Thioctic acid: ndemanga ndi contraindication, malangizo ogwiritsira ntchito

Thioctic acid: malangizo ogwiritsa ntchito ndi kuwunika

Dzina lachi Latin: Thioctic acid

Code ya ATX: A16AX01

Zosakaniza: Thioctic acid (Thioctic acid)

Wopanga: OZON, LLC (Russia)

Kusintha kwamalingaliro ndi chithunzi: 10.24.2018

Mitengo muma pharmacies: kuchokera ku ma ruble 337.

Thioctic acid ndi mankhwala a metabolic.

Kutulutsa mawonekedwe ndi kapangidwe kake

Mlingo wa thioctic acid:

• mapiritsi okhala ndi filimu: ozungulira, biconvex, kuyambira chikasu mpaka chikasu-wobiriwira, mapiritsi a 600 mg ali pachiwopsezo mbali imodzi (zidutswa 10, 20 kapena 30 m'matumba, pabokosi lamakadi 1, 2, 3, 4 , Mapaketi a 5 kapena 10 matuza, 10, 20, 30, 40, 50 kapena 100 zidutswa zilizonse zamatumba azinthu zopangidwa ndi polymer, mu bokosi la makatoni 1 akhoza),
• yang'anani pakukonzekera njira yothetsera kulowetsedwa: madzi owoneka ngati chikasu obiriwira okhala ndi fungo linalake (10 ml pa muloule, 5 ampoules mumtambo wazovala kapena thireyi, mu bokosi la makatoni 1 kapena 2 matuza, kapena thireyi).

Piritsi 1:

• yogwira mankhwala: thioctic acid - 300 kapena 600 mg,
• othandizira: microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, povidone-K25, colloidal silicon dioxide, magnesium stearate,
• chipolopolo: hypromellose, hyprolose, macrogol-4000, titanium dioxide, utoto wa quinoline wachikasu.

The 1 ml ya kuganizira kwambiri pokonza njira yothetsera kulowetsedwa:

• yogwira mankhwala: thioctic acid - 30 mg,
• zothandizira: ethylene diamine, propylene glycol, madzi a jakisoni.

Mankhwala

Thioctic kapena α-lipoic acid imatha kumanga ma radicals aulere. Kapangidwe kake m'thupi kumachitika nthawi ya oxidative decarboxylation ya α-keto acid. Thioctic acid imakhudzidwa ndi oxidative decarboxylation ya pyruvic acid, komanso α-keto acid, ngati coenzyme ya multienzyme mitochondrial complexes. Mukuchita kwake kwachilengedwe, ili pafupi ndi mavitamini a B.

Mankhwala amathandizanso trophism ya neurons, amachepetsa kuchuluka kwa shuga m'magazi, amachepetsa kuchuluka kwa glycogen m'chiwindi, amachepetsa kukana kwa insulin, amathandizanso kukonza chiwindi, komanso amatenga nawo gawo potsatira kayendedwe ka chakudya ndi lipid metabolism.

Pharmacokinetics

Ikaperekedwa, thioctic acid imatengedwa mwachangu komanso kwathunthu. Mu mphindi 40-60, kuphatikiza kwakukulu m'thupi kumakwaniritsidwa. Bioavailability ndi 30%.

Pambuyo pa utsogoleri wa mankhwalawa muyezo wa 600 mg kwa mphindi 30, kuchuluka kwake kwa plasma (20 μg / ml) kumatheka.

Kagayidwe kachakudya mankhwala amapezeka mu chiwindi, ndi makutidwe ndi okosijeni a mbali unyolo ndi conjugation. Mankhwala ali ndi mphamvu ya gawo loyambalo kudzera mu chiwindi.

Imafufutidwa ndi impso (80-90%), theka la moyo ndi mphindi 20-50. Kugawa voliyumu - pafupifupi 450 m / kg. Chilolezo chonse cha plasma ndi 10-15 ml / min.

Contraindication

• lactose tsankho, kufupika kwa lactase, shuga-galactose malabsorption (mapiritsi),
• Mimba ndi kuyamwa
• wazaka 18
• kuchuluka kwa magawo a mankhwalawa.

Chenjezo liyenera kuchitika pakukhazikitsa thioctic acid kwa anthu azaka zopitilira 75.

Malangizo a Thioctic acid: njira ndi mlingo

Mankhwalawa monga mapiritsi amatengedwa mokwanira, osapwanya kapena kutafuna, mphindi 30 musanadye kadzutsa, ndi madzi ambiri.

Mlingo woyenera wa Thioctic acid ndi 600 mg kamodzi patsiku.

Kulandila kwa piritsi mawonekedwe a mankhwalawa imayamba pambuyo pa mapangidwe a makolo pakadutsa masabata awiri. Njira yayitali kwambiri yotsatirira mapiritsiwa ndi milungu 12. Kuchiza kwakutali ndi kotheka monga kuuzidwa ndi dokotala.

Tsatirani njira yothetsera kulowetsedwa

Njira yothetsera vutoli imathandizira kukoka pang'onopang'ono.

Mlingo wovomerezeka wa Thioctic acid ndi 600 mg (2 ampoules) patsiku.

Njira yothetsera: wonongerani zomwe zili mumapulogalamu awiri mu 250 ml ya 0,9% sodium kolorayidi. M'pofunika kukonzekera yankho musanalowe kulowetsedwa. Kukonzekera kwakonzedweraku kuyenera kutetezedwa ku kuwala, momwemo kumatha kusungidwa mpaka maola 6.

Zotsatira zake zimayendetsedwa kudzera mu mtsempha wa magazi pang'onopang'ono (osachepera mphindi 30). Njira yakugwiritsira ntchito mankhwalawa ndi masabata 2-4, ndiye kuti muyenera kupita ku mapiritsi a Thioctic acid.

Zotsatira zoyipa

• GIT (matumbo am'mimba): nseru, kusanza, kutsegula m'mimba, kupweteka kwam'mimba, kupweteka kwam'mimba,
• chitetezo chamthupi: ziwopsezo zamkati (zotupa, kuyabwa, urticaria), zina zonse zoyipa, mpaka kugwedezeka kwa anaphylactic,
• dongosolo lamanjenje: kusintha kukoma
• kagayidwe ndi zakudya: hypoglycemia (Zizindikiro zake: kutuluka thukuta, chizungulire, kupweteka kwa mutu, kusokonezeka kowoneka).

Bongo

Zizindikiro za bongo wa thioctic acid: nseru, kusanza, kupweteka mutu. Mukamwa 10 mpaka 40 g ya mankhwalawa, zotsatirazi za kuledzera ndizotheka: kukomoka kwakukulu, hypoglycemic chikomokere, matenda osokoneza bongo omwe amatsogolera ku lactic acidosis, matenda okhetsa magazi kwambiri, mpaka imfa, mafupa am'mimba a necrosis, DIC, hemolysis , Kulephera kwamitundu yambiri, kuponderezana kwa mafupa.

Palibe mankhwala enieni. Chithandizo cha Syndrome. Pankhani ya bongo wambiri, kuchipatala kwadzidzidzi kumasonyezedwa. Chithandizo: chapamimba cha m'mimba, kudya kaboni yokhazikitsidwa, anticonvulsant, kukonza zofunikira za thupi.

Malangizo apadera

Mukamamwa mankhwala a Thioctic acid, muyenera kupewa kumwa mowa.

Odwala omwe ali ndi matenda ashuga amafunika kuwunika pafupipafupi kuchuluka kwa shuga m'magazi, makamaka kumayambiriro kwa kugwiritsa ntchito mankhwalawa. Popewa hypoglycemia, kusintha kwa insulin kapena mkamwa wa hypoglycemic kungafunike. Zizindikiro za hypoglycemia zikaonekera, asidi wa thioctic ayenera kusiyidwa nthawi yomweyo.

Ndikupangiridwanso kuti musiye kugwiritsa ntchito mankhwalawa ngati mungakumane ndi vuto la hypersensitivity, monga kuyabwa ndi malaise.

Kuyanjana kwa mankhwala

Kutalikirana kwa maola osachepera awiri kuyenera kuchitika mukamamwa mankhwala a thioctic ndikukonzekera zomwe zimakhala ndi zitsulo zamkaka, komanso zinthu monga mkaka.

Mankhwala ofunikira kwambiri a thioctic acid ndi mankhwala / zinthu zotsatirazi:

• cisplatin: mphamvu yake yafupika,
• glucocorticosteroids: awo odana ndi kutupa amakhala
• Mowa ndi metabolites: kuchepetsa mphamvu ya asidi wa thioctic,
• insulin ndi pakamwa hypoglycemic wothandizila: zake zimatheka.

Zomwe zimapangidwira pakukonzekera njira yothetsera kulowetsedwa sizigwirizana ndi mayankho a dextrose (glucose), fructose, Ringer, komanso ndi mayankho omwe amachitika ndi disulfide kapena SH-magulu.

Thioctic Acid Ndemanga

Ndemanga zam'magawo atatu muukonde ndizabwino. Madokotala amayamikirira kwambiri mankhwala ake monga neuroprotector ndi antioxidant wachilengedwe, ndipo amalimbikitsa kugwiritsa ntchito pafupipafupi kwa odwala omwe ali ndi matenda osokoneza bongo a polyellurus ndi polyneuropathies. Odwala ambiri, makamaka azimayi, amamwa mankhwalawa kuti achepetse thupi, koma malingaliro amagawidwa pazoyenera kwa thioctic acid kuti achepetse kunenepa kwambiri. Mtengo wokwera wa mankhwala umadziwikanso.

Kodi mankhwalawa amagwiritsidwa ntchito nthawi ziti?

Thioctacid kapena lipoic acid ndi coenzyme wa oxidative decarboxylation wa pyruvic acid ndi mitundu yambiri ya alpha-keto. Izi zimatenga mbali mu matenda a metabolic ambiri omwe amachitika mthupi, komanso kagayidwe ka cholesterol.

Mankhwala amaperekedwa ngati ufa wa kuwala pang'ono wachikasu, wokhala ndi zowawa pambuyo pake. Dziwani kuti zinthu sizisungunuka m'madzi, koma mu Mowa. Pokonzekera mankhwala azachipatala, mawonekedwe osungunuka a ufa wotere amagwiritsidwa ntchito - mchere wa trometamol.

Pharmacology yamakono imapanga kukonzekera kwa thioctic acid mu mawonekedwe a mapiritsi ndi njira zothetsera jakisoni (intramuscularly and intrarally).

Malangizo omwe amagwiritsidwa ntchito popangira mankhwalawa amasiyanitsa zotsatirazi zikuluzikulu za kutenga thioctic acid:

• ndi kukula kwa matenda a shuga a mtundu wachiwiri, komanso matenda ashuga a polyneuropathy,
• anthu omwe ali ndi chidakwa cha polyneuropathy,
• Mankhwala osokoneza bongo othandizira matenda a chiwindi, monga ziwonetsero za chiwindi, mafuta osintha a ziwalo, chiwindi, komanso mitundu ina ya poizoni.
• amachita hyperlipidemia.

Chifukwa chiyani ndimakonzedwe a thioctic acid amagwiritsidwa ntchito? Popeza mankhwalawa ndi antioxidant ndipo amaphatikizidwa ndi gulu lokonzekera mavitamini, nthawi zambiri amagwiritsidwa ntchito kutulutsa njira zama metabolic ndikuchepetsa thupi. Kuphatikiza apo, chida choterechi chimagwiritsidwa ntchito mwachangu ndi osewera kuthana ndi ma radicals omasuka ndikuchepetsa mulingo wa oxidation mukatha kuchita masewera olimbitsa thupi.

Thioctic acid, yomwe amawunikira ikuwonetsa kuti imathandizira komanso kupititsa patsogolo shuga wa m'matumbo, imakhala ndi phindu pakulimbikitsa kuteteza kwa glycogen.

Ndiye chifukwa chake, nthawi zambiri amagwiritsidwa ntchito ngati chowotchera mafuta.

Zotsatira za pharmacological

Ntchito yofunikira kwambiri m'thupi la munthu ndi kuphatikiza modabwitsa njira zosiyanasiyana zomwe zimayamba kuyambira nthawi yomwe mayi ali ndi pakati ndipo osasiya sekondi yamoyo wonse. Nthawi zina zimawoneka ngati zosamveka. Mwachitsanzo, zinthu zofunika kwambiri pakapangidwe kazachilengedwe - mapuloteni - amafunikira mankhwala okhala ndi mapuloteni, otchedwa cofactor, kuti agwire ntchito moyenera. Ndi zinthu izi zomwe lipoic acid, kapena, momwe amatchedwanso, thioctic acid, ndiyayo. Ndi gawo lofunikira la ma enzymatic ma protein omwe amagwira ntchito mthupi la munthu. Chifukwa chake, shuga akawonongeka, chinthu chotsiriza chimakhala mchere wa pyruvic acid - ma pyruvates. Ndi lipoic acid yomwe imakhudzidwa ndi njirayi. Momwe zimakhudzira thupi la munthu, ndizofanana ndi mavitamini a B - zimatenganso kagayidwe ka lipid ndi carbohydrate, zimawonjezera zomwe zili m'magazi a chiwindi komanso zimathandizira kuchepetsa kuchuluka kwa shuga m'magazi.

Chifukwa cha kuthekera kwake kukonza kagayidwe ka cholesterol ndi ntchito ya chiwindi, lipoic acid imachepetsa mphamvu ya zovuta za poogenic ya onse amkati komanso zochokera kunja. Mwa njira, mankhwalawa ndi antioxidant yogwira, yomwe imatengera mphamvu yake yomanga ma radicals aulere.

Malinga ndi maphunziro osiyanasiyana, thioctic acid ali ndi hepatoprotective, hypolipidemic, hypocholesterolemic ndi hypoglycemic.

Zophatikiza zamafuta ngati izi za Vitamini zimagwiritsidwa ntchito pochita zachipatala kupereka mankhwala osokoneza bongo, kuphatikizapo zinthu zina, magawo ena a zochita za thupi. Ndipo kuphatikizidwa kwa lipoic acid mu jakisoni njira kumachepetsa kukula kwa zovuta zamankhwala.

Kodi mitundu ya mitundu ndi iti?

Kwa mankhwala "Lipoic acid", mlingo wa mankhwalawa umaganizira zofunikira zothandizira, komanso momwe zimaperekedwera thupi. Chifukwa chake, mankhwalawa angagulidwe muma pharmacies m'mitundu iwiri - mu mapiritsi ndi mawonekedwe a yankho mu jekeseni ma ampoules. Kutengera ndi omwe kampani yopanga mankhwala amapanga mankhwalawa, mapiritsi kapena makapisozi amatha kugulidwa ndi zomwe zili ndi 12,5 mpaka 600 mg wa yogwira mu 1 unit. Mapiritsi amapezeka mu zokutira zapadera, zomwe nthawi zambiri zimakhala ndi mtundu wachikaso. Mankhwalawa amapezeka m'matumba ndi m'mapaketi okhala ndi mapiritsi 10, 50 kapena 100. Koma mu ampoules, mankhwalawa amapezeka mwa mawonekedwe a 3%. Thioctic acid ndi gawo limodzi la mankhwala ambiri okhala ndi zinthu zambiri komanso zakudya zamagulu ena.

Kodi kugwiritsa ntchito mankhwalawo kukuwoneka kuti?

Chimodzi mwazinthu zokhala ndi mavitamini ofunikira m'thupi la munthu ndi lipoic acid. Zizindikiro zogwiritsidwa ntchito zimaganizira momwe zimagwirira ntchito ngati gawo limodzi la intracellular, ndizofunikira m'njira zambiri. Chifukwa chake, lipoic acid, kuvulaza ndi maubwino omwe nthawi zina amayambitsa mikangano pagulu laumoyo, ali ndi zisonyezo zina zogwiritsidwa ntchito pochiza matenda kapena zikhalidwe monga:

• coronary atherosulinosis,
• tizilombo toyambitsa matenda a chiwindi (ndi jaundice),
• matenda a chiwindi mu gawo yogwira,
• dyslipidemia - kuphwanya mafuta kagayidwe, kamene kamaphatikizanso kusintha kwa lipids ndi lipoprotein yamagazi,
• hepatic dystrophy (mafuta),
• kuledzera ndi mankhwala, zitsulo zolemera, kaboni, kaboni tetrachloride, bowa (kuphatikiza mafuta akhungu),
• pachimake chiwindi kulephera
• chifuwa chachikulu pa zakumwa zoledzeretsa,
• matenda ashuga polyneuritis,
• zakumwa zoledzeretsa,
• aakulu cholecystopancreatitis,
• hepatic cirrhosis.

Gawo lalikulu la ntchito ya mankhwala a Lipoic Acid ndi chithandizo cha uchidakwa, poizoni ndi kuledzera, mankhwalawa a hepatic pathologies, dongosolo lamanjenje, komanso matenda a shuga. Komanso, mankhwalawa nthawi zambiri amagwiritsidwa ntchito pochiza khansa ndi cholinga chothandizira matenda.

Kodi pali zotsutsana ndi ntchito?

Popereka mankhwala, odwala nthawi zambiri amafunsa madokotala - mankhwala a lipoic acid ndi ati? Yankho la funsoli limatha kukhala lalitali kwambiri, chifukwa thioctic acid amatenga mbali pama cellular omwe amayang'aniridwa ndi metabolism ya zinthu zosiyanasiyana - lipids, cholesterol, glycogen. Amachita nawo zodzitchinjiriza motsutsana ndi ma free radicals komanso oxidation wama cell minofu. Kwa mankhwala "Lipoic acid", malangizo omwe angagwiritsidwe ntchito samangowonetsa mavuto omwe amathandizira kuthetsa, komanso contraindication kuti agwiritse ntchito. Ndipo ndi awa:

• Hypersensitivity
• mbiri yakusokonekera kwa mankhwalawa.
• mimba
• Nthawi yodyetsa mwana mkaka wamawere.

Mankhwalawa sanalembedwe pochiza ana osaposa zaka 16 chifukwa cha kusowa kwa mayesero azachipatala mu mtsempha uwu.

Kodi pali zovuta zina?

Chimodzi mwazinthu zofunika kwambiri pa cellular ndi lipoic acid. Chifukwa chiyani chimafunikira m'maselo? Kuchita zingapo zamagetsi ndi zamagetsi zimakhudza njira ya metabolic, komanso kuchepetsa zovuta za oxidation. Koma ngakhale mutapindula ndi mankhwalawa, kumwa mankhwala okhala ndi thioctic acid kulibe nzeru, osati cholinga cha katswiri, ndizosatheka. Kuphatikiza apo, mankhwalawa amatha kuyambitsa zotsatirazi:

• thupi lawo siligwirizana
• kupweteka kwa epigastric
• achina,
• kutsegula m'mimba
• diplopia (masomphenya apawiri),
• kuvutika kupuma
• zotupa pakhungu (totupa ndi kuyabwa, urticaria),
• magazi (chifukwa cha matenda a thrombocytosis),
• migraine
• petechiae (zikhomo zotupa),
• kuchuluka kwazovuta zamkati,
• kusanza
• kukokana
• nseru

Momwe mungamwe mankhwala osokoneza bongo a thioctic acid?

Kwa mankhwala "Lipoic acid", malangizo omwe angagwiritsidwe ntchito amafotokozera zoyambira zamankhwala, kutengera mlingo woyambirira wa gawo la mankhwalawa. Mapiritsiwo sanatafunike kapena kuwaphwanya, kuwatenga mkati mwa ola limodzi asanadye.Mankhwalawa amatchulidwa mpaka katatu patsiku, kuchuluka kwa mankhwalawa komanso kuchuluka kwa mankhwalawa amatsimikiziridwa ndi adokotala mogwirizana ndi kufunika kwa mankhwalawo. Mlingo wovomerezeka wa tsiku ndi tsiku wa mankhwala ndi 600 mg ya yogwira ntchito.

Zochizira matenda amchiwindi, kukonzekera kwa mankhwala a lipoic ayenera kutengedwa kanayi pa tsiku kuchuluka kwa 50 mg yogwira ntchito panthawi. Njira ya mankhwalawa iyenera kukhala mwezi umodzi. Itha kubwerezedwa pambuyo pa nthawi yomwe adokotala awonetsa.

Mitsempha makonzedwe a mankhwala zotchulidwa mu milungu yoyamba ya matenda a matenda pachimake ndi mitundu mitundu. Pambuyo pa nthawi imeneyi, wodwalayo amatha kusamutsidwira piritsi la mankhwala a lipoic acid. Mlingo uyenera kukhala womwewo pamitundu yonse ya Mlingo - jakisoni wamkati uli ndi 300 mpaka 600 mg yogwira ntchito patsiku.

Momwe mungagule mankhwala ndi momwe mungasungire?

Monga momwe malangizo a mankhwalawa amagwiritsidwira ntchito, mankhwala a lipoic acid omwe amagulitsidwa amaperekedwa ndi mankhwala. Kugwiritsa ntchito kwake osakambirana ndi dokotala yemwe akulandira sikulimbikitsidwa, chifukwa mankhwalawa ali ndi zochita zambiri zam'magazi, kugwiritsa ntchito mankhwala osokoneza bongo kuyenera kuganiziranso kuyanjana ndi mankhwala ena omwe wodwala akutenga.

Mankhwala omwe agulidwa mu mawonekedwe a piritsi komanso monga yankho la jakisoni amasungidwa pamtunda wofunda popanda kulowa kwa dzuwa.

Zabwino kapena zoyipa limodzi?

Chomwe chimalimbikitsanso kuchitira mankhwala omwe mumadziphatikiza ndi mankhwala osiyanasiyana, kuphatikizapo mankhwala a "Lipoic acid", mtengo wake ndi kuwunika. Poganiza kuti zopindulitsa zachilengedwe zokha zomwe zingapezeke kuchokera ku chinthu chachilengedwe chokhala ndi mavitamini, odwala ambiri amaiwala kuti palinso zomwe zimadziwika kuti ndizotsatira zamankhwala, zomwe ziyenera kukumbukiridwa. Mwachitsanzo, kuphatikiza kwa glucocorticosteroids ndi mankhwala okhala ndi thioctic acid kumadzaza ndi zochita zowonjezereka zamahomoni a adrenal, zomwe zimayambitsa zotsatira zoyipa zambiri.

Popeza lipoic acid imamanga zinthu zambiri mthupi, siziyenera kuphatikizidwa ndi kugwiritsa ntchito mankhwala okhala ndi zinthu monga magnesium, calcium, potaziyamu, ndi chitsulo. Kuchiza ndi mankhwalawa kuyenera kugawidwa pakanthawi - kupuma kwa maola osachepera 2-4 ndi njira yabwino kwambiri yothanirana ndi mankhwalawa.

Kuchiza ndi ma tinctures okhala ndi mowa kumathandizidwanso mosiyana ndi lipoic acid, chifukwa Mowa amachepetsa ntchito yake.

Kodi ndizotheka kuti muchepetse thupi pogwiritsa ntchito thioctic acid?

Anthu ambiri amakhulupirira kuti imodzi mwazinthu zothandiza komanso zotetezeka zofunika kusintha kulemera ndi mawonekedwe ndi lipoic acid kuti muchepe. Momwe mungamwe mankhwalawa kuti muchotse mafuta owonjezera m'thupi? Ili siliri vuto, popeza kuti popanda kuchita zolimbitsa thupi komanso kusintha zakudya, palibe mankhwala omwe angakwanitse kuwonda. Ngati mungayang'anenso malingaliro anu pa maphunziro akuthupi komanso kudya zakudya zoyenera, ndiye kuti thandizo la lipoic acid pakuchepetsa thupi lidzadziwika kwambiri. Mutha kumwa mankhwalawo mosiyanasiyana:

• theka la ola musanadye kadzutsa kapena theka la ola litatha,
• theka la ola asanadye,
• atatha masewera olimbikira.

Kulingalira kwamtunduwu kumakhudzana ndi kugwiritsa ntchito lipoic acid pakukonzekera 25-50 mg patsiku. Zithandiza kagayidwe ka mafuta ndi shuga, komanso kuchotsa cholesterol yosafunikira m'thupi.

Kukongola ndi thioctic acid

Amayi ambiri amagwiritsa ntchito mankhwalawa "Lipoic acid" pankhope, zomwe zimathandiza kuti khungu likhale loyera kwambiri. Kugwiritsa ntchito mankhwala okhala ndi thioctic acid kumatha kusintha mtundu wa moisturizer wokhazikika kapena zonona zabwino. Mwachitsanzo, madontho angapo a jakisoni owonjezeredwa ku kirimu kapena mafuta odzola omwe mayi amagwiritsa ntchito tsiku lililonse amapangitsa kuti azitha kwambiri polimbana ndi zovuta, kuwonongeka kwa khungu, komanso kuwonongeka kwa khungu.

Ndi matenda ashuga

Chimodzi mwazinthu zofunika kwambiri pantchito ya kagayidwe ndi kagayidwe kazigawo, motero, insulin, ndi lipoic acid. Mtundu woyamba wa 1 komanso wa shuga wa 2, chinthu ichi chimathandiza kupewa mavuto akulu omwe amakhudzana ndi oxidation, zomwe zikutanthauza kuwononga maselo a minofu. Kafukufuku awonetsa kuti njira za oxidative zimayendetsedwa ndikuwonjezereka kwa shuga wamagazi, ndipo zilibe kanthu pazifukwa zotere. Lipoic acid imagwira ntchito ngati antioxidant, yomwe imachepetsa kwambiri zotsatira zoyipa za shuga m'magazi. Kufufuza m'derali kukupitirirabe, chifukwa chake mankhwala omwe ali ndi matenda a shuga a shuga amayenera kumwedwa pokhapokha ngati dokotala amupeza powunika ziwerengero zamagazi ndi momwe wodwalayo alili.

Amati chiyani za mankhwalawa?

Chomwe chimagwiritsa ntchito mankhwala ambiri omwe ali ndi zochita zazachilengedwe ndi lipoic acid. Mavuto ndi zopindulitsa za chinthuchi ndizomwe zimayambitsa mikangano pafupipafupi pakati pa akatswiri, pakati pa odwala. Ambiri amaganiza kuti mankhwalawa ndi tsogolo lamankhwala, omwe thandizo lawo popereka matenda osiyanasiyana limatsimikiziridwa ndi machitidwe. Koma anthu ambiri amaganiza kuti mankhwalawa ali ndi mphamvu yotchedwa placebo yokha ndipo sanyamula katundu aliyense wogwira ntchito. Komabe, ndemanga zambiri pamankhwala "Lipoic acid" omwe ali ndi lingaliro labwino komanso logwirizana. Odwala omwe amamwa mankhwalawa ndi maphunzirowa amati atatha kulandira chithandizo, amayamba kulakalaka kwambiri. Ambiri amadziwa kuwongolera - mawonekedwe ake adatsuka, ziphuphu zimatha. Komanso, odwala amawona kuwonjezeka kwakukulu pakuwerengera magazi - kuchepa kwa shuga ndi cholesterol atatha kumwa mankhwala. Ambiri amati lepic acid nthawi zambiri amagwiritsidwa ntchito pakuchepetsa thupi. Momwe mungatengere chida chotere kuti mutaye mapaundi owonjezera ndi nkhani yapamwamba kwa anthu ambiri. Koma aliyense amene amamwa mankhwalawa kuti achepetse thupi amanenanso kuti sizingachitike popanda kusintha kadyedwe ndi moyo wake.

Mankhwala ofanana

Zamoyo zofunika kupezeka mthupi la munthu zimathandiza polimbana ndi matenda ambiri, komanso zinthu zam'magazi zomwe zimakhudza thanzi. Mwachitsanzo, lipoic acid. Mavulidwe ndi phindu la mankhwalawa, ngakhale amayambitsa mikangano, komabe othandizira odwala ambiri, izi zimagwira ntchito yayikulu. Mankhwala omwe ali ndi dzina lomweli ali ndi ma analogues ambiri, omwe amaphatikizapo lipoic acid. Mwachitsanzo, Oktolipen, Espa-Lipon, Tiolepta, Berlition 300. Itha kupezekanso pazithandizo zamitundu mitundu - "Alphabet - Shuga", "Complivit Radiance."

Wodwala aliyense yemwe akufuna kusintha momwe alili ndi mankhwala kapena zakudya zina zogwirizana ndi zakudya, kuphatikiza mankhwala okonzekera a lepic, ayenera kufunsa katswiri wofotokoza za chithandizo chotere, komanso pazovuta zilizonse.

Ndemanga za madotolo za thioctic acid

Mankhwalawa ndi osangalatsa malinga ndi ake omwe amatchulidwa kuti antioxidant katundu. Ndimagwiritsa ntchito umuna kwa odwala omwe ali ndi vuto logontha la abambo kuti athane ndi oxidative nkhawa, omwe maoror amatenga nawo chidwi kwambiri. Chizindikiro cha matenda a thioctic acid ndi chinthu chimodzi - matenda ashuga polyneuropathy, koma malangizowo akunenanso momveka bwino kuti "ichi sichifukwa chofooketsa kufunika kwa matenda a thioctic acid."

Kugwiritsa ntchito nthawi yayitali, kumatha kusintha zomverera, kutsitsa chidwi, thrombocytopenia ndikotheka.

Kupanga mankhwala a antioxidant ndikofunikira kwachipatala pofuna kuchiza matenda ambiri a urogenital sphere.

Neuroprotector wapadziko lonse wokhala ndi antioxidant katundu, wogwiritsidwa ntchito nthawi zonse ndi odwala omwe ali ndi matenda osokoneza bongo, komanso odwala polyneuropathies, ndiye kuti ali ndi chifukwa.

Mtengo uzikhala wotsika pang'ono.

Pazonse, mankhwala abwino okhala ndi antioxidant katundu. Ndikupangira kugwiritsa ntchito kuchipatala.

Ndimagwiritsa ntchito njira zovuta za odwala omwe ali ndi matenda ashuga phokoso, mawonekedwe a neuro-ischemic. Kugwiritsa ntchito pafupipafupi kumabweretsa zotsatira zabwino.

Odwala ena sakudziwitsidwa za chithandizo chamankhwala awa.

Odwala omwe ali ndi matenda ashuga ayenera kulandira chithandizo chochepa kwambiri ndi mankhwalawa kawiri pachaka.

Kulekerera kwabwino kwambiri ndi zotsatira zake mwachangu mukagwiritsidwa ntchito kudzera m'mitsempha.

Katunduyo ndi wosakhazikika, amawola msanga mothandizidwa ndi kuwala, chifukwa chake pakaperekedwa kudzera m'mitsempha, ndikofunikira kukulunga botolo la yankho mu foil.

Lipoic acid (thiogamma, thioctacid, zipatso, kukonzekera kwa octolipen) amagwiritsidwa ntchito popewa kuthana ndi matenda a shuga mellitus, makamaka matenda ashuga polyneuropathy. Ndi ma polyneuropathies ena (mowa, poizoni) amakhalanso ndi zotsatira zabwino.

Ndemanga za Odwala pa Thioctic Acid

Mankhwalawa adandiwuza kuti ndichepetse kulemera kwa thupi, adandiuza kuti ndiwonjezere 300 mg katatu patsiku, kwa miyezi itatu nditagwiritsa ntchito mankhwalawa khungu langa limatha, masiku anga ovuta adayamba kuvuta, tsitsi langa lidasiya, koma kulemera kwanga sikunasunthe, Izi ndi izi ngakhale ndizotsatira CBJU. Kupititsa patsogolo kolonjezedwa kwa kagayidwe kazakudya, sizinachitike. Komanso, mukamagwiritsa ntchito mankhwalawa, mkodzo umakhala ndi fungo linalake, mwina ammonia, kapena sizikudziwika bwino. Mankhwala anakhumudwitsidwa.

Antioxidant wamkulu. Yotsika mtengo komanso yothandiza. Mutha kutenga nthawi yayitali popanda zotsatira zoyipa.

Ndinaikidwa thioctic acid ndipo ndimamwa piritsi 1 limodzi patsiku kwa miyezi iwiri. Ndili ndi mphamvu yotsatila ya mankhwalawa ndipo malingaliro anga okoma adatha.

Thioctic acid kapena dzina lina ndi lipoic acid. Ndidachita maphunziro a 2 a mankhwala ndi mankhwalawa - woyamba maphunziro a miyezi iwiri mchaka, ndiye pambuyo miyezi iwiri kachiwiri maphunziro awiri miyezi. Pambuyo pa maphunziro oyamba, kupirira kwa thupi kumakhala bwino (mwachitsanzo, maphunziro asanachitike, ndikanatha kuchita ma squats 10 osapumira, pambuyo pa maphunziro a 1 kale 20-25). Kulakalaka kunachepa pang'ono ndipo zotsatira zake, kuchepa kwa thupi kuchoka pa 120 mpaka 110 makilogalamu m'miyezi itatu. Nkhopeyo inayamba kupinki, mthunzi wa ashen unatha. Ndinkamwa mapiritsi 2 nthawi 4 patsiku pa ndandanda pafupipafupi (kuyambira 8 koloko maola 4 aliwonse).

Kufotokozera kwapfupi

Thioctic acid ndi kagayidwe kazinthu kamene kamayendetsa kagayidwe kazakudya ndi mafuta. Malangizo ogwiritsira ntchito mankhwalawa amapereka chidziwitso chimodzi - matenda ashuga polyneuropathy. Komabe, ichi sichiri chifukwa chonyozera kufunikira kwa matenda a thioctic acid machitidwe azachipatala. Ma antioxidant am'mbuyomu amatha kukhala ndi mphamvu yomanga zida zotsalira zaulere. Thioctic acid imagwira nawo ntchito ma cell metabolism, imagwira ntchito ya coenzyme m'njira zosiyanasiyana zomwe zimateteza maselo kuti asagwiritsidwe ntchito mwaulere. Thioctic acid imapangitsa zochita za insulini, zomwe zimagwirizanitsidwa ndi kuyambitsa kwa kugwiritsira ntchito shuga.

Matenda oyambitsidwa ndi vuto la endocrine-metabolic akhala ali m'malo aza madokotala kwazaka zopitilira zana. Kumapeto kwa zaka za ma 80 za zana lomaliza, lingaliro la "insulinelane syndrome" linayambitsidwa koyamba mu mankhwala, komwe, kuphatikiza insulin, kulekerera shuga, kuchuluka kwa cholesterol "yoyipa", kutsika kwa cholesterol "yabwino", komanso kunenepa kwambiri ndi matenda oopsa. Matenda a insulin kukana ali ndi dzina lofanana "metabolic syndrome". Mosiyana ndi izi, akatswiri azachipatala adapanga njira zoyambira za kagayidwe kachakudya koyeserera maselo, zomwe zimapangitsa ntchito zake kuti zizigwira bwino ntchito, zomwe zimathandiza kuti thupi lonse lizigwira ntchito. Metabolic therapy imakhudzana ndi mankhwala a mahomoni, kukhalabe ndi mtundu wocheperako wa cholera ndi ergocalciferol (mavitamini a gulu D), komanso chithandizo chofunikira ndi mafuta acids, kuphatikizapo alpha-lipoic kapena thioctic. Pankhaniyi, ndikulakwa kwambiri kuganizira za antioxidant mankhwala omwe ali ndi thioctic acid pokhapokha pochiza matenda a shuga.

Monga mukuwonera, mankhwalawa ndi gawo lofunikira kwambiri pa metabolic therapy. Poyamba, thioctic acid amatchedwa "Vitamini N", kutanthauza kufunika kwake kwamanjenje. Komabe, momwe amapangidwira, mankhwala awa si mavitamini. Ngati simunayesere kulowa "m'nkhalango" ya biochemical pofotokoza za ma dehydrogenase maofesi ndi kayendedwe ka Krebs, ziyenera kudziwika kuti katundu wa antioxidant wa thioctic acid, komanso kutenga nawo gawo pokonzanso ma antioxidants ena, mwachitsanzo, vitamini E, coenzyme Q10 ndi glutathione. Kuphatikiza apo: thioctic acid ndiwothandiza kwambiri kuposa ma antioxidants onse, ndipo ndizomvetsa chisoni kuti anthu sanazindikire phindu la mankhwala ake komanso kuchepera kwa malingaliro ake osagwiritsidwa ntchito, omwe ali ndi malire, monga tafotokozera kale, okhawo omwe ali ndi vuto la matenda ashuga. Neuropathy ndikusintha kwa minyewa yoipa, komwe kumayambitsa kusokonezeka kwamitsempha, zotumphukira komanso zotupa komanso kuperewera kwa ziwalo zosiyanasiyana. Tizilombo tonse ta m'mitsempha timakhudzidwa, kuphatikizapo ndi ma receptor. The pathogenesis ya neuropathy nthawi zonse imagwirizanitsidwa ndi njira ziwiri: kuphwanya mphamvu kagayidwe kazinthu ndi kupsinjika kwa oxidative. Popeza "tropism" yotsirizira minofu yamanjenje, ntchito yachipatala imangophatikizapo kuzindikira kwathunthu kwa zizindikiro za neuropathy, komanso chithandizo chake chogwira ntchito ndi thioctic acid. Popeza chithandizo (makamaka, ngakhale kupewa) kwa neuropathy ndichothandiza kwambiri ngakhale isanayambike zizindikiro za matendawa, ndikofunikira kuyamba kumwa mankhwala a thioctic posachedwa.

Thioctic acid imapezeka m'mapiritsi. Mlingo umodzi wa mankhwalawa ndi 600 mg. Popeza synergism ya thioctic acid ku insulin, ndi munthawi yomweyo kugwiritsa ntchito mankhwalawa, chiwopsezo cha hypoglycemic cha insulin ndi piritsi hypoglycemic chingadziwike.