Zotsatira ndi thandizo la insulin

Insulin Chronic overdose Syndrome (SHPI, chodabwitsa (matenda), rebound hyperglycemia, posthypoglycemic hyperglycemia) - mu 1959, pakuwunika mwachidule zotsatira za zomwe anthu ambiri apenda, wasayansi waku America a Michael Somogyi (Wachingelezi Michael Somogyi) adapanga lingaliro ponena za kupezeka kwa zinthuzi posthypoglycemic hyperglycemia (kuyambitsa kwa kuchuluka kwa insulin kumabweretsa hypoglycemia, yomwe imalimbikitsa kubisalira kwa mahomoni a contrainsulin ndi rebound hyperglycemia - poyankha kuchuluka kwa shuga m'magazi). Nthawi iliyonse masana, kuchuluka kwa insulin m'madzi a m'magazi kumakhala kokwanira kuposa momwe amafunikira, komwe kumayambitsa hypoglycemia (yomwe sikuti imadziwika nthawi zonse ndi odwala) kapena kudya kwambiri. Kutulutsidwa kwa mahomoni a contrainsulin pa nthawi ya mankhwala a insulin kumabweretsa kusintha kwakukulu pakuphatikizidwa kwa shuga m'magazi am'magazi, zomwe zimapangitsa kusakhazikika kwa mtundu wa 1 shuga kwa odwala ambiri. Kuchulukitsidwa kwotalikira kwa mahomoni a contrainsulin kumabweretsa kukula kwa ketonuria ngakhalenso ketoacidosis.

Kuchuluka kwa insulini kumabweretsa bongo zochuluka bwanji

Mlingo wotetezeka kwa munthu yemwe alibe matenda ashuga ayenera kupitilira 4 IU. Ochita masewera olimbitsa thupi, makamaka omanga thupi, nthawi zina amagwiritsa ntchito timadzi tambiri tambiri, kukulitsa gawo lovomerezeka kasanu. Anthu odwala matenda ashuga pazamankhwala angagwiritse ntchito 25 mpaka 50 IU ya insulin.

Chilichonse choposa izi zimatsogolera ku bongo.

Nthawi zambiri, zifukwa za izi ndi zolakwika pamakina, kuyambitsa kamodzi kolakwika, kuyenda kukakonzekera, kapena kusakwanira kwa katswiri. Zingathenso kutsogolera bongo:

• kuphwanya magwiridwe anthawi zonse ogwiritsidwa ntchito ndi mafuta osakwanira,
• kukana kudya pambuyo pa insulin,
• kusintha kwa mtundu wina wamagulu amthupi,
• Mankhwala olakwika kwa munthu wathanzi,
• kusagwirizana ndi malingaliro azachipatala.

Kuphatikiza apo, kugwiritsa ntchito insulin yochulukirapo ndikotheka ndikugwiritsa ntchito nthawi yomweyo insulin, kugwiritsa ntchito mowa wambiri. Makamaka, zotsatira zoyipa ziyenera kuyembekezedwa ngati munthu wodwala matenda ashuga samatha kudya pophwanya masewera olimbitsa thupi.

Zoyambitsa bongo

Mukamasankha kuchuluka kwa mankhwalawa, kuchuluka kwa shuga mumagazi kumawerengedwa.

• kuyambitsa mahomoni kwa munthu wathanzi,
• kusankha kosayenera kwa endocrinologist,
• kudzisankhira nokha mankhwala
• kusinthira ku mtundu wina wa mankhwala, pogwiritsa ntchito ma syringe akuluakulu,
• kuyambitsa kwa mankhwala mu minofu, osati pansi pa khungu.
• kuchuluka kwa zolimbitsa thupi ndi kuperewera kwa chakudya chamafuta omwe amapezeka pambuyo pa jekeseni,
• munthawi yomweyo kumwa insulin,
• kuchuluka yopuma pakati chakudya.

• m'mimba
• kulephera kwa aimpso,
• ndi matenda a chiwindi (kuchepa kwamafuta, hepatitis),
• Poika mankhwala opaleshoni ya wodwalayo (wodwalayo ayenera kudziwitsa wodwalayo asanabadwe za matenda a shuga omwe amadalira insulin, omwe angathandize kuwerengera moyenera mankhwala oletsa kuperewera),
• mutamwa mowa (odwala matenda ashuga samalimbikitsidwa kumwa mowa, komabe, ngati wodwalayo wasankha kutenga choopsa, ndikofunikira kuchepetsa kuchuluka kwa insulini yoyendetsedwa).

Zizindikiro za insulin yowonjezera

1. Choyamba. Matenda a wodwalayo akuipiraipira patatha mphindi zochepa atayambitsidwa mahomoni. Zizindikiro zake zimaphatikizaponso kufooka, tachycardia, kupweteka pamutu, kuchuluka kwambiri kwa chilakolako cha chakudya.
2. Lachiwiri. Pakakhala chithandizo choyamba, kupendekera ndi kunjenjemera kwa miyendo yayikulu kumachitika. Kutopa kumakulirakulira, kufooka kwa minofu kumachuluka. Matenda a wodwalayo amachepa, ndipo kukula kwa ana amakula.
3. Chachitatu. Kufooka kumayamba kutchulidwa kwambiri, wodwala amataya mwayi wodziyimira pawokha. Thukuta lakuzizira limatulutsidwa zochuluka. Kugunda kumawonjezereka ndipo kumangokhala kwapamwamba. Nthawi zambiri chikumbumtima chimatha. Kuwonongeka kwa dongosolo lamanjenje kumayendetsedwa ndi kuphwanya zochitika zamaganizidwe.
4. Chachinayi. Ndi dontho lowopsa la glucose m'magazi, khungu la wodwalayo limasinthasintha, kugunda kwa mtima kumachepa kwambiri. Kukula kwa ana kumaleka kusintha motsogozedwa ndi kuwala. Wodwalayo amagwa.

Zizindikiro zake

Mlingo womwe zizindikilo zimakhazikika zimadalira mtundu wa mankhwala omwe agwiritsidwa ntchito. Mwachitsanzo, ndikuyambitsa insulin yofulumira, zizindikiro zimayamba pakapita nthawi yochepa, ndikugwiritsa ntchito pang'onopang'ono - kwa nthawi yayitali.

Pa gawo loyamba lachitukuko cha boma, kumverera kwanjala, kufooka kwathunthu kumakhazikitsidwa. Odwala matendawa amawonetsanso mutu komanso kuthamanga kwa mtima. Ngati panthawiyi palibe njira zomwe zachitidwa kuti zikuwonjezere shuga m'magazi, ndiye kuti chithunzi cha chipatala chimathandizidwa ndi thukuta, manja akunjenjemera, malovu owonjezera. Palibenso zodziwika pang'ono zowonetsa kufooka kwapang'onopang'ono ndi kumverera kwanjala, kufooka kwakukulu, dzanzi la zala. Kudutsa zowonongeka komanso ana opukusidwa amatha kuzindikirika. Tiyenera kudziwa kuti padakali pano boma lisintha.

Owerenga mabakera anena zowona zonse zokhudza matenda ashuga! Matenda a shuga amapita pakatha masiku 10 ngati mumamwa m'mawa. »Werengani zambiri >>>

Komabe, pambuyo pake, mkhalidwe wa odwala matenda ashuga udzakulirakulira mwachangu. Chithunzi cha chipatala ndi motere:

1. Zofooka zimapita patsogolo, chifukwa cha ichi, munthu sangathe kudzithandiza okha.
2. Kulephera kusuntha, thukuta kwambiri, komanso zolimbitsa mtima zimadziwika. Kugwedezeka kwa malekezero akumwamba ndi otsika, kuchuluka kwa chikumbumtima, kupsinjika, kapena, kugwedezeka kwamaganizidwe kwambiri kungachitike.
3. Kenako kuphatikizika kwa clonic (kupindika) kapena kupweteka kwa tonic. Ngati shuga saperekedwa m'mitsempha pakalipano, kuyambika kwa hypoglycemic coma kungakhale kotheka.
4. Kukomoka kumadziwika chifukwa cha kusazindikira, kuchepa kwamphamvu kwa shuga m'magazi (kupitirira mamililita asanu kuchokera munthawi yomweyo). Pa matenda ashuga, osasinthika, chiwonetsero cha mtima, komanso kusakhalapo kwa wophunzira kumadziwika. Sitikukayikira kuti zotulukapo za izi zitha kukhala zoopsa kwambiri.

Etiology

Pambuyo pakugwiritsa ntchito bwino kwa insulin kukonzedwa ndi Frederick Banting ndi Charles Best (1922), kafukufuku wokwanira wazomwe zimachitika pochita nyama ndi anthu zidayamba. Zinapezeka kuti kuyang'anira milingo yayikulu ya insulin imayambitsa kukula kwa "hypoglycemic" kwambiri "mwa nyama, zomwe nthawi zambiri zimatha mu Cannon W.B. et al., 1924, R>. Akatswiri azinthu zanyama za nthawi imeneyo, potengera zotsatira za kafukufuku wambiri, adanenanso za kuyipa kwakulu chifukwa cha kuchuluka kwa mahomoni pachinthu chamoyo. Inapezeka ndi Clark B.B. et al., 1935 kuti kugwiritsidwa ntchito kwa Mlingo waukulu wa insulin pofuna kuonjezera kuchuluka kwa odwala omwe ali ndi anorexia amanosa kunapangitsa kuti magazi asinthe kwambiri kuyambira patsiku la hypo-to hyperglycemia masana, kuwonekera kwa kupindika kwa matenda a shuga ndi zizindikiro za matenda ofupika a shuga kumapeto. Njira ya mankhwala.

M. Odin et al. (1935), yemwe adapereka ma insulin 40 katatu patsiku kwa odwala omwe ali ndi anorexia manthaosa, adazindikira zoopsa zomwe zimachitika pakatha masabata awiri atatha maphunziro awo. J. Goia et al. (1938) adawona kusinthika kwa glycemia kuchokera ku hypo- kupita ku hyperglycemia atatha jakisoni imodzi ya insulin.

Mkulu hyperglycemia ndi glucosuria pambuyo hypoglycemia amawonekera mu matenda a mankhwalawa odwala a schizophrenia ndi insulin mantha, komanso anthu a pancreatic islet beta cell tumors (insulinomas), limodzi ndi zochitika za hypoglycemia. Odwala ambiri, atachotsa insulinoma, adawonetsanso zizindikiro za matenda osakhalitsa a mellitus Wilder R.M. et al., 1927, Nankervis A. et al., 1985.

Chodabwitsa cha zachilendo kuwonjezereka kwa glycemia chifukwa cha kuchuluka kwa insulin kutumikiridwa zimanenedwanso mu chithandizo cha odwala matenda a shuga. Ambiri a E.P. Joslin mu 1922 pofupikitsa zotsatira zoyambirira za mankhwala a insulin, adawonetsa kuchuluka kwa glycemia wodwala yemwe ali ndi matenda osokoneza bongo omwe ali ndi kuchuluka kwa insulin. Popanda chidziwitso chokwanira, adaletsa insulini mosamala kwambiri - mwa ambiri omwe adawawona, kubwezeretsa kokwanira kwa kagayidwe kazomwe zimachitika ndikuyambitsa magawo 11 a insulin yochepa patsiku (makamaka asanadye).

Sinthani ya Etiology |Kodi pamafunika insulin ingati pa mankhwala osokoneza bongo?

Kwa munthu wamkulu (i.e., wopanda matenda ashuga), mlingo wabwino wa insulin ndi magawo 2-5.

Nthawi zambiri, omanga thupi, kuyambira ndi otetezeka, pang'onopang'ono amawonjezera mlingo, amabwera ndi magawo 20.

Mu shuga mellitus, mlingo wa insulin umasankhidwa payekha ndi endocrinologist, poganizira kuchuluka kwa shuga mu seramu ya magazi ndi kukhalapo kwa shuga mkodzo. Achire achire mlingo wa shuga ali osiyanasiyana 2040 mayunitsi, mu milandu kwambiri kapena kukula kwa zovuta (hyperglycemic chikomokere), akhoza kuchuluka, ndipo kwambiri.

Zomwe zimayambitsa kuchuluka kwa insulin ndi:

• Mulingo wosankhidwa bwino wa mankhwala okhala ndi insulin,
• zolakwika nthawi ya jakisoni, yemwe nthawi zambiri amawonedwa mukasinthira mankhwalawa kapena kugwiritsa ntchito syringe yatsopano.
• intramuscular (m'malo mwa subcutaneous) makonzedwe,
• Kudumpha chakudya pambuyo pa jekeseni,
• mphamvu yayikulu yolimbitsa thupi ndi osakwanira kudya pambuyo pa jakisoni.

Mikhalidwe ina imakulitsa chidwi chathupi kumanga insulin. Izi zikuphatikiza:

• mafuta amchiwindi,
• aakulu aimpso kulephera
• trimester yoyamba ya mimba
• mkhalidwe woledzera (kuphatikizapo wofatsa).

Milandu imeneyi, ngakhale kukhazikitsidwa kwa mankhwala osankhidwa ndi adokotala kungayambitse kukula kwa zizindikiro za insulin.

Zotsatira za kuchuluka kwa insulin

Munjira zambiri, zotsatira zake zimadalira kuchuluka kwa momwe angachitire. Chifukwa chake, onse odwala matenda ashuga amakumana ndi zovuta za hypoglycemic. Malinga ndi kuchuluka kwa zamankhwala, pafupifupi 30% ya odwala amakhala ndi hypoglycemia ndi zotsatira zake. Choopsa chachikulu chili pakupanga Somoji syndrome, yomwe idzafotokozeredwe pambuyo pake. Zotsatira zake, zimatchedwa chithandizo chosayenera cha matenda osokoneza bongo, omwe samathandizira njira ya matendawa ndipo pakapita nthawi zimayambitsa ketoacidosis.

Zotsatira zake ngati vuto lachiwopsezo cha hypoglycemia liyenera kuthetsedwa mwa kukhazikitsa mankhwala oyenera. Izi nthawi zambiri zimatenga nthawi yayitali. Woopsa milandu, kuchuluka kwa insulin kungayambitse kusokonezeka mu zochitika zamanjenje:

• kutupa muubongo,
• Zizindikiro za meningeal (kupweteka mutu, kuwopa kuwala, kusanza mseru komanso kusanza kotulutsa, minofu yolimba ya khosi),
• ntchito zamavuto amisala, monga dementia.

Ngati munthu wodwala matenda ashuga pazifukwa zina amakonda kubwereza machitidwe a hypoglycemic ndipo ngati pali vuto la mtima, kusokonekera kwa myocardial infaration ndikotheka. Komanso, wodwalayo atha kudwala matenda otupa komanso otupa.

Kuopsa kwa insulin yambiri

Insulin ndi timadzi tomwe timatulutsa timaselo tating'ono tating'ono. Zowopsa za kapamba. Ili ndi luso lotha kuyendetsa kagayidwe kazakudya, imathandizira kutulutsa minofu ndikuwonjezera kutembenuka kwake kwa glycogen. Insulin ndi wothandizila wina wodwala matenda ashuga. Timalowetsedwa m'thupi, timachepetsa shuga m'magazi, timachepetsa kuphipha kwake mu mkodzo, timachotsa zotsatira za matenda a shuga.

Ngati mankhwala osokoneza bongo a insulin kwambiri komanso kudya kwadzidzidzi kwa chakudya chambiri, glypoglycemic state ingachitike - shuga ya magazi nthawi zambiri amakhala pansi pa 0.05-0.07%. Shuga mumkodzo nthawi zambiri samakhalapo, koma amatha kutsimikizika mu matenda ashuga chifukwa cha kuchedwa kwamkodzo wa mkodzo, womwe umalandilidwa ngakhale insulin isanatenge.

Zizindikiro Zambiri

Ndi mankhwala osokoneza bongo ambiri a insulin m'magazi, zomwe zimakhala ndi shuga zimatsika kwambiri. Ngati chizindikirochi chikutsikira pansi 3.3 mmol / l, amalankhula za kukula kwa hypoglycemia.

Ngati mankhwala osokoneza bongo agwiritsidwa ntchito pogwiritsa ntchito insulin yocheperako, zizindikiro zake zimayamba kuwonekera patangotha ​​mphindi zochepa kuti jekeseni. Ngati kukonzekera insulin kukonzekera (depot-insulin) kwayamba kugwiritsidwa ntchito, ndiye kuti zizindikiro za hypoglycemia zimawonekera pambuyo pake ndikuwonjezeka pang'onopang'ono.

Mankhwala osokoneza bongo a insulini amatha kukayikiridwa pamaso pa zizindikiro zotsatirazi zomwe zimachitika patapita nthawi yovulala pambuyo pake:

• kuchuluka kufooka wamba
• tachycardia
• mutu
• kumva kwamphamvu njala.

Ngati pakadali pano ngati simuchita zinthu zofunikira, wodwalayo ayamba kuwonongeka msanga, ndipo zizindikiro zina zidzalumikizana:

• thukuta lalikulu
• kunjenjemera
• dzanzi la zala
• khungu
• hypersalivation
• ana opukusidwa
• anjala yosalephera
• kuchepa kwa mawonekedwe
• Kulephera kuyenda
• kuda nkhawa, kapena, chopinga,
• kudziwa zolakwika
• clonic-tonic kukomoka.

Chowonetsera chowopsa cha insulin yochulukirapo ndikupanga chipere cha hypoglycemic komwe kumayambitsa moyo.

Mankhwala osokoneza bongo a insulin sangakhale kokha owopsa, komanso osachiritsika. Kukula kwakumapeto kumalumikizidwa ndi chithandizo chamankhwala chamafuta a shuga. Pambuyo pakuyambitsa insulin, ngakhale pa mlingo woyenera, kuchuluka kwa shuga m'magazi kumatsika kwakanthawi. Thupi limayesetsa kulipirira izi powonjezera kaphatikizidwe ka glucagon, corticosteroids ndi adrenaline - mahomoni omwe amalimbikitsa kuchuluka kwa glucose.

Zizindikiro za mapangidwe insulin

• chilala chambiri,
• kunenepa
• mawonekedwe a mkodzo wa acetone,
• kupezeka kwa shuga mkodzo,
• pafupipafupi matenda a ketoacidosis
• akulumpha m'magazi a masana masana,
• hypoglycemia yomwe imachitika nthawi ina masana,
• kusintha kwa matenda ashuga kukhala mawonekedwe owopsa.

Mavuto a kagayidwe kakang'ono kogwiritsa ntchito mankhwala osokoneza bongo omwe amapezeka ndi insulin amachititsa kuti m'mawa kwambiri odwala omwe ali ndi matenda amishuga mellitus hyperglycemia amapezeka, ndipo masana, shuga wamagazi amayamba kuchepa ndipo hypoglycemia imayamba.

Choyamba thandizo la insulin

Ngati mankhwalawa ali ndi insulin yambiri, makamaka yanthawi yochepa, thandizo loyenerera liyenera kuperekedwa nthawi yomweyo. Ndiosavuta kwambiri: wodwalayo ayenera kumwa tiyi wokoma, kudya maswiti, supuni ya supuni kapena shuga. Ngati vuto lakelo silikuyenda bwino mkati mwa mphindi 3-5, chakudya chomwe chimakhala ndi zovuta zam'mimba zimayenera kubwerezedwa.

Popeza bongo la insulini limapangitsa kuchepa kwambiri kwa kuchuluka kwa shuga m'magazi, njira zama glucose (20- 40%) zama glucose zimagwiritsidwa ntchito ngati mankhwala.

Kodi chithandizo chachipatala chikufunika liti?

Ngati vuto la insulin yochulukirapo, chithandizo choyamba chayamba kusintha, palibe chifukwa chachipatala chodzidzimutsa. Komabe, posachedwa, wodwalayo amayenera kukaonana ndi dokotala kuti asinthe mlingo komanso pafupipafupi pokonzekera insulin.

Mu milandu yomwe insulin yochulukirapo imakhala yovuta komanso kudya chakudya chamafuta sichimachotsa wodwala ku matenda a hypoglycemia, ndikofunikira kuyitanitsa gulu la ambulansi.

Chithandizo cha odwala omwe ali ndi mankhwala ambiri a insulin amachitika mu dipatimenti ya endocrinology. Ndi kukula kwa hypoglycemic chikomokere - kuchipinda chothandizira kwambiri komanso chisamaliro chachikulu.

M'chipatala, odwala amafunikira mwachangu kuchuluka kwa shuga m'magazi komanso magawo ena a biochemical. Chithandizo cha mankhwalawa chimayamba ndi kupaka kwamitsempha yama glucose 20-25%. Ngati ndi kotheka, glucagon imayendetsedwa intramuscularly.

Ndi chitukuko cha chikomokere, kukonza matenda opuwala kwamankhwala ofunikira kumachitika.

Mavuto omwe angakhalepo

Kugwiritsa ntchito kwambiri mankhwala a insulin sikuwopseza moyo komanso thanzi, madigiri ofatsa a hypoglycemia samapezeka kawirikawiri mwa odwala onse omwe ali ndi matenda a shuga a mtundu woyamba. Komabe, ngati hypoglycemia imachitika pafupipafupi, ndiye kuti kupangika kwa mankhwala osokoneza bongo a insulin kuyenera kukayikiridwa, omwe angakulitse matendawa.

Kugwiritsa ntchito kwambiri mankhwala a insulin kungayambitse kukula kwamitsempha yayikulu:

• Zizindikiro zoyipa
• matenda edema,
• dementia (kusokonezeka kwa malingaliro m'maganizo ndikupanga matenda a dementia).

Hypoglycemia ndiowopsa makamaka kwa okalamba, komanso kwa iwo omwe ali ndi matenda amtima. Odwala a m'magulu awa, amatha kuthana ndi vuto la stroke, myocardial infarction, ndi retinal hemorrhage.

Kanema wochokera pa YouTube pamutu wankhani:

Maphunziro: Ndinamaliza maphunziro ku Tashkent State Medical Institute ndi digiri ya zamankhwala mu 1991. Mobwerezabwereza anachita maphunziro apamwamba kwambiri.

Zochitika kuntchito: wogonetsa-wausiku wothandizirana ndi mzimayi, wogwirizananso ndi dipatimenti ya hemodialysis.

Chidziwitsocho chimapangidwa ndikupatsidwa chidziwitso chokhacho. Onani dokotala wanu chizindikiro choyamba cha matenda. Kudzipatsa nokha mankhwala kuopsa!

Ku UK, kuli lamulo malinga ndi momwe dokotala wothandizira amatha kukanachita opaleshoni ngati atasuta kapena wonenepa kwambiri. Munthu ayenera kusiya zizolowezi zoipa, kenako, mwina, sangafunikire opareshoni.

Pogwira ntchito, ubongo wathu umagwiritsa ntchito mphamvu zambiri zofanana ndi babu la 10-watt. Chifukwa chake chithunzi cha babu wapamwamba pamutu panu panthawi yomwe chikuwoneka ngati chosangalatsa sichili kutali ndi chowonadi.

Caries ndimatenda ofala kwambiri padziko lonse lapansi omwe ngakhale chimfine sangathe kupikisana nawo.

Chiwindi chanu chikasiya kugwira ntchito, imfa imatha pakatha tsiku limodzi.

Asayansi aku America adayesera mbewa ndipo adati madzi amadzi amalepheretsa kukula kwa atherosulinosis yamitsempha yamagazi. Gulu limodzi la mbewa limamwa madzi am'madzi, ndipo lachiwiri ndi madzi a mavwende. Zotsatira zake, zombo za gulu lachiwiri zinali zopanda ma cholesterol.

Mankhwala odziwika bwino "Viagra" adapangidwa poyambirira pochizira matenda oopsa.

Mimba ya munthu imagwira ntchito yabwino ndi zinthu zakunja komanso popanda chithandizo chamankhwala. Madzi am'mimba amadziwika kuti amasungunula ngakhale ndalama.

Mafupa aanthu ndi olimba kwambiri kuposa konkriti.

Poyesera kuti wodwalayo atuluke, madokotala nthawi zambiri amapita kutali kwambiri. Ndiye, mwachitsanzo, Charles Jensen wina mzaka kuyambira 1954 mpaka 1994. adapulumuka ntchito zopitilira 900 neoplasm.

Anthu omwe amakonda kudya chakudya cham'mawa nthawi zambiri amakhala onenepa kwambiri.

Mwazi wa munthu "umayenda" m'matumbo omwe akukakamizidwa kwambiri, ndipo ngati umphumphu wake waphwanyidwa, amatha kuwombera mpaka 10 metres.

Malinga ndi kafukufuku, azimayi omwe amamwa magalasi angapo a mowa kapena vinyo pamlungu amakhala pachiwopsezo chotenga khansa ya m'mawere.

Asayansi ochokera ku Oxford University adachita kafukufuku wambiri, pomwe adazindikira kuti zamasamba zimatha kuvulaza ubongo wamunthu, chifukwa zimapangitsa kuchepa kwa kuchuluka kwake. Chifukwa chake, asayansi amalimbikitsa kuti asachotsere konse nsomba ndi nyama muzakudya zawo.

Chiwindi ndi chiwalo cholemera kwambiri m'thupi lathu. Kulemera kwake pafupifupi 1.5 kg.

Kutentha kwambiri kwa thupi kudalembedwa ku Willie Jones (USA), yemwe adamulowetsa kuchipatala ndi kutentha kwa 46,5 ° C.

Mafuta a nsomba akhala akudziwika kwazaka zambiri, ndipo munthawi imeneyi zatsimikiziridwa kuti zimathandizira kupewetsa kutupa, kuchepetsa ululu wolumikizana, kukonza sos.

More bongo

Kuchepetsa pang'ono kwa mankhwala a insulin omwe dokotala amafalitsa kumathandizira kuti pakhale matenda osapindulitsa kwambiri a insulin, zotsatira zake zomwe ndi kuchepa kwa shuga komanso kuchuluka kwa mahomoni a steroid m'magazi. Mkhalidwe wa pathological umatchedwa Somoji syndrome. Mawonetsero otsatirawa ali ndi chikhalidwe chake:

• kuchuluka kwa matenda ashuga,
• njala yosalekeza
• kuchuluka kwamikodzo yamkodzo
• kunenepa
• chitukuko cha ketoacidosis (kuchuluka kwa matupi a ketone m'magazi),
• kuchuluka kwa acetone mu mkodzo,
• kudumphadumpha pamasana dzuwa,
• hypoglycemia ikutsikira (kuchepa kwambiri kwa shuga m'magazi).

Kuthandiza ndi bongo wa insulin

Akatswiri akukhulupirira kuti thandizo loyamba kwa wovulalayo liyenera kuyamba atangomaliza kuchuluka kwa insulin.

1. Zizindikiro zoyambirira za bongo zikawonekera, mikate yoyera ya 100-150 g imadyedwa. Chochita chimathandizira kuwonjezera shuga.
2. Ngati vuto lomwe limayambika chifukwa cha insulin yochulukirapo silitha, tikulimbikitsidwa kugwiritsa ntchito zakudya zomwe zili ndi chakudya chambiri. Kudya maswiti, shuga, chokoleti kapena kupanikizana kumathandizira kuti wodwalayo asinthe. Pakakhala palibe kusintha kwa mphindi 10, zinthuzi zimagwiritsidwanso ntchito.
3. Mu hypoglycemia yayikulu, yophatikizika ndi kukomoka komanso kukokana, muyenera kuyimba ambulansi. Madokotala amapereka shuga m'mitsempha. Kubwezeretsa shuga, 50 ml ya 40% yankho imagwiritsidwa ntchito. Ngati chikumbumtima sichibwerera pambuyo pa jekeseni, shuga amaperekedwanso. Ngati ndi kotheka, pangani jakisoni wa glucagon. Ndi chitukuko cha chikomokere, mpweya wabwino wa m'mapapo ndikuwonetsetsa kuti ntchito za ziwalo zamkati zimafunikira.

Insulin zizindikiro ndi zizindikiro

Zotsatira zoyambirira: kufooka, chizungulire, palpitations, miyendo yanjenjemera (kapena kungomva kunjenjemera), thukuta, pallor kapena hyperemia ya nkhope, kupweteka mutu, diplopia. Ngati sanatengepo panthawi yake ngati mlingo wa insulin ndi waukulu kwambiri, vutoli limakulirakulira: kutaya chikumbumtima, kupweteka, chikomokere.

Matenda a insulin. Vuto lolakwika ndi loopsa: kukhazikitsidwa kwa vuto la hypoglycemic kwa odwala matenda ashuga komanso kuwonjezeranso insulin.

Lethal mlingo wa insulin

Mlingo wowopsa wa mahomoni a anthu osiyanasiyana ndi osiyana. Anthu ena odwala matenda ashuga amatha kulekerera mayunitsi 300-500, pomwe ena, mayunitsi 100 amatha kukhala owopsa, kupweteketsa thupi ngakhale kufa. Izi zimachitika chifukwa cha zinthu zosiyanasiyana, chimodzi mwa izo ndi kulemera kwa wodwala.

Pomwe munthu wolemera makilogalamu 60 nthawi zambiri amadzivulaza mayunitsi 60, mulingo wa mahomoni 100 umakhala utafa kale. Kwa odwala matenda ashuga omwe amalemera, mwachitsanzo, makilogalamu 90 (nthawi zambiri amagwiritsa ntchito mayunitsi 90), mulingo woyenera ungakhale wabwinobwino. Ichi ndichifukwa chake ndikofunikira kuti musangoganizira kuchuluka kwa insulini zokha, komanso kuchuluka kwake ndi kulemera kwa odwala matenda ashuga, zaka, kupezeka kapena kusowa kwa zovuta.

Insulin bongo woyamba thandizo

Ndi zotsatira zoyambirira za hypoglycemia, perekani 50-100 g mkate. Ngati mphindi 3-5 zatha zizindikiro za hypoglycemia sizikuchoka kapena zilipobe kuyambira pachiyambi, perekani supuni zina zitatu za shuga wamafuta (kapena maswiti). Ngati vutoli silikupita, pambuyo pa mphindi 3-5 chakudya chamagulu owonjezera chizikhala chobwereza mpaka zonse zithe.

Mu kwambiri hypoglycemia (kupweteka, kusazindikira) - kukhazikitsidwa kwa mitsempha ya 50 ml ya glucose 40%. Ngati wodwala sakudutsa Mphindi 10 wodwala, bwerezaninso kulowetsedwa kwa shuga. Ngati sikutheka kubaya shuga m'mitsempha, jekeseni mosamala ndi 500 ml ya glucose 5%, enema ya 10% shuga - 150-200 ml, jekeseni wokhudzana ndi adrenaline (1: 1000) - 1 ml. Wodwala akayambanso kudziwa, mupatseni 50-100 g shuga ndi 100 g mkate.

Zotsatira za kuchuluka kwa insulin

Insulin ndiye mahomoni ofunika kwambiri kapamba ndipo amagwiritsidwa ntchito pochiza matenda ashuga. Mlingo wa insulin ayenera kukhala munthu payekha, kutengera kuopsa kwa matenda ashuga. Kusankha kwa mulingo woyenera wa insulin kumapangidwa motsogozedwa ndi shuga m'magazi ndi mkodzo.

Chofunikira! Mu milandu ya insulin yochuluka, kuchepa kwambiri kwa shuga m'magazi kungachitike - hypoglycemic syndrome (hypoglycemic coma). Mlingo wa kukula kwa chikhalidwe cha hypoglycemic zimatengera insulin yomwe imagwiritsidwa ntchito.

Ngati insulini wamba (yogwira ntchito mwachangu) imagwiritsidwa ntchito, ndiye kuti izi zimachitika mwachangu, munthawi yochepa. Muzochitika pamene kukonzekera kwa insulin ndi nthawi yayitali (ntchito) yayitali - ma depol-insulins, ndiye kuti kumayambika kwa chikomokere kumayamba pang'onopang'ono.

Zizindikiro zazikuluzikulu za kuchuluka kwa insulin zimadziwika ndi zovuta zotsatirazi:

• kufooka kwa minofu, kutopa,
• njala, kusokera kopanda zambiri,
• kugontha, dzanzi la zala, kunjenjemera, malalanje, ana opukusika,
• Maso owoneka bwino, kupweteka mutu, kuyang'ana pafupipafupi, kutafuna,
• kuchepa mphamvu kwa chikumbumtima, kuponderezana kapena kukwiya, zochita zosakhudzidwa, kukhudzika kwamatenda kapena clonic ndipo, pamapeto pake, kukomoka.

Kodi mankhwala a insulin okwanira amatha?

Matenda osokoneza bongo a insulin atheka, ndipo amatchedwa Somoji syndrome. Kuchulukana kwakanthawi kokwanira kwa mahomoni mu mankhwala a shuga kumayambitsa matenda osachiritsika, limodzi ndi kupanga mahomoni omwe amaletsa kuchepa kwa shuga m'magazi. Tikulankhula za adrenaline, corticosteroids ndi glucagon.

Zizindikiro za matenda osokoneza bongo odwala matenda ashuga ayenera kuganiziridwa:

• matenda adakula.
• kulakalaka
• kuchuluka kwa kulemera ndi shuga mu mkodzo,
• chizolowezi cha ketoacidosis (matenda opatsa mphamvu kagayidwe kachakudya),
• acetonuria - mawonekedwe a mkodzo wa acetone.

Chithunzi cha chipatala chimathandizidwa ndi kusinthasintha kwakuthwa kwa zizindikiro za shuga mkati mwa maola 24, nthawi zambiri kuposa momwe zimakhalira, kuwonjezeka kwa chizindikiro cha shuga chamagazi kumadziwika. Kuphatikiza apo, Zizindikiro zimayanjana ndi kulimbana kosalekeza kwa hypoglycemia komwe kumachitika kangapo masana.

Thandizo loyamba ndi thandizo lachipatala

Zachidziwikire, ngati mungakwanitse kuchuluka kwa insulini, chithandizo chofunikira ndikofunikira. Kupitilira apo, othandizira odwala matenda ashuga angathe kuthandizika kwambiri. Thandizo loyamba la kuchuluka kwa insulini kumayamba ndikuwunika kuchuluka kwa shuga - izi zikuthandizira odwala matenda ashuga kuti awonetsetse kuti zoyipa zaumoyo zimatsimikizika molondola. Kuti muchite izi, ndikokwanira kuyeza kuchuluka kwa shuga m'magazi pogwiritsa ntchito glucometer.

Pambuyo pa izi, mutha kuyamba kupereka thandizo loyamba, lomwe limakhala ndi kuchuluka kwa shuga m'magazi. Pazifukwa zomwe zimaperekedwa, wodwala matenda ashuga adzafunika kugwiritsa ntchito china chokoma mwachitsanzo, chokoleti, maswiti kapena mpukutu, tiyi wokoma. Komanso, wodwalayo akulimbikitsidwa kupaka njira yothetsera shuga m'mitsempha - kuchuluka kwa mankhwalawa kumazindikirika mogwirizana ndi chikhalidwe cha odwala matenda ashuga.

Pofuna kuwonjezera kuchuluka kwa shuga m'magazi, ndikofunikira kuti musagwiritse ntchito mafuta ochulukirapo. Kuchuluka kwa shuga kwa munthu wokhala ndi thanzi labwinobwino kungathe kusungidwa mu glycogen (pambuyo pake amagwiritsidwa ntchito posunga mphamvu). Kwa wodwala matenda ashuga, madongosolo oterowo ndi owopsa pakuthothoka kwa minofu ya zomanga, komanso kufinya thupi lonse.

Mutapereka njira zomwe zaperekedwa, muyenera kulumikizana ndi katswiri. Ndi mtundu wodwala wa shuga omwe amadalira insulin, kuyezetsa shuga kumabwerezedwa, mwina kuchipatala. Kutengera ndi zovuta zomwe zachitika, chithandizo chitha kukhala chosiyana kwambiri, mpaka moyo wonse.

Popeza kuopsa koopsa, ndikofunikira kudziwa momwe angaperekere insulin kuti mupewe zovuta.

1. Wodwalayo ayenera kutsatira mosamalitsa malangizo a endocrinologist ndikugwiritsa ntchito jakisoni panthawi yokhayo, ndiye kuti ndiola.
2. Nthawi zambiri, odwala matenda ashuga amadzibweretsera tokha, zomwe zimakhala zowongoka. Pachifukwa ichi, ma syringes apadera amagwiritsidwa ntchito, zomwe sizitanthauza kuti gawo lina la mahomoni mu syringe.
3. Anthu odwala matenda ashuga amangofunika kuyimba pa sikelo yomwe ikufunika, yomwe ikuwonetsedwa m'magawo. Kubayirira kwa gawo la mahomoni kumachitika musanadye chakudya, zonse zimadalira malangizo a endocrinologist.

Malamulo apakati pobweretsa insulin ndi awa: kuchuluka kwa insulin komwe kumatengedwa mu syringe, malo omwe amapangira jakisoni wa singano amathandizidwa ndi mowa. Pambuyo pa jakisoni, osavomerezeka kuti muchotsere singano m'thupi, ndikofunikira kudikirira masekondi 10 - mpaka gawo la mahomoni litalowa bwino.

Mimba imangokhala gawo limodzi la thupi lomwe silingatengeke mwadzidzidzi kuchita zolimbitsa thupi, chifukwa chake, jakisoni wa gawo la mahomoni amachitika chimodzimodzi m'malo omwe akuwonetsedwa. Ngati gawo la mahomoni latulutsidwa mkati mwa minyewa ya miyendo, ndiye kuti kuchuluka kwa mayimidwe kumakhala kotsika kwambiri, motero Chifukwa chake njira iyi ndi yosayenera. Kutsatira malangizo onse omwe atchulidwa kale ndi malingaliro a endocrinologist kumachepetsa mwayi wokhala ndi insulin yambiri.

Mankhwala osokoneza bongo opanga antidiabetes

Maantantitis antidiabetic othandizira ndi zinthu zomwe zimachepetsa shuga m'magazi ndipo zimagwiritsidwa ntchito limodzi kapena m'malo mwa insulini pochiza matenda osokoneza bongo.

Zina mwa izo (makamaka sulfonylurea zotumphukira - butamide, chlorocyclamide, chlorpropamide, etc.) zimatha kuyambitsa mikhalidwe yayikulu ya hypoglycemic. Mosiyana ndi insulin, hypoglycemia yoyambitsidwa ndi mankhwalawa imadziwika ndi njira yosinthira. Amakula pang'onopang'ono komanso mopupuluma. Komabe, nthawi yake imatha kukhala maola angapo mpaka masiku angapo.

Chithandizo cha hypoglycemia sichimasiyana ndi insulin. Komabe, potengera chikhalidwe cha hypoglycemia chofunikira, kuti chilithetse, ndikofunikira kupaka shuga tsiku lililonse motsogozedwa ndi zomwe zimachitika. Milandu yayikulu kwambiri ya hypoglycemia, hydrocortisone imawonjezeranso - 0,2-0.25 g patsiku.

Mankhwala oterowo ayenera kuikidwa mosamala kwambiri pochiza matenda ashuga odwala omwe ali ndi impso ndi chiwindi.

Kodi ndizotheka kufa ndi mankhwala osokoneza bongo ambiri a insulin

Masiku ano, chithandizo chokhacho cha mtundu woyamba wa shuga komanso momwe mungachigwiritsire ntchito polimbana ndi jakisoni wa insulin. Kamodzi m'magazi, insulini imatsitsa shuga mu izo, zomwe zimapangitsa wodwalayo kumva bwino.

Koma kupitirira muyeso wa insulini kungayambitse zotsatira zina, monga mankhwala osokoneza bongo a insulin, omwe amakhala ndi vuto lofunika kwambiri kwa odwala matenda ashuga - hypoglycemic coma.

Kodi mlingo wa insulin umasankhidwa bwanji?

Kwa odwala matenda ashuga aliyense, kuchuluka kwa insulini kumawerengeredwa payekhapayekha, odwala matenda ashuga amaphunzitsidwa kusintha mlingo kutengera mkhalidwe waumoyo kuti kuchuluka kwa insulin sikuchitika.

Kuchuluka kwa mahomoni omwe amadwala matenda ashuga amayenera kuperekera zimatengera zinthu zingapo payokha, zomwe zimadziwika:

• M'badwo
• Kutalika kwa matendawo,
• Kulemera kwa thupi
• Zochita za tsiku ndi tsiku
• Zakudya
• Zochita zolimbitsa thupi
• Zotsatira za kuyesedwa kwa magazi tsiku ndi tsiku.

Ngakhale kuti wodwala aliyense mankhwala omwe akulimbikitsidwa amasiyana, amawerengedwa malinga ndi algorithm imodzi:

• Pa magawo oyamba a matendawa (pamene thupi lokha likhoza kupanga insulini), magawo a 0.5 a insulini amapatsidwa kilogalamu iliyonse ya kulemera.
• Ngati thupi silingathenso kudziimira payokha, gawo limodzi la mahoni kwa kilogalamu iliyonse ya kulemera kwa thupi limayikidwa.

Nthawi zina matendawa amasinthidwa, mwachitsanzo, ngati wodwalayo adachulukitsa kuchuluka kwa chakudya chambiri chakudya chimodzi, kapena kugwira chimfine, chomwe chimapangitsa kutentha kwa thupi lake.

Koma chachikulu chomwe chimapangitsa kuchuluka kwa insulini kuyenera kubayidwa ndi chizindikiro cha shuga m'magazi, ndichifukwa chake odwala matenda ashuga ayenera kukhala ndi mita yamagazi a nyumba yomwe ndi yosavuta kugwiritsa ntchito ndipo imapereka zotsatira m'mphindi zochepa.

Mlingo wosankhidwa bwino wa insulin, ngati uchuluka kuposa zomwe thupi limafunikira, umakhala ndi zotsatirapo monga kuchuluka kwa insulin.

Hypoglycemic chikomokomo: Zizindikiro ndi magawo

Monga tawonera kale, hypoglycemic coma ndi chifukwa cha kuchuluka kwa insulin. Chithunzi cha chipatala cha nkhaniyi chimagawidwa m'magawo anayi:

1. Pa gawo loyamba, hypoxia ya minyewa ya ubongo imachitika, yomwe imayendera limodzi ndi zomwe tafotokozazi.
2. Pa gawo lachiwiri la zomwe tafotokozazi, gawo la ubongo la hypothalamic-pituitary. Nthawi yomweyo, wolakwiridwayo amatuluka kwambiri, amatha kuchita mosadziletsa komanso mwamisala.
3. Gawo lachitatu, ophunzira amadwala kwambiri, minyewa yamthupi imayamba, yomwe ili yofanana ndi khunyu. Pakadali pano, ma Midbrain amakhudzidwa.
4. Gawo lachinayi ndilofunikira. Tachycardia imayamba, ngati simuchita zinthu, ndiye kuti wodwalayo amakhala ndi matenda otupa a ubongo.

Tsoka ilo, mavuto a kukomoka kwa hypoglycemic sangalephereke. Ngakhale chithandizo choyambirira chikaperekedwa kwa wovutikayo, amadzadalira kwambiri jakisoni wa mahomoni.

Kodi zikuwoneka bwanji? Mwachitsanzo, nthawi zina wodwala matenda ashuga sangapange jakisoni panthawi yake, ndipo zizindikiro za mahomoni omaliza zimawonekera pambuyo pake patatha maola awiri ndi atatu. Mwa odwala matenda ashuga omwe adakumana ndi chikomokere, matendawa amawonekera pakatha mphindi 60.

Wathanzi insulin poyizoni

Poizoni wa insulin amayamba chifukwa chakuti pazifukwa zina, munthu amene alibe matenda a shuga amalandira mlingo wa insulin. Milandu ngati imeneyi ndiyosowa, ndipo imadza mwina chifukwa chakuyambitsa kwa mahomoni m'thupi, kapena chifukwa chosasamala madokotala.

Kwa munthu wathanzi, insulini ndi poizoni wakachilengedwe yemwe amachepetsa kwambiri shuga m'magazi. Kuchuluka kwa insulin m'thupi la munthu wathanzi kumawonetsedwa ndi zizindikiro monga:

• Kuthamanga kwa magazi
• Arrhasmia
• Mutu
• Khalidwe lokhumudwitsa
• Mantha opanda pake
• Njala
• Kugwirizana kwamiseche,
• Kufooka minofu.

Pankhani ya poizoni wa insulin, muyenera kudya nthawi yomweyo mankhwala omwe mumakhala chakudya chochuluka, chithandizo chinanso chikuchitika moyang'aniridwa ndi madokotala.

Langizo: Matenda a shuga ndi matenda omwe amatha kuthana ndi kupangitsa chizolowezachi. Zachidziwikire, ngati atazindikira matendawa, munthu amasintha zomwe amachita tsiku ndi tsiku, ndikusintha kwambiri matenda ake, koma, pakapita nthawi, zimakhalanso zochita zofananira monga kupumira. Ndi matenda a shuga, mutha kukhala moyo wangwiro ngati mukuyang'anitsitsa thanzi lanu ndipo musapitirire Mlingo wa insulin.

Mankhwala osokoneza bongo a insulin

Insulin ndi timadzi timene timayendetsa kagayidwe kazakudya m'thupi la munthu ndipo amapangidwa ndi ma cell a pancreatic Langerhans. Ndi iyo, minofu imapanga glucose, chinthu chomwe chimatipatsa mphamvu mthupi.

Mtundu wa I I shuga mellitus (wodalira insulini), insulini yamkati ya pancreatic siipangidwe, chifukwa chake ndikofunikira kuyiyendetsa kuchokera kunja. Kukonzekera kwa insulin kumakhala ndi mahomoni opanga. Jakisoni wawo wokhazikika ndiye msana wa kukonza makhwala a mtundu woyamba wa shuga.

Insulin imakhalanso ndi anabolic, motero imagwiritsidwanso ntchito pochiza matenda ena, imagwiritsidwanso ntchito ndi omanga thupi kuwonjezera minofu.

Zowopsa za insulin ndi zotumphukira zake: protamine-zinc-insulin ndi triprotamine-zinc-insulin

Kuledzera kwambiri kwa insulin kumatha kuchitika mopitirira muyeso wa mankhwalawa ndipo kumawonetsedwa mu chikomokere cha hypoglycemic, pomwe nthawi zambiri kupweteka kumachitika.

Chofunikira! Kuchepa kwakukulu kwa shuga m'magazi kumachitika patatha maola 2-4 pambuyo pobayira jakisoni wa mankhwala ochiritsira (ndikupereka mankhwala okhazikika, hypoglycemia sichitchulidwa kwenikweni, koma imatenga mpaka maola 8).

Zizindikiro zochokera mkati mwa dongosolo lamanjenje ndizogwirizana kwambiri ndi kuchuluka kwa shuga mumagazi a cerebrospinal kuposa m'magazi, motero kuopsa kwa zizindikirozi sikugwirizana kwenikweni ndi kuchuluka kwa hypoglycemia.

Kuthekera kwa poizoni wa mankhwala kumadalira makamaka kusinthasintha kwakukulu kwa Mlingo wa kusinthasintha kwakukulu pakubwezeretsanso insulin. Kusintha koteroko kumachitika osati mwa anthu osiyanasiyana, komanso kwa odwala omwewo omwe ali ndi matenda ashuga.

Zotsogola zam'magawo a hypoglycemic ndi kufooka, kunjenjemera (kapena "kumanjenjemera") m'manja, njala, malovu, kutuluka thukuta, kumva kutentha (pallor kapena, kutembenuka kwamaso chifukwa cha kuphwanya kwa vasomotor innervation), chizungulire komanso (nthawi zina) mutu .

Ndi kuwonjezeka kwa hypoglycemia, vuto lalikulu limatha kukhala ndikutha kukumbukira komanso kukhumudwa. Popeza wodwala wodwala matenda ashuga amatha kupweteka komanso kukomoka chifukwa cha jakisoni wa insulin, ndikofunikira kudziwa kusiyana pakati pawo:

• Matenda a matenda ashuga amakula pang'onopang'ono patapita nthawi yayitali. Pomwe pamakhala mpweya wambiri, wopanda phokoso, mpweya wotuluka uli ndi fungo la acetone, khungu limakhala louma, kamvekedwe ka minofu kachepa kwambiri, kugunda kwake kumachitika.
• hypoglycemic coma yomwe imayamba chifukwa cha insulin imayamba msanga komanso kuchepa kwa chikumbumtima kumatha kuchitika ngakhale popanda okhazikika omwe atchulidwa pamwambapa, kupuma ndizobwinobwino, palibe fungo la acetone, thukuta limadziwika kuti, kamvekedwe ka minofu sikachepetsedwa, kukokana kumatha kuchitika, kusintha kwa mtima kumakhala kosavomerezeka wodekha).

Kupewa mankhwala osokoneza bongo a insulin

Popewa poyizoni wa insulin, muyenera kuchita izi:

• ngati kuli kotheka, musapange jakisoni usiku ngati wodwalayo sayang'aniridwa ndi akatswiri odziwa ntchito zamankhwala, chifukwa hypoglycemia imatha kuyamba usiku pamene wodwala alibe thandizo (jakisoni wa mankhwala olimba omwe amaperekedwa usiku ndi otetezeka pazifukwa zomwe zanenedwa pamwambapa),
• kuphunzira wodwala ndi zotsogola zam'magazi a hypoglycemic zomwe zitha kuwononga thanzi, komanso kufunikira kokhala ndi chakudya cham'mimba mosavuta (mkate, zopaka, shuga, maswiti).

Kodi kuvulala kwa mankhwala a insulin kwambiri ndi chiyani?

Chithunzi cha chipatala cha mankhwala osokoneza bongo a insulin, monga njira yothandizira mankhwalawa a shuga a insulin, ndi polymorphic. Munthawi iliyonse ya chitukuko cha bongo wa insulin, kuyang'anira wodwalayo pafupipafupi ndikofunikira, komanso kuyesedwa kwa chitukuko cha hypently hypemlycemia.

Kuwopseza mosayembekezeka kwa ulesi ndi kugona komwe kumachitika mutatha kudya chizungulire, komanso kupweteka mutu, ndizodziwonetsera kwambiri za bongo. Nthawi zambiri, Zizindikiro izi ndi zomwe zingasonyeze mavuto azaumoyo.

Ngati bongo wa insulin ikayamba kuwoneka usiku, ndiye kuti pali kuphwanya mtundu wa nthawi ndi kugona, kulota usiku, hyperhidrosis, mutu. Munthawi imeneyi, ngakhale munthu wagona kwa nthawi yayitali, sangathe kugona mokwanira, akumva kupsinjika tsiku lonse.

Ndi bongo wa insulin, kusinthasintha kwa m'maganizo, kukhumudwa, mantha komanso kusakwiya nthawi zambiri kumachitika. Ngati mankhwala osokoneza bongo a insulin amawonekera mwa mwana kapena wachinyamata wazaka zosinthika, ndiye kuti ziwonetserozo zaukali ndi zovuta za kudya siziperekedwa.

Monga lamulo, bongo wa insulin yochulukirapo imadziwika kwambiri ndi ana, achinyamata komanso achinyamata omwe amagwiritsa ntchito Mlingo waukulu wa insulin kuti akhazikitse mkhalidwe wawo. Mothandizidwa ndi izi, ana amayamba kuwonetsa kuchepa, pali kukulitsa kwa chiwindi kukula kwake.

Chawonetsero chofunikira kwambiri cha mankhwala osokoneza bongo a insulin ndi kuchuluka kwa wodwala, ngakhale kuwonongeka kwa matenda a shuga, chifukwa choti odwala amachepetsa thupi pafupipafupi.

Mankhwala osokoneza bongo a insulin - mawonekedwe akulu a matenda osachiritsika

• kusakhazikika kwenikweni kwa matenda a shuga omwe amadalira insulini komanso kusinthasintha kwakuthwa kwa index ya glycemic tsiku lonse,
• okhazikika komanso obwera chifukwa cha hypoglycemia,
• kunenepa kwambiri, ngakhale kuti odwala amapezeka ndi matenda a shuga kuwonda,
• ndi kuwonjezeka kwa Mlingo wa insulin, kuwonongeka kwa thanzi la wodwalayo, kuphatikizika kwa maphunziro a matenda ashuga, kubwezeretsedwa kumatheka pokhapokha kuchepa kwakukulu kwa mlingo wa insulin.

Mankhwala osokoneza bongo kwambiri a insulin ayenera kusiyanitsidwa ndi dziko lomwe limatchedwa "m'mawa kutcha", pamene glycemia imakwera chifukwa chakuti m'mawa kwambiri miyendo ya tsiku ndi tsiku yobisika ya mahomoni monga adrenaline, cortisol, mahomoni amakula komanso kusintha kwa glucagon.

Malangizo! Mbali iyi ya thupi la odwala matenda ashuga imatha kuoneka mwa anthu athanzi, koma ndimatenda a shuga omwe amadalira matenda a shuga amayamba kutchulidwa.

Kuwonjezeka kwa kuchuluka kwa glycemic panthawi yopanga matenda a shuga kungayambike, komabe, osati ndi boma la "m'mawa kutacha", komanso kukhala chifukwa cha hypoglycemia usiku. Kuganiza kumeneku kungatsimikiziridwe kapena kutsimikizidwanso mwakuwona kuchuluka kwa shuga m'magazi pakati pa 2 ndi 3 maw m'mawa.

Insulin Overdose - Chithandizo

Chithandizo cha mankhwala osokoneza bongo a insulini ndikuwunika mlingo wa insulin womwe umaperekedwa kwa wodwala. Ngati mukukayikira kuchuluka kwa insulin, wodwalayo amachepetsedwa ndi pafupifupi 15-20%. Mkhalidwe wa wodwala umayang'aniridwa mosamala.

Kuchepetsa mulingo wa insulin kungachitike m'njira ziwiri - mwachangu komanso pang'onopang'ono. Ndi kuchepa msanga, mlingo umachepetsedwa pazofunikira pafupifupi milungu iwiri, ndikuchepera - m'miyezi iwiri. Ndiosavuta komanso mwachangu kukwaniritsa kuchepetsedwa kwa mankhwala a insulin mukamagwiritsa ntchito mankhwala olimbitsa.