati komanso poyamwitsa, mankhwalawa amagwiritsidwa ntchito mosamala, kuwunika kuchuluka kwa chithandizo chomwe chikuyembekezeka chimaposa zoopsa zomwe zingachitike kwa mwana.

Zotsatira zoyipa

Anthu ambiri amalekerera mankhwalawo ndipo samakumana ndi zovuta zina.

Nthawi zambiri, odwala amakumana ndi zimachitika mdera - kufupika kwa khungu pamalo ogwiritsira ntchito gel, kuyabwa ndi kuyaka, kumva kutentha ndi kumva kutentha.

Mphamvu zimachitika pakapita nthawi yayitali, osagwiritsa ntchito mankhwalawa. Kuchokera m'mimba, mumakhala kupweteka m'mimba ndi epigastric dera, mseru komanso kusanza, kugona. Hepatic transaminases imachuluka.

Chitetezo cha mthupi chimatha kupereka mayankho osagwirizana ndi zizindikiro za kuchuluka kwa chidwi. Mankhwala a anaphylactic, kuwukira kwa mphumu, angioedema ndi osowa kwambiri.

Kuphatikizika kwa mankhwalawa kumakhala ndi propylene glycol, yomwe imakwiyitsa khungu komanso E218, yomwe ingayambitse ziwengo.

Bongo

Pogwiritsa ntchito bwino mankhwala, bongo osatheka. Ngati nthawi ya maphunzirowa yapita ndipo njira zake zonse zimawonedwa, amasiya kugwiritsa ntchito mankhwalawo ndikuchita mankhwalawa.

Ili ndi ma fanizo ambiri okhala ndi chinthu chimodzi chogwira ntchito:

Mitengo ya mankhwalawa imasiyana pang'ono, ndipo zimatengera wopanga.

Ogulitsa ndi analogue yathunthu yophatikizika ya troxerutin + indomethacin. Mankhwalawa amatchedwa Indovazin, mtengo wake umachokera ku ma ruble 270-350.

Kuphatikiza komweku kwa zinthu zogwira ntchito kulipo mu mankhwala a Troximethacin, mtengo womwe mumasitolo amapanga ma 150-200 rubles.