Kodi ndingatenge Clarithromycin ndi Amoxicillin nthawi imodzi? Ndizoyenera kudziwa!

Amoxicillin ndi clarithromycin ndi ma antibacterial omwe amagwira ntchito motsutsana ndi matenda osiyanasiyana. Mankhwala amatha kugwiritsidwa ntchito palokha komanso nthawi imodzi. Mukamapereka mankhwala, ma virus ndi ma contraindication ayenera kukumbukiridwa.

Amoxicillin ndi clarithromycin ndi ma antibacterial omwe amagwira ntchito motsutsana ndi matenda osiyanasiyana.

Khalidwe la Amoxicillin

Maantibayotiki ophatikizana ndi pencillin amakhala ndi mphamvu yotsitsa, potengera kupangidwa kwa peptidoglycan, puloteni yomwe imagwiritsidwa ntchito popanga membrane wa cell ya microorganism. Mavuto otsatirawa ali ndi chidwi ndi mankhwalawa:

• gram-aerobes (streptococci, ena a staphylococcus),
• Gram-negative aerobes (meningococci, diphtheria bacillus, Klebsiella, gonococci, Salmonella, ena a Proteus tizilombo, Helicobacter pylori).

Ma tizilombo ena otsatirawa sagwirizana ndi Amoxicillin:

• zovuta zabwino za Proteus,
• magawo
• enterobacter
• Pseudomonas aeruginosa,
• majeremusi okhathamira (chlamydia, rickettsia, mycoplasma),
• tizilombo toyambitsa matenda a anaerobic.

Mankhwala amagwiritsidwa ntchito pochiza matenda otsatirawa:

• gastritis
• zilonda zam'mimba ndi duodenum,
• zotupa mu genitourinary dongosolo,
• matenda oyipa a pakhungu pakhungu ndi minofu yofewa,
• zotupa ndi zotupa za kupuma,
• gonorrhea wovuta
• meningitis
• mabakiteriya owononga thumba la mtima.

Amoxicillin amagwiritsidwa ntchito pochiza gastritis.

Kugwiritsa ntchito mankhwalawa kungapangitse zotsatirazi zotsatirazi:

• thupi lawo siligwirizana (urticaria, erythematous totupa, angioedema, febrile syndrome, minofu ndi ululu wolowa),
• kukulitsa kwa matenda omwe amalimbana ndi maantibayotiki,
• mitsempha yam'mitsempha yam'mimba (mutu, kukokana, chisokonezo),
• matenda am'mimba (kupweteka kwam'mimba, nseru ndi kusanza, kuchepa kwa chakudya, mapando otayirira).

Amoxicillin amatsutsana mu mononucleosis wopatsirana, matenda oopsa m'matumbo, leukemia. Mosamala, iyenera kugwiritsidwa ntchito ndi azimayi oyembekezera komanso oyembekezera.

Clarithromycin kanthu

Mankhwala ochepetsa mphamvu a macrolides angapo amalepheretsa mapangidwe a mapuloteni m'maselo a bakiteriya. Clarithromycin imalepheretsa kufalikira kwa tizilombo tating'onoting'ono popanda kuwawononga. Ma tizilombo tating'onoting'ono otsatirawa ali ndi chidwi ndi ntchito:

• gram-aerobes wabwino (streptococci, staphylococci, diphtheria bacillus, tuberculous mycobacteria),
• gram-negative aerobes (diphtheria bacillus, borrelia, enterobacter, pasteurella, meningococcus, helicobacter pylori, moraxella),
• majeremusi okhathamira (chlamydia, ureaplasma, toxoplasma, mycoplasma),
• anaerobes (clostridia, peptococcus, peptostreptococcus, fusobacteria).

Clarithromycin amalepheretsa kupangika kwa mapuloteni mu ma cell a bacteria.

Kuphatikiza

Kugwiritsa ntchito mankhwala osakanikirana kumathandizira kuchepetsa ntchito ya Helicobacter pylori, yomwe imayambitsa zilonda zam'mimba zam'mimba. Chithandizo choterechi chimachepetsa mwayi wa kukana kwa tizilombo toyambitsa matenda tizilombo toyambitsa matenda. Kukula kwa sipekitiramu ya kuchitapo kanthu kumapangitsa kuti matenda athetse mwachangu.

Contraindication

Kugwiritsa ntchito kwacacithromycin ndi amoxicillin kumatsutsana zotsatirazi:

• kusalolera kwa macrolides ndi penicillin,
• matenda akulu a impso ndi chiwindi,
• 1 trimester ya mimba
• khansa.

Mosamala, mankhwalawa amatengedwa ndi hemorrhagic diathesis, mphumu ya bronchial, mu 2nd ndi 3 trimester ya mimba.

Kufotokozera zamankhwala

Kwa zaka zambiri, chilonda cham'mimba chimathandizidwa ndi zakudya, kuchepa kwa secretion ya hydrochloric acid, ndipo m'malo ovuta kwambiri, opaleshoni yochotsa m'mimba. Chifukwa cha kupezeka kwa mgwirizano pakati pa matenda am'mimba am'mimba am'mimba komanso matenda a Helicobacter pylori, pomwe olemba adalandira Mphotho ya Nobel, zilonda zinayamba kuthandizidwa ndi maantibayotiki, kupulumutsa odwala pakufunika kochita opaleshoni yayikulu.

Kapangidwe ka clarithromycin ndi azithromycin kumaphatikiza zosakaniza zomwezo.

Njira yamachitidwe

Clarithromycin amasokoneza mapangidwe a mapuloteni m'maselo a bakiteriya, omwe amachititsa kuti ayambe kukula komanso kubereka.

Amoxicillin amasokoneza mapangidwe ofunikira a chipinda cha cell cha peptidoglycan, zomwe zimapangitsa kufa kwa tizilombo. Kusiyana kwamapangidwe a maantibayotiki kumakupatsani mwayi wophatikiza, ndikupeza zotsatira zabwino.

Clarithromycin ndi Amoxicillin amagwiritsidwa ntchito limodzi pochiza Helicobacter pylori, yomwe imayambitsa kukula kwa gastritis, zilonda zam'mimba ndi duodenum. Ndi gawo limodzi mwazomwe mungagwiritse ntchito mankhwalawa, koma amagwiritsidwa ntchito kuphatikiza ndi mankhwala ochokera ku magulu ena azachipatala.

Zizindikiro zogwiritsidwa ntchito munthawi yomweyo

Kuti mugwiritse ntchito munthawi yomweyo, mankhwala amasankhidwa mosamala. Maantibayotiki othandizira mabakiteriya a gastritis kapena chifuwa chachikulu sayenera kukhala ndi zotsatirapo zosiyanasiyana. Izi zimayenera kukhala ndi malo okhala acidic ndi alkaline.

Mankhwala ayenera kulowa m'magazi pamafunso, osayankhidwa ndi madzi a m'mimba.

Mankhwalawa amakhala ndi mgwirizano wa synergistic. Amoxicillin ndi Clarithromycin amawononga makoma a cell a mabakiteriya, zimayambitsa kulephera kwa tizilombo kuti kubereka komanso kufa kwa anthu.

Momwe mungatenge amoxicillin ndi clarithromycin palimodzi?

Ndi makonzedwe a munthawi yomweyo a mankhwalawa, aliyense wa iwo amalembedwa mogwirizana ndi malangizo. Ndi kuphatikiza mankhwala, Mlingo wambiri wa mankhwala onsewo ndi mankhwala. Mlingo watsiku ndi tsiku sayenera kupitirira 3 g, nthawi zambiri odwala amapatsidwa 750-1500 mg tsiku lililonse.

Mlingo wa tsiku ndi tsiku umagawidwa muyezo waukulu. Njira ya mankhwala kumatenga pafupifupi masiku 10.

Zizindikiro zamatenda zikadutsa, chithandizo chimapitirizidwanso kwa masiku ena awiri. Mankhwala onse awiriwa amapangidwira pakamwa. Dongosolo la chithandizo limasankhidwa ndi adokotala.

Malingaliro a madotolo pakugwirizana kwa Amoxicillin ndi Clarithromycin

Stepanov Victor Sergeevich, katswiri wa TB

Kuphatikiza kwa mankhwalawa ndi mankhwala othandizira chifuwa chachikulu. Mankhwala ndi othandizira pakatikati, koma kukana kwa tubercle bacillus ndizochulukirapo kuposa mankhwala ena.

Tkachenko Maria Nikolaevna, wothandizira

Zochizira bakiteriya sinusitis ndi sinusitis, mankhwalawa nthawi zambiri amapatsidwa mankhwala. Amathandiza kwambiri polimbana ndi matenda ngati amenewa. Mankhwalawa, muyezo wa mankhwala omwe dokotala watchulidwa uyenera kuchitika.

Khalidwe la Clarithromycin

Ma anti-synthetic antiotic ali m'gulu la macrolides. Mlingo wovomerezeka, umalepheretsa kubereka kwa tizilombo tating'onoting'ono tokhala m'matumbo, kwambiri - amawononga tizilombo toyambitsa matenda. Poyerekeza ndi ma antibacterial ena angapo a macrolides, Clarithromycin ali ndi mphamvu kwambiri motsutsana ndi Helicobacter pylori. Mankhwalawa amadziunjikira m'matumbo am'mimba, omwe amaloleza kuti azigwiritsidwa ntchito pakuwonetsa matenda amtunduwu.

Kodi ndingatenge nthawi yacacithromycin ndi amoxicillin nthawi imodzi?

Kugwiritsa ntchito antibacterial kuphatikiza kumathandiza kuthetsa tizilombo tating'onoting'ono monga:

• nsomba
• streptococcus
• staphylococcus
• E. coli
• chlamydia.

Clarithromycin ndi Amoxicillin amagwiritsidwa ntchito pa matenda otsatirawa:

• bakiteriya matenda am'mimba dongosolo (gastritis, zilonda zam'mimba, zotupa zoyipa chifukwa cha ntchito ya Helicobacter pylori),
• matenda opuma (bronchitis, chibayo, mitundu ya chifuwa chosagwirizana ndi chithandizo chamankhwala),
• yotupa matenda a genitourinary dongosolo (matenda a prostatitis, chlamydial urethritis, gonorrhea, kutupa kwa chiberekero ndi ziwindi, cystitis, pyelonephritis).

Clarithromycin amagwiritsidwa ntchito poteteza matenda am'mimba.

Pochiza matenda am'mimba, clarithromycin ndi amoxicillin amathandizidwa ndi omeprazole. Kuthekera kochira pamenepa ndi 95%. Pali mankhwala ovuta omwe ali ndi zosakaniza 3 zogwira ntchito.

The pharmacological zotsatira za maantiawiri awiriawiri

Helicobacter pylori imakula mofulumira kukana maantiotic. Kugwiritsa ntchito mankhwala a 2 kumathandizira kuchepetsa mwayi wokana. Amoxicillin osakanikirana ndi clarithromycin amachepetsa kufalikira kwa mabakiteriya. Mankhwala amalimbikitsa zochita za wina ndi mnzake. Izi zimatheka chifukwa cha zovuta zosiyanasiyana za tizilombo tosiyanasiyana.

Malingaliro a madotolo

Victoria, wazaka 48, katswiri wa TB, ku Moscow: "Clarithromycin ndi Amoxicillin nthawi zambiri amapatsidwa mitundu yovuta ya chifuwa chachikulu. Mankhwalawa ndi othandizira pakatikati, komabe, chifuwa chachikulu cha mycobacteria chimayamba kukana nawo. Zotsatira zoyipa zingapo ndi mankhwala ndizosowa. Mapiritsi amatha kubweretsa mutu, nseru, komanso kuwawa mkamwa. Zizindikiro zosasangalatsa zimatha mukamaliza kulandira chithandizo. "

Maria, wazaka 39, wazachipatala, Novosibirsk: “Kuphatikiza kwa maantibayotiki nthawi zambiri kumagwiritsidwa ntchito pochiza matenda a sinusitis ndi sinusitis. Mu gynecology, mankhwala amagwiritsidwa ntchito pochiza endometritis, adnexitis, chlamydia. Mankhwala ndi othandiza kwambiri polimbana ndi tizilombo toyambitsa matenda. Panthawi ya chithandizo, Mlingo wofotokozedwa ndi dokotala sayenera kupitilira. Kulephera kutsatira lamuloli kumawonjezera ngozi. ”

Amoxicillin sinafotokozeredwe tsankho la munthu pazamankhwala.

Ndemanga za Odwala

Natalia, wazaka 33, Izhevsk: “Pambuyo pa kuzizira, matenda a bronchitis osakhazikika adayamba. Matendawa adakula kawiri pachaka. Kutsokomola kwamphamvu kunasokoneza kugona ndi ntchito. Ndinatembenukira kwa dokotala wamapapu yemwe amandipatsa mankhwala, omwe amaphatikizapo kumwa Clarithromycin ndi Amoxicillin. Pambuyo mankhwala, matenda a bronchitis adayamba kuchuluka nthawi zambiri. Mukamamwa mankhwalawa, nseru nthawi zina zinkawonekera, zomwe zimatha atatha mankhwala. ”

Sergey, wazaka 58, Voronezh: “Ndikamayesedwa, chilonda cham'mimba chinapezeka. Kafukufuku akuwonetsa kuti matendawa amayamba chifukwa cha matenda a Helicobacter pylori. Clarithromycin adayikidwa limodzi ndi amoxicillin. Anamwa mankhwalawa kwa masiku 10, pambuyo pake anapatsanso mayeso. Wothandizirana naye sanapezeke. "

Zotsatira zoyipa za amlodipine ndi clarithromycin

Pogwiritsa ntchito nthawi yomweyo antibacterial othandizira, zotsatirapo zoyipa zingawonedwe:

• kusanza ndi kusanza
• chizungulire
• khungu loyipa
• matumbo dysbiosis,
• matenda oyamba ndi fungus,
• kusowa kwa vitamini.

Tulutsani mafomu ndi mtengo

Mitengo ya clarithromycin imatha kusiyanasiyana ndi wopanga:

• Mapiritsi
  • 250 mg, 14 ma PC. - 195 p,
  • 500 mg, 14 ma PC. - 200 - 590 r,
• Mapiritsi ogwira ntchito kwa nthawi yayitali 500 mg, 7 ma PC. - 380 - 400 r,
• Makapisozi 250 mg, 14 ma PC. - 590 p.

Mankhwala otchedwa "Amoxicillin" amapangidwanso ndi makampani osiyanasiyana (kuti zitheke, mitengo ya mapiritsi ndi makapisozi amaperekedwa molingana ndi ma pc a 20.):

• Kuyimitsidwa pakamwa makonzedwe a 250 mg / 5 ml, botolo la 100 ml - 90 r,
• Kuyimitsidwa kwa jakisoni 15%, 100 ml, 1 pc. - 420 r
• Makapiritsi / mapiritsi (apezekanso ma PC 20.):
  • 250 mg - 75 r,
  • 500 mg - 65 - 200 r,
  • 1000 mg - 275 p.

Kodi ndingatenge Clarithromycin ndi Amoxicillin nthawi imodzi?

Lingaliro la kaya pankhani inayake ndikotheka kutenga Clarithromycin ndi Amoxicillin palimodzi akuyenera kusankha payekhapayekha kwa wodwala aliyense. Chifukwa chaichi, matendawa ndi kuopsa kwa matendawa, kulekerera kwa mankhwala, omwe kale anali kuchitira maphunziro a antiulcer amakhazikitsidwa. Mwachitsanzo, ndi gastritis kapena zilonda zazing'ono zoyambira nthawi yoyamba, poganizira kupezeka kwa Helicobacter, kuphatikiza kwa mankhwalawa ndi koyenera.

Ngati zilonda zanu zili zazikulu, kapena kugwiritsa ntchito kale kwa mankhwalawa sikunapereke zotsatira zabwino, zitha kusintha ndikusakanikirana ndi De-nol + Tetracycline + Metronidazole. Mankhwalawa ali ndi mphamvu zambiri, koma mavuto ake amayambanso kukhala olimba.

Ngati wodwalayo salola Clarithromycin kapena Amoxicillin, mankhwalawa amaloledwa ndi Metronidazole. Kuphatikiza kotereku ndikofanana ndipo sizinganene kuti ndibwino.

Kodi hlalithromycin imagwira ntchito bwanji?

Awa ndi mankhwala opangidwa ndi theka omwe ali m'gulu la macrolide. Amakhala ndi antimicrobial, anti-kutupa ndi bacteriostatic katundu. Mankhwalawa amasokoneza kapangidwe ka protein mu cell yachilendo, kuletsa kukula ndi kubereka.

The yogwira mankhwala (clarithromycin) amatha kupanga ndende m'mimba kwambiri kuposa seramu yamagazi, chifukwa chake amagwiritsidwa ntchito kwambiri mu gastroenterology.

Gastritis

Ndi gastritis, njira yovomerezeka imasankhidwa ndi dokotala payekhapayekha.

Chiwembuchi chimaphatikizapo mankhwala atatu ndipo chikuwoneka motere:

1. Omeprazole (prostaglandin) - piritsi 1 (20) mg.
2. Amoxicillin - 1 kapisozi (1000 mg).
3. Clarithromycin - piritsi 1 (500) mg.

Tengani 2 pa tsiku kwa masiku 7-14. Prostaglandin iyenera kuledzera mphindi 20 asanadye, komanso maantibayotiki okhala ndi zakudya.

Zotsatira zoyipa za amoxicillin ndi clarithromycin

Nthawi zambiri, vuto la ma antimicrobial wothandizila lingayambitse zotsatirazi:

• nseru
• kusanza
• dysbiosis,
• thupi lawo siligwirizana monga zotupa pakhungu,
• chizungulire
• hypovitaminosis,
• kufooka kwa thupi.

Amoxicillin limodzi ndi ecthithromycin angayambitse mseru komanso kusanza.

Kuwonetsedwa kwa zotsatira zoyipa sikuti kukuwonetsa kuti uchotse mankhwala, muyenera kufunsa dokotala kuti akupatseni malangizo.

Momwe mungatengere nthawi yomweyo?

Pochiza zilonda zam'mimba, Amoxicillin amatengedwa 2 pa tsiku kwa 1000 mg, ndipo Clarithromycin 2 pa tsiku 500 mg. Njira ya mankhwala ayenera kukhala masiku 7. Chithandizo sichimayambitsa mavuto ambiri ndipo chalandira ndemanga zambiri kuchokera kwa odwala ndi madokotala. Itha kuchitika mu chipatala komanso paulendo wapaulendo.

Ngati zilonda zake zimachulukirachulukira, ndipo mankhwalawo sathandizira, njira zothetsera “zotaya chiyembekezo” ndizotheka. Muli poika Amoxicillin pa mlingo wa 3000 g tsiku lililonse kwa 2 mpaka 3 Mlingo kwa masiku 10 mpaka 14. Malangizo a mankhwalawa angayambitse mavuto ambiri ndipo amayenera kuchitika mchipatala.

Nkhaniyi ndi ya zidziwitso zokhazokha.

Osadzisilira. Musanagwiritse ntchito mankhwala aliwonse, onetsetsani kuonana ndi dokotala

Omeprazole, Amoxicillin, Clarithromycin

Kufanana ndi maantibayotiki, Omez (Omeprazole) amagwiritsidwa ntchito nthawi zonse, omwe amachepetsa acidity m'mimba, kusokoneza magwiridwe antchito a Helicobacter. Komanso, acidity yotsika, zilonda zam'mimba zimachira msanga ndipo maantibayotiki amatha kugwira ntchito mwachilungamo, osasweka.

Makina ochitapo kanthu a mankhwalawa amachokera pazolepheretsa khungu, zomwe zimatulutsa H + nthawi zonse m'mimba. Pakalibe ma hydrogen ions, ma chlorine ions Cl - sangathe kulumikizana ndi chilichonse ndipo, mwanjira yake, kupanga kwa hydrochloric acid (HCl) sikudzachitika. Zotsatira zake, chilengedwe cha acidic cham'mimba chimakhala chosalowerera.Helicobacter pylori amwalira m'malo osaloledwa komanso zamchere, zomwe zimathandizanso kuchira msanga.

Momwe mungatengere limodzi?

Malangizo a omez pophatikizika ndi ecithromycin ndi amoxicillin ndiosavuta. Omez amatengedwa asanagone mu mlingo wa 20 mg kwa masiku 7. Mankhwala onse atatuwa amamwa nthawi imodzi komanso maphunziro amodzi.

Ngati m'malo mwa clarithromycin ndi amoxicillin, regimen ya De-nol + Tetracycline + Metronidazole imagwiritsidwa ntchito, ndiye kuti Omez waledzera kale kawiri patsiku, 20 mg aliyense.