Malangizo ogwiritsira ntchito mankhwala a Torvacard ndi mawonekedwe ake

Pochiza matenda a shuga, sikuti mankhwalawa omwe amakhudza kuchuluka kwa shuga m'magazi omwe amagwiritsidwa ntchito.

Kuphatikiza pa izi, dokotala angakupatseni mankhwala omwe amathandizira kuchepetsa mafuta m'thupi.

Chimodzi mwa zinthu zoterezi ndi Torvacard. Muyenera kumvetsetsa momwe zingakhalire zothandiza kwa odwala matenda ashuga komanso momwe angazigwiritsire ntchito.

Zambiri, kapangidwe, mawonekedwe omasulira

Statin Cholesterol Kuletsa

Chida ichi ndi amodzi mwa ma statins - mankhwala ochepetsa cholesterol yamagazi. Ntchito yake yayikulu ndikuchepetsa kuchuluka kwa mafuta mthupi.

Amagwiritsidwa ntchito bwino kupewa komanso kuthana ndi atherosulinosis. Kuphatikiza apo, Torvacard imatha kuchepetsa shuga m'magazi, ndizofunikira kwa odwala omwe ali pachiwopsezo chokhala ndi matenda ashuga.

Maziko a mankhwalawa ndi mankhwala Atorvastatin. Zimaphatikizika ndi zosakaniza zowonjezera zimatsimikizira kukwaniritsa zolinga.

Amapangidwa ku Czech Republic. Mutha kugula mankhwalawa mwa mtundu wa mapiritsi. Kuti muchite izi, muyenera kulandira mankhwala kuchokera kwa dokotala.

Gawo lothandizirali limakhudza kwambiri momwe wodwalayo alili, chifukwa chake kudzilimbitsa nokha ndikosavomerezeka. Onetsetsani kuti mwalandira malangizo enieni.

Mankhwalawa amagulitsidwa mu mawonekedwe a mapiritsi. Chofunikira chawo ndi Atorvastatin, kuchuluka kwake komwe gawo lililonse likhoza kukhala 10, 20 kapena 40 mg.

Imathandizidwa ndi zida zothandizira zomwe zimathandizira kupititsa patsogolo ntchito ya Atorvastatin:

• magnesium oxide
• cellcrystalline mapadi,
• silicon dioxide
• sodium croscarmellose,
• lactose monohydrate,
• olimba ndi magnesium,
• hydroxypropyl cellulose,
• talcum ufa
• macrogol
• titanium dioxide
• hypromellose.

Mapiritsiwo ali ndi mawonekedwe ozungulira komanso oyera (kapena pafupifupi) oyera. Amayikidwa m'matumba a ma PC 10. Phukusili limatha kukhala ndi matuza atatu kapena 9.

Pharmacology ndi pharmacokinetics

Kuchita kwa atorvastatin ndiko kuletsa enzyme yomwe imapanga cholesterol. Chifukwa cha izi, kuchuluka kwa cholesterol kumachepetsedwa.

Maselo a cholesterol amayamba kugwira ntchito mwachangu, chifukwa chomwe pawiri womwe umapezeka m'magazi umadyedwa mwachangu.

Izi zimalepheretsa mapangidwe a ma atherosselotic amana mu ziwiya. Komanso, motsogozedwa ndi Atorvastatin, kuchuluka kwa ma triglycerides ndi glucose kumachepa.

Torvacard imachitika mwachangu. Mphamvu ya gawo lake yogwira ntchito imafika pamlingo waukulu pambuyo pa maola 1-2. Atorvastatin pafupifupi imafanana ndi mapuloteni a plasma.

Kupanga kwake kumachitika m'chiwindi ndikupanga metabolites yogwira. Zimatenga maola 14 kuti zithetse. Thupi limachoka m'thupi ndi bile. Zotsatira zake zimapitirira kwa maola 30.

Zizindikiro ndi contraindication

Torvacard akulimbikitsidwa pazotsatirazi:

• cholesterol yayikulu
• kuchuluka triglycerides
• hypercholesterolemia,
• matenda a mtima komanso chiwopsezo cha matenda a mtima,
• kuthekera kwa yachiwiri myocardial infaration.

Dokotala atha kukulemberani mankhwalawa nthawi zina, ngati kugwiritsidwa ntchito kwake kungathandize kukonza bwino wodwalayo.

Koma chifukwa cha izi ndikofunikira kuti wodwala alibe zotsatirazi:

• matenda akulu a chiwindi
• kuchepa kwa lactase
• lactose ndi glucose tsankho,
• osakwana zaka 18
• tsankho pamagawo ena
• mimba
• kudya kwachilengedwe.

Izi ndizotsutsana, chifukwa chake ntchito Torvacard ndi yoletsedwa.

Komanso, malangizowa amatchula milandu yomwe mungagwiritse ntchito chida ichi pokhapokha ngati mukuyang'aniridwa ndi achipatala:

• uchidakwa
• ochepa matenda oopsa
• khunyu
• kagayidwe kachakudya matenda
• matenda ashuga
• sepsis
• kuvulala kwakukulu kapena opaleshoni yayikulu.

Pazochitika zotere, mankhwalawa angayambitse kusadalirika, motero muyenera kusamala.

Malangizo ogwiritsira ntchito

Ndi pakamwa pokhapokha ngati mankhwalawa amachitika. Malinga ndi malingaliro ambiri, poyambira muyenera kumwa mankhwalawa mu 10 mg. Kuyesedwa kowonjezereka kumachitika, malinga ndi zotsatira zomwe dokotala amatha kuwonjezera mlingo mpaka 20 mg.

Kuchuluka kwa Torvacard patsiku ndi 80 mg. Gawo logwira ntchito kwambiri limatsimikizidwa payekhapayekha pa mlandu uliwonse.

Musanagwiritse ntchito, mapiritsi safunikira kuphwanyidwa. Wodwala aliyense amawatenga pa nthawi yoyenera yake, osaganizira kwambiri chakudya, popeza kudya sikumabweretsa zotsatira zake.

Kutalika kwa chithandizo kumasiyana. Zotsatira zake zimadziwika pambuyo pa masabata awiri, koma zimatenga nthawi yayitali kuti munthu ayambe kuchira.

Nkhani ya kanema yochokera kwa Dr. Malysheva wonena za ma statins:

Odwala Apadera ndi Mayendedwe

Kwa odwala ena, zigawo zikuluzikulu za mankhwalawa zimatha kuchita mosazolowereka.

Kugwiritsa ntchito kumafunika kusamala ndi magulu otsatirawa:

1. Amayi oyembekezera. Panthawi yamatumbo, cholesterol ndi zinthu zomwe zimapangidwa kuchokera pamenepo ndizofunikira. Chifukwa chake, kugwiritsa ntchito atorvastatin panthawiyi ndi kowopsa kwa mwana yemwe ali ndi vuto lakukhazikika. Chifukwa chake, madokotala sawalimbikitsa kuti athandizidwe ndi mankhwalawa.
2. Amayi omwe akuchita zozizwitsa zachilengedwe. Gawo lomwe limagwira ntchito limadutsa mkaka wa m'mawere, zomwe zingakhudze thanzi la mwana. Chifukwa chake, kugwiritsa ntchito Torvacard panthawi yoyamwitsa nkoletsedwa.
3. Ana ndi achinyamata. Momwe Atorvastatin amachitira pa iwo sizikudziwika kwenikweni. Popewa zoopsa zomwe zingachitike, kuikidwa kwa mankhwalawa sikuchotsedwa.
4. Anthu okalamba. Mankhwalawa amawakhudza komanso odwala ena onse omwe alibe zotsutsana ndi mankhwalawa. Izi zikutanthauza kuti kwa odwala okalamba palibe chifukwa chosinthira.

Palibe njira zina zofunika kuzisamalirira.

Mfundo yothandizira pochiritsa imayendetsedwa ndi zinthu monga concomitant pathologies. Ngati lipezeka, nthawi zina pamafunika kusamala kwambiri pakugwiritsa ntchito mankhwala.

Kwa Torvacard, ma pathologies awa ndi:

1. Matenda a chiwindi. Kukhalapo kwawo kuli pakati pa zotsutsana pakugwiritsa ntchito chinthucho.
2. Kuchulukitsa kwa ma seramu transaminases. Mbali iyi ya thupi imaperekanso chifukwa chokana kumwa mankhwalawa.

Zovuta pa ntchito ya impso, zomwe nthawi zambiri zimaphatikizidwa mndandanda wazotsutsana, sizimawonekeranso nthawi ino. Kukhalapo kwawo sikukhudza zotsatira za Atorvastatin, kotero kuti odwala oterowo amaloledwa kumwa mankhwala ngakhale osasintha mlingo.

Chofunikira kwambiri ndikugwiritsa ntchito njira zodalirika zakulera pothandizira amayi omwe ali ndi zaka zakubala. Panthawi ya utsogoleri wa Torvacard, kuyambika kwa pakati pa mimba sikovomerezeka.

Zotsatira zoyipa ndi bongo

Mukamagwiritsa ntchito Torvacard, zotsatira zotsatirazi zingachitike:

• mutu
• kusowa tulo
• Kukhumudwa
• nseru
• zosokoneza mu ntchito ya m'mimba,
• kapamba
• kuchepa kwamtima
• kupweteka kwa minofu ndi molumikizana
• kukokana
• anaphylactic shock,
• kuyabwa
• zotupa pakhungu,
• mavuto azaku kugonana.

Ngati izi ndi zotsutsana zina zadziwika, muyenera kufunsa dokotala ndikufotokozerani vutoli. Kuyesa kudziyimira pawokha kumatha kubweretsa zovuta.

Mankhwala osokoneza bongo ogwiritsa ntchito mankhwalawa molondola ndiwokayikitsa. Zikadzachitika, symptomatic mankhwala amasonyezedwa.

Kuchita ndi mankhwala ena

Pofuna kupewa zoyipa za thupi, ndikofunikira kuganizira za zovuta zomwe zimachitika ndi mankhwala ena a Torvacard.

Kusamala ndikofunikira pakugwiritsa ntchito limodzi ndi:

• Erythromycin
• ndi antimycotic othandizira
• mafupa
• Cyclosporine
• nicotinic acid.

Mankhwalawa amatha kuwonjezera kuchuluka kwa atorvastatin m'magazi, chifukwa chomwe chiopsezo cha mavuto.

Ndikofunikanso kuwunika mosamala momwe chithandizo chikuyendera ngati mankhwala monga awonjezeredwa ku Torvacard:

• Colestipol,
• Cimetidine
• Ketoconazole,
• kulera kwamlomo
• Digoxin.

Kuti apange njira yoyenera yolandirira, dokotala ayenera kudziwa zonse zamankhwala zomwe wodwala akutenga. Izi zipangitsa kuti iye aziwona bwinobwino chithunzichi.

Mwa mankhwala omwe ali oyenera kusintha mankhwalawo Njira zitha kutchedwa:

Kugwiritsa ntchito kwawo kuyenera kuvomerezedwa ndi adokotala. Chifukwa chake, ngati pakufunika kusankha mapikisano otsika mtengo a mankhwalawa, muyenera kulumikizana ndi katswiri.

Malingaliro odwala

Ndemanga za mankhwala a Torvakard ndizotsutsana - ambiri adabwera ndi mankhwalawa, koma odwala ambiri adakakamizidwa kuti akane kumwa mankhwalawa chifukwa cha zoyipa, zomwe zimatsimikiziranso kuti pakufunika kufunsa dokotala ndikuwunika momwe amagwiritsidwira ntchito.

Ndakhala ndikugwiritsa ntchito Torvacard zaka zingapo. Chizindikiro cha cholesterol chatsika ndi theka, mavuto sanachitike. Dokotalayo adatinso kuyesa njira ina, koma ndidakana.

Ndili ndi zovuta zambiri kuchokera ku Torvacard. Kupweteka kwambiri m'mutu, nseru, kukokana usiku. Adavutika kwa milungu iwiri, kenako adapempha adotolo kuti athetse mankhwalawa ndi china.

Sindinawakonde mapiritsi awa. Poyamba zonse zinali molongosoka, ndipo patatha mwezi umodzi zovuta zinayamba kulumpha, kusowa tulo komanso kupweteka kwambiri m'mutu kunawonekera. Adotolo adati mayesowa adakhala bwino, koma inenso ndidamva bwino. Ndidayenera kukana.

Ndakhala ndikugwiritsa ntchito Torvard kwa miyezi isanu ndi umodzi tsopano ndipo ndikusangalala kwambiri. Cholesterol ndiyabwinobwino, shuga yachepa pang'ono, kupanikizika kwabwerera mwakale. Sindinazindikire mavuto aliwonse.

Mtengo wa Torvacard umasiyana malinga ndi kuchuluka kwa Atorvastatin. Mapiritsi 30 a 10 mg, muyenera kulipira ma ruble 250-330. Kugula phukusi la mapiritsi 90 (20 mg) pamafunika ma ruble 950-1100. Mapiritsi okhala ndi zinthu zapamwamba kwambiri zogwira ntchito (40 mg) amawononga ma ruble 1270-1400. Phukusili lili ndi ma PC 90.

Kodi atherosulinosis ndi chiani ndipo ndi chiani?

Atherosulinosis ndi matenda am'magazi oyambitsidwa ndi kupangika kwa cholesterol plaque mkati mwa mitsempha yayikulu, yomwe imatsogolera pakukhazikitsidwa kwa matenda oopsa omwe ali pachiwopsezo cha moyo:

• Mloza wamagazi wambiri,
• Matenda a mtima ziwalo tachycardia, arrhythmia ndi angina pectoris,
• Myocardial infaration ndi ubongo infaration,
• Hemorrhagic mtundu wa sitiroko,
• Atherosulinosis ya miyendo imayambitsa gangore ndikudula.

Zowopsa zimayambitsa kuchuluka kwa cholesterol index m'magazi ndi ma lipoprotein ochepa a LDL ndi VLDL.

Kuchepetsa kuchuluka kwa osachulukitsa miloproteins ndi kukwera kwamphamvu maselo ochulukitsa lipoprotein m'magazi, kumachepetsa mwayi wokhala ndi systemic atherosulinosis.

Mapulogalamu a gulu la ma statins omwe amalepheretsa kusintha kwa HMG-CoA reductase, omwe amapanga mevalonic acid m'maselo a chiwindi, amathandizira kusintha magawo a lipoprotein, omwe amachititsa kuchuluka kwa lipoproteins ochepa.

Woimira gulu la ma Torvacard a statins amatha kutsitsa cholesterol yoyipa yomwe ili ndi ma pathologies:

• Matenda a shuga
• Ndi matenda oopsa
• Ndi chiwopsezo chachikulu chotengera mtima wa mtima.

Chosakaniza chophatikizira mu statin Torvacard ndi atorvastatin, chomwe chimatsitsa:

• Mndandanda wonse wa cholesterol m'mwazi ndi 30.0% 46.0%,
• Kuchuluka kwa ma molekyulu a LDL pa 40.0% 60.0%,
• Pali kuchepa mu index ya triglyceride.

Atherosulinosis

The zikuchokera gulu la mankhwala a statins Torvard

Torvacard imapangidwa ngati mawonekedwe a mapiritsi ozungulira ndi ophatikizika mu chipolopolo chomwe chili ndi gawo lalikulu la atorvastatin mu kipimo cha mamiligamu 10,0, mamiligalamu 20.0, mamiligalamu 40.0.

Kuphatikiza pa atorvastatin, mapiritsi a Torvacard akuphatikizapo:

• Microcrystalline cellulose mamolekyulu,
• Magnesium wakuba ndi zopondera,
• Ma molekyulu sodium a Croscarmellose,
• Hypromellose ndi lactose,
• Silika ion
• Titanium diayoni,
• Mankhwala macrogol 6000.0,
• Talc.

Mankhwala a Torvacard ndi zofananira zake mu pharmacy network zimangogulitsidwa pokhapokha kuchokera kwa adokotala.

Croscarmellose sodium

Fomu lotulutsira mankhwala a Torvard

Mapiritsi a Torvacard statin amapezeka m'matumba a zidutswa za 10,0 ndipo amaikidwa m'makatoni ama 3, kapena matuza 9. Mu bokosi lirilonse, wopanga mapiritsi amaika malangizo ogwiritsira ntchito, popanda kuwerenga zomwe simungayambe kumwa Torvacard.

Mtengo wa mankhwalawo mumagulu azachipatala amatengera mlingo wa gawo lalikulu la atorvastatin komanso kuchuluka kwa mapiritsi omwe ali phukusi, komanso dziko lakapangidwe.

Ma analogu aku Russia ndiotsika mtengo:

Ku Russia, mutha kugula fanizo la Torvacard wotsika mtengo kwa wopanga waku Russia, mwachitsanzo, mankhwalawa Atorvastatin pamtengo wokwera mpaka ma ruble 100 aku Russia.

Analogue iyi ndi mitengo yotsika mtengo kwambiri.

Mankhwala

Torvacard ndi mankhwala opangidwa ndi gulu la statin, lomwe cholinga chake ndikulepheretsa kuchepa kwa HMG-CoA kuchepetsa malire a cholesterol yonse. Magazi amakhala ndi cholesterol m'magawo onse.

Torvacard, chifukwa cha gawo lake lalikulu la atorvastatin, amachepetsa kuyika uku m'magazi:

• Chiwonetsero chonse cha cholesterol,
• Ma molekyulu otsika kwambiri a lipoprotein,
• Mapoprotein otsika kwambiri,
• Ma triglyceride mamolekyulu.

Kuchita kwa statin Torvakard kumachitika ngakhale ndi kukula kwa ma genetic pathologies awa:

• Homozygous ndi heterozygous cholowa chibadwa hypercholesterolemia,
• Maphunziro oyambira a hypercholesterolemia,
• Matenda osakanikirana a dyslipidemia.

Matupi obadwa m'mabanja satsatira bwino chithandizo chamankhwala ena.

Torvacard imatha kuchita maselo a chiwindi kuti ichulukitse kapangidwe ka miloproteins yapamwamba kwambiri, yomwe imachepetsa chiopsezo chotenga matenda oterewa m'thupi ndi m'magazi.:

• Angina osakhazikika ndi ischemia ya mtima
• Myocardial infaration
• Mitundu ya Ischemic ndi hemorrhagic
• Thrombosis yamitsempha yayikulu,
• Systemic atherosulinosis.

Mlingo wa tsiku ndi tsiku wa mankhwala a Torvakard amasankhidwa ndi adotolo pamaziko a magawo a Laborator ndi mawonekedwe a munthu wodwala.

Mlingo wa tsiku ndi tsiku wa mankhwala a Torvacard amasankhidwa ndi dokotala

Pharmacokinetics

Mankhwala a pharmacokinetics a group la Torvacard a statins samatengera nthawi yomwe amatenga mapiritsi ndipo sanamangidwe ku chakudya:

• Njira yoyamwa ya mankhwala ndi thupi. Madzi am'mimba amapezeka m'matumbo am'mimba ndipo mutamwa mapiritsi ambiri, mumitsempha yambiri m'magazi 1 maola awiri. Mlingo wa mayamwidwe umadalira kuchuluka kwa chophatikizira piritsi la Torvacard. The bioavailability ya mankhwalawa ndi 14.0%, ndipo zoletsa zomwe zimapangitsa kuti reductase ikhale 30.0%. Ngati mankhwalawa agwiritsidwa ntchito madzulo, ndiye kuti cholesterol index yonseyo imachepetsedwa ndi 30.0%, ndipo nthawi yoyendetsera sikudalira chisonyezo chotsitsa kachigawo kakang'ono kwambiri ka kulemera,
• Kugawa kwa yogwira mankhwala a atorvastatin mthupi. Zoposa 98.0% zogwira ntchito za atorvastatin zimamanga mapuloteni.Kafukufuku wokhudzana ndi mankhwalawa adawonetsa kuti atorvastatin imadutsa mkaka wa m'mawere, womwe umaletsa kumwa Torvacard pamene mayi ayamwitsa mwana,
• Kagayidwe kachakudya. Metabolism imachitika kwambiri komanso ma metabolites amakhala ndi mphamvu zoposa 70.0% ya zoletsa zomwe zimapangitsa kuti achulukane,
• Kuchotsa zotsalira za chinthu kunja kwa thupi. Mbali yayikulu (mpaka 65.0%) yogwira ntchito ya atorvastatin imatulutsidwa kunja kwa thupi ndi bile acid. Hafu ya moyo wa mankhwalawa kwa maola 14. Mu mkodzo, palibe oposa 2.0% ya atorvastatin omwe amadziwika. Mankhwala ena onse amamuchotsera ndowe,
• Makhalidwe ogonana pazotsatira za Torvacard, komanso zaka za wodwalayo. Kwa odwala okalamba, kuchuluka kwa kutsitsa kwa ma molekyulu a LDL ndiwokwera kuposa amuna azaka zazing'ono. M'magazi achikazi, kuchuluka kwa mankhwalawa Torvacard ndikokulira, ngakhale izi sizikuthandiza pakuchepetsa kwa gawo la LDL. Torvacard sanapatsidwe ana ochepera zaka zambiri,
• Matenda a impso. Kulephera kwa ziwalo zam'mimba, kapena ma pathologies a impso sikukhudza kuchuluka kwa atorvastatin m'magazi a wodwala,, motero, kusintha kwa tsiku ndi tsiku sikofunikira. Atorvastatin imamangiriza kwambiri mapuloteni, omwe samakhudzidwa ndi njira ya hemodialysis,
• Matenda a maselo a chiwindi. Ngati hepatic pathologies imagwirizanitsidwa ndi kudalira kwa mowa, ndiye kuti gawo logwira ntchito la atorvastatin limakulitsidwa kwambiri m'magazi.

Pharmacokinetics ya mankhwala a Torvacard gulu la ma statins sizitengera nthawi yomwe mumamwa mapiritsi

Kuchita ndi mankhwala ena

Zomwe zawonetsedwa pazowerengera peresenti ndikusiyana kwa deta yokhudza kugwiritsidwa ntchito kwa Torvacard padera. AUC - dera lomwe lili pansi pa mpendero woonetsa nthawi ya atorvastatin kwakanthawi. C max - zomwe zimakhala kwambiri m'magazi.

Kuphatikizika kwa Torvacard ndi mawonekedwe ake ndi mankhwalawa kungapangitse chiopsezo chokhala ndi mafupa am'mimba minofu ya rhabdomyolysis:

• Mankhwala cyclosporin,
• Mankhwalawa ndi styripentol,
• Phatikizani ma statin omwe ali ndi telithromycin ndi clarithromycin,
• Mankhwala Delavirdine,
• Ketocanazole ndi Voriconazole,
• Mankhwala Posaconazole ndi Itraconazole,
• Vuto loletsa kachilombo ka HIV.

Kuphatikizika kwa Torvacard ndi mawonekedwe ake ndi mankhwala oterewa kumatha kuyambitsa chiopsezo cha kukulitsa mafupa am'mimba

Mankhwala Torvacard ndi mayendedwe ake

Mankhwala a Torvacard ndi mawonekedwe ake amafanana ndi kupewa kwachiwiri:

• Pakadutsa infaration nthawi,
• Pambuyo pa ischemic ndi hemorrhagic stroke,
• Pambuyo pochotsa thrombosis mu matenda a thrombosis.

Torvacard ndi mawonekedwe ake amafotokozedwanso kuti ateteze kukula kwa atherosulinosis ndi mtima pathologies, mwa odwala omwe ali ndi chiopsezo:

• Ukalamba
• Kuledzera
• Kusuta fodya
• Ndi ochepa matenda oopsa.

Fotokozerani mankhwala Torvakard, kapena chifanikidwe cha matenda oterewa m'thupi la munthu:

• Mndandanda wapamwamba wa apoliprotein B, komanso kuchuluka kwa mafuta m'thupi kwambiri komanso kachigawo kakang'ono kwambiri, kamene kamapezeka mu triglycerides m'magazi a magazi aubongo ndi achiwiri mukamagwiritsidwa ntchito limodzi ndi zakudya,
• Mndandanda wokwanira wa ma triglyceride mamolekyu amtundu 4 (gulu la Fredrickson), mankhwala ena akapanda kugwira ntchito,
• Ndi matenda, lembani 3 dysbetalipoproteinemia (gulu la Fredrickson),
• Ndi mtima pathologies okhala ndi chiopsezo cha mtima organ ischemia.

Contraindication Torvacard kapena mayendedwe ake

Osatipatsa mankhwala a Torvacard, komanso mawonekedwe ake pazinthu zotere:

• Kukhudzika kwambiri kwa thupi pazinthu zomwe zili m'mapiritsi,
• Matenda a maselo a chiwindi ndi kuchuluka kwa milomo ya transminase,
• Kulephera kwa chiwindi kwa ana aang'ono (kalasi A kapena B),
• Congenital pathologies a lactose tsankho,
• Amayi azaka zosabereka popanda kubereka moyenera,
• Amayi oyembekezera ndi amayi oyamwitsa,
• Kukula mwana wako mpaka azaka 18.

Njira yogwiritsira ntchito statin Torvakard, kapena analogue ndi kipimo cha tsiku ndi tsiku

Nthawi yovomerezeka kwambiri yokhudza mapiritsi a Torvacard, kapena fanizo lake, isanagone, chifukwa usiku, kuchuluka kwa cholesterol ndizofunikira kwambiri.

Njira yonse ya kumwa mankhwalawa ndi mankhwala a Torvacard ndi mankhwala omwe amayenera kutsagana ndi chakudya chamafuta.

Mlingo watsiku lililonse wa mapiritsi ndi kulondola kwa makonzedwe awo:

• Pa gawo loyambirira la mankhwalawa, muyezo wa mamiligamu 10,0, kapena mamilimita 20.0, umayikidwa, kutengera milomo.
• Ngati mungafunike kutsitsa mndandanda wa ma molekyulu a LDL ndi 45.0% 50.0%, ndiye kuti mutha kuyamba kulandira chithandizo cha mankhwala a 40.0 milligrams patsiku. Kuti achepetse cholesterol mwachangu, dokotala iyemwini amasankha mankhwala ogwiritsa ntchito Torvacard, kapena Atorvastatin (analogue yaku Russia),
• Mlingo woyenera wovomerezeka wa mankhwalawa komanso mawonekedwe akewo sayenera kupitirira mamiligalamu 80.0,
• Kusintha mankhwalawo ndi analogue sikungachitike popanda masiku 30 mutangoyamba kumene chithandizo chamankhwala. M'malo mwake mumapangidwa ngati mankhwalawo sakusonyeza chithandizo chofunikira, kapena kuvulaza thupi la wodwalayo. Ndikofunikira kukaonana ndi dokotala pazotsatira zoyipa, ndipo apeza kuchokera pazofanizira kuti ndi bwino kusintha malo mwa Torvacard,
• Osagwiritsa ntchito Torvacard, kapena ma fanizo ake ngati mankhwala
• Pochiza ndi ma statins, munthu sayenera kuyiwala kuti mankhwala a gululi komanso mowa ndi osagwirizana.

Amayi oyembekezera sayenera kugwiritsa ntchito Torvacard

Zofananira zina

Mankhwala, omwe gawo lalikulu ndi atorvastatin, amawonedwa ngati fanizo la Torvacard. Komanso, fanizo la mankhwalawa limatha kukhala mankhwala, momwe gawo lothandizira ndi rosuvastatin.

Izi zikugwirizana ndi m'badwo waposachedwa wa ma statins, pomwe pali zovuta zochepa pa thupi ndi zotsatira zabwino za mankhwala.

Analogs ndi yogwira mankhwala atorvastatin:

• Statin Atoris,
• Analog yaku Russia ya Atorvastatin,
• Mankhwala a Atomax
• Mankhwala Liprimar,
• Mapiritsi a Liptonorm,
• Mankhwala Tulip.

Analogs ndi yogwira mankhwala rosuvastatin:

• Mankhwala Rosuvastatin,
• Mankhwala Crestor,
• Mapiritsi a Rosucard,
• Mankhwala a Roxer
• Mankhwala Rosulip.

Kuphatikizika, mawonekedwe omasulidwa

Atorvastatin - chokhacho chophatikizira ku Torvacard. Zina zotsalira zimafunikira kuti piritsi lipangidwe, kuwonjezera nthawi yake ya alumali, kusintha kugaya kwa mankhwala. Omwe amathandizira: magnesium oxide, cellulose, lactose monohydrate, croscarmellose sodium, hyprolose, silicon dioxide, magnesium stearate, chipolopolo (hypromellose, macrogol, titanium dioxide, talc).

Torvacard ndi piritsi yoyera-yoyera, yokhala ndi chowulungika, chomwe 10, 20, 40 mg ya chinthu chogwira ntchito. Mapaketi a 30, 90 zidutswa amapangidwa.

Zotsatira za pharmacological

Torvacard ndi othandizira a hypolipidemic ochokera ku gulu la ma statins. Chomwe chimagwira, atorvastatin, imatha kuletsa ntchito ya HMG-CoA reductase enzyme. The enzyme imapangitsa wina wa woyamba cholesterol zochita. Popanda icho, njira yodziyimira pansi imasiya. Mafuta a cholesterol ayamba kutsika.

Kuyesera kulipirira kuchepa kwa sterol, thupi limaphwanya LDL "yoyipa" yomwe ili nayo. Mofananamo, imawonjezera kupanga kwa "good" high-density lipoproteins (HDL), yomwe imafunikira kuti iperekenso cholesterol ku chiwindi kuchokera kuzinthu zopota.

Kutenga mapiritsi a Torvacard kumatha kuchepetsa cholesterol ndi 30-46%, LDL - mwa 41-61%, triglycerides ndi 14-33%. Matenda a mtundu wa lipid amathandizira kuchepetsa kukula kwa atherosulinosis. Amakhulupirira kuti cholesterol yokwera ya LDL, komanso HDL yotsika, imachita mbali yake pakukula kwake.

Torvacard amathandiza kuchepetsa LDL mwa odwala homozygous hypercholesterolemia. Njirayi imadalira kumwa kwa mankhwalawa: kukula kwa mankhwalawo, kumapangitsa kuti chidwi chawo chichepe.

Atorvastatin imatengedwa mwachangu ndi thupi. Pakadutsa maora 1-2 pambuyo pa kupangika, mulingo wake m'magazi umafika pazambiri. Mukatenga Torvacard, imakhalabe yogwira kwa maola 20-30.

Mankhwalawa amachotsedwa ndi chiwindi (98%), komanso impso (2%). Chifukwa chake, itha kutumizidwa kwa odwala omwe ali ndi vuto la impso. Koma ndi zovuta za chiwindi, ziyenera kutengedwa mosamala.

Kutsitsa cholesterol, LDL sichidziwike mwachangu. Nthawi zambiri zimatenga masabata awiri kuti zitheke zoyambira. Torvakard amawonetsa mphamvu yayitali atatha masabata anayi kuchokera poyambira kuyang'anira.

Torvacard: Zizindikiro zogwiritsidwa ntchito

Torvacard, monga statin iliyonse, amalembedwa kwa anthu omwe sanathe kusintha cholesterol, LDL yokhala ndi chakudya. Malinga ndi malangizo, Torvacard akuwonetsedwa:

• cholowa homo-, heterozygous hypercholesterolemia kutsitsa cholesterol, LDL, apolipoprotein B, kuwonjezera HDL,
• triglyceridemia,
• dibetalipoproteinemia.

Mwapadera, Torvacard amalembera ana azaka 10 mpaka 17, omwe, atatha kudya mankhwalawa, cholesterol sikhala pansi pa 190 mg / dl kapena LDL pansi pa 160 mg / dl. Chizindikiro chachiwiri chikuyenera kuphatikizidwa ndi cholowa chamtsogolo kapena chitukuko cha matenda amtima kapena kukhala ndi ≥ 2 chiopsezo cha kukula.

Atorvastatin zotchulidwa kupewa matenda a mtima dongosolo. Ndi mawonekedwe asymptomatic a coronary matenda a mtima, anthu omwe ali ndi chiopsezo chambiri chifukwa cha chitukuko chake (kusuta, uchidakwa, matenda oopsa, otsika HDL, cholowa), kuikidwa kwa atorvastatin kumathandiza:

• sinthani mwayi wokhala ndi vuto la mtima, matenda a mtima,
• letsa kuukira kwa angina,
• Pewani opaleshoni kuti mubwezeretse magazi.

Odwala omwe ali ndi matenda a shuga omwe ali pachiwopsezo chokhala ndi matenda a mtima, mankhwalawa adapangidwa kuti achepetse mwayi wokhala ndi vuto la kugunda kwa mtima.

Odwala omwe ali ndi matenda a mtima apamtunda amatenga Torvacard:

• muchepetse chiopsezo cha myocardial infarction, stroke (ndi / popanda kufa),
• Kuchepetsa kuchuluka kwa zipatala chifukwa cha mtima wosakhazikika,
• kupewa angina pectoris.

Njira ya ntchito, Mlingo

Torvacard imatengedwa kamodzi / tsiku, isanachitike, itatha, kapena ndi chakudya. Ndikofunikira kutsatira nthawi yovomerezeka. Piritsi limamezedwa lonse (osafuna kutafuna, osagawana), osambitsidwa ndi madzi ambiri.

Mankhwala a Torvacard amayamba ndi mlingo wochepera. Pambuyo pa milungu 4, adokotala amawunika kuchuluka kwa cholesterol, LDL. Ngati zotsatira zomwe mukufuna sizikwaniritsidwa, mlingowo umakulitsidwa. M'tsogolo, kusintha kwa mankhwala kumachitika pafupipafupi ndi milungu inayi. Mlingo waukulu kwambiri wa Torvacard ndi 80 mg. Ngati kuchuluka kwa atorvastatin sikutheka kusintha mafuta m'thupi, ndiye kuti pali cholengedwa champhamvu kwambiri kapena mankhwala ena omwe ali ndi vuto lofananalo.

Mlingo woyambirira wa Torvacard wochizira odwala omwe ali ndi cholowa hypercholesterolemia, dyslipidemia wosakaniza ndi 10-20 mg / tsiku. Odwala omwe amafunikira kuchepa kwa mafuta m'thupi (oposa 45%) nthawi yomweyo amapatsidwa 40 mg.

Momwemonso chithandizo chotsatira chimatsatiridwa popereka mankhwala a atorvastatin kwa odwala omwe ali ndi matenda amitsempha yamagazi. Malangizo a Torvacard akutsimikiziridwa ndi European Society for Atherosulinosis pazolinga zamankhwala ochepetsa lipid. Amakhulupilira kuti chofunikira kwambiri kuti akhale wopambana ndi kukhala kupindula kwa cholesterol yonse

Malinga ndi malangizo ogwiritsira ntchito Torvacard, mankhwalawa sayenera kutumizidwa kwa odwala omwe ali ndi chidwi cha atorvastatin, zigawo zina za mankhwala kapena ma statins. Odwala omwe ali ndi vuto la lactose ayenera kulabadira kupezeka kwa lactose.

• mu pachimake hepatic pathologies,
• ndi kuchuluka kosalekeza kwamankhwala osachokera,
• ana (kupatula ana omwe ali ndi cholowa cha heterozygous hypercholesterolemia),
• woyembekezera
• kunyambita
• azimayi amisinkhu yosabereka omwe sagwiritsa ntchito njira zodalirika zakulera.

Ngati mayi atenga pakati pamene akumwa Torvacard, mankhwalawo amathetsedwa. Cholesterol ndiyofunika kuti mwana wosabadwayo amakula bwino. Kuyesa pa makoswe kunawonetsa kuti nyama zomwe zikulandila atorvastatin zimabereka ana odwala. Izi zimawoneka ngati akatswiri okwanira kuletsa kugwiritsa ntchito ma statins aliwonse mwa amayi apakati.

Odwala ambiri amafunikira mankhwalawo bwino. Zotsatira zoyipa sizikhudza moyo wabwino, zimadutsa m'masiku angapo kapena masabata. Magulu ena a anthu amalekerera chithandizo chovuta kwambiri. Odwala osakwatiwa amakumana ndi pathologies akulu. Zotsatira zoyipa za Torvacard:

• rhinitis, zilonda zapakhosi,
• thupi lawo siligwirizana
• shuga wamkulu
• mutu
• mphuno
• kuphwanya kwam'mimba thirakiti (kudzimbidwa, gasi, mseru, dyspepsia, kutsegula m'mimba),
• kuphatikiza, kupweteka kwa minofu
• minofu kukokana
• kuchuluka ALT, AST, GGT.

• shuga wochepa
• kuchuluka phindu
• kukomoka
• kusowa tulo
• zolota
• chizungulire
• zovuta zamaganizidwe
• kulawa kosokoneza
• amnesia
• masomphenya osalala
• tinnitus
• kufooka kwa minofu
• kupweteka m'khosi
• kutupa
• kutopa
• malungo
• urticaria, kuyabwa, zotupa,
• leukocyturia,
• kuchuluka kwa glycosylated hemoglobin.

• thrombocytopenia
• mitsempha
• kuwonongeka kwamawonekedwe
• cholestasis
• Edincke's edema,
• dermatitis
• myopathy
• kutupa kwa minofu
• khalokuz
• tenopathy
• kuphwanya mamangidwe.

• anaphylaxis,
• ugonthi
• kulephera kwa chiwindi
• gynecomastia
• matenda am`mapapo matenda.

Torvacard imalembedwa mosamala kwa anthu omwe ali ndi chizolowezi chokhala ndi rhabdomyolysis. Asanayambe chithandizo, komanso nthawi yonseyi, ayenera kuwongolera mtundu wa creatine kinase. Odwala ndi:

• kuwonongeka kwaimpso,
• kusowa kwa chithokomiro (hypothyroidism),
• mavuto obadwa nawo omwe amakhala ndi minofu yamafupa (kuphatikizapo abale),
• myopathy / rhabdomyolysis atatha mbiri ya statins,
• matenda oopsa a chiwindi ndi / kapena uchidakwa.

Njira zoyenera zomwe zimatsatiridwa ziyenera kutsatidwanso kwa anthu achikulire (zopitilira 70), poganizira zovuta zina.

Muyenera kusiya kumwa Torvacard kwakanthawi, kuuza dokotala ngati muli:

• kukokana kosalamulirika
• okwera / otsika potaziyamu amazi,
• kupsinjika kudagwa kwambiri
• matenda akulu
• pa opaleshoni kapena mwadzidzidzi.

Pomaliza

Mankhwala a Torvakard group of statins ndi mankhwala othandizira polimbana ndi mafuta osafunikira komanso oopsa, omwe ali ndi mndandanda waukulu wa analogues, womwe umalola maphunziro a mankhwala.

Mphamvu ya ma statins imachulukitsa chakudya chamafuta. Osagwiritsa ntchito Torvacard ndi fanizo lodzipatsa nokha ndi banja lanu.

Veronika, wazaka 35: Ndinkakhala ndi hypercholesterolemia, ndipo zimapezeka kuti zimayambitsa banja. Ndinayenera kutsitsa cholesterol ndimankhwala osiyanasiyana, komabe adotolo adayima pamapiritsi a Torvakard.

Ndakhala ndikumwa iwo kwa miyezi yambiri, koma zotsatira zoyambirira zomwe ndidamwa mutatha kumwa mapiritsi mwezi umodzi. M'miyezi iyi, cholesterol yanga sikukwera. Torvacard ilibe vuto lililonse pathupi langa.

Svyatoslav, wazaka 46: Ndidapezeka kuti ndadwala matenda a atherosclerosis nditangofika zaka 40, ndipo kuyambira pamenepo ndakhala ndikuphunzira maphunziro a statin. Nthawi zambiri njira yochizira imatha miyezi 10 12, koma kutha kwake kumatha osaposa miyezi isanu ndi umodzi, ndiye cholesterol imawundukanso.

Chaka ndi theka chapitacho, adotolo adandinyankhira mankhwala a Torvakard. Ndidamwa kwa miyezi 5, koma ndidamva kugwira ntchito kwa mankhwalawa patatha mwezi umodzi. Pazaka zonse, cholesterol yanga inali yachilendo, tsopano yayamba kukwera pang'ono, koma popanda kulumpha lakuthwa.