Mankhwala ORSOTEN - malangizo, ndemanga, mitengo ndi analogi

Orsoten amapangidwa ngati mawonekedwe a makapisozi: kuyambira oyera ndi tint wachikasu mpaka oyera, zomwe zili m'mabotolo ndizosakanikirana ndi ufa ndi ma micCRanules kapena ma microganules ofera loyera kapena pafupifupi loyera, pakhoza kukhala ndi ma proflomerates ambiri omwe amatha kutumphuka mosavuta mukapanikizika (ma PC 7. M'matumba, 3, 6 kapena 12 mapaketi okhala mukatoni, ma pc 21 mu matuza, 1, 2 kapena 4 mapaketi mu bokosi la makatoni).

The kapangidwe 1 kapisozi zikuphatikiza:

• Zogwira ntchito: orlistat - 120 mg (mu mawonekedwe a Orsoten - 225.6 mg),
• Chothandiza: cellcrystalline cellulose,
• Capsule thupi ndi kapu: hypromellose, titanium dioxide (E171), madzi.

Kufotokozera za mankhwalawa

Mankhwala "Orsoten" sikuti amatengeka kulowa mthupi la munthu, motero sadziunjikira m'thupi. Mankhwala onse owonjezera amachotsedwa m'matumbo. Mankhwalawa amagwiritsidwa ntchito ngati njira yochizira odwala onenepa kapena onenepa kwambiri. Kuphatikiza pa mankhwalawa, zakudya zopatsa thanzi komanso zinthu zina zolimbitsa thupi zimatsimikiza.

Mankhwala "Orsoten" ali ndi zotsutsana zina zomwe angagwiritse ntchito:

• kukhalapo kwa biliary kusayenda,
• kupezeka kwa malabsorption osatha,
• mimba
• yoyamwitsa
• osafika pauchikulire

Kugwiritsa ntchito mankhwala Orsoten

Mankhwala "Orsoten" amatengedwa katatu patsiku, kapisozi 1, makamaka, ndi chakudya, pasanathe ola limodzi itatha. Kupitilira makapu atatu patsiku osavomerezeka. Komanso, sibwino kugwiritsa ntchito mankhwalawa mukamadya chakudya popanda mafuta. Kutalika konse kwa mankhwalawa kumatha kufika zaka 2.

Zotsatira zoyipa

Kugwiritsa ntchito mankhwalawa "Orsoten" kumatha kuyambitsa mavuto ena, omwe akuwoneka mwa mawonekedwe ofooka ndikusowa pambuyo pakupita kwa miyezi 1-3 ogwiritsa ntchito mankhwalawa. Zotsatira zoyipa ndizokhudzana ndi zovuta zam'mimba ndi matumbo, zomwe zimatha kupweteka pang'ono m'malo awa. Zotsatira zoyipa zambiri zimaphatikizanso kuchepa kwa shuga m'magazi, matenda opatsirana a ziwalo zina, komanso msambo wa azimayi. Osowa kwambiri, kugwiritsa ntchito mankhwalawa kumayambitsa chifuwa.

Kugwiritsanso ntchito kwa mankhwalawa "Orsoten" ndi zinthu zina kumatha kuyendetsa bwino kapena kuchepetsa mankhwalawa. Pankhaniyi, muyenera kufunsa dokotala kuti njira yochizira ikhale yoyenera.

Mukamachita maphunziro a mankhwala a Orsoten, zakudya zomwe zimapangidwira wodwalayo ziyenera kutsatiridwa potengera zomwe zili ndi zopatsa mphamvu zochepa komanso zopatsa thanzi.

Zizindikiro zogwiritsidwa ntchito

Orsoten amadziwika kuti azitha kuchiza kwa odwala omwe ali ndi kunenepa kwambiri chifukwa cha kuchuluka kwa thupi (BMI) ≥30 kg / m 2 kapena onenepa kwambiri (BMI ≥28 kg / m 2), kuphatikiza odwala omwe ali pachiwopsezo chokhudzana ndi kunenepa kwambiri, kuphatikiza ndikutsatira koyenera Zakudya zochepa zopatsa mphamvu.

Ndikotheka kupatsa Orsoten nthawi yomweyo mankhwala a hypoglycemic komanso / kapena zakudya zochepa zopatsa mphamvu zamagulu 2 a shuga onenepa kwambiri kapena onenepa kwambiri.

Contraindication

• Cholestasis
• Matenda a malabsorption,
• Mimba ndi mkaka wa m'mawere (yoyamwitsa),
• Zofika zaka 18 (chitetezo ndi mphamvu ya Orsoten ya m'badwo uno wa odwala sizinaphunzire),
• Hypersensitivity mankhwala.

Pulotic zochita za Orsoten

Mankhwala a Orsoten slimming ndi gastrointestinal lipase inhibitor omwe amakhala ndi zotsatira zokhalitsa. Kupanga mgwirizano wophatikizika ndi chapamimba ndi matumbo lipases, orlistat imathandizira mu lumens pamimba ndi matumbo ochepa. Chifukwa chake, enzyme yovutayo imataya mphamvu yake yophwanya mafuta azakudya mu mawonekedwe a triglycerides mu monoglycerides ndi mafuta acids aulere.

Popeza ma triglycerides samatengeka mu mawonekedwe osayenera, kudya calorie kumachepa, ndipo kuchepa kwa thupi kumachitika.

Mankhwala ali ndi zochizira popanda kulowa mu kayendedwe kazinthu.

Mankhwalawa amachititsa kuwonjezeka kwa mafuta mu ndowe masiku 1-2 atatha kudya.

Zolemba za Orsoten

Mankhwala a gulu la m'mimba lipase zoletsa. Amathandizira kuthandizira kunenepa kwambiri kwa odwala omwe ali ndi cholozera cha misa pamtunda wa 27 mayunitsi. Kuchita bwino kwa mankhwalawa kumangowonjezereka kokha pakudya zakudya zama calorie ochepa. Makamaka kuchepa thupi kwambiri kumawonedwa m'miyezi itatu yoyambirira ya mankhwala. Kuchuluka kwakukulu kwa gawo lalikulu kumatheka patsiku la 3.

Njira yamachitidwe

Mankhwalawa amapangidwira zochizira zovuta za metabolic, zomwe sizingabwezeretsedwe kudzera mu maphunziro ndi zakudya. Makapisozi ali ndi:

• yogwira pophika - orlistat 120 mg,
• wothandizira - mapiritsi a kristalo wabwino.

Zotsatira zamankhwala zimakhazikitsidwa popewa kuyamwa kwa mitundu yonse ya mafuta m'matumbo, kuphatikiza osinthika. Izi ndichifukwa cha njira zotsatirazi:

• pali kuponderezedwa kwa kumatulutsidwa kwa michere ya lipase m'mimba ndi kapamba,
• chimbudzi chimachitika popanda kuphatikiza mafuta ogawa, omwe ali gawo la zakudya,
• Zinthu zamafuta zovuta sizitha kulowa mu magazi kudzera m'matumbo, popeza sizinapangidwe ndi ma enzyme,
• Zotsatira zake, mafuta osasamba omwewo amachotsedwa m'thupi la munthu ndowe.

Chifukwa chake, mankhwalawa amakhudza kwambiri kunenepa.

Kuphatikiza apo, kugwiritsa ntchito mankhwala pafupipafupi kumathandizira kuti magazi a cholesterol azikhala bwino, omwe ndi othandiza kwa odwala omwe ali ndi ziwalo zam'magazi a mtima.

Kusiyana kwakukulu pakati pa mankhwala osokoneza bongo

Chodabwitsa cha mankhwalawa ndikuchepetsa kuyamwa kwa zinthu zamafuta ndi thupi, zomwe zimathandiza kutaya kilogalamu yowonjezera.

Pali zambiri zofanana pakati pawo kuposa kusiyana. Chifukwa chake, anthu ambiri amaganiza za kusiyana pakati pa Orsoten ndi Orsoten Slim.

Chizindikiro chokha chaopanga mankhwala ndi zomwe zili pazomwe zimapangira kapangidwe kake. Ku Orsoten, kugwiritsidwa ntchito kwa zinthu kumakhala kochulukirapo kawiri, zomwe zikutanthauza kuti zotsatira za mankhwalawa ndizapamwamba.

Malingaliro a madotolo

Nutritionists amakhulupirira kuti pochiza kunenepa kwambiri, mutha kuchita popanda mankhwala. Komabe, akatswiri omwewa samakana mapindu a kumwa mankhwala kuti achepetse thupi. Komabe, izi zimagwira ntchito kwa anthu onenepa (BMI woposa 30).

Palibe dokotala amene anganene kuti ndi ndani mwa ma pharmacological omwe amathandizadi. Onsewa akuyenera kukhala abwino.

Chinthu chachikulu ndikutsatira malangizowo kenako zotsatira za kumwa mankhwala sizingakupangitseni kuti muyembekezere:

• Ndikofunika kuyang'anira cholozera cha misa. Ndizizindikiro za BMI zomwe zimapereka chidziwitso pakugwiritsa ntchito mankhwalawo kapena ayi. Malinga ndi izi, adotolo amawona ndi kupereka mankhwala ofunikira a chinthucho.
• Chofunikira mukamamwa mankhwalawa ndikutsatira zakudya zoyenera. Kusakhalako kwa izi sikungapereke zotsatira zomwe zikuyembekezeredwa kwa nthawi yayitali, ndipo ndalama zimawonongeka.
• Therapy yochokera lipase inhibitors imakhudzanso kuyamwa kwa mavitamini osungunuka a mafuta pazakudya. Nutritionists amalimbikitsa kuphatikiza multivitamini mu zakudya zanu kuti mupewe zovuta zomwe zimapangitsa kuti mavitamini azitha. Kuphatikiza apo, kudya kwawo kuyenera kuchitidwa asanagone, mphamvu ya orlistat itachepa.
• Mbiri ya matenda ashuga iyenera kuganiziridwanso mukamalandira chithandizo. Kumwa mankhwala omwe amalimbikitsa kuchepa thupi, kumaphatikizapo kukonza kagayidwe, kamene kamatha kupereka zotsatira zabwino pa kapamba. Pankhaniyi, kudalira kwamankhwala omwe amachepetsa shuga, kuphatikiza insulin, kusintha. Malangizo omwe amathandizidwa ndi endocrinologist mu nkhaniyi amayamba kuwongolera. Izi zikugwiranso ntchito kwa odwala omwe ali ndi vuto la atherosulinosis komanso matenda oopsa.
• Ngati wodwalayo akuthandizidwa ndi mankhwala ena (anticoagulants, antiarrhythmic mankhwala, etc.), musanayambe makonzedwe a orlistat, muyenera kufunsa katswiri.
• Mankhwala osokoneza bongo amatha kuchepetsa zotsatira za mapiritsi a mahomoni omwe amaletsa kutenga pakati. Chifukwa chake, njira zina zakulera zikuyenera kuunikidwanso.

Kusiyanako ndizomwe zili pazinthu zazikulu chifukwa cha njira yomwe wodwalayo amafikira. Odwala omwe ali ndi digiri yoyamba adzayatsidwa mankhwala omwe ali ndi orlistat yochepa. Woopsa milandu, mlingo wa zinthu umachuluka.

Kuzindikiritsa kuwonetsa kwa zoyipa imodzi mwazomwe amamwa kumathetsa onse, popeza mu zonse ziwiri ndizofanana.

Kartotskaya V.M., gastroenterologist:

Orsoten ndiwothandizira wanga polimbana ndi kunenepa kwambiri. Kuphatikiza apo, odwala sanadandaule, koma okha amabwera ndikusangalala ndi kupambana kwawo.

Artamanenko I.S., dotolo:

Orsoten Slim, ngakhale ili ndi zovuta, koma imathandiza. Ngati muchita mosamalitsa malinga ndi zomwe mwalangizidwazo ndipo simukuphwanya zakudya, palibe zovuta zomwe zingamutsatire.

Ndemanga Zahudwala

Odwala amadziwa bwino kusiyana pakati pa Orsoten ndi Orsoten Slim. Kupatula apo, amadzakumana ndi zovuta komanso zoyipa zilizonse zomwe zimachitika chifukwa cha ma pharmacological. Ndipo chimenecho ndi chowonadi.

Anthu ambiri amakonda kugula Orsoten, chifukwa imapereka chitsimikizo komanso imachepetsa chiopsezo cha mavuto.

Maganizo pa ntchito ya odwala matenda ashuga Slim amagawidwa. Ena amazindikira kuwonongeka m'moyo wabwino, ena amangogwiritsa ntchito mavuto, osanena za kusiyana kwa mndandanda.

Malinga ndi ndemanga, titha kunena kuti woyamba mankhwala ali ndi chidaliro pakati pa ogula kuposa chachiwiri. Izi ndichifukwa cha mtengo wotsika mtengo, mawonekedwe owoneka a mankhwalawo.

Valeria, wazaka 32

Orsoten adandithandiza kuchotsa mapaundi owonjezera, ngakhale ndidangomaliza theka la maphunziro. Ndidapenda zakudya zanga ndidayamba kuchita maphunziro akuthupi. Zovala zanga zidakhala zabwino kwambiri.

Nditabereka, ndinayamba kulimba mtima. Wodwalayo adalamulira Orsotin Slim. Kulemera kwanga ndikadachepa kwambiri. Komabe, poyamba ndinali ndi nkhawa za ndowe zamafuta, koma kenako ndinazolowera izi.

Chifukwa chake, kusankha kwa mankhwala kumadalira umunthu wa munthu ndipo ndi dokotala yekhayo amene angadziwitse.

Mlingo ndi makonzedwe

Orsoten amatengedwa pakamwa ndi madzi.

Mlingo umodzi wovomerezeka ndi 120 mg (1 kapisozi). Mankhwalawa amayenera kumwedwa ndi chakudya chachikulu chilichonse (musanadye chakudya, mukamadya kapena mkati mwa ola limodzi mutatha kudya). Orsoten amatha kutsetsereka ndikamadumphira zakudya kapena ngati zakudya sizikhala ndi mafuta.

Kumwa mankhwalawa tsiku lililonse kuposa zopitilira 360 (makapisozi atatu) sikuti kumathandizanso pakuchiritsa. Kutalika kwa maphunziro - osapitilira zaka ziwiri.

Pazovuta za impso kapena chiwindi, komanso odwala okalamba, kusintha kwa mankhwala sikofunikira.

Zotsatira zoyipa

Nthawi zambiri, mukamamwa Orsoten, matenda am'mimba am'mimba amayamba chifukwa cha kuchuluka kwa mafuta mu ndowe. Nthawi zambiri, matendawa amakhala ofatsa komanso osakhalitsa m'chilengedwe ndipo amakula pakatha miyezi itatu yoyambirira. Ndi chithandizo cha nthawi yayitali, zotsatira zamavuto zimachepa.

Pogwiritsa ntchito Orsoten, zovuta zotsatirazi zimatha:

• Dongosolo logaya chakudya: kulimbikitsani kuti musiyeni, kukhathamira ndi zotuluka ku rectum, mafuta okukhazikika / mafuta onunkhira, zotupa zamafuta kuchokera ku rectum, zotayirira komanso / kapena zofewa, steatorrhea (kuphatikiza mafuta mu chopondapo), kusapeza bwino komanso / kapena kupweteka pamimba ndi mu rectum, fecal incontinence, kuchuluka kwamatumbo, kufunikira kozama, kuwonongeka kwa mano, mano, kawirikawiri - matenda amtundu, diverticulitis, hepatitis (mwina yoopsa), kuchuluka kwa phosphatase ya alkaline ndi transaminases ya chiwindi,
• Metabolism: hypoglycemia (yokhala ndi matenda a shuga a 2)
• Pakati mantha dongosolo: nkhawa, mutu,
• Thupi lawo siligwirizana: kawirikawiri - angioedema, kuyabwa, urticaria, zidzolo, anaphylaxis, bronchospasm,
• Khungu: kawirikawiri kwambiri - zotupa zamphongo,
• Zina: kumva kutopa, dysmenorrhea, matenda ofanana ndi chimfine, matenda am'mimba opumira ndi ziwalo zamkodzo.

Malangizo apadera

Orsoten imagwira ntchito kwa nthawi yayitali yoongolera thupi (kuchepetsa thupi, kuisunga pamlingo woyenera ndikuletsa kupewa kuwonjezeranso thupi). Chithandizo cha mankhwalawa chimawongolera chiwonetsero cha zovuta ndi matenda omwe amayenda ndi kunenepa kwambiri (kuphatikizira kulekerera kwa glucose, hypercholesterolemia, matenda oopsa, hyperinsulinemia, mtundu 2 shuga mellitus), ndikuchepetsa kuchuluka kwamafuta a visceral.

Chifukwa cha kuchepa thupi kwa odwala omwe ali ndi mtundu wa matenda a shuga 2, kusintha kwa chiphuphu cha carbohydrate metabolism nthawi zambiri kumawonedwa, komwe kungapangitse kuchepa kwa mlingo wa mankhwala a hypoglycemic.

Pa mankhwalawa, tikulimbikitsidwa kuti mutenge maultivitamini osiyanasiyana kuti muwonetsetse kuti muzikhala ndi zakudya zokwanira.

Odwala ayenera kutsatira malangizo azakudya. Zakudya ziyenera kukhala zopatsa mphamvu, zopatsa mphamvu pang'ono komanso zopatsa mphamvu zopitilira 30% zamafuta. Zakudya za tsiku ndi tsiku zamafuta ziyenera kugawidwa m'magulu atatu akuluakulu.

Chiwopsezo cha zotsatira zoyipa zamagetsi chimatha kuchuluka mukamamwa Orsoten motsutsana ndi zakudya zamafuta.

Mankhwalawo amathetsedwa ngati, mkati mwa masabata 12 kuyambira pomwe mankhwalawa adayamba, kulemera kwa thupi sikunatsike kupitilira 5% ya choyambirira.

Kuyanjana kwa mankhwala osokoneza bongo

Ndi kuphatikiza kwa Orsoten ndi mankhwala ena, zotsatirazi zingachitike:

• Warfarin kapena ma anticoagulants ena: kuwonjezeka kwa INR, kuchepa kwa prothrombin, kusintha kwa magawo apamwamba kwambiri,
• Pravastatin: kuwonjezeka kwake kwa plasma, bioavailability ndi lipid-kutsitsa mphamvu,
• Mavitamini osungunuka a mafuta (A, D, E, K): kuphwanya mayamwidwe awo (kukonzekera kwa multivitamin ndikulimbikitsidwa kuti kumatengedwe musanagone kapena osapitilira maola 2 mutatha kumwa Orsoten),
• Cyclosporine: kuchepa kwa kuchuluka kwake m'madzi am'magazi (tikulimbikitsidwa kuti muthane ndi msinkhu wake),
• Amiodarone: kuchepa kwa kuchuluka kwake m'magazi am'magazi (kuwunika mosamala zamankhwala ndikuwunika kwa electrocardiogram ndikofunikira).

Chifukwa cha kusintha kwa kagayidwe kachakudya matenda ashuga, kusinthaku kwa mankhwalawa ofunikira pakamwa kungafunike.

Kugwirizana kwa Orsoten ndi ethanol, digoxin, amitriptyline, biguanides, kulera kwapakamwa, fibrate, furosemide, fluoxetine, losartan, phentermine, phenytoin, nifedipine (kuphatikizapo kuchedwa kutulutsidwa), captopril, atenobenol.

Bongo

Ndemanga za madotolo ku Orsoten zilibe chidziwitso chokhudza milandu yambiri ya chida ichi.

Mlingo umodzi wa orlistat pa mlingo wa 800 mg kapena mpaka 400 mg katatu patsiku kwa milungu iwiri sizinayende limodzi ndi zovuta zoyipa.

Ngati bongo wa mapiritsi a Orsoten, kuyang'anira wodwala tsiku lonse ndikulimbikitsidwa.

Mimba komanso kuyamwa

Sitikulimbikitsidwa kupatsa Orsoten pa nthawi yomwe muli ndi pakati, popeza palibe zambiri zakuchipatala pakugwiritsa ntchito mankhwalawa odwala.

Zomwezi zimagwiranso ntchito pakugwiritsa ntchito mapiritsi a Orsoten panthawi yoyamwitsa (zambiri sizikupezeka).

Kuchita ndi mankhwala ena

Mukamagwiritsa ntchito Orsoten nthawi yomweyo ndi:

• warfarin ndi ma anticoagulants ena - mulingo wa prothrombin umachepa, INR imawonjezera, ndipo, chifukwa, kusintha kwa magawo a hemostatic
• pravastatin - kukhudzika kwake kwachilengedwe komanso kutsitsa kwa lipid kumachulukitsa,
• mavitamini osungunuka mafuta - K, D, E, A - mayamwidwe awo amasokonezeka. Chifukwa chake, mavitamini ayenera kumwedwa asanagone kapena maola awiri mutatha kumwa Orsoten.
• cyclosporine - kuchuluka kwa cyclosporin mu plasma kumachepa. Pamenepa, kuwunika pafupipafupi kuchuluka kwa cyclosporin m'magazi kumalimbikitsidwa.

Tiyeneranso kukumbukira kuti kuchepa thupi kumatha kuwongolera kagayidwe kachakudya kwa odwala matenda ashuga. Chifukwa chake, m'gulu ili la odwala, kuchepetsa mankhwalawa kwa mankhwala a hypoglycemic angafunike.

Odwala omwe amagwiritsa ntchito amiodarone amafunikira kuwunikira mosamala ECG, chifukwa pakhala pali milandu yotsika ya amiodarone m'magazi.