Matenda a shuga ndi chilichonse chokhudza izi

Pambuyo pokonzekera intravenous 200 mg ya alpha-lipoic (thioctic) acid, kuchuluka kwa plasma concentration (Cmax) kunali 7.3 μg / ml, nthawi yofika kwambiri (TCmax) inali 19 min, ndipo dera lomwe linali pansi pa nthawi yokhazikika (AUC) linali 2.2 2.2g / ml / ola. Pambuyo pokonzekera kulowetsedwa kwa thioctic acid pa mlingo wa 600 mg, Cmax anali 31.7 μg / ml, TCmax - 16 min, ndi AUC - 2.2 μg / ml / ola.
Thioctic acid imadutsa mphamvu yoyamba kudzera pachiwindi. Kapangidwe ka metabolites kumachitika chifukwa cha kupendekeka kwa mbali ndi oxidation. Hafu ya moyo ndi mphindi 25. Imapukusidwa ndi impso, 80-90%, makamaka mu mawonekedwe a metabolites.

Njira yogwiritsira ntchito

Mankhwala Tiogamm TurboPopeza adasakanizidwa kale ndi 50-250 ml ya 0,9% sodium chloride solution, amadzipaka jekeseni, pang'onopang'ono, osapitirira 50 mg pa mphindi imodzi, pa mlingo wa 600 mg (1 ampoule) patsiku, kwa masabata 2-4 tsiku lililonse.
Chifukwa cha chidwi cha ntchito yogwira popepuka, ma ampoules amayenera kuchotsedwa m'bokosilo nthawi yomweyo isanayambe. Njira yothetsera imayenera kutetezedwa ndikuwala.

Zotsatira zoyipa

Mukamagwiritsa ntchito mankhwalawa Tiogamm Turbo Zotsatira zoyipa monga: zokhudza zonse ziwopsezo, kufikisa kwa anaphylactic, urticaria kapena eczema pamalo opangira jakisoni, hemorrhagic rash (purpura), thrombophlebitis, chizungulire, thukuta, kupweteka kwa mutu komanso kusokonezeka kwa mashesa chifukwa cha kuchepa kwa shuga m'magazi, kuchuluka intracranial kukakamiza ndi dyspnea ndi mtsempha wa magazi kukhazikika, mseru, kusanza, kupweteka kwam'mimba, kutsegula m'mimba.
Si kawirikawiri: vuto la kukoma.

Zoyipa:
Contraindication kugwiritsa ntchito mankhwalawa Tiogamm Turbo ndi: hypersensitivity ku zigawo za mankhwala, zilonda zam'mimba, hyperacid gastritis, jaundice yayikulu yamtundu uliwonse wa etiology, mawonekedwe osokoneza bongo a shuga, pakati ndi kuyamwa, mwana ndi unyamata mpaka zaka 18.

Kuchita ndi mankhwala ena

Panali kuchepa kwa mphamvu ya chisplatin pamene idaperekedwa pamodzi Tiogamm Turbo. Mankhwala sayenera kutumikiridwa pamodzi ndi chitsulo, magnesium, potaziyamu, nthawi yapakati pakati Mlingo wa mankhwalawa iyenera kukhala osachepera maola asanu. Popeza kuchepa kwa shuga kwa insulin kapena mankhwala opatsirana pakamwa kungalimbikitsidwe, kuyang'anira shuga wamagazi ndikulimbikitsidwa, makamaka kumayambiriro kwa mankhwala ndi Tiogammma. Kupewa zizindikiro za hypoglycemia
ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magazi.

Bongo

Zizindikiro za kuledzera Tiogamm Turbo (zopitilira 6000 mg mwa munthu wamkulu kapena wopitilira 50 mg pa kilogalamu ya kulemera kwa mwana): kukomoka mwamphamvu, kusokonezeka kwakukulu kwa acid-base balance kumayambitsa lactic acidosis, kusokonezeka kwakukulu pakuphatikizika kwa magazi.
Chithandizo: Kugonekedwa kuchipatala mwachangu ndi njira zochizira zochotseredwa (kufooka kwa masanzi, kutsuka kwa m'mimba, makala oyatsidwa) kumasonyezedwa. Mankhwalawa ndi chizindikiro, palibe mankhwala enaake.

Kutulutsa Fomu

Tsatirani njira yothetsera kulowetsedwa, 30 mg / ml
20 ml ya mankhwalawa amaikidwa mu ma ampoules a galasi la bulauni.
Ma ampoules 5 amayikidwa mu katoni yamakatoni.

20 ml ya yankhoTiogamm Turbo muli ndi zinthu zomwe zimagwira - asidi a thioctic meglumine mchere - 1167.70 mg (womwe ndi wofanana ndi 600 mg thioctic acid).
Othandizira: meglumine, macrogol 300, madzi a jakisoni.

Zosankha

:
Pa mankhwala ndi mankhwala Tiogamm Turbo kumwa mowa kumapangidwa.
Zomwe zimapangitsa chidwi pakuyendetsa galimoto komanso njira zowopsa
Chifukwa cha zovuta zoyipa, chisamaliro chikuyenera kuthandizidwa poyendetsa magalimoto ndi makina owopsa.

Kutulutsa mafomu ndi kapangidwe kake

Biconvex, woyikidwa matuza a ma cell (ma PC 10). Paketi imodzi ili ndi matuza 10, 6 kapena 3. Mu granule imodzi ndi 0,6 g wa thioctic acid. Zinthu zina:

croscarmellose sodium
ma cellulose (pama microcrystals),
sodium lauryl sulfate,
macrogol 6000,
magnesium wakuba,
simethicone
hypopellose,
lactose monohydrate,
utoto E171.

Mankhwala Tiogamma amapezeka mu mawonekedwe a mapiritsi, ampoules ndi yankho.

Kugulitsidwa m'mabotolo agalasi. Mu paketi 1 amachokera 1 mpaka 10 ampoules. 1 ml ya kulowetsedwa njira lili ndendende 12 mg yogwira mankhwala (thioctic acid). Zinthu zina:

madzi a jakisoni
meglumine
macrogol 300.

Zotsatira za pharmacological

Gawo lomwe limagwiritsa ntchito mankhwalawa ndi antioxidant yogwira yomwe imatha kumanga ma free radicals. Alpha lipoic acid imapangidwa m'thupi mkati mwa decarboxylation ya alpha keto acid.

kuchuluka kwa glycogen,
amachepetsa magazi
kumathandiza kupewa insulin.

Malingana ndi mfundo yowonetsera, gawo lomwe limagwiritsa ntchito mankhwalawo limafanana ndi mavitamini B.

Imasinthasintha kagayidwe ka lipids ndi chakudya, imakhazikika pachiwindi komanso imathandizira kagayidwe ka cholesterol. Mankhwala ali:

hepatoprotective
achina,
hypocholesterolemic,
lipid-kutsitsa kwenikweni.

Amakonzanso zakudya zama neuron.

Contraindication

Contraindication wathunthu ukuphatikiza:

kusowa kwa mkaka,
mimba
mowa wamtundu
galactose chitetezo chokwanira
yoyamwitsa
galactose-glucose malabsorption,
wazaka 18
munthu tsankho kwa zomwe zikuchokera mankhwala.

Njira yayitali yauchidakwa ndikutsutsana ndi mankhwalawa.
Kugwiritsa ntchito mankhwala a Tiogamm pa nthawi ya pakati kumapangidwa.
Kuyamwitsa ndi imodzi mwazinthu zotsutsana ndi kugwiritsa ntchito mankhwala a Tiogamm.

Momwe angatenge

Njira yothetsera vutoli imaperekedwa kudzera m'mitsempha (iv). Wapakati tsiku ndi tsiku ndi 600 mg. Mankhwalawa amaperekedwa pakadutsa theka la ola kudzera mu dontho.

Mukachotsa botolo ndi mankhwalawo m'bokosilo, nthawi yomweyo limayikidwa mwapadera kuti liziteteza ku kuwala.

Kutalika kwa maphunziro a mankhwalawa kuyambira 2 mpaka 4 milungu. Ngati akupitiliza makonzedwe ake, ndiye kuti wodwala amapatsidwa mapiritsi.

Kumwa mankhwala a shuga

Mankhwalawa matenda a shuga mellitus, mankhwala omwe amagwiritsidwa ntchito amathandizira kufalikira kwa endoneural ndikuwonjezera kupanga kwa glutathione, ndikuwongolera magwiridwe antchito a mitsempha. Kwa odwala matenda ashuga, Mlingo wa mankhwalawa umasankhidwa payekha. Nthawi yomweyo, amawunika kuchuluka kwa shuga ndipo ngati kuli kotheka, amasankha Mlingo wa insulin.

Ndi matenda a shuga, Mlingo wa mankhwala a Tiogamma amasankhidwa payekha.

Ntchito mu cosmetology

Thioctic acid imagwiritsidwa ntchito kwambiri pamtundu wa cosmetology. Ndi thandizo lake mutha:

makwinya osalala,
chepetsa khungu.
kuthetsa zotsatira za ziphuphu zakumaso (post-ziphuphu),
kuchiritsa zipsera / zipsera
yikani khungu la nkhope.

Tiogamma imagwiritsidwa ntchito kwambiri pamtundu wa cosmetology.

Kuchokera ku chitetezo chamthupi

zokhudza zonse ziwengo
anaphylaxis (osowa kwambiri).

kutupa
kuyabwa
urticaria.

Mukamagwiritsa ntchito mankhwala a Tiogamm, zimayambitsa matupi amtundu wa kuyabwa ndizotheka.

Kuchita ndi mankhwala ena

Ndi kuphatikiza kwa alpha-lipoic acid wokhala ndi chisplatin, kugwira kwake ntchito kumachepa komanso magawo azinthu zomwe zimagwira zimasintha. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimamanga chitsulo ndi magnesium, chifukwa chake ziyenera kuphatikizidwa mosamala ndi mankhwala omwe ali ndi zinthu izi.

Mukaphatikiza mapiritsi ndi hypoglycemic ndi insulin, mphamvu yawo ya zamankhwala imachulukana kwambiri.

Mankhwalawa atha kusinthidwa ndi njira izi:

Lipoic acid
Thioctacid BV,
Mbale 300,
Tiolepta Turbo.

Alfa-lipoic (thioctic) acid wa shuga mellitus Zizindikiro za matenda ashuga mwa akazi

Madokotala Othandizira

Ivan Korenin, wazaka 50, migodi

Kugwiritsa generic antioxidant kanthu. Mungamveketse za kufunika kwake. Amasintha khungu ndikukhala bwino. Chachikulu ndikutsatira malangizowo, ndiye kuti sipadzakhala "zovuta".

Tamara Bogulnikova, wazaka 42, Novorossiysk

Mankhwala abwino komanso apamwamba kwambiri kwa anthu omwe ali ndi zotengera "zoyipa" zam'mimbamo ndi omwe akufuna kuchepetsa thupi. Mankhwala otchedwa antioxidant amawonedwa m'masiku oyamba. Zotsatira zoyipa ndizosowa ndipo zimagwirizanitsidwa kwambiri ndi ntchito yapakati komanso zotumphukira zamanjenje.

Sergey Tatarintsev, wazaka 48, Voronezh

Ndakhala ndikudwala matenda a shuga kwa nthawi yayitali. Posachedwa, kusasangalala kunayamba kuwoneka m'miyendo. Dokotalayo anakhazikitsa njira yochizira ndi mankhwalawa. M'masiku oyambilira, adaba jekeseni, kenako adotolo adandisuntsira mapiritsi. Zizindikiro zosasangalatsa zasowa, ndipo miyendo tsopano yatopa kwambiri. Ndimapitilizabe kumwa mankhwala pofuna kupewa.

Veronika Kobeleva, wazaka 45, Lipetsk

Agogo ali ndi matenda a shuga (mtundu 2). Miyezi ingapo yapitayo, miyendo inayamba kuchotsedwa. Kuti athetse vutoli, dokotala adapereka yankho la kulowetsedwa. Mkhalidwe wa wachibaleyo watukuka kwambiri. Tsopano iyenso amatha kupita kusitolo. Tipitilizabe kuthandizidwa.

Zizindikiro zogwiritsidwa ntchito

Thiogamma adalembedwa kuti athandize:

mitsempha kuwonongeka kwa matenda ashuga
matenda a chiwindi
kuwonongeka kwa mitsempha pamiyendo ya kudalira mowa,
poyizoni
zotumphukira ndi zomvera-motor polyneuropathy.

Mankhwalawa ali m'gulu la mankhwala amkati, omwe pama cellular amakhudzidwa ndi mafuta ndi chakudya chamaguluga.

Malangizo ogwiritsira ntchito

Thiogamm solution imayendetsedwa kudzera m'mitsempha kwa mphindi 30, osapitirira 1.7 ml kwa mphindi. Malinga ndi malangizo ogwiritsira ntchito, ndikofunikira kusakaniza zamkati za 1 ampoule ndi 50-20 ml ya sodium chloride ya sodium, kenako ndikuphimba ndi kesi yoteteza dzuwa. Gwiritsani ntchito pasanathe maola 6.

Njira yokhazikika yopangidwa ndi Tiogamm ya osiyira pansi amachotsedwa mu phukusi, yokutidwa ndi kesi yoteteza dzuwa. The kulowetsedwa ikuchitika kuchokera botolo. Maphunzirowa ndi milungu 2-4 (mtsogolomo, adokotala akhoza kukupatsani mapiritsi).

Bokosi la mapiritsi a Tiogamm lili ndi malangizo ogwiritsa ntchito. Tenga pamimba yopanda thukuta, madzi akumwa. Mlingo wa tsiku ndi tsiku ndi piritsi limodzi. Mankhwalawa kumatha masiku 30-60. Maphunzirowa mobwerezabwereza amaloledwa pambuyo pa miyezi 1.5-2.

Zolemba ntchito

Iyenera kuwongolera kuchuluka kwa shuga m'magazi, kusintha mlingo wa insulin ndi mankhwala ena. Gawo lokhala ndi piritsi limodzi ndi laling'ono kuposa 0.0041.

Thiogamm ndi mowa sizigwirizana. Ndi koletsedwa kumwa mowa pa mankhwala. Kupanda kutero, chithandizo chamankhwala chimachepa, neuropathy imayamba ndikupita patsogolo.

Pa chithandizo, amaloledwa kuyendetsa magalimoto ndi machitidwe owopsa, chifukwa kumveka bwino kwa masomphenya ndi chidwi sikuphwanyidwa.

Sizoletsedwa kuyika Tiogamma kwa amayi apakati komanso pakubala. Pali chiopsezo chosokoneza mwana. Ngati kuli kovuta kusiya mankhwalawa panthawi yoyamwitsa, kuyamwa kumayimitsidwa.

Ana ndi achinyamata ochepera zaka 18 sakusankhidwa ndi Thiogamm, chifukwa thioctic acid imakhudza kagayidwe.

Mankhwala amathandizidwa kuti muchepetse thupi, koma malinga ndi kukhalapo kwa zochitika zolimbitsa thupi komanso zakudya zochepa zopatsa mphamvu.

Muubwana

Mankhwala ndi oletsedwa kugwiritsidwa ntchito osakwana zaka 18. Ichi ndichifukwa cha kuchuluka kwa thioctic acid pa metabolism, komwe kumatha kubweretsa zotsatira zosalamulirika m'thupi mwa ana ndi achinyamata. Musanagwiritse ntchito, muyenera kufunsa dokotala nthawi zonse ndikupeza chilolezo pambuyo popenda bwino ziwalo ndi machitidwe.

Kukonzekera kwamankhwala kumapangidwa mosiyanasiyana kuti mugwiritse ntchito zochita za ana, chifukwa zotsatira zoyipa zimatha kukhala ndi zotsatira zoyipa, zomwe zimakhala zovuta kwambiri kuti ana asiye.

Zotsatira za mankhwala

Thiogamma ndi chida chomwe chimathandizira kukhazikika pamachitidwe a metabolic. Dziko lomwe lidachokera mankhwalawa ndi Germany. Amapangidwa monga:

mapiritsi
kulowetsedwa njira (mu dontho),
yang'anani pa kupanga njira yothetsera kulowetsedwa (jakisoni amapangidwa kuchokera ku ampoule).

Mapiritsiwo ali ndi chinthu chachikulu - thioctic acid, mu kulowetsedwa - mchere wa meglumine wa thioctic acid, komanso pakukhazikika kwa infusions - meglumine thioctate. Kuphatikiza apo, mtundu uliwonse wa mankhwalawo umakhala ndi zigawo zosiyanasiyana zothandizira.

Thioctic acid (dzina lachiwiri ndi alpha lipoic) ndi antioxidant wopangidwa mthupi. Imachepetsa shuga m'magazi ndikuwonjezera glycogen m'chiwindi, chomwe, chimapambana insulin. Kuphatikiza apo, thioctic acid imayang'anira kagayidwe ka lipids, chakudya ndi mafuta m'thupi. Amasintha ntchito ya chiwindi ndi trophic neurons, imathandizanso thupi la poyizoni. Ambiri, alpha lipoic acid ali ndi zotsatirazi:

hepatoprotective
kutsika kwa lipid,
hypocholesterolemic,
hypoglycemic.

Pochiza matenda a shuga, alpha-lipoic acid amakhala ndi magazi othamanga, amawonjezera kuchuluka kwa glutathione, chifukwa, pali kusintha kwa ntchito ya mitsempha ya mitsempha.

Thioctic acid imagwiritsidwa ntchito kwambiri popanga zodzikongoletsera: imasenda makwinya pankhope, imachepetsa kukhudzika kwa khungu, imachiritsa zipsera, komanso kufunafuna ziphuphu, ndikutsata pores.

Mitengo ndi kuwunika kwa mankhwala

Mtengo wa mankhwalawa umatengera mtundu wa kumasulidwa kwake. Chifukwa chake, mtengo wamapiritsi (zidutswa 30 za 600 mg) zimasiyana kuchokera ku 850 mpaka 960 rubles. Mtengo wa yankho la kulowetsedwa (botolo limodzi) ndikuchokera ku 195 mpaka 240 ma ruble, kutsata kwa kulowetsedwa kwamkati kuli pafupifupi ma ruble 230. Mutha kugula mankhwala pafupifupi mankhwala aliwonse.

Ndemanga za madotolo ndi odwala za mankhwala a Tiogamma ndi abwino. Mankhwalawa amatchuka kwambiri pochiza matenda ashuga komanso kupewa matenda a neuropathy. Madokotala ambiri amati simuyenera kuopa mndandanda waukulu wa zotsutsana ndi zoyipa. M'malo mwake, zovuta zoyipa zimachitika kawirikawiri - nthawi 1 pa milandu 10,000.

Potengera kuwunikira kwa ogwiritsa ntchito chida ichi, zabwino zotsatirazi zitha kusiyanitsidwa:

kugwiritsa ntchito mapiritsi, kamodzi kokha patsiku,
mfundo zamtengo wapatali,
yochepa maphunziro.

Madokotala nthawi zambiri amapereka mankhwala a Tiogamm mu mawonekedwe a njira yothetsera kulowetsedwa pansi povomerezeka. Mankhwalawa ali ndi chithandizo chamankhwala mwachangu ndipo kwenikweni samayambitsa mavuto.

Thiogamm amadziwikanso ngati chida chokongoletsera. Odwala ambiri amati mankhwalawa amathandiziradi makwinya.

Koma nthawi zina, zinthu zosagwirizana monga redness ndi kuyabwa ndizotheka.

Mndandanda wazomwezi mankhwala

Ngati wodwala salola mankhwalawa kapena ali ndi zovuta, kugwiritsa ntchito mankhwalawa kuyenera kusiyidwa.

Dokotala atha kukulemberani mankhwala ena omwe ali ndi thioctic acid, mwachitsanzo:

Thioctacid imagwiritsidwa ntchito makamaka pochiza matenda a neuropathy kapena polyneuropathy mu mawonekedwe osokoneza bongo a matenda osokoneza bongo. Mankhwalawa amasulidwa mwanjira ya mapiritsi ndikuzama.Mosiyana ndi Tiogamma, Thioctacid ali ndi zotsutsana zochepa, zomwe zimaphatikizapo nthawi yokhazikika, kuyamwitsa, ubwana komanso kusalolera payekha pazinthu zomwe zimagwiritsidwa ntchito ndi mankhwalawa. Mtengo wamankhwala mumapiritsi ndi pafupifupi ma ruble a 1805, ma ampoules a kulowetsedwa kwamkati - 1530 rubles.
Berlition imakhudza thupi la munthu, chifukwa imathandizira kagayidwe kazinthu, imathandizira kuyamwa mavitamini ndi michere, imakhazikika pamatumbo ndi mafuta kagayidwe, imapangitsa magwiridwe antchito a mitsempha. Mankhwala amamasulidwa mu mawonekedwe a ampoules ndi mapiritsi. Mtengo wapakati wa ma ampoules ndi ma ruble 570, mapiritsi - 765 rubles.
Lipothioxone ndi njira yolimbikitsira kulowetsedwa yomwe imagwiritsidwa ntchito mu matenda ashuga ndi mowa. Sitha kugwiritsidwa ntchito kwa ana ochepera zaka 6, ndipo panthawi yomwe muli ndi pakati, kugwiritsa ntchito mankhwalawa kumaloledwa ngati chithandiziro chitha kupitilira chiwopsezo kwa mwana wosabadwayo. Mtengo wapakati wa mankhwalawa ndi 464 rubles.
Oktolipen - mankhwala ogwiritsira ntchito kukana insulin, shuga wamagazi ambiri ndikuwonjezera glycogen m'chiwindi. Mankhwala amapezeka mu mawonekedwe a mapiritsi, makapisozi ndi magwiritsidwe ake a yankho. Mtengo wapakati wa mankhwalawa m'mapiritsi ndi 315 ma ruble, mapiritsi - 658 ma ruble, ma ampoules - 393 ma ruble. Oktolipen wa mtundu wa 2 matenda a shuga amatha kuphatikizidwa bwino ndi metformin ndi othandizira ena a hypoglycemic.

Kutengera ndi zotsutsana ndi kuthekera kwachuma, wodwalayo amapatsidwa mwayi wosankha njira yabwino kwambiri yomwe ingakhale yothandiza pochiritsa.

Ndipo, motero, Thiogamma ndi mankhwala othandiza pochiritsa matenda a shuga ndi matenda ena oopsa. Zake zogwira ntchito, thioctic acid, zimakhudza kagayidwe ka mafuta ndi chakudya, zimachepetsa kuchuluka kwa glucose m'magazi, zimawonjezera zomwe zili mu chiwindi komanso kumverera kwa zotumphukira kwa insulin. Mankhwalawa amapezeka m'njira zingapo. Mukamagwiritsa ntchito mankhwalawa, muyenera kutsatira malangizo a dokotala, chifukwa nthawi zambiri zimachitika zovuta kupewa. Kwenikweni, chida chikuyankhidwa, kotero chitha kugwiritsidwa ntchito mosazungulira kuti magwiridwe antchito amanjenje athe.

Phindu la lipoic acid a matenda a shuga afotokozedwa mu kanema munkhaniyi.

Zotsatira za pharmacological

Chofunikira chachikulu pakupanga mankhwala a Tiogamm, mosasamala mawonekedwe a kumasulidwa thioctickapena alpha lipoic acid (mayina awiri a chinthu chomwecho cha biological yogwira). Ichi ndi gawo lachilengedwe la kagayidwe, ndiye kuti acid zambiri zimapangidwa mthupi ndipo zimachitika coenzyme wa mitochondrial maofesi mphamvu kagayidwe ka pyruvic acid ndi alpha-keto acid munjira ya oxidative decarboxylation. Thioctic acid ndi amkati. antioxidant, popeza imatha kumanga ma radicals aulere komanso kuteteza maselo kuti asawonongeke motere.

Udindo wa gawo la mankhwala ndiwofunikanso chakudya kagayidwe kachakudya. Zimathandizira kuchepetsa kufalikira kwa glucose momasuka mu seramu yamagazi ndi kuchuluka kwa glycogen m'maselo a chiwindi. Chifukwa cha nyumbayi, thioctic acid imachepetsa insulin kukana maselo, ndiko kuti, kuyankha kwakuthengo kwa mahomoni awa kumagwira ntchito kwambiri.

Analowa Malangizo a lipid metabolism. Zomwe zimagwiritsidwa ntchito pa metabolism zimadziwika kwambiri. cholesterol monga hypocholesterolemic wothandizila - asidi amachepetsa kufalikira kwa otsika kwambiri komanso osachulukitsa kwambiri a lipids ndipo kuchuluka kwa milomo yapamwamba kwambiri m'mitsempha yamagazi kumawonjezeka). Ndiye kuti, thioctic acid ali ndi zina antiatherogenic katundu ndipo amatsuka bedi yaying'ono- ndi macrocirculatory yamafuta ochulukirapo.

Zotsatira zakusintha kukonzekera kwa mankhwala kumawonekeranso ngati pakachitika poyizoni wokhala ndi mchere wambiri wazitsulo ndi mitundu ina kuledzera. Kuchita izi kumachitika chifukwa cha kutseguka kwa njira mu chiwindi, chifukwa chake ntchito yake imayenda bwino. Komabe, asidi wa thioctic samathandizira kutopa kwake. hepatoprotective katundu.

Tiyenera kudziwa kuti mankhwala okhala ndi alpha-lipoic acid amagwiritsidwa ntchito mwachangu matenda ashuga, popeza opangidwawo amathandizira kuchepetsa mapangidwe a glycation metabolites ndikuwonjezera zomwe zili glutathione kwa maulalo a thupi. Komanso misempha yama trophic imakhala bwino ndi endoneural magazi, omwe amatsogolera kukuwonjezeka kwakukulu mu boma la zotupa zamitsempha yamagetsi ndikuletsa kukula kwa matenda ashuga polyneuropathy (gawo la nosological lomwe limayamba chifukwa cha kuwonongeka kwa mizere ya mitsempha chifukwa cha kuchuluka kwa glucose ndi metabolites).

Mu mankhwala ake a hepato- ndi neuroprotective, detoxization, antioxidant, hypoglycemic ndi ena ambiri) thioctic acid ndi ofanana mavitaminiGulu B.

Thioctic kapena alpha lipoic acid yatchuka kwambiri mu cosmetologychifukwa cha kutsatira kwa pharmacological khungu la nkhope, zomwe nthawi zambiri zimakhala zovuta kusamalira:

kunyamuka Hypersensitivity,
kulimbitsa khungu lanu amachepetsa makwinyakuwapanga kukhala osawoneka ngakhale m'malo ovuta monga ngodya zamaso ndi milomo,
amachiritsa zizindikiro ziphuphu (ziphuphu) ndipo zipsera, popeza, kulowa mkati mwa zinthu zomwe zimapangidwira, kumapangitsa kuti magwiridwe antchito apangidwe mobwerezabwereza,
amalimbitsa pores pankhope ndikuyang'anira luso lantchito zotupa za sebaceouspotero kuthetsa mavuto a khungu lamafuta kapena mafuta.
amachita ngati antioxidant wamphamvu wa amkachokera.

Pharmacodynamics ndi pharmacokinetics

At makamwa Mankhwala mwachangu komanso odziwikiratu kuchokera kumimba. Tiyenera kudziwa kuti kugwiritsa ntchito mankhwalawa pamodzi ndi chakudya kumachepetsa kuyamwa kwa Thiogamma. Pambuyo pa gawo loyamba kudzera m'chiwindi, gawo lalikulu la gawo lofunikalo limasinthika mosasintha (mu mabuku a pharmacological izi zimatchulidwa kuti yoyamba kudutsa zotsatira), chifukwa mankhwalawa a bioavailability amachokera pa 30 mpaka 60 peresenti, kutengera mphamvu ya thupi. Kuchuluka kwa plasma ndende kuli pafupifupi 4 μg / ml ndikutulutsa kwamphindi 30.

Thiogma kwa otsitsira kapena kukonzekera kulowetsedwa kumayendetsedwa kudzera mu mankhwalawa, motero, kukonzekera kwamankhwala mumtunduwu wamasulidwe kumatha kupewa zovuta za gawo loyambalo. Nthawi yobereka mu kayendedwe kazinthu zimakhala pafupifupi mphindi 10-11, ndipo kuchuluka kwakukulu kwa plasma pamenepa ndi 20 μg / ml.

Wopangidwira mankhwala, ngakhale mawonekedwemu chiwindi ndi makutidwe ndi okosijeni am'mbali ndi kuphatikizika kwina. Chilolezo cha Plasma - 10-15 ml / min. Thioctic acid ndi zinthu zake zama metabolic akuwonetsedwamakamaka impso(pafupifupi 80-90 peresenti). Mu mkodzo, gawo lochepa la zosintha zamankhwala limapezeka. Hafu ya moyo wa mankhwalawa Tiogamm 600 (nambala 600 imawonetsa kuchuluka kwa alpha-lipoic acid malinga ndi zomwe zatsalira) ndi mphindi 25, ndipo mtundu wowonjezereka wa mankhwala wotchedwa Tiogamm Turbo - kuyambira 10 mpaka 20 mphindi.

Thiogamma, malangizo ogwiritsira ntchito (Njira ndi Mlingo)

Malangizo ogwiritsira ntchito Thiogamm amasiyanasiyana malinga ndi mtundu wa mankhwala omwe mumagwiritsidwa ntchito.

Mapiritsi a 600 mg Kugwiritsa pakamwa kamodzi patsiku. Osamawataya, popeza chipolopolo chitha kuwonongeka, tikulimbikitsidwa kuti mumwe ndi madzi ochepa. Kutalika kwa maphunzirowa kumatchulidwa ndi dokotala wokhazikika, chifukwa zimatengera kuchuluka kwa matendawo. Nthawi zambiri mapiritsi amatengedwa kuchokera masiku 30 mpaka 60. Kubwereza maphunziro othandizira olimbitsa thupi ndizotheka katatu pachaka.

Tiogamm Turbo ntchito kwa makolo makonzedwe a mtsempha wa magazi kukapanda kuleka kulowetsedwa. Mlingo wa tsiku ndi tsiku ndi 600 mg 1 nthawi patsiku - wowerengeka pazomwe zili m'botolo imodzi kapena wokwanira. Kumayambiriro kumachitika pang'onopang'ono, kopitilira mphindi 20-30, kuti mupewe zotsatira zoyipa kuchokera pakulowetsedwa kwa mankhwala. Njira ya mankhwala a mankhwalawa imachokera ku milungu iwiri mpaka inayi (kufupikitsika kwa nthawi yodziwikiratu chithandizo kumachitika chifukwa cha kuchuluka kwa plasma ndende pambuyo pa utsogoleri waudokotala).

Gwiritsani ntchito kukonzekera kulowetsedwa kwamitsempha Gwiritsani ntchito motere: zomwe zili mu 1 ampoule (malinga ndi chophatikizira chachikulu - 600 mg wa thioctic acid) zimaphatikizidwa ndi 50-250 isotonic (0,9%) yankho la sodium chloride. Atangomaliza kupangira mankhwalawa, botolo limakutidwa ndi vuto loteteza (mosalephera, pamakhala piritsi limodzi pakukonzekera mankhwala). Nthawi yomweyo, yankho limaperekedwa ndi kulowetsedwa kwa kulowetsedwa kwa mphindi 20-30. Nthawi yayikulu yosungirako yothetsera Tiogamm yotsala sinaposa maola 6.

Thiogamma imagwiritsidwa ntchito posamalira khungu. Kuti muchite izi, gwiritsani ntchito mankhwala mawonekedwe a otsikira Mbale (ma ampoules omwe amakhala ndi chidwi chokhazikitsira kulowetsedwa kwa intravenous sioyenera monga chinthu chodzikongoletsa, chifukwa amatha kuyambitsa zovuta chifukwa chifukwa cha kuchuluka kwa gawo lomwe limagwira. Zomwe zili m'botolo limodzi zimayikidwa pakhungu loyera pakhungu kawiri pa tsiku - m'mawa ndi madzulo. Pamaso pa kunyengedwa kotereku, tikulimbikitsidwa kusamba ndi madzi ofunda, a sopo kuti muyeretse pachipata cha ma pores kuti mulowetse kwambiri thioctic acid.

Malangizo apadera

Kukonzekera kwa mankhwala kungagwiritsidwe ntchito ngati chodzikongoletsera kusamalira khungu la nkhope. Zogwira ntchito zimakhala ndi mphamvu ya antioxidant ndipo sizikhala ndi mphamvu yochepa yamphamvu, chifukwa Thiogamma ya nkhope yatchuka kwambiri mu cosmetology yodziwikiratu ngati kukweza tonic. Momwe mungagwiritsire ntchito Thiogamm pakhungu la peeling mungapezeke pazotsatira zamankhwala.

Kuchiza ndi mankhwala opangira mankhwalawa sikukukhudza chidwi chambiri kapena kwa nthawi yayitali. Chifukwa chake kuyendetsa galimoto kapena kugwira ntchito ndi zinthu zina zomwe zimakhala zoopsa kwa moyo sikuletsedwa panthawi yopanga mankhwala.

Zolemba za Thiogamma

Mapulogalamu a Thiogma amapanga gulu lalikulu la mankhwala, chifukwa zochizira zomwe zaperekedwa tsopano ndizodziwika kwambiri. Ndiosavuta kugwiritsa ntchito mankhwalawa kupewa matenda amitsempha yayikulu kuposa kuwachiritsa pambuyo pake ndi njira yolephera, ndikuyenda mankhwala osokoneza bongo kwa nthawi yayitali. Chifukwa chake limodzi ndi a Tiogamma amagwiritsidwa ntchito: Berlition 300, Neuro liponendi Oktolipen.

Ndemanga za Tiogamma

Mankhwala omwe amapezeka ndizotchuka kwambiri kwa odwala matenda ashuga kapena kulosera kwa mitsempha. Popeza Thiogamma amapereka prophylactic chithandizo cha matenda a zotumphukira zamitsempha ndipo samalola kulumala kwazaka zambiri. Chifukwa cha njira yocheperako, mutha kudziteteza ku zotsatira zoyipa kwambiri endocrine matenda.

Anthu omwe adagwiritsa ntchito mankhwalawa padera amadziwa kuti simuyenera kuchita mantha ndi zovuta zingapo, chifukwa kuchuluka kwake, ngakhale malinga ndi mankhwala a World Health Association, amadziwika kuti ndi osowa kwambiri (zotsatira zosafunikira zamankhwala zimachitika mu milandu yopanda 1/10000 yokhudza zovuta zowonongeka) , kuphatikizapo kukomoka kwa episodic).

Odziwa kupita ku madotolo komanso akatswiri azamankhwala omwe ali ndi maphunziro amasangalatsidwa ndi Tiogamm, chifukwa chake amawagwiritsa ntchito kuchipatala. Chifukwa cha gawo loyambalo, mwayi wa mankhwala ochulukirapo kapena kuchuluka kwa zinthu zomwe zimagwira m'magazi amachepetsedwa, ndipo kawirikawiri zovuta zomwe zimachitika zimayimitsidwa mwachangu komanso mosavuta. Poyerekeza ndi zomwe zalembedwazi, momwe mankhwalawa amathandizidwira ndizodabwitsa, komwe ndi lingaliro labwino ngakhale pakati pa ogwira ntchito zachipatala.

Monga chodzikongoletsera chamaso, ndemanga za Tiogamm zimatsimikizira mbiri ya mankhwalawa. Thioctic acid imatha kulimbana ndi makwinya m'malo ovuta kwambiri amaso ndipo izi zimatsimikiziridwa ndikuthokoza kosawerengeka pamapulogalamu osamalira khungu. Komabe, pali kukhalanso kwa khungu lomwe siligwirizana ndi anthu omwe ali ndi chiyembekezo chotere (hypersensitivity kapena cholowa cholowa), motero, tikulimbikitsidwa kuti kuyezetsa Matupi musanagwiritse ntchito Thiogamm.

Mtengo wa Thiogamm, kuti mugule

Mtengo wa Tiogamma 600 mg zimatengera mtundu wa kumasulidwa kwa mankhwala, onse ku Russian Federation ndi ku Ukraine:

mapiritsi - kuchokera ku 800 mpaka 1000 rubles / 270-300 hryvnia phukusi lililonse,
Tiogamm Turbo - 1000-1200 ma ruble / 540-650 h pantnias,
ma ampoules okhala ndi yankho la makolo - ma ruble 190 (mtengo wa ampoule umodzi) / 640-680 h pantnias (mtengo pa phukusi),
madzimadzi otayaanafuna kulowetsedwa kudzera m'mitsempha - ma ruble 210 (pa botolo) / 72 hhucnias (mtengo wa gawo limodzi la mankhwala).

Pa mimba ndi mkaka wa m`mawere

Chifukwa cha zomwe zili pazinthu zomwe zikugwira, kugwiritsidwa ntchito kwa Thiogamma panthawi yoyembekezera komanso mkaka wa m'mawere ndizoletsedwa. Izi zimalumikizidwa ndi chiwopsezo chachikulu cha kugwira ntchito kwa mwana wosabadwayo ndikukula kwa khanda kapena khanda. Ngati nkosatheka kuletsa kugwiritsa ntchito mankhwalawa panthawi yoyamwa, ndiye kuti muyenera kusiya kapena kusiya kuyamwitsa kuti musavulaze mwana.

Pa mkaka wa m`mawere ndi pakati, kugwiritsa ntchito mankhwalawa contraindified chifukwa zotheka zimakhudza mwana.

Kuyanjana kwa mankhwala osokoneza bongo

Thioctic acid monga gawo la Thiogamma timapitiriza mphamvu ya anti-yotupa ya glucocorticosteroids. Zitsanzo zina za kugwiritsa ntchito mankhwala:

Chidachi chimachepetsa mphamvu ya Cisplatin.
Zomwe zimagwiritsidwa ntchito zimamanga zitsulo, kotero, kugwiritsa ntchito chitsulo, calcium ndi magnesium kukonzekera ndizoletsedwa - osachepera maola awiri azigwiritsa ntchito mankhwalawa.
Mankhwalawa amalimbikitsa zochitika za insulin, pakamwa za hypoglycemic.
Ethanol yokhala ndi metabolites imafooketsa mphamvu ya asidi.

Kupanga ndi mawonekedwe a kumasulidwa

Thioctic Acid 600mg

Hypromellose, colloidal silicon dioxide, cellcrystalline cellulose, lactose monohydrate, sodium carmellose, talc, simethicone, magnesium stearate, macrogol 6000, sodium lauryl sulfate

Meglumine thioctate (wofanana ndi 600 mg wa thioctic acid)

Macrogol 300, meglumine, madzi

Mapiritsi a Thiogamm

Mapiritsi amatengedwa kamodzi patsiku musanadye ndi Mlingo womwe adafotokozeredwa ndi adotolo, mapiritsiwo samatsalidwa ndikusambitsidwa ndi madzi pang'ono. Kutalika kwa maphunzirowa ndi masiku 30-60 ndipo zimatengera kuopsa kwa matendawa. Kubwereza zamankhwala ndizovomerezeka kuchita kawiri kapena katatu pachaka.

Thiogma kwa otsitsira

Mukamagwiritsa ntchito mankhwalawa, ndikofunika kukumbukira kugwiritsa ntchito vuto loteteza mopepuka mutachotsa botolo m'bokosi. Kulowetsedwa kuyenera kuchitidwa, kuwona jekeseni wa 1.7 ml pa mphindi.

Ndi mtsempha wamkati, amafunika kuti azitha kuyenda pang'onopang'ono (mphindi 30), mlingo wa 600 mg patsiku. Njira ya mankhwala ndi milungu iwiri kapena inayi, pambuyo pake amaloledwa kutalika kwa mankhwalawa pakamwa pakamwa piritsi limodzi la 600 mg.

Kwa khungu

matenda a shuga
kuwonongeka kwa mowa ku misempha yamitsempha,
matenda a chiwindi - hepatitis ndi matenda enaake osiyanasiyana, mafuta achulukidwe a hepatocytes,
zotumphukira kapena sensory-motor polyneuropathy,
kuledzera ndi mawonekedwe amphamvu (mwachitsanzo, mchere wa zitsulo kapena bowa).

Malangizo ogwiritsira ntchito Thiogamm amasiyanasiyana malinga ndi mtundu wa mankhwala omwe mumagwiritsidwa ntchito.

Mapiritsi a 600 mg amaperekedwa pakamwa kamodzi patsiku. Osamawataya, popeza chipolopolo chitha kuwonongeka, tikulimbikitsidwa kuti mumwe ndi madzi ochepa. Kutalika kwa maphunzirowa kumatchulidwa ndi dokotala wokhazikika, chifukwa zimatengera kuchuluka kwa matendawo. Nthawi zambiri mapiritsi amatengedwa kuchokera masiku 30 mpaka 60. Kubwereza maphunziro othandizira olimbitsa thupi ndizotheka katatu pachaka.

Thiogamm Turbo imagwiritsidwa ntchito popanga utsogoleri wa ana mwa kulowetsedwa mwa kulowerera. Mlingo wa tsiku ndi tsiku ndi 600 mg 1 nthawi patsiku - wowerengeka pazomwe zili m'botolo imodzi kapena wokwanira.

Kumayambiriro kumachitika pang'onopang'ono, kopitilira mphindi 20-30, kuti mupewe zotsatira zoyipa kuchokera pakulowetsedwa kwa mankhwala. Njira ya mankhwala a mankhwalawa imachokera ku milungu iwiri mpaka inayi (kufupikitsika kwa nthawi yodziwikiratu chithandizo kumachitika chifukwa cha kuchuluka kwa plasma ndende pambuyo pa utsogoleri waudokotala).

Zomwe zimapangidwira pakukonzekera kulowetsedwa kwa mtsempha wa mankhwalawa zimagwiritsidwa ntchito motere: zomwe zili mu 1 ampoule (malinga ndi chophatikizira chachikulu - 600 mg wa thioctic acid) zimaphatikizidwa ndi 50-250 isotonic (0,9 peresenti) yankho la sodium chloride.

Atangomaliza kupangira mankhwalawa, botolo limakutidwa ndi vuto loteteza (mosalephera, pamakhala piritsi limodzi pakukonzekera mankhwala).

Nthawi yomweyo, yankho limaperekedwa ndi kulowetsedwa kwa kulowetsedwa kwa mphindi 20-30. Nthawi yayikulu yosungirako yothetsera Tiogamm yotsala sinaposa maola 6.

Mankhwala ndi njira yowongolera chakudya chamafuta, lipid metabolism m'thupi la munthu.

Gawani m'milandu yotere:

ndi matenda a shuga
matenda osiyanasiyana a chiwindi (mitundu yonse ya hepatitis, cirrhosis, kuchepa kwamafuta kwa hepatocytes),
kuwonongeka kwa mitsempha
kuledzera kwa thupi, kumakwiyitsidwa ndi kuchuluka kwa bowa, mchere wamchere ndi zinthu zina.

Zofunika! Osamachita mankhwala omwe mumadzipangira nokha, onetsetsani kuti mukumane ndi dokotala musanamwe mankhwalawo.

Ndemanga za Odwala

Alla, wazaka 37. Mankhwala Tiogamm adandiwuza ndi mzanga amene adachepetsa thupi kuposa kuzindikira. Anatenga ndi chilolezo cha adotolo, ataphunzitsidwa, kuwonjezera pazakudya. Ndinayamba kumwa mapiritsi ndikudya momwemo, kwa mwezi umodzi ndinataya ma kilogalamu asanu. Zabwino kwambiri, ndikuganiza kuti ndibwereza maphunzirowa koposa kamodzi.

Alexey, wazaka 42. Malinga ndi zakumwa zakumwa zoledzeretsa, ndinayamba polyneuropathy, manja anga anali kugwedezeka, ndinayamba kuvutika ndimaganizo pafupipafupi. Madotolo adati tiyenera choyamba kuchiza uchidakwa, ndikuchotsa zotsatirapo zake. Pa gawo lachiwiri la zamankhwala, ndidayamba kumwa njira ya Tiogamma. Amathana bwino ndi vuto la neuropathy, ndidayamba kugona bwino.

Olga, wazaka 56 ndimadwala matenda a shuga, motero ndimakonda kuchita neuropathy. Madokotala adalemba Tiogamm kuti akhale ndi prophylaxis, komanso kusintha kwa insulin. Ndimamwa mapiritsi molingana ndi malangizo ndikuwona kusintha - ndakhala wodekha, sindikhala ndi nkhawa usiku komanso m'mawa, manja anga samagwedezeka chifukwa cha nkhawa.

Mankhwala ogulitsa mankhwalawa ndi otchuka kwambiri kwa odwala omwe ali ndi matenda osokoneza bongo kapena chiwopsezo cha neuropathies. Popeza Thiogamma amapereka prophylactic chithandizo cha matenda a zotumphukira zamitsempha ndipo samalola kulumala kwazaka zambiri.

Chifukwa chochepa kwambiri, mutha kudziteteza ku zotsatira zoyipa kwambiri za endocrine pathology.

Amayankha mankhwalawo nthawi zambiri mosakayikira. Anthu omwe ali ndi matenda ashuga amasangalala kwambiri.

Asayansi akuti kutenga Tiogamma popewa kupewa sikungachitike, koma kuwonetsa mavuto ndi manjenje, mankhwalawa amabweretsa mpumulo woonekera kwa odwala.

Maphunziro okhazikika amathandizira odwala, moyo wawo.