Zizindikiro za 8 za mapiritsi a Amoxiclav 2x

tabu. p / wogwidwa. sheath 250 mg + 125 mg vial, No. 15 39.85 UAH.

Amoxicillin 250 mg

Clavulanic acid 125 mg

Zosakaniza zina: cellcrystalline cellulose, croscarmellose sodium.

Nayi UA / 3011/01/01 kuyambira pa 4/07/2005 mpaka pa 4/07/2010

tabu. p / wogwidwa. yokutidwa 500 mg + 125 mg, No. 15

Amoxicillin 500 mg

Clavulanic acid 125 mg

Zosakaniza zina: cellcrystalline cellulose, croscarmellose sodium.

popeza d / p kuyimitsidwa. d / vnutr. pafupifupi. 156.25 mg / 5 ml botolo la 100 ml, No. 1 22.03 UAH.

Amoxicillin 125 mg / 5 ml

Clavulanic acid 31.25 mg / 5 ml

Zosakaniza zina: sodium citrate, sodium benzoate, cellcrystalline cellulose, sodium saccharin, mannitol.

No. P.05.01 / 03091 kuyambira pa 04/19/2006 mpaka pa 04/19/2011

popeza d / p r-d d / pa. pafupifupi. 156.25 mg / 5 ml vial 25 g, d / p 100 ml kuyimitsidwa.

Amoxicillin 125 mg / 5 ml

Clavulanic acid 31.25 mg / 5 ml

Zosakaniza zina: sodium citrate, sodium benzoate, cellcrystalline cellulose, sodium saccharin, mannitol.

No. UA / 3011/03/01 kuyambira pa 04/19/2006 mpaka pa 04/19/2011

popeza d / p yankho la mu / mu. 600 mg fl., No. 5 72.07 UAH.

Amoxicillin 500 mg

Clavulanic acid 100 mg

No. UA / 3011/02/01 kuyambira pa 4/07/2005 mpaka pa 4/07/2010

popeza d / p yankho la mu / mu. 1200 mg fl., Palibe 5 109.97 UAH.

Amoxicillin 1000 mg

Clavulanic acid 200 mg

No. UA / 3011/02/02 kuyambira pa 4/07/2005 mpaka pa 4/07/2010

tabu. p / wogwidwa. 500 mg + 125 mg sheath, No. 10

tabu. p / wogwidwa. 500 mg + 125 mg chipolopolo, No. 14 41.78 UAH.

Amoxicillin 500 mg

Clavulanic acid 125 mg

Nayi UA / 3012/01/01 kuyambira pa 4/07/2005 mpaka pa 4/07/2010

tabu. p / wogwidwa. 875 mg + 125 mg pachimake, No. 10

tabu. p / wogwidwa. 875 mg + 125 mg chipolopolo, No. 14 58.28 UAH.

Amoxicillin 875 mg

Clavulanic acid 125 mg

No. UA / 3012/01/02 kuyambira pa 4/07/2005 mpaka pa 4/07/2010

tabu. kupezeka. 500 mg + 125 mg, No. 10

Amoxicillin 500 mg

Clavulanic acid 125 mg

No. UA / 3011/04/02 kuchokera pa 05.25.2007 mpaka 05.25.2012

tabu. kupezeka. 875 mg + 125 mg, No. 10

Amoxicillin 875 mg

Clavulanic acid 125 mg

Mankhwalawa ali ndi clavulanic acid mu mawonekedwe a mchere wa potaziyamu ndi amoxicillin mu mawonekedwe a trihydrate (mitundu ya Mlingo wothandizira pakamwa) kapena mchere wa sodium (ufa wa jekeseni).

No. UA / 3011/04/01 kuchokera pa 05.25.2007 mpaka 05.25.2012

Mankhwala

Amoxiclav ndi kuphatikiza kwa amoxicillin (anti-spectrum penicillin antiotic) ndi clavulanic acid (a β-lactamase inhibitor omwe amapanga okhazikika, osagwira ntchito mogwirizana ndi iwo ndipo amalepheretsa kuwonongeka kwa amoxicillin). Amoxiclav ali ndi mawonekedwe osiyanasiyana. Mankhwalawa amagwira ntchito motsutsana ndi tizilombo tating'onoting'ono tokhala ndi amoxicillin komanso mabakiteriya omwe sagwirizana nayo, amatulutsa β-lactamases, kuphatikizapo gram-aerobes (Streptococcus pneumonia, Str. Pyogene, Str. Bovis, Staphylococcus aureus, S. epidermidis, Listeria spp. , Enterococcus spp.), Gram-negative aerobes (H. fuluwenza, Moraxella catarrhalis, E. coli, Proteus spp., Klebsiella spp., N. gonorrhoeae, N. meningitidis, Pasteurella multocida) ndi anaerobic (Peptococcus spp. Peptostrept. Peptostrept. Clostridium spp., Bacteroides spp., Actinomyces israelii) mabakiteriya.

Mafuta a pharmacokinetic apamwamba a amoxicillin ndi clavulanic acid ndi ofanana ndipo, akaphatikizidwa, samakhala ndi mphamvu pa pharmacokinetics ya chilichonse mwazinthu. Pambuyo pakulowetsa, zigawo zonse ziwiri za mankhwalawa zimaphatikizidwa bwino, kuchuluka kwakukulu mu seramu yamagazi kumafikiridwa pambuyo pa ola limodzi. Kudya sikumakhudza kuyamwa kwa zinthu zomwe zimagwira. Hafu ya moyo wa amoxicillin ndi mphindi 78, ndipo asidi wa clavulanic ndi mphindi 60-70. Magawo onsewa amalowerera mosavuta m'madzimadzi ambiri amthupi ndi zotupa (mapapu, khutu lakumaso, maxillary sinus secretion, fluid ya pleural and peritoneal, chiberekero. mkaka wa m'mawere.

Pambuyo pa kubayidwa kwa jakisoni wa Amoxiclav mu mlingo wa 1,2 g, kuchuluka kwambiri kwa amoxicillin mu seramu yamagazi ndi 105.4, clavulanic acid - 28,5 mg / L. The kuchuluka pachimake mu madzi am'madzi amawonedwa ola limodzi atatha kuchuluka pazambiri zamagazi seramu. Amoxicillin ndi clavulanic acid amamangiriza mapuloteni a plasma pofika 1720 ndi 22-30%, motero.Amoxicillin amamuchotsa mkodzo makamaka osasinthika, ndipo clavulanic acid amayamba kusintha kagayidwe kachakudya ndipo amawakumba makamaka ndi impso, ndikuwathandizanso pang'ono ndi ndowe komanso mpweya wotha ntchito.

Amoxiclav 2x - zisonyezo zogwiritsidwa ntchito

Matenda am'mapapo komanso ammunsi kupuma komwe kumayambira ndi ma microorganism omwe amathandizira Amoxiclav (kuphatikizapo bronchitis ndi chibayo), pachimake komanso matenda osokoneza bongo otitis, chithupsa cham'mimba, matenda a odontogenic (kuphatikizapo periodontitis), matenda amkodzo thirakiti, matenda a gynecological, ndi chinzonono (kuphatikizidwa chifukwa cha kupindika kwa gonococci kupanga b-lactamase), chancroid, khungu ndi matenda ofewa amtundu (kuphatikizapo matenda a bala), matenda am'mafupa ndi mafupa, chithandizo cha matenda osakanikirana oyambitsidwa ndi grampol anakhala ndi zamoyo galamu alibe ndi anaerobes (ENT matenda, matenda thirakiti biliary ndi matenda postoperative m'mimba, chifuwa abscess, kukhumba chibayo). Amoxiclav angagwiritsidwe ntchito kupewa septic zovuta pa ntchito ziwalo zam'mimbamo, pelvis, mtima, impso, bile ducts, mu mafupa mchitidwe ndi maxillofacial opaleshoni.

Chenjezo pakugwiritsa ntchito

Amoxiclav zotchulidwa mosamala odwala omwe ali ndi mbiri ya thupi lawo siligwirizana. Pali kuthekera kwa kuyanjana pakati pa ma cephalosporins ndi ma penicillin, chifukwa chake kusamala ndikofunikira popereka Amoxiclav kwa odwala omwe ali ndi vuto la cephalosporins.

Ndi kuphwanya chiwindi, kuyang'anira ntchito yake ndikofunikira.

Mu 95% ya odwala omwe ali ndi matenda opatsirana a mononucleosis ndi lymphocytic leukemia, kugwiritsa ntchito mankhwalawa kumayendera limodzi ndi kukula kwa zotupa pakhungu, motero, sikulimbikitsidwa kupereka Amoxiclav pazinthu izi.

Odwala omwe ali ndi vuto lalikulu la impso, mlingo uyenera kusankhidwa payekhapayekha, mwinanso kukulitsa pakati pakubayidwa jakisoni wa mankhwala.

Pochita ndi Amoxiclav, tikulimbikitsidwa kudya madzi ambiri.

Amoxiclav imapereka zotsatira zabodza popanga kuyesa kwa Benedict (kudziwa shuga mu mkodzo) ndi zomwe Coombs zimachita. Kuyesedwa kwa glucose kochokera mu enzymatic oxidation reaction kumalimbikitsidwa.

Palibe deta pa teratogenic mphamvu ya yogwira zigawo za Amoxiclav. Amoxiclav itha kugwiritsidwa ntchito pa nthawi yoyembekezera malinga ndi mawonekedwe okhwima.

Zochita Zamankhwala

Amoxiclav pakugwiritsa ntchito laberal imagwirizana ndi njira zotsatirazi kulowetsedwa - madzi a jakisoni, isotonic sodium chloride solution, Ringer's lactate solution, potaziyamu chloride solution, Amoxiclav sakhazikika m'malo okhala ndi dextran kapena glucose. Mankhwala sayenera kusakanikirana mu buku limodzi ndi mankhwala ena a makolo.

Amoxiclav 2x - njira yogwiritsira ntchito ndi Mlingo

Orally mapiritsi, mankhwalawa amalimbikitsidwa kwa akulu ndi ana olemera kuposa makilogalamu 40, muyezo wa tsiku ndi tsiku - piritsi 1 375 mg 3 kawiri pa tsiku (maola 8 aliwonse) kapena piritsi 1 625 mg katatu patsiku, kutengera kuchokera kuopsa kwa matenda opatsirana. Mapiritsi a Amoxiclav 2X 1000 mg amagwiritsidwa ntchito mwa odwala akuluakulu omwe ali ndi matenda oopsa kapena kupuma, 1 piritsi 2 kawiri pa tsiku. Kwa ana kuyambira miyezi itatu ndi kupitilira apo omwe ali ndi kulemera kosakwana 40 kg kwa matenda opatsirana opatsirana, Amoxiclav amalembedwa tsiku lililonse 25 mg / kg wogawidwa mu 2 Mlingo uliwonse (maola 12 aliwonse), kapena 20 mg / kg wogawidwa pamiyeso itatu (8 iliyonse h), komanso matenda oopsa - 45 mg / kg, logawidwa mu 2 Mlingo uliwonse (maola 12 aliwonse), kapena 40 mg / kg, wogawidwa pazidutswa zitatu (maola 8 aliwonse). Kwa ana akhanda ndi ana mpaka miyezi itatu, Amoxiclav amalembedwa tsiku lililonse 30 mg / kg (malinga ndi amoxicillin), logawidwa mu 2 Mlingo wofanana.

Mulingo wambiri tsiku lililonse wa amoxicillin wa akulu ndi 6 g, kwa ana - 45 mg pa 1 makilogalamu amalemu amthupi, muyeso wokwanira tsiku lililonse wa clavulanic acid (munthawi ya mchere wa potaziyamu) kwa akulu ndi 600 mg, kwa ana - 10 mg pa 1 kg ya thupi.

Kwa otitis media, sinusitis, matenda am'mimba opatsirana kupuma ndi matenda ena akulu, mlingo woyenera wa ana ndi 45 mg / kg patsiku lililonse (la amoxicillin) maola 12 aliwonse.

Kwa matenda opatsirana pang'ono, mlingo wa tsiku ndi tsiku ndi 25 mg / kg (maola 12 aliwonse).

Mlingo weniweni wa kuyimitsidwa kwa mwana ukhoza kuwerengedwa kokha poganizira kulemera kwa thupi.

Odwala omwe amalephera kwambiri aimpso (creatinine chilolezo chochepera 10 ml / min) amafunika kusintha kwa mlingo kapena kuwonjezeka kwakanthawi pakati pa Mlingo (ndi anuria - mpaka maola 48 kapena kupitilira).

Kwa odwala omwe amalephera kupezeka ndi aimpso (creatinine chilolezo cha 10-30 ml / min), muyezo uyenera kuchepetsedwa mokwanira kapena pakati pakati pa mankhwala muyenera kuchuluka.

Kukonzekera kuyimitsidwa, vial iyenera kugwedezeka bwino (mpaka ufa utasiyanitsidwa ndi makoma ndi pansi pa chotengera), kenako kuwonjezera madzi - 86 ml (kuyimitsidwa kwa Amoxiclav) pamtundu wa 2, kugwedezeka bwino nthawi iliyonse. Supuni imodzi yovomerezeka yolandirira kuyimitsidwa (yophatikizidwa) ili ndi 5 ml, supuni 3/4 - 3.75 ml, supuni 1/2 - 2,5 ya kuyimitsidwa.

Parenteral - mu / akulu ndi ana opitilira zaka 12 (akulemera kuposa makilogalamu 40) - 1,2 g maola 8 aliwonse, chifukwa cha matenda oopsa - maola 6 aliwonse, kwa ana azaka zitatu mpaka zaka 12 - 30 mg / kg maola 8 aliwonse, ali ndi matenda oopsa - maola 6 aliwonse, kwa ana mpaka miyezi itatu - 30 mg / kg maola 8 aliwonse, kwa ana akhanda, kuphatikizapo ana asanakwane - 30 mg / kg maola 12 aliwonse a 30 mg a Amoxiclav Zoyendetsa iv, zimakhala ndi 25 mg ya amoxicillin ndi 5 mg ya clavulanic acid.

Mukakwaniritsa zochizira mothandizidwa ndi Amoxiclav, mutha kusintha mankhwalawo mkati.

Mankhwala a Amoxiclav kwa akulu ndi ana angathe kuchitidwa kwa masiku 14.

Mlingo wa akulu omwe ali ndi vuto la aimpso:

- pomwe imvume ya creatinine imaposa 30 ml / mphindi, palibe chifukwa chochepetsera mlingo wake.

- ndi creatinine chilolezo cha 10-30 ml / min, mankhwalawa amayamba ndi utsogoleri wa 1,2 g, kenaka 600 mg iv ndi maola 12,

- kulephera kwambiri kwa aimpso (kulengedwa kwa creatinine kosakwana 10 ml / mphindi), mankhwalawa amayambitsidwa ndi iv, g, kenako 600 mg iv ndi nthawi ya maola 24. Mwa ana omwe ali ndi vuto la impso, ndikofunikira kuti achepetse mankhwala.

Ndi peritoneal dialysis, kusintha kwa mankhwalawa sikofunikira, pa hemodialysis, pafupifupi 85% ya mankhwalawa amachotsedwa, motero, pambuyo pa njirayi, mankhwalawa amathandizidwa ndi iv mu 600 mg.

Kukonzekera njira yovomerezeka ndi iv, zomwe zili mu vial yomwe ili ndi 600 mg ya Amoxiclav imasungunuka mu 10 ml ya madzi a jekeseni, zomwe zili mu vial yomwe ili ndi 1.2 g ya Amoxiclav mu 20 ml ya madzi a jekeseni, -R imayendetsedwa mkati / mkati pang'onopang'ono (mkati mwa mphindi 3-4). Pa kulowetsedwa kwa mtsempha, kuti 0,6 g (kusungunuka mu 10 ml ya madzi a jekeseni) kapena 1.2 g (kusungunuka mu 20 ml ya madzi a jekeseni) onjezani 50 kapena 100 ml ya kulowetsedwa, motero, jekeseni wamkati mkati 30-30 mphindi Jakisoni wa bolodi wa IV ayenera kuperekedwa mkati mwa mphindi 20 mutakonzekera yankho la jakisoni. Dr osawuma.

Pazifukwa za prophylactic mu opaleshoni, akuluakulu amapaka jekeseni wa 1.2 g wa Amoxiclav mu IV isanachitike opaleshoni chifukwa cha kuchitapo kanthu kwakanthawi kochepa kochita opaleshoni, ndikuchita kwa nthawi yayitali (zoposa 1 h), kuyendetsedwa mobwerezabwereza kwa mankhwala kumafunikira (1,2 g mpaka 4 pa tsiku), Pachiwopsezo chotenga kachilomboka, chithandizo chitha kupitilizidwa pambuyo pake, ndikuwonetsa zizindikiro za matenda nthawi ya opereshoni kapena itatha, Amoxiclav imagwiritsidwa ntchito (kholo kapena pakamwa) mu nthawi ya postoperative.

Mulingo wamba wa tsiku ndi tsiku kwa akulu ndi ana olemera kuposa makilogalamu 40 ndi piritsi limodzi 500 mg / 125 mg kawiri pa tsiku kapena piritsi limodzi 875 mg / 125 mg kawiri pa tsiku.

Zochizira matenda opepuka kapena osakhazikika, njira yofananira ndi piritsi 1 500 mg / 125 mg 2 kawiri pa tsiku (maola 12 aliwonse), kuchitira matenda oopsa - 1 piritsi 500 mg / 125 mg katatu patsiku (maola 8 aliwonse) kapena piritsi limodzi la 875 mg / 125 mg kawiri pa tsiku (maola 12 aliwonse).

Kutalika kwa nthawi ya maphunziridwe ake kumatengera zikuwonetsa, adokotala adatsimikiza ndipo sayenera kupitirira masiku 14.

Mapiritsiwo ayenera kusungunuka kapu imodzi ya madzi (osachepera 100 ml), kusakanikirana bwino musanayambike kapena kutafuna musanameze. Mapiritsi amatengedwa bwino kumayambiriro kwa chakudya.

Odwala omwe ali ndi vuto la impso, chindapusa cha clavulanic acid ndi amoxicillin amachepetsa. Ndikofunikira kuchepetsa mlingo molingana ndi kuopsa kwa magwiridwe antchito komanso / kapena kuwonjezera nthawi yayikulu pakati pa Mlingo.

Odwala omwe amalephera kupezeka ndi aimpso (creatinine chilolezo 0,166-0.5 ml / s) ndi mapiritsi 1 500 mg / 125 mg maola 12 aliwonse.

Odwala omwe amalephera kwambiri aimpso (creatinine chilolezo chochepera 0.166 ml / s) amapatsidwa piritsi limodzi la 500 mg / 125 mg maola 24 aliwonse.

Zotsatira zoyipa

nthawi zambiri imakhala yofatsa komanso yodutsa.

Kuchokera pamimba: Matenda am'mimba: 4.1%), nseru (3%), kusanza (1.8%) ndi dyspepsia (1.6%), kawirikawiri anorexia, flatulence, gastritis, stomatitis, glossitis kapena kusinthika kwa lilime, enterocolitis. Pseudomembranous colitis yoyambitsidwa ndi poizoni wopangidwa ndi Clostridium Hardile imatha kupezeka kapena kusiya mankhwala.

Mbali ya magazi: magazi m'thupi (kuphatikizapo hemolytic anemia), thrombocytopenia, eosinophilia, leukopenia, agranulocytosis.

Kuchokera kumachitidwe amanjenje: kawirikawiri - kupweteka mutu, chizungulire, kusowa tulo, kukwiya, kuda nkhawa, zosayenera, chisokonezo, kupsinjika.

Matenda a hepatobiliary: kuwonjezeka kwa mayesero a chiwindi ndikotheka, kuphatikizapo kuwonjezeka kwa asymptomatic mu ntchito ya AcAT ndi / kapena AlAT, alkaline phosphatase ndi milingo ya serum bilirubin. Kuchepa kwa chiwindi nthawi zambiri kumachitika mwa okalamba kapena odwala omwe amalandila chithandizo kwa nthawi yayitali. Hepatitis ndi cholestatic jaundice ndizosowa. Zizindikiro zake zimachitika nthawi yayitali kapena atangomwa chithandizo, koma nthawi zina mankhwalawa satha kuonekera kwa milungu ingapo atatha chithandizo.

Kuchokera pakhungu: zotupa, urticaria, angioedema, osowa - erythema multiforme, Stevens-Johnson syndrome, exermative dermatitis, poyizoni epermermal necrolysis.

Kuchokera kwamikodzo dongosolo: kawirikawiri - interstitial nephritis ndi hematuria.

Zina: zenizeni vaginitis (1%), kutentha thupi, kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kungayambitse matenda a m'magazi.

Zosiyana ndi zomwe zikuchokera

Radar (registry ya Russian mankhwala) ili ndi chidziwitso chakuti Amoxiclav2X ndi amodzi mwa antibacterial. Onsewa ali ndi mawonekedwe osiyanasiyana ndipo amatha kuletsa kukula ndi kukula kwa mabakiteriya osiyanasiyana okhala ndi tizilombo. Mabakiteriya oterowo amakhala onse opanda gramu komanso gram-negative, aerobes kapena anaerobes. Tizilombo toyambitsa matenda timatha kupezeka pamalo pomwe pali mpweya wabwino ndi momwe mulibe. Chifukwa chake, pogwiritsa ntchito mankhwala omwe tafotokozawa, ndizotheka kuchita zinthu zomwe zingapangitse kuti muthane ndi matenda, zomwe zimapangitsa kuti muthane ndi zomwe ndi:

• khalimotz,
• streptococci,
• enterococci,
• nsomba
• shigella.

Kuchita bwino kumatsimikiziridwa ndi kapangidwe kamankhwala, omwe amatha kutchedwa mosamala komanso osankhidwa bwino.

Zimakhazikitsidwa pazinthu ziwiri zomwe ndizogwira zosakaniza:

1. Amoxicillin. Amanenanso ma anti-synthetic antiotic, amatha kutulutsa zowononga mabakiteriya amitundu yosiyanasiyana, iliyonse yomwe ingayambitse matenda oopsa komanso ovuta.
2. Clavulanic acid ndi gawo lomwe limaphatikizidwa pakuphatikizidwa kwa mankhwalawo kuti ateteze nembanemba ya cell. Imakhalanso ndi gawo linalake la zoletsa zomwe zimawononga ma penicillin.

Kuchita kwapamwamba kwambiri kwa kukonzekera kwa Amoxiclav2X kumatsimikizika chifukwa cha kuyambitsa kwa clavulanic acid mu kapangidwe kake.

Monga zinthu zina zomwe zimayambitsidwa mu Amoxiclav 2X, zotsatirazi zinagwiritsidwa ntchito:

1. Talc ndi polysorbate.
2. Titanium dioxide ndi ethyl cellulose.
3. Croscarmellose sodium.
4. MCC (microcrystalline cellulose).
5. Anhydrous colloidal silicon dioxide.
6. Magnesium stearate ndi crospovidone.

Ngati tikulankhula za ufa womwe umagwiritsidwa ntchito pokonza kuyimitsidwa, ndiye pomwe zimapangidwa ngati zinthu zowonjezera, kununkhira ndi xanthan chingamu, anhydrous citric acid, sodium benzoate zidawonjezeredwa pazomwe zimapangidwa. Ufa womwe umapangidwira kukonzekera kwa 5 ml ya kuyimitsidwa uli ndi 125 mg ya amoxicillin wogwiritsidwa ntchito mwa mawonekedwe a trihydrate ndi 31-32 mg ya clavulanic acid mu mawonekedwe a mchere wa potaziyamu. Kuyimitsidwa kumapangidwira kuti ana azitha zaka 3.

Makamaka kwa odwala akuluakulu, mankhwalawa amapezeka piritsi. Piritsi lililonse limakhala loti lizilimbirana ndi filimu yosungunuka pang'ono. Mlingo wa zosakaniza zogwira ntchito ndi 250/125 mg, 500/125 mg, 875/125 mg. Chiwerengero choyamba chikuwonetsa zomwe amoxicillin, ndipo chachiwiri - zomwe zili mu clavulanic acid.

Kusiyanitsa kwakukulu pakati pa Amoxiclav 2X, komwe kumawasiyanitsa ndi mankhwala ena a antibacterial, ndikuyendetsa kwake kokwanira m'magazi amwazi kumatheka pambuyo pa mphindi 60-180 atatha kumwa mankhwalawo.

Zosakaniza zonse zimasankhidwa poganizira momwe zimagwirira ntchito komanso kuthekera kuthana ndi tizilombo toyambitsa matenda. Malinga ndi malangizo omwe ali mu malangizo a Amoxiclav 2X, muyezo komanso nthawi yomwe mumamwa mankhwala opangidwa ndi piritsi imatsimikizika malinga ndi zomwe wodwala aliyense ali nazo, zaka zake komanso kuopsa kwa matenda omwe wapezeka.

Zochita ndi mawonekedwe

Mabakiteriya a patathogenic amatulutsa enzyme beta-lactamase, yomwe imatha kuwononga penicillin ndi mankhwala ofanana. Kuti tikwaniritse kukhazikika ndi ntchito ya maantibayotiki kuchokera ku mndandanda wa penicillin okhawo omwe aclavulanic acid omwe amaphatikizidwa ndi awo amapanga, omwe amathandizira kwambiri Amoxiclav 2X.

Zogwira ntchito zimalowetsedwa mu mucosa wam'mimba kwa kanthawi kochepa, ndipo kuthamanga kwawo kumafika pamlingo wofunikira kupeza zotsatira zabwino mkati mwa mphindi 20-30 mutatha kutenga piritsi yoyamba.

Kulandila kwa Amoksiklav 2X amaloledwa onse asanadye, komanso nthawi kapena pambuyo pake. Izi ndichifukwa choti chakudya chomwe chalowa m'mimba sichikhudza mbali zomwe zimagwira, chimachedwetsa kuyamwa kwawo mu mucosa wam'mimba. Zizindikiro zazikulu zogwiritsidwa ntchito ndi anti-spectrum antiotic ndi matenda monga:

1. Njira yotupa mu bronchi.
2. Kutupa kwa ziwalo zamkati (khutu lapakati).
3. Njira yopatsirana komanso yotupa m'madipatimenti osiyanasiyana am'mapapu.
4. Pharyngitis. Kutupa kwa m'mimba.
5. Pyelonephritis.
6. Kutupa kwamitseko pamimba ndi cystitis (kutupa kwa chikhodzodzo).
7. Matenda opatsirana komanso otupa a peritoneum ndi ziwalo zam'mimba.
8. Arthrosis ndi kutupa kwa thumba lolumikizana.

Masinthidwe onse a pathological awa ndi omwe amachitika chifukwa choyipa cha mabakiteriya osiyanasiyana okhala ndi tizilombo.

Amakhala opatsirana nthawi zambiri komanso chifukwa cha chithandizo chawo, kugwiritsa ntchito mankhwala ndikofunikira, chizindikiritso chake chimadziwika kuti ndichochita bwino kwambiri. Pankhaniyi, mankhwalawa ndi Amoxiclav2X.

Kupanga mapiritsi Amoxiclav

Zigawo zikuluzikulu:
• amoxicillin ali ndi bactericidal zotsatira,
• clavulanic acid, yomwe imawonetsetsa kuti mankhwalawa amathandizira pakhungu lotupa lomwe limagwirizana ndi amoxicillin.
Zowonjezera:
• talcum ufa salola kuti tinthu tating'onoting'ono tigwirizane ndikuwapatsa mlingo woyenera,
• steric acid amalimbikitsa kutsitsa komanso kuchepetsa kukonzanso kwa phale,
• zonunkhira,
• mchere wa sodium citric acid - imathandiza kuwononga piritsi mwachangu ndi madzi,
• citric acid amagwiritsidwa ntchito mapiritsi am'madzi kuti asungunuke bwino m'madzi.

Contraindication ndi zotheka zovuta

Ngakhale kutchuka kwakukulu, kugwiritsa ntchito bwino kwa Amoxiclav 2X, mawonekedwe ake osankhidwa bwino komanso kuchuluka kwa mikhalidwe yabwino, pali zotsutsana, zomwe zambiri zimadziwika kuti ndizopanda tanthauzo. Ndi zoletsedwa kumwa mankhwalawa kwa odwala omwe ali ndi chifuwa chimodzi mwa zinthu zomwe zimapanga mankhwalawo.

Amoxiclav 2X imakhala ndi zinthu zomwe zimayambitsa kupezeka ndi chitukuko cha anaphylactic mantha, edema ya Quincke, kapena zina. Izi zitha kupha.

Zina mwa zotsutsana mwamtheradi za Amoxiclav 2X ndi kukhalapo kwa wodwala:

1. Kuwonongeka kwakukulu kwa chiwindi ndi impso (aimpso kapena kwa chiwindi).
2. Khansa ya m'magazi.
3. Mononucleosis, yomwe ili ndi matenda.
4. Hypersensitivity kwa penicillin ndi kufanana kwawo.

Kulephera kutsatira malangizo omwe adokotala akupereka ndi kukhudzana mwachindunji ndi malamulo omwera mankhwalawo, komanso kudzikonza nokha pa kumwa mankhwala omwe adasankhidwa ndi katswiriyo, kumabweretsa zotsatirapo zoyipa.

Amawoneka makanema otsutsana ndi ziwalo zosiyanasiyana za thupi:

1. Sinthani mumtundu wa chopondapo (m'mimba).
2. Kuopseza kuchepa madzi m'thupi (dyspepsia).
3. Zowawa m'mimba.
4. Mutu.
5. Zowonongeka ndi kumva.
6. Kutentha kwam malekezero (manja ndi mapazi akunjenjemera).
7. Chizungulire komanso kupweteka kwa minyewa.
8. Kuda nkhawa kosafunikira kapena mantha.

Malangizo okhudza kusiya mankhwala osintha kapena kusintha kwa mankhwala omwe sanasankhidwe koyambirira angaperekedwe kokha ndi katswiri wodziwa bwino kwambiri. Zosintha zonse zokhudzana ndi wodwalayo ziyenera kufotokozedwera kwa adokotala, omwe apange chisankho chotsiriza kapena kupitiriza kwa njira zochiritsira zogwirizana ndi ntchito ya Amoxiclav 2x.

Malamulo olandila komanso njira zapamwamba

Chithandizo chithandizira ngati chichitidwa motsogozedwa ndi kuyang'aniridwa ndi katswiri woyenera. Wodwalayo ayenera kutsatira malangizo omwe adalandiridwa, kutsatira malamulo okhazikitsidwa omwe amamwa mankhwalawo osaphwanya mlingo woyenera wosankhidwa ndi dokotala. Izi zikugwira ntchito kwa odwala azaka zonse, ngakhale gawo la chitukuko ndi kuopsa kwa matendawa:

1. Ana kuyambira wazaka 6 mpaka 12 amapatsidwa theka la piritsi kawiri pa tsiku atadya. Ngati mkhalidwe wa wodwalayo watchulidwa kuti ndi wocheperako kapena wowonda, ndiye kuti mankhwalawa amakwera ndipo pamenepa mwana ayenera kulandira mapiritsi ½ 3 r d.
2. Kwa odwala omwe ali ndi zaka 12, kuchuluka kwa mankhwalawa sasintha mosasamala za msinkhu. Ndikofunikira kudziwa bwino kukula kwa matendawo komanso kuopsa kwake. Kuti mukwaniritse zotsatira zabwino zochizira, odwala amalembedwa mapiritsi a Amoxiclav 2X mu mlingo wa 500/125 mg, imodzi 2 r / d, ndipo muzoopsa, kuchuluka kwa kuchuluka kumawonjezereka mpaka 3 r / d.

Kusankhidwa kwa Mlingo wambiri ndi nthawi yayitali ya zamankhwala zimatengera mawonekedwe a matendawa. Mukuwonjezeka kwa impso, wodwalayo amayenera kupita kuchipatala ndikugwiritsa ntchito mankhwala Amoxiclav2X. Maphunziro oterewa amayambira sabata limodzi kapena awiri. Pofuna kuthana ndi zotupa mu pharynx ndi larynx, muyenera kumwa mankhwalawa kwa sabata limodzi.

Kusiya kuwunika kwawo kwa Amoxiclav 2X, madotolo odziwa zambiri akuti othandizira omwe ali ndi antibacterial amadziwika kuti amatha kulimbana ndi mabakiteriya owopsa kwambiri patatha masiku 7-15.

Odwala amayatsidwa maphunziro a milungu iwiri a antibacterial, omwe zotsatira zake ndi kuchira kwathunthu.

Madokotala amakono apanga ndi kupanga mankhwala omwe atha kukhala m'malo a Amoxiclav 2X. Atapangidwa, maantibayotiki othandizira amagwiritsidwa ntchito ngati zida zogwira ntchito.

Ngati dokotala wakupangiratu akuvomereza kuti musamwe mankhwalawa, ndiye kuti wodwalayo angathe kugula njira yothandizirana kwambiri muchipatala. Kutsegula kotereku kwa Amoxiclav 2X kumapewetsa kukulitsa zovuta komanso kumathandizira kuthana ndi matendawa kwakanthawi kochepa.

Zotchuka komanso zofunidwa kwambiri ndi:

Mtengo wa lirilonse la mankhwalawa umapangitsa kuti akhale okwanira kugula magawo onse a anthu, ndipo magwiridwe antchito ndi chitetezo zimakhala zambiri. Makhalidwe amenewa amachititsa kuti antibacterial mankhwala azikondedwa ndi onse odwala komanso akatswiri odziwa bwino ntchito yawo.

Ndalama zonsezi zimadziwika ndi zochita za antibacterial, zimathandizira kuthana mwachangu ndi mabakiteriya okhala ndi matenda ndikuchotsa matendawa. Kusiyana pakati pawo pamtengo ndi chiwonetsero chochita. Dokotala wodziwa bwino amatha kusankha mankhwala oyenera kwambiri, moyang'aniridwa ndi kuyang'anira momwe mankhwalawo akuchitidwira.

Musanagule analog ya Amoxiclav 2X, muyenera kufunsa dokotala yemwe angakuwuzeni mlingo woyenera wa mankhwalawo. Maganizo a katswiri woyenereradi amakhala njira yayikulu pakusankhira mankhwala. Mutha kufotokoza chilichonse chokhudzana ndi kapangidwe ka mankhwalawo, kuchuluka kwa muyezo komanso ndandanda ya kudya pang'onopang'ono mwakuwunikira zomwe zili mu malangizo ogwiritsira ntchito mankhwalawa.

Dzinalo Losayenerana

Mu gulu la World Health Organisation, dzina ladziko lonse Amoxiclav limasinthidwa - Amoxicillin + Clavulanic acid (Amoxicillin + Clavulanic acid).

Amoxiclav 2x ndi mankhwala ophatikiza a antibacterial omwe adapangidwa pamaziko a amoxicillin ndi potaziyamu clavulanate.

Mayina amalonda

Kuphatikizika kwa zinthu zogwira ntchito pamsika wamankhwala kumapangidwa pansi pa mayina awa: Amoxiclav Quiktab (mawonekedwe omaliza), Augmentin, Panklav, Panklav 2x (ndi kuchuluka kowonjezera), Flemoxin Solutab, Ecoklav ndi ena.

Mukasinthira mankhwala oyambirirawo, muyenera kuphunzira mosamala malangizo ogwiritsa ntchito analogue kupezeka kwa ochulukitsa ndikutsatira mlingo womwe ukufunika.

2 Mawonekedwe ake ndi mitundu

Mapiritsi okhathamira othandiza kuti asungunuke pakamwa amapangidwira pakamwa ndipo amapezeka mu mitundu iwiri:

• 500 mg + 125 mg, kwathunthu - 625 mg, osankhidwa 500/125,
• 875 mg + 125 mg, ponseponse - 1000 mg (875/125).

Mapiritsi okhala ndi zotumphukira amapezeka mu Mlingo wa 875 mg + 125 mg.

Zowonjezera pazomwe zimapangidwira phukusi la piritsi ndi chipolopolo: silicon dioxide, polysorbate, magnesium stearate, crospovidone, croscarmellose sodium, triethyl citrate, hydroxypropyl cellulose, titanium dioxide (E171), talc, MCC.

4 Mankhwala

Clavulanic acid ndi mankhwala ofooka ofooka ndipo mwanjira yofanana ndi gulu la beta-lactam. Udindo wake pakukonzekera kophatikiza ndikuteteza amoxicillin kuti asawonongeke.

Ma Enzymes opangidwa ndi mabakiteriya ena (beta-lactamases) amateteza tizilombo toyambitsa matenda ku maantibayotiki. Chifukwa chake, pali zovuta zophatikiza ndi mankhwala.

Clavulanate amathetsa vutoli poletsa mabakiteriya omwe amatsutsa - kumanga β-lactamases ndikuwachotsa m'thupi. Zotsatira zosiyanasiyana za amoxicillin zimawonjezeka chifukwa chogwiritsidwa ntchito munthawi yomweyo ndi inhibitor.

Magulu a mabakiteriya otsatirawa ali ndi chidwi chotsatira chakukonzekera kwazinthu ziwiri:

• gram-aerobes wabwino (streptococci, listeria, enterococci, ena staphylococci),
• gram-negative aerobes (Haemophilus influenzae, Gardnerella vaginalis, Salmonella spp., Shigella spp., Helicobacter pylori, Brucella spp, Pasteurella multocida, Proteus spp. ndi ena),
• tizilombo toyambitsa matenda a anaerobic gram-positive (Clostridium spp., Peptococcus spp., Peptostreptococcus spp., Clostridium spp., Fusobacterium spp., Prevotella spp.),
• Gram-hasi anaerobic okhala ndi ndodo yowumbidwa ndi ndimu (Bacteroides spp., Fusobacterium spp.).

Mphamvu yotsutsa ya amoxicillin imayamba chifukwa chophwanya kukhulupirika kwa nembanemba wa bakiteriya ndi kuyamwa kwa maselo a pathogen. Amaloŵereratu msanga m'mimba, ngakhale zakudya, zakudya zamafuta zimalowa m'matupi athu onse komanso zakumwa zamthupi. Kuzindikira kwakukulu kumawonedwa mphindi 60 kuchokera pakamwa.

Zinthu zonsezi zimapangidwa makamaka ndi impso: amoxicillin osasinthika, clavulanate mu mawonekedwe a metabolites opangidwa m'chiwindi.

5 Zomwe zimathandiza Amoxiclav 2x

Kuchuluka kwa amoxicillin piritsi limodzi la mankhwalawa amapangidwira kuti azigwiritsidwa ntchito mozama: ndi matenda owopsa, zotupa zosakhalitsa, kupezeka kwa tizilombo toyambitsa matenda angapo kapena chifukwa chosatitsimikizira.

Mankhwala omwe akufunsidwa amapatsidwa bronchitis.

Fotokozani mankhwala a bakiteriya omwe amayamba ndi machitidwe ndi ziwalo:

• mbali zam'munsi za broncho-pulmonary system: tonsillitis, chibayo, bronchitis, pleurisy,
• Ziwalo za ENT: sinusitis, atitis media, pharyngeal abscess,
• m`kamwa ndi maxillofacial dera: periodontitis, pulpitis, maxillary phlegmon,
• genitourinary system: kwamikodzo thirakiti, matenda am'mimba, matenda amkodzo, kuphatikizapo chinzonono, chancre,
• minofu yofewa ndi khungu: kutupa kwatsuka, mabala opatsirana, furunculosis,
• minofu: mafupa a m'mafupa ndi mafupa,
• matenda osakanikirana a biliary thirakiti, mtima dongosolo, abscesses osiyanasiyana kutulutsa.

Amoxiclav imagwiritsidwa ntchito popewa matenda opatsirana pambuyo pachitetezo cha opaleshoni yam'mimba, pelvis yaying'ono, mtima, mafupa, opaleshoni ya maxillofacial ndi mano.

6 Momwe mungatenge Amoxiclav 2x

Piritsi lamakono lamankhwala omwe amapezeka ndi kuchuluka kwa mankhwalawa amangolembedwa kwa odwala akuluakulu (azaka zopitilira 12) okhala ndi thupi loposa 40 kg. Zochizira ana, othandizira apadera amapangidwa m'njira yoyimitsa pakamwa. Ufa wokonza njira yothetsera vutoli umapezeka mosavuta kutengera kulemera kwa mwana, Dokotala wa ana amawerenga kuchuluka kwa zinthuzo.

Amoxiclav (1000 mg) yopuma komanso matenda ena owopsa amapatsidwa piritsi 1 lililonse maola 12.

Amoxiclav (1000 mg) yopuma komanso matenda ena owopsa amapatsidwa piritsi 1 lililonse maola 12. Pa mlingo wofanana ndi 500 mg wa antibayotiki, mankhwalawa amatengedwa maola 8 aliwonse.

M'mikhalidwe ya zolimbitsa kukula kapena kuwonongeka kwa chapamwamba kupuma thirakiti (sinusitis, sinusitis, tonsillitis), amoxiclav 500/125 katatu patsiku ndi zofanana magawo.

Mukamapereka mapiritsi a 875/125, sizovomerezeka kuti amangosintha mwachisawawa mapiritsi ena ochepa.

Mlingo wambiri wa clavulanic acid umachulukitsa matenda.

Njira ya mankhwala ophatikiza ndi antioxotic ndi kuyambira masiku 5 mpaka 7 ndipo imangowonjezeredwa pokhapokha ngati dokotala akuwalimbikitsa. Mulingo wovomerezeka wa mankhwala omwe amatengedwa patsiku sayenera kupitirira 6 g malinga ndi amoxicillin.

Malangizo apadera

Mlingo wa kuthetsedwa kwa mankhwala ophatikiza umatsika molingana ndi kuchepa kwa impso. Pamene creatinine chilolezo chimakhala chochepera 10 ml / min, kukonza kwa nthawi imodzi kumachitika kapena kupangika kwapakati.

Kulephera kwakukulu kwa aimpso, piritsi limodzi (1 g) la mankhwalawa limatengedwa maola 24 aliwonse.

Kulephera kwakukulu kwa aimpso, kuthetseratu theka la moyo wa amoxicillin kumachepetsa mpaka maola 7-8. Zikatero, piritsi limodzi (1 g) limatengedwa maola 24 aliwonse, moyang'aniridwa ndi dokotala. Kwa odwala ochepetsedwa diuresis, nthawi yapakati pakati Mlingo imatha kuchuluka kwa masiku awiri.

Popereka mankhwala ochuluka a amoxicillin, odwala omwe ali ndi makodzo osakanikirana a mkodzo amayenera kuwunika kuchuluka kwa catheter. Mankhwala amakhala ndi katundu wokhazikika pamakoma ndikuchepetsa kutulutsa madzi.

Zotsatira zoyipa za Amoxiclav 2x

Kuphatikiza kwa zinthu zomwe zimagwiritsidwa ntchito mosiyanasiyana, zoyesedwa mwachipatala, zimalekeredwa bwino ndi odwala. Zotsatira zoyipa ndizosowa. Madandaulo am'mimba (mu 9% ya odwala), nseru ndi zotupa pakhungu (3%), ndikusanza adadziwika mu 1% ya milandu yonse.

Chiwerengero cha yogwira pophika mankhwala 7: 1 chimachepetsa kuchuluka kwa zoyipa ndi theka poyerekeza ndi mitundu yomwe imatengedwa pafupipafupi 2 pa tsiku.

Mwa zotheka zosatheka ndi mankhwalawa, amanenanso: kupweteka mutu, kutupa, impso ndi chiwindi, matupi awo owonetsa zovuta.

Zotsatira zoyipa zingasonyeze kusalolera kwa mankhwalawo kapena mankhwala osokoneza bongo. Kukhazikika kwa matendawa kumafunikira kuyezetsa kuchipatala msanga kuti musinthe mankhwalawo m'malo mwake.

Prem Amoxiclav 2x imatha kupweteketsa mutu.

Kutalika kwa nthawi yayitali kumatha kutsatiridwa ndi kuphwanya matumbo ndi microflora yamatumbo, kukula kwa mphamvu, kuphatikizirana kwa nephritis, hematuria, crystalluria.

9 Kutsutsana

Mgwirizano wotsutsana kwathunthu ku Amoxiclav ndi mlingo wowonjezereka ndi zinthu:

• matenda mononucleosis,
• Mavuto a chiwindi omwe amadalira antioxotic, cholestatic jaundice,
• omwe kale anali osagwirizana ndi mankhwala a beta-lactam (kuphatikiza penicillin ndi cephalosporins),
• lymphocytic leukemia.

Pa nthawi yoyembekezera komanso mkaka wa m`mawere, mawonekedwe a piritsi amatha kuperekedwa pokhapokha akuwonetsa mosamala. Odwala omwe ali ndi mbiri ya pseudomembranous colitis amawalandira mosamala.

Kutsutsana kotheratu pakusankhidwa kwa Amoxiclav ndiko kuwonongeka kwa chiwindi komwe kumadalira mankhwala.

10 Mankhwala osokoneza bongo

Mankhwala osokoneza bongo amatha kuyambitsa chithandizo chambiri, kupitirira Mlingo woyenera kapena kuwonongeka kwa chinthu m'thupi. Zizindikiro za mankhwala owonjezera amatha kukhala osagwirizana (kuyambira pachiwopsezo mpaka pakhungu), kupweteka mutu, kukokana (kawirikawiri), nkhawa, komanso kusowa tulo.

Palibe mankhwala enieni; chithandizo ndichizindikiro. Ndi chizindikiro chodziwika bwino cha mankhwala osokoneza bongo, muyenera kuyitanitsa dokotala, kutsuka m'mimba mwanu ndi kutenga enterosorbents. Woopsa milandu, hemodialysis akhoza kuwonetsedwa. Milandu yamankhwala osokoneza bongo opezeka ndi zakupha sizinalembedwe.

11 Kuchita Zinthu Mosagwirizana

Kugwiritsa ntchito munthawi yomweyo mankhwala ndi Amoxiclav kumatheka pokhapokha pakugwirizana ndi adokotala. Amoxiclav imatha kudutsa pamtanda ndi zinthu zamagulu osiyanasiyana.

Zotsatira zina

• Kuchuluka kwa kawopsedwe ndi methotrexate.
• Kuchepetsa mayamwidwe ndi mankhwala ofewetsa tuvi tolimba, aminoglycosides, ma antacid.
• Kulimbikitsa machitidwe a anticoagulants akaphatikizidwa palimodzi.
• Kuchepetsa mphamvu ndi ma tetracyclines, macrolides, sulfonamides.
• Kuchulukitsa kwa ma antioxotic ndi zinthu zomwe zimalepheretsa katulutsidwe ka tubular.
• The kuchuluka kwa immunosuppressants (makamaka, mycophenolate mofetil) amachepetsa mu odwala omwe akupatsidwa chiwalo ndi minofu kupatsirana.
• Mphamvu ya njira zakulera zam'kamwa zimachepetsedwa.

Kutenga Amoxiclav 2x kungachepetse mphamvu ya njira zakulera zamkamwa.

Amoxiclav sagwiritsidwa ntchito limodzi ndi disulfiram, allopurinol, rifampicin.

Mothandizidwa ndi ascorbic acid imathandizira kuyamwa kwa maantibayotiki m'mimba.

Ndi mowa

Amoxiclav osakanikirana ndi mowa amachititsa antabuse, momwe mawonekedwe owopsa onse a mankhwala ndi mowa amachuluka. Kugwiritsa ntchito kwa antibayotiki pakulimbana ndi matenda kumachepetsedwa kwambiri, ndipo zotsatira zoyipa zamafayidwe amthupi (chiwindi, impso) zikuchulukirachulukira.

• nseru, kutsegula m'mimba, kusanza,
• kuthamanga kwa magazi pankhope, khungu rede, chizungulire,
• kupuma pang'ono mpaka kugwedezeka kwa anaphylactic,
• dontho lakuthwa la kuthamanga kwa magazi, tachycardia, bradycardia.

Intoxication imatha kuchitika nthawi yomweyo kapena kuchedwa. Zomwe zimachitika pakamwa mowa wophatikizana ndi Amoxiclav sizikudziwika ndipo sizodalira mphamvu kapena mtundu wa chinthu chomwe chili ndi mowa.

Kugwiritsa ntchito Amoxiclav 2x ndi mowa kumatha kuyambitsa kusanza.

Kuyanjana ndi mankhwala ena ndi mitundu ina yoyanjana

Kugwiritsa ntchito nthawi imodzi phenenecid osavomerezeka. Probenecid amachepetsa impso ya katulutsidwe wa amoxicillin. Kugwiritsa ntchito nthawi yomweyo ndi Amoxiclav ® 2X kungayambitse kuchuluka kwa amoxicillin m'madzi am'magazi nthawi yayitali, koma sikukukhudza kuchuluka kwa clavulanic acid.

Kugwiritsa ntchito nthawi imodzi allopurinol mankhwalawa ndi amoxicillin kuonjezera mwayi wawo sayanjana. Palibe chidziwitso pakugwiritsa ntchito nthawi yomweyo allopurinol ndi Amoxiclav ® 2X.

Monga maantibayotiki ena, Amoxiclav ® 2X imatha kukhudza matumbo, zomwe zimapangitsa kutsika kwa estrogen reabsorption komanso kuchepa kwa magwiridwe antchito opatsirana pakamwa.

Malipoti olekanitsidwa akuwonetsa kuwonjezeka kwa mulingo wofanana wa Internationalisedised ratio (INR) mwa odwala omwe akuchiritsidwa acenocoumarol kapena warfarin ndi kumwa amoxicillin. Ngati kugwiritsa ntchito koteroko ndikofunikira, nthawi ya prothrombin kapena mulingo wa INR uyenera kuyang'aniridwa mosamala ndi kuwonjezera kapena kutha kwa mankhwalawa ndi mankhwala osakanikirana omwe ali ndi amoxicillin.

Amoxiclav ® 2X sayenera kugwiritsidwa ntchito ndi bacteriostatic chemotherapeutic agents / maantibayotiki (chloramphenicol, macrolides, tetracyclines kapena sulfonamides), kuyambira mu vitro ndi kuphatikiza koteroko, zotsatira zoyipa zimawonedwa.

Kugwiritsa ntchito nthawi imodzi Amoxiclav ® 2X ndi methotrexate kuonjezera kawopsedwe wa chomaliza (leukopenia, thrombocytopenia, ulceration pakhungu).

Ndi munthawi yomweyo kugwiritsa ntchito amoxicillin ndi clavulanic acid ndi mycophenolate mofetil kuchepa kwa ndende yogwira IFC metabolite mu plasma ndi 50% akuti.

Zolemba zogwiritsira ntchito

Musanayambe kugwiritsa ntchito mankhwala osokoneza bongo, ndikofunikira kudziwa bwino kupezeka kwa mbiri ya hypersensitivity zimachitikira ku penicillin, cephalosporins kapena allergen ena.

Zoopsa, nthawi zina zakupha za hypersensitivity (anaphylactic reaction) zimawonedwa mwa odwala pa penicillin. Kusintha uku ndikofunika kwa anthu omwe ali ndi vuto lomwelo la penicillin m'mbuyomu. Ngati thupi lanu siligwirizana, siyani chithandizo ndi mankhwalawo ndikuyamba njira ina.

Ngati zikutsimikiziridwa kuti matendawa adayamba chifukwa cha tizilombo tating'onoting'ono tokhala ndi amoxicillin, ndikofunikira kuyeza kuthekera kosintha kuchokera ku kuphatikiza kwa amoxicillin / clavulanic acid kupita amoxicillin malinga ndi kuvomereza kwa boma.

Njira iyi ya Amoxiclav ® 2X siyenera kukhazikika ngati pali chiopsezo chachikulu chakuti tizilombo toyambitsa matenda sitingathe β-lactams ndipo sitigwiritsidwa ntchito pofuna kuchiza chibayo choyambitsa matenda a penicillin. S. chibayo.

Mankhwalawa sayenera kuperekedwa chifukwa cha matenda opatsirana omwe akuwoneka kuti ali ndi matenda opatsirana pogonana.

Kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumatha kupangitsa kukula kwa microflora kukhala kosazindikira kwa Amoxiclav ® 2X komanso kukulira kwa pseudomembranous colitis yamitundu yosiyanasiyana. Pamaso pa kutsekula kwambiri m'mimba pambuyo pakugwiritsa ntchito antimicrobial othandizira, ndikofunikira kuonetsetsa kuti sizikugwirizana ndi matenda awa. Mankhwala omwe amapondereza peristalsis amatsutsana. Ngati colitis yokhudzana ndi maantibayotiki, chithandizo chikuyenera kuyimitsidwa nthawi yomweyo, kukaonana ndi dokotala ndikuyamba chithandizo choyenera.

Ndi kugwiritsa ntchito mankhwalawa kwa nthawi yayitali, monga maantibayotiki ena otchuka, kupatsirana kwakanema ndi mabakiteriya osagonjetseka ndi nkhungu ndizotheka (Pseudomonas spp, Candida albicans) zomwe zimafuna kusiya ntchito kwa mankhwala ndi kugwiritsa ntchito mankhwala ena.

Ndi chithandizo chazitali, timalimbikitsidwa kuwunika ntchito ya ziwalo ndi ziwalo zamagulu, kuphatikizapo aimpso, chiwindi ndi hematopoietic.

Kukula kwa polymorphic erythema yolumikizana ndi mafinya kumayambiriro kwa chithandizo chitha kukhala chizindikiro cha pachimake pantulosis yodziwikiratu. Pankhaniyi, ndikofunikira kusiya mankhwala ndikugwiritsanso ntchito amoxicillin ndikupangidwanso.

Nthawi zina, odwala omwe amatenga Amoxiclav ® 2X ndi anticoagulants pakamwa amatha kukumana ndi nthawi yayitali ya PV (kuchuluka kwa INR). Mothandizidwa ndi anticoagulants munthawi yomweyo, kuwunika koyenera ndikofunikira. Kusintha kwa mlingo wa anticoagulants pamlomo kungafunikire kuti mulingo woyenera wa anticoagulation.

Mankhwalawa ayenera kugwiritsidwa ntchito mosamala odwala omwe ali ndi vuto la chiwindi (onani Magawo "Mlingo ndi Kapangidwe", "Contraindication", "Adaction Reaction"). Zotsatira zoyipa za chiwindi zimachitika makamaka mwa abambo ndi odwala okalamba ndipo amagwirizana ndi chithandizo cha nthawi yayitali. Mu ana, zochitika zoterezi zimanenedwa kuti si kawirikawiri. M'magulu onse a odwala, zizindikiritso ndi zizindikiro zimachitika nthawi yayitali kapena atangomaliza kulandira chithandizo, koma nthawi zina adawoneka miyezi ingapo chithandizo chitaletsa. Mwambiri, zochitika izi zinali zosiyana.

Kwa odwala omwe ali ndi vuto la impso, ndikofunikira kusintha mlingo mogwirizana ndi kuchuluka kwa kuwonongeka (onani Gawo "Mlingo ndi Administration").

Odwala ndi yafupika mkodzo excretion, crystalluria sangathe kuonedwa, makamaka ndi kholo makonzedwe a mankhwala. Chifukwa chake, kuti muchepetse chiopsezo cha mankhwalawa pakumwa mankhwalawa, tikulimbikitsidwa kuti pakhale pakati pa zakumwa zoledzeretsa ndi mkodzo wothira (onani gawo "Overdose").

Mukamagwiritsa ntchito Mlingo wambiri, amoxicillin amatha kulowa mu catheter womwe unalowetsedwa mu chikhodzodzo. Zikatero, kuyang'anira wowona catheter ndikofunikira.

Pochizira amoxicillin, kusintha kwa enzymatic ndi gluidose oxidase kuyenera kugwiritsidwa ntchito kuti mupeze kuchuluka kwa shuga mumkodzo, popeza njira zina zimatha kupereka zotsatira zabodza.

Kukhalapo kwa clavulanic acid pakukonzekera kungayambitse kumangika kwa IgG ndi albumin pamatumbo a erythrocyte, chifukwa chake, zotsatira zabodza zimatha panthawi ya mayeso a Coombs.

Pali malipoti a zotsatira zoyesa zabodza za kukhalapo kwa Aspergillus Odwala omwe amalandila amoxicillin / clavulanic acid (akamagwiritsa ntchito Bio-Rad Laboratories Platelis Aspergillus Mayeso a EIA). Chifukwa chake, zotsatira zabwino ngati izi kwa odwala omwe amalandira amoxicillin / clavulanic acid ziyenera kutanthauziridwa mosamala ndikutsimikiziridwa ndi njira zina zodziwira matenda.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Palibe deta pa teratogenic mphamvu ya mankhwalawa.

Pakufufuza kwina komwe kumachitika mwa azimayi omwe ali ndi matuza a mwana wosabadwayo, adanenanso kuti kugwiritsa ntchito mankhwalawa kungaphatikizidwe ndi chiopsezo chowonjezereka cha necrotizing enterocolitis mwa akhanda.

Magawo onse omwe amagwira mankhwalawa amachotseredwa mkaka wa m'mawere (palibe chidziwitso chokhudzana ndi mphamvu ya khansa ya mwana wachisila). Chifukwa chake, kutsekula m'mimba ndi fungal matenda a mucous zimatha kupezeka mwa mwana, chifukwa chake kuyamwitsa kuyenera kusiyidwa.

Kugwiritsa ntchito Amoxiclav ® 2X pa nthawi yoyamwitsa kumatheka pokhapokha kuwunika mozama pazotsatira / zoopsa.

Kutha kukopa momwe zinthu zikuyendera mukamayendetsa magalimoto kapena njila zina

Kafukufuku wokhudzana ndi mphamvu ya mankhwalawa kuti akhudze kuchuluka kwa magalimoto pamene magalimoto oyendetsa kapena njira zina sizinachitike. Komabe, zimachitika zoyipa (mwachitsanzo, kusintha kwa thupi, chizungulire, kupweteka) zimatha kuchitika zomwe zimatha kukhudza kuyendetsa galimoto kapena njira zina.

Mlingo ndi makonzedwe

Mankhwalawa ayenera kugwiritsidwa ntchito malinga ndi malingaliro omwe boma likuthandizira pakubwera kwa mankhwalawa. Kuzindikira kwa amoxicillin / clavulanate kumasiyana madera osiyanasiyana ndipo kumatha kusintha pakapita nthawi. Ngati ndi kotheka, onani zambiri zam'mudzimo ndipo, ngati kuli kotheka, khalani ndi mayeso pamagetsi oyesera. Mlingo wa mulingo wofotokozedwa umatengera tiziromboti tomwe tikuyembekezeredwa ndi chidwi chake cha antibacterial mankhwala, kuopsa kwa matendawo ndi komwe matenda amatenga, zaka, kulemera kwa thupi ndi impso ntchito ya wodwalayo.

Akuluakulu ndi ana olemera ≥ 40 kg, mlingo wa tsiku ndi tsiku ndi 1500 mg wa amoxicillin / 375 mg wa clavulanic acid (mapiritsi atatu) akaperekedwa motere.

Kwa ana azaka 6 mpaka 6 kulemera kwa 25 mpaka 40 kg, mlingo waukulu wa tsiku ndi tsiku ndi 2400 mg wa amoxicillin / 600 mg wa clavulanic acid (mapiritsi 4) akaperekedwa motere.

Ngati mulingo wambiri wa amoxicillin ayenera kutumikiridwa kuti apatsidwe mankhwala, mitundu ina ya mankhwalawa iyenera kugwiritsidwa ntchito popewa kusankha mankhwala osafunikira kwambiri a clavulanic acid.

Kutalika kwa mankhwalawa kumatsimikiziridwa ndi dokotala malinga ndi momwe wodwala amayankhira chithandizo. Matenda ena (mwachitsanzo osteomyelitis) amafuna chithandizo cha nthawi yayitali.

Akuluakulu ndi ana olemera ≥ 40 kg

1 piritsi 500 mg / 125 mg katatu patsiku.

Ana a zaka zapakati pa 6 ndi thupi lolemera 25 mpaka 40 kg

Mlingo kuchokera 20 mg / 5 mg / kg / tsiku mpaka 60 mg / 15 mg / kg / tsiku, logawidwa pazigawo zitatu.

Popeza piritsi silingagawidwe, kwa ana omwe matupi awo ndi ochepera 25 kg, mtundu uwu wa Amoxiclav ® 2X suyenera kutumikiridwa.

Odwala okalamba

Kusintha kwa Mlingo kwa okalamba sikofunikira. Ngati ndi kotheka, sinthani mlingo wa mankhwalawo kutengera ntchito ya impso.

Mlingo wa matenda aimpso

Mlingo umatengera kuwerengera kwa mulingo wambiri wa amoxicillin. Palibe chifukwa chosinthira mlingo kwa wodwala ndi CC> 30 ml / min.

Akuluakulu ndi ana olemera ≥ 40 kg

Mapiritsi Amoxiclav mapiritsi

• impholeukemia,
• mononucleosis ya mawonekedwe opatsirana,
• cholestatic jaundice,
• hepatitis, wopangidwa atamwa mankhwala a antibacterial a penicillin gulu,
• ziwopsezo zama antibayotiki zamagulu ochepa a cephalosporins, penicillin ndi mankhwala ena a beta-lactam,
• Hypersensitivity ku clavulanic acid kapena amoxicillin.

Tcherani khutu! Mu milandu yaimpso kuwonongeka, aimpso ntchito ndi matenda a pseudomembranous colitis, amaletsa kupitirira mlingo wa mankhwala.

Mapiritsi a Amoxiclav 125 - malangizo ogwiritsidwa ntchito

Zisonyezero zochizira ndi Amoxiclav 125:
• matenda opuma,
• matenda a kwamikodzo,
• zotupa zapakati pa matenda a azimayi,
• Matenda opatsirana pogonana,
• odontogenic matenda.
Mankhwalawa aledzera kumayambiriro kwa chakudya. Amachita izi kuti achulukitse kuyamwa kwa chinthucho komanso kuchepetsa kupsa mtima kwake pamatumbo.

Ndi mlingo wa 125 mg wa amoxicillin, mankhwalawa amatha kupezeka mwa kuyimitsidwa. Amagwiritsidwa ntchito pochiza matenda a bacteria. zomwe sizigwirizana ndi amoxicillin. Kwa ana, mlingo wa Amoxiclav 125 / 31,5 mg amawerengedwa kuti: 40 mg ya mankhwalawa pa 1 kg ya kulemera kwa thupi. Voliyumu imagawidwa mu Mlingo wa 2-3 tsiku lonse.

Zotsatira zakugwiritsa ntchito Amoxiclav 375 mg mwa akulu ndi ana opitilira zaka 12 ndi masekeli oposa 40 kg zimawonedwa pochiza matenda am'mapapo. Tengani piritsi limodzi katatu patsiku limodzi ndi maola 8. Ndi chotupa cha odontogenic, kupuma kumatha kukhala maola 12.
Kwa odwala okalamba, kusintha kwa mlingo sikofunikira.
Ndi vuto pantchito ya impso ndi kugwa kwa creatinine, mankhwalawa amayankhidwa 1-2 pa tsiku. Popanda kukodza, nthawiyo imakulitsidwa mpaka masiku awiri kapena kupitirira apo.
Zochita Zosiyana:
• kutsekula m'mimba,
• Mutu
• candidiasis,
• nseru
• kusanza,
• kuyabwa, ming'oma.
Nthawi ya chithandizo ndi masiku osachepera asanu. Zizindikiro zooneka ngati matendawa zitatha, mankhwalawo amatengedwa kwa masiku ena awiri.

Amoxiclav mapiritsi 500 mg - malangizo ntchito

Mapiritsi okhala ndi gastroprotective ayenera kumezedwa lonse ndi madzi ambiri. Mitundu yosungunuka ya mankhwalawa imayenera kuyamwa mpaka itasungunuka kwathunthu.
Mankhwala ndi ntchito ngati:
• zotupa zapathengo za chapamwamba (sinusitis, otitis media) kapena m'munsi (bronchitis, chibayo, ndi zina).
• Matenda opatsirana a pakhungu, minofu yofewa, mafupa ndi zotumphukira,
• matenda a kwamikodzo (cystitis, urethritis ndi ena), zotupa za m'mimba (endometritis, salpingitis, ndi zina).
• Matenda opatsirana pogonana,
• matenda a monogenic.

Akuluakulu ndi achinyamata opitirira zaka 12 akuwonetsedwa kapisozi 1 maola 12 aliwonse masiku 5 mpaka 14. Ndi zovuta za mankhwalawa, mankhwalawa amadya maola 8 aliwonse. Zizindikiro zitatha, mankhwalawo amatengedwa kwa masiku ena awiri. Pafupifupi, chithandizo chimatenga masiku 5-14. Kulandila sikuloledwa kwa milungu yopitilira ziwiri, popanda kukambirana kwina.
Imwani mankhwala musanadye kapena koyambirira kwa chakudya.

Mapiritsi a Amoxiclav 625 - malangizo angagwiritsidwe ntchito

Zogwiritsidwa ntchito pochiza:
• Matenda opatsirana matenda opatsirana,
• Kutupa kwam'mimba
• cholecystitis ndi cholangitis,
• prostatitis,
• tonillitis, pharyngitis, otitis media, chibayo, bronchitis,
• zotupa zopatsirana za odontogenic.

Mwana wamkulu wazaka zopitilira 12 ndi akulu amapatsidwa piritsi limodzi kawiri pa tsiku, ndi zovuta - 1 kapisozi katatu pa tsiku. Nthawi zambiri, chithandizo chimatenga pafupifupi masiku 7 mpaka 14.
Imwani mankhwalawa pakudya pamene mukumwa madzi ambiri. Mapiritsi sayenera kutafuna. Mapiritsi omwera Amoxiclav musanagwiritse ntchito kupasuka mu 30-50 ml ya madzi.

Mapiritsi a Amoxiclav 875 - malangizo ogwiritsira ntchito

Ntchito mankhwalawa opatsirana am'mapapo komanso matenda amtundu, matenda a m'mimba ndi matenda opatsirana pogonana, matenda opatsirana a patontogenic.

Mlingo wa mankhwala umatsimikizika malinga ndi kukhalapo kwa matenda a impso, kulemera kwake komanso msambo:
• achikulire ndi ana kuyambira zaka 12 ndi masekeli opitilira 40 - piritsi 1 katatu patsiku,
• ndi zovuta, mulingo wowirikiza pawiri,
• pamavuto a mkodzo kutuluka, nthawiyo imakulitsidwa mpaka maola 48.
Mankhwala amatengedwa kwa masiku 5-10 asanadye. Njirayi imalimbikitsidwa kuti muchepetse zovuta pazakudya zam'mimba ndikusunga chokwanira chokwanira chogwiritsira ntchito zinthu.

Mapiritsi a Amoxiclav 2x - malangizo

Kuphatikiza pa amoxicillin (875 mg) ndi clavulanic acid (125 mg), mapiritsi a 875 mg / 125 mg ali ndi:
• talc (2.814 mg),
• ethyl cellulose (1.134 mg),
• cellcose wa microcrystalline (mpaka 1435 mg),
• polysorbate 80 (1.26 mg),
• anhydrous colloidal silicon dioxide (12 mg),
• crospovidone (61 mg),
• titanium dioxide (12.286 mg),
• croscarmellose sodium (47 mg),
• magnesium stearate (17.22 mg).
Kuchuluka kwa okhutira kumasiyana malinga ndi kuchuluka kwa mankhwalawa (250 mg / 125 mg, 500 mg / 125 mg, 875 mg / 125 mg).

Kugwiritsa ntchito mankhwalawa kumakhala koyenera chifukwa cha matenda owopsa komanso opatsirana:
• kupuma dongosolo - tonsillitis, chibayo, bronchitis, pleurisy,
• ziwalo za ENT - otitis media, sinusitis,
• pamlomo wamkamwa - periodontitis, pulpitis,
• ziwalo zoberekera - genatitis, chinzonono,
• khungu ndi minofu yofewa - kutupa kwamkaka, furunculosis.

Mapiritsi okhala ndi kuchuluka kwa zomwe zimagwiritsidwa ntchito amagwiritsidwa ntchito pokhapokha ngati achikulire ndi ana omwe ali ndi masekeli oposa 40 kg omwe ali ndi matenda opumira ndi zina:
• piritsi limodzi (1000 mg) katatu patsiku,
• 500 mg katatu patsiku ndi nthawi osachepera maola 8.
Mankhwalawa ali ndi mawonekedwe:
• kuchuluka kwa mankhwalawa kumadziwika ndi piritsi lalikulu,
• nthawi yomweyo ndizoletsedwa kupatukana, kuluma kapena kuswa kukhulupirika kwa kapisozi
• piritsi liyenera kumezedwa lonse, kutsukidwa ndi madzi,
• kuwonjezera kuchuluka kwa madzi omwe amwe mankhwalawa mpaka malita awiri patsiku,
• imwani ma probiotic molingana (Bifiform, Linex, Lactobacterin, Enterol, Hilak Forte, Acipol, ndi zina).
Mapiritsi ayenera kumwedwa musanadye kapena kumayambiriro kwa chakudya. Njira yogwiritsira ntchito maantibayotiki ndi masiku 5-7.

Mapiritsi a Amoxiclav - malangizo omwe angagwiritsidwe ntchito ndi akuluakulu

Mankhwala omwe amapezeka m'mapiritsi amatengedwa pakamwa ndi madzi ambiri. Ndi bwino kumeza piritsi musanadye. Chithandizo cha matendawa chimatha mpaka milungu iwiri popanda kufunsa dokotala.

Mapiritsi a Amoxiclav pa nthawi yapakati

Amoxiclav amatanthauza maantibayotiki amakono, omwe amachotsa matenda opatsirana ndi kutupa. Mankhwalawa ndi amodzi mwa otetezeka pakati pa mankhwala amphamvu a antibacterial. Chifukwa chake, Amoxiclav amaloledwa kwa amayi panthawi yapakati pamaso pamavuto akulu azaumoyo.

Pa nthawi ya pakati, mankhwalawa amatha kugwiritsidwa ntchito mu 2nd ndi 3 trimesters. Ndi bacteriuria asymptomatic, pofuna kupewa mavuto obwera chifukwa cha mimba, mankhwalawa amagwiritsidwa ntchito poyambira.

Amoxiclav chithandizo cha amayi apakati ndi choyenera ngati phindu kwa mayi woyembekezera ndilokwera kuposa zoyipa zomwe zingakhalepo pa mwana wosabadwayo.

Mlingo wa amayi apakati:
• 250-500 mg katatu patsiku,
• Ndi zovuta, mlingo umachulukitsidwa mpaka 625-875 mg katatu patsiku.
Kutalika kwa masiku ovomerezeka sikupitilira masiku 7.
Ngati mukuyamwitsa mwana, musiyeni pakumwa mankhwala ndi Amoxiclav. Maantibayotiki amadziunjikira mkaka ndipo amatha kupatsa ana:
• zotupa,
• kutsekula m'mimba,
• kutupa.

Mapiritsi a Amoxiclav 250 - malangizo omwe angagwiritsidwe ntchito ndi akuluakulu

Odwala akulangizidwa kugwiritsa ntchito makapisozi okhala ndi Mlingo wa 250 mg wa:
• kuwonongeka kwa ziwalo zopatsirana popanda zovuta, kapisozi imodzi katatu patsiku kwa masiku 5 mpaka 14,
• Matenda a odontogenic - piritsi limodzi katatu patsiku kwa masiku asanu (nthawi yayitali pakati pa Mlingo ndi maola osachepera 8). Kutalika kwa mankhwala osachepera masiku 5.
Imwani mankhwalawo ndi zakudya kuti mupewe zovuta zoyambira m'mimba.

Mapiritsi a Amoxiclav 500 - malangizo omwe angagwiritsidwe ntchito ndi akuluakulu

Mlingo wovomerezeka wa mapiritsi a 500 mg + 125 mg kwa akulu:
• kamodzi pa nthawi yodwala 2 kawiri pa tsiku ndikupumira kwa maola 12,
• Piritsi limodzi katatu patsiku, komanso nthawi yotalika maola asanu ndi atatu (8) pa matenda oyenda pang'ono komanso mwamphamvu.
• 1 kapisozi kawiri tsiku lililonse kwa masiku 10-14 pochizira matenda a prostatitis.
Pambuyo pakutha kwa zizindikiro zowoneka, mankhwala akupitiliza kwa masiku ena awiri.
Pafupifupi, chithandizo chimatenga masiku 5 mpaka 14.
Amoxiclav 500/125 mg sayenera kusinthidwa ndi makapisozi angapo ndi mulingo wotsika.

Mapiritsi a Amoxiclav 1000 - malangizo omwe angagwiritsidwe ntchito ndi akuluakulu

Kuchuluka kwatsiku ndi tsiku kwa clavulanic acid kwa akulu ndi 600 mg.
Amoxiclav 1000 mg amagwiritsidwa ntchito musanadye / mukatha kudya.

Yambani kuchira ndi theka la shuga.
Zotsatira zoyipa ngati mukumwa mankhwalawa.
• kusokonezeka kwa tulo,
• kutupa (mkamwa, nyini),
• zotupa pakhungu,
• mankhwala ochititsa chiwindi,
• cholestatic jaundice.

Mapiritsi a Amoxiclav - malangizo a ana

Ana osaposa zaka 6 ndi bwino kugwiritsa ntchito kuyimitsidwa, popeza mawonekedwe amadzimadzi:
• ndikosavuta kuti mwana atenge, sizimapangitsa kusanza.
• Ndi yabwino kusankha kumwa.

Mlingo umodzi umatengera zaka komanso kulemera kwa mwana. Mankhwalawa amatengedwa katatu patsiku.

Mapiritsi a Amoxiclav 250 - malangizo a ana

Mlingo wa 250 mg / 125 mg umaloledwa kwa ana azaka 12 zokha. Mapiritsi omwera ndi amoxiclav ndi oyenerera m'badwo uno, womwe uyenera kusungunuka mu 30-50 ml yamadzimadzi musanagwiritse ntchito. Imwani piritsi 1 katatu patsiku musanadye.
Mlingowu ukuwonetsedwa pofuna kuchiza matenda opezeka modekha pang'ono komanso modekha popanda zovuta. Njira yogwiritsira ntchito ndi masiku 5-7.

Mapiritsi a Amoxiclav 500 - malangizo a ana

Mapiritsi omwazikana amatha kupatsidwa kwa ana azaka 12, ngati unyinji wawo sunali wochepera 40 kilogalamu.
Tengani piritsi limodzi la 500 mg katatu patsiku mosiyanasiyana kwa masiku 7-14 pochiza matenda opumira komanso matenda omwe ali ndi zovuta:
• pachimake sinusitis, otitis media,
• Tillillitis,
• pachimake bronchitis,
• chibayo.

14 Mikhalidwe ndi moyo wa alumali

Mankhwalawa amasunga katundu wake pansi pa mawonekedwe a umphumphu wa chipolopolo, pamtunda wosaposa +25 ° C, kuchokera pakalibe dzuwa. Kutengera malamulo, moyo wa alumali ndi zaka 2 kuyambira tsiku lopangidwa.

Mankhwalawa amasunga katundu wake pansi pa mawonekedwe a umphumphu wa chipolopolo, pamtunda wosaposa +25 ° C, kuchokera pakalibe dzuwa.

Kodi pali kusiyana kotani pakati pa Amoxiclav ndi Amoxiclav 2x

Amoxiclav 2x ndi mtundu wabwinoko wa Amoxiclav wokhala ndi Mlingo wofotokozedwa ndi kafukufuku waposachedwa wasayansi. Kuwonjezeka kwa tsiku ndi tsiku mlingo komanso munthawi yomweyo kuchepetsa njira zamankhwala ndikulimbikitsa kwakukulu kwamankhwala amakono a antibayotiki.

Mlingo wowonjezera wa mankhwalawa ungachepetse kuchuluka kwa Mlingo patsiku, womwe ndi mwayi wabwino.

Mlingo wowerengera molondola wa clavulanic acid (125 mg) ndi wokwanira kuzipatsa zomwe zimafunikira pakapita kamodzi. Kupitilira izi ndizosatheka chifukwa cha kupezeka kwa mavuto.

Tamara, wazaka 27, Galich:

Pali zambiri pa matenda a angina omwe ali ndi antiotic. Mkhalidwe wa mwana wamkazi (wazaka 14) unali wokulirapo: kutentha kunachepera 40 ° C, samatha kudya kapena kulankhula, anali ndi zilonda zapakhosi. Dokotala anachenjeza kuti chithandizo chikuyenera kuchitidwa mwachangu kuti pasakhale zovuta m'mapapu kapena mumtima. Amoxiclav adayamba kuthandiza patsiku la 2, limodzi ndi ma rinses, inhalations komanso chakumwa chokoma. Atachira, adadutsa kuyesa kwa magazi ndi mkodzo, adotolo adati - zonse zili bwino.

Valentine, wazaka 50, Nizhny Novgorod:

Adatenga Amoxiclav ndi prexx ya 2x monga momwe adanenera katswiri wa ENT, mosamala pambuyo maola 12, piritsi limodzi. Matendawa adachiritsidwa, palibe zotsatira zoyipa, koma patatha milungu iwiri kuyezetsa magazi kunawonetsa kuti ma cellelo ndi ma cell oyera amachepetsa. Adotolo anatero atatelo mankhwalawo. Pambuyo pa masabata ena awiri, adamuyang'ananso - ziwonetsero zamagazi zabwerera mwakale. Osadzilimbitsa, ndipo ngati mukuyesa mayeso - onetsetsani kuti mukuyesa.

Leonid, dotolo wamano, ku Moscow:

Poyerekeza Amoxicillin ndi Amoxiclav, odwala nthawi yomweyo amalabadira kusiyana kwa mtengo. Yoyamba ndi yotsika mtengo, koma sindikuvomereza kupulumutsa. Clavulanate monga gawo la mankhwala atsopano amapangitsa kuti ikhale yothandiza kwambiri. Ndi mapiritsi amakono, chithandizo chokwanira chimatha kukhala ndi masiku 3-5, zonse zimatengera mtundu wa matenda. Ndipo kumwa mapiritsi 1 kapena 2 pa tsiku ndikosavuta.

Momwe mungachiritsire matenda a kwamkodzo ndi matenda a impso ndi Amoxiclav 2X?

Mtundu watsopano wamkamwa wophatikizidwa wakale wa amoxicillin ndi mankhwala a clavulanic acid wapangidwa chifukwa cha kafukufuku waposachedwa. Kugwiritsa ntchito mankhwala awiri pamodzi kunakulitsa kuchuluka kwa antibacterial kanthu, kunathandizira kuthana ndi kukana kwa tizilombo toyambitsa matenda ambiri. Atapezeka kuti kuphatikiza kwabwino kwambiri kwa zinthu zogwira ntchito komanso chitetezo cha mankhwala, mankhwala osakanikirana adapangidwa ndi mankhwala othandizira-clavulanate a 7: 1, motero.

Kodi 2x amatanthauza chiyani mdzina la mankhwalawa

Mankhwala ndi kuphatikiza kwa zinthu ziwiri zomwe zimagwirizana ndi zomwe wina akuchita. Zomwe zimapangidwira komanso kuchuluka kwa antioxotic (500 mg ndi 875 mg) ndizomwe zimayambitsa chiwonetsero mu dzinalo.

Fomu la mapiritsi linapangidwa kuti lithe kupulumutsira zovuta kwambiri komanso kupewa matenda opatsirana, malinga ndi kafukufuku waposachedwa pa luso la mankhwala othandizira.

Kutulutsa mafomu ndi kapangidwe kake

Mapiritsi a Amoxiclav ndi awa:

• amoxicillin - mankhwala a penicillin okhala ndi zochita zambiri za antibacterial,
• clavulanic acid - woletsa wa β - lactamase, kupewa kuwonongedwa kwa amoxicillin,
• zina zowonjezera pakatikati ndi zipolopolo za mapiritsi: colloidal silicon dioxide, magnesium stearate, cellulose, crospovidone, croscarmellose sodium, triethyl citrate, hydroxypropyl cellulose, polysorbate, titanium dioxide E171, talc.

Amoxicillin ndi clavulanate amaphatikizidwa ndi chiŵerengero cha 7: 1. Mankhwala amapezeka mu mawonekedwe a mapiritsi awiri Mlingo:

• 625 mg (500 mg + 125 mg),
• 1000 mg (875 mg + 125 mg).

Clavulanic acid ili mgulu lofanana (125 mg), wochepa mokwanira kuwonetsa ntchito zake zonse.

Mapiritsi ali ndi matuza a zojambulazo ndipo amaikidwa mu zidutswa 14 mumapaketi a makatoni okhala ndi malangizo ogwiritsira ntchito.

Mankhwala

Amoxiclav ali ndi mawonekedwe owonjezereka ochitapo kanthu. Mankhwalawa amagwira ntchito yolimbana ndi tizilombo toyambitsa matenda tokhala ndi amoxicillin, komanso ma bacteria omwe amalimbana ndi penicillin chifukwa chopanga ma beta-lactamases: gram-negative and gram-aerobes, anaerobes, spirochetes.

Clavulanic acid imamanga mabakiteriya oteteza mabakiteriya, amapanga minyewa yolimba, yomwe imakhala yogwira mwachilengedwe ndipo imatuluka mwachangu mthupi. Izi zimathandizira kuti maantibayotiki awonetse antimicrobial katundu wake ndikuwononga mabakiteriya oyipa, ndikuwononga khoma lawo.

Kuchuluka kwa amoxicillin kumakupatsani mwayi wothana ndi pneumococci ambiri, omwe ma penicillin ena alibe mphamvu.

Kuwonjezeka kwa mlingo wa tsiku ndi tsiku kwinaku akumachepetsa nthawi yamankhwala ndikofala masiku ano.

Kuchepetsa kuchuluka kwa clavulanate (poyerekeza ndi mankhwala osakanikirana kale) kumathandizira kulolerana kwa mankhwalawo ndikusungabe zochitika zokwanira kuti musayambitsa β-lactamases.

Pharmacokinetics

Magawo a zinthu ziwiri zomwezi amagwiranso ntchito muzochita zamankhwala ndi bioavailability. Onsewa amatengeka kwambiri m'mimba. The bioavailability wa clavulanate ndi oposa 60%, mu amoxicillin amafika 95%. Pazinthu zochizira, zinthu zimapezeka m'matumbo amisempha, mbali zonse za bronchopulmonary system (kuphatikizapo bronchial secretion ndi madzi a pleural), ziwalo za ENT (khutu lapakati, matoni), zotumphukira ndi zotumphukira, ma genitourinary system, ndi ziwalo za pelvic.

Zinthu zodutsa chotchinga, mu mkaka wa m'mawere mumapezeka zochuluka. Amalowetsa chingwe cha msana posakhazikika bwino ndipo sagwira ntchito ndi meningitis. Amamangiriza mapuloteni amwazi pafupifupi 20% mpaka 30% ya chinthucho.

Chiyero chochepetsetsa kwambiri cha matenda chimagwira pafupifupi 40% ya nthawi yayitali pakati pa Mlingo, pokhapokha ngati imagwiritsidwa ntchito kawiri pa tsiku limodzi ndi nthawi yomweyo. Hafu ya moyo wa amoxicillin wokhala ndi clavulanic acid amakhala pafupifupi maola 1.5. Mankhwalawa amachotseredwa ndi impso osasinthika, clavulanate amapezeka mu chiwindi, ndipo ambiri amasiya thupi mthupi.

Kodi mapiritsi a amooticlav 2x amachokera kuti

Amoxiclav zotchulidwa matenda a bakiteriya:

• matenda amtunduwu
• sinusitis (nthawi yayitali komanso yovuta),
• kuwonongeka pakhungu ndi minofu yofewa, kuphatikiza zilonda za septic, kuluma, purifiyamu ndi sepsis,
• zotupa mu mkamwa ndi maxillofacial dera,
• matenda a minofu, mafupa a mafupa ndi mafupa,
• chanchlon, chinzonono,
• mitundu yosiyanasiyana ya matenda oyambitsidwa ndi anaerobic ndi ma tizilombo toyambitsa matenda aerobic.

Mankhwala ndi othandiza mankhwalawa bile ducts, ENT ziwalo, abscesses osiyanasiyana kutulutsa. Njira ya mankhwalawa imagwiritsidwa ntchito popewa matenda opatsirana pambuyo pake.

Momwe mungatenge Amoxiclav 2x

Pokhala ndi kuchuluka kowonjezera, mapiritsiwo ndi okulirapo. Sizovomerezeka kugawa magawo, kutafuna kapena kuphwanya umphumphu wa chipolopolo. Mapiritsiwo amameza lonse ndi madzi ambiri (osachepera 200 ml).

Ndi njira ya chithandizo, kuchuluka kwa madzimadzi oledzera sikuyenera kukhala ochepera 2 malita patsiku.Popewa dysbiosis, ma probiotic amapatsidwa limodzi.

Kuchepetsa zovuta zoyipa kuchokera m'matumbo am'mimba komanso kupewa kutulutsa kwa pseudomembranous colitis, mankhwalawa amatengedwa kumayambiriro kwa chakudya.

Mlingo wa tsiku ndi tsiku komanso chithandizo cha mankhwalawa zimayikidwa payekhapayekha ndipo zimatengera kuopsa kwa matendawa komanso momwe thupi limayankhira pomvera. Wokhazikika, 1 g ya mankhwalawa imapangidwa (fomu 875/125) maola 12 aliwonse. Kutalika kwa chithandizo kumatha kusintha kuchokera masiku 5 mpaka milungu iwiri.

Pofuna kupewa zovuta pa ntchito

Fomu ya Mlingo imagwiritsidwa ntchito kwambiri pakuchita opareshoni: mu mano ndi zodzikongoletsera, komanso pakugwira ntchito pamimba. Pofuna kupewa matenda opatsirana pambuyo polowera ziwalo zam'mimba, mafupa am'mimba, ndulu ya mtima, ndi mtima dongosolo, masiku 5 a mankhwalawa amagwiritsidwa ntchito. Mlingo wa tsiku ndi tsiku umatsimikiziridwa ndi dokotala potengera zomwe akuwonetsa.

Amoxiclav imaphatikizidwa pamndandanda wamankhwala a odwala omwe akuwonjezera impso, corteryary artery bypass grafting, kuphatikizidwa kwa valavu yamtima.

Matenda a kwamkodzo thirakiti

Kuthekera kwa mankhwalawa kupanga mapangidwe azinthu zambiri mu genitourinary system imagwiritsidwa ntchito pochiza matenda a pyelonephritis, cystitis, ndi urethritis wa bakiteriya. Kutalika kwa mankhwala kumatsimikiziridwa ndi adokotala, kutengera mtundu womwe wapezeka, atha kuyambira masiku 5 mpaka 14.

Mitundu yosakanikirana yamatenda imayendera bwino pochiza ndi mankhwala ophatikiza, osafuna chithandizo chamankhwala osiyanasiyana. Mankhwalawa ali ndi nephrotoxicity yocheperako ndipo amafulumira kuthira mkodzo, amakupatsani mwayi kuti muchotse mabakiteriya okhala ndi matenda a genitourinary system.

Pa mimba ndi mkaka wa m`mawere

M'maphunziro a nyama, palibe zoyipa zochokera kugwiritsidwa ntchito kwa mankhwalawa panthawi yomwe muli ndi pakati, zotsatira za kubala kwa mwana kapena kubereka kwakatulutsidwa.

Chifukwa cha kuchuluka kwa mankhwalawa ophatikiza mankhwala ophatikizira pakati pa nthawi yomwe ali ndi pakati, mankhwalawa amatha kuthandizidwa molingana ndi zofunikira pokhapokha pakufunika, ndipo pokhapokha ngati phindu la chithandizo likupita patsogolo kwa thanzi la mayi ndi mwana wosabadwayo.

Zinthu zonse ziwirizi zimapita mkaka wa m'mawere. Kukhazikika kwa mankhwala pa nthawi yoyamwitsa kungayambitse matenda am'mimba komanso fungal matenda a mucous nembanemba a mwana. Mwina chitukuko cha thupi lawo siligwirizana. Pakakhala mawonekedwe a zisonyezo, kuyamwitsa kuyimitsidwa kwakanthawi.

Mankhwala amaloledwa kugwiritsidwa ntchito pa mkaka wa kuyang'aniridwa ndi achipatala, atawunika kuchuluka kwa mapindu ake ndi chiopsezo.

Ndi mkhutu aimpso ntchito

Amoxiclav mwanjira imeneyi sagwiritsidwa ntchito pochiza matenda ngati, malinga ndi zotsatira za kafukufuku, mtundu wa clearinine chilolezo chotsika 30 ml / min. Pakakhala vuto losakwanira la impso, kusintha kwa mankhwalawa komanso kuwonjezeka kwakatikati pakati Mlingo zofunika. Chifukwa chake, mankhwalawa nthawi zambiri amasinthidwa ndi analogi ndi mlingo wotsika.

Ngati ndi kotheka, amoxiclav / clavulanate 1000 mg (875/125 mg) akhoza kutumizidwa chifukwa cha kupweteka kwambiri kwa aimpso mu piritsi limodzi patsiku. Ndi anuria, nthawi yapakati pakati Mlingo wa mankhwalawa imakulitsidwa mpaka masiku awiri kapena kuposerapo.

Ndi chiwindi ntchito

Zotsatira zoyipa za chiwindi zimapezeka ndi maphunziro a nthawi yayitali. Nthawi zambiri, zamatsenga zimadziwika mwa amuna okulirapo kuposa zaka zapakati. Mwa akazi, zotupa ndizosowa.

Ndi kulephera kwa chiwindi, chithandizo chimayikidwa mosamala, kuwunika ntchito ya chiwindi nthawi zonse.

AMOKSIKLAV

• Zizindikiro zogwiritsidwa ntchito
• Njira yogwiritsira ntchito
• Zotsatira zoyipa
• Contraindication
• Mimba
• Kuchita ndi mankhwala ena
• Bongo
• Kutulutsa Fomu
• Malo osungira
• Kupanga
• Zosankha

Amoxiclav - antibacterial kuphatikiza mankhwala. Zosakaniza zogwira ntchito: amoxicillin - mankhwala a penicillin gulu lochita zinthu zingapo komanso beta-lactamase inhibitor wa tizilombo - clavulanic acid.Clavulanic acid imalepheretsa kuwonongeka kwa amoxicillin chifukwa cha mapangidwe okhazikika a malo okhala ndi beta-lactamases: mwanjira iyi, maofesi omwe amapangidwa ndi osagwira komanso osasunthika.

Amoxicillin imagwira ntchito motsutsana ndi mabakiteriya omwe amamva nayo. Chifukwa chophatikizidwa ndi beta-lactamase inhibitor (clavulanic acid) mu mankhwalawa, mankhwalawa amatha kuperekedwanso matenda opatsirana ndi amoxicillin. Amoxicillin osakanikirana ndi clavulanic acid amagwira ntchito motsutsana: Streptococcus pneumonia, Str. bovis, Str. pyogene, Listeria spp., Staphylococcus aureus, S. epidermidis, Enterococcus spp. . ., Peptococcus spp., Clostridium spp., Actinomyces israelii, Peptostreptococcus spp.).

Mwambiri, magawo a pharmacokinetic a clavulanic acid ndi amoxicillin ndi ofanana akamagwiritsidwa ntchito palimodzi, chifukwa chake, alibe mphamvu pamagulu a zinthu zamtundu wa pharmacokinetic. Pambuyo pa kayendetsedwe ka mkati, zonse ziwiri zimaphatikizidwa bwino. Kuzama kwa plasma kwakukulu kumafikiridwa patatha pafupifupi mphindi 60. Kugwiritsa Amoxiclava Ndi chakudya sizikhudza mayamwidwe a clavulanic acid ndi amoxicillin. Hafu ya moyo wa clavulanic acid ndi mphindi 60-70, kwa amoxicillin - mphindi 78. Zonsezi zimalowa mkati mwa minyewa ndi manyuzipepala amadzimadzi mosavuta, makamaka kudziunjikira zobisika zamkati zam'mapapo, mapapo, mkati mwa khutu, mkati mwazinthu zam'mimba komanso zotulutsa za m'mimba, mazira ndi chiberekero. Pamene meningitis Amoxiclava kudutsa chotchinga magazi-chotchinga. Zimalowa mkatikati mwa chotchinga ndipo zimatsimikiziridwa mu kuchuluka kwa mkaka wamawere.

Ndi bolus makonzedwe Amoxiclava pa mlingo wa 1,2 g, kuchuluka kwakukulu kwa plasma ya clavulanic acid kumawonedwa pa 28,5 mg / l, amoxicillin - 105.4 mg / ml. Pambuyo mphindi 60, kuchuluka kwakukulu kwa zinthu izi mumadzi amthupi kumatsimikizika. Clavulanic acid ndi amoxicillin onse amapanga mapuloteni a plasma, motero, mwa 22-30% ndi 1720%.

Clavulanic acid imakhala ndi kagayidwe kakakulu mu minyewa ya chiwindi. Imapukusidwa pang'ono ndi mpweya komanso ndowe zomwe zatha, makamaka impso. Amoxicillin amapukusidwa osasinthika mkodzo.

Kutulutsa Fomu

Mapiritsi a Amoxiclav - 250 mg ya amoxicillin / 125 mg wa clavulanic acid, wolemba-filimu, phukusi - 15 zidutswa.

Mapiritsi a Amoxiclav 2X - 500 mg / 125 mg, 875 mg / 125 mg, filimu yokutira, (phukusi - zidutswa 10 kapena 14).

Amoxiclav pakamwa kuyimitsidwa - 312,5 mg / 5 ml (250 mg ya amoxicillin pa 5 ml ya kuyimitsidwa / 62,5 mg wa clavulanic acid pa 5 ml ya kuyimitsidwa), 156.25 mg / 5 ml (125 mg wa amoxicillin 5 ml ya kuyimitsidwa / 31.25 mg wa clavulanic acid pa 5 ml ya kuyimitsidwa) - botolo lokonzekera 100 ml ya kuyimitsidwa, phukusi - 1 botolo.

Amoxiclav kwa makina a makolo - ufa wokonzekera njira yothetsera utsi m'mitsempha ya 600 mg mu botolo (500 mg ya amoxicillin ndi 100 mg wa clavulanic acid) kapena 1.2 g mu botolo (1000 mg ya amoxicillin ndi 200 mg wa clavulanic acid) .

Malo osungira

Mapiritsi a Amoxiclav 250 mg / 125 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 250 mg, clavulanic acid) mu mawonekedwe a potaziyamu mchere 500 mg.
Zinthu zosagwira: microcrystalline cellulose, sodium croscarmellose.

Amoxiclav 156.25 mg / 5 ml kuyimitsidwa ufa
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 125 mg / 5 ml, clavulanic acid) mu mawonekedwe a mchere wa potaziyamu 31.25 mg / 5 ml.
Zinthu zopanda ntchito: sodium citrate, cellcrystalline cellulose, sodium benzoate, sodium saccharin, mannitol.

Ufa wa kuyimitsidwa Amoxiclav 312,5 mg / 5 ml
Zinthu zomwe zimagwira ntchito: amoxicillin (mwa mawonekedwe a trihydrate) 250 mg / 5 ml, clavulanic acid) monga potaziyamu 62,5 mg / 5 ml.
Zinthu zopanda ntchito: sodium citrate, cellcrystalline cellulose, sodium benzoate, sodium saccharin, mannitol.

Ufa wa kulowetsedwa kulowetsedwa Amoxiclav 600 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a mchere wa sodium) 500 mg, clavulanic acid) monga potaziyamu 100 mg.

Ufa wa kulowetsedwa kulowetsedwa Amoxiclav 1200 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a mchere wa sodium) 1000 mg, clavulanic acid) monga potaziyamu 200 mg.

Mapiritsi a Amoxiclav 2X 500 mg / 125 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 500 mg, clavulanic acid) mu mawonekedwe a potaziyamu mchere 125 mg.
Zinthu zopanda ntchito: anhydrous colloidal silicon dioxide, aspartame, kununkhira kwa lalanje, kusakaniza kwa malo otentha, yellow iron oxide (E172), hydrogenated castor mafuta, talc, microcrystalline cellulose silrate.

Mapiritsi a Amoxiclav 2X 875 mg / 125 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 875 mg, clavulanic acid) monga potaziyamu mchere wa 125 mg.
Zinthu zopanda ntchito: anhydrous colloidal silicon dioxide, aspartame, kununkhira kwa lalanje, kusakaniza kwa malo otentha, yellow iron oxide (E172), hydrogenated castor mafuta, talc, microcrystalline cellulose silrate.

Amoxiclav Quicktab mapiritsi 500 mg / 125 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 500 mg, clavulanic acid) mu mawonekedwe a potaziyamu mchere 125 mg.
Zinthu zopanda ntchito: anhydrous colloidal silicon dioxide, aspartame, kununkhira kwa lalanje, kusakaniza kwa malo otentha, yellow iron oxide (E172), hydrogenated castor mafuta, talc, microcrystalline cellulose silrate.

Mapiritsi a Amoxiclav Quicktab 875 mg / 125 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 875 mg, clavulanic acid) monga potaziyamu mchere wa 125 mg.
Zinthu zopanda ntchito: anhydrous colloidal silicon dioxide, aspartame, kununkhira kwa lalanje, kusakaniza kwa malo otentha, yellow iron oxide (E172), hydrogenated castor mafuta, talc, microcrystalline cellulose silrate.

Zosankha

Ndi chisamaliro Amoxiclav zotchulidwa kwa odwala omwe amawonetsa mayankho am'mbuyomu. Pali kuthekera kwa kuyanjana pakati pa ma penicillin ndi mankhwala a cephalosporin, motero, mosamala Amoxiclav omwe ali ndi matupi awo sagwirizana ndi cephalosporins.
Pa vuto la chiwindi, kuwunika kwa mayesero a chiwindi ndikofunikira.

Mu 95% ya odwala khansa ya m'mimba ndi matenda a mononucleosis Amoxiclava limodzi ndi chitukuko cha zotupa pakhungu, odwala oterewa saloledwa kugwiritsa ntchito mankhwalawa.
Odwala omwe ali ndi vuto lowonongeka la impso, mlingo umasankhidwa payekha, kuwonjezeka kwakanthawi pakati pamajekeseni a mankhwala amaloledwa.

Mukamachitira mankhwala, tikulimbikitsidwa kugwiritsa ntchito madzi ambiri kapena madzi ena.
Amoxiclav imadzetsa zabodza pazotsatira za Coombs ndi kuyesedwa kwa Benedict (kudziwa kuchuluka kwa shuga mumkodzo). Chifukwa chake, tikulimbikitsidwa kugwiritsa ntchito mayeso a shuga, omwe amachokera pa enzymatic oxidation reaction.

Mapiritsi a Amoxiclav - malangizo a boma ogwiritsira ntchito

MALANGIZO
pa kugwiritsa ntchito mankhwalawa
ntchito zamankhwala

Werengani malangizo awa mosamala musanayambe kumwa / kugwiritsa ntchito mankhwalawa.
Sungani bukuli, lingafunenso.
• Ngati muli ndi mafunso, funsani dokotala.
• Mankhwalawa amaperekedwa kwa inu panokha ndipo sayenera kugawana ndi ena, popeza amathanso kuwavulaza ngakhale mutakhala ndi zofanana ndi inu.

Nambala yolembetsa

Nambala yolembetsa ku Russian Federation - П N012124 / 01.

2 Mawonekedwe ake ndi mitundu

Mapiritsi okhathamira othandiza kuti asungunuke pakamwa amapangidwira pakamwa ndipo amapezeka mu mitundu iwiri:

• 500 mg + 125 mg, kwathunthu - 625 mg, osankhidwa 500/125,
• 875 mg + 125 mg, ponseponse - 1000 mg (875/125).

Mapiritsi okhala ndi zotumphukira amapezeka mu Mlingo wa 875 mg + 125 mg.

Zowonjezera pazomwe zimapangidwira phukusi la piritsi ndi chipolopolo: silicon dioxide, polysorbate, magnesium stearate, crospovidone, croscarmellose sodium, triethyl citrate, hydroxypropyl cellulose, titanium dioxide (E171), talc, MCC.

3 Gulu la mankhwala

Gulu la Clinical ndi pharmacological: mankhwala opanga ma cell angapo opanga ma cellic angapo osakanikirana ndi penicillin osakanikirana ndi β-lactamase inhibitor.

4 Mankhwala

Clavulanic acid ndi mankhwala ofooka ofooka ndipo mwanjira yofanana ndi gulu la beta-lactam. Udindo wake pakukonzekera kophatikiza ndikuteteza amoxicillin kuti asawonongeke.

Ma Enzymes opangidwa ndi mabakiteriya ena (beta-lactamases) amateteza tizilombo toyambitsa matenda ku maantibayotiki. Chifukwa chake, pali zovuta zophatikiza ndi mankhwala.

Clavulanate amathetsa vutoli poletsa mabakiteriya omwe amatsutsa - kumanga β-lactamases ndikuwachotsa m'thupi. Zotsatira zosiyanasiyana za amoxicillin zimawonjezeka chifukwa chogwiritsidwa ntchito munthawi yomweyo ndi inhibitor.

Magulu a mabakiteriya otsatirawa ali ndi chidwi chotsatira chakukonzekera kwazinthu ziwiri:

• gram-aerobes wabwino (streptococci, listeria, enterococci, ena staphylococci),
• gram-negative aerobes (Haemophilus influenzae, Gardnerella vaginalis, Salmonella spp., Shigella spp., Helicobacter pylori, Brucella spp, Pasteurella multocida, Proteus spp. ndi ena),
• tizilombo toyambitsa matenda a anaerobic gram-positive (Clostridium spp., Peptococcus spp., Peptostreptococcus spp., Clostridium spp., Fusobacterium spp., Prevotella spp.),
• Gram-hasi anaerobic okhala ndi ndodo yowumbidwa ndi ndimu (Bacteroides spp., Fusobacterium spp.).

Mphamvu yotsutsa ya amoxicillin imayamba chifukwa chophwanya kukhulupirika kwa nembanemba wa bakiteriya ndi kuyamwa kwa maselo a pathogen. Amaloŵereratu msanga m'mimba, ngakhale zakudya, zakudya zamafuta zimalowa m'matupi athu onse komanso zakumwa zamthupi. Kuzindikira kwakukulu kumawonedwa mphindi 60 kuchokera pakamwa.

Zinthu zonsezi zimapangidwa makamaka ndi impso: amoxicillin osasinthika, clavulanate mu mawonekedwe a metabolites opangidwa m'chiwindi.

5 Zomwe zimathandiza Amoxiclav 2x

Kuchuluka kwa amoxicillin piritsi limodzi la mankhwalawa amapangidwira kuti azigwiritsidwa ntchito mozama: ndi matenda owopsa, zotupa zosakhalitsa, kupezeka kwa tizilombo toyambitsa matenda angapo kapena chifukwa chosatitsimikizira.

Mankhwala omwe akufunsidwa amapatsidwa bronchitis.

Fotokozani mankhwala a bakiteriya omwe amayamba ndi machitidwe ndi ziwalo:

• mbali zam'munsi za broncho-pulmonary system: tonsillitis, chibayo, bronchitis, pleurisy,
• Ziwalo za ENT: sinusitis, atitis media, pharyngeal abscess,
• m`kamwa ndi maxillofacial dera: periodontitis, pulpitis, maxillary phlegmon,
• genitourinary system: kwamikodzo thirakiti, matenda am'mimba, matenda amkodzo, kuphatikizapo chinzonono, chancre,
• minofu yofewa ndi khungu: kutupa kwatsuka, mabala opatsirana, furunculosis,
• minofu: mafupa a m'mafupa ndi mafupa,
• matenda osakanikirana a biliary thirakiti, mtima dongosolo, abscesses osiyanasiyana kutulutsa.

Amoxiclav imagwiritsidwa ntchito popewa matenda opatsirana pambuyo pachitetezo cha opaleshoni yam'mimba, pelvis yaying'ono, mtima, mafupa, opaleshoni ya maxillofacial ndi mano.

6 Momwe mungatenge Amoxiclav 2x

Piritsi lamakono lamankhwala omwe amapezeka ndi kuchuluka kwa mankhwalawa amangolembedwa kwa odwala akuluakulu (azaka zopitilira 12) okhala ndi thupi loposa 40 kg. Zochizira ana, othandizira apadera amapangidwa m'njira yoyimitsa pakamwa. Ufa wokonza njira yothetsera vutoli umapezeka mosavuta kutengera kulemera kwa mwana, Dokotala wa ana amawerenga kuchuluka kwa zinthuzo.

Amoxiclav (1000 mg) yopuma komanso matenda ena owopsa amapatsidwa piritsi 1 lililonse maola 12.

Amoxiclav (1000 mg) yopuma komanso matenda ena owopsa amapatsidwa piritsi 1 lililonse maola 12. Pa mlingo wofanana ndi 500 mg wa antibayotiki, mankhwalawa amatengedwa maola 8 aliwonse.

M'mikhalidwe ya zolimbitsa kukula kapena kuwonongeka kwa chapamwamba kupuma thirakiti (sinusitis, sinusitis, tonsillitis), amoxiclav 500/125 katatu patsiku ndi zofanana magawo.

Mukamapereka mapiritsi a 875/125, sizovomerezeka kuti amangosintha mwachisawawa mapiritsi ena ochepa.

Mlingo wambiri wa clavulanic acid umachulukitsa matenda.

Njira ya mankhwala ophatikiza ndi antioxotic ndi kuyambira masiku 5 mpaka 7 ndipo imangowonjezeredwa pokhapokha ngati dokotala akuwalimbikitsa. Mulingo wovomerezeka wa mankhwala omwe amatengedwa patsiku sayenera kupitirira 6 g malinga ndi amoxicillin.

Malangizo apadera

Mlingo wa kuthetsedwa kwa mankhwala ophatikiza umatsika molingana ndi kuchepa kwa impso. Pamene creatinine chilolezo chimakhala chochepera 10 ml / min, kukonza kwa nthawi imodzi kumachitika kapena kupangika kwapakati.

Kulephera kwakukulu kwa aimpso, piritsi limodzi (1 g) la mankhwalawa limatengedwa maola 24 aliwonse.

Kulephera kwakukulu kwa aimpso, kuthetseratu theka la moyo wa amoxicillin kumachepetsa mpaka maola 7-8. Zikatero, piritsi limodzi (1 g) limatengedwa maola 24 aliwonse, moyang'aniridwa ndi dokotala. Kwa odwala ochepetsedwa diuresis, nthawi yapakati pakati Mlingo imatha kuchuluka kwa masiku awiri.

Popereka mankhwala ochuluka a amoxicillin, odwala omwe ali ndi makodzo osakanikirana a mkodzo amayenera kuwunika kuchuluka kwa catheter. Mankhwala amakhala ndi katundu wokhazikika pamakoma ndikuchepetsa kutulutsa madzi.

Zotsatira zoyipa za Amoxiclav 2x

Kuphatikiza kwa zinthu zomwe zimagwiritsidwa ntchito mosiyanasiyana, zoyesedwa mwachipatala, zimalekeredwa bwino ndi odwala. Zotsatira zoyipa ndizosowa. Madandaulo am'mimba (mu 9% ya odwala), nseru ndi zotupa pakhungu (3%), ndikusanza adadziwika mu 1% ya milandu yonse.

Chiwerengero cha yogwira pophika mankhwala 7: 1 chimachepetsa kuchuluka kwa zoyipa ndi theka poyerekeza ndi mitundu yomwe imatengedwa pafupipafupi 2 pa tsiku.

Mwa zotheka zosatheka ndi mankhwalawa, amanenanso: kupweteka mutu, kutupa, impso ndi chiwindi, matupi awo owonetsa zovuta.

Zotsatira zoyipa zingasonyeze kusalolera kwa mankhwalawo kapena mankhwala osokoneza bongo. Kukhazikika kwa matendawa kumafunikira kuyezetsa kuchipatala msanga kuti musinthe mankhwalawo m'malo mwake.

Prem Amoxiclav 2x imatha kupweteketsa mutu.

Kutalika kwa nthawi yayitali kumatha kutsatiridwa ndi kuphwanya matumbo ndi microflora yamatumbo, kukula kwa mphamvu, kuphatikizirana kwa nephritis, hematuria, crystalluria.

Kukopa pa kuyendetsa galimoto ndi njira zina

Panalibe zotsatirapo zoipa za kuchuluka kwa chidwi ndi zochita kuchokera ku Amoxiclav. Kusiyana kwake kumachitika pamene mankhwalawo amagwiritsidwa ntchito koyamba ndipo zotsatira zoyipa za thupi sizitsatira.

9 Kutsutsana

Mgwirizano wotsutsana kwathunthu ku Amoxiclav ndi mlingo wowonjezereka ndi zinthu:

• matenda mononucleosis,
• Mavuto a chiwindi omwe amadalira antioxotic, cholestatic jaundice,
• omwe kale anali osagwirizana ndi mankhwala a beta-lactam (kuphatikiza penicillin ndi cephalosporins),
• lymphocytic leukemia.

Pa nthawi yoyembekezera komanso mkaka wa m`mawere, mawonekedwe a piritsi amatha kuperekedwa pokhapokha akuwonetsa mosamala. Odwala omwe ali ndi mbiri ya pseudomembranous colitis amawalandira mosamala.

Kutsutsana kotheratu pakusankhidwa kwa Amoxiclav ndiko kuwonongeka kwa chiwindi komwe kumadalira mankhwala.

10 Mankhwala osokoneza bongo

Mankhwala osokoneza bongo amatha kuyambitsa chithandizo chambiri, kupitirira Mlingo woyenera kapena kuwonongeka kwa chinthu m'thupi. Zizindikiro za mankhwala owonjezera amatha kukhala osagwirizana (kuyambira pachiwopsezo mpaka pakhungu), kupweteka mutu, kukokana (kawirikawiri), nkhawa, komanso kusowa tulo.

Palibe mankhwala enieni; chithandizo ndichizindikiro. Ndi chizindikiro chodziwika bwino cha mankhwala osokoneza bongo, muyenera kuyitanitsa dokotala, kutsuka m'mimba mwanu ndi kutenga enterosorbents. Woopsa milandu, hemodialysis akhoza kuwonetsedwa. Milandu yamankhwala osokoneza bongo opezeka ndi zakupha sizinalembedwe.

11 Kuchita Zinthu Mosagwirizana

Kugwiritsa ntchito munthawi yomweyo mankhwala ndi Amoxiclav kumatheka pokhapokha pakugwirizana ndi adokotala. Amoxiclav imatha kudutsa pamtanda ndi zinthu zamagulu osiyanasiyana.

Zotsatira zina

• Kuchuluka kwa kawopsedwe ndi methotrexate.
• Kuchepetsa mayamwidwe ndi mankhwala ofewetsa tuvi tolimba, aminoglycosides, ma antacid.
• Kulimbikitsa machitidwe a anticoagulants akaphatikizidwa palimodzi.
• Kuchepetsa mphamvu ndi ma tetracyclines, macrolides, sulfonamides.
• Kuchulukitsa kwa ma antioxotic ndi zinthu zomwe zimalepheretsa katulutsidwe ka tubular.
• The kuchuluka kwa immunosuppressants (makamaka, mycophenolate mofetil) amachepetsa mu odwala omwe akupatsidwa chiwalo ndi minofu kupatsirana.
• Mphamvu ya njira zakulera zam'kamwa zimachepetsedwa.

Kutenga Amoxiclav 2x kungachepetse mphamvu ya njira zakulera zamkamwa.

Amoxiclav sagwiritsidwa ntchito limodzi ndi disulfiram, allopurinol, rifampicin.

Mothandizidwa ndi ascorbic acid imathandizira kuyamwa kwa maantibayotiki m'mimba.

Ndi mowa

Amoxiclav osakanikirana ndi mowa amachititsa antabuse, momwe mawonekedwe owopsa onse a mankhwala ndi mowa amachuluka. Kugwiritsa ntchito kwa antibayotiki pakulimbana ndi matenda kumachepetsedwa kwambiri, ndipo zotsatira zoyipa zamafayidwe amthupi (chiwindi, impso) zikuchulukirachulukira.

• nseru, kutsegula m'mimba, kusanza,
• kuthamanga kwa magazi pankhope, khungu rede, chizungulire,
• kupuma pang'ono mpaka kugwedezeka kwa anaphylactic,
• dontho lakuthwa la kuthamanga kwa magazi, tachycardia, bradycardia.

Intoxication imatha kuchitika nthawi yomweyo kapena kuchedwa. Zomwe zimachitika pakamwa mowa wophatikizana ndi Amoxiclav sizikudziwika ndipo sizodalira mphamvu kapena mtundu wa chinthu chomwe chili ndi mowa.

Kugwiritsa ntchito Amoxiclav 2x ndi mowa kumatha kuyambitsa kusanza.

Wopanga

Mankhwala oyamba amapangidwa ku Slovenia, patent ndi ya kampani ya mankhwala Lek (Lek Pharmaceuticals d. D.).

13 Mikhalidwe yakusiya mankhwala

Amoxiclav amatanthauza mankhwala omwe mumalandira komanso mufunika mankhwala omwe mumalandira.

Mtengo wa mankhwala oyambira omwe ali ndi Mlingo wa 500/25 mg m'mapiritsi osiyanasiyana amakhala kuzungulira ma ruble 400. Mtengo wa Amoxiclav 875/125 umayamba pa 420 rubles.

14 Mikhalidwe ndi moyo wa alumali

Mankhwalawa amasunga katundu wake pansi pa mawonekedwe a umphumphu wa chipolopolo, pamtunda wosaposa +25 ° C, kuchokera pakalibe dzuwa. Kutengera malamulo, moyo wa alumali ndi zaka 2 kuyambira tsiku lopangidwa.

Mankhwalawa amasunga katundu wake pansi pa mawonekedwe a umphumphu wa chipolopolo, pamtunda wosaposa +25 ° C, kuchokera pakalibe dzuwa.

15 Analogi

Malinga ndi gulu la pharmacological, ma analogues (ma syonyms) a amooticlav ndi mankhwala otere:

• Amoxil
• Augmentin
• Foraclav
• Flemoklav Solutab,
• Panclave
• Samalirani
• Mochulukitsa
• Ecobol.

Kodi pali kusiyana kotani pakati pa Amoxiclav ndi Amoxiclav 2x

Amoxiclav 2x ndi mtundu wabwinoko wa Amoxiclav wokhala ndi Mlingo wofotokozedwa ndi kafukufuku waposachedwa wasayansi. Kuwonjezeka kwa tsiku ndi tsiku mlingo komanso munthawi yomweyo kuchepetsa njira zamankhwala ndikulimbikitsa kwakukulu kwamankhwala amakono a antibayotiki.

Mlingo wowonjezera wa mankhwalawa ungachepetse kuchuluka kwa Mlingo patsiku, womwe ndi mwayi wabwino.

Mlingo wowerengera molondola wa clavulanic acid (125 mg) ndi wokwanira kuzipatsa zomwe zimafunikira pakapita kamodzi. Kupitilira izi ndizosatheka chifukwa cha kupezeka kwa mavuto.

Tamara, wazaka 27, Galich:

Pali zambiri pa matenda a angina omwe ali ndi antiotic. Mkhalidwe wa mwana wamkazi (wazaka 14) unali wokulirapo: kutentha kunachepera 40 ° C, samatha kudya kapena kulankhula, anali ndi zilonda zapakhosi. Dokotala anachenjeza kuti chithandizo chikuyenera kuchitidwa mwachangu kuti pasakhale zovuta m'mapapu kapena mumtima. Amoxiclav adayamba kuthandiza patsiku la 2, limodzi ndi ma rinses, inhalations komanso chakumwa chokoma. Atachira, adadutsa kuyesa kwa magazi ndi mkodzo, adotolo adati - zonse zili bwino.

Valentine, wazaka 50, Nizhny Novgorod:

Adatenga Amoxiclav ndi prexx ya 2x monga momwe adanenera katswiri wa ENT, mosamala pambuyo maola 12, piritsi limodzi.Matendawa adachiritsidwa, palibe zotsatira zoyipa, koma patatha milungu iwiri kuyezetsa magazi kunawonetsa kuti ma cellelo ndi ma cell oyera amachepetsa. Adotolo anatero atatelo mankhwalawo. Pambuyo pa masabata ena awiri, adamuyang'ananso - ziwonetsero zamagazi zabwerera mwakale. Osadzilimbitsa, ndipo ngati mukuyesa mayeso - onetsetsani kuti mukuyesa.

Leonid, dotolo wamano, ku Moscow:

Poyerekeza Amoxicillin ndi Amoxiclav, odwala nthawi yomweyo amalabadira kusiyana kwa mtengo. Yoyamba ndi yotsika mtengo, koma sindikuvomereza kupulumutsa. Clavulanate monga gawo la mankhwala atsopano amapangitsa kuti ikhale yothandiza kwambiri. Ndi mapiritsi amakono, chithandizo chokwanira chimatha kukhala ndi masiku 3-5, zonse zimatengera mtundu wa matenda. Ndipo kumwa mapiritsi 1 kapena 2 pa tsiku ndikosavuta.

Momwe mungachiritsire matenda a kwamkodzo ndi matenda a impso ndi Amoxiclav 2X?

Mtundu watsopano wamkamwa wophatikizidwa wakale wa amoxicillin ndi mankhwala a clavulanic acid wapangidwa chifukwa cha kafukufuku waposachedwa. Kugwiritsa ntchito mankhwala awiri pamodzi kunakulitsa kuchuluka kwa antibacterial kanthu, kunathandizira kuthana ndi kukana kwa tizilombo toyambitsa matenda ambiri. Atapezeka kuti kuphatikiza kwabwino kwambiri kwa zinthu zogwira ntchito komanso chitetezo cha mankhwala, mankhwala osakanikirana adapangidwa ndi mankhwala othandizira-clavulanate a 7: 1, motero.

Dzinalo

Amoxiclav 2x (kuchokera ku Latin - Amoxiklav 2x).

Zosagwirizana Padziko Lonse

World Health Organisation yapatsa mankhwalawo dzina ladziko lonse losavomerezeka - amoxicillin + clavulanic acid.

Kodi 2x amatanthauza chiyani mdzina la mankhwalawa

Mankhwala ndi kuphatikiza kwa zinthu ziwiri zomwe zimagwirizana ndi zomwe wina akuchita. Zomwe zimapangidwira komanso kuchuluka kwa antioxotic (500 mg ndi 875 mg) ndizomwe zimayambitsa chiwonetsero mu dzinalo.

Fomu la mapiritsi linapangidwa kuti lithe kupulumutsira zovuta kwambiri komanso kupewa matenda opatsirana, malinga ndi kafukufuku waposachedwa pa luso la mankhwala othandizira.

Kutulutsa mafomu ndi kapangidwe kake

Mapiritsi a Amoxiclav ndi awa:

• amoxicillin - mankhwala a penicillin okhala ndi zochita zambiri za antibacterial,
• clavulanic acid - woletsa wa β - lactamase, kupewa kuwonongedwa kwa amoxicillin,
• zina zowonjezera pakatikati ndi zipolopolo za mapiritsi: colloidal silicon dioxide, magnesium stearate, cellulose, crospovidone, croscarmellose sodium, triethyl citrate, hydroxypropyl cellulose, polysorbate, titanium dioxide E171, talc.

Amoxicillin ndi clavulanate amaphatikizidwa ndi chiŵerengero cha 7: 1. Mankhwala amapezeka mu mawonekedwe a mapiritsi awiri Mlingo:

• 625 mg (500 mg + 125 mg),
• 1000 mg (875 mg + 125 mg).

Clavulanic acid ili mgulu lofanana (125 mg), wochepa mokwanira kuwonetsa ntchito zake zonse.

Mapiritsi ali ndi matuza a zojambulazo ndipo amaikidwa mu zidutswa 14 mumapaketi a makatoni okhala ndi malangizo ogwiritsira ntchito.

Limagwirira zake ntchito amoxiclav 2x

Mankhwala

Amoxiclav ali ndi mawonekedwe owonjezereka ochitapo kanthu. Mankhwalawa amagwira ntchito yolimbana ndi tizilombo toyambitsa matenda tokhala ndi amoxicillin, komanso ma bacteria omwe amalimbana ndi penicillin chifukwa chopanga ma beta-lactamases: gram-negative and gram-aerobes, anaerobes, spirochetes.

Clavulanic acid imamanga mabakiteriya oteteza mabakiteriya, amapanga minyewa yolimba, yomwe imakhala yogwira mwachilengedwe ndipo imatuluka mwachangu mthupi. Izi zimathandizira kuti maantibayotiki awonetse antimicrobial katundu wake ndikuwononga mabakiteriya oyipa, ndikuwononga khoma lawo.

Kuchuluka kwa amoxicillin kumakupatsani mwayi wothana ndi pneumococci ambiri, omwe ma penicillin ena alibe mphamvu.

Kuwonjezeka kwa mlingo wa tsiku ndi tsiku kwinaku akumachepetsa nthawi yamankhwala ndikofala masiku ano.

Kuchepetsa kuchuluka kwa clavulanate (poyerekeza ndi mankhwala osakanikirana kale) kumathandizira kulolerana kwa mankhwalawo ndikusungabe zochitika zokwanira kuti musayambitsa β-lactamases.

Pharmacokinetics

Magawo a zinthu ziwiri zomwezi amagwiranso ntchito muzochita zamankhwala ndi bioavailability. Onsewa amatengeka kwambiri m'mimba. The bioavailability wa clavulanate ndi oposa 60%, mu amoxicillin amafika 95%. Pazinthu zochizira, zinthu zimapezeka m'matumbo amisempha, mbali zonse za bronchopulmonary system (kuphatikizapo bronchial secretion ndi madzi a pleural), ziwalo za ENT (khutu lapakati, matoni), zotumphukira ndi zotumphukira, ma genitourinary system, ndi ziwalo za pelvic.

Zinthu zodutsa chotchinga, mu mkaka wa m'mawere mumapezeka zochuluka. Amalowetsa chingwe cha msana posakhazikika bwino ndipo sagwira ntchito ndi meningitis. Amamangiriza mapuloteni amwazi pafupifupi 20% mpaka 30% ya chinthucho.

Chiyero chochepetsetsa kwambiri cha matenda chimagwira pafupifupi 40% ya nthawi yayitali pakati pa Mlingo, pokhapokha ngati imagwiritsidwa ntchito kawiri pa tsiku limodzi ndi nthawi yomweyo. Hafu ya moyo wa amoxicillin wokhala ndi clavulanic acid amakhala pafupifupi maola 1.5. Mankhwalawa amachotseredwa ndi impso osasinthika, clavulanate amapezeka mu chiwindi, ndipo ambiri amasiya thupi mthupi.

Kodi mapiritsi a amooticlav 2x amachokera kuti

Amoxiclav zotchulidwa matenda a bakiteriya:

• matenda amtunduwu
• sinusitis (nthawi yayitali komanso yovuta),
• kuwonongeka pakhungu ndi minofu yofewa, kuphatikiza zilonda za septic, kuluma, purifiyamu ndi sepsis,
• zotupa mu mkamwa ndi maxillofacial dera,
• matenda a minofu, mafupa a mafupa ndi mafupa,
• chanchlon, chinzonono,
• mitundu yosiyanasiyana ya matenda oyambitsidwa ndi anaerobic ndi ma tizilombo toyambitsa matenda aerobic.

Mankhwala ndi othandiza mankhwalawa bile ducts, ENT ziwalo, abscesses osiyanasiyana kutulutsa. Njira ya mankhwalawa imagwiritsidwa ntchito popewa matenda opatsirana pambuyo pake.

Contraindication

Milandu yotsutsana kwathunthu ndi mankhwalawa ndi:

• Hypersensitivity chilichonse mankhwala zikuchokera mankhwala, kuphatikizapo othandizira,
• thupi lawo siligwirizana ndi cephalosporins, monobactams kapena mankhwala ena a beta-lactam m'mbiri
• kulephera kwamtundu uliwonse komwe kwachitika chifukwa cha mankhwala opha maantibayotiki,
• matenda mononucleosis,
• lymphocytic leukemia.

Osakupatsani mankhwala mwanjira iyi kwa odwala omwe ali ndi zaka zosakwana 12 ndi masekeli osakwana 40.

Momwe mungatenge Amoxiclav 2x

Pokhala ndi kuchuluka kowonjezera, mapiritsiwo ndi okulirapo. Sizovomerezeka kugawa magawo, kutafuna kapena kuphwanya umphumphu wa chipolopolo. Mapiritsiwo amameza lonse ndi madzi ambiri (osachepera 200 ml).

Ndi njira ya chithandizo, kuchuluka kwa madzimadzi oledzera sikuyenera kukhala ochepera 2 malita patsiku. Popewa dysbiosis, ma probiotic amapatsidwa limodzi.

Kuchepetsa zovuta zoyipa kuchokera m'matumbo am'mimba komanso kupewa kutulutsa kwa pseudomembranous colitis, mankhwalawa amatengedwa kumayambiriro kwa chakudya.

Mlingo wa tsiku ndi tsiku komanso chithandizo cha mankhwalawa zimayikidwa payekhapayekha ndipo zimatengera kuopsa kwa matendawa komanso momwe thupi limayankhira pomvera. Wokhazikika, 1 g ya mankhwalawa imapangidwa (fomu 875/125) maola 12 aliwonse. Kutalika kwa chithandizo kumatha kusintha kuchokera masiku 5 mpaka milungu iwiri.

Pofuna kupewa zovuta pa ntchito

Fomu ya Mlingo imagwiritsidwa ntchito kwambiri pakuchita opareshoni: mu mano ndi zodzikongoletsera, komanso pakugwira ntchito pamimba. Pofuna kupewa matenda opatsirana pambuyo polowera ziwalo zam'mimba, mafupa am'mimba, ndulu ya mtima, ndi mtima dongosolo, masiku 5 a mankhwalawa amagwiritsidwa ntchito. Mlingo wa tsiku ndi tsiku umatsimikiziridwa ndi dokotala potengera zomwe akuwonetsa.

Amoxiclav imaphatikizidwa pamndandanda wamankhwala a odwala omwe akuwonjezera impso, corteryary artery bypass grafting, kuphatikizidwa kwa valavu yamtima.

Matenda a kwamkodzo thirakiti

Kuthekera kwa mankhwalawa kupanga mapangidwe azinthu zambiri mu genitourinary system imagwiritsidwa ntchito pochiza matenda a pyelonephritis, cystitis, ndi urethritis wa bakiteriya. Kutalika kwa mankhwala kumatsimikiziridwa ndi adokotala, kutengera mtundu womwe wapezeka, atha kuyambira masiku 5 mpaka 14.

Mitundu yosakanikirana yamatenda imayendera bwino pochiza ndi mankhwala ophatikiza, osafuna chithandizo chamankhwala osiyanasiyana. Mankhwalawa ali ndi nephrotoxicity yocheperako ndipo amafulumira kuthira mkodzo, amakupatsani mwayi kuti muchotse mabakiteriya okhala ndi matenda a genitourinary system.

Zotsatira zoyipa

Mlingo watsopano, amoxicillin wokhala ndi clavulanate amalekeredwa bwino kuposa omwe adalipo kale, zotsatira zoyipa sizachilendo. Nthawi zambiri, pamakhala zosayenera mankhwala kuchokera m'mimba thirakiti: m'mimba, nseru, kusanza. Zizindikiro zimayambira pang'onopang'ono ndipo zimatha pambuyo pakutha kwa chithandizo.

Mwa mawonekedwe a matupi awo sagwirizana - urticaria, edema. Zizindikiro zowopsa - kupweteka, kusokonezeka, mantha a anaphylactic, kuchepa kwa minofu - kumawonetsa kusalolera kwa mankhwala, kuwonongeka kwa impso, kapena kugona mopitirira muyeso.

Bongo

Zizindikiro zoyambirira: matumbo ndi matumbo, kusowa kwam'mimba, mutu, tachycardia. Kugwiritsa ntchito mankhwala osokoneza bongo kwa nthawi yayitali kumatha kubweretsa kukhumudwa, kuchepa kwa magazi, komanso kulephera kwa impso.

Palibe mankhwala apadera; chithandizo ndi chisonyezo. Thandizo loyamba - kubwezeretsa koyenera kwa madzi-electrolyte (kumwa kwambiri), kutumphuka kwa m'mimba ndi kudya ma sorbents. Hemodialysis amachotsa bwino magawo onse a mankhwalawa.

Zolemba zogwiritsira ntchito

Pa mimba ndi mkaka wa m`mawere

M'maphunziro a nyama, palibe zoyipa zochokera kugwiritsidwa ntchito kwa mankhwalawa panthawi yomwe muli ndi pakati, zotsatira za kubala kwa mwana kapena kubereka kwakatulutsidwa.

Chifukwa cha kuchuluka kwa mankhwalawa ophatikiza mankhwala ophatikizira pakati pa nthawi yomwe ali ndi pakati, mankhwalawa amatha kuthandizidwa molingana ndi zofunikira pokhapokha pakufunika, ndipo pokhapokha ngati phindu la chithandizo likupita patsogolo kwa thanzi la mayi ndi mwana wosabadwayo.

Zinthu zonse ziwirizi zimapita mkaka wa m'mawere. Kukhazikika kwa mankhwala pa nthawi yoyamwitsa kungayambitse matenda am'mimba komanso fungal matenda a mucous nembanemba a mwana. Mwina chitukuko cha thupi lawo siligwirizana. Pakakhala mawonekedwe a zisonyezo, kuyamwitsa kuyimitsidwa kwakanthawi.

Mankhwala amaloledwa kugwiritsidwa ntchito pa mkaka wa kuyang'aniridwa ndi achipatala, atawunika kuchuluka kwa mapindu ake ndi chiopsezo.

Muubwana

Fomu ya mankhwalawa (mapiritsi) imadziwika ndi kuchuluka, mulingo waukulu ndipo samapangidwira odwala osakwana zaka 12 kapena ana olemera mpaka 40 kg. Zikatero, mankhwala amtundu wa antibayotiki amatchulidwa mwa kuyimitsidwa pakamwa kapena madzi.

Ndi mkhutu aimpso ntchito

Amoxiclav mwanjira imeneyi sagwiritsidwa ntchito pochiza matenda ngati, malinga ndi zotsatira za kafukufuku, mtundu wa clearinine chilolezo chotsika 30 ml / min. Pakakhala vuto losakwanira la impso, kusintha kwa mankhwalawa komanso kuwonjezeka kwakatikati pakati Mlingo zofunika. Chifukwa chake, mankhwalawa nthawi zambiri amasinthidwa ndi analogi ndi mlingo wotsika.

Ngati ndi kotheka, amoxiclav / clavulanate 1000 mg (875/125 mg) akhoza kutumizidwa chifukwa cha kupweteka kwambiri kwa aimpso mu piritsi limodzi patsiku. Ndi anuria, nthawi yapakati pakati Mlingo wa mankhwalawa imakulitsidwa mpaka masiku awiri kapena kuposerapo.

Ndi chiwindi ntchito

Zotsatira zoyipa za chiwindi zimapezeka ndi maphunziro a nthawi yayitali. Nthawi zambiri, zamatsenga zimadziwika mwa amuna okulirapo kuposa zaka zapakati. Mwa akazi, zotupa ndizosowa.

Ndi kulephera kwa chiwindi, chithandizo chimayikidwa mosamala, kuwunika ntchito ya chiwindi nthawi zonse.

AMOKSIKLAV

• Zizindikiro zogwiritsidwa ntchito
• Njira yogwiritsira ntchito
• Zotsatira zoyipa
• Contraindication
• Mimba
• Kuchita ndi mankhwala ena
• Bongo
• Kutulutsa Fomu
• Malo osungira
• Kupanga
• Zosankha

Amoxiclav - antibacterial kuphatikiza mankhwala.Zosakaniza zogwira ntchito: amoxicillin - mankhwala a penicillin gulu lochita zinthu zingapo komanso beta-lactamase inhibitor wa tizilombo - clavulanic acid. Clavulanic acid imalepheretsa kuwonongeka kwa amoxicillin chifukwa cha mapangidwe okhazikika a malo okhala ndi beta-lactamases: mwanjira iyi, maofesi omwe amapangidwa ndi osagwira komanso osasunthika.

Amoxicillin imagwira ntchito motsutsana ndi mabakiteriya omwe amamva nayo. Chifukwa chophatikizidwa ndi beta-lactamase inhibitor (clavulanic acid) mu mankhwalawa, mankhwalawa amatha kuperekedwanso matenda opatsirana ndi amoxicillin. Amoxicillin osakanikirana ndi clavulanic acid amagwira ntchito motsutsana: Streptococcus pneumonia, Str. bovis, Str. pyogene, Listeria spp., Staphylococcus aureus, S. epidermidis, Enterococcus spp. . ., Peptococcus spp., Clostridium spp., Actinomyces israelii, Peptostreptococcus spp.).

Mwambiri, magawo a pharmacokinetic a clavulanic acid ndi amoxicillin ndi ofanana akamagwiritsidwa ntchito palimodzi, chifukwa chake, alibe mphamvu pamagulu a zinthu zamtundu wa pharmacokinetic. Pambuyo pa kayendetsedwe ka mkati, zonse ziwiri zimaphatikizidwa bwino. Kuzama kwa plasma kwakukulu kumafikiridwa patatha pafupifupi mphindi 60. Kugwiritsa Amoxiclava Ndi chakudya sizikhudza mayamwidwe a clavulanic acid ndi amoxicillin. Hafu ya moyo wa clavulanic acid ndi mphindi 60-70, kwa amoxicillin - mphindi 78. Zonsezi zimalowa mkati mwa minyewa ndi manyuzipepala amadzimadzi mosavuta, makamaka kudziunjikira zobisika zamkati zam'mapapo, mapapo, mkati mwa khutu, mkati mwazinthu zam'mimba komanso zotulutsa za m'mimba, mazira ndi chiberekero. Pamene meningitis Amoxiclava kudutsa chotchinga magazi-chotchinga. Zimalowa mkatikati mwa chotchinga ndipo zimatsimikiziridwa mu kuchuluka kwa mkaka wamawere.

Ndi bolus makonzedwe Amoxiclava pa mlingo wa 1,2 g, kuchuluka kwakukulu kwa plasma ya clavulanic acid kumawonedwa pa 28,5 mg / l, amoxicillin - 105.4 mg / ml. Pambuyo mphindi 60, kuchuluka kwakukulu kwa zinthu izi mumadzi amthupi kumatsimikizika. Clavulanic acid ndi amoxicillin onse amapanga mapuloteni a plasma, motero, mwa 22-30% ndi 1720%.

Clavulanic acid imakhala ndi kagayidwe kakakulu mu minyewa ya chiwindi. Imapukusidwa pang'ono ndi mpweya komanso ndowe zomwe zatha, makamaka impso. Amoxicillin amapukusidwa osasinthika mkodzo.

Zizindikiro zogwiritsidwa ntchito

Njira yogwiritsira ntchito

Mapiritsi a Amoxiclav
Musanagwiritse ntchito, mapiritsi amasungunuka mu theka kapu yamadzi (osachepera 100 ml). Pambuyo pake, kuyimitsidwa komwe kumayambitsidwa kumasakanizidwa bwino kapena mapiritsi osafunidwa musanameze. Amayikidwa mkati mwa ana okhala ndi thupi lolemera makilogalamu 40 kapena kupitirira apo, komanso akulu. Mlingo wamba wa tsiku ndi tsiku ndi 375 mg (piritsi 1) maola 8 aliwonse (3 r / tsiku), kapena 625 mg (piritsi 1) 2-3 r / tsiku (kutengera ndi zovuta za matendawa).

Mapiritsi a Amoxiclav 2X
Amangolembera odwala okhawo omwe ali ndi matenda opumira kwambiri kapena matenda oopsa, 1000 mg (piritsi limodzi) kawiri pa tsiku.

Amoxiclav mu ana
Ana kuyambira masiku oyamba amoyo mpaka miyezi itatu amapatsidwa mankhwala a 30 mg / kg / tsiku (malinga ndi amoxicillin), tsiku lililonse mlingo umagawidwa mosiyanasiyana, amatengedwa pafupipafupi.
Amoxiclav amalembedwa kuyambira azaka zitatu kapena kuposerapo kapena kulemera kwa thupi zosakwana 40 makilogalamu pa 25 mg / kg / tsiku (logawidwa m'magawo awiri maola 12 aliwonse), kapena 20 mg / kg / tsiku (logawidwa magawo atatu aliwonse maola) - matenda opatsirana azovuta.

Mu matenda opweteka kwambiri, Amoxiclav amagwiritsidwa ntchito pa 45 mg / kg / tsiku (mlingo womwe umagawidwa ma 2 Mlingo uliwonse 12), kapena 40 mg / kg / tsiku (logawidwa mu 3 waukulu maola 8 aliwonse).

Mlingo wapamwamba wa tsiku lililonse wa ana ndi 45 mg pa kilogalamu imodzi ya kulemera kwa thupi. Pazipita tsiku lililonse la clavulanic acid monga mchere wa potaziyamu ndi 10 mg pa kilogalamu imodzi ya thupi.
Pankhani ya matenda opatsirana pang'ono, mlingo wa tsiku ndi tsiku ndi 25 mg / kg maola 12 aliwonse (kutengera amoxicillin).
Kwa matenda am'munsi kupuma thirakiti, sinusitis, otitis media ndi matenda ena akulu, Amoxiclav amalembedwa kwa ana pamtunda wa 45 mg / kg / tsiku la amoxicillin maola 12 aliwonse.

Odwala omwe ali ndi vuto la impso
Ngati osakwanira aimpso ntchito ndi creatinine chilolezo cha 10 ml / mphindi kapena zochepa, Mlingo wa Amoxiclav kusintha kapena nthawi pakati Mlingo wa mankhwala kuchuluka. Mu anuria, gawo pakati Mlingo akhoza kukhala 48 maola.
Ndi creatinine chilolezo cha 80 ml / mphindi kapena kupitilira, gawo pakati kutenga Amoxiclav ndi maola 8, chilolezo cha 80-50 ml / mphindi - maola 8, chilolezo cha 50-10 ml / mphindi - maola 12, chilolezo cha 10 ml / mphindi ndi ochepera 0 Maola 24

Amoxiclav - kuyimitsidwa
Mlingo weniweni wa kuyimitsidwa kwa Amoxiclav kwa odwala a ana amawerengeredwa pokhapokha poganizira kulemera kwa thupi.
Asanakonzekere kuyimitsidwa kwa mankhwalawo, vial imagwedezeka bwino mpaka zigawo za ufa zimasiyanitsidwa pansi ndi makhoma a chotengera. 86 ml ya madzi amawonjezeredwa m'botolo mumalilonse awiri, madzi onse akawonjezeredwa botolo limagwedezeka. 1 scoop wotenga Amoxiclav kuyimitsidwa muli 5 ml ya mankhwala, theka - 2,5 ml, ¾ - 3,75 ml.

Kuzizira kozizira Amoxiclav sikuloledwa.

Perekani kwa ana azaka zopitilira 12 (kapena masekeli 40 kapena kupitilira) ndi akulu (kudzera m'mitsempha) 1.2 g maola 8 aliwonse. Mu ana - kwa ana kuyambira miyezi itatu mpaka 12 - 30 mg / kg maola 8 aliwonse. Woopsa, mankhwalawa amatumizidwa maola 6 aliwonse (kwa ana ochepera miyezi 3 - 30 mg / kg maola 8 aliwonse). Ana a masiku oyamba a moyo, kuphatikiza ana akhanda, amasankhidwa Amoxiclav 30 mg / kg maola 12 aliwonse. Mukakwaniritsa achire zotsatira ndi bolus makonzedwe a Amoxiclav, mutha kusintha pakamwa makonzedwe. Mankhwala a Amoxiclav kwa ana ndi akulu amapitilira masiku 14.

Ntchito yoletsa purcin-septic zovuta musanachite opareshoni
Perekani pamaso pa makonzedwe a anesthesia ndi 1.2 g kudzera mkatikati: pakuchitika kwakanthawi - kamodzi, komanso nthawi yayitali (kupitirira mphindi 60) makonzedwe owonjezera akufunika - 1,2 g (pazambiri - mpaka kanayi pa tsiku). Ali pachiwopsezo chachikulu chotenga matenda opatsirana, Amoxiclav imapitilizidwa kutumikiridwa kudzera m'mitsempha kapena pakamwa panthawi yothandizira, makamaka ngati panthawi ya opareshoni panali zizindikiro zowoneka bwino zothandizira matenda opatsirana (panthawiyi, kulowetsedwa kwa intravenous pambuyo pa opareshoni kupitilira).

Ndi kulephera kwa aimpso
Ngati aimpso kulephera, mlingo wa mtsempha wa magazi makonzedwe amawerengedwa malinga ndi chilolezo cha creatinine: pachilolezo cha 30 ml / mphindi kapena kupitirira apo, mulingo woyenera umasinthidwa, pakudziwika kwa 10-30 ml / min, mankhwalawa amayamba ndi makonzedwe a mtsempha wa 1.2 g, ndiye kuti g mg maola 12 aliwonse, chilolezo cha 10 ml / mphindi kapena kuchepera apo, mankhwalawa amayamba ndi mtsempha wa mtsempha wa 1.2 g, ndiye kuti 600 mg amatumikiridwa kudzera mkati ndi maola a 24. Pakakhala kulephera kwa impso kwa ana, kusintha kwamankhwala kumachitikanso. Wodwala akakhala ndi hemodialysis, ndiye kuti 85% ya mankhwalawa amachotsedwa m'thupi. Pambuyo pa hemodialysis, Amoxiclav amapatsidwa mlingo wa 600 mg mu mtsempha wa magazi. Mankhwala sapatula peritoneal dialysis, kotero kusintha kwa mankhwala sikofunikira.

Amoxiclav Quicktab
Musanagwiritse ntchito, mapiritsi amasungunuka mu theka kapu yamadzi (osachepera 100 ml). Pambuyo pake, kuyimitsidwa komwe kumayesedwako kumasakanizidwa bwino kapena kutafuna musanameze. Amoxiclav Quicktab imatengedwa bwino kumayambiriro kwa chakudya.

Kwa ana omwe ali ndi thupi lolemera makilogalamu 40 kapena kupitilira apo, komanso kwa akulu, tsiku lililonse Amoxiclav Quiktab ndi 500 mg ya amoxicillin ndi 125 mg ya clavulanic acid (piritsi 1) 2-3 r / tsiku lililonse maola 8-12, kapena 875 mg / 125 mg (1 piritsi) 2 r / tsiku lililonse maola 12.

Ndi kulephera kwa aimpso
Kutha kwa clavulanic acid ndi amoxicillin mu kulephera kwa impso kumachedwetsedwa, motero, mlingo wa mankhwalawa umachepetsedwa malingana ndi kuopsa kwa magwiridwe antchito. Mutha kuonjezera nthawi pakati pa kumwa mankhwalawa. Pankhani ya kufooka kwa aimpso ndi kuvomerezeka kwa creatinine kwa 0,166-0,5 ml / s, Amoxiclav Quiktab amalembedwa pa 500 mg / 125 mg (piritsi 1) 2 r / tsiku lililonse maola 12. Ndi chilolezo chochepera 0,166 ml / s, mlingo wa 500 mg / 125 mg (piritsi 1) umagwiritsidwa ntchito 1 r / tsiku (maola 24 aliwonse).

Zotsatira zoyipa

Contraindication

Mimba

Kuchita ndi mankhwala ena

Bongo

Kutulutsa Fomu

Mapiritsi a Amoxiclav - 250 mg ya amoxicillin / 125 mg wa clavulanic acid, wolemba-filimu, phukusi - 15 zidutswa.

Mapiritsi a Amoxiclav 2X - 500 mg / 125 mg, 875 mg / 125 mg, filimu yokutira, (phukusi - zidutswa 10 kapena 14).

Amoxiclav pakamwa kuyimitsidwa - 312,5 mg / 5 ml (250 mg ya amoxicillin pa 5 ml ya kuyimitsidwa / 62,5 mg wa clavulanic acid pa 5 ml ya kuyimitsidwa), 156.25 mg / 5 ml (125 mg wa amoxicillin 5 ml ya kuyimitsidwa / 31.25 mg wa clavulanic acid pa 5 ml ya kuyimitsidwa) - botolo lokonzekera 100 ml ya kuyimitsidwa, phukusi - 1 botolo.

Amoxiclav kwa makina a makolo - ufa wokonzekera njira yothetsera utsi m'mitsempha ya 600 mg mu botolo (500 mg ya amoxicillin ndi 100 mg wa clavulanic acid) kapena 1.2 g mu botolo (1000 mg ya amoxicillin ndi 200 mg wa clavulanic acid) .

Malo osungira

Mapiritsi a Amoxiclav 250 mg / 125 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 250 mg, clavulanic acid) mu mawonekedwe a potaziyamu mchere 500 mg.
Zinthu zosagwira: microcrystalline cellulose, sodium croscarmellose.

Amoxiclav 156.25 mg / 5 ml kuyimitsidwa ufa
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 125 mg / 5 ml, clavulanic acid) mu mawonekedwe a mchere wa potaziyamu 31.25 mg / 5 ml.
Zinthu zopanda ntchito: sodium citrate, cellcrystalline cellulose, sodium benzoate, sodium saccharin, mannitol.

Ufa wa kuyimitsidwa Amoxiclav 312,5 mg / 5 ml
Zinthu zomwe zimagwira ntchito: amoxicillin (mwa mawonekedwe a trihydrate) 250 mg / 5 ml, clavulanic acid) monga potaziyamu 62,5 mg / 5 ml.
Zinthu zopanda ntchito: sodium citrate, cellcrystalline cellulose, sodium benzoate, sodium saccharin, mannitol.

Ufa wa kulowetsedwa kulowetsedwa Amoxiclav 600 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a mchere wa sodium) 500 mg, clavulanic acid) monga potaziyamu 100 mg.

Ufa wa kulowetsedwa kulowetsedwa Amoxiclav 1200 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a mchere wa sodium) 1000 mg, clavulanic acid) monga potaziyamu 200 mg.

Mapiritsi a Amoxiclav 2X 500 mg / 125 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 500 mg, clavulanic acid) mu mawonekedwe a potaziyamu mchere 125 mg.
Zinthu zopanda ntchito: anhydrous colloidal silicon dioxide, aspartame, kununkhira kwa lalanje, kusakaniza kwa malo otentha, yellow iron oxide (E172), hydrogenated castor mafuta, talc, microcrystalline cellulose silrate.

Mapiritsi a Amoxiclav 2X 875 mg / 125 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 875 mg, clavulanic acid) monga potaziyamu mchere wa 125 mg.
Zinthu zopanda ntchito: anhydrous colloidal silicon dioxide, aspartame, kununkhira kwa lalanje, kusakaniza kwa malo otentha, yellow iron oxide (E172), hydrogenated castor mafuta, talc, microcrystalline cellulose silrate.

Amoxiclav Quicktab mapiritsi 500 mg / 125 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 500 mg, clavulanic acid) mu mawonekedwe a potaziyamu mchere 125 mg.
Zinthu zopanda ntchito: anhydrous colloidal silicon dioxide, aspartame, kununkhira kwa lalanje, kusakaniza kwa malo otentha, yellow iron oxide (E172), hydrogenated castor mafuta, talc, microcrystalline cellulose silrate.

Mapiritsi a Amoxiclav Quicktab 875 mg / 125 mg
Zinthu zomwe zimagwira ntchito: amoxicillin (mu mawonekedwe a trihydrate) 875 mg, clavulanic acid) monga potaziyamu mchere wa 125 mg.
Zinthu zopanda ntchito: anhydrous colloidal silicon dioxide, aspartame, kununkhira kwa lalanje, kusakaniza kwa malo otentha, yellow iron oxide (E172), hydrogenated castor mafuta, talc, microcrystalline cellulose silrate.

Zosankha

Ndi chisamaliro Amoxiclav zotchulidwa kwa odwala omwe amawonetsa mayankho am'mbuyomu. Pali kuthekera kwa kuyanjana pakati pa ma penicillin ndi mankhwala a cephalosporin, motero, mosamala Amoxiclav omwe ali ndi matupi awo sagwirizana ndi cephalosporins.
Pa vuto la chiwindi, kuwunika kwa mayesero a chiwindi ndikofunikira.

Mu 95% ya odwala khansa ya m'mimba ndi matenda a mononucleosis Amoxiclava limodzi ndi chitukuko cha zotupa pakhungu, odwala oterewa saloledwa kugwiritsa ntchito mankhwalawa.
Odwala omwe ali ndi vuto lowonongeka la impso, mlingo umasankhidwa payekha, kuwonjezeka kwakanthawi pakati pamajekeseni a mankhwala amaloledwa.

Mukamachitira mankhwala, tikulimbikitsidwa kugwiritsa ntchito madzi ambiri kapena madzi ena.
Amoxiclav imadzetsa zabodza pazotsatira za Coombs ndi kuyesedwa kwa Benedict (kudziwa kuchuluka kwa shuga mumkodzo). Chifukwa chake, tikulimbikitsidwa kugwiritsa ntchito mayeso a shuga, omwe amachokera pa enzymatic oxidation reaction.

Mapiritsi a Amoxiclav - malangizo a boma ogwiritsira ntchito

MALANGIZO
pa kugwiritsa ntchito mankhwalawa
ntchito zamankhwala

Werengani malangizo awa mosamala musanayambe kumwa / kugwiritsa ntchito mankhwalawa.
Sungani bukuli, lingafunenso.
• Ngati muli ndi mafunso, funsani dokotala.
• Mankhwalawa amaperekedwa kwa inu panokha ndipo sayenera kugawana ndi ena, popeza amathanso kuwavulaza ngakhale mutakhala ndi zofanana ndi inu.

Nambala yolembetsa

Mlingo

Mapiritsi okhala ndi mafilimu

Zinthu zothandizira (pakati): piritsi lililonse la 250mg + 125mg lili ndi 250 mg ya amoxicillin mu mawonekedwe a trihydrate ndi 125 mg ya clavulanic acid mu mawonekedwe a mchere wa potaziyamu,
piritsi lililonse la 500mg + 125mg lili ndi 500 mg ya amoxicillin mu mawonekedwe a trihydrate ndi 125 mg ya clavulanic acid mu mawonekedwe a mchere wa potaziyamu,
piritsi lililonse la 875 mg + 125 mg limakhala ndi 875 mg ya amoxicillin mu mawonekedwe a trihydrate ndi 125 mg ya clavulanic acid momwe amapangira mchere wa potaziyamu.
Omwe amalandira chithandizo (chimodzimodzi pa kipimo chilichonse): silicon dioxide colloidal 5.40 mg / 9.00 mg / 12.00 mg, crospovidone 27.40 mg / 45.00 mg / 61.00 mg, croscarmellose sodium 27.40 mg / 35.00 mg / 47,00, magnesium stearate 12,00 mg / 20,00 mg / 17.22 mg, talc 13.40 mg (kwa 250 mg + 125 mg), cellcose ya microcrystalline mpaka 650 mg / mpaka 1060 mg / mpaka 1435 mg,
makanema othandizira mafilimu 250mg + 125mg - hypromellose 14.378 mg, ethyl cellulose 0,702 mg, polysorbate 80 - 0,780 mg, triethyl citrate 0,793 mg, titanium dioxide 7.605 mg, talc 1.742 mg,
makanema othandizira mafilimu 500mg + 125mg - hypromellose 17.696 mg, ethyl cellulose 0,864 mg, polysorbate 80 - 0.960 mg, triethyl citrate 0,976 mg, titanium dioxide 9.360 mg, talc 2.144 mg,
makanema othandizira mafilimu 875mg + 125mg - hypromellose 23.226 mg, ethyl cellulose 1.134 mg, polysorbate 80 - 1,260 mg, triethyl citrate 1.280 mg, titanium dioxide 12.286 mg, talc 2.814 mg.

Kufotokozera

Mapiritsi a 250 mg + 125 mg: oyera kapena pafupifupi oyera, oblong, octagonal, biconvex, mapiritsi okhala ndi mafilimu okhala ndi ma Prints 250/25 mbali imodzi ndi AMC mbali inayo.
Mapiritsi 500 mg + 125 mg: oyera kapena pafupifupi oyera, oval, mapiritsi a biconvex, filimu yokutira.
Mapiritsi a 875 mg + 125 mg: oyera kapena pafupifupi oyera, oblong, biconvex, mapiritsi okhala ndi mafilimu okhala ndi notch komanso chithunzi cha "875/125" mbali imodzi ndi "AMC" mbali inayo.
Onani pa kink: misa yachikasu.

Zizindikiro zogwiritsidwa ntchito

Matenda oyambitsidwa ndi tizilombo tating'onoting'ono tating'ono:
• Matenda am'mapapo apakati a kupuma ndi ziwalo za ENT (kuphatikizapo pachimake ndi matenda osachiritsika, mafupa am'mimba komanso otitis, pharyngeal abscess, tonsillitis, pharyngitis),
• matenda ochepa kupuma thirakiti (kuphatikizapobronchitis pachimake ndi bakiteriya wamphamvu, matenda a chifuwa, chibayo),
• matenda amkodzo thirakiti,
• matenda ku matenda azachipazi,
• matenda a pakhungu ndi minofu yofewa, komanso mabala ochokera pakuluma kwa anthu ndi nyama,
• matenda a mafupa komanso osakanikirana,
• matenda am'mimba thirakiti (cholecystitis, cholangitis),
• odontogenic matenda.

Gwiritsani ntchito pa nthawi yoyembekezera komanso nthawi yoyamwitsa

Kafukufuku wazinyama sanawululire zowopsa za kumwa mankhwalawa panthawi yomwe ali ndi pakati komanso momwe zimakhudzira kukula kwa fetal.
Kafukufuku m'modzi mwa azimayi omwe ali ndi vuto la zamkati mwachangu anapeza kuti kugwiritsa ntchito prophylactic wa amoxicillin / clavulanic acid kumatha kuphatikizidwa ndi chiopsezo chowonjezeka cha necrotizing enterocolitis mwa akhanda.
Pa nthawi yoyembekezera komanso mkaka wa m'mawere, mankhwalawa amagwiritsidwa ntchito pokhapokha ngati phindu lomwe limaperekedwa kwa mayi limaposa chiwopsezo cha mwana wosabadwayo ndi mwana.
Amoxicillin ndi clavulanic acid ochepa omwe amalowa mkaka wa m'mawere.
Mu makanda omwe amalandila yoyamwitsa, kukula kwa chidwi, kutsegula m'mimba, ma micidi a mucous nembanemba amkamwa amatha. Mukamamwa Amoxiclav ®, ndikofunikira kusankha pakuletsa kuyamwitsa.

Zotsatira zoyipa

Malinga ndi World Health Organisation (WHO), zotsatira zosafunikira zimagawidwa malinga ndi kuchuluka kwawo kwa chitukuko motere: pafupipafupi (≥1 / 10), nthawi zambiri (≥1 / 100, ® ndi probenecid, zimatha kuyambitsa komanso kulimbikira m'magazi a milingo ya amoxicillin, koma osati clavulanic acid, motero, kugwiritsa ntchito pamodzi kwa phenenecid sikulimbikitsidwa. Kugwiritsa ntchito pamodzi kwa Amoxiclav ® ndi methotrexate kumawonjezera kawopsedwe a methotrexate.
Kugwiritsa ntchito mankhwalawa molumikizana ndi allopurinol kungayambitse kukula kwa khungu lawo siligwirizana. Pakadali pano, palibe deta pakugwiritsa ntchito imodzi imodzi ya amoxicillin ndi clavulanic acid ndi allopurinol. Ntchito munthawi yomweyo disulfiram.
Amachepetsa mphamvu ya mankhwala pakukonza kagayidwe kamene para-aminobenzoic acid amapangidwira, ethinyl estradiol - chiopsezo cha magazi "kupunduka".
Mabukuwa amafotokoza za kawirikawiri kukwera kwa chiwopsezo cha odwala omwe amagwiritsidwa ntchito limodzi acenocumarole kapena warfarin ndi amoxicillin. Ngati kuli kofunikira kuti mugwiritse ntchito nthawi yomweyo ndi anticoagulants, ndikofunikira kuyang'anira nthawi yoyesedwa kapena INR popereka mankhwala kapena kusiya ntchito;
Ndi munthawi yomweyo kugwiritsa ntchito rifampicin kufooka kwa antibacterial zotsatira ndikotheka. Amoxiclav ® sayenera kugwiritsidwa ntchito nthawi imodzi kuphatikiza ndi ma bacteria a bacteriostatic (macrolides, tetracyclines), sulfonamides chifukwa kuchepa kotheka mu mphamvu ya Amoxiclav ®.
Amoxiclav ® imachepetsa kugwira ntchito kulera kwamlomo.
Odwala kulandira mycophenolate mofetil, atayamba kugwiritsa ntchito kuphatikiza amoxicillin ndi clavulanic acid, kuchepa kwa anthu omwe ali ndi metabolite, mycophenolic acid, adanenedwa, asanalandire mlingo wotsatira wa mankhwalawa pafupifupi 50%. Zosintha pamawonekedwe awa sizingawonetse moyenera kusintha kwamtundu wa mycophenolic acid.