Hypolipidemic mankhwala Tricor 145 mg: analogues, mtengo ndi kuwunika kwa wodwala

Tricor 145 ndi wothandizira pakamwa wa hypolipidemic womwe umagwiritsidwa ntchito pazachipatala kuti muchepetse mafuta ambiri a cholesterol ndi triglycerides. Kuwonongeka kwa hypercholesterolemia ndikofunikira kuti muchepetse chiopsezo cha atherosulinosis komanso kupewa mapangidwe a atherosranceotic mapoma pamakoma a chotengera. Mankhwala amachepetsa chiwopsezo cha kuundana kwa magazi chifukwa chokakamira kuphatikizika kwa maselo amwazi.

Kutulutsa mafomu ndi kapangidwe kake

Mankhwalawa amapezeka m'miyala yoyera pakamwa. Gawo lililonse la mankhwalawa lili ndi 145 mg yogwira mankhwala - fenofibrate nanoparticles. Zotsatirazi zimagwiritsidwa ntchito kuti chiwonjezere liwiro komanso kufalikira kwathunthu molumikizana ndi chinthu chogwira:

• crospovidone
• hypopellose,
• cellcrystalline mapadi,
• mafuta a lauryl sodium komanso profusate wa sodium,
• shuga mkaka, sucrose,
• colloidal dehydrogenated silicon dioxide,
• magnesium wakuba.

Tricor 145 imapezeka m'magome oyera a pakamwa pakamwa ndipo ili ndi 145 mg yogwira - fenofibrate nanoparticles.

Mapiritsiwo amakutidwa ndi nembanemba wa filimu, yemwe amasungunuka pansi pa zochita zamatumbo. Kanemayo amakhala ndi mowa wa polyvinyl, titanium dioxide, talc, soya lecithin, chingamu cha xanthan.

Zotsatira za pharmacological

Mankhwala a hypoglycemic ndi a gulu la fibrate. Makina a zochita za pawiri yogwira amatengera kutseguka kwa alpha receptors. Chifukwa chakuwonjezera ntchito yawo yogwira ntchito, lipolysis ndi excretion ya lipoproteins yokhala ndi ma triglycerides ambiri imalimbikitsidwa.

Fenofibrate imapangidwa kuchokera ku fiber acid, yomwe imatha kukhudza mulidi wa lipids m'thupi la munthu chifukwa cha kuyambitsa kwa alpha receptors. Chifukwa chakuchita bwino kwa mankhwalawa, kuchuluka kwa lipoproteins yotsika kwambiri (LDL) kumachepa ndipo kachigawo kakakulu kachulukidwe (HDL) kachuluka. Mayeso oyesera adawonetsa kuchepa kwa cholesterol yathunthu ndi 25%, triglycerides ndi 45-55% komanso kuwonjezeka kwa ndende ya HDL ndi 10-30%.

Munthawi yamankhwala othandizira, chiwopsezo cha kusintha kwa ma atherosselotic mu vasotor endothelium chimachepetsedwa ndipo mwayi wopanga cholesterol plaque pamakoma amitsempha amachepa. Ndi kugwiritsa ntchito mankhwalawa kwa nthawi yayitali, kuchuluka kwa zothandizira kumachepa. Pamaso pa hyperuricemia, odwala amalandila mwayi wina wochepetsedwa 25% mu uric acid.

Tricor 145 - mankhwala a hypoglycemic ndi a gulu la mafupa.

Pharmacokinetics

Akalowa m'matumbo, mapiritsiwa amawongolera ndi ma protein kuti apange fenofibroic acid. Mankhwalawa amasiyana m'magazi, pomwe amafikira pazofunikira zambiri mkati mwa maola 2-4. Yogwira kagayidwe kachakudya imalowa mu khoma lamatumbo momwe muli nanoparticles, kotero kugwiritsidwa ntchito kofanana ndi chakudya sikukukhudza kuchuluka kwa mayamwa komanso kukwaniritsidwa kwa bioavailability. M'mitsempha yamagazi, 99% yogwira fenofibroic acid imapanga zovuta ndi plasma albin.

Zinthu zamankhwala sizisintha m'maselo a chiwindi. Hafu ya moyo wa metabolite yogwira ndi maola 20. Mankhwalawa amasiya thupi ndi mkodzo mkati mwa sabata limodzi.

Zizindikiro zogwiritsidwa ntchito

Mankhwalawa amagwiritsidwa ntchito kukweza cholesterol ndi triglycerides kapena dyslipidemia wochepetsedwa ndi chithandizo chamankhwala, kuwonjezera zolimbitsa thupi ndi njira zina zosagwiritsa ntchito mankhwalawa polimbana ndi kunenepa kwambiri. Makamaka pamaso pa ochepa matenda oopsa ndi zizolowezi zoipa.

Muzochita zamankhwala, mankhwalawa angagwiritsidwe ntchito kuthetsa metabolic syndrome ndi hyperlipoproteinemia pokhapokha kuchuluka kwa lipoproteins kulimbikira ngati chithandizo cha matenda oyamba a pathological sichitha.

Tricor 145 imagwiritsidwa ntchito kukweza cholesterol ndi triglycerides kapena dyslipidemia wosavomerezeka ndi zakudya.

Contraindication

Mankhwala okhazikika motsutsana milandu:

• kwambiri galactosemia, lactase ndi kuchepa kwa fructose, galactose-glucose syndrome, sucrose-isomaltase malabsorption,
• kukhalapo kwa chidwi chochulukirapo pakuwala, kuzinthu zopangika za Tricor,
• chiwindi ndi matenda a impso,
• Phototoxicity pa mankhwala ndi Ketoprofen, michere,
• Matenda a pathological mu ndulu,
• anaphylactic zochita za mtedza, soya ndi batala.

Ndi chisamaliro

Ndikofunikira kuwunika momwe wodwala alili pokhapokha pomayambitsa matenda omwe ali m'munsiwa:

• ofatsa pang'ono komanso aimpso kuchepa,
• uchidakwa wambiri,
• ukalamba
• mtundu wamtundu wamatenda a minofu,
• kufanana mankhwala ndi yosalunjika anticoagulants ndi blockers a HMG-CoA reductase.

M'pofunika kuyang'anira wodwala matenda ake akaperekedwa motsutsana ndi maziko a zakumwa zoledzeretsa.

Momwe mungatenge Tricor 145 mg

Mapiritsi ayenera kumwedwa pakamwa popanda kutafuna. Kuwonongeka kwa membrane wa filimu kungayambitse kuchepa kwa kusintha kwa fenofibrate kukhala fenofibroic acid yogwira. Mankhwalawa amatha kumwa tsiku lonse, mosasamala chakudya. Odwala achikulire ayenera kumwa piritsi limodzi la 145 mg kamodzi patsiku.

Kutsitsa kwa lipid kumatha kugwira ntchito pakudya komwe kumapitilizidwa komanso muzochitika zolimbitsa thupi. Odwala omwe adathandizidwa ndi 160 mg ya mankhwalawa safuna kuchepetsedwa pang'onopang'ono kwa mlingo mpaka 145 mg.

Matumbo

Matenda a dongosolo logaya chakudya amasonyezedwa mawonekedwe a ululu wa epigastric, kusanza, kapangidwe ka mpweya ndi matumbo olimbitsa. Pancreatitis ikhoza kuchitika.

Odwala omwe ali ndi matenda osokoneza bongo sasowa sikutanthauza kusintha kwa mankhwala a insulini ndi hypoglycemic.

Pa khungu ndi mafuta onunkhira

The zimachitika khungu lawo siligwirizana, yodziwika ndi mawonekedwe a zidzolo, urticaria, kuyabwa kwambiri. Nthawi zina, chidwi chakuwala chikuwonjezereka pakhungu, munthu amayamba kusiya tsitsi. Photosensitivity ikhoza kukhala limodzi ndi erythema, kupezeka kwa matuza.

Pa mbali ya chiwindi ndi biliary thirakiti

Nthawi zambiri, ntchito zimawonjezeka ndipo kuchuluka kwa hepatic aminotransferase mu seramu yamagazi kumawonjezeka. Nthawi zina, cholelithiasis imayamba, mwina kutupa kwa chiwindi. Ngati zizindikiro za hepatitis zikuwoneka ngati jaundice ndi kuyabwa, ndikulimbikitsidwa kuyezetsa matenda a labotale kuti mutsimikizire ngati ali ndi matendawa. Mukalandira zotsatira zabwino, kugwiritsa ntchito fenofibrate kutha.

Malangizo apadera

Musanayambe mankhwala osokoneza bongo, ndikofunikira kuti muchepetse zovuta zomwe zimayambitsa yachiwiri ya hypercholesterolemia, yomwe imatha kuchitika motsutsana ndi maziko a matenda a shuga 2, uchidakwa. Kuchita bwino kwa mankhwalawa kumalimbikitsidwa kuti kuwunikidwe ndi ma laborator chizindikiro a kuchuluka kwa mafuta a seramu. Popeza lipid-kutsitsa kanthu mkati mwa miyezi itatu, ndikofunikira kufunsa dokotala wanu pakuthana ndi mankhwalawa.

Nthawi zina, motsutsana ndi maziko a mankhwalawa, kuyambika kwa njira yotupa mu kapamba ndikotheka.

Nthawi zina, motsutsana ndi maziko a mankhwalawa, kuyambika kwa njira yotupa mu kapamba ndikotheka. Zomwe zimayambitsa pancreatitis zimatha kukhala miyala komanso kuperewera kwa ndulu mu ndulu, kusakwanira kochiritsa kotsutsana ndi maziko a hypertriglyceridemia.

Zokhudza mphamvu pakuwongolera njira

Mankhwala si doping kapena psychotropic, sizikuwawononga ntchito yapakati ndi zotumphukira mantha dongosolo. Chifukwa chake, mukamalandira chithandizo ndi Triicor, amaloledwa kuwongolera magwiridwe antchito ndi galimoto, yomwe imafunika kuthamangitsidwa ndikuwonetsetsa mwachangu.

Kupangira TRICOR 145 mg kwa ana

Oral hypolipidemic woletsedwa amaletsa kufika zaka 18 chifukwa chosowa chidziwitso cha mphamvu ya fenofibroic acid pakukweza kwa thupi la munthu pasukulu yasukulu komanso paunyamata.

Bongo

Wothandizira wotsutsa alibe. Izi ndichifukwa chakusowa kwa milandu yambiri. Pogwiritsa ntchito mapiritsi amodzi kamodzi, pali njira zambiri zowonjezera zovuta zowonjezera zomwe zimachitika. Ngati mukukayikira kuti pali mankhwala osokoneza bongo, muyenera kupita kuchipatala. Mankhwalawa sachotsedwa ndi hemodialysis.

Ndi zoletsedwa kumwa mowa panthawi yamankhwala ndi Tricor.

Kuphatikiza kophatikizidwa

Fenofibroic acid imawonjezera mphamvu yothandizira anticoagulants pakamwa. Chifukwa cha kuphatikiza uku, kutulutsa magazi mkati. Zotsatira zoyipa izi zimachitika chifukwa chakumasulidwa kwa anticoagulant kuchokera kumalo omanga mapuloteni a plasma.

Kumayambiriro kwa mankhwala osokoneza bongo ndi fenofibrate, tikulimbikitsidwa kufunsa dokotala zakufunika kochepetsera Mlingo wa anticoagulants wa tsiku ndi tsiku. Kusankhidwa kwa mtundu wotsatira kwa mankhwalawa kumachitika molingana ndi mtundu wa INR.

Pogwiritsa ntchito mapiritsi amodzi kamodzi, pali njira zambiri zowonjezera zovuta zowonjezera zomwe zimachitika.

Kuphatikiza komwe kumafunikira kusamala

Ndikulimbikitsidwa kuti nthawi zonse muziyang'anira magwiridwe antchito pomwe mupanga Tricor ndi cyclosporine kapena maantibayotiki. Akaphatikizidwa, pamakhala chiwopsezo cha kulephera kwambiri kwa impso. Ndikusintha kwamphamvu magawo a labotale, muyenera kusiya kutenga Tricor.

Mankhwalawa akhoza kutha ndi amodzi mwa awa:

Mapiritsi a Tricor: kuchokera ku chiyani ndi mtengo wa mankhwalawo

Tricor wa mankhwala amaikidwa pokhapokha:

• Hypercholesterolemia yokhala ndi chakudya chamagulu,
• hypertriglyceridemia ndi zakudya zomwe sizothandiza,
• hyperlipoproteinemia yachiwiri.

Mtengo wa kulongedza mapiritsi a Tricor 145 mg ndi pafupifupi 800-900 rubles.

Njira yogwiritsira ntchito

Tricor ya mankhwalawa imatengedwa kokha mkati osafuna kutafuna, pakumwa zakumwa zambiri.

Kudya kwa mankhwalawa sikudalira nthawi yake motero kungagwiritsidwe ntchito nthawi iliyonse ya tsiku, komanso mosasamala kanthu ndi chakudya. Tengani ma milligram 160.

Akuluakulu amayikidwa piritsi limodzi maola 24 aliwonse, mulingo womwewo umaperekedwa kwa anthu ndi okalamba. Kutenga mankhwalawa kwa odwala omwe ali ndi vuto la impso amaloledwa muyezo wochepetsedwa, komabe, izi zitha kuikidwa pambuyo pofunsa dokotala.

Zotsatira zoyipa

Monga mankhwala ena aliwonse, Tricor wa mankhwalawa amakhalanso ndi zovuta zomwe zimawonekera mumachitidwe osiyanasiyana:

• kupweteka pamimba nthawi zambiri kumayendetsedwa ndi mseru komanso kusanza, koma zizindikirozi zimatha kuyang'aniridwa padera,
• kutsegula m'mimba
• matenda a kapamba ndi osowa kwambiri,
• matenda a chiwindi
• myositis
• phatikizani myalgia,
• minofu kukokana ndi kufooka,
• kawirikawiri - mapangidwe a ndulu mu chiwindi,
• chigoba minofu necrosis (chosowa kwambiri)
• venous thromboembolism,
• kuchuluka hemoglobin,
• kuchuluka kwa maselo oyera
• kusowa pogonana
• mutu
• zotupa pakhungu,
• kuyabwa
• urticaria
• alopecia
• kapangidwe ka matuza pakhungu.

Komabe, anthu ambiri amadandaula chifukwa cha mankhwalawa chifukwa cha mseru komanso m'mimba, zomwe zimadziwika kale tsiku loyamba kumwa mankhwalawa.

Ambiri mwa omwe akukumana ndi vutoli amadziwa kuti zovuta zake zimakhala zakanthawi kochepa, ndipo mothandizidwa ndi mankhwalawo mutha kupirira.

Mankhwala a Tricor 145 monga awa:

Mankhwala a Innogem amachepetsa kuchuluka kwa triglycerides, cholesterol, lipoproteins m'magazi. Njira yofunika kwambiri yogwiritsira ntchito mankhwalawa ndi kutsegula kwa lipoprotein lipase.

Mankhwalawa amalembera hyperlipidemia yoyamba. Amagwiritsidwa ntchito muyezo wamba kwa achikulire, makapisozi anayi patsiku, omwe ali ofanana ndi mamiligalamu 1200. M'pofunika kumwa makapisozi atatu Mlingo - m'mawa ndi madzulo 30 mphindi musanadye.

Pogwiritsa ntchito mankhwala Innogem, zotsatira zoyipa zambiri zimawonedwa:

• nseru, nthawi zina limodzi ndi kusanza,
• chisangalalo
• kamwa yowuma
• kudzimbidwa pafupipafupi
• kupweteka m'mimba
• mutu
• kuwonongeka kwamawonekedwe
• khungu limasanza ngati ziwengo,
• kupweteka kwa minofu
• kuchepa magazi
• myalgia
• paresthesia
• hypokalemia
• alopecia
• kusintha kwa magazi.

Mankhwalawa ali ndi ntchito ya fibrinolytic, yomwe imakhudza mfundo yoti ngati imagwiritsika ntchito kwa nthawi yayitali imalimbikitsa kukonzanso kwa fibrin ndikuyambitsa kukonzanso kwa tendon xanthomas.

Njira imeneyi imaphatikizira kuponderezana kwa hypercholesterolemia. Mankhwalawa amatha kuwonjezera mphamvu ya chakudya chomwe chikufuna kuchepetsa cholesterol.

Mankhwalawa amatengedwa pakamwa pokhapokha mamiligalamu 100 kamodzi patsiku, omwe ali ofanana ndi kapisozi, komabe, muyenera kudziwa kuti kugwiritsa ntchito mankhwalawa mosalephera aimpso kuyenera kutsitsidwa mpaka mamiligalamu 100 patsiku.

Pakukonzekera Lipanor, zotsatirazi zoyipa zitha kuonedwa:

• kupweteka mutu pafupipafupi
• chizungulire
• kugona kwambiri
• nseru
• kusanza
• kutsegula m'mimba
• kufooka wamba ndi minofu,
• dziko lokhumudwitsa
• cholestasis
• myalgia
• kusabala
• alopecia
• zotupa pakhungu,
• kuyabwa
• urticaria.

Mankhwalawa ndi othandizira kutsika kwa lipid. Amawerengera hypercholesterolemia ndi hypertriglyceridemia kwa odwala omwe satsatira njira zina zosagwiritsa ntchito mankhwala.

Amagwiritsidwa ntchito kokha mkati, ngakhale zakudya. Kwa akulu ndi ana, mulingo womwewo umaperekedwa kamodzi patsiku osapitirira 10 mg. Mlingo ungathe kuwonjezeka kamodzi sabata iliyonse, koma osapitirira 18 mg pa tsiku.

• nseru
• chisangalalo
• kudzimbidwa
• kutsegula m'mimba
• dyspepsia
• mutu
• asthenia
• kusowa tulo
• myalgia.

Mankhwalawa akuwonetsedwa kuti azigwiritsidwa ntchito kuwonjezera pa zakudya, komanso njira zina zosagwiritsira ntchito mankhwalawa, mwachitsanzo, masewera olimbitsa thupi komanso kuchepa thupi.

Imwani kapisozi imodzi, yomwe ili ndi 250 mg, kamodzi patsiku mukudya. Mankhwala amagwiritsidwa ntchito kwa nthawi yayitali.

Mankhwala Lipofen 200 mg ndi 67 mg

Zotsatira zoyipa zomwe zingagwiritsidwe ntchito pogwiritsa ntchito mankhwalawa:

• kuchuluka kwa hemoglobin,
• Hypersensitivity
• mutu
• kusanza pamodzi ndi kusanza,
• kutsegula m'mimba
• chisangalalo
• jaundice
• zotupa ndi kuyabwa,
• kusowa pogonana.

Makanema okhudzana nawo

Pofuna kuti musagule mankhwala Tricor ndi mapikidwe ake, gwiritsani ntchito kupewa matenda a atherosulinosis:

Tricor ndi mankhwala opangira matenda a hyperlipoproteinemia, hypercholesterolemia. Ili ndi malo ena ambiri, kotero sizingakhale zovuta kusankha analogi ya Tricor Russian kapena yoitanitsa.

• Imakhazikika pamisempha ya shuga kwa nthawi yayitali
• Imabwezeretsa kapangidwe ka insulin

Phunzirani zambiri. Osati mankhwala. ->