Glucophage kapena Glucophage Long: ndibwino bwanji?
Ndi matenda a shuga a mtundu wachiwiri, kagayidwe kakang'ono ka mafuta m'thupi kamasokonekera, komwe nthawi zambiri kumayambitsa kunenepa kwambiri. Kuti muchepetse kunenepa kwambiri, muyenera kumwa mankhwala ena apadera omwe amachepetsa shuga komanso kusintha mafuta kagayidwe. Zochita, pochiza matenda ashuga, madokotala nthawi zambiri amapereka Glucophage kapena Glucophage Long. Mankhwalawa ali ndi zotsatira zofanana zochizira, koma pali kusiyana pang'ono.
Koma pali kusiyana kotani pakati pa mankhwala? Kodi ma mankhwalawa ndi otani? Ndipo ndi iti mwa mankhwalawa omwe ali bwino? Pansipa tikambirana izi.
Khalidwe la Glucophage
Ndiwothandizira othandizira. Amachepetsa shuga ya magazi popanda kuchititsa hypoglycemia. Pa mankhwala ndi mankhwala, zotsatirazi zimachitika:
- khungu limazindikira kuchuluka kwa insulini, kuchuluka kwa shuga kumayamba,
- kuyamwa kwamatumbo kumachepetsa,
- Imachepetsa kupanga shuga m'magazi a chiwindi,
- kagayidwe ka mafuta kamakhala bwino, cholesterol level imachepa.
Mankhwalawa amagwira ntchito pamaso pa prediabetes komanso zinthu zomwe zingayambitse kukula kwa matendawa. Zimathandizira ngakhale zakudya komanso njira zina zosagwiritsa ntchito mankhwala zomwe zimakupatsani chithandizo sizikukulolani kuti mukwaniritse zomwe mukufuna.
Kuyerekezera kwa Glucophage, Kuyerekezera Kwakukulu kwa Glucophage
Kuti musankhe mankhwalawa amodzi mwa 2, muyenera kuphunzira mawonekedwe ofanana ndi mankhwala.
Zodziwika bwino zamankhwala ndi:
- Kupanga. The yogwira mankhwala a mankhwala ndi metformin - hypoglycemic wothandizira. Chithandizo chothandizira chomwe chimagwiritsidwa ntchito ndi mankhwalawa ndi magnesium stearate.
- Kutulutsa Fomu. Mankhwalawa amapezeka mu mawonekedwe a biconvex mapiritsi amtundu woyera. Glucophage imakhala ndi mawonekedwe ozungulira, ndipo mtundu wake wautali ndi capular.
- Zomwe zimakhudza thupi. Mankhwala amachepetsa shuga m'magazi, zimawonjezera chidwi cha maselo, minofu ndi ziwalo mpaka insulin.
- Zizindikiro zogwiritsidwa ntchito. Mankhwala amagwiritsidwa ntchito pochiza matenda ashuga amtundu wa 2 ngati kusintha kwamakhalidwe sikubweretse zotsatira zomwe mukufuna. Glucophage ingagwiritsidwe ntchito osati pazachipatala, komanso pofuna kupewa.
- Contraindication Wamba contraindication ndi tsankho, chiwindi kapena matenda a impso, matenda a shuga komanso chikomokere, matenda okhudzana ndi matenda amisempha, matenda a shuga (pakufunika insulin), njira yomwe ikubwera kapena yaposachedwa kafukufuku wa radioisotope kapena radiology yogwiritsa ntchito iodine yomwe ili ndi zosiyana pakati.
- Malonda ogulitsa. Mankhwala othandizira amapezeka kokha kuchokera ku malo ogulitsa mankhwala. Sizoletsedwa kuwatenga popanda chilolezo chodwala, chifukwa izi zimatha kuyambitsa zovuta.
- Zotsatira zoyipa. Mukamagwiritsa ntchito mankhwala, kusintha kosafunikira kumatha kuchitika mwa kuchepa kwa magazi, urticaria, lactic acidosis, kusokonezeka kwa dongosolo la chakudya (kusadya bwino, kutsegula m'mimba, kupangika kwa mpweya, nseru).
- Wopanga Mankhwalawa amapangidwa ku France ndi kampani yopanga mankhwala MERCK SANTE.
- Gwiritsani ntchito pa nthawi yoyembekezera. Mukanyamula ana, ndalama sizimagwiritsidwa ntchito, chifukwa zimatha kusokoneza kukula kwa mwana wosabadwayo.
Mankhwalawa pogwiritsa ntchito glucophage, chidwi cha maselo kuti insulin iwonjezeke, kuyamwa kwa glucose kumakhala bwino.
Kodi pali kusiyana kotani?
Kusiyana kwa mankhwalawa kuli motere:
- Mndandanda wazinthu zowonjezera. Zothandizira zothandizira za Glucophage ndi Povidone, ndi Glucophage Long - sodium carmellose, MCC, hypromellose. Magnesium stearate ilipo m'mankhwala onse awiri.
- Kuzungulira kwa yogwira gawo. Glucophage imakhala ndi 500, 850 kapena 1000 mg ya metformin, ndipo mtundu wautali uli ndi 500, 750 kapena 1000.
- Gwiritsani ntchito ana. Glucophage angagwiritsidwe ntchito kuyambira zaka 10. Kutalika kumapangidwa kuti mugwiritse ntchito unyamata, ubwana.
- Kutalika kwa chochita. Kuchuluka kwa metformin mukamagwiritsa ntchito Glucofage kumatheka pambuyo pa maola 2,5, komanso kugwiritsa ntchito analogue, pambuyo pa maola 7-12.
- Njira yogwiritsira ntchito. Mlingo woyamba wa Glucofage ndi 500 mg. Kenako imakwera mpaka 1500-2000 mg. Mlingo wa tsiku ndi tsiku umagawidwa mu ma servings a 2-3, omwe amachepetsa chiopsezo cha mavuto. Glucophage Long imatengedwa usiku, nthawi yamadzulo. Mlingo umatengera momwe thupi limakhalira ndi mawonekedwe ake, zaka, mawonekedwe a matendawa komanso kuuma kwake. Imwani mapiritsi 1 kamodzi patsiku.
Kuchepetsa thupi
Mukunenepa kwambiri, mumatha kumwa onse awiriwa. Glucophage ndi yoyenera poletsa kukula kwa matenda ashuga, ndipo Kutalika ndikoyenera pochiza matenda omwe alipo.
Mukunenepa kwambiri, pochiza matenda omwe alipo, Glucophage Long.
Ndemanga za Odwala
Irina, wazaka 40, Kostroma: “Makolo anga anali ndi matenda a shuga, ndipo nthawi zonse ndimawopa matenda. Mapaundi owonjezera atayamba kuwonekera, ndidatembenukira kwa endocrinologist. Dotoloyo adati kunenepa kwambiri kumatha kuyambitsa matenda ashuga, ndikuwonetsa Glucofage. Mankhwalawa atangoyamba kumene, zotsatira zoyipa (nseru ndi matenda otsekula m'mimba) zinaonekera, koma patatha sabata limodzi zonse zidapita. Ndinalembetsa ku masewera olimbitsa thupi, ndinayamba kudya zakudya zoyenera. Kuchepetsa thupi pang'onopang'ono. ”
Mikhail, wazaka 45, ku St. Petersburg: “Ndimadwala matenda ashuga. Chithandizo chokhacho chomwe chimakulolani kuti musunge shuga mkati mwa nthawi yokhazikika ndi Glucofage Long. Ndimamwa kamodzi patsiku chakudya chamadzulo, chomwe ndichabwino. Amamva bwino, kunenepa kwambiri kwatha. ”
Madokotala amawunika Glucophage ndi Glucophage Kutalika
Anastasia Valerievna, woyang'anira endocrinologist, ku Moscow: “Ngati wodwalayo ali ndi lingaliro lakakulitsa matenda ashuga, kuyang'anira shuga wamagazi pafupipafupi nkofunika. Popewa matendawa, Glucofage angagwiritsidwe ntchito. Zatsimikizira kufunikira kwachipatala ndipo ndi zotsika mtengo. Kunenepa kwambiri amathanso kugwiritsidwa ntchito. ”
Sergey Anatolyevich, endocrinologist, Tula: “Mankhwala osokoneza bongo amathandizira kunenepa kwambiri komanso matenda ashuga. Musanagwiritse ntchito, muyenera kuwerengera mosamala malangizo, kuphatikizapo gawo lokhudzana ndi mankhwala. Kusamala kumafunika kugwiritsa ntchito nthawi yomweyo ya Nifedipine, okodzetsa, mankhwala a cationic omwe amapezeka mu aimpso tubules, ndi mankhwala ena.
Glucophage: Golide wa Chithandizo
Glucophage imayikiridwa ndi Merck Sante ndipo imapangidwa m'malo opanga ku France. Mapiritsi okhala ndi Mlingo wa 500 mg ndi 850 mg - kuzungulira, ndi mulingo wa 1000 mg - chowulungika, wokhala ndi notch «1000». Zomwe zimagwira metformin, mankhwala opangidwa kuchokera ku gulu la Biguanides. Mlingo woyambira umayamba ndi 500-850 mg katatu patsiku, pafupifupi tsiku lililonse 3000 mg. Glucophage kwa zaka makumi angapo motsatizana akhalabe pamalo ake oyamba a mankhwala antidiabetic.
Glucophage Long: Palibe malire pa ungwiro
Mankhwala oyambilira amapezekanso ku France, koma adapangidwa pambuyo pake ndi Glucofage. “Kutalika” kumatanthauza kumasulidwa kwa mankhwalawo. Mapiritsi oyera, ozungulira, mlingo wa 500 mg ndi 750 mg wolemba "500" kapena "750".
Piritsi ili ndi zigawo ziwiri: gawo lakunja ndi chipolopolo choteteza chomwe chili ndi katundu wapadera, mkati mwake muli metformin. Ikamezedwa, piritsi limalowa m'mimba, gawo lake lakunja limayamba kuyamwa madzi ndikutupa, ndikusintha kukhala gel. Metformin imachoka pogona pang'onopang'ono, imadutsa mu gel, ndikulowera m'magazi. Glucophage Long imachedwa m'mimba, imapatsa thanzi mankhwalawa.
Mlingo woyambira - 500 mg kamodzi patsiku, tsiku lililonse - 2000 mg.
Kodi akulu ndi abale achinyamata amafanana chiyani?
Glucose Eater (zomwe Glucophage amamasulira kuchokera ku Chingerezi) amakwaniritsa cholinga chake m'njira zingapo:
- Imachepetsa mayamwidwe am'madzi mu chakudya m'matumbo a lumen.
- Chimalimbikitsa kusamutsa moyenera mamolekyulu a glucose kuchokera m'magazi kupita ku cell.
- Imachepetsa kapena kutsekereza kupangika kwa glucose ndi hepatocytes - maselo a chiwindi.
- Imabwezeretsa kulumikizika kotayika pakati pa insulin ndi mapuloteni apadera pamaselo a cell omwe amalola insulin kudutsa.
- Imathandizira kaphatikizidwe wa lactate kuchokera ku glucose, potero amawasokoneza mu matumbo a lumen.
Mankhwala onsewa akuwonetsedwa:
- Odwala omwe ali ndi matenda amtundu wa 2, kuphatikiza achinyamata.
- Odwala onenepa kwambiri.
- Odwala omwe ali ndi matenda ashuga asanachitike, kuphatikizapo insulin.
Kuphatikiza kosayembekezereka koma kosangalatsa ndikuthekera kwa metformin kuwongolera kuchuluka kwa mafuta oyipa, kuteteza mitsempha yamagazi ndi mtima.
Kodi pali kusiyana kulikonse?
Malamulo a moyo wa matenda ashuga a 2 akusintha. Kuphatikiza pa kusintha zakudya zomwe zizolowetsedwa, kuphatikizidwa pakulamulira kwake kochita masewera olimbitsa thupi, wodwalayo akukumana ndi kufunika kwa mankhwala okhazikika. Kodi munthu angagwiritse ntchito zimadalira njira iyi: chosavuta kumwa piritsi limodzi patsiku kapena angapo, kumwa iwo mutatha kadzutsa, nkhomaliro ndi chakudya chamadzulo, kapena usiku wokha?
Glucophage Long imapereka mwayi wosatsutsika. Njira yodabwitsa ya piritsi imakuthandizani kuti muzimwa kamodzi kokha patsiku, madzulo mukatha kudya. Simufunikiranso kukumbukira ngati Mlingo unakusowa masana kapena ayi.
Kuchepetsa pafupipafupi kwa makonzedwe kumachepetsa chiopsezo chotsatira zoyipa, makamaka kuchokera m'mimba ndi matumbo.
Glucophage pamene ilowa m'thupi limagawanika mwachangu, gawo latsopano limafunikira kuti lizikhala ndende pantchito. Chifukwa chake, kumwa piritsi limodzi kumakhala kosakwanira, mankhwalawa amapatsidwa katatu patsiku.
Ndiye ndi mankhwala ati?
Chisankho chimatengera kutalika kwa matenda, kuchuluka kwa kuzindikira ndi moyo. Odwala omwe amakonda kulumpha zakudya ayenera kusankha Glucofage Long. Kwa anthu achikulire, kudandaula kuti akusokoneza, kuyiwalanso, ndikofunikira kupangira mankhwala ndikamasulidwa nthawi yayitali.
Glucophage imalembedwa kwa odwala pamene kuchuluka kwathunthu kwa tsiku kumapitirira 2 magalamu.
Wodwala akangoyamba kukaonana ndi adotolo, omwe adapezeka ndi matenda ashuga, chithandizo chimayambiranso ndi Glucofage. Mankhwalawa amathandizidwa masana masana ndikuwona kuchuluka kwa zomwe wodwala amapeza. Kuwonjezeka kwapang'onopang'ono kwa mlingo kumapangitsa kutsata zovuta zomwe zikubwera ndikuzilepheretsa panthawi yake. Ngati wodwala amatenga mankhwala ena ambiri, ndiye kuti chithandizo cha matenda ashuga chimayamba ndi Glucofage kuti mupeze kuyanjana ndi mankhwala ena. Mukatsimikizira kuti zonse zili m'dongosolo, pitani ku Glyukofazh Long.
Upangiri wokhazikitsa mankhwala kapena mankhwala ena omwe ndi a dokotala wokhawo, ndi kwa iye kusankha zomwe zili zabwino kwa wodwalayo.
Kodi glucophage imagwira ntchito bwanji?
Mankhwalawa ndi mankhwala a hypoglycemic. Amachepetsa kuchuluka kwa shuga m'magazi, ogwiritsidwa ntchito pochiza matenda ashuga. Mapiritsiwo amakhala oyera, ozungulira komanso ozungulira.
Glucophage ndi Glucophage Long amatengedwa kuti ndi biguanides, i.e. shuga wamagazi.
Chofunikira chachikulu pakupanga glucophage ndi metformin. Pawiri iyi ndi Biguanide. Ali ndi vuto la hypoglycemic chifukwa chakuti:
- chiwopsezo cha maselo a cell kuti insulin iwonjezeke, shuga amayamba kugwira,
- kukula kwa shuga m'magulu a chiwindi amachepa,
- pakuchedwa kuchepa kwam'mimba ndi matumbo,
- kagayidwe kachakudya mafuta mafuta bwino, cholesterol ndende kumachepa.
Metformin siyimakhudzanso kuchuluka kwa insulin kapangidwe ka ma cell a kapamba, mankhwalawa sangapangitse hypoglycemia.
Mukatha kugwiritsa ntchito mankhwalawa, gawo logwira limadutsa m'matumbo kulowa m'magazi ambiri. Bioavailability ndi pafupifupi 60%, koma ngati mumadya, ndiye kuti chizindikiro chake chimachepa. Kuchuluka kwa metformin m'magazi kumawonedwa pambuyo maola 2,5. Poda imeneyi imakonzedwa pang'ono m'chiwindi ndikupukusidwa ndi impso. Theka lonse la mankhwalawa limachoka mu maola 6-7.
Kuyerekeza mitundu ya mita ya Accu-Chek - zambiri munkhaniyi.
Khalidwe Glucophage Kutalika
Ndi othandizira a hypoglycemic ochokera pagulu la Biguanide. Mankhwalawa amapezeka mu mawonekedwe a mapiritsi okhala ndi nthawi yayitali. Chidacho chimapangidwanso kuti muchepetse shuga. Gawo lomwe limagwiritsa ntchito mankhwalawo lilinso metformin.
Chidacho chimachita chimodzimodzi ndi Glucofage: sichikukulitsa kupanga insulin, sichitha kupangitsa hypoglycemia.
Mukamagwiritsa ntchito Glucofage Long, mayamwidwe a metformin amayamba pang'onopang'ono kuposa mapiritsi omwe ali ndi kanthu. Kuchuluka kwazomwe yogwira ntchito m'magazi kudzawonetsedwa pambuyo pa maola 7, koma ngati kuchuluka kwa zinthu zomwe zatengedwa ndi 1500 mg, ndiye kuti nthawi ya nthawi ifika maola 12.
Mukamagwiritsa ntchito Glucofage Long, mayamwidwe a metformin amayamba pang'onopang'ono kuposa mapiritsi omwe ali ndi kanthu.
Kodi Glucophage ndi Glucophage Kutalika ndi chinthu chomwecho?
Glucophage ndi mankhwala othandiza a hyperglycemia. Chifukwa cha kagayidwe kachakudya kosavuta, mafuta oyipa sadzikundikira. Mankhwalawa samakhudza kukula kwa kupanga kwa insulin, chifukwa chake amadziwikiridwa ngakhale kwa anthu omwe alibe shuga.
Wothandizira wina wa hypoglycemic ndi Glucophage Long. Izi ndi zofanana ndi zam'mbuyomu. Mankhwalawa ali ndi zofanana, zokhazo zochizira ndizokhazikika. Chifukwa cha kuchuluka kwakukulu kwa gawo lomwe limagwira, limatengedwa nthawi yayitali mthupi, ndipo mphamvu zake zimakhala zazitali.
- kuthandiza pa matenda a shuga
- khazikitsani kuchuluka kwa shuga ndi insulin,
- phindu pa kagayidwe ndi kugwiritsa ntchito chakudya chamagulu,
- kupewa matenda a mtima, kuchepetsa cholesterol.
Mankhwala onsewa amaloledwa kumwa pokhapokha atauzidwa ndi dokotala kuti apewe kukula kwa zovuta mthupi.
Kuyerekeza Glucophage ndi Glucophage wa Kutalika
Ngakhale kuti mankhwalawa amagwiritsidwa ntchito ngati mankhwala omwewo, ali ndi kufanana komanso kusiyana.
Zogulitsa zonsezi zimapangidwa ndi MERCK SANTE kuchokera ku France. M'mafakitala, samaperekedwa popanda kulandira mankhwala. Zotsatira zakuchiritsika za mankhwalawa ndizofanana, chinthu chachikulu mu zonse ndi metformin. Fomu ya Mlingo - mapiritsi.
Mankhwala onsewa amaloledwa kumwa pokhapokha atauzidwa ndi dokotala kuti apewe kukula kwa zovuta mthupi.
Kugwiritsa ntchito mankhwalawa kumabweretsa kuponderezedwa kwa zomwe zimachitika ndi vuto la hyperglycemic. Kuchita modekha kumakupatsani mwayi wothandizira matenda, zizindikiro za shuga, ndikuchita izi munthawi yake.
Zizindikiro zazikulu zogwiritsidwa ntchito m'mankhwala ndizofanana. Mankhwalawa amagwiritsidwa ntchito pazotsatirazi:
- lembani matenda ashuga 2, pomwe chithandizo cha zakudya sichithandiza,
- kunenepa.
Mankhwala amapatsidwa mankhwala osokoneza bongo kwa ana opitirira zaka 10. Kwa mwana wocheperapo ndi zaka zino (kuphatikiza akhanda), mankhwalawa sioyenera.
Contraindication pakugwiritsa ntchito mankhwala ndi omwewo:
- chikomokere
- matenda ashuga ketofacidosis,
- kuwonongeka kwaimpso,
- mavuto a ntchito kwa chiwindi,
- kuchuluka kwa matenda osiyanasiyana,
- malungo
- matenda oyambitsidwa ndi matenda
- kusowa kwamadzi
- kukonza pambuyo kuvulala,
- kukonzanso pambuyo pa ntchito,
- kuledzera
- Zizindikiro za lactic acidosis,
- mimba ndi mkaka wa m`mawere
- Hypersensitivity pamagawo a mankhwala.
Nthawi zina mankhwala amayambitsa mavuto:
- kugaya chakudya cham'mimba thirakiti: nseru, kuchepa kwa chakudya, kutsegula m'mimba, kugona mwachangu,
- lactic acidosis
- kuchepa magazi
- urticaria.
Ndi mankhwala osokoneza bongo a Glucophage kapena Glucophage Long, zizindikiro zotsatirazi zimawonekera:
- kutsegula m'mimba
- kusanza
- malungo
- kupweteka m'mimba mwa m'mimba
- kupuma kwamphamvu
- mavuto ndi mgwirizano wamagulu.
Munthawi zonsezi, muyenera kusiya kumwa mankhwalawo ndikuyimbira ambulansi. Kuyeretsa kumachitika ndi hemodialysis.
Zomwe zili bwino - Glucofage kapena Glucofage Long?
Mankhwalawa amathandizira mtima wamagazi, amathandizira kulimbana ndi mapaundi owonjezera, kukonza bwino thanzi ndikupangitsa matenda a shuga m'magazi kukhala ndi shuga. Koma, chomwe chiri bwino kwa wodwalayo, ndi dokotala yekhayo amene amawona, kutengera matendawa, mawonekedwe ake, kuwuma, mkhalidwe wa wodwalayo, kupezeka kwa ma contraindication.
Mankhwala onse awiriwa ali ndi magawo omwe amagwira ntchito, opindulitsa katundu, zoyipa, zotsutsana.
Mitundu ya kumasulidwa kwa mankhwala, kapangidwe kake ndi ma CD
Mapangidwe onsewa ali ndi metformin hydrochloride monga chinthu chachikulu chogwira ntchito. Mapiritsi a Glucofage amakhala ndi povidone ndi magnesium stearate ngati zida zothandizira.
Glucofage film membrane imakhala ndi hypromellose.
Kapangidwe ka mapiritsi a Glucophage Long amasiyana ndi Glucophage mwa kukhalapo kwa zida zina zothandizira.
Kukonzekera kumasulidwa kumakhala ndi zotsatirazi ngati zina zowonjezera:
- Carlone sodium.
- Hypromellose 2910.
- Hypromellose 2208.
- Microcrystalline mapadi.
- Magnesium wakuba.
Mapiritsi a mankhwalawa ndi nthawi yake yoyeretsedwa amakhala oyera pamtundu ndipo amakhala ndi mawonekedwe a biconvex.
Mankhwala omwe akhala akuchita kwa nthawi yayitali ali ndi khungu loyera, ndipo mapiritsi ake ndi kapu ndi biconvex. Piritsi lililonse kumbali imodzi linajambulidwa ndi nambala 500.
Mapiritsi a mankhwalawa amadzaza matuza a 10, 15 kapena 20 zidutswa. Matumba amayikidwa m'makatoni oikidwa, omwe amakhalanso ndi malangizo ogwiritsira ntchito.
Mitundu yonse iwiri yamankhwala imagulitsidwa kokha mwalemba.
Mankhwala amayenera kusungidwa m'malo osavomerezeka ndi ana. Kutentha sikuyenera kupitirira 25 digiri Celsius. Alumali moyo wa mankhwala ndi zaka 3.
Tsiku lotha ntchito kapena kuphwanya malamulo osungidwa ndi wopanga, kugwiritsa ntchito mankhwala ndikoletsedwa. Mankhwala oterowo ayenera kutayidwa.
Zochita zamankhwala
Kutenga Glucophage ndi Glucophage Kutalika kwa mankhwalawa kumathandizira kuimitsa kaye zizindikiritso zokhudzana ndi kukula kwa chikhalidwe cha hyperglycemic m'thupi.
Kusintha kofatsa kwamthupi kumapangitsa kuwongolera njira yamatendawa ndikuwongolera zomwe zili ndi shuga mthupi.
Kuphatikiza pa chinthu chachikulu, mankhwalawa ali ndi zabwino zingapo, zazikulu zomwe ndizothandiza thupi komanso mwayi wogwiritsa ntchito mankhwalawa kuti mupewe kukula kwa zovuta zogwirizana ndi ntchito ya mtima, mtima ndi impso.
Zizindikiro zazikulu pakugwiritsa ntchito Glucophage ndi Glucophage Long ndizofanana.
Mankhwala amagwiritsidwa ntchito ngati wodwala ali:
- shuga osadalira insulini, chifukwa chogwiritsa ntchito mankhwala othandizira odwala
- kunenepa
- kukhalapo kwa mtundu wachiwiri wa shuga kwa achinyamata omwe ali ndi odwala osaposa zaka 10.
Contraindication pakumwa mankhwala ali motere:
- Kukhalapo kwa zizindikiro za chikomokere.
- Zizindikiro zakukula kwa matenda ashuga ketoacidosis.
- Kusokonekera mu ntchito ya impso.
- Kupezeka mu thupi la matenda pachimake, omwe amayenda limodzi ndi mawonekedwe a zosokoneza mu impso, wodwalayo ali ndi vuto, kukula kwa matenda opatsirana, kuchepa magazi ndi kukula kwa hypoxia.
- Kuchita njira zopangira opaleshoni ndikuvulaza kwambiri odwala.
- Kuphwanya maliseche ndi chiwindi.
- Kupezeka kwa poyizoni mowa poyipa wodwala komanso uchidakwa.
- Wodwala ali ndi zizindikiritso za mkaka acidosis.
- Nthawi ndi maola 48 asanafike ndipo 48 atapenda thupi atagwiritsa ntchito njira za x-ray momwe amagwiritsa ntchito ayodini.
- Nthawi yobereka mwana.
- Kukhalapo kwa hypersensitivity ku zigawo za mankhwala.
- Nthawi yochepetsetsa.
Sitikulimbikitsidwa kugwiritsa ntchito mankhwalawa ngati wodwalayo ali ndi zaka zopitilira 60, komanso odwala omwe awonjezera zolimbitsa thupi.
Izi ndichifukwa chakuwonjezeka kwa zizindikiro za lactic acidosis mthupi.
Malangizo ogwiritsira ntchito mapiritsi
Mankhwala amaperekedwa pakamwa.
Mankhwalawa amagwiritsidwa ntchito kuphatikiza ndi monotherapy ya mtundu 2 matenda a shuga.
Nthawi zambiri, dokotala yemwe amapezekapo amayamba kupatsidwa mankhwala mosiyanasiyana ndi 500 kapena 850 mg katatu patsiku. Mankhwalawa amayenera kumwedwa mutangotha kudya kapena pakudya.
Ngati ndi kotheka, kuwonjezereka kwa mlingo wa mankhwalawa ndikotheka. Lingaliro lakuwonjezera Mlingo wogwiritsidwa ntchito pochiza matenda a shuga 2 amapangidwa ndi adotolo, potengera momwe wodwalayo akuwonera ndi zomwe adapeza pakuwunika thupi.
Pogwiritsa ntchito mankhwalawa ngati mankhwala othandizira, Mlingo wa Glucofage umatha kufika 1500-2000 mg patsiku.
Kuti muchepetse kuthana ndi mavuto, muyeso wa tsiku ndi tsiku umagawidwa mu Mlingo wa 2-3 patsiku. Mlingo woyenera wovomerezeka wa mankhwalawa amatha kufikira 3000 mg patsiku. Mlingo wa tsiku ndi tsiku woterewu umayenera kugawidwa m'magawo atatu, omwe amalumikizidwa ndi zakudya zazikulu.
Kuwonjezeka kwapang'onopang'ono kwa Mlingo wogwiritsidwa ntchito kungachepetse kuyipa kwa mavuto obwera chifukwa cha kumwa mankhwalawa m'mimba.
Ngati wodwala atenga Metformin 500 pa mlingo wa 2000-3000 mg tsiku lililonse, amatha kusamutsidwa ndi Glucofage pa mlingo wa 1000 mg patsiku.
Kumwa mankhwalawa kumatha kuphatikizidwa pogwiritsa ntchito othandizira ena a hypoglycemic.
Kugwiritsidwa ntchito munthawi ya matenda a shuga a mtundu wachiwiri, mankhwala a nthawi yayitali, makonzedwe amachitika kamodzi patsiku. Ndikulimbikitsidwa kutenga Glucofage Long nthawi yamadzulo chakudya.
Kugwiritsa ntchito mankhwalawa kuyenera kutsukidwa ndi madzi okwanira.
Mlingo wa mankhwala Glucofage omwe amagwiritsidwa ntchito nthawi yayitali amasankhidwa ndi dokotala payekhapayekha, poganizira zotsatira za mayeso ndi machitidwe a thupi la wodwalayo.
Ngati nthawi yakumwa mankhwalawo yakusowa, mankhwalawa sayenera kuchuluka, ndipo mankhwalawo amayenera kumwedwa molingana ndi dongosolo lomwe adotolo adalandira.
Ngati wodwala samapereka chithandizo ndi Metformin, ndiye kuti mlingo woyambirira wa mankhwalawa ukhale 500 mg kamodzi patsiku.
Amaloledwa kuwonjezera Mlingo womwe umangotenga masiku khumi ndi anayi pambuyo pa kuyezetsa magazi kwa glucose.
Zotsatira zoyipa mukamamwa mankhwala
Zotsatira zoyipa zomwe zimadza pakumwa mankhwala zimatha kugawidwa m'magulu angapo, kutengera kupezeka kwa thupi.
Nthawi zambiri, zotsatira zoyipa za m'mimba, zamanjenje, ma hepatobiliary system zimawonedwa.
Kuphatikiza apo, zotsatira zoyipa zimatha kukhala pakhungu ndi metabolic.
Kuchokera kumbali yamanjenje, kusokonezeka kwa ntchito kwa masamba kumakonda kumawonedwa, kutsekemera kwazitsulo kumawonekera pamlomo wamkamwa.
Kuchokera pamimba yogaya, mawonekedwe a zovuta monga:
- kumva mseru
- kufuna kusanza
- kukula kwa matenda otsegula m'mimba,
- Maonekedwe a ululu m'mimba,
- kusowa kwa chakudya.
Nthawi zambiri, zoyipa zam'mimba zimayambira koyambirira kwa mankhwala ndikugwiritsa ntchito mankhwalawa kuzimiririka. Pofuna kuchepetsa kuthekera kwa mavuto, mankhwalawa amayenera kumwedwa nthawi yomweyo ndi chakudya kapena mukangodya.
Kumbali ya dongosolo la hepatobiliary, zotsatira zoyipa zimawoneka kawirikawiri kwambiri ndipo zimawoneka m'mavuto pakuchitika kwa chiwindi. Zotsatira zoyipa za mankhwalawa zimatha atasiya kugwiritsa ntchito mankhwalawa.
Osowa kwambiri, panthawi ya chithandizo, matupi awo sagwirizana ndi pakhungu amayamba kuwoneka ndi kuyambitsa urticaria.
Kugwiritsa ntchito Glucofage kumatha kubweretsa mawonekedwe mu thupi la zovuta za metabolic, zomwe zimawonetsedwa ndi mawonekedwe a lactic acidosis mu mtundu 2 shuga.
Zotsatira zoyipa zikachitika, mankhwalawo ayenera kusiyidwa ndipo adokotala amalangizidwa za zomwe zasinthazo.
Zizindikiro za mankhwala osokoneza bongo komanso kugwiritsa ntchito mankhwala
Pakakhala kuchuluka kwa Glucofage wodwala yemwe ali ndi matenda a shuga a mtundu wachiwiri, zizindikiro zina zimawonekera.
Mankhwala osokoneza bongo amapezeka pamene Metformin imatengedwa pa mlingo wa 85 g wa mankhwalawo. Mlingo uwu umaposa nthawi yokwanira 42,5. Ndi kuchuluka kwa mlingo wotere, wodwalayo samakhala ndi zizindikiro za hypoglycemia, koma zizindikiro za lactic acidosis zimawonekera.
Pakakhala zizindikiro zoyambirira za lactic acidosis mwa wodwala, mankhwala osokoneza bongo ayenera kusiyidwa, ndipo wodwala ayenera kuchipatala. Pambuyo pachipatala, wodwalayo amayenera kufufuzidwa kuti adziwe kuchuluka kwa lactate komanso kumveketsa bwino matendawa.
Kuti athane ndi thupi la wodwala lactate, njira ya hemodialysis imachitika. Pamodzi ndi njirayi, chithandizo chamankhwala chimachitika.
Ndi zoletsedwa kugwiritsa ntchito mankhwalawa poyesa thupi pogwiritsa ntchito mankhwala okhala ndi ayodini.
Sitikulimbikitsidwa kumwa zakumwa zoledzeretsa pakumwa mankhwalawa ndi Glucophage ndi Glucophage Long.
Ndiosafunika kugwiritsa ntchito mankhwalawa mukamagwiritsa ntchito zakudya zochepa zopatsa mphamvu.
Mosamala muyenera kugwiritsa ntchito mitundu yonse iwiri ya mankhwalawa mukamagwiritsa ntchito mankhwala osokoneza bongo a hypoglycemic.
Mtengo wa Glucofage, womwe uli ndi nthawi yovomerezeka, pafupifupi ma ruble 113 m'dera la Russian Federation, ndipo mtengo wa Glucofage Long uli ku Russia 109 rubles.
Kuchita kwa mankhwala Glucofage akufotokozedwa mwatsatanetsatane ndi katswiri mu kanema munkhaniyi.
Kuyerekezera kwa Glucophage Glucophage Kutalika
Kapangidwe ka mankhwalawa kamasiyana pang'ono, kotero kukula kwa kapangidwe kake ndi chimodzimodzi. Kutalika kumathandiziranso shuga ndikuwongoletsa kagayidwe ka lipid popanda kukhudza insulin. Amawerengetsera chithandizo komanso kupewa matenda ashuga.
Glucophage Long imachepetsa shuga ndikuyenda bwino kwa lipid metabolism osakhudza insulin.
Chikhalidwe chachikulu cha mankhwala ndizomwe zimagwira. Zisonyezero zogwiritsira ntchito - lembani matenda a shuga 2, mellitus, incl. ndi anthu onenepa kwambiri. Pankhaniyi, onsewa mankhwalawa amatha kutumizidwa ngati zolimbitsa thupi komanso kudya sizinapereke zotsatira zomwe mukufuna. Mankhwala onse awiriwa amatha kugwiritsidwa ntchito molumikizana ndi insulin.
Contraindication ogwiritsa ntchito mankhwala onse awiri:
- Hypersensitivity ku chinthu yogwira kapena zinthu zothandizira:
- lactic acidosis
- matenda ashuga ketoacidosis kapena chikhalidwe kapena chikomokere,
- kwambiri matenda opatsirana,
- matenda aliwonse pachimake kapena mawonekedwe osakhazikika, ngati pali vuto la hypoxia,
- kuchepa mphamvu kwa thupi, kuphatikiza kusanza kapena kutsegula m'mimba,
- kuchitapo kanthu kwa maopareshoni ndi kuvulala komwe kumafuna chithandizo cha insulin.
Musamwe mankhwalawa komanso kuwonongeka kwaimpso kapena chiwindi.
Cholepheretsa kuvomereza ndikuti ndi pakati komanso mkaka wa m'mawere, popeza zovuta za mankhwala pakubala kwa mwana sizikumveka bwino.
Mankhwalawa onse ndi oletsedwa kwa ana ndi achinyamata osakwana zaka 18, mosasamala kanthu za kukhalapo kapena kusapezeka kwa kulephera kwa impso kapena zina.
Kodi pali kusiyana kotani pakati pa mankhwala?
Type 2abetes mellitus ndi kusokonezeka kwa kagayidwe ka thupi, momwe kugaya kwa maselo amthupi a mahomoni ena apadera omwe amatchedwa insulin. Chifukwa cha izi, pali kuwonjezeka kwa kuchuluka kwa shuga m'magazi, zomwe zimabweretsa kukula kwa hyperglycemia. Matenda a shuga akayamba, zovuta zotsatirazi zitha kuwoneka - kutayika kwathunthu kapena pang'ono pang'ono, kuwonongeka kwamitsempha yamagazi, kufooka ndi mseru, mapangidwe a mafupa, kuwonjezeka thukuta, kunenepa kwambiri, ndi zina zotero. Pofuna kuchiza matenda a shuga, muyenera kumwa mankhwala apadera omwe amagwiritsa ntchito shuga wambiri ndikuwongolera kulumikizana kwa maselo a thupi ndi insulin. Ndikulimbikitsidwanso kuti muzitsatira zakudya zapadera ndikuchita masewera olimbitsa thupi kuti muchepetse kuchuluka kwa shuga ochulukirapo.
Chimodzi mwa mankhwala othandiza kwambiri polimbana ndi hyperglycemia ndi Glucophage ndi Glucophage Long. Mankhwalawa amathandizira kulumikizana kwa insulin ndi maselo amthupi, zomwe zimapangitsa kukonzanso kwa shuga mthupi.
Chithandizo choterechi chimathandizanso kuchepetsa kagayidwe ka mafuta, chifukwa chake Glucofage ndi Glokofage Long zitha kugwiritsidwa ntchito pochiza kunenepa kwambiri ndi hyperglycemia. Nthawi zina, mankhwalawa amathanso kugwiritsidwa ntchito pochiza kunenepa kwambiri, komwe sikunayambike chifukwa cha matenda ashuga, koma Mulimonsemo, mankhwalawo amayenera kuvomerezana ndi adotolo, chifukwa kudzipereka kungakhale kovulaza. Nthawi yomweyo, muyenera kumvetsetsa kuti kukonzekera kwa Glucofage ndi Glucophage Long ndizofanana kwambiri wina ndi mzake muzipatala zawo (mawonekedwe omwewo omasulidwa, za mulingo womwewo ndi zina zotero), komabe, pali kusiyana pang'ono.
Kusiyana kwakukulu pakati pa Glucofage Long ndiko kukhalapo kwa owonjezera omwe amakhudza kagayidwe ka mankhwala ndi bioavailability wa mankhwalawa. Glucofage idapangidwa kuti ikhale yothandiza kwakanthawi kochepa, chifukwa pomwe kutsika kwamphamvu kwa shuga mumagazi kumachitika, pomwe Glucofage imaledzedwa kuti ikwaniritse zotsatira zazitali za kuchepetsa shuga. Mankhwala a mankhwala ena ake zimatengera umunthu wa thupi kuti thupi lake lizigwira bwino ntchito. Tiyenera kumvetsetsa kuti malinga ndi magawo awo ofunikira, mankhwalawa ndi ofanana kwambiri, ndipo kugwiritsa ntchito mankhwala ena kumakhala ndi zotsatirazi zina mthupi:
- Sinthani magulu a shuga,
- Kuwongolera kulumikizana kwa insulin ndi maselo amthupi,
- Matenda a metabolism yamafuta ndi kuchotsa mafuta ochulukirapo m'thupi,
- Kuchepetsa kuchuluka kwa mafuta m'thupi m'magazi, zomwe zimathandiza kupewa matenda a mtima.
Kuphatikizika ndi kufunikira kwake
Glucophage ndi Glucophage Long ndizofanana pakapangidwe, ngakhale pali zosiyana zina zomwe zimapangitsa kusiyana pakumwa izi kapena mankhwalawa. Chofunikira chachikulu pa mankhwala onsewa ndi metformin hydrochloride. Panthawi ya makonzedwe, chinthuchi chimasinthidwa m'mimba kukhala metformin. Kenako chinthuchi chimalowa m'matumbo, pomwe chimalowa mu magazi.Pambuyo pake, thupilo limalowa m'chiwindi, komwe limachepetsa kaphatikizidwe ka shuga, kamene kamayambitsa kuchepa kwa shuga m'magazi. Chifukwa cha izi, ntchito yamakonzedwe onse amkati amkati imakhala yofanana, ndipo zizindikiro za mtundu wachiwiri wa matenda ashuga zimatha. Tsoka ilo, zovuta zomwe zimagwiritsidwa ntchito ndi metformin ndizakanthawi kochepa, chifukwa chake, pofuna kupewa matenda a shuga, muyenera kumwa Glucophage kapena Glucophage Long moyo. Kuchulukitsidwa kwa metformin ku Glucofage Long kumakulirapo, chifukwa chake kugwiritsa ntchito mankhwalawa ndikutali.
Glucophage imaphatikizanso povidone ndi zinthu zina. Amawonjezera bioavailability wa mankhwalawa, zomwe zimapangitsa kutsika kwamphamvu kwa glucose. Glucofage Long imaphatikizanso cellulose, mchere wa sodium ndi zinthu zina. Izi zimapangitsa pang'onopang'ono kuchepa kwa chinthu chachikulu chomwe chimagwira m'mimba, chifukwa chake Glucofage Long imathandizanso kulimbitsa thupi. Kusiyanitsa miyala ndi inzake, mapiritsi a Glucophage wamba amapangidwa mozungulira, ndipo Glucophage wa Long ndi chowulungika. Mankhwalawa amapezeka m'matumba a mapiritsi 10-20, ndipo piritsi limodzi lili ndi 500 mg yofunikira.
Pankhani yogwiritsa ntchito nthawi yayitali ya Glucofage kapena Glucophage Long, mafuta amapezeka modabwitsa, omwe nthawi zambiri amakhala ndi vuto la matenda ashuga a 2. Chifukwa cha izi, munthu amayamba kuwotcha zopatsa mphamvu zochulukirapo, zomwe zimapangitsa kuti achepetse thupi.
Kuchepetsa thupi kumadalira gawo la kukula kwa matenda ashuga, zaka za munthu, momwe munthu akuonekera, kuchuluka kwa mankhwalawa, ndi zina zambiri, koma nthawi zambiri mothandizidwa ndi Glofofage kapena Glucofage Long, mutha kutaya makilogalamu 1-4 pa sabata.
Nthawi zina, mankhwalawa amatha kuledzera kuti muchepetse thupi, ngakhale munthuyo atakhala kuti alibe matenda ashuga. Komabe, izi zikuyenera kuchitika pokhapokha atakambilana ndi adotolo, popeza pankhani ya mankhwala omwe mumalandira mankhwala omwe ali ndi vuto lachipatala ndiwokwera kwambiri, zomwe zingayambitse kusokoneza ziwalo zamkati.
Momwe mungamwe kumwa Glucofage?
Glucophage imapezeka mu mawonekedwe a mapiritsi akumeza. Muyenera kumwa mapiritsi nthawi yakudya kapena itatha. Kuti mumwe mankhwalawa, muyenera kumwa madzi ambiri kuti piritsi limalowe m'mimba ndipo lisamatengeke m'mero. Mlingo wa mankhwalawa zimatengera magawo monga kukula kwa matendawo, zaka, machitidwe a thupi, kuchuluka kwa chiwindi, ndi zina zambiri. Nthawi zambiri, mankhwalawa amaledzera m'mapiritsi a 1-2 ndipo patsiku (500-1,000 mg wa metformin) nthawi imodzi kuonetsetsa kuti magazi achepetsa magazi.
Ngati mankhwalawa alibe othandizira, ndiye kuti muyezo wake ungathe kuwonjezeka ndi 1.5-3 nthawi. Nthawi yomweyo, nthawi imodzi, munthu sayenera kumwa zosaposa 1.000 mg za metformin, ndipo mlingo waukulu wa tsiku ndi tsiku ndi 3.000 mg wa metformin.
Mankhwalawa amathanso kugwiritsidwa ntchito ndi ana opitirira zaka 10 moyang'aniridwa ndi dokotala. Pa nthawi yoyembekezera komanso pakubala, mankhwalawa amayenera kugwiritsidwa ntchito mosamala, komanso kudziwa mulingo woyenera wa mankhwalawo, dokotala amathanso kukuwuzani mayeso owonjezera.
Momwe mungamwe kumwa Glucofage Long?
Glucophage Long imapezekanso m'njira yam'meza. Ndi bwino kumwa mankhwalawo kamodzi pachakudya kawiri pa tsiku (m'mawa ndi madzulo). Sitikulimbikitsidwa kumwa mankhwalawa musanadye kapena mutamaliza kudya, chifukwa izi zimachepetsa achire a metformin. Mlingo wa mankhwalawa zimatanthauzanso magawo ambiri (mawonekedwe amomwe thupi limakhalira, magawo a chitukuko cha matendawa, ndi zina zambiri), komabe, nthawi zambiri amamwa mankhwalawa 500 mg tsiku lililonse kwa masabata awiri oyamba, ndipo atatha nthawi imeneyi mlingo umatha kuchuluka ndi 1.5- 2 nthawi ngati osauka achire. Glucophage Long imakonzedwa pang'onopang'ono ndi thupi, motero mankhwalawa amalembedwa kwa amayi apakati, ana osakwana zaka 18 ndi anthu omwe ali ndi matenda a impso.
Pomaliza
Mwachidule. Glucophage ndi Glucophage Long ndi mankhwala awiri ochizira matenda a shuga a 2 komanso matenda ena.
Mankhwala onse awiriwa amapezeka mu mawonekedwe a mapiritsi, kulandiridwa kwake komwe kuyenera kuvomerezana ndi adokotala. Kuti mutenge, muyenera kuyika piritsi pakamwa panu ndi kumamwa ndi madzi ambiri kuti mankhwalawo asatonongeke mu esophagus. Tiyeneranso kukumbukira kuti mu matenda a shuga a mellitus lipid amachepa, chifukwa chake, mukamalandira chithandizo ndi Glucofage kapena Glucofage Long, mutha kutaya makilogalamu a 1-4 pa sabata, komabe, kumwa mankhwalawa pofuna kuchepetsa thupi pakalibe shuga kumavomerezedwa pokhapokha ngati muli ndi chilolezo chadokotala.
Zomwe zili bwino - Glucofage kapena Glucofage Long?
Metformin (Glucophage) imakhala ndi zoyipa. Amapezeka mu 25% ya odwala omwe amagwiritsidwa ntchito mankhwalawa kwa nthawi yayitali, ndipo makamaka izi ndizotsatira zosayenera kuchokera kugaya chakudya. Mu milandu ya 5-10%, chifukwa cha izi, ndikofunikira kuletsa mankhwalawa.
Kuopsa kwa zoyipa zimachepetsedwa, mwachitsanzo, ngati dokotala angasinthe kuchuluka kwa tsiku lililonse. Mu nthawi yayitali, zovuta zoyipa zimachepetsedwa.