Momwe mungagwiritsire ntchito Metformin Canon?

Mankhwalawa amapezeka ngati mapiritsi okhala ndi mafilimu. Pali mapiritsi okhala ndi 500 mg, 850 mg ndi 1000 mg ya metformin.

Mapiritsi okhala ndi Mlingo wa 500 mg ndi ozungulira, ndipo mapiritsi okhala ndi 850 mg ndi 1000 mg (Metformin yayitali) ndi owonda.

Mankhwalawa amapezeka ngati mapiritsi okhala ndi mafilimu.

1. Metformin hydrochloride.
2. Polyethylene glycol (macrogol).
3. Povidone.
4. Talc.
5. Sodium stearyl fumarate.
6. Wowuma wa sodium carboxymethyl.
7. Wowuma pregelatinized.
8. Opadry II woyera (wopanga kuyimitsidwa).
9. Titanium dioxide.
10. Mowa wa Polyvinyl.

Zotsatira za pharmacological

Metformin imalepheretsa gluconeogeneis, kaphatikizidwe wamafuta amafuta achilengedwe, komanso njira ya lipolysis (kusweka kwamafuta) ndi oxidation wamafuta. Nthawi yomweyo, kumwa kwa glucose mthupi kumayambitsidwa ndikuwonjezera chidwi cha maselo kuti apange insulin.

Mankhwala amateteza zomwe zili ndi triglycerides ndi cholesterol m'magazi. Pali kuchepetsa pang'onopang'ono kwa odwala onenepa kwambiri.

Mankhwala tikulimbikitsidwa pamaso pa thrombosis, chifukwa ali ndi fibrinolytic. Metformin imathandiza kuthetsa ziwalo zamagazi m'mitsempha yamagazi.

Mankhwala tikulimbikitsidwa pamaso pa thrombosis, chifukwa ali ndi fibrinolytic.

Pharmacokinetics

Mukamamwa pakamwa, mankhwalawa amayamba kutengeka pang'onopang'ono kuchokera m'mimba. Mafuta a Metformin ndi 50%. Bioavailability sichidutsa 60%. Zinthu zimafika poizika kwambiri m'madzi am'madzi mkati mwa 2-2,5 maola.

Metformin imangokhala yofooka mpaka kumagazi a albin, koma imalowetsedwa mwachangu ndimadzi achilengedwe. Amadzipatula m'thupi ndi impso makamaka zosasinthika. Nthawi ya excretion ndi maola 8-12.

Kodi limayikidwa kuti?

Mankhwalawa amalembera achikulire ndi ana a zaka zopitilira 10 kuchokera ku kunenepa kwambiri ndi mtundu wa 2 wodwala mellitus (osagwirizana ndi insulin). Mankhwalawa angagwiritsidwe ntchito m'njira zoyambira komanso zachiwiri (kuphatikiza ndi insulin).

Zizindikiro zina zogwiritsidwa ntchito ndi:

1. Mafuta hepatosis (chiwindi dystrophy). Matenda omwe amasintha hepatocytes (ma cell a chiwindi) kukhala minofu ya lipid.
2. Polycystic ovary. Izi matenda nthawi zambiri limodzi ndi kuchuluka insulin kukana. Kupanga kwa mahomoni ambiri ndi kuchuluka kwa shuga m'magazi kumachitika.
3. Hyperlipidemia. Matendawa amadziwika ndi nkhani zambiri za lipids ndi lipoprotein m'magazi.

Chizindikiro chogwiritsidwa ntchito ndi mafuta a hepatosis.

Contraindication

Mankhwala ndi contraindised otsatirawa milandu:

• kusalolera kwa munthu wa metformin kapena woyimira,
• wodwala matenda ashuga
• matenda ashuga
• matenda oopsa a chiwindi
• kuwonongeka kwaimpso,
• kutsegula m'mimba kwambiri kapena kusanza,
• matenda opatsirana opatsirana
• hypoxia
• malungo
• sepsis
• anaphylactic shock,
• myocardial infaration
• kupuma kapena kulephera kwa mtima,
• uchidakwa
• lactic acidosis,
• kuperewera kwa kalori
• zaka za ana mpaka 10.

Kumwa mankhwala a shuga

Malinga ndi malangizo, achikulire omwe ali ndi monotherapy amakhazikitsidwa 1000-1500 mg wa mankhwala patsiku. Ngati ndi kotheka, tsiku lililonse mlingo umakulitsidwa pang'onopang'ono mpaka 2000 mg. Mlingo wapamwamba tsiku lililonse ndi 3000 mg wa metformin. Mlingo wa tsiku ndi tsiku utha kugawidwa mu Mlingo wa 2-3.

Akaphatikizidwa ndi insulin, mlingo wa Metformin ndi 1000-1500 mg patsiku. Pa mankhwala, kusintha kwa insulin kungafunike.

Kodi mungatani kuti muchepetse kunenepa?

Zochizira kunenepa, zomwe zimapangitsa kuti insulin ikane, mankhwalawa ndi mankhwala 500 mg kamodzi. Mlingo ukuwonjezeka 2000 mg pa tsiku, kuwonjezera 500 mg sabata lililonse.

Metformin imathandizira kuchepetsa kulemera pophatikizidwa ndi zakudya zoyenera.

Metformin imathandizira kuchepetsa kulemera pophatikizidwa ndi zakudya zoyenera. Koma kudya mosamalitsa sikungalandiridwe chifukwa choopsa cha hypoglycemia.

Kuchokera kumbali ya kagayidwe

Zokhudza kagayidwe:

• lactic acidosis,
• Kuperewera kwa B12 (kuvulala kwam'mimba kwa vitamini).

Malangizo apadera

Pamaso ntchito ndi mayeso ntchito radiopaque zinthu, mankhwala anathetsa. Kuchotsa mankhwala kumachitika masiku awiri asanafike mayeso ndipo amayambiranso pambuyo pa masiku awiri.

Pamaso pa opareshoni, mankhwala amaletsedwa.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Popeza chinthu chodutsacho chimadutsa placenta, amayi apakati saloledwa kumwa mankhwalawa. Maphunziro odalirika a teratogenic zotsatira za metformin sanachitike. Nthawi zina madokotala amapereka mankhwala kwa amayi apakati ngati pakufunika.

Kuyamwitsa panthawi ya chithandizo ndikulimbikitsidwa kuti uyime.

The ntchito aimpso kuwonongeka

Kuchita ndi mankhwala ena

Mankhwala amatengedwa mosamala ndi mankhwala otsatirawa:

1. Danazole (wothandizira hyperglycemic).
2. Chlorpromazine.
3. Ma antipsychotic.
4. Zothandiza kuchokera ku sulfonylureas.
5. NSAIDs.
6. Oxytetracycline.
7. ACE zoletsa ndi Mao.
8. Zovala.
9. Mankhwala a Hormonal (kuphatikiza kulera kwa pakamwa).
10. Ma diuretics (ochokera pagulu la thiazide kapena loop diuretics).
11. Amachokera ku nicotinic acid ndi phenothiazine.
12. Glucagon.
13. Cimetidine.

Ngati kuphatikiza koteroko ndikofunikira, adokotala amasintha muyeso wa mankhwalawo ndikuwongolera kuchuluka kwa shuga ndi lactic acid m'magazi.

Kuyenderana ndi mowa

Izi sizigwirizana ndi mowa. Mowa umawonjezera chiopsezo cha minofu hypoxia, lactic acidosis ndi zovuta zina.

Ma fanizo odziwika bwino pankhaniyi akuphatikiza Glucophage (Merck Sante, France), Formmetin (Pharmstandard, Russia), Siofor (Berlin-Chemie, France). Mankhwalawa ali ndi chinthu chofanana - metformin hydrochloride.

Mankhwala monga Metformin Teva ndi Metformin Richter ndi ma genetic. Ndizofanana ndi Metformin Canon pamapangidwe ndi zochita, koma amapangidwa ndi ena opanga.

Ndemanga pa Metformin Canon

Konstantin, wazaka 42, St. Petersburg

Ndakhala ndikugwira ntchito ya endocrinologist kwazaka 10. Mankhwalawa amalembedwa kwa odwala matenda a shuga komanso kunenepa kwambiri. Zimathandizira kuteteza kagayidwe kazigawo ndi glucose. Sindimawona zotsatira zoyipa machitidwe anga.

Irina, wazaka 35, Krasnodar

Metformin ndiwothandiza pa matenda a shuga 2. Odwala anga amalekerera bwino mapiritsi awa. Pambuyo mwezi umodzi kumwa magazi madontho. Popewa kupweteka m'mimba, ndikulimbikitsa kuti musamwe mankhwalawa pamimba yopanda kanthu.

Valentine, wazaka 56, Belorechensk

Ndinaphunzira zamankhwala monga Metformin, Siofor, Glucofage kuchokera kwa endocrinologist. Adawalimbikitsa kuti alimbane ndi matenda ashuga. Ubwino wa Metformin poyerekeza ma analogu ndi mtengo wotsika. Mankhwalawa adathandizira ndipo sanayambitse zoyipa.

Alexander, wazaka 43, Volgograd

Ndimamwa mankhwalawa pofuna kupewa matenda ashuga. Shuga wamagazi adayamba kukwera, ndipo adotolo adatcha Metformin. Sindinapeze zovuta zilizonse panthawi ya chithandizo.

Ekaterina, wazaka 27, Moscow

Nditabereka, ndinayamba kuchira msanga. Sindingathe kutsatira zakudya zosafunikira kwa nthawi yayitali, choncho ndidaganiza zoyesa Metformin kuti muchepetse chilakolako cha kudya. Mankhwalawa adathandizira kuchotsa makilogalamu 5 pamwezi. Njala izitota, ndipo sindingadye kwambiri.