Kusiyana pakati pa Orlistat ndi Xenical

Kunenepa kwambiri ndi vuto lalikulu lomwe limatha kukhala vuto la matenda ashuga komanso zovuta zina za metabolic m'thupi. Pankhaniyi, zakudya sizimapereka zotsatira zapamwamba, wodwalayo saganiza ngakhale pang'ono zamaphunziro akuthupi.

Kuti muthandizire kubwera ndi mankhwala omwe angakuthandizeni kuonda kwambiri. Mwa ndalamazi, titha kusiyanitsa Swiss Xenical ndi mnzake wa kunyumba Orlistat.

Orlistat ndi mankhwala omwe amaletsa kuwonongeka kwa mafuta chakudya chikamalowa m'mimba, potero amachotsa zopatsa mphamvu zambiri mwa mawonekedwe a triglycerides kupita kunja. Zotsatira zake, thupi silimadzaza ndi ma calorie otsala ndikuyamba kugwiritsa ntchito mafuta osungidwa, kumawonjezera kuchuluka kwa ndowe m'masiku ochepa a kudya.

The yogwira pophika ndi lipase inhibitor m'mimba ndi matumbo a dzina lomweli - orlistat. Mankhwala amathandizidwa ndi akatswiri azakudya, endocrinologists, gynecologists kwa odwala omwe ali ndi vuto la metabolic komanso matenda a kunenepa kwambiri.

Kuphatikiza ndi kuyang'anira makapisozi a Orlistat, ndikofunikira kuyang'anira njira yonse ya zakudya zopatsa mphamvu, popeza kuchuluka kwamafuta m'zakudya kumadzetsa mawonekedwe.

Kuchepetsa thupi pa mankhwalawa kumathandiza wodwalayo:

• kuwopsa kwa matenda oopsa amachepetsa,
• Mankhwala a shuga amakhala othandiza kwambiri
• lipid metabolism bwino.

Kuchita ndi mankhwala ena

Orlistat imagwiritsidwa ntchito ndi mankhwala ambiri, koma ikatengedwa ndi alpha-tocopherol ndi beta-carotene, amachepetsa kuyamwa kwawo. Ngati wodwala akutenga zina mwazowonjezera izi, ndikofunikira kusintha mlingo wawo kuti atenge Orlistat.

Contraindication

Kumwa mankhwala ali contraindified zotsatirazi:

• kusalolera kwa munthu wogwira ntchito,
• cholestasis
• chimbudzi chovuta.

Mochenjera:

• ubwana
• kukhalapo kwa calculi mu kwamkodzo kapena impso,
• hyperoxaluria.

Panthawi yoyembekezera, adokotala amatha kukupatsirani mankhwala pokhapokha pa udindo wake, chifukwa pakhala palibe kafukufuku pazokhudza Orlistat pa mkazi ndi mwana wosabadwayo.

Mankhwala Orlistat amadzigawika m'magulu azimayi panthawi yomwe akuyembekezera mwana komanso kuyamwa, chifukwa kuwonda kwake kungakhudze kukula kwa mwana wosabadwayo!

Xenical ndi mankhwala omwe amaletsa kuyamwa kwamafuta owonjezera ndi thupi. Zomwe zimagwira pophika ndi orlistat.

Zotsatira zoyambirira za kumwa mankhwalawa zimawonedwa kale pa tsiku la 3 la makonzedwe: wodwalayo amayamba kumva bwino, chifukwa cha kuchoka kwa edema, kuchepa kwa thupi kumachepa. Pulogalamu yogwira, yolowa m'thupi, imalepheretsa kuthana ndi calories m'mafuta ndikuwachotsa kunja, ndikuwononga njira za metabolic. Chifukwa cha izi, kulemera kwa wodwala kumatha, ndipo nthawi zambiri, kumayamba kuchepa pang'onopang'ono.

Mphamvu ya mankhwalawa imawonetsedwa ndi kapangidwe ka metabolites mkati mwa matumbo, omwe samagwira ntchito kwambiri kuposa mankhwala Orlistat. Izi zimapereka gawo laling'ono pamatumbo a m'mimba.

Zizindikiro zogwiritsidwa ntchito

Xenical imafotokozedwa motere:

• kunenepa
• kunenepa kwambiri pamatenda oyamba,
• monga gawo la chithandizo chovuta cha matenda ashuga.

Mankhwalawa amaperekedwa limodzi ndi mankhwala a hypoglycemic, mwachitsanzo, ndi Insulin kapena Metformin.

Kusiyana kwa mankhwala

Akapezeka ndi kunenepa kwambiri kapena kulemera chifukwa cha zovuta za matenda ashuga, madokotala amamulembera Orlistat kapena mnzake Xenical. Ndizosatheka kunena ndendende zomwe zili zoyenera kwa odwala omwe ali ndi kunenepa kwambiri, chifukwa othandizira ali ofanana ndipo ali ndi chinthu chofananira ndikuphatikizidwa.

Mankhwala onse awiriwa amapangidwira kuti azigwiritsa ntchito nthawi yayitali, musawononge thupi.

Kusiyanitsa pakati pa Orlistat ndi Xenical:

• kusiyana kwakukulu ndi mtengo womwe uli m'chigawo cha Russian Federation: Xenical yokhala ndi makapositi 42 ungagulidwe kwa ma ruble 1800, pomwe Orlistat yofanana ndi makapisozi imadya pafupifupi ma ruble 500,
• Malangizo a Xenical akuwonetsa ma contraindication angapo pomwe, ngati wopanga Orlistat, ndikuloledwa kutenga milandu yambiri.

Mwakuchita bwino, onse mankhwalawa amadziwonetsera okha komanso mwachangu.

Ndikofunikira kulingalira za kudya kwina kwa mankhwala ena, popeza kuchiritsa kwa zomwe zimagwira kumatengera izi!

Mwa kuwonetsa kwa zoyipa, Orlistat ndi Xenical zimawonetsa zabwino, zolemba zochepa zoyipa zalembedwa.

Malingaliro a madotolo

Akatswiri ambiri salimbikitsa kumwa mankhwala malinga ndi yogwira mankhwala kapena popanda kuonana ndi dokotala. Mankhwalawa amathandizira pakugwira ntchito kwa ziwalo zamkati, pa lipid metabolism, amakhala ndi zovuta komanso contraindication. Pamaso pa matenda osachiritsika, ndikofunikira kusamala pakumwa mankhwala atsopano, chifukwa kutha kwawo kungapangitse kuchuluka kwa matenda a pathologies.

Nazimova E.V., endocrinologist, Moscow

Xenical ili ndi chiwerengero chochepa chotsutsana ndi zoyipa zomwe sizimagwiritsidwa ntchito moyenera. Cholinga cha mankhwalawa kwa nthawi yayitali chimathandizira kutaya mapaundi owonjezera owerengeka kwa odwala. Ndikofunika kumwa mankhwalawa, kuphatikiza ndi zakudya komanso kumizidwa m'moyo wathanzi.

Panteleimonova O.V., dokotala wazamankhwala, Saransk

Orlistat ndi Xenical ndizofanana pakuchita bwino komanso kuchitapo kanthu kwa mankhwala; Orlistat kwa odwala ambiri ndi njira yoyenera kwambiri yokwanira mtengo. Mankhwala omwe ali m'gulu la ndalama amakhala komwe amakhala ndipo kuyambira tsiku loyamba amalola odwala kuti asathenso kulemera kwambiri.

Ndemanga Zahudwala

Ndemanga zingapo zikuwonetsa kuti Xenical ndi Orlistat ndi ofanana kwambiri pakuchita kwawo.

Catherine, wa zaka 34, Veliky Novgorod

Ndinayamba kunenepa kwambiri nditakwanitsa kubereka kwachiwiri, kupatula ndili ndi matenda a shuga kuyambira ndili mwana. Zakudya sizinathandize kuchepetsa thupi, zimawonedwa ndi madotolo ambiri, mpaka dokotala m'modzi wandipangira makapisozi a Xenical, ndimamwa kwa nthawi yayitali, yomwe ndi miyezi isanu ndi umodzi, munthawi imeneyi ndidataya mapaundi owonjezera asanu. Nthawi yomweyo ndinadya pomwepo, ndinayenda kwambiri ndi wopalasa. Sindinamve zowawa zilizonse, koma ndilibe matenda a pathologies.

Nina, wazaka 24, St. Petersburg

Saw Xenical 1.5 zaka, nthawi imeneyi adaponya 15 mapaundi. Anayamba kulemera pachikhalidwe cha matenda ashuga a 2. Anatenga Xenical limodzi ndi insulin, kudya komanso kuchita masewera olimbitsa thupi. Ndinakhutitsidwa ndi momwe mankhwalawo adakhazikitsira mpaka ndidapeza chiwonetsero chotsika mtengo, chakunyumba - Orlistat, chosinthidwa kuchokera ku Ksenikal kupita kwa icho ndipo sanamve kusiyana kwake. Mankhwalawa onse ndi ovomerezeka pakugwiritsidwa ntchito kwa nthawi yayitali, chifukwa chake ndikupitiliza kudzikongoletsa pa mankhwala opezeka pano.

Khalidwe la Orlistat

Mankhwalawa amapangidwa ndi KRKA (Slovenia) ndipo ali m'gulu la mankhwala omwe mfundo zake zimayendera chifukwa cha kuletsa kwa lipases ya m'mimba. Orlistat imapezeka m'mapiritsi omwe amakhala ndi zopunthira. Gawo la dzina lomweli likuwonetsa ntchito (mlingo wa 120 mg mu 1 kapisozi). Zomwe zimapangidwira zimaphatikizapo zinthu zopanda ntchito:

• cellcrystalline mapadi,
• sodium carboxymethyl wowuma,
• sodium lauryl sulfate,
• povidone
• talcum ufa.

Kufunikira kwa chithandizo chamankhwala cha Orlistat chimaperekedwa ndikusokoneza ntchito ya michere ya m'mimba.

Orlistat ikuwoneka motsutsana ndi mitundu yofananira chifukwa chogwira ntchito kwambiri pamilomo ya lipases (pancreatic, gastric). Izi zimapanga mgwirizano wolumikizana ndi ma serines awo. Chifukwa cha izi, njira yosinthira kwa triglycerides kuchokera m'mafuta omwe amalowa m'thupi ndi zakudya muzinthu zomwe zimatengedwa ndi makoma a mgonero: monoglycerides, mafuta acids ndi oletsedwa. Kufunikira kwa chithandizo chamankhwala cha Orlistat chimaperekedwa ndikusokoneza ntchito ya michere ya m'mimba.

Chifukwa cha njira zomwe zafotokozedwazi, mafuta amasinthidwa kukhala zinthu zomwe sizimayamwa ndi makoma amkati mwagaye ndipo amachotsedwedwa pakuyenda matumbo, njirayi imatenga masiku osapitilira 5.

Zotsatira zabwino za mankhwala zimaperekedwa chifukwa cha kuchepa kwa kalori chifukwa cha kuphwanya mafuta kagayidwe. Izi zimapangitsa kuti muchepetse kunenepa.

Mankhwalawa amaletsa kusintha kwa mafuta kupita ku mafuta acids ndi monoglycerides osati kwathunthu, koma ndi 30% yokha. Chifukwa cha izi, thupi limalandira chakudya chokwanira chofunikira kuti mukhale ndi thanzi, koma limataya mtima wofuna kudziunjikira mafuta ochulukirapo.

Maphunziro ambiri a zotsatira za Orlistat pakugwira ntchito kwa ziwalo zamkati ndi machitidwe, zotsatira zoyipa pakukula kwa kuchuluka kwamatumbo am'mimba komanso kugwira ntchito kwa ndulu sikunapezeke. Kapangidwe ka bile, komanso kuchuluka kwa kayendedwe ka matumbo, sikusintha. Mlingo wa acidity wa m'mimba ya m'mimba umagwiranso ntchito ndi choyambirira. Pa kafukufukuyu, maphunziro ena adawonetsa kuchepa kwapang'ono pazinthu zingapo zothandiza: calcium, magnesium, zinki, chitsulo, mkuwa, phosphorous.

Odwala onenepa kwambiri komanso ma pathologies ena angapo, kuwongolera kwathunthu kumadziwika. Ichi ndi chifukwa cha kuchepa kwa thupi, kusintha kwa zochita za michere. Pambuyo pa kutha kwa chithandizo chamankhwala ndi Orlistat, pali chiopsezo chobwezeretsa kulemera koyambirira. Komabe, kafukufuku wasonyeza kuti odwala ena okha ndi omwe amabwerera pang'onopang'ono magawo awo am'mbuyomu. Mankhwala tikulimbikitsidwa kwa nthawi yayitali. Nthawi yayitali ya maphunzirowa imachokera pa miyezi 6 mpaka 12.

Chizindikiro pakugwiritsa ntchito Orlistat ndikofunikira kwa kuchepa thupi (mwachitsanzo, kunenepa kwambiri). Chotsatira chabwino ndi kuchepa kwa minofu ya adipose pamitundu isanu ya 5-10% ya thupi lonse. Kuphatikiza apo, mankhwalawa amathandizidwa kuti achepetse kuwopsa kwa kulemera kwenikweni, ngati wodwalayo ali ndi vuto loti achepetse thupi. Zoyipa:

• zaka za ana (osakwana zaka 12),
• malabsorption syndrome,
• cholestasis
• hyperoxaluria
• nephrolithiasis,
• nthawi ya pakati, yoyamwitsa,
• kusalolera kwa thupi la zigawo za Orlistat.

Pa mankhwala, kunenepa kwambiri kumatha kuchepa, koma nthawi yomweyo, mavuto amawonekera:

• ndowe zimakhala mafuta,
• kulimbikitsa kunyoza kumachuluka, zomwe zimachitika chifukwa cha kuchulukitsidwa kwa zinthu kuchokera mthupi zomwe sizinasinthidwe ndipo sizimatengeka ndi makhoma am matumbo chifukwa chakutseka kwa kagayidwe kazakudya zamafuta.
• kapangidwe ka gasi kumachuluka,
• fecal incinuence nthawi zina zimadziwika.

Kumayambiriro kwa mankhwala a Orlistat, kumverera kwa nkhawa kumatha kuwoneka.

Nthawi zambiri, poyambira maphunziro, mankhwalawa amatuluka omwe amayamba chifukwa cha vuto lalikulu lamanjenje: kupweteka mutu, chizungulire, nkhawa, kusokonezeka kwa tulo. Izi zimachitikanso chifukwa chakuwonjezeka kwa moto wamafuta ndi kuwonjezeka kwa chiwopsezo cha thupi.

Makhalidwe a Xenical

Wopanga mankhwalawa ndi Hoffmann la Roche (Switzerland). Chida ichi chimawerengedwa ngati chiwongolero chachindunji cha Orlistat, chifukwa cha kapangidwe kake (gawo lomwe limagwira ndi orlistat pamsasa wa 120 mg). Kuchita kwa Xenical, monga Orlisat, kumakhazikitsidwa ndi kuletsa kwa lipases ya m'mimba. Xenical imaperekedwa mu fomu 1 yotulutsira - mwa mawonekedwe a makapisozi.

Gawo lochita ntchito sililowa m'magazi, limatulutsidwa mosasunthika m'thupi (83% ya mlingo wonse).

Kuwongolera mkhalidwe wa wodwalayo kumadziwika m'masiku oyambira atangoyamba kumene maphunziro. Mankhwalawa amachotseredwa pakatha masiku atatu. Gawo lolimbikira limapukusidwa m'makoma a matumbo, ndikutulutsidwa kwa mankhwala 2. Poyerekeza ndi orlistat, ma metabolites awa amawonetsa ntchito zochepa, zomwe zikutanthauza kuti zimakhudza lipases ya m'mimba pang'ono.

Zisonyezero zogwiritsidwa ntchito:

• kunenepa kwambiri kapena kunenepa kwambiri pamaso pa zinthu zomwe zimapangitsa kuti munthu azichita kunenepa kwambiri,
• Chithandizo cha odwala omwe ali ndi mtundu wachiwiri wa matenda a shuga omwe amakonda kulemera (BMI kuchokera ku 27 kg / m more kapena kupitilira apo).