Victoza wa matenda ashuga

Masiku ano, imodzi mwa mankhwala odziwika bwino ndi Liraglutide pochiza matenda a shuga a mtundu 2.

Zachidziwikire, m'dziko lathu lapeza kutchuka posachedwa. Izi zisanachitike, zidagwiritsidwa ntchito kwambiri ku United States, komwe zakhala zikugwiritsidwa ntchito kuyambira zikwi ziwiri ndi zisanu ndi zinayi. Cholinga chake chachikulu ndikuthandizira odwala mopitirira muyeso. Koma kupatula izi, imagwiritsidwanso ntchito pochiza matenda ashuga, ndipo monga mukudziwa, ndi matenda a shuga 2, vuto ngati kunenepa kwambiri ndilofala kwambiri.

Kugwiritsa ntchito kwambiri mankhwalawa kumatheka chifukwa cha zinthu zapadera zomwe zimapanga kapangidwe kake. Mwakutero, ndi Lyraglutide. Ndi mndandanda wokwanira wa enzyme ya munthu, yomwe ili ndi dzina loti glucagon-like peptide-1, yomwe imakhala ndi mphamvu yayitali.

Chipangizochi ndi chithunzi chopanga cha munthu, motero chimagwira ntchito yake mthupi, chifukwa sikuti chimasiyanitsa komwe kuli analogue komwe kuli komanso komwe enzyme ili.

Mankhwalawa amagulitsidwa m'njira yothetsera jakisoni.

Ngati tikulankhula za kuchuluka kwa mankhwalawa, ndiye choyamba, mtengo wake umatengera mlingo wa chinthu chachikulu. Mtengo umasiyana kuchokera ku 9000 mpaka 27000 rubles. Kuti mumvetsetse kuchuluka kwa mankhwalawa omwe muyenera kugula, muyenera kuphunzira malongosoledwe a mankhwalawo pasadakhale, ndipo, onani, dokotala.

Pharmacological zochita za mankhwala

Monga tafotokozera pamwambapa, mankhwalawa ndi mankhwala abwino kwambiri odwala matenda a shuga, komanso amathandizanso kuchepetsa kunenepa kwambiri, komwe nthawi zambiri kumakhudza odwala omwe amapezeka ndi matenda a shuga a 2.

Izi ndizotheka chifukwa choti kulowa m'magazi a wodwalayo, mankhwalawo amakulitsa kwambiri ma peptides omwe ali mthupi la munthu aliyense. Ndi chochita ichi chomwe chimathandizira kapangidwe kake ka kapamba ndi kuyambitsa njira yopanga insulin.

Chifukwa cha njirayi, kuchuluka kwa shuga komwe kumakhala m'magazi a wodwalayo kumatsitsidwa kufikira mulingo womwe mukufuna. Momwemo, zinthu zonse zopindulitsa zomwe zimalowa m'thupi la wodwala limodzi ndi chakudya zimamwa bwino. Zotsatira zake, chifukwa chake, wodwalayo amalimbitsa thupi komanso kusadya.

Koma, monga mankhwala ena aliwonse, Liraglutid amayenera kumwedwa mosamala malinga ndi zomwe adokotala amapeza. Tiyerekeze kuti simuyenera kungogwiritsa ntchito chabe kuti muchepetse kunenepa. Njira yabwino kwambiri yothetsera vutoli ndi kugwiritsa ntchito mankhwalawa pamaso pa matenda a shuga a mtundu wachiwiri, omwe amaphatikizidwa ndi kunenepa kwambiri.

Mankhwala a Liraglutide atha kutengedwa ngati mukufuna kubwezeretsa index ya glycemic.

Koma madotolo amasiyananso ndi zizindikilo zotere zomwe zikusonyeza kuti wodwalayo samalimbikitsidwa kupereka mankhwala omwe atchulidwawa. Izi ndi:

• thupi lawo siligwirizana ndi mbali iliyonse ya mankhwala,
• kuzindikira kwa matenda a shuga 1
• matenda aliwonse a chiwindi kapena impso,
• kulephera kwamtima kwamadigiri atatu kapena anayi,
• zotupa m'matumbo,
• kupezeka kwa neoplasm pakhungu la chithokomiro,
• kukhalapo kwa angapo endocrine neoplasia,
• nthawi ya pakati mwa mayi, komanso yoyamwitsa.

Mukumbukiranso kuti mankhwalawa sayenera kumwa ndi jakisoni wa insulin kapena mankhwala ena aliwonse omwe ali ndi zigawo zomwezo. Madokotala samalangizabe kugwiritsa ntchito mankhwalawa kwa odwala omwe ali ndi zaka zopitilira 75, komanso kwa iwo omwe akupezeka ndi kapamba.

Victoza - mankhwala atsopano pochizira matenda a shuga a 2

Wopweteka - wothandizira wa hypoglycemic, ndi yankho la jakisoni mu cholembera cha 3 ml. The yogwira mankhwala a Viktoza ndi liraglutide. Mankhwalawa amagwiritsidwa ntchito limodzi ndi chithandizo chamankhwala komanso zochitika zolimbitsa thupi kwa odwala omwe ali ndi mtundu wa 2 matenda a shuga kuti akwaniritse standardoglycemia. Viktoza amagwiritsidwa ntchito ngati mankhwala osokoneza bongo pakumwa mankhwala ochepetsa shuga, monga metformin, sulfaureas kapena thiazolidinediones.

Chithandizo chimayamba ndi mlingo wochepa wa 0,6 mg, pang'onopang'ono kuwonjezeka kawiri kapena katatu, kufikira 1.8 mg patsiku. Mlingo uyenera kuchuluka pang'onopang'ono, kupitilira sabata imodzi kapena ziwiri. Kugwiritsa ntchito Victoza sikulepheretsa kugwiritsa ntchito mankhwala ochepetsa shuga, omwe amayambitsidwa pamankhwala omwe mumakhala nawo, ndikuwunika kuchuluka kwa shuga m'magazi kuti mupewe hypoglycemia mukamakonzekera sulfaurea. Ngati pali milandu ya hypoglycemia, kukonzekera kwa sulfaurea kuyenera kuchepetsedwa.

Victoza amathandizira kuchepetsa kuchepa kwa thupi, amachepetsa masanjidwe am'mimba amachepetsa, amachepetsa njala, amathandizira kuchepetsa kuthamanga kwa glucose komanso kutsika shuga m'magazi (shuga) atatha kudya. Kugwiritsa ntchito mankhwalawa kumapangitsa ntchito ya pancreatic beta cell. Mankhwala amakhudza kuthamanga kwa magazi, kumachepetsa pang'ono.

Victoza, ngati mankhwala aliwonse, ali nawo zingapo zoyipa:

zotheka za hypoglycemia, kuchepa kwa chakudya, kudzimbidwa, mseru, kusanza, kutsegula m'mimba, kudzimbidwa, kuchuluka kwa mpweya, kupweteka mutu

Zisonyezo za kutenga Victoza - mtundu 2 matenda a shuga.

Malangizo a Victoza:

Hypersensitivity mtundu wa 1 matenda a shuga aimpso ndi chiwindi ntchito anthu osakwana zaka 18 zakubadwa pakati ndi mkaka wa m`mawere

Mankhwalawa amayenera kusungidwa m'malo ozizira amdima pa kutentha kwa madigiri 2-8. Sayenera kuzizira. Cholembera chotseguka chimayenera kugwiritsidwa ntchito patatha mwezi umodzi, nthawi imeneyi ipangidwe cholembera chatsopano.

Victoza (liraglutide): wavomerezedwa kuti azigwiritsidwa ntchito mu matenda a shuga a 2

Kampani yopanga mankhwala Novo-Nordik, yomwe ikupanga mankhwala atsopano a insulin, yalengeza kuti yalandira chilolezo chalamulo chogwiritsa ntchito mankhwalawa kuchokera ku European Medicines Agency (EMEA).

Awa ndi mankhwala omwe amatchedwa Victoza, omwe cholinga chake ndi kuchiza matenda a shuga 2 mwa akuluakulu. Chilolezo chogwiritsa ntchito uthengawu chapezeka m'maiko 27 - mamembala a European Union.

Victoza (liraglutide) ndi mankhwala okhawo amtundu wake omwe amatsanzira ntchito ya mahomoni achilengedwe GLP-1 ndipo imapereka njira yatsopano yothandizira matenda a matenda ashuga a 2 kale gawo loyambirira la matendawa.

Njira yakuchiritsira, kutengera zochita za mahomoni achilengedwe GLP-1, imatsegula mwayi watsopano ndikuthandizira chiyembekezo chachikulu, malinga ndi Novo-Nordik. Horoni GLP-1 imasungidwa m'thupi la munthu ndi maselo a m'matumbo panthawi yotsekula chakudya ndikuchita gawo lofunikira mu metabolism, makamaka kugwiritsidwa ntchito kwa shuga.

Kudya chakudya kuchokera m'mimba kupita m'matumbo kumakhala pang'onopang'ono, komwe kumapangitsa kuti magazi aziwongolera, komanso kumawonjezera kukhudzika kwa kusasangalala komanso kuchepa kwa chilimbikitso. Izi zokhala ndi mahospital GLP-1 ndi mankhwala atsopano a Victoza, omwe adapangidwa pamaziko ake, ndizofunikira kwambiri pakukonzekera moyo wa wodwala yemwe ali ndi matenda ashuga a 2.

Mankhwalawa amalonjeza kusintha kwa njira pothana ndi matendawa, omwe amadziwika padziko lonse lapansi ngati mliri. Odwala omwe ali ndi matenda a shuga a mtundu wachiwiri mpaka pano amakakamizidwa kumwa mapiritsi ambiri, omwe, kudzikundikira, adayamba kukhala ndi vuto pa impso.

Kupita patsogolo kwamatenda omwe amakakamizidwa kusintha ma jakisoni a insulin, omwe nthawi zambiri amakhala ndi khungu la hypoglycemia. Pakati pa odwala matenda ashuga, pali anthu ambiri onenepa kwambiri, chifukwa kuchuluka kwa shuga m'thupi kumakhudza mwachindunji kumverera kwa njala, ndipo ndizovuta kwambiri kupirira.

Mavuto onsewa adathetsedwa mothandizidwa ndi mankhwala atsopano a Victoza, omwe adatsimikiziridwa munthawi ya mayesero akulu azachipatala omwe adachitika nthawi imodzi komanso modziyimira pawokha mmaiko osiyanasiyana padziko lapansi, kuphatikiza ku Israel. Njira yabwino yosakira ma CD - mu mawonekedwe a cholembera - imalola jakisoni osakonzekereratu.

Wodwalayo, ataphunzira pang'ono, amatha kudzipatsira yekha mankhwalawo, osafunikira thandizo lakunja. Ndikofunikira kwambiri kuti Viktoza akuwonetsedwa kuti agwiritse ntchito kale magawo a shuga 2. Chifukwa chake, ndizotheka osati kungoyendetsa matendawa, komanso kuimitsa chitukuko chake, kupewa kuchulukana kwa zomwe munthu akudwala komanso kukula kwa zovuta za matenda ashuga.

Victoza: malangizo ogwiritsira ntchito

Mankhwala akuwonetsa odwala akulu omwe ali ndi matenda a shuga 2 omwe amakhala kumbuyo kwa zakudya ndi masewera olimbitsa thupi kukwaniritsa ulamuliro wa glycemic monga:

monotherapy, kuphatikiza mankhwalawa pogwiritsa ntchito mankhwala amodzi kapena angapo a hypoglycemic (omwe ali ndi metformin, sulfonylurea zotumphukira kapena thiazolidatediones) mwa odwala omwe sanakwaniritse zolondola za glycemic m'mbuyomu .

Zogwira ntchito, gulu: Liraglutide (Liraglutide), Hypoglycemic wothandizila - glucagon-ngati receptor polypeptide agonist

Fomu ya Mlingo: Njira yothetsera makonzedwe a sc

Contraindication

Hypersensitivity kwa yogwira mankhwala kapena zinthu zina zomwe zimapanga mankhwala, pakati, nthawi yoyamwitsa.

Mankhwala sayenera kugwiritsidwa ntchito kwa odwala omwe ali ndi matenda a shuga 1, omwe ali ndi matenda ashuga a ketoacidosis.

Iwo ali osavomerezeka kugwiritsa ntchito odwala:

ndi vuto lalikulu laimpso, ndi vuto la chiwindi, komanso kulephera kwa mtima kwa kalasi yothandizira ya IV-IV (malinga ndi gulu la NYHA), matenda otupa a m'matumbo, okhala ndi m'mimba mwa ana ndi achinyamata osakwana zaka 18.

Mlingo ndi makonzedwe

Victoza imagwiritsidwa ntchito 1 nthawi / tsiku nthawi iliyonse, mosasamala kanthu za kudya, imatha kuperekedwa ngati jakisoni wa sc pamimba, ntchafu kapena phewa. Malo ndi nthawi ya jakisoni zimatha kusiyanasiyana popanda kusintha kwa mlingo. Komabe, ndikofunikira kuperekera mankhwalawa nthawi yomweyo, nthawi yabwino kwa wodwala. Mankhwalawa sangathe kugwiritsidwa ntchito pakukonzekera ma iv ndi / m.

Mlingo

Mlingo woyambirira wa mankhwalawa ndi 0.6 mg / tsiku. Mukatha kugwiritsa ntchito mankhwalawa kwa sabata limodzi, mlingo uyenera kuchuluka mpaka 1.2 mg. Pali umboni kuti mwa odwala ena, kugwiritsa ntchito mankhwalawa kumawonjezeka ndi kuwonjezereka kwa mankhwalawa kuchokera ku 1.2 mg mpaka 1.8 mg.

Kuti akwaniritse kuwongolera bwino kwambiri kwa glycemic mwa wodwala ndikulingalira mphamvu ya chipatala, mlingo wa mankhwalawa ukhoza kuwonjezeka mpaka 1.8 mg mukamagwiritsa ntchito mlingo wa 1.2 mg kwa sabata limodzi. Kugwiritsa ntchito mankhwalawa tsiku ndi tsiku pamwambapa 1.8 mg ndikulimbikitsidwa.

Mankhwala tikulimbikitsidwa kuti azigwiritsidwa ntchito kuwonjezera pa mankhwala omwe alipo ndi Metformin kapena mankhwala ophatikizika ndi metformin ndi thiazolidinedione. Chithandizo cha metformin ndi thiazolidinedione chitha kupitilizidwa pa Mlingo wakale.

Zotsatira za pharmacological

Liraglutide ndi analogue ya glucagon yofanana ndi peptide-1 (GLP-1), yopangidwa ndi recombinant DNA biotechnology pogwiritsa ntchito Saccharomyces cerevisiae strain, yomwe ili ndi 97% ya Homology ya anthu ndi GLP-1, yomwe imamanga ndikuyambitsa zolandirira za GLP-1 mwa anthu.

Mbiri yayitali ya liraglutide pakubaya kwapansipansi imaperekedwa ndi njira zitatu: kudziphatikiza, komwe kumapangitsa kuti mankhwalawa achedwe, kumangiriza ku albumin komanso kuchuluka kwakukulu kwa enzymatic pokhudzana ndi dipeptidyl peptidase-4 (DPP-4) ndi ndale endopeptidase enzyme (NEP) , chifukwa chomwe T1 / 2 yayitali ya mankhwalawa amapezeka m'madzi a m'magazi.

Malangizo apadera

1. Njira zopewera kusamala ziyenera kuonedwa kuti zisayambitse kukula kwa hypoglycemia mukamayendetsa komanso kugwiritsa ntchito njira, makamaka pogwiritsa ntchito Viktoza kuphatikiza ndi zotumphukira za sulfonylurea.
2. Kugwiritsa ntchito mankhwalawa kuphatikizidwa kwa odwala omwe ali ndi matenda a shuga 1 kapena mankhwalawa a matenda ashuga a ketoacidosis.
3. Wowonongera sichilowa m'malo mwa insulin.
4. Kukhazikitsa liraglutide mwa odwala omwe akulandira kale insulin sikunaphunzire.

Ndemanga za Victoza

Sergey: Anandipeza ndi matenda a endocrinological omwe amalumikizidwa ndi vuto la chithokomiro. Adotolo adati choyamba muyenera kuchepetsa thupi, ndipo jekeseni wa Viktoza adayikidwa m'mimba. Mankhwalawa amamuunjikira cholembera, cholembera chimodzi chimakhala pafupifupi mwezi ndi theka. Mankhwalawa amalowetsedwa m'mimba.

M'masiku oyambilira jakisoni anali kudwala kwambiri ndipo samatha kudya kalikonse. Mwezi woyamba zidatenga ma kilogalamu 15, ndipo wachiwiri winanso 7. Mankhwalawa ndi othandizadi, koma chithandizo chitha ndalama zambiri. Thupi litazolowera, mavuto sanawonekere. Ndikwabwino kutenga singano zazifupi za jakisoni, chifukwa zilonda zimakhalabe zazitali.

Irina: Mankhwalawa ndi okwera mtengo kwambiri, ndipo mkatikati mwake muli ma syringe atatu okha. Koma ali omasuka mosaganizira - mutha kudzipangira nokha jakisoni, kulikonse. Ndidagwira jakisoni m'chafu, singano ya syringe ndi yapamwamba kwambiri, yopyapyala, padalibe kupweteka. Mankhwalawo pawokha, akaperekedwa, samapatsanso ululu, ndipo koposa zonse, Victoza ali ndi chidwi chodabwitsa.

Shuga wanga, yemwe ngakhale akugwiritsa ntchito mankhwala atatu sanatsike ndi 9,7 mmol, tsiku loyamba la chithandizo ndi Viktoza adatsikira ku mamilimita 5.1 osakonzeka ndipo adakhalabe tsiku lathunthu. Panali zovuta panthawi yomweyo, ndinali kudwala tsiku lonse, koma patatha masiku angapo nditagwiritsa ntchito mankhwalawa zidatha.

Elena: Ndikudziwa kuti mankhwalawa ndiwotchuka kunja. Anthu omwe ali ndi matenda ashuga akuigula ndi bang, chifukwa opanga sachita manyazi ndi kuchuluka. Amawononga ma ruble 9500. kwa syringe imodzi yomwe imakhala ndi 18 mg ya liraglutide. Ndipo izi ndizabwino kwambiri, m'misika ina 11,000 amagulitsidwa.

Zomwe ndizomvetsa chisoni kwambiri - sindinasinthe Viktoza. Mulingo wa shuga wamagazi sunatsike ndipo kulemera kwake kunakhalabe pamiyeso yomweyo. Sindikufuna kutsutsa omwe amapanga mankhwala chifukwa chosakwanira bwino pazinthu zawo, pali ndemanga zambiri zabwino za izo, koma ndili nazo monga choncho. Sizinathandize. Zotsatira zoyipa zimaphatikizapo nseru.

Tatyana: "Victoza" adandipatsa kuchipatala koyamba. Kufufuzako zingapo kunapangidwanso kumeneko, kuphatikizapo matenda osokoneza bongo, ziphuphu zakumaso, kunenepa kwambiri, komanso kuperewera kwa ubongo. "Victoza" adaperekedwa kuyambira masiku oyamba, jakisoni amapangidwa m'mimba. Poyamba, mavuto ambiri adawonetsedwa: chizungulire, mseru, kusanza. Patatha mwezi umodzi, kusanza kunatha.

Komabe, ndikuyambitsa kwake, muyenera kusiya kudya mafuta, kuchokera pachakudya choterocho, thanzi lanu limayamba kuipiraipira. Mlingo pang'onopang'ono umachulukirachulukira, monga momwe izi zimachitikira. Kwa miyezi ingapo ndinataya kilogalamu 30, koma nditangosiya jakisoni, ma kilogalamu angapo adabweranso. Mtengo wa zonse zogulitsa ndi singano zake ndi zazikulu, 10 zikwi za zolembera ziwiri, ma syringe a chikwi chimodzi pazingwe zana.

Igor: Ndili ndi matenda a shuga a 2, ndakhala ndikugwiritsa ntchito Victoza kwa nthawi yoposa chaka tsopano. Shuga adachokera 12, mankhwala atangotsika mpaka 7.1 ndikukhala pafupifupi ziwerengerozi, sizikwera kwambiri. Kulemera m'miyezi inayi kunapita 20 kilogalamu, sikumakweranso. Zimamveka zopepuka, chakudya chimakhazikitsidwa, ndizosavuta kumamatira ku chakudya.Mankhwalawa sanayambitse zovuta zilizonse, panali kukhumudwa pang'ono, koma kunadutsa mwachangu.

Konstantin: Ndili ndi matenda a shuga a 2, omwe amawoneka mwa ine pambuyo pa 40 chifukwa cha kunenepa kwambiri komanso kunenepa kwambiri. Pakadali pano, ndiyenera kutsatira kadyedwe kokhazikika komanso kuchita masewera olimbitsa thupi kuti ndichepetse kunenepa.

Mankhwalawa ndi osavuta chifukwa amatha kuperekedwa kamodzi patsiku popanda kumangirizidwa ndi zakudya. Victoza ali ndi cholembera chosavuta kwambiri, chosavuta kuyambitsa. Mankhwala sioyipa, amandithandiza.

Valentine: Ndinayamba kugwiritsa ntchito Viktoza miyezi iwiri yapitayo. Shuga adakhazikika, samadumphadumpha, pakhala kupweteka m'matumba, kuphatikizanso kwatayika kuposa ma kilogalamu 20, zomwe ndi zabwino kwambiri kwa ine. Mu sabata yoyamba kumwa mankhwalawa, ndinamva kunyansidwa - ndinali chizungulire, osachedwa (makamaka m'mawa). Endocrinologist adasankha Viktoza kuti akanthe m'mimba.

Jakisoni yekhayo alibe ululu, ngati mutasankha singano yoyenera. Ndinayamba kumwa Victoza ndi mlingo wochepa wa 0,6 mg, ndiye patatha sabata limodzi adotolo amawonjezeka mpaka 1.2 mg. Mtengo wa mankhwalawa, kuti muuike modekha, umafuna kukhala wabwino kwambiri, koma mikhalidwe yanga ndiyenera kusankha.

Liraglutide zochizira kunenepa kwambiri ndi matenda a shuga

Kunenepa kwambiri ndi vuto lalikulu la mahomoni. Pakadali pano pali mankhwala ambiri, kuphatikizapo liraglutide wochizira kunenepa kwambiri, womwe umapangidwanso pochiza odwala matenda a shuga.

Koma, zinthu zoyamba. Awa ndi matenda osachiritsika omwe amayamba chifukwa cha mphamvu osati chilengedwe, komanso za chibadwa, malingaliro, thupi komanso chikhalidwe cha anthu.

Momwe mungalimbane ndi kunenepa kwambiri

Pali zokambirana zambiri zonena za kunenepa kwambiri, seminare ndi misonkhano yamisonkhano imachitika pamlingo wapadziko lonse wokhudza matenda ashuga, endocrinology, mankhwala ambiri, zowona ndi maphunziro amaperekedwa pazotsatira za matendawa, ndipo kungoti munthu aliyense wakhala ndi vuto lokongoletsa. Kuti muthandizire odwala anu kuchepetsa thupi ndikukhala ndi zotsatira zabwino, ndikofunikira kufunsa katswiri wazokhudza endocrinology ndi zakudya.

Kukumbukira zonse zomwe zili pamwambapa, choyambirira, ndikofunikira kudziwa bwino mbiri yamatendawa. Chofunikira kwambiri pothandizira kunenepa kwambiri ndikukhazikitsa cholinga choyambirira - chomwe chimafuna kuchepetsa thupi. Pokhapokha pokhapokha ngati chithandizo chofunikira chitha kufotokozedwa bwino. Ndiye kuti, atafotokoza zolinga zomveka kuti athe kuchepetsa thupi, dokotala amamulembera pulogalamu yam'tsogolo ndi wodwala.

Kunenepa kwambiri

Chimodzi mwazomwe amamwa mankhwalawa ndi chida cha Liraglutide (Liraglutide). Sichatsopano, idayamba kugwiritsidwa ntchito mu 2009. Ndi chida chomwe chimachepetsa shuga mumagazi a seramu ndipo amalowetsedwa m'thupi.

Kwenikweni, amalembera mtundu wachiwiri wa matenda ashuga kapena kuthandizira kunenepa kwambiri, kuti aletse kuphatikizira kwa chakudya (glucose) m'mimba. Pakadali pano, kupanga mankhwala okhala ndi dzina lina lodziwika bwino "Saxenda" (Saxenda) kukhazikitsidwa pamsika wamtunduwu kumadziwika ndi dzina lodziwika bwino lotchedwa "Viktoza". Zomwezi zomwe zimakhala ndi mayina osiyanasiyana ogulitsa zimagwiritsidwa ntchito pochiza odwala omwe ali ndi mbiri ya matenda ashuga.

Liraglutide anafuna zochizira kunenepa. Kunenepa kwambiri, wina anganene, "kuneneratu" kwa matenda ashuga wazaka zilizonse. Chifukwa chake, polimbana ndi kunenepa kwambiri, timapewa kuyambika ndi kukula kwa matenda ashuga.

Mfundo yogwira ntchito

Mankhwalawa ndi chinthu chopezeka mosiyanasiyana, chofanana ndi peptide ya glucagon. Mankhwalawa ali ndi mphamvu yayitali, ndipo kufanana kwake ndi 97% ndi peptide iyi. Ndiye kuti, akaphatikizidwa m'thupi, amayesa kumunyenga.

Popita nthawi, pamakhala kusintha kwa zinthu zachilengedwe zomwe zimayambitsa insulini. Izi zimabweretsa matenda a shuga. Kulowa m'magazi, liraglutide imawonjezera kuchuluka kwa matupi a peptide. Zotsatira zake, kapamba ndi ntchito yake zimakhalanso zabwinobwino.

Mwachilengedwe, shuga m'magazi amatsika msanga. Zakudya zomwe zimalowa m'thupi ndi chakudya zimayamba kuyamwa bwino, shuga m'magazi amakhala osakhazikika.

Mlingo ndi njira ntchito

Liraglutide amagwiritsidwa ntchito pochiza kunenepa kwambiri. Pofuna kukhazikitsidwa mosavuta, cholembera chimbira chomwe chimamalizidwa chimagwiritsidwa ntchito. Izi zimapangitsa kuti ikhale yosavuta komanso yosavuta kugwiritsa ntchito. Kuti mudziwe mlingo wofunikira, syringe imakhala ndi magawano. Gawo limodzi ndi 0,6 mg.

Kusintha kwa Mlingo

Yambani ndi 0,6 mg. Kenako imachulukitsidwa ndi kuchuluka komweko sabata iliyonse. Bweretsani kwa 3 mg ndikusiya mlingo mpaka maphunzirowo atha. Mankhwalawa amaperekedwa popanda malire a tsiku lililonse, chakudya chamasana kapena kugwiritsa ntchito mankhwala ena m'chafu, phewa kapena pamimba. Malowa a jakisoni amatha kusinthidwa, koma mlingo sasintha.

Yemwe amawonetsedwa ngati mankhwalawo

Chithandizo cha mankhwalawa chimangoperekedwa ndi dokotala (!) Ngati palibe kulemera kwazomwe anthu odwala matenda ashuga amachita, ndiye kuti mankhwalawa ndi mankhwala. Ikani momwemo ndipo ngati cholozera cha hypoglycemic chaphwanyidwa.

Contraindication kuti agwiritse ntchito:

Milandu yokhala osalolera payekha imatheka. Sitha kugwiritsidwa ntchito ngati matenda a shuga 1. Mitundu yambiri yaimpso ndi kwa chiwindi. 3 ndi 4 mtundu wa kulephera kwa mtima. Matumbo amkati ogwirizana ndi kutupa. Chithokomiro cha chithokomiro. Mimba

Ngati pali jakisoni wa insulin, ndiye kuti nthawi yomweyo mankhwala osavomerezeka. Ndikosayenera kugwiritsa ntchito muubwana komanso omwe adadutsa zaka 75 zaka. Mosamala kwambiri, ndikofunikira kugwiritsa ntchito mankhwalawa pamitundu yosiyanasiyana ya mtima.

Zotsatira zoyipa

Zambiri mwa zoyipa zoyipa zimawonekera ndi kugaya chakudya. Amatha kuwonetsedwa ngati akusanza, kutsegula m'mimba. Mwa ena, m'malo mwake, kukulitsa kudzimbidwa kumadziwika. Anthu omwe amamwa mankhwalawa amatha kukhala atatopa ndikumakhala kutopa ndi kutopa. Zotheka ndipo zochita atypical kuchokera mthupi monga:

mutu, bloating, tachycardia, kukula kwa thupi lawo siligwirizana.

Mphamvu ya kugwiritsa ntchito mankhwalawa

Kuchita kwa mankhwalawa kumadalira kuti kuyamwa kwa chakudya kuchokera m'mimba kumalepheretsa. Izi zimadzetsa kuchepa kwa chikhumbo, chomwe chimaphatikizapo kuchepa kwa kudya kwa pafupifupi 20%.
Mankhwalawa a kunenepa kwambiri amagwiritsidwa ntchito kukonzekera kwa Xenical (the yogwira mankhwala orlistat), Reduxine, kuchokera ku mankhwala atsopano a Goldline Plus (chinthu chogwiritsidwa ntchito ndi sibutramine kutengera mankhwalawa), komanso opaleshoni ya bariotric.