Glformin yokhudza matenda ashuga: ndemanga pakugwiritsa ntchito mankhwalawa

Wothandizira hypoglycemic adapangira kuti azigwiritsa ntchito pakamwa.

Gliformin ali pa rada (Kulembetsa zamankhwala ku Russia).

Kugwiritsa ntchito bwino kwa mankhwalawa kwa mtundu woyamba wa 2 ndikuwatsimikizira.

Musanatenge mapiritsi a Gliformin a matenda a shuga a 2, ndikofunikira kuwerenga malangizo oti mugwiritse ntchito, komanso mtengo, ndemanga ndi mayendedwe.

Makalata ochokera kwa Owerenga

Agogo anga akhala akudwala matenda a shuga kwa nthawi yayitali (mtundu 2), koma posachedwa zovuta zapezeka m'miyendo ndi ziwalo zamkati.

Mwangozi ndidapeza nkhani pa intaneti yomwe idapulumutsa moyo wanga. Ndidalumikizidwa kumeneko kwaulere pafoni ndipo ndidayankha mafunso onse, ndikuuzidwa momwe ndingachitire ndi matenda ashuga.

Patatha milungu iwiri atatha kulandira chithandizo, agogo aja adasinthiratu momwe akumvera. Ananenanso kuti miyendo yake sikupweteka komanso zilonda zake sizinayende; sabata yamawa tidzapita ku ofesi ya dotolo. Falitsa ulalo wa nkhaniyo

Zizindikiro zogwiritsidwa ntchito

Musanayambe kumwa mankhwalawa, ndikofunikira kuti muphunzire zomwe Glyformin 1000/50/500 ndi, momwe mumaloledwa kumwa mapiritsi.

Mapiritsi amalembedwa kwa odwala omwe samadwala matenda a shuga. Mankhwalawa amaperekedwa kwa odwala pakalibe chithandizo chamankhwala.

Ntchito ngati monotherapy kapena molumikizana ndi mankhwala ena a hypoglycemic. Pankhani ya shuga wodalira insulin, imayikidwa limodzi ndi insulin.

Ndikulimbikitsidwa kumwa mapiritsi a odwala omwe ali ndi vuto lodana ndi sulfonylurea.

Kutulutsa Fomu

Mankhwala amapezeka piritsi la mapiritsi osiyanasiyana. Mapiritsi a 500/8/10000 mg akupezeka ogulitsa.

Wogulitsa mumtsuko wa polypropylene kapena katoni.

Mtengo wa Glformin ndi ma ruble 182- 287.

Kuzindikira kwa shuga - ingomwani tsiku lililonse.

INN Gliformina - METFORMIN. Mankhwalawa amapangidwa ku Russia, mzinda wa Akrikhin.

Chofunikira chachikulu ndi metformin (C₄H₁₁N₅).

Gliformin ilinso ndi zida zothandizira. Izi zikuphatikiza (C6H9NO) n (povidone), C2nH4n + 2On + 1 - polyethylene glycol, Ca3 (PO4) 2 - orthophosphate calcium, CH3 (CH2) 16COOH - stearic acid, C6H14O6 - sorbitol.

Malangizo ogwiritsira ntchito

Mlingo wa mankhwalawa amasankhidwa payekha. Muyenera kudziwa momwe mungatengere Glformin. Amatengedwa pakamwa malinga ndi mlingo womwe waperekedwa.

Malangizo ogwiritsira ntchito Gliformina:

• ½ piritsi kawiri pa tsiku kwa masiku atatu,
• ndiye piritsi 3 katatu pakadutsa maola 24 masiku atatu.

Njira zamankhwala zimapangidwira masiku 15. Pambuyo masiku 6, mlingo umasinthidwa kutengera zotsatira za kusanthula.

Mukakana kumwa mankhwalawo, musataye nthawi yomweyo. Ndikofunikira pang'onopang'ono kuchepetsa mlingo. Zimatenga masiku 5 mpaka milungu iwiri.

Zolemba ntchito

Ana kuyambira wazaka 10 amaloledwa kupereka mankhwalawa. Kugwiritsa ntchito kumachitika ngati gawo la zovuta mankhwala, sibwino kugwiritsa ntchito monotherapy.

Timapereka kuchotsera kwa owerenga tsamba lathu!

Mosamala, imwani mankhwalawa kwa odwala azaka zopitilira 60. Pakadali pano, chiopsezo chokhala ndi matenda amtima ndi chambiri ndipo kuchita masewera olimbitsa thupi kumawonjezera kukula kwa lactic acidosis.

Kwa mkaka wa msambo muyenera kukana kugwiritsa ntchito Glformin. Ndikulimbikitsidwa kuti musankhe mankhwala ena omwe ali ndi vuto lofananalo.

Kuchita ndi mankhwala ena

Mphamvu ya hypoglycemic imalimbikitsidwa ikaphatikizidwa ndi NSAIDs, sulfonylureas, MAO ndi zoletsa zoletsa za ACE. Ngati mankhwalawa akuyenera kumwa, muyenera kuuza dokotala zaiwo kuti musinthe.

Mukamamwa mankhwalawa, mowa ndi mankhwala omwe amakhala ndi mowa uyenera kutayidwa.

Ndikofunika kupitiriza kutsatira mankhwalawa pakudya osasiyanso machitidwe olimbitsa thupi.

Therapy insulin ndi glyformin ndizogwirizana. Chithandizo choterechi chimaperekedwa kwa mtundu woyamba wa shuga. Mlingo umatha kusiyanasiyana kotero kuti zotsatira za hypoglycemic sizichitika.

Kuphatikiza uku kumagwira othandizira odwala matenda ashuga mellitus, pomwe wodwala amafunikira insulin 200.

Mtundu wachiwiri wa matenda ashuga, insulin siyofunikira. Wodwalayo amamwa mapiritsi mu mlingo womwe adokotala adauza.

Zotsatira zoyipa

Pogwiritsa ntchito mankhwalawa kwa nthawi yayitali pochiza matenda osokoneza bongo omwe amadalira shuga, odwala amazindikira kukoma kwamkamwa. Kukonzekera kwambiri kwa Biguanide kumayambitsa izi. Zimawonetsa kukhumudwa m'matumbo, komwe kumachepetsa kuyamwa kwa matumbo m'matumbo.

Kuchokera m'mimba, mawonekedwe a mseru, kusanza, kugona ndi ululu, kukomoka ndi kusowa kwa chilakolako cha chakudya.

Zotsatira zina zoyipa:

• zotupa pakhungu, urticaria,
• kukula kwa matenda a hypoglycemic mukamamwa mankhwala osavomerezeka,
• pogwiritsa ntchito nthawi yayitali, mayamwidwe a vitamini B12 asokonezeka, hypovitaminosis imayamba,
• Zizindikiro za lactic acidosis.

Zotsatira zoyipa zikachitika, kugwiritsa ntchito mankhwalawa kumatha, amapangana ndi adokotala.

Contraindication

Mankhwalawa saloledwa kugwiritsidwa ntchito panthawi yomwe muli ndi pakati. Pankhaniyi, analogues amalembedwa omwe alibe zotsutsana.

Zoyipa kuti mutenge Gliformin:

• Gawo loyambirira la chikomokere. Mankhwala, matendawa amatchedwa kuti okondweretsa. Amadziwika ndi kusungidwa kwa zowawa komanso mawonekedwe a Reflex.
• Matenda a impso ndi chiwindi. Poyamba, lactic acidosis imayamba.
• Chikuonetseratu musanachite opareshoni komanso patatha masiku awiri atachitidwa opaleshoni.
• Kumwa mapiritsi ndi contraindicated ngati madzi mu thupi, limodzi ndi zina matenda.
• Zakudya za Hypocaloric ndi uchidakwa.
• Kulephera kwa mtima kumapangitsanso kumwa mankhwalawo. Pogwiritsa ntchito metformin, izi zimapangitsa kuti lactic acidosis ipangidwe.

Gliformin imaphatikizidwanso chifukwa chomwera chifukwa cha zakumwa zam'mapapu, kulephera kwa mtima ndi kuphwanya kwamtima. Mndandandandawu umaphatikizapo matenda opatsirana komanso mavuto kupuma.

Bongo

Mankhwala osokoneza bongo mwangozi kapena mwadala akuwonetsa kuti palibe zovuta zoyipa, komabe, mwa odwala okalamba, chiopsezo chimakhala chachikulu.

Kugwiritsa ntchito mankhwalawa mlingo waukulu kumabweretsa kukula kwa lactic acidosis. Pakachitika zinthu zosayembekezereka, mbali ina imatha kufa. Lactic acidosis imapangitsa kuti khungu lisamayende bwino. Chifukwa chake, Glformin siyikulimbikitsidwa kuti mugwiritse ntchito ndi opuwala.

Pankhani ya lactacidemia, wodwalayo amayikidwa kuchipatala, kuzindikira kwake kumamveka bwino ndipo hemodialysis amachitidwa kuti achotse lactates.

Tsiku lililonse kupitilira tsiku lililonse mlingo wa mankhwala, hypoglycemia imayamba. Asayansi ndi madotolo adazindikira izi pamaphunziro a nyama. Mwa anthu, nkhani za hypoglycemia sizinalembedwe.

Pamaso pa contraindication, kupezeka kwa mavuto, mankhwalawa amaloledwa ndi mankhwala ofanana.

• Siofor. Chofunikira chachikulu ndi metformin hydrochloride. Pa nthawi ya chithandizo, siyani kuyamwitsa, imayimitsidwa pakatundu. Tengani 500 mg patsiku, pang'onopang'ono kuwonjezera kuchuluka mpaka mulingo woyenera wabwino kwambiri.
• Metfogamma. Piritsi limodzi lili ndi 500/80 mg ya metformin hydrochloride. Ndikulimbikitsidwa kuti mutenge ndi matenda osokoneza bongo omwe amadalira insulin popanda chizolowezi cha ketoacidosis komanso osagwiritsa ntchito bwino mankhwala. Imwani piritsi 1 patsiku. Kuchulukitsa kwa mankhwalawa kumatheka mpaka mapiritsi 2. Mankhwalawa ndiwotalikirapo.
• Glucophage imagulitsidwa mu mlingo wa 500/50/100 mg. Mankhwalawa amachepetsa thupi, amalepheretsa kukula kwa hyperglycemia ndipo samatsogolera ku hypoglycemia. Akuluakulu amayikidwa 500/50 mg tsiku lililonse. Imwani katatu patsiku. Lekani kumwa munthawi ya matenda, musayike odwala omwe ali ndi matenda a shuga.

Ma Analogi ali ndi mfundo zofananira ndi Glformin. Kukonzekera kumasiyana pokhapokha pazowonjezera, Mlingo ndi mtengo wake.

Glucophage - ma ruble 150-730., Metfogamm - 192-612 ma ruble., Siofor - 231- 381 rubles.

Mankhwala Glyformin amalowa m'malo mwa mankhwalawa pochiza matenda ashuga, monga momwe madokotala amawaganizira kuti ndi othandiza. Komabe, kuwunika kwa wodwala kuli ndi 50% komanso 50% kukhala yosalimbikitsa.

Kuti mumvetsetse ngati mankhwalawo ndi oyenera kwa wodwala kapena akuwonjezera phindu, muyenera kuyeserera momwe mungadziwire.

Glformin anapulumutsa moyo wanga. Maphunziro oyamba anali masiku 20. Panthawi imeneyi, adatsitsa 7 kg. Shuga sakukwera pamlingo wovuta, chilakolako chokhala ndi zolimbitsa thupi.

Yaroslav Manuilov, wazaka 28, ku Moscow:

Kugwiritsa ntchito koyamba kwa mankhwalawa kunatha kulemera, kwa theka la chaka +10 kg. Ndidayamba kugwiritsa ntchito Glucofage, kulemera kumatha, shuga adabwezeretseka.

Glyformin samangochepetsa glucose wa plasma, mankhwalawa amachepetsa mayamwidwe amthupi, amachepetsa thupi, amachititsa kagayidwe kazakudya. Ngati mukufunitsitsa kupeza mankhwala oyenera ndikuganiza zogwiritsa ntchito chida ichi, ndikofunikira kudziwa momwe zingakhudzire thanzi lanu komanso momwe mungamiritsire moyenera.

Matenda a shuga nthawi zonse amayambitsa zovuta zakupha. Mwazi wamagazi ochulukirapo ndi woopsa kwambiri.

Aronova S.M. adafotokoza za chithandizo cha matenda ashuga. Werengani kwathunthu

Kodi Gliformin ali ndi chiyani komanso pang'ono za mtengo wake

Mlingo wa mankhwala Glformin akupezeka m'mitundu itatu:

Chofunikira chachikulu cha glyformin ndi metformin. Ndi kuchuluka kwake komwe kumatsimikizira kuchuluka kwa mapiritsi.

Kuchita bwino pogwiritsa ntchito mankhwalawa kumatheka pokhapokha thupi likupitiliza kupanga zake zake zokha kapena mahomoni akabayidwa. Muyenera kudziwa momwe mungabayire insulin. kukwaniritsa kuchuluka kwa jakisoni wa omn.

Ngati palibe insulini, chithandizo ndi metformin ndichosatheka.

Zotsatira za metformin

1. Metformin imabwezeretsa kapena kukulitsa chidwi cha ma cell ku insulin, mwachitsanzo, mu zotumphukira. Kuphatikiza apo, pali kuwonjezeka kwa ubale wa mahomoni ndi ma receptors, pomwe kuchuluka kwa shuga kumachuluka ndi maselo aubongo, chiwindi, matumbo, ndi khungu.
2. Mankhwalawa amachepetsa kuchuluka kwa shuga ndi chiwindi, ndipo izi sizingakhudze zomwe zili m'magazi a shuga, zomwe ndizofunikira kwambiri mtundu wa 2 shuga. Kwa odwala omwe ali ndi kunenepa kwambiri, kuchepa kwake kosavuta kumachitika, komwe kumakhudza thanzi la wodwalayo.
3. Mankhwala a anorexigenic (kutaya chidwi) ndi chinthu chinanso chabwino cha metformin. Izi zimachitika chifukwa cholumikizana mwachindunji ndi chipinda cham'mimba ndi matumbo, osati zotsatira za malo a ubongo. Ndizachilengedwe kuti kuchepa kwa chakudya kumapangitsa kuchepa kwa zakudya za tsiku ndi tsiku komanso kuchepa kwa thupi kwambiri. Kuchuluka kwa glucose pamenepa kumachepera.
4. Chifukwa cha metformin, pamakhala kudumphadumpha mu glycemia mukatha kudya. Izi zimachitika chifukwa chakuchepa kwa mayamwidwe am'mimba kuchokera m'matumbo, ma cell omwe amalimbikitsa kuchuluka kwa shuga m'thupi.

Kuchokera pazomwe tafotokozazi, zikuwonekeratu kuti metformin ikhoza kufotokozedwa ngati chinthu cha antihyperglycemic.

Ndiye kuti, osalola kuchuluka kwa shuga m'magazi, m'malo mothetsa shuga, awa ndi mapiritsi apamwamba kwambiri ochepetsa shuga.

Zowonjezera za glyformin, kutengera mlingo, zitha kukhala:

Calcium calcium phosphate dihydrate.

• Sorbitol.
• Wowuma wa mbatata.
• Povidone.
• Stearic acid.

Kupanga chipolopolo cha mankhwalawa kumagwiritsidwa ntchito:

Kutengera wopanga, mulingo, kuchuluka kwa mapiritsi omwe ali mgululi, dera lomwe amagulitsa, mtengo wa mankhwalawo umasinthanso. Njira yochiritsira mwezi uliwonse ikuyerekeza pafupifupi ma ruble 200-300.

Masiku ano, glyformin imapangidwa ndi makampani angapo azamankhwala. Mankhwala odziwika kwambiri ku Russia ndi awa:

• GNIISKLS (Russia).
• Akrikhin (Russia).
• Nycomed (Switzerland).

Njira yogwiritsira ntchito ndi pharmacodynamics

Kuchita kwa glyformin kumachitika chifukwa cha metformin, yemwe zotsatira zake ndi:

• kuponderezana kwamatenda a shuga ophatikizidwa ndi chiwindi,
• Kuchepetsa kuchuluka kwa shuga m'matumbo,
• kulimbikitsa kuwonongeka kwa shuga ndi michere ina,
• kuchuluka kwa insulin ndi minofu ndi ma receptors,
• kudya kwakachepa, kuchepa thupi.

Mlingo umodzi ukhoza kukhala 250, 500 ndi 850 mg. ndi 1 g Amatsimikiziridwa ndi endocrinologist payekhapayekha, kutengera zosowa za thupi la matenda ashuga.

Poyamba kumwa mankhwalawa m'masiku atatu oyamba, odwala omwe ali ndi insulin amasonyezedwa kuti amagwiritsa ntchito glyformin kawiri pa 1 g, kapena katatu mu 500 mg. M'tsogolomo, mpaka kumapeto kwa sabata yachiwiri, glyformin imagwiritsidwa ntchito katatu patsiku 1 g.

Kuphatikiza apo, njira ya mankhwalawa imasinthidwa malinga ndi mphamvu ya shuga komanso kugwiritsa ntchito mankhwalawa kwa wodwala winawake. Nthawi zambiri, pambuyo pake chithandizo sichidutsa kawiri mlingo.

Kodi pali kusiyana kotani pakati pa mankhwalawa ndi mawonekedwe ake

Gliformin ali ndi ma fanizo angapo nthawi imodzi, mwa omwe:

Aliyense wa iwo ali ndi mankhwala ofanana, amafunikira njira zomwezi mu shuga mellitus ndi glyformin. Kufanana kwa zochita zawo kumachitika chifukwa cha metformin, yomwe ndi gawo la mankhwala aliwonse. Ndipo kusiyana pakati pawo kumangokhala mtengo komanso mlingo.