Mapiritsi apamwamba a noliprel

Ndimamwa zaka 2 za Noliprel. Pakadali pano, Mlingo wa 2,5 mg ndi wokwanira kuthana ndi mavuto. Nthawi zina umadzuka pomwe nyengo yasintha. Zotsatira zoyipa za netiweki. Pakamwa panga pamakhala kowuma ndipo nthawi zina ndimatsukidwa, koma izi ndimapangidwe ofanana ndi mutu wosalekeza komanso kusokonekera bwino.

Imasinthasintha magazi.

Dotolo adati, mwina, muyenera kumwa mapiritsi moyo wanu wonse.

Amayi adadwala matenda a sitiroko ndipo adotolo adati awunikire kwambiri mayesedwe awo. Kudumpha kulikonse kumatha kubweretsa zotsatira zoyipa kwambiri. Timatenga Noliprel 5 mg kamodzi patsiku ndipo mpaka pano palibe mavuto omwe abwera chifukwa cha kuthamanga kwa magazi. Njira yabwino yothetsera.

Ndidayesa kuchepetsa kupanikizika kuphatikiza concor. Zotsatira zake zimakhala zabwino, koma chifuwa chowuma komanso chizungulire chochepa chidawonekera. Mwinanso muyenera kutengera fanizo.

Amachepetsa kuthamanga kwa magazi mwachangu.

Zotsatira zoyipa zidawonekera.

Ndakhala ndikutenga Noliprel kwa chaka pafupifupi tsiku lililonse. Poyamba ndinkaopa kuti pakhoza kukhala zovuta, koma pakadali pano zonse sizachilendo. Koma kuthamanga kwa magazi ndizabwinobwino. Ndidasankha mapiritsiwa chifukwa chololedwa mtundu wa shuga.

mapiritsi amathandizira kuti kupanikizika kukhale pansi

Sindinapeze panobe

Ndimamwa zaka 2 za Noliprel. Pakadali pano, Mlingo wa 2,5 mg ndi wokwanira kuthana ndi mavuto. Nthawi zina umadzuka pomwe nyengo yasintha. Zotsatira zoyipa za netiweki. Pakamwa panga pamakhala kowuma ndipo nthawi zina ndimatsukidwa, koma izi ndimapangidwe ofanana ndi mutu wosalekeza komanso kusokonekera bwino.

Imasinthasintha magazi.

Dotolo adati, mwina, muyenera kumwa mapiritsi moyo wanu wonse.

Amayi adadwala matenda a sitiroko ndipo adotolo adati awunikire kwambiri mayesedwe awo. Kudumpha kulikonse kumatha kubweretsa zotsatira zoyipa kwambiri. Timatenga Noliprel 5 mg kamodzi patsiku ndipo mpaka pano palibe mavuto omwe abwera chifukwa cha kuthamanga kwa magazi. Njira yabwino yothetsera.

Ndidayesa kuchepetsa kupanikizika kuphatikiza concor. Zotsatira zake zimakhala zabwino, koma chifuwa chowuma komanso chizungulire chochepa chidawonekera. Mwinanso muyenera kutengera fanizo.

Amachepetsa kuthamanga kwa magazi mwachangu.

Zotsatira zoyipa zidawonekera.

Ndakhala ndikutenga Noliprel kwa chaka pafupifupi tsiku lililonse. Poyamba ndinkaopa kuti pakhoza kukhala zovuta, koma pakadali pano zonse sizachilendo. Koma kuthamanga kwa magazi ndizabwinobwino. Ndidasankha mapiritsiwa chifukwa chololedwa mtundu wa shuga.

mapiritsi amathandizira kuti kupanikizika kukhale pansi

Sindinapeze panobe

• Timalola ndemanga kapena zonyoza kapena zonyoza.
• Tiuzeni za luso lanu pakugwiritsa ntchito kapena kugwira ntchito.
• Ngati muwunikenso za malo ogulitsa kapena ntchito, onetsani nambala yolamula. Mwina izi zithandiza oimira makampani kuthetsa vutoli.
• Sonyezani zabwino ndi zoyipa
• Voterani
• Mabungwe - tsamba limakhala ndi ndemanga za ogwira ntchito pakampani ndi kuwunikira kwa makasitomala (ogula)

Momwe mungagonjetse matenda oopsa? Mwinanso, sanapeze yankho lenileni la funsoli. Ndidatenga mankhwala kwakanthawi mpaka ndidapeza mankhwala otchedwa Noliprel. Chida ichi chili ndi mphamvu, choncho sichoyenera aliyense. Ndinagula mapiritsi a mankhwala. Mwambiri, ndinali wokhutira ndi zotsatira za chithandizo, ndiyesetsa kugawana ndi inu momwe ndikumvera.

Zizindikiro zogwiritsidwa ntchito

Noliprel amadziwika kuti ndi imodzi mwazamankhwala abwino kwambiri othandizira matenda oopsa. Kwa iwo omwe sakudziwa, ndi nthawi iyi, madokotala amamvetsetsa matenda omwe amadziwika ndi kuwonjezeka kwa kuthamanga kwa magazi. Chosasangalatsa kwambiri ndikuti kudzivulaza kumachitika pang'onopang'ono ndipo munthu alibe nthawi yoyankhira akudwala. Zinachitikanso kwa ine.

Ndinazindikira zoyamba za matenda a kanthawi pang'ono zapitazo. Makutu anga nthawi zambiri anali phokoso, mutu wanga umapweteka, ndipo ntchentche zimawonekera m'maso mwanga. Ndimaganiza kuti amawonetsa kutopa kwa banal. Ndimagwira ntchito "yophera", choncho sindinathe kupeza nthawi yopuma mwabwinobwino.

Adaganiza zopita kwa adotolo atangozindikira atayamba kunena kuti nkhope yake imakhala yofiyira. Ku chipatala, ochiritsirawa adanditsogolera kwa dokotala wamtima.

"Ngakhale muli aang'ono, muli ndi ziwonetsero zonse zofunika pa matenda oopsa. Ndikofunikira kuthetsa vutoli tsopano, apo ayi mufika pamavuto. Ndikupangira kuyamba ndi ACE inhibitors, diuretics ndi potaziyamu antagonists. Mndandanda wamankhwala ngati awa ndiwambiri ... "

Grigory Sergeevich, cardiologist, arrhythmologist, Moscow

Nditatha kulankhula ndi adotolo, ndidayamba kusankha mankhwala omwe amachepetsa zizindikiro zanga. Ndipo, pomaliza, adasankha mapiritsi a Noliprel. Tsopano ndiyesetsa kufotokoza chifukwa chake.

Ndemanga Zamakasitomala a Noliprel

Nditabwerako kuchokera ku chipatala, ndidayamba kufunsa zamankhwala zosokoneza bongo pa intaneti. Kusankhidwa kwa mapiritsi, jakisoni ndi ufa kunalidi kwakukulu. Dotolo adalangiza mayina angapo, koma kuweruza ndi kuwunika kwa odwala kunali zosankha komanso zosangalatsa. Cardiologist adalemba njira zotsika mtengo kwambiri, koma sindikufuna kupulumutsa, koma kwenikweni sinthani vutolo (kapena siyang'anireni).

Kuwerenga malingaliro osiyanasiyana pamankhwala, ndidapeza matchulidwe a mapiritsi a Noliprel. Anthu ena analemba kuti mankhwalawa amachepetsa kuthamanga kwa magazi msanga. Komanso, chida china nthawi zina chimakhala champhamvu kwambiri. Izi ndizomwe zimandisangalatsa - zikutanthauza kuti zimathandizadi! Adakwera pa netiweki kukafunafuna malingaliro pa zinthu zinazake.

“Matenda olembetsa magazi ndi chilango chachikulu. Zinali zovuta kwambiri kugwa. Kupsinjika kulikonse, mwathupi komanso m'maganizo, kudapangitsa kupweteka mutu kwambiri komanso nseru. Ndinkada nkhawa kuti ndikulumpha ndikakumana ndi vuto la mtima kapena sitiroko. Ndinayamba kutenga Noliprel pa upangiri waogwira naye. Mapiritsi abwino. Ndimamwa pasadakhale ndipo sindikuvutika ndi nyengo ... "

Nthawi zambiri pamakhala ndemanga za anthu omwe adayamba kumwa Noliprel atatha kuyesa gulu la mayendedwe ake. Monga ndimamvetsetsa, mapiritsi awa ndi amphamvu kwambiri, motero mtengo wake ndi wokwera.

“Sindinathe kupirira kutupa kumaso ndi miyendo. Madotolo adati chifukwa cha kuthamanga kwa magazi komwe impso zimagwira bwino ntchito ndipo madzimadzi amadziunjikira mthupi. Ndinayesa mankhwala osiyanasiyana osiyanasiyana, koma zotsatira zake sizinali zabwino. Ndidamva mwangozi kukambirana pakati paopenshoni awiri za Noliprel. Ndinaganiza zogula kuti ndikayezetse ndipo ndazindikira kuti tsopano ndapeza zomwe ndikufuna ... "

Panali, zowunikira zoyipa. Amakhudzana ndi zovuta za mankhwalawo. Nthawi zambiri, anthu ankadandaula kuti pambuyo pa maphunziro a Noliprel adagona zosokoneza komanso pakamwa pouma. Izi sizinandiwopsyeze, kotero ndidaganiza kuti ndisamvere.

Malangizo apadera ndi fanizo la mankhwalawa

Zinali zofunika kwambiri kwa ine kuti mapiritsi sanakhudze momwe amvera. Ndiyenera kuyendetsa kwambiri, kotero ndidayang'ana mwachindunji. Sindinapeze zotsatira zoyipa zomwe zimakhudzana ndikuyendetsa galimoto. Ndilemba mawu ochepa okhudza kusintha kwa Noliprel ndi analogues. Ndidakumana ndi anthu omwe amafuna njira ina yothanirana ndi mankhwala (nthawi zambiri chifukwa cha ziwengo). Mndandandawu siwotalika kwambiri. Omwe amatchulidwa kwambiri anali Perindid ndi Ko-Perineva.

Pamapeto pa kuwunika kwanga, ndilemba zakukhosi kwanga. Poyamba, Noliprel sanazindikire kanthu mwapadera, ngakhale kukhumudwa pang'ono. Komabe, sindinasiye chithandizo, popeza kusintha kwam'tsogolo kunayamba kuonekera patatha pafupifupi milungu iwiri. Adanenanso za kuchepa kwa mashopu kuyambira masokosi pamiyendo yake madzulo (zomwe zikutanthauza kuti kutupa kumatha) komanso kuwongolera bwino. Mutu wanga unasiya kutulutsa ndipo mseru unadutsa. Adotolo adati mwina ndiye kuti muyenera kugula mtengo waukulu, koma pakadali pano zonse zili bwino.

Achire zotsatira za Noliprel

Noliprel ndi mankhwala ophatikiza matenda oopsa, omwe amaphatikizapo perindopril ndi indapamide. Zinthu zonse ziwiri zomwe zimagwira ntchito zimatsitsa kuthamanga kwa magazi komanso kutsika, ndikugwirizana molimbikitsana.

Ubwino wa mapiritsi a Noliprel pochizira matenda oopsa:

• Kuchita bwino kwa kuphatikiza kwa perindopril ndi indapamide kumatsimikiziridwa machitidwe.
• Mankhwalawa alibe zotsatira zoyipa zama kagayidwe, siziwononga machitidwe oyeserera magazi a cholesterol, triglycerides ndi glucose, oyenera matenda a shuga.
• Indapamide imadziwika kuti ndi imodzi mwazitetezo zotetezeka kwambiri ndipo imagwira ntchito nthawi imodzi.
• Zochita piritsi lililonse la Noliprel zimatha maola 24, motero ndikokwanira kumwa mankhwalawa kamodzi patsiku.
• Pambuyo pakulekana ndi chithandizo, matendawo amayamba, mwachitsanzo, kupanikizika sikumachita zambiri.
• Mankhwala mwamphamvu amachepetsa kupanikizika kwa systolic ndi diastolic, kuyimirira ndikugona.
• Mlingo wa hypertrophy wa ventricle wamanzere wamtima umachepa, i.e., chiwopsezo cha matenda amtima chimachepa. Izi zimayimira palokha pakuchepetsa kuthamanga kwa magazi.

Noliprel amatsutsana ndi pakati komanso poyamwitsa. Ndikosayenera kumwa mankhwalawa mu 2nd ndi 3 trimesters ya mimba, koma koyambirira sikofunikira.

Ndikulimbikitsidwa kuleka kuchiza matenda oopsa ndi mapiritsi a "mankhwala" milungu ingapo milungu isanachitike. Ngati kutenga pakati kumachitika pakumwa mapiritsi osakanikirana, ndiye kuti palibe chifukwa chododometsa, koma mayi ayenera kusiya kumwa mankhwala oopsa, kuyezetsa mwana wosabadwayo ndikuwonana ndi dotolo momwe angachitire matenda oopsa kwambiri.

Noliprel sioyenera kuchitira matenda oopsa ngati wodwala anali ndi mawonekedwe a hypersensitivity kwa ACE zoletsa, makamaka, perindopril. Chowopsa kwambiri pazowonetsa izi ndi edema ya Quincke. Ngati chifuwa chowuma sichingalekere, ndiye kuti mankhwalawo amayenera kuti aletsedwe. Adotolo adzaisintha ndi mankhwala othandizira matenda oopsa kuchokera ku kalasi ina.

Mankhwalawa sanatchulidwe kapena kugwiritsidwa ntchito mosamala kwambiri pakakhala vuto lalikulu la impso:

• bilteryal aimpso mtsempha wamagazi,
• mitsempha ya minyewa ya impso yokhayo,
• kuchuluka kwa kusefedwa kwa 30 ml / mphindi ndi pansipa.

Mosamala kwambiri, Noliprel ayenera kulembedwa motere:

• kulephera kwamtima kwambiri, komwe kumatsatana kapena sikumayendera limodzi ndi kulephera kwa impso,
• matenda a chiwindi, omwe amakhala ndi edema ndi ascites,
• wodwala wayamba kusanza komanso / kapena kutsegula m'mimba.

Munthawi zonsezi, kugwiritsa ntchito mankhwalawa kungayambitse kuchepa kwambiri kwa magazi, makamaka pambuyo piritsi loyambirira, komanso pakatha milungu iwiri yoyambirira ya mankhwala. Palinso chiwopsezo cha kuchepa kwambiri kwa kuthamanga kwa magazi kwa odwala omwe amatsatira zakudya zopanda mchere.

Mukamamwa Noliprel, muyenera kuwunika nthawi zonse ngati pali zizindikiro za kuchepa mphamvu kwa magazi ndi kuchepa kwa madzi m'magazi a m'magazi. Nthawi yomweyo, kutsika kwamphamvu kwa kuthamanga kwa magazi chifukwa cha mlingo woyamba sikukulepheretsani kugwiritsa ntchito mankhwalawa. Dokotala atha kupangira kutsitsa mlingo kapena kusinthira ku indapamide kapena perindopril payokha, popanda gawo lachiwiri la mapiritsi ophatikizidwa. Kwa odwala okalamba, ndikulimbikitsidwa kwambiri kuti kuyesedwa kwa magazi kumayenera kutengedwa musanayambe Noliprel kuti muwone ntchito zokhudzana ndi impso komanso kuchuluka kwa potaziyamu mu plasma.

Palibenso kupuma pang'ono, kupweteka mutu, kupsinjika ndi zizindikilo zina za HYPERTENSION! Owerenga athu akugwiritsa ntchito kale njirayi kuthana ndi kukakamizidwa.

Wodwala yemwe adalembedwa Noliprel kapena zoletsa zina za ACE pakuwonetsa matenda oopsa ayenera kuyang'anitsitsa ndende ya creatinine m'madzi a m'magazi. Chifukwa kutsekereza renin-angiotensin-aldosterone dongosolo ndi perindopril kapena zoletsa zina za ACE zingayambitse kulephera kwa impso, nthawi zina pachimake. Vutoli limachitika kawirikawiri, komabe, tikulimbikitsidwa kuti muyambe kugwiritsa ntchito mankhwala osokoneza bongo mosamala, ndikukula mapiritsi pang'onopang'ono. Muyeneranso kuyang'anitsitsa kuchuluka kwa potaziyamu mumadzi am'magazi. Mulingo wake wovomerezeka ndi 3.4 mmol / l ndikukwera. Ngati potaziyamu wambiri m'magazi agwera pansi pazoyenera, ndiye kuti izi zikutanthauza chiopsezo chamtima, chomwe chitha kupha.

Kuyang'anira odwala mapiritsi ambiri a Noliprel kumatsimikizira kuti mankhwalawa amachepetsa kuthamanga kwa magazi. Nthawi zambiri zimathandizira kukhala ndi kupanikizika pansipa 140/90 kapenanso pansi pa 130/80 mmHg. Art. ndipo potero amachepetsa chiopsezo cha matenda amtima, kugwidwa, kulephera kwaimpso. Noliprel nthawi zambiri imathandizira ngakhale poti mankhwala ena alibe ntchito, ndipo izi zimapangitsa kuti mtengo wake ukhale wokwera mtengo.

Ndili ndi zaka 41, kutalika 168 masentimita, kulemera kwa makilogalamu 72, mpaka posachedwapa anali 79 kg. Ndakhala ndikutenga Noliprel A Forte kwa matenda oopsa kwa zaka zitatu. Posachedwa, ndimatha kuchepetsa thupi, koma pambuyo pake mankhwalawo adayamba kukulira. Munali zowawa pamtima, nthawi zina mutu umapindika. Kupanikizika kumagwa kwambiri. Ndimalingalira posinthana ndi Physiotens - mankhwala osachepera. Mwina nditenga mosiyana Indapamide kapena perindopril (Prestarium).

Mphamvu yamphamvu ya Noliprel imatsimikiziridwa osati kokha ndi odwala, komanso ndi madokotala pakuwunika kwawo kosasimbika, komanso maphunziro omwe zotsatira zake zimafalitsidwa m'magazini azachipatala. Mavuto omwe amakhalapo kwa odwala omwe ali ndi matenda oopsa okhudzana ndi kugwiritsa ntchito mankhwalawa amawonekera pamene odwala samatsata malangizo a dokotala komanso / kapena malangizo a mankhwalawo.

Ndili ndi Noliprel adalimbana kwambiri zaka 8. Pamwamba pa 130/90 iwo kwenikweni sanatuluke. Mutu wapafupipafupi wapita kuyambira sabata yatha. Ndinayetsa kupanikizika - 140 / 100-150 / 110, ndipo m'mawa kutacha. Pazifukwa zina, mankhwalawa anasiya kugwira ntchito. Thupi limagwiritsidwa ntchito kwa icho kapena mkhalidwe waumoyo umakulirakulira ndi ukalamba. Tsopano mukuganiza: kuwonjezera kuchuluka kwa Noliprel kapena kusinthira ku mankhwala ena? Ndili ndi zaka 47, onenepa kwambiri. Ntchito yaofesi, oyang'anira, amanjenje.

Noliprel, monga mapiritsi ena oopsa, amayenera kumwa pafupipafupi, tsiku lililonse, osati m'maphunziro kapena mukakhala kuti akukupanikizani.

Ndakhala ndikutenga Noliprel A kwa matenda oopsa kwa zaka zingapo m'mawa. Miyezi ingapo yapitayo, mnzake (osati dokotala) adalangiza Cardiomagnyl kuti awonjezeredwe kwa iwo asanagone. Ndili wokondwa kwambiri ndi zotsatira zake. Kupanikizika sikunachepe, chifukwa Noliprel adagwira bwino. Koma zikuwoneka kuti magnesium ndi aspirin zimapangitsa mitsempha yamagazi, kuyendetsa magazi kudzera mwa iwo, chifukwa chake, thanzi limayenda bwino. Mwina dongosolo la Noliprel + Cardiomagnyl likuthandizirabe munthu wina.

Mapiritsi a Cardiomagnyl ali ndi milingo yotsika kwambiri ya magnesium, kotero palibe nzeru kuchokera kwa iwo. Alinso ndi aspirin, omwe angayambitse magazi m'mimba. Kugwiritsa ntchito kwa aspirin kuti muchepetse vuto la kugunda kwa mtima sikunatsimikizidwe, ndipo kuopsa kwa magazi kumatsimikiziridwa motsimikiza ndi machitidwe. Tengani magnesium ndi vitamini B6 pamapiritsi a Magne-B6, Magnerot, Magnicum, Magvit. Werengani nkhani "Magnesium - michere yayikulu mukudya kwamankhwala oopsa" mwatsatanetsatane.

Anthu nthawi zambiri amadandaula za zotsatira zoyipa chifukwa chakuti mankhwalawa amachepetsa kuthamanga kwa magazi kwambiri. Zikatero, kufooka, kufoka, kutopa, kusowa chidwi pantchito kumatha kumveka. Chifukwa chake, muyenera kusinthira pamapiritsi ndi mlingo wochepetsera wa zinthu zonse zogwira ntchito, zomwe ndi gawo la mankhwala ophatikizika. Kapena, ngati matenda olembetsa magazi ali ofatsa, ndiye kuti Noliprel ndi wamphamvu kwambiri piritsi, ndipo muyenera m'malo mwake ndi ofewa. Osachita izi popanda chilolezo, koma dokotala.

Noliprel - mapiritsi amphamvu opsinjika, koma osati panacea. Ndakhala ndikumwa mankhwalawa m'mawa uliwonse kwa nthawi yayitali - 2 mg ya perindopril ndi 0,625 mg ya indapamide piritsi limodzi. Kwa zaka zingapo zonse zinali bwino, koma tsopano mavuto ayamba kukwera. Ndidapita kwa adotolo - adati ndikawonjezere wina Nebile.Kutsatira malangizowo - adathandizidwadi. Koma ndikumvetsetsa kuti uku ndi kwakanthawi. Ndinaganiza zokhala moyo wabwino kuti ndikane mankhwala osokoneza bongo. Chifukwa chake ndafika patsamba lanu. Ngakhale mapiritsi okwera mtengo sangathe kuchepetsa kupsinjika. Yakwana nthawi yoti muchite thanzi lanu.

Odwala pakuwunikira kwawo nthawi zambiri amadandaula zazotsatira zoyipa zamankhwala osakanikirana amphamvu kuphatikiza, kuphatikizapo Noliprel. Nthawi zambiri zoyipa izi zimakhala zosasangalatsa, koma osati zolimba kwambiri kotero kuti muyenera kusiya kumwa mapiritsi. Komanso, atha kusinthidwa ndikusintha kukhala ndi moyo wathanzi.

Chifukwa cha kufalikira kwa kuthamanga kwa magazi pomwe mukumwa mankhwalawo, kupweteka mutu kumachoka, chikumbumtima chitha. Kuchokera pamenepa, thanzi limayenda bwino kuposa zopsinjika chifukwa cha zovuta. Nthawi zambiri chifuwa chowuma chimayamba, koma nthawi zambiri chimakhala chizindikiro. Ndiye kuti, ngati odwala sakudziwa kuti perindopril, monga zoletsa zina za ACE, zimayambitsa chifuwa, ndiye kuti sangakhale ndi zotsatirapo zake.

Kafukufuku wambiri wachitika womwe watsimikizira kufunika ndi chitetezo chokwanira cha perindopril komanso indapamide chokha pochiza matenda oopsa. Pambuyo pake, mankhwalawa ochepetsa magazi amaphatikizidwa kuti apange mankhwala osakanikirana amphamvu a Noliprel. Mu 2000s, idayesedwa mosamala mu labotale, kenako kwa odwala enieni, kuti muwone kuyendetsa bwino komanso kuchuluka kwa zoyipa.

Kusanthula kwa mapiritsi a kukakamiza Noliprel

Zotsatira za maphunzirowa zidatsimikizira akatswiri kuti Noliprel siothandiza kokha, komanso otetezeka. Chifukwa chake, nthawi zambiri limalembedwa kwa odwala. Tikhazikike padera pa mutu wa chithandizo cha matenda oopsa pakati pa odwala omwe ali ndi mtundu wa matenda a shuga 2 ogwiritsa ntchito mapiritsi awa

Mu 2012, zotsatira za kafukufuku wa Chiyukireniya PRACTICE zidafalitsidwa. Idawerengera bwino komanso chitetezo cha kulemba mapiritsi a Noliprel motsutsana ndi kukakamiza kwa omwe matendawa amaphatikizidwa ndi matenda a shuga. Ophunzirawo anali amuna ndi akazi okwanira 762 azaka zopitilira 40, pomwe matenda oopsa am'mimba adapangidwa ndi matenda ashuga amtundu wa 2. Odwala awa anali ndi kuwerenga kwa magazi kwa 160/100 mmHg. mpaka 200/120 mmHg M'mbuyomu, onse sanamwe mapiritsi kuti akakamizidwe kapena kumwa, koma mankhwalawo sakanatha kuchepetsa kupanikizika kwawo kosakwana 140/90 mm Hg. Art.

Kwa odwala onsewa, madokotala adalemba Noliprel Bi-Fort, piritsi limodzi patsiku. Mankhwala onse omwe anthu odwala matenda ashuga adatenga kale adatha. Patatha mwezi umodzi ndikuchita Noliprel Be-forte, kuwongolera koyamba kwa zotsatira kunachitika. Ngati kuchuluka kwa kuthamanga kwa magazi kukadapitilira 140/90 mm Hg, ndiye kuti amlodipine 5 mg amawonjezeredwa kamodzi patsiku. Pambuyo pake, ngati pakufunika, mlingo wa amlodipine unakulitsidwa mpaka 10 mg patsiku.

Njira zochizira matenda oopsa "Katatu"

1. Wodwalayo amapatsidwa mapiritsi a Noliprel Bi-Forte kamodzi patsiku. Perindopril 10 mg + indapamide 2.5 mg ndikuwombera kawiri.
2. Ngati patatha mwezi umodzi kupanikizika kumakhalabe pamwamba pa 140/90 mm Hg. Art., Onjezerani amlodipine 5 mg 1 nthawi patsiku.
3. Pambuyo pa masabata 2-4, mlingo wa amlodipine ukhoza kuchulukitsidwa mpaka 10 mg pa tsiku, ngati kukakamiza sikumatsikira mpaka komwe mukufuna.

Kutsika kwapakati pa kupsinjika kwapamwamba (systolic) mwa ophunzirawo kunali 44.7 mm Hg. Art., Ndi kutsika (diastolic) kukakamiza - 21.2 mm RT. Art. Pambuyo pa miyezi itatu, 62.4% ya odwala omwe ali ndi matenda oopsa komanso matenda a shuga adakwanitsa kufikira zomwe akufuna

Zambiri, INN

Mankhwala Noliprel ali m'gulu la antihypertensive mankhwala. Mapiritsi opanikizika amaphatikizidwa, amaphatikiza zigawo ziwiri. Izi, zimathandizanso kuthandizira kwamankhwala.

International Non-Proprietary Name (INN) imatchula dzina lapadera la chinthu chogwiritsidwa ntchito ndi WHO. INN Noliprela - Perindopril ndi okodzetsa.

Maonekedwe ndi mtengo wapakati

Mankhwalawa amapangidwa ngati mapiritsi oyera oblong. Pali mitundu itatu ya mankhwala omwe amasiyana mu kuchuluka kwa perindopril (P) ndi indapamide (I):

• Noliprel A Forte: P - 5 mg, I -1.25 mg,
• Noliprel Bi: P - 10 mg, I - 2.5 mg,
• Noliprel Arginine: P - 2,5 mg, I - 0,625 mg.

Fomu yotulutsa katundu

Mtengo wa mankhwala zimatengera mtundu wa mankhwala, mlingo, malo ogulitsa:

• ku St. Petersburg, mtengo umachokera ku 630 mpaka 850 rubles,
• ku Moscow, mapiritsi amatengera 555 mpaka 818 rubles.

Kapangidwe ndi kapangidwe ka zochita

Mankhwalawa ali ndi zigawo ziwiri zikuluzikulu: perindopril ndi indapamide. Piritsi ili ndi synergistic ya zinthu ziwiri za antihypertensive:

Perindopril, wokhala choletsa enzyme yotembenuza angotensin, amaletsa vasoconstrictor zotsatira za michere. Kutseka kwa ACE kumabweretsa kuchepa kwa kupanga kwa aldosterone, ndipo m'magazi am'magazi, ntchito ya renin imakulanso.

Kuthamanga kwa magazi kumachepa mu odwala omwe ali ndi vuto wamba komanso lotsika plasma renin. Komanso, gawo la piritsi kudzera mu vasodilator momwe limakhazikitsira mitsempha limachepetsa kutsitsa pamtima, ndipo chifukwa chakuchepa kwa kamvekedwe ka ziwiya zotumphukira, kumachepetsa kutsitsa. Kuchulukitsa kwa myocardial kulolera pamavuto.

Mankhwalawa ali ndi vuto lochititsa chidwi, kutsitsa kuthamanga kwa magazi kwa odwala azaka zilizonse, mosasamala kanthu za thupi. Mutatha kumwa mankhwalawa, antihypertensive zotsatira zimatha maola 24. Kuchepa kwa kuthamanga kwa magazi kumachitika kwakanthawi mwezi umodzi popanda kupangika kwa tachyphylaxis (kuchepa kwa mphamvu ya ma pharmacological a mankhwala).

Zotsatira zabwino za mankhwalawa zimapangidwa chifukwa cha kugwirizanitsidwa kwa zomwe zigawo zake zimapanga.

Zizindikiro ndi contraindication

Muyenera kudziwa momwe kugwiritsa ntchito antihypertensive mankhwala, makamaka, Noliprel, kuli koyenera. Chizindikiro chachikulu ndikuwuka kwa kupanikizika kwa systolic pamtunda wa 140, diastolic - zoposa 90.

Mikhalidwe yomwe mapiritsi sakulimbikitsidwa:

• tsankho la mankhwala, zida zake,
• kulephera kwa aimpso
• kukanika kwa hepatic,
• hepatic encephalopathy,
• nthawi ya chiwindi B ndi pakati,
• ana ndi achinyamata.

Osanyalanyaza zotsutsana pamwambapa. Izi sizingobweretsa zofunikira zochizira, koma zimabweretsa zovuta ndi zovuta zina.

Momwe mungawerengere mlingo?

Malangizo ogwiritsira ntchito amafotokozera malamulo ogwiritsira ntchito mapiritsi kuti akwaniritse kwambiri achire. Mankhwalawa amamwa pakamwa. Choyamba, piritsi limodzi limayikidwa, pakakhala kuti sizingatheke, ndizotheka kuwonjezera kuchuluka kwa awiri.

Simungasinthe mlingo nokha, chifukwa izi zili ndi zotsatirapo zoipa. Ngati timayankhula za kumwa mankhwalawa, musanadye kapena mutatha kudya, ndibwino kumwa mapiritsi m'mawa, pamimba yopanda kanthu, ndi kapu yamadzi ofunda.

Anthu omwe ali ndi vuto la impso, kumwa mankhwalawo akuwonetsedwa motsogozedwa ndi creatinine chilolezo.

Zotsatira zoyipa ndi bongo

Popeza mankhwalawa ndi mankhwala, kugwiritsa ntchito kwake kumatha kuyambitsa zovuta kuchokera ku ziwalo ndi machitidwe osiyanasiyana. Zotsatira zoyipa zalembedwa:

• mbali ya magazi ndi zamitsempha yamagazi dongosolo - eosinophilia, agranulocytosis, aplastic anemia, leukopenia, thrombocytopenia,
• chitetezo cha mthupi chimayankha mwachangu hypersensitivity reaction. Nthawi zambiri, pakhungu pamakhala zotupa,
• ndi kuwonongeka kwa mitsempha, pali kuphwanya kwamva, kupweteka mutu, kufooka, kugona.
• masomphenya osalala
• tinnitus
• kuchepa kwakukulu kwa kupanikizika, orthostatic hypotension (ndi kuwuka mwachangu pamalo abodza), kuphwanya malumbo a mtima,
• chifuwa chowuma chomwe chazimiririka pakasiya mankhwala,
• kusokoneza kukoma kwa kuzindikira, nseru, kupweteka kwam'mimba, kudzimbidwa.

Kuti muchepetse chiopsezo chosafunikira, musanakulembeni mankhwala, muyenera kukayezetsa ndi kulandira mayeso oyambira.

Kuchita ndi Mowa ndi Mankhwala Ena

Chisamaliro chiyenera kutengedwa kuphatikiza mankhwalawa ndi mankhwala ena. Ngati mumamwa mankhwala ndi kukonzekera kwa lithiamu nthawi yomweyo. Izi zichititsa kuti kuchuluka kwa lithiamu m'magazi kukwere, ndikuwonjezereka kwake.

Kugwiritsa ntchito palimodzi ndi mankhwala osagwiritsa ntchito mankhwala a anti-yotupa kumabweretsa kuwonongeka kwa ntchito yowonongeka, muzovuta kwambiri - kukulitsa kulephera kwa impso.

Mankhwala omwe amapezeka mwa anthu okalamba amafunikira chisamaliro chowonjezereka, chifukwa ali ndi ma pathologies ambiri ogwirizana.

Ma antidepressants ndi ma antipsychotic amalimbikitsa hypotensive zotsatira ndikukulitsa chiopsezo cha kugwa kwa orthostatic.

Kugwiritsa ntchito munthawi yomweyo renin inhibitors (Aliskiren) kumapangitsa kuti potaziyamu azikhala mokwanira mu mkodzo, kuwonongeka kwa mtima ndi impso, komanso kufa.

Kugwiritsa ntchito mankhwala othandizira odwala matenda ashuga kumathandizira kuchepa kwambiri kwa shuga m'magazi ndikupanga chipere cha hypoglycemic.

Kutenga diuretics kumabweretsa kuchepa kwamphamvu komanso kuthamanga kwa kukakamiza, kuchulukitsidwa kwa excretion wa potaziyamu kuchokera m'thupi.

Kuphatikiza kwa antihypertensive ndi mowa kumapangitsa kuti pakhale vuto lalikulu kwambiri, aneurysm, vuto la mtima, kotero kuphatikiza uku ndikosayenera.

Ma Analogs ndi mankhwala omwe ali ndi zosakaniza zofanana ndi mankhwala oyambirirawo, komanso INN yofanana. Mankhwala odziwika kwambiri:

Ngati mukulephera kumwa kapena mankhwalawa, mutha kusintha m'malo mwake ndi yofanana. Mutha kusankha mankhwala omwe amagwira ntchito moyenera momwe angathere ndipo adzakhala otsika mtengo.

Ndemanga za madokotala ndi odwala

Pafupifupi 75% ya odwala omwe adawafunsidwa amalimbikitsa kumwa mankhwalawo. Kuyesedwa koyenera kumalumikizidwa ndi kulekerera bwino kwa mankhwalawo, zoyipa - ndi mtengo wokwera, koma pali malingaliro olakwika a odwala, ngakhale ali ochepa:

Ivan, wazaka 67: “Ndinakhuta ndi mapiritsi a Noliprel, chifukwa ndakhala ndikuwatenga kwa zaka pafupifupi zisanu. Munthawi imeneyi ndimamva bwino, koma ndazindikira kuti sabata yatha mavuto anali atakulirakulira, ngakhale ndikumwa mankhwalawo.

Ndidapita kwa dotolo wanga ndikalandira lingaliro - onjezani Nebilet (beta-blocker) ku mankhwala akulu. Zinthu zikuyenda bwino. Koma ndikumvetsa kuti izi ndizosakhalitsa. Ndikufuna kukana kumwa mankhwala ambiri, chifukwa chake ndiziwunika kudya komanso zolimbitsa thupi. Ndikukhulupirira kuti zonse zitha. ”

Maganizo a Cardiologist alinso abwino:

Alena, wazaka 35, dokotala wamtima: “Noliprel ndi mankhwala abwino a antihypertensive. Kuphatikizidwa kwa zigawo zake kumapereka mphamvu, zomwe zimaphatikizapo kuchepetsa systolic ndi diastolic, zomwe zimatha maola 24.

Mankhwalawa ali ndi mtima wogwira - amachepetsa kuuma kwa matenda am'mitsempha yama mtima, amapangitsa makoma amitsempha kukhala odikirira. Kuphatikiza apo, amachepetsa kukana kwamitsempha yonse ndipo sikukhudza kagayidwe ka mafuta. Mankhwalawa alibe mankhwala osokoneza bongo ndipo samakulitsa kugunda kwa mtima.

Mankhwala amagwira ntchito mankhwalawa ofunika matenda oopsa (chifukwa chomwe sichinadziwike). Mwa anthu omwe ali ndi matenda a shuga a 2, mankhwalawa amalepheretsa kukula kwa angiopathies - zovuta za mtima. Amamwa kamodzi m'mawa pamimba yopanda kanthu, komanso yothandiza kwambiri kwa odwala. ”

Kuchokera pazomwe tafotokozazi, titha kunena kuti Noliprel amatchedwa mankhwala osakanizika omwe cholinga chake ndi kuchiza matenda oopsa. Kuphatikizidwa mosamala ndi mankhwala ena, chifukwa izi zimatha kuwonjezera ngozi.

Hypertension ndi yosavuta kupewetsa kuposa kusintha kwachipatala kwa vutolo. Popewa, muyenera kuganizira zakudya zomwe mumadya komanso kukhala ndi moyo wabwino.

Msika wamakono wamankhwala uli ndi mndandanda waukulu wa mankhwala omwe amachepetsa kuthamanga kwa magazi komanso kugunda kwa mtima. Zoyenera kwambiri ndizophatikiza mankhwala omwe amaphatikiza zabwino za mankhwala a magulu osiyanasiyana. Chimodzi mwazida zoterezi ndi Noliprel. Mankhwala ndi othandiza kwambiri pa matenda a ochepa ochepa matenda oopsa.

Noliprel A mapiritsi 5 + 1.25 mg 30 ma PC

Kutulutsa mawonekedwe ndi mankhwala zikuchokera

Mankhwala omwe aperekedwa akupezeka mu mawonekedwe a mapiritsi, ophimbidwa ndi chipolopolo cha zidutswa 14 ndi 30 mu chithuza. Kugwiritsa ntchito mankhwalawa kwa matenda oopsa kumachitika chifukwa cha mapiritsi. Chofunikira kwambiri ndi mchere wa perindopril tert-butyl, womwe uli ndi kuchuluka kwa 2 mg ndi 625 μg ya indapamide. Monga zosakaniza othandizira ndi:

• magnesium wakuba,
• silicon dicoside,
• cellulose
• lactose monohydrate.

Noliprel-Forte ali ndi mulingo wosiyana pang'ono ndipo ali ndi mamiligalamu anayi a mchere wa perindopril ndi mamililita 1.25 a indapamide.

Gawo loyamba la mankhwalawo limatha kuletsa enzyme inayake - ACE, yomwe imatha kukhudza kuthamanga kwa magazi, chachiwiri ndi sulfonamide diuretic. Pamodzi, zimathandizana zochita za wina ndi mnzake, komanso pamlingo wocheperako, amalimbana bwino ndi kukwera kwa chiwopsezo cha intravascular. Palibe vuto pamlingo wamtima, motero mankhwalawa amatha kutengedwa ndi odwala omwe ali ndi bradycardia.

Njira yochizira yodziwika, chifukwa cha kuchuluka kwa mankhwalawa, imawonedwa pokhapokha mwezi ukalandira chithandizo. Kutalika kwa mlingo umodzi ndi tsiku limodzi, kotero mankhwalawa amatha kumwa kamodzi. Chipangizocho sichikuwononga zovuta za metabolism ndipo sichimayambitsa kukula kwa zizindikiro zakuchoka pambuyo pakutha kwa chithandizo. Kutsatira khoma la mtima kumakhala bwino patapita nthawi yayitali.

Noliprel Mndandanda wa Bi-Fort. 10 mg + 2,5 mg 30 ma PC

Contraindication

Atazindikira kupezeka kwa mawonekedwe a mankhwala, dokotala amayenera kuyang'ana wodwalayo kuti apange zotsutsana. Izi zikuphatikiza ndi izi:

• thupi lawo siligwirizana ndi zomwe amapanga,
• kupezeka kwa kulephera kwakanthawi kapena matenda aimpso,
• kukhalapo kwa hepatic encephalopathy,
• matenda a chiwindi
• potaziyamu zokwanira m'magazi a wodwala,
• Zaka za wodwalayo ndizosakwana zaka 18,
• galactosemia,
• shuga malabsorption syndrome.

Njira yogwiritsira ntchito

Noliprel® a forte (Noliprel® a forte)

Mankhwala ayenera kumwedwa ndi matenda oopsa, piritsi limodzi tsiku lililonse m'mawa. Odwala omwe ali ndi vuto la impso ayenera kuyang'aniridwa ndi dokotala. Chisamaliro chiyenera kutengedwa kuti athe kuwunika mtundu wa creatinine chilolezo komanso kuchuluka kwa potaziyamu m'magazi.

Zochita Zosiyanasiyana

Kafukufuku wachipatala omwe amachitika panthawi yovomerezeka ya mankhwala, adawonetsa kukhalapo kwa chiwopsezo cha zotsatirapo zotsatirazi:

• kuchuluka kwambiri
• kupezeka kwa kugwa kwa orthostatic,
• arrhythmias
• mikwingwirima
• kusokonezeka kwa impso,
• kuwonongeka mu potency,
• kusowa kwa chakudya
• nseru
• paresthesia
• kusanza
• kusokoneza kumva, kulawa,

Noliprel - malangizo angagwiritsidwe ntchito

Mawonekedwe a bongo akuphatikiza mawonekedwe a nseru, kusanza, kukula kwa hypotension ndi kulephera kwaimpso. Pankhaniyi, kuchotsedwa kwa mankhwalawa ndi mankhwala ogwiritsidwa ntchito kale ndikusonyezedwa. Chotsani kusweka kwa mankhwala osokoneza bongo ndi dialysis.

Kodi mankhwalawo amakhala

Chimodzi mwazomwe zimaphatikizidwa ndi mankhwala a Noliprel - mapiritsi opanikizika. The achire zotsatira zimaperekedwa ndi magawo awiri yogwira ntchito:

Kupereka zofunikira zaukadaulo zamankhwala, zida zothandiza zimapezeka:

• cellcrystalline mapadi,
• lactose monohydrate,
• magnesium wakuba,
• silika.

Momwe mankhwalawa amachitikira mthupi

Zotsatira zochizira za Noliprel zimaperekedwa ndi zinthu zomwe zimagwira, zomwe zimathandizira kuchitirana.

1. Woyamba wa iwo (perindopril) ndi wa gulu la angiotensin-akatembenuka enzyme inhibitors. ACE inhibitors amachedwetsa kusinthika kwa mphamvu yogwira ya mphamvu ya angiotensin I kukhala yogwira mahomoni angiotensin II, omwe amapanga mitsempha yamagazi ndikuwonjezera kuthamanga kwa magazi. Amalepheretsanso kuwonongeka kwa bradykinin, vasodilator, ndikuchepetsa kuchuluka kwa aldosterone m'magazi, zomwe zimapangitsa kuti magazi azikhala ochepa.

Zotsatira zake, onse a systolic ndi diastolic magazi amachepetsedwa.

Perindopril imapukusanso mitsempha yamagazi, imachepetsa michere yamanzere yamanzere, ndikuyambiranso kunenepa.

1. Indapamide ndi membala wa gulu la okodzetsa. Imalepheretsa kuphatikizidwanso kwa sodium mu mafinya a impso. Zotsatira zake, kuchuluka kwa sodium ndi chlorine kumawonjezeka ndi mkodzo.

Indapamide amadziwika kuti amachepetsa kuthamanga kwa magazi paz Mlingo zomwe sizimathandizira kukodzetsa kwenikweni.

Perindopril ndi indapamide amalowetsedwa mwachangu m'magazi. The bioavailability wa chinthu choyamba ukufika 70%, bioavailability wa indapamide ndi 95 peresenti. Kuchuluka kwa ndende ya indapamide kumachitika ola limodzi pambuyo pakupereka, perindopril - pambuyo maola atatu kapena anayi.

Zinthu zonsezi zimapukutidwa kudzera mu impso.

Ndi matenda ati omwe Noliprel amathandizira?

Mankhwala amagwiritsidwa ntchito pochiza matenda oopsa. Kuzindikira kumeneku kumachitika ngati kupanikizika kwamphamvu kukhale pamtunda wa 140/90 mm Hg. Art. Matenda oopsa amayenera kusiyanitsidwa ndi kuthamanga kwa magazi, komwe kumatha kuonekera pambuyo pa kupsinjika kwamphamvu kapena kutopa. Potere, kupsinjika mwaokha kumabwereranso pamlingo wake woyambayo. Ndi matenda oopsa, kukonza kukakamiza kumatheka pokhapokha mothandizidwa ndi othandizira antihypertensive.

Zotsatira zoyipa za matenda oopsa pakhungu

Chizindikiro cha matenda oopsa chimadalira gawo la chitukuko cha matendawa komanso kuwonongeka kwa ziwalo zina.

1. Pa gawo loyamba, kuthamanga kwa magazi sikudutsa 180/115 mm RT. Art. Thupi lamanjenje lamkati ndi ziwalo sizikhudzidwa pakadali pano.
2. Mu gawo lachiwiri, kupanikizika kumachokera ku 180-210 / 115-125 mm RT. Art. Pali kuchepetsedwa kwa ziwiya za retina, kuwonjezeka kwa kukula kwa lamanzere kwamitsempha yamanzere, ndi ma transistor ischemic. Zovuta zamankhwala zimawonekera.

Ziyeso zimazindikira mapuloteni mumkodzo komanso kukula kwa creatinine m'magazi.

1. Gawo lomaliza la matendawa limadziwika ndi mavuto akulu kwambiri. Kupanikizika kumatha kufika 300/130 mm Hg. Art. Kulephera kwamitsempha yamanzere, ubongo wam'mimba wam'mimba, kusokonezeka kwa ziwiya zam'mimba, kuwala kwa mitsempha ya mtima, komanso kulephera kwa aimpso.

Zovuta za kuthamanga kwa magazi ndi:

• angina pectoris
• vuto la mtima
• sitiroko
• pulmonary edema,
• mphumu wamtima
• aortic aneurysm,
• kuyamwa
• kudzipweteka poyizoni wa thupi chifukwa cha kuwonongeka kwa impso.

Noliprel sangachiritsidwe

• Kugwiritsa ntchito mankhwalawa kumachotsedwa pamene wodwala akudziwitsa zina zake.

Mphamvu ya perindopril mwana wosabadwa mu wachiwiri ndi wachitatu trimesters zingachititse kukula kwa hypotension mu wakhanda, mkhutu ntchito, ndi kuwonongeka mafupa a chigaza. Kutsika kwa kuchuluka kwa madzimadzi amniotic kunadziwika. Indapamide ikhoza kuyambitsa kuchepa kwa fetal.

Ngati kutenga pakati kumachitika nthawi ya mankhwalawa ndi Noliprel, mankhwalawa amachotsedwa.

Kuphatikiza pa kutsutsana mwachindunji, pali zochitika zina zomwe pakufunika kugwiritsa ntchito Noliprel mosamala.

Pali mndandanda wautali wa mankhwalawa omwe amamwa mankhwala omwe ali ndi zovuta zosafunikira, monga kuthothoka kwa kuthamanga kwa magazi, kuphwanya kwamchere wamchere. Izi zimaphatikizira a impso artery stenosis, aortic valve stenosis, systemic lupus erythematosus, shuga mellitus, hyperuricemia.

Anthu omwe akudwala matenda a mtima kapena osayenda mokwanira magazi kupita ku ubongo ayenera kuyamba kulandira chithandizo chocheperako.

Asanayambe kumwa mankhwalawa, odwala okalamba ayenera kuonetsetsa momwe impso imagwirira ntchito komanso kuchuluka kwa potaziyamu m'magazi. Izi ndizofunikira kuchepetsa chiopsezo cha hypotension.

Anthu omwe ali ndi vuto lalikulu la mtima, magazi ochepa, komanso matenda enaake okhala pachiwopsezo ali pachiwopsezo chofanana.

Therapy "Noliprelom" imafuna kuwunika pafupipafupi kuchuluka kwa ma electrolyte apamwamba m'magazi am'magazi (potaziyamu, magnesium, calcium, sodium, chlorine, chitsulo). Chofunika kwambiri ndikuwongolera kotere kwa okalamba ndi omwe afowoka chifukwa cha matenda osiyanasiyana omwe amakakamizidwa kumwa mankhwala ena.

Momwe mungamwere mankhwala

Mankhwala amapatsidwa mankhwala oopsa a madigiri onse. Mlingo wokhazikika kwa akuluakulu ndi piritsi limodzi patsiku.

Mlingo wa okalamba ndiwomwewo. Ndikulimbikitsidwa kumwa piritsi m'mawa.

The achire zotsatira pambuyo makonzedwe ake okhazikika tsiku lonse. Zotsatira zokhazikika zochizira zimatheka mu osakwana mwezi umodzi. Ngati chithandizo chasokonezedwa, palibe njira yobweretsera.

Kodi zotsatila zake zingakhale chiani?

• Amatsimikizika ndi kuyankha kwa thupi ku perindopril ndi indapamide. Gawo loyamba la Noliprel lingayambitse kuchepa kwambiri kwa magazi, kutsitsa orthostatic hypotension. Nthawi zina, angina pectoris, arrhythmia, myocardial infarction, sitiroko samachotsedwa.

Kwamikodzo dongosolo akhoza kuchita ndi kukula kwa pachimake aimpso kulephera, mapuloteni mu mkodzo.

Perindopril angayambitse mutu

Zosiyanasiyana zimachokera ku dongosolo lamanjenje ndizotheka. Izi zimaphatikizapo kufooka ndi kutopa, chizungulire, kupweteka mutu, kusinthasintha, kumva kulira ndi kukwawa, tinnitus, anorexia, mavuto ogona.

Kuuma chifuwa, bronchospasm, kuphatikiza kwamadzi kuchokera pamphuno (kawirikawiri) kumawonedwa.

Zotsatira zoyipa za perindopril pamatumbo am'mimba zimatha kupweteka m'mimba, kutsegula m'mimba kapena kudzimbidwa, nseru, komanso kumva pakamwa pouma. Nthawi zina, kutupa kwa kapamba, intrahepatic cholestasis (kusunthika kwa bile), hyperbilirubinemia (milingo ya bilirubin m'magazi) imayamba.

Mawonekedwe amtundu wa khungu amachepetsedwa makamaka kuyimitsidwa ndi zotupa, urticaria ndi angioedema sichiwonetsedwa.

Kuyesedwa kumatha kuwerengetsa kuchepa kwa kuchuluka kwa hemoglobin ndi mapulateleti.

Zomwe zimatsalira ndikutuluka thukuta kwambiri, kuwonongeka mu potency.

• Zotsatira zoyipa za indapamide pa chapakati mantha amadziwika ndi mutu, chizungulire, paresthesia, kufooka.

Khansa ya m'mphuno, kuyanika kuchokera ku mucosa wamlomo imatha kuonedwa. Pancreatitis ndi hepatic encephalopathy nthawi zina zimakhala zotheka.

Anemia

Dongosolo la hematopoietic limatha kuyankha ndi leukopenia, thrombocytopenia, kuchepa magazi.

Dermatological zotsatira nthawi zambiri zimafotokozedwa mu zotupa za khungu, mawonekedwe a hemorrhagic vasculitis.

Indapamide imatha kuchepetsa kuchuluka kwa sodium, chlorine, komanso nthawi zina potaziyamu. Zokhala ndi sodium yochepa kwambiri zimatha kupangitsa kuchepa kwa magazi kuzungulira magazi, kuchepa kwa madzi m'thupi.

Zoyenera kuchita ngati bongo wambiri?

Ngati, chifukwa cha kudzipereka nokha kapena mwakulakwitsa, kuchuluka kwa Noliprel kumachitika, kuledzera nkotheka. Zizindikiro zake ndi:

• dontho lakuthwa mopanikizika,
• kusanza
• kukhumudwa
• kusowa tulo
• kugunda kwa mtima
• polyuria (mapangidwe a mkodzo wowonjezera) kapena oliguria (kuchepa kwa mkodzo),
• kuphwanya mulingo wamadzi-electrolyte.

Ngati zizindikiro za poizoni wa mankhwala zikuwoneka, muyenera kutsuka m'mimba yanu. Kuti muyeretse m'mimba, muyenera kumwa magalasi asanu kapena asanu ndi limodzi a madzi ofunda ndikuphatikiza ndi koloko kapena mchere. Kuti musambe, muyenera kukanikiza pamizu ya lilime ndi zala ziwiri.

Pambuyo pakusamba, mutha kutenga sorbent (yotsegula kaboni).

Ngati magazi a munthu wapoizidwayo agwa, ayenera kuti azigoneka kumbuyo kwake, miyendo yake itukulidwe, ndikuyika chinthu pansi pawo.

Momwe Noliprel Amalumikizirana Ndi Mankhwala Omwe

1. Mankhwalawa ndi noliprel, osavomerezeka kuti mugwiritse ntchito kukonzekera kwa lithiamu kugwiritsidwa ntchito pochiza manic ndi hypomanic magawo a bipolar, kukhumudwa kwambiri. ACE inhibitors ndi okodzetsa amachepetsa kuchotsa kwa lifiyamu m'thupi, zomwe zingayambitse poyizoni wa thupi ndi mankhwala awa.

Ndi kuledzera kwa lithiamu, matenda osiyanasiyana amanjenje ndi amisala (kugwedeza, kusokonezeka kwa kayendedwe ka kayendedwe, khunyu).

Ngati ndizosatheka kukana mankhwala omwe ali ndi lithiamu, amafunikira kuyang'anitsitsa zomwe zili mkati mwake ndikusintha mawonekedwe othandizira.

1. Kuphatikizidwa ndi mankhwala omwe ali ndi potaziyamu sikwabwino, chifukwa chitukuko cha hyperkalemia sichitha. Mkhalidwe wamtunduwu umabweretsa kusintha kwakukulu muntchito ya mtima, womwe ungawononge moyo wamunthu.
2. Perindopril akhoza kuwonjezera hypoglycemic zotsatira za insulin.
3. Kuyang'anira limodzi ndi mankhwala ena (erythromycin, pentamidine, vincamine, bepridil, halofantrine) kuyenera kupewedwa, popeza kupangika kwa ma arrhythmias owopsa monga pirouette sikutsutsidwa.
4. Zowopsa zomwezi zimakhalapo zikaphatikizidwa ndi mankhwala a antiarrhythmic (quinidine, amiodarone, sotalol).
5. Baclofen yapakati yopumitsa minofu imakulitsa mphamvu ya Noliprel.
6. Zotsatira zofananazo zimapezeka limodzi ndi ma antipsychotic ndi ma antidepressants atatu.
7. Ibuprofen, diclofenac ndi mankhwala ena omwe si a antiidal anti-yotupa, glucocorticosteroids amachepetsa mphamvu ya antihypertensive.

Ngati NSAIDs imatengedwa pamodzi ndi zoletsa za ACE, kuchuluka komwe kumapangitsa Hyperkalemia sikumawonetsedwa. Kuopsa kumeneku kumakhala kwakukulu makamaka pamene wodwala amakhala ndi potaziyamu wocheperako, nthawi yayitali ya QT, komanso bradycardia.

1. Mankhwala omwe amachepetsa potaziyamu m'thupi (ma laxatives, shuga ndi insulin, calcium), mukamayanjana ndi indapamide, angayambitse hypokalemia.

• "Noliprel" amachulukitsa kuwopsa kwa mtima glycosides motsutsana ndi kusowa kwa potaziyamu m'thupi.
• Kusokonezeka kwa impso kumatha kuchitika mukamagwiritsa ntchito zinthu za radiopaque zokhala ndi ayodini.
• The immunosuppressant cyclosporin imatha kuwonjezera magazi a creatinine.

Kuchita kwa mankhwala ndi mankhwala ena

Noliprel sayenera kumwedwa nthawi yomweyo ngati mankhwala omwe ali ndi lithiamu, chifukwa izi zingayambitse kuchuluka kosalamulira kwa seramu lithiamu. Kuphatikiza kwa mankhwalawa ndi ma diuretics omwe amalimbikitsa kusungidwa kwa potaziyamu kungayambitse zotsatira zoyipa komanso ngakhale kufa. Kugwiritsidwa ntchito mosiyanasiyana kwa Noliprel ndi antipsychotic kumatha kugwa pafupipafupi. Kuphatikizidwa kwa mankhwalawa ndi glycosides kumatha kuyambitsa zovuta pamisempha ya mtima. Kuphatikiza ndi metmorphine kumayambitsa mkaka kwambiri metabolic acidosis.

Wogwiritsa Ntchito Mankhwala Ogwira Ntchito Zogulitsa Industrie Noliprel Forte

Kodi ndingalowetse bwanji mankhwalawa?

Ngati ndizosatheka kugula noliprel, ikhoza m'malo ndi analogues. Pakati pawo pali mankhwala odziwika monga awa:

Ali ndi zophatikizira zofanana ndi za Noliprel. Pali zosiyana pang'ono pamndandanda wazinthu zothandizira, chifukwa musanagwiritse ntchito analogues, muyenera kuwerenga mosamala mafotokozedwe ake.

Ma Analogs amasiyana pamtengo, zimatengera dziko lomwe mankhwala ena amapangidwira. "Noliprel" ndi mankhwala othandiza kupewa matenda oopsa. Komabe, sizikulimbikitsidwa kuti mugwiritse ntchito mosagwiritsa ntchito mankhwala chifukwa cha kupezeka kwa contraindication ndi zoyipa.

Zowonjezera pazanema "Noliprel (malangizo ogwiritsira ntchito): ndimankhwala ati ndikakamize?"

Mutha kuphunzira zambiri zokhudzana ndi matenda oopsa kuyambira kanema wotsatira:

Tchuthi ndi malo osungira

Mankhwalawa akupezeka kuti mugulitsidwa, mutha kuwagula ku mankhwala aliwonse amzindawu mumzinda komanso ngakhale pa intaneti, chifukwa simukufuna kulandira mankhwala kuchokera kwa dokotala. Muyenera kusunga mankhwalawo pamalo amdima, osatha kuwongolera dzuwa ndi ana ang'ono pamatenthedwe mpaka madigiri makumi awiri ndi chinyezi chotsika makumi asanu ndi awiri peresenti.

Mtengo wa mankhwala omwe waperekedwa ndiwotsika mtengo, chifukwa mtengo wa zopangira ndi zinthu zofunika sizikukwera. Izi zimapereka mwayi wokhala ndi chithandizo cha nthawi yayitali ngakhale ndi inshuwaransi yoyambira kapena bajeti yaying'ono yamankhwala.

Natalia, wazaka 53

"Ndakwanitsa zaka 50, ndipo pamakhala mavuto. Dotolo adayambitsa Noliprel, ndipo zonse zidakhala monga kale - tinnitus idasowa, kupweteka pamutu kumatha, kwakukulu, ndinamva bwino. Panthawi inayake, zinkawoneka kuti ngakhale panthawi ya chithandizo ndimataya thupi pang'ono ndikudzibweretsa ndekha mawonekedwe ake, momwe ndingathere pazaka zanga. Pang'onopang'ono, zizindikiro zachilendo zinayamba kuonekera - pakamwa pouma, kudzimbidwa. Nditapita kwa dokotala, zonse zidalowa m'malo - mlingo unasinthidwa, zidapezeka kuti ndachepa kwambiri, ndipo muyezo mumawerengeredwa misa ina. "

"Ndimatenga Noliprel m'mawa, apo ayi, mavuto okhala ndi kuthamanga kwa magazi amawonekeranso. Ndimakondwera kwambiri ndi mankhwalawa, chifukwa mtengo wake umakhala wabwino, ndipo palibe mafunso okhudza kutha kwa mankhwalawa. Ndikutenga osagwirizana, chifukwa cha mankhwala amakono sindichita mantha ndi thanzi langa! "

“Kwa nthawi yayitali sindinakhulupirire kuti m'magazi anga makumi anayi ndi kasanu magazi atha kuwonekera. Dotolo adanditsimikizira, ndikufotokozera kuti zomwe zimayambitsa, ndizotheka, ndizovuta komanso zovuta kuntchito. Adandiuza "Noliprel" - zonse zidatha, Ingotenga piritsi limodzi m'mawa. "

"Noliprel" ndi mankhwala a antihypertensive, ali ndi kuphatikiza. Chachilendo chake ndikuti mankhwalawa amakhala ndi magawo awiri a 2 omwe amagwira ntchito mosiyanasiyana nthawi imodzi. Kuphatikizika kwa mankhwalawa kumaphatikizapo perindopril ndi indapamide. Zinthu zake ndi zamagulu osiyanasiyana zamankhwala motsutsana ndi kuthamanga kwa magazi. Gawo loyamba ndi engiotensin-converting enzyme inhibitor, ndipo lachiwiri ndi diuretic. Kuchita molumikizana kwa zinthu izi kumadzetsa kuchepa kwa kuthamanga kwa magazi. "Noliprel" amathandizira kupanikizika pazovuta kwambiri, pamene mankhwala ambiri alibe mphamvu.

Mapiritsi a Noliprel akapanikizika: mawonekedwe, mawonekedwe omasulidwa

"Noliprel" ndi njira yothanirana ndi matenda oopsa. Musanagwiritse ntchito, ndikulimbikitsidwa kuonana ndi dokotala. Pamaziko a kusanthula, mayeso, maphunziro aumoyo wa wodwalayo, adzalembetsa dongosolo la mankhwalawa potengera kuphatikiza kwa mankhwala muyezo woyenera.

Kuti muchiritse bwino matendawa, ndikofunikira kudziwa chomwe chimayambitsa matenda oopsa. Matendawa amayambitsidwa ndi matenda a ziwalo zofunika, kuchepa kwa metabolic m'thupi. Noliprel ndi imodzi mwamankhwala amphamvu kwambiri omwe amagwiritsidwa ntchito pochiza matenda oopsa.

Mapiritsi a Noliprel ndi amodzi a gulu la mankhwala omwe ali ndi antihypertensive mankhwala

Zigawo zikuluzikulu za mankhwalawa:

• Perindopril - 2 mg,
• Indapamide - 0,625mg.

Mankhwalawa adapangira kuti azigwiritsidwa ntchito mu matenda oopsa. Kutengera ndi zomwe dokotala wamulembera, kuthandizira kwa mankhwalawa kumafikira 99%.

Noliprel yokhudza kupanikiza: mitundu ya mankhwala

Noliprel imapezeka m'mitundu ingapo. Mitundu yamankhwala imakhala yosiyanasiyana pazomwe zimagwiritsidwa ntchito pa Perindopril / Indapamide:

• Noliprel - 2mg / 0.625mg,
• Noliprel Forte - 4 mg / 1.25 mg,
• Noliprel A - 2.5mg / 0.625mg,
• "Noliprel" Ndipo kuchokera ku kukakamiza kwa Forte - 5mg / 1.25mg,
• Noliprel A Bi-Fort - 10mg / 2.5mg.

Malinga ndi terminology ya zamankhwala, Noliprel amatanthauza mankhwala ovuta omwe amachepetsa kupsinjika. Mphamvu ya mankhwalawa imachitika pogwiritsa ntchito magawo awiri ogwira ntchito - indapamide ndi perindopril, omwe ali zinthu zosiyanasiyana.

Kupanga ndi mawonekedwe a kumasulidwa

Noliprel (Noliprel) amapezeka m'mitundu ingapo ya mapiritsi. Mawonekedwe awo:

Mapiritsi oyera oblong

The kuchuluka kwa perindopril, mg pa pc.

Mlingo wa indapamide, mg pa pc.

Microcrystalline cellulose, magnesium stearate, colloidal silicon dioxide, lactose monohydrate

Matumba a ma 14 kapena 30 ma PC. m'matumba okhala ndi malangizo ogwiritsira ntchito

Mtengo, ma ruble a 30 ma PC.

Zochita zamankhwala

Perindopril ndi angiotensin-converting enzyme inhibitor, ndipo indapamide ndi diuretic kuchokera ku gulu la sulfonamide. Noliprel imachepetsa kuthamanga kwa diastolic ndi systolic, sikuti kumayambitsa mtima. Zotsatira zamankhwala zimawonedwa patatha mwezi umodzi kuyambira kuyambika kwa makonzedwe. Mchitidwewu ukupitilira kwa tsiku limodzi. Pambuyo pakuyimitsa mankhwala ndi Noliprel, matenda achire samachitika.

Mankhwalawa amathandizira kutha komanso kukhulupirika kwa makoma amitsempha yamagazi. Mankhwalawa samakhudza metabolism, amachepetsa kupanga aldosterone. Kumwa mapiritsi kumachepetsa mwayi wokhala ndi hypokalemia. Limagwirira ntchito ya indapamide ali yemweyo thiazide okodzetsa - kumawonjezera kukodza ndi kwamikodzo excretion wa klorine ndi sodium. Mankhwalawa ndi Noliprel, kuchuluka kwa lipids m'magazi sikusintha, mtima wambiri umachepa mchikakamizo cha adrenaline.

Perindopril imalowa mwachangu, imafikira pa 65% bioavailability, 20% imapangidwa kuti ipange metabolite yogwira ya perindoprilat. Pazitali kwambiri za metabolite m'magazi zimatheka pambuyo pa maola 3-4. Amamangidwa ndi mapuloteni ndi 30%. Hafu ya moyo wa perindoprilat ndi maola 25, imatsitsidwa ndi impso. Okalamba ndi odwala omwe ali ndi mtima, kulephera kwa impso, zotsalira za mlingo zimachotsedwa pang'onopang'ono.

Indapamide imathamanga ndipo imafikika m'mimba kwambiri, ndipo imafika pang'onopang'ono ola limodzi pambuyo pake. Gawoli ndi 79% kuphatikiza ndi albin, theka lake la moyo ndi maola 19. Thupi limapukusidwa ndi impso ndi matumbo, ngati vuto la impso kapena kusakwanira, mankhwala ake a pharmacokinetics sasintha.

Mapiritsi a Noliprel

Malangizowa amalimbikitsa kumwa mapiritsi m'mawa, kamodzi pa tsiku, osatafuna kapena kuphwanya, ndi madzi ambiri. Njira yamankhwala imayikidwa ndi dokotala, koma nthawi zambiri sizikhala ndi malire. Ngati ndi kotheka, adotolo ali ndi ufulu kuwonjezera dokotalayo patapita nthawi, kupereka mankhwala m'malo mwa Noliprel mankhwalawa A, Forte, A forte kapena B forte.

Noliprel A Forte ndi Noliprel Bi Forte

Malangizo ogwiritsira ntchito mapiritsi Noliprel A forte ndi Bi forte sizisiyana ndi kuchuluka kwa mapiritsi. Mankhwalawa amayikidwa kamodzi pa tsiku, makamaka m'mawa. Mapiritsi ayenera kumwedwa nthawi yomweyo, kutsukidwa ndi madzi. Njira yamankhwala sikhala yochepa. Ngati wodwala wachepetsa chilolezo cha creatinine amino acid, ndiye kuti mlingowo sunachepe. Ndi chizindikiro chowonjezeka - munthawi ya mankhwala, mulingo wa potaziyamu ndi creatinine m'magazi umayendetsedwa.

Pa nthawi yoyembekezera

Malangizowa amaletsa kugwiritsa ntchito Noliprel pa nthawi ya pakati kapena poyamwitsa. Kunyalanyaza lamuloli kumaopseza chitukuko cha zotupa ndi matenda mu mwana wosabadwa, zomwe zitha kuchititsa kuti mwana amwalire. Wodwala akakhala ndi pakati panthawi yochizira ndi mankhwalawa, sikofunikira kusokoneza pakati, koma mankhwalawa amaloledwa ndi mankhwala ena, otetezeka a antihypertensive.

Mukamamwa mapiritsi wachiwiri, wachitatu kubadwa kwa mwana, mwana wosabadwayo amapita kukayezetsa matenda ake a impso ndi chigaza. Ngati mayi adamwa mankhwalawa, akhanda angadwavutike ndi matenda owonjezera, omwe amafunika kuwunika thupi lawo pafupipafupi. Pa mankhwala, mkaka wa m`mawere umathetsedwa, kapena mayiyo amapatsidwa mankhwala ena otetezeka.

Kuyanjana kwa mankhwala osokoneza bongo

Malangizo ogwiritsira ntchito akuwonetsa kuyanjana kwa mankhwalawa ndi njira zina. Izi ndizosakaniza ndi zotsatira:

1. Kuphatikizidwa kwa Noliprel ndi kukonzekera kwa lithiamu kumaletsedwa, chifukwa izi zimapangitsa kuti chiwopsezo cha lithiamu m'magazi ndi kawopsedwe.
2. Ndikotheka kumwa mankhwalawa nthawi imodzi ndi potaziyamu osasamala okodzeya kapena othandizira a potaziyamu pokhapokha atapezeka ndi hypokalemia.
3. Kuphatikiza kwa mankhwalawa ndi halofantrine, vincamine, sultoprid kapena bepridil, mtsempha wa magazi a erythromycin kungayambitse arrhythmia, bradycardia.
4. Kuphatikiza kwa insulin ndi Noliprel kumatha kuyambitsa hypoglycemia.
5. Mankhwala osapatsirana omwe amaletsa kutupa amachititsa chidwi cha mankhwalawo. Ndi madzi am'mimba, kuphatikiza koteroko kumatha kupangitsa kulephera kwa impso.
6. Kuphatikizidwa kwa mankhwala omwe ali ndi antipsychotic kapena ma tridclic antidepressants angayambitse hypotension ya orthostatic.
7. Kugwiritsidwa ntchito mosiyanasiyana kwa Noliprel ndi Amphotericin B, mineralocorticoids, Tetracosactide, glucocorticosteroids, mankhwala othandizira othandizira amachititsa kuchepa kwa ma electrolyte am'thupi ndi madzi, zomwe zimabweretsa kukula kwa hypokalemia ndi kuchepa kwa hypotensive.
8. Kuphatikizidwa kwa mankhwalawa ndi mtima glycosides kungayambitse hypokalemia ndi chiwopsezo chowonjezereka cha kawopsedwe.
9. Metformin osakanikirana ndi Noliprel angayambitse lactic acidosis.
10. Musanagwiritse ntchito mankhwala osokoneza bongo a x-ray omwe mumapezeka mankhwala, pamafunika hydrate yokwanira ya thupi.
11. Kuphatikiza kwa mankhwalawa ndi mchere wamchere kumabweretsa kukula kwa hypercalcemia.
12. Kugwiritsa ntchito munthawi yomweyo cyclosporine kumawonjezera kuchuluka kwa creatinine m'magazi.
13. Pa mankhwala ndi Noliprel, mowa umaletsedwa.

Bongo

Mankhwala Noliprel angayambitse bongo pamene mukumwa Mlingo waukulu. Zizindikiro zake ndi: kuchepa kwamphamvu kukakamizika, kusanza, kusanza, kuperewera kwa elekitirodi, chizungulire, kulephera kwaimpso, kusakhazikika kwa mtima. Mankhwala, m'mimba ndimatsukidwa, enterosorbents amatengedwa, madzi osungika a electrolyte amakhala amtundu wina, dialysis imachitika.

Analogs a Noliprel

Mutha kusintha mankhwalawo ndi othandizira ndi mawonekedwe ofanana kapena ofanana, koma ndi ofanana ndi mankhwala. Analogs a Noliprel ndi:

• Co-prenesa - mapiritsi a antihypertensive okhala ndi indapamide ndi perindopril ngati zosakaniza.
• Prestarium - mapiritsi a antihypertensive otengera perindopril, mitundu ina imaphatikizamo indapamide ndi amlodipine.