Humalog - malangizo ogwiritsira ntchito

Matenda a shuga ndi matenda ofala kwambiri masiku ano. Zomwe zimayambitsa matendawa zimatha kukhala zosiyana kwambiri, koma chibadwa ndichofunikira kwambiri pamenepa. 10-15% ya anthu onse odwala matenda ashuga ndi mtundu 1 shuga, mankhwalawa amafunika kudya insulin m'njira jakisoni. Ndizofunikira kudziwa kuti shuga 1 yamtunduwu imadziwika ndi kukula kwa zizindikiro zazikulu muubwana komanso unyamata, komanso kukula msanga kwa zovuta zomwe zimayambitsa kusokonezeka kwa magwiridwe antchito amunthu kapena thupi lonse. Chifukwa chake, ndikofunikira kuti muyambe kulandira chithandizo munthawi yake.

Kuchita insulin m'malo mwake, mankhwala monga Humalog amagwiritsidwa ntchito. Malangizo ogwiritsira ntchito adzakambidwanso pambuyo pake, ndipo tidzadziwanso kuwunika kwa odwala pazabwino komanso zabwino za mankhwalawa.

Mawonekedwe ndi kapangidwe ka mankhwala

Chofunikira chachikulu pa mankhwalawa ndi insulin lispro. Zowonjezera - glycerol, metacresol, zinc oxide, sodium hydrogen phosphate heptahydrate, hydrochloric acid, madzi.

Humalog insulin ndi yobwerezabwereza, yosinthika, analogue ya insulin ya anthu. Kusiyanako ndikusinthasintha kwama amino acid pamalo 28 ndi 29 a insulin B.

Kodi mankhwalawa amapangidwa kuti?

• Yothetsera jakisoni mu 3 ml makatiriji, m'matumba.
• Syringe cholembera cha insulin.

Palinso mtundu wina wa mankhwalawo womwe muyezo wofanana wa insulin yochepa komanso yapakati. Uku ndiye Humalog Remix 25 ndi Humalog Remix 50.

Kodi mankhwalawa amagwira ntchito bwanji?

Katundu wamkulu wa mankhwalawa ndi kukhazikitsidwa kwa kagayidwe ka glucose. Kuphatikiza apo, Humalog imalimbikitsa kukula kwa minofu ndikuwonjezera mafuta a glycogen mafuta, komanso kupititsa patsogolo kaphatikizidwe ka mapuloteni komanso kuwonjezera kudya kwa amino acid. Mukamagwiritsa ntchito mankhwala a Humalog, insulin lyspro imachepetsa kwambiri hyperglycemia yomwe imachitika mutatha kudya.

Mankhwala ali pafupi kwambiri ndi insulin yaumunthu ndipo ndi mankhwala a ultrashort action. Ubwino wake pamtundu wina ndikuti umayamba kuchitapo kanthu ndipo sililola kuwonjezeka mobwerezabwereza maola angapo jekeseni. Izi ndizofunikira kwambiri kwa odwala omwe amagwira ntchito omwe samva bwino jakisoni nthawi zambiri.

Chifukwa chake, atatha kugwiritsa ntchito mankhwala a Humalog, amayamba kuchita pakatha mphindi 10 mpaka 20. Zambiri pazomwe zimagwira ntchito m'magazi zimawonedwa pambuyo pa mphindi 30 - ola ndi theka. Humalog ili ndi mphamvu yake kwa maola angapo. Hafu ya moyo ndiyifupi ndipo imangokhala ola limodzi.

Tiyeneranso kudziwa kuti ndikamayambitsa mankhwala omwe amaphatikiza insulini yochita kupanga (mwachitsanzo, Humalog, mwachitsanzo), kuchuluka kwa chiwonetsero cha nocturnal hypoglycemia kumachepetsedwa kwambiri mwa odwala, ndipo zimadziwika kuti mankhwalawa amachita mofulumira kwambiri kuposa insulin yaumunthu.

Mankhwala "Humalog" amakhudza onse akulu ndi ana omwe. Malo oyendetsera ndi ofunikira kwambiri, amatha kukhala m'chiuno, phewa, pamimba kapena matako, komanso mlingo komanso kuchuluka kwa insulin.

Humalog Remix 25 ndi chithunzi cha insulin yaumunthu, yomwe imakhala ndi 25% ya insulini yochepa kwambiri komanso 75% ya protamine. Zinapezeka kuti zimagwira mwachangu ndikufika pachimake pantchito, pomwe nthawi ya mankhwalawa ndi pafupifupi maola 15.

Zizindikiro ndi contraindication

Ndani amalimbikitsidwa kugwiritsa ntchito mankhwala a Humalog? Malangizo ogwiritsira ntchito akuwonetsa izi: matenda a shuga mwa akulu ndi ana, omwe amafunikira chithandizo cha insulini kuti athe kukonza shuga. Humalog imalembedwanso ngati matenda a shuga sangathe kuwongolera ndi ma insulini ena. Mu opareshoni ndi matenda wamba.

Ndani samalimbikitsidwa kugwiritsa ntchito Humalog? Malangizo ogwiritsira ntchito amaletsa izi kwa odwala omwe ali ndi hypersensitive pazigawo za mankhwala, komanso ngati pali zotsatirazi: hypoglycemia ndi insulinoma.

Momwe mungamwe mankhwalawa

Kwa wodwala aliyense, mlingo wa mankhwalawa "Humalog" (kanthawi kochepa kake ndi kapangidwe kake) umadziwika ndi dokotala malinga ndi momwe akufunikira. Mankhwalawa amaperekedwa pang'onopang'ono musanadye kapena mutangomaliza kudya.

Administration subcutaneous angathe kuchitika mwa jakisoni, kulowetsedwa, kapena kugwiritsa ntchito insulin. Ngati ndi kotheka, Humalog imatha kutumikiridwa kudzera m'mitsempha.

Mankhwalawa amapaka jekeseni pang'ono m'chiuno, phewa, matako kapena pamimba. Mipando ifunika kusinthidwa nthawi iliyonse kuti isagwiritse ntchito chinthu chomwecho. Mukamapereka mankhwalawa, chisamaliro chimayenera kuthandizidwa kuti musalowe mumtsempha wamagazi. Kuwononga tsamba la jakisoni ndikosavomerezeka. Dokotalayo ayenera kudziwitsa wodwalayo zonse zam'mawu oyamba.

Malangizo a kayendetsedwe ka mankhwala "Humalog"

Choyamba, ziyenera kunenedwa kuti yankho la Humalog liyenera kukhala lowonekera bwino komanso lopanda utoto. Ngati pali zotumphukira kapena kupezeka kwa tinthu tating'onoting'ono, zinthu zotere siziyenera kugwiritsidwa ntchito. Zogulitsirazo zikuyenera kukhala kutentha.

Timalongosola momwe cholembera cha insulin chimagwiritsidwira ntchito:

1. Sambani m'manja musanalowe jakisoni aliyense.
2. Kenako sankhani malo jakisoni.
3. Timachiza ndi antiseptic.
4. Chotsani kapu ku singano.
5. Ndikofunikira kuti mutambasule kapena kutsina khungu ndikulikonza.
6. Ikani singano molingana ndi malangizo.
7. Kanikizani batani.
8. Kenako timachotsa singano, ndikanikizani pang'ono malo a jakisoni kwa masekondi angapo. Sizingatheke kupera.
9. Pogwiritsa ntchito chipewa choteteza, gulani singano ndikuitaya.

Mitsempha yoyeserera ya mankhwalawa imachitika molingana ndi chizolowezi chachipatala kapena kulowetsedwa. Njira zotere zimachitika motsogozedwa ndi dokotala kuchipatala kapena polyclinic, chifukwa ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi.

Humalog imatha kuphatikizidwa ndi pampu yolowetsa insulin. Pankhaniyi, muyenera kutsatira malangizo mosamalitsa. Onetsetsani kuti mwatsata malamulo a asepisi. Ngati pampu ikugwira bwino ntchito kapena njira yolowetsera yatsekeka, kuthamanga kwa glucose kumachitika mwachangu. Musamale mukayamba njirayi. Mukamagwiritsa ntchito pampu, ndi mtundu umodzi wokha wa mankhwala womwe umagwiritsidwa ntchito. Kusakaniza sikuloledwa. Ngati kupatsirana kwa insulin kumayipa, ndikofunikira kuchitapo kanthu mogwirizana ndi malangizo ndikudziwitsa dokotala mwachangu.

Tiyenera kudziwa kuti kukonzekera kwa Humalog Remix 25 kumasiyanitsidwa ndi kusasinthika ndi mtundu wake. Ili ndi yankho la madzi oyera oyera osisakaniza, musanagwiritse ntchito komwe kuli kofunika kuti muwatenthe bwino m'manja, koma osakugwedeza kuti thovu lisapangike. Njira yothetsera vutoli imayenera kukhala yopanda pake. Katunduyu sakuyenera kugwiritsidwa ntchito ngati mapangidwe a flakes apanga. Pakuyambitsa kwake, mutha kugwiritsa ntchito, komanso mankhwalawa "Humalog", "QuickPen" - cholembera, syringe, yosavuta kugwiritsa ntchito. Momwe mungagwiritsire ntchito, tafotokozera pamwambapa.

Chinsinsi chakugwiritsa ntchito Humalog Remix 25 ndikuti sichingathe kutumikiridwa kudzera m'mitsetse. Mlingo wa mankhwalawa amasankhidwa ndi dokotala payekhapayekha.

Zotsatira zoyipa za mankhwala "Humalog"

Malangizo ogwiritsira ntchito amafotokozera zovuta zomwe zimachitika pakhungu pogwiritsa ntchito mankhwalawa:

• Hypoglycemia.
• Kutaya chikumbumtima.
• Thupi lawo siligwirizana: redness, kuyabwa, kutupa, urticaria.
• Tachycardia, kutsitsa magazi.
• Kuchulukitsa thukuta.
• Angioneurotic edema.
• Lipodystrophy pamalo opangira jekeseni.

Zizindikiro za mankhwala osokoneza bongo

Ma insulini alibe malire ofotokoza bongo. Popeza aliyense ali ndi kuchuluka kwake kwa kagayidwe ndi shuga, izi zimangokhala zokha. Komabe, muyenera kudziwa zomwe zikuluzikulu zakupereka mlingo, ngati thupi silitha kupirira ndipo hypoglycemia imachitika. Izi zimatha kuchitika ngati vuto la kuperewera kwa vuto la kuperewera kwa zakudya m'thupi kapena kugula kwa mphamvu zambiri.

Kuchita insulin kwambiri kungayambitse hypoglycemia. Zizindikiro zake ndi izi:

• Zofooka, kupanda chidwi.
• Kutaya chikumbumtima.
• Kuchulukitsa thukuta.
• Zovuta za mtima.
• Kubweza
• Mutu.

Muyenera kudziwa momwe mungathanirane ndi hypoglycemia yolimbitsa thupi. Kuti muchite izi, ingotengani shuga kapena idyani chinthu chomwe chili ndi shuga. Pambuyo povutitsidwa chotere, mungafunike kusintha kwa mlingo, komanso kusintha kwa zolimbitsa thupi.

Matenda owopsa a hypoglycemia ali ndi zizindikiro izi:

• Coma
• Zingwe.
• Matenda a mitsempha.

Kuthetsa mawonetsedwe otere ndikotheka kuyambitsa "Glucagon" intramuscularly kapena subcutaneally. Onetsetsani kuti mwasintha mphamvu. Ngati wodwala yemwe ali ndi insulini sakulabadira makupidwe a Glucagon, kulowetsedwa kwamkati mwa glucose wokhazikika kungachitike. Wodwala akakhala kuti akomoka, ndikofunikira kuchita intramuscular kapena subcutaneous makonzedwe a Glucagon. Munthu akazindikira, ndikofunikira choyamba kumudyetsa. Mungafunikire kuwonjezera kuchuluka kwa chakudya chamagulu muzakudya zanu. Kuwonanso thupi ndi kuwerenganso kuyenera, popeza kuukira kwa hypoglycemia kungayambenso.

Zokhudza kugwiritsa ntchito mankhwalawa

Kugwiritsa ntchito mankhwala monga Humalog, muyenera kudziwa zinthu zina zomwe mungagwiritse ntchito mankhwalawa:

1. Sinthani kuchokera ku mtundu wina wa insulin kupita ku wina uyenera kuyang'aniridwa ndi dokotala. Popeza wopanga, mtundu, mankhwala osiyanasiyana, komanso mtundu wazomwe akupanga kapena mtundu wake ndizofunikira kwambiri. Ndizofunikira kudziwa kuti ndikusintha kuchokera ku insulin ya nyama ndikusintha mtundu wa anthu wofunikira pamafunika.
2. Ndikofunikira kuyang'anitsitsa wodwalayo ngati atembenuka kuchokera ku insulin yakuchokera kwa nyama kupita ku insulin ya anthu. Mwina poyambira kusapezeka kwa zisonyezo zilizonse, kapena ofanana kwambiri ndi omwe adasamutsidwa kale, komabe, muyenera kuyang'anira kuchuluka kwa shuga m'magazi. Ngati mankhwalawo sanasinthidwe, khungu limatha kuzindikira, kukomoka, kapena kufa.
3. Ngati mulingo wambiri suyendetsedwa kapena mankhwalawa amasiya mwadzidzidzi ndimatenda a shuga, izi zimayambitsa matenda a hyperglycemia ndi matenda ashuga a ketoacidosis. Ichi ndi chiopsezo chowopsa chomwe chimasokoneza moyo wa wodwala.
4. Odwala omwe ali ndi vuto la impso ndi hepatic, kufunika kwa insulin kungachepe, chifukwa njira za gluconeogeneis ndi insulin metabolism zimachepetsedwa. Odwala omwe ali ndi matenda osatha a chiwindi, kuchuluka kwa insulini kungafune kuchuluka kwa mlingo.

Kukula kwa mulingo wofunikira ndikofunikira pazotsatira izi:

• Mavuto azisoni.
• Matenda opatsirana.
• Kuwonjezeka kwa chakudya chamafuta.

Komanso, zolimbitsa thupi ndi kusintha kwa zakudya zimakhudza kuchuluka kwa shuga m'magazi. Chiwopsezo cha hypoglycemia chimawonjezeka ngati mumachita masewera olimbitsa thupi mutangochoka patebulo.

Ngati simutsatira mlingo wa kukonzekera kwa insulin, chiopsezo chotayika chikuwonjezereka komanso kuchepa kwa liwiro la zotulukapo zama psychomotor ndikotheka.

Odwala omwe ali ndi vuto losachedwa kuwona zizindikiro za hypoglycemia kapena amakonda kubwereza amayenera kuyesa kuyendetsa bwino. Mmodzi ayenera kukhala osamala kwambiri poyendetsa makina ndi makina.

Hypoglycemia yofatsa imatha kuyimitsidwa yokha mwa kutenga magalamu makumi awiri a glucose kapena chakudya chomwe chili ndi chakudya chamagulu ambiri. Kuukira konse kwa hypoglycemia kuyenera kudziwitsidwa kwa dokotala.

Ngati mukufuna kugwiritsa ntchito mankhwala ena, muyenera kufunsa katswiri wazomwe zimayenderana ndi mankhwala a Humalog. Tikuuzaninso zambiri za izi mtsogolo.

Kodi mankhwala a Humalog amalumikizana bwanji ndi mankhwala ena

Kuchita bwino kwa mankhwalawa "Humalog" kumachepa ndi kugwiritsa ntchito mankhwala monga awa:

• Kulera kwamlomo.
• Glucocorticosteroids.
• Kukonzekera kwa mahomoni a chithokomiro.
• Danazol
• Beta₂-adrenomimetics (kuphatikiza "Ritodrin", "Salbutamol", "Terbutaline").
• Tricyclic antidepressants.
• Zothandiza kuchokera ku phenothiazine.
• Thiazide okodzetsa.
• Nicotinic acid
• Chlorprothixen.
• "Lithium carbonate."
• Diazoxide.
• Isoniazid.

Mankhwala omwe amalimbikitsa zochitika za Humalog:

• Beta blockers.
• Mankhwala okhala ndi Ethanoli.
• Tetracyclines.
• Ma salicylates (makamaka acetylsalicylic acid).
• Anabolic steroids.
• Sulfonamides.
• Mao zoletsa.
• ACE zoletsa.
• Angiotensin receptor antagonists.
• "Octreotide."

Komanso, kuphatikiza mankhwala a Humalog ndi kukonzekera kwa insulin ya nyama sikuloledwa.

Moyang'aniridwa ndi dokotala, kugwiritsa ntchito molumikizana kwa mankhwala a Humalog omwe ali ndi insulin yayitali kapena anthu omwe ali ndi mankhwala a hypoglycemic - zotumphukira za sulfonylurea - ndizotheka.

Kugwiritsa ntchito mankhwala kwa ana

Monga tanena kale, Humalog ndi insulin yotsitsimutsa kwambiri, ndipo payenera kukhala chifukwa china chosamutsira mwana ku mankhwalawa. Izi zikuphatikiza ndi izi:

• Kusintha kosangalatsa kwa mwana komanso kusasamala zakudya.
• Kukula kwa zakudya mu achinyamata.
• Kukonzekereratu kwa kuukira kwa hypoglycemia kumapeto kwa usiku ndi usiku.
• Kusintha kwakukuru m'magazi a magazi, mapangidwe a spasmodic a matenda.
• Kugwiritsa ntchito insulini mwachidule sikunaperekenso chindapusa.

Ana aang'ono amakhala nthawi yayitali akudya, motero amapatsidwa insulin yochepa pakudya.

Humalog iyenera kugwiritsidwa ntchito kwa ana motsatira malangizo a dokotala, ngati pakufunika kuti insulini ithe mwachangu.

Humalog ya azimayi oyembekezera komanso oyala

Ndikofunika kudziwa kuti amayi omwe ali ndi matenda ashuga omwe akukonzekera kutenga pakati amafunika kuwongolera kuchuluka kwa shuga m'magazi, komanso kuunikanso kwachipatala. Dokotala wopezekapo ayenera kudziwitsidwa pasadakhale.

Panalibe zoyipa zilizonse za mankhwala a Humalog pa thupi la mkazi kapena pa mwana wosabadwa. Mankhwala samapita mkaka wa m'mawere ndipo samakhudza kukula kwa mwana wosabadwayo.

Mankhwala a insulin amachitika mwa amayi apakati kapena oyembekezera kuti akhale ndi shuga. Amadziwika kuti mu 1st trimester kufunika kwa insulin kumakhala kotsika kuposa 2nd ndi 3. Pogwira ntchito, komanso pambuyo pake, kufunika kwa insulin kumatha kuchepa. Kusintha kwa mlingo kuyenera.

Mankhwala a Humalog ndi abwino kwa amayi onse apakati komanso oyembekezera. Ndikofunika kukumbukira kuti adatchulidwa ndi adotolo ndipo kusintha kuchokera ku mtundu wina kupita kwina kuyenera kuchitika mosamalidwa ndi adokotala.

Kodi mtengo wamankhwala "Humalog" ndi chiyani, komanso zomwe zikufanana, tikambirananso.

Mndandanda wamankhwala ndi mtengo wake

The fanizo la mankhwala a Humalog akuphatikizira insulin:

• "Actrapid MS."
• "Berlinsulin N Cholembera Wofala."
• "B-Insulin S. Ts.".
• Depot Insulin C
• Isofan.
• "Insulin C".
• "Iletin."
• "Insuman Comb."
• "Intral SPP".
• "Combinsulin C".
• "Monosuinsulin C".
• "Pensulin."
• Rinsulin.
• Ultratard NM.
• "Nyumba 40."
• Humulin.

Kukonzekera kwa analogi ndi chinthu chomwechi:

• Kusintha kwa Humalog 25
• Kusintha kwa Humalog 50
• "Insulin Lyspro."

Ndikofunika kudziwa kuti mankhwala a Humalog omwe amapezeka mu pharmacy amaperekedwa mosamalitsa malinga ndi zomwe dokotala wakupatsani. Mtengo ndiwodziwika pakati pamankhwala apano ndipo umachokera ku ma ruble 1600-1900 pazinthu 5 zama cartridge.

Mukasankha kusintha Humalog, ndi adokotala okha omwe angakupatseni fanizo. Osazichita nokha, chifukwa moyo wanu umadalira.

Ndemanga za mankhwala "Humalog" ndi maubwino ake

Ndemanga za odwala zimangokhala zabwino. Ambiri amagwiritsa ntchito mankhwalawa kwa zaka zambiri. Humalog (makatiriji omwe amaphatikizidwa ndi cholembera cha QuickPen) ndiosavuta kugwiritsa ntchito. Anthu amadziwa kusakhalapo kwa mavuto. Mankhwala amayamba kuchita zinthu mwachangu ndipo amagwira ntchito mkati mwa maola 1.5. Poyerekeza ndi njira zina za gululi, ambiri amawona mtundu wake wapamwamba. Komanso, odwala ambiri amakhutira ndi mtengo wa mankhwalawa a Humalog (mtengo wasonyezedwa pamwambapa). Amazindikira kuthekera kwake kwabwino polimbana ndi shuga wambiri.

Komanso, musaiwale kuti kusintha kuchokera ku mankhwala kupita kwina ndikuyenera kuyang'aniridwa ndi dokotala.

Humalog (wodwala amawunikira) ndi mankhwala apamwamba kwambiri. Tiyenera kudziwa zabwino za insulin action insulins, yomwe ndi Humalog:

• Mlingo wa postprandial glycemia umachepa.
• Mlingo wa HbA1 umachepa.
• Pazonse, kuchuluka kwa kagayidwe kazakudya m'thupi kumachuluka.
• Moyo wa wodwala umachulukirachulukira.
• Mankhwala amatha kumwedwa musanadye kapena pambuyo pake, monga momwe dokotala angapangire.
• Mochepetsa kwambiri kuchuluka kwa matenda a hypoglycemia masana ndi usiku.
• Ndikotheka kugwiritsa ntchito zakudya zosinthika.
• Kugwiritsa ntchito mosavuta komanso kosavuta kugwiritsa ntchito.

Mankhwala samayima, ndipo mankhwala ochulukirachulukira akuwonekera omwe amathandiza munthu kuthana ndi matenda monga matenda a shuga. Khalani ndi chidwi ndi thanzi lanu ndipo musasiye zisonyezo zoyambirira osakumanapo nazo, moyo wanu ungadalire izi.

Humalog: malangizo ogwiritsa ntchito. Zambiri bwanji?

Ultrashort insulin Humalog: phunzirani zonse zomwe mukufuna. Pansipa mupeza malangizo ogwiritsira ntchito olembedwa m'chinenerochi. Werengani mayankho a mafunso:

Ikufotokozanso njira zabwino zakuthandizira zomwe zimakulolani kuti mukhale ndi shuga 3.9-5,5 mmol / L khola maola 24 patsiku, monga momwe mumakhalira ndi anthu athanzi. Dongosolo la Dr. Bernstein, wokhala ndi vuto la glucose metabolism kwa zaka zopitilira 70, limakupatsani 100% yodzitetezera ku zovuta zovuta. Onani pulogalamu ya Type 1 Diabetes Control Program kapena Step-by-step Type 2 Diabetes Treatment Program kuti mumve zambiri.

Ultrashort Insulin Humalog: Nkhani Yatsatanetsatane

Tsamba la endocrin-patient.com silikulimbikitsa kugula mapiritsi a insulin ndi matenda a shuga kuchokera m'manja, malinga ndi malonda.

Kugula kuchokera kwa anthu, mukuyenera kulandira mankhwala osagwira ntchito, osagwira ntchito. Akasungidwa, Humalog nthawi zambiri imakhala yowonekera bwino. Mwa mawonekedwe a insulini ndizosatheka kuweruza mtundu wake.

Chifukwa chake, muyenera kugula kokha mumafakitale odziwika, odziwika bwino, omwe amatsatira malamulo osungira.

Malangizo ogwiritsira ntchito

Mukabayidwa kukonzekera kwa Humalog, monga mtundu wina uliwonse wa insulin, muyenera kutsatira zakudya.

Mtundu wa matenda a shuga a 2 Mtundu woyamba wa shuga Zakudya tebulo No. 9 Masamba a sabata: Zitsanzo

Sonyezani shuga lanu kapena sankhani jenda kuti mulimbikitsidwe

Anthu ambiri omwe ali ndi matenda ashuga omwe amadzilimbitsa ndi insulin yofulumira samapeza mwayi wopewa kufinya kwa hypoglycemia. M'malo mwake, izi siziri choncho. Mutha kusunga shuga wokhazikika ngakhale ndi matenda oopsa a autoimmune. Ndipo makamaka, ndi matenda a shuga a 2 ochepa.

Palibe chifukwa chakuwonjezera kuchuluka kwa shuga m'magazi anu kuti mudzilimbitse nokha motsutsana ndi hypoglycemia yoopsa. Onerani kanema pomwe Dr. Bernstein akufotokoza nkhaniyi ndi bambo wa mwana yemwe ali ndi matenda a shuga 1. Phunzirani momwe mungasinthire zakudya zopatsa thanzi komanso mulingo wa insulin.

Onerani kanema wa Dr. Bernstein. Dziwani mwatsatanetsatane kuchuluka kwa maola omwe Humalog Insulin amachita, momwe imakhudzira chakudya chamagulu. Mvetsetsani momwe Mlingo wa mankhwalawa umasiyanirana ndi odwala omwe ali ndi vuto la matenda ashuga a 2 komanso anthu ochepa thupi la matenda ashuga 1, komanso ana a matenda ashuga.

Otsatirawa ndiwowonjezera pazamankhwala omwe ali ndi insulin lispro.

Humalog ndi chiyani insulin? Kodi ndizitali kapena zazifupi?

Ichi ndi mahomoni a ultrashort, omwe ali othamanga kwambiri. Imayamba kuchita pafupifupi nthawi yomweyo - osapitirira mphindi 15-20 pambuyo pa kubayidwa. Izi ndizothandiza panthawi yomwe muyenera kuzimitsa msanga magazi.

Komabe, pakhoza kukhala zovuta mu odwala matenda ashuga omwe amatsatira zakudya zamafuta ochepa. Chifukwa Humalog, yomwe idayambitsidwa chakudya chisanachitike, imayamba kuchita zinthu mwachangu kuposa zakudya zama carb ochepera zomwe zimamwa.

Zotsatira zake, shuga wodwala matenda ashuga amatha kutsika kwambiri.

Mwina Humalog ndiye wothamanga kwambiri wamitundu yonse ya insulin. Ngakhale opanga ma analogu omwe amapikisana naye sangavomereze zomwe ananenazi.

Ati mankhwala awo a Apidra ndi NovoRapid ayambanso kuchita zinthu mwachangu. Palibe zambiri zenizeni pankhaniyi. Kwa odwala matenda ashuga osiyanasiyana, mitundu yambiri ya insulin imagwira ntchito mosiyanasiyana.

Zowona zenizeni zimatha kupezedwa mwa kuyesa ndi zolakwika.

Mitundu ya insulini: Momwe mungasankhire mankhwala a insulin yayitali usiku ndi m'mawa Muwerengera kuchuluka kwa insulin musanadye chakudya

Kodi mungasankhe bwanji mulingo wa Humalog insulin pa mkate mkate (XE)?

Mochulukitsa zakudya zomwe anthu odwala matenda ashuga amapeza, ndiye kuti ayenera kupaka insulin asanadye. Kupereka kwa zakudya zamagalimoto kumatha kuyezedwa m'magawo a mkate kapena magalamu. Kuwerengera kwamawerengero azakudya ndi mtundu wofunikira wa Humalog zimapezeka pano.

Mwazi wanu wamagazi ungakhale wabwino kwambiri ngati mupita zakudya zamafuta ochepa. Sizikupanga nzeru kwa odwala matenda ashuga omwe amatsata izi kuti awerenge chakudya m'magawo a mkate. Chifukwa kudya kwa tsiku ndi tsiku kwamakina osaposa 2,5 XE, komanso kwa ana ochepera.

Dr. Bernstein amalimbikitsa kuwerengetsa chakudya m'magalamu, osati XE. Humalog ndi insulin yolimba yomwe imagwira ntchito mwachangu komanso modzidzimutsa. Sizigwirizana bwino ndi zakudya zamafuta ochepa. Ganizirani kusintha kwa icho kukhala Actrapid.

Ponena za ana, ndizomveka kusinthira mwana wodwala matenda ashuga kuti akhale zakudya zamafuta ochepa, gwiritsani ntchito Actrapid kapena mankhwala ena achidule m'malo mwa Humalog insulin, komanso kukana kugwiritsa ntchito pampu ya insulin. Werengani nkhani yoti “Matenda a Ana A shuga” kuti mumve zambiri.

Kodi zingakwanitse bwanji?

Muyenera kumugaya Humalo katatu patsiku musanadye. Komabe, mlingo ndi ndandanda ya jakisoni wa insulin aliyense wodwala matenda ashuga ayenera kusankhidwa payekhapayekha. Kugwiritsa ntchito mapulani okonzedwa sangapereke chiwongolero chabwino cha matenda a shuga. Werengani mwatsatanetsatane nkhani "Kuwerengera mlingo waifupi ndi wa insulin ya m'mimba musanadye."

Chithandizo cha boma chimalimbikitsa kugwiritsa ntchito Humalog ndi mawonekedwe ake monga insulin yachangu musanadye. Jekeseni zimachitika mphindi 15 musanadye.

Komabe, kwa odwala omwe ali ndi matenda amtundu wa 1 komanso amtundu wa 2, omwe amatsata zakudya zamafuta ochepa, ndibwino kuti mupeze insulin yochepa, monga Actrapid, m'malo mwa ultrashort musanadye.

Chifukwa kuthamanga kwa zochita zazifupi kumayenderana bwino ndi kusinthidwa kwa zinthu zovomerezeka ndi zotsimikizika.Werengani zambiri mu nkhani "Mitundu ya Insulin ndi Zotsatira Zawo".

Humalog mwachangu kuposa mankhwala ena amatha kupangitsa kuti shuga azikhala kwambiri. Chifukwa chake, ndibwino kukhala nanu pokhapokha pachitika ngozi. Komabe, ochepa omwe ali ndi matenda ashuga omwe akufuna kugwiritsa ntchito onse aifupi ndi a insulin. Ngati muthana ndi kagayidwe kakang'ono ka shuga wanu wamafuta ochepa, mungathe kudutsa ndi mankhwala osakhalitsa.

Kodi jakisoni aliyense amatalika bwanji?

Jekeseni aliyense wa mankhwala a Humalog amatha pafupifupi maola anayi. Anthu odwala matenda ashuga omwe amatsata zakudya zama carb ochepa amafunika Mlingo wambiri wa insulin. Nthawi zambiri imayenera kuchepetsedwa kuti ipange jekeseni woyenera wa mankhwala osakwana 0,5-1.

Humalog imatha kuchepetsedwa osati kwa ana omwe ali ndi matenda a shuga 1, komanso odwala akuluakulu. Chifukwa ndi mankhwala amphamvu kwambiri. Mukamagwiritsa ntchito mankhwala ochepa, insulin imasiya kugwira ntchito mwachangu kuposa momwe amafunidwira.

Mwina jakisoni amatha kumapeto kwa maola awiri ndi awiri ndi awiri.

Pakapita jakisoni iliyonse ya kukonzekera kwa ultrashort, muyezetse magazi osachepera maola atatu pambuyo pake. Chifukwa kufikira nthawi ino, mlingo wa insulin wolandirira ulibe nthawi kuti uwonetse mphamvu yake yonse.

Monga lamulo, odwala matenda ashuga amapereka jakisoni wa insulin yofulumira, idyani, kenako kuyeza shuga kale chakudya chotsatira. Kupatula pokhapokha ngati wodwala akumva zizindikiro za hypoglycemia.

Zikatero, muyenera kudziwa nthawi yomweyo kuchuluka kwa shuga m'magazi ndipo ngati kuli koyenera, chitanipo kanthu.

Kodi pali kusiyana kotani pakati pa Humalog ndi Humalog Remix?

Prost proteni Hagedorn (NPH), yomwe imachepetsa zochita za insulin, yawonjezeredwa ku Humalog Remix 25 ndi 50. Mitundu ya insulin iyi imasiyana ndi zomwe zili mu NPH. Mowonjezereka mankhwala, kumawonjezera zochita za jakisoni.

Mankhwalawa ndi otchuka chifukwa amatha kuchepetsa kuchuluka kwa jakisoni tsiku ndi tsiku, kuchepetsa njira ya insulin. Komabe, sangapereke magazi moyenera. Chifukwa chake, Dr. Bernstein ndi tsamba la odwala endocrin.

com musalimbikitsa kuti mugwiritse ntchito.

Proteni yosagwira nawo mbali ya Hagedorn nthawi zambiri imayambitsa matupi awo sagwirizana ndi mavuto ena. Kuti mumve zambiri, onani nkhani yakuti "Mitundu ya Insulin ndi Zotsatira Zawo". Kugwiritsa ntchito Humalog Remix 25 ndi 50 ndi njira yachindunji yovuta yovuta kwambiri komanso yodwala matenda ashuga.

Mitundu ya insulini imeneyi imakhala yoyenera kwa odwala matenda ashuga okalamba okha amene amakhala ndi moyo wocheperako kapena amene ali ndi vuto lotere la maganizo. Magulu ena onse a odwala ayenera kugwiritsa ntchito Humalog yoyera yokha.

Ndipo ndibwino kusinthana ndi zakudya zamafuta ochepa ndikuyesa jakisoni wa Actrapid musanadye.

Maso (retinopathy) Impso (nephropathy) Matenda a shuga Atsitsi: miyendo, mafupa, mutu

Ndi insulin iti yomwe ili bwino: Humalog kapena NovoRapid?

Pangakhale palibe chidziwitso cholondola choyankha funso ili, lomwe nthawi zambiri limafunsidwa ndi odwala. Chifukwa mitundu yambiri ya insulini imakhudza aliyense wodwala matenda ashuga payekhapayekha. Onse a Humalog ndi NovoRapid ali ndi mafani ambiri. Monga lamulo, odwala amapaka jakisoni mankhwala omwe amapatsidwa kwaulere.

Ziwengo zimakakamiza ena kuti asinthe mtundu wina wa insulin kupita ku wina.

Tikubwerezanso kuti ngati mutsatira zakudya zamafuta ochepa, ndibwino kugwiritsa ntchito mankhwala achidule, monga Actrapid, m'malo mwa Humalog, NovoRapid kapena Apidra mwachangu, musanadye. Ngati mukufuna kusankha mitundu yoyenera ya insulin yowonjezera komanso yachangu, ndiye kuti simungathe kuchita popanda kuyesa komanso zolakwika.

Mndandanda wa insulin Humalog (lispro) ndi Apidra (glulisin) ndi NovoRapid (aspart). Kapangidwe ka mamolekyulu awo ndiosiyana, koma pochita nawo zilibe kanthu. Dr. Bernstein akuti Humalog ndi yachangu komanso yamphamvu kuposa anzawo. Komabe, si odwala onse omwe amatsimikizira izi.Pamabwalo a odwala matenda ashuga olankhula Chirasha, mutha kupeza mawu otsutsa.

Odwala omwe ali ndi matenda amtundu wa 1 komanso a 2 omwe amatsatira zakudya zotsika kwambiri amatha kuyesa kulowetsanso insulin lyspro ndi mankhwala osakhalitsa. Mwachitsanzo, pa Actrapid. Pamwambapo zalembedwa mwatsatanetsatane chifukwa chake izi ndizoyenera kuchita. Komanso, insulin yochepa ndiyotsika mtengo. Chifukwa adalowa m'msika zaka zambiri m'mbuyomu.

Insulin Humalog: momwe mungagwiritsire ntchito, kuchuluka kwake ndizovomerezeka komanso mtengo wake

Ngakhale kuti asayansi adatha kubwereza molekyulu yonse ya insulin yomwe imapangidwa m'thupi la munthu, zochita za mahomoni adasinthiratu chifukwa zimafunikira nthawi yoyenera kunyamulidwa m'magazi. Mankhwala oyamba osinthika anali insulin Humalog. Imayamba kugwira ntchito patangodutsa mphindi 15 jakisoni, choncho shuga yochokera m'mwaziyo imasamutsidwira minofu yake munthawi yake, ndipo ngakhale hyperglycemia yochepa siyimachitika.

Poyerekeza ndi ma insulins omwe adapangidwa kale, Humalog ikuwonetsa zotsatira zabwino: mwa odwala, kusinthasintha kwa tsiku ndi tsiku kwa shuga kumachepetsedwa ndi 22%, magirisi am'magazi amayenda bwino, makamaka masana, ndipo mwayi wa kuchepa kwambiri kwa hypoglycemia umachepa. Chifukwa chachangu, koma chokhazikika, insulin iyi imagwiritsidwa ntchito kwambiri mu shuga.

Mlingo

Njira yothetsera kulowetsedwa kwa mtsempha wamagetsi.

1 ml muli:
ntchito: insulin lispro 100 IU,
zokopa: glycerol (glycerin) 16 mg, metacresol 3.15 mg, zinc oxide q.s. mpaka Zn ++ 0,0197 mg, sodium hydrogen phosphate heptahydrate 1.88 mg, hydrochloric acid solution 10% ndi / kapena sodium hydroxide solution 10% q.s. mpaka pH 7.0 - 8.0. madzi a jekeseni q.s. mpaka 1 ml.

Yankho lomveka, lopanda utoto.

Zizindikiro zogwiritsidwa ntchito

Choyamba muyenera kuthana ndi kapangidwe kake. Chomwe chimagwiritsa ntchito mankhwalawa ndi insulin lispro.

Koma pakati pazosakaniza zothandizira mungapeze izi: glycerin, metacresol, zinc oxide, sodium hydrogen phosphate heptahydrate, yankho la hydrochloric acid, komanso yankho la sodium hydroxide.

Kuyimitsidwa kwa kayendetsedwe ka intravenous and subcutaneous ali ndi mawonekedwe amadzimadzi omveka bwino omwe alibe mthunzi. Mankhwalawa amapezeka m'makatoni, omwe amakhala ndi makatoni.

Ponena za momwe mungagwiritsire ntchito, mankhwalawa amalembedwa kuti azikhala ndi shuga. Pamafunika matendawa, omwe amafunika chithandizo chapadera cha insulin. Chifukwa cha kugwiritsidwa ntchito kwake, ndizotheka kupitiliza kuchuluka kwa shuga m'thupi pamlingo woyenera.

Mlingo ndi makonzedwe

Mlingo wa mankhwalawa umatsimikiziridwa payekhapayekha ndi katswiri wowachiritsa. Zimatengera zosowa za wodwala. Mankhwalawa amatha kuperekedwa kwa mphindi khumi ndi zisanu asanadye. Pazifukwa zofunikira kwambiri, amaloledwa kupereka jakisoni ndi mankhwala mukangodya.

Mphamvu yotentha ya mankhwala omwe amaperekedwa amayenera kufanana ndi kutentha kwa firiji. Humalog imayendetsedwa pansi pa khungu mawonekedwe a jakisoni kapena kulowetsedwa kwa subcutaneous kulowetsa pampu yapadera ya insulin.

Insulin Humalog Remix 25

Ngati mukufunikira kwambiri (kukhalapo kwa ketoacidosis, matenda owopsa, nthawi yanthawi yopangira opaleshoni kapena pambuyo pa opaleshoni), mankhwala omwe atchulidwa angathenso kuthandizidwa. Jakisoni wotsekemera uyenera kuchitika patsogolo, miyendo, matako ndi m'mimba.

Chifukwa chake, gawo limodzi la thupi silikulimbikitsidwa kuti ligwiritsidwe ntchito kangapo kamodzi masiku makumi atatu aliwonse. Ndi mtundu wamtundu wa mankhwalawa Humalog, muyenera kusamala kwambiri. Muyenera kusamala kuti mupeze mankhwalawo m'mitsempha yaying'ono yamagazi - capillaries.

Pambuyo pa jekeseni, gawo lomwe lakhudzidwalo liyenera kutenthedwa. Wodwala ayenera kuphunzitsidwa momwe amapangira insulin.

Ponena za momwe mungagwiritsire ntchito, chinthu choyamba muyenera kukonzekera jakisoni. Yankho la mankhwalawa Humalog lili ndi kusasinthika koonekeratu. Palibe mtundu.

Sitikulimbikitsidwa kugwiritsa ntchito njira yothina, yothinima pang'ono kapena yopaka utoto pang'ono. Ndizoletsedwa kuperekera mankhwala omwe amakhala ndi tinthu tosakhazikika.

Mukakhazikitsa katiriji wapadera mu cholembera (cholembera -), kusunga singano ndikubaya ma pancreatic mahomoni oyambira, muyenera kutsatira malangizo omwe apezeka mu malangizo a mankhwalawo.

Ponena za mawu oyamba, ziyenera kutsagana ndi izi:

1. Choyambirira kuchita ndikusamba m'manja ndi sopo,
2. Kenako, muyenera kudziwa malo omwe jakisoni,
3. muyenera kusamalira mosamala malo osankhidwa ndi antiseptic,
4. ndiye muyenera kuchotsa chipewa mu singano,
5. ndiye ndikofunikira kukonza khungu pakukoka kapena kuphimba khola lowoneka bwino. Ikani singano molingana ndi malangizo omwe aphatikizidwa ogwiritsa ntchito cholembera,
6. Tsopano muyenera dinani batani,
7. mukatero, chotsani singano ndikufinya jakisoni kwa masekondi angapo,
8. sikulimbikitsidwa kupaka jakisoni malo,
9. gwiritsani ntchito kapukusi wa singano, ndipo mumasuleni ndi kuiwononga,
10. mawebusayiti a jakisoni ayenera kusinthidwa kuti malo omwewo asagwiritsidwe ntchito mopitilira kamodzi masiku makumi atatu.

Intravenous makonzedwe a mankhwala Humalog ayenera kuchitika malinga ndi zosavuta matenda mchitidwe jekeseni. Mwachitsanzo, jakisoni wamtunduwu uyenera kuchitika pogwiritsa ntchito kulowetsedwa. Nthawi yomweyo, ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi a wodwala.

Makina apadera a kulowetsedwa ndi zozungulira kuchokera ku 0, IU / ml mpaka 1 IU / ml ya mankhwala omwe amagwira mankhwalawa mu 0.8% sodium chloride solution kapena 5% dextrose yokhazikika pamtunda wotentha kwa masiku awiri.

MiniMed insulin pampu

Subcutaneous jakisoni wa mankhwalawa amagwiritsidwa ntchito Pampu Zochepetsetsa komanso Disetronic pobayira insulin.. Pankhaniyi, muyenera kutsatira mosamalitsa malangizo omwe aphatikizidwa. Njira ya kulowetsedwa iyenera kusinthidwa masiku awiri aliwonse.

Mukalumikiza chida, samalani malamulo aseptic. Pakakhala kuchepa kwadzidzidzi kwa ndende ya magazi, njirayi iyenera kusiyidwa mpaka izi zitheke.

Pali nthawi zina pamene kusayenda bwino kwa cholembera cholembera insulin kungayambitse kuchuluka kwa shuga m'magazi.

Panthawi yomwe akukayikira kuti akuphwanya insulin, muyenera kutsatira malangizowo, ndipo ngati kuli koyenera dziwitsani dokotala wanu munthawi yake.

Mukamagwiritsa ntchito pampu, mankhwala omwe amatchedwa Humalog safunikira kuphatikizidwa ndi mitundu ina ya insulin yofanana ndi ya munthu.

Ngati kuchepa kwakukulu kwa shuga m'magazi, ndikofunikira kudziwitsa dokotala wanu za izi nthawi yomweyo. Mutha kuperekanso mawonekedwe a zotere: tikulimbikitsidwa kuti muchepetse kapena kuletsa kwathunthu makonzedwe a insulin.

Zotsatira zoyipa

Zosafunika mu thupi zimakhudzana ndi zotsatira zazikulu za mankhwalawa: kugwa kwamwadzidzidzi mu shuga.

Hypoglycemia yambiri ikhoza kutha kuyambitsa chikumbumtima (chomwe chimatchedwa hypoglycemic coma), ndipo nthawi zina ngakhale kufa.

Ponena za zovuta zomwe zimachitika, zakomweko ndizotheka. Amasiyanitsidwa ndi khungu rede, kutupira, kuyabwa, komanso zizindikiro zina zomwe zimasowa patatha masiku angapo. Nthawi zambiri pamakhala zisonyezo zatsatanetsatane za kusalolera kwa mankhwalawo.

Amachitika kawirikawiri, koma zazikulu.Izi zimadziwika ndi kuyabwa, urticaria, zidzolo, angioedema, kutentha thupi, kufupika, kutsitsa magazi, tachycardia, komanso hyperhidrosis.

Pali zovuta zingapo zomwe zimapangitsa kuti thupi lanu lichepe. Pazinthu zakumudzi zomwe zimachitika, munthu amatha kusiyanitsa monga kuchepa kwamafuta am'madzi pamalo a jakisoni.

Contraindication

Matenda a shuga amawopa mankhwalawa, ngati moto!

Muyenera kungolemba ...

Akatswiri amaletsa mankhwalawa kugwiritsidwa ntchito pamaso pa hypoglycemia ndi hypersensitivity ku zigawo zikuluzikulu za mankhwalawa.

Ponena za pakati ndi kuyamwitsa, pakadali pano sipanakhale chifukwa chosavomerezeka cha pancreatic timalo ta kubereka mwana pakubala.

Tiyeneranso kudziwa kuti maphunziro oyenerera sanachitike. Cholinga chachikulu cha chithandizo ndi insulin panthawi yapakati chimatengedwa kuti pakhale shuga.

Ndikofunikira kudziwa kuti zofuna za mahomoni nthawi zambiri zimatsika mu trimester yoyamba ndikuwuka kwachiwiri ndi kwachitatu. Pa nthawi yobereka komanso pambuyo pobadwa kwa mwana, kufunika kwa insulini kumatha kuchepa mwadzidzidzi.Oyimira maubwenzi ofooka omwe amakhala ndi matenda ashuga ayenera kudziwitsa dokotala za nthawi yomwe akubereka kapena akukonzekera kubereka.

Pakunyamula mwana wosabadwayo, odwala endocrinologist omwe ali ndi vuto lotere ayenera kuwongolera zomwe zili mumkhwalawa.

Ndikofunikira kudziwa kuti mukamayamwitsa, kuwongolera pang'ono kuchuluka kwa mahomoni opanga pancreatic angafunike.

Komanso, ngati pakufunika, muyenera kutsatira zakudya zapadera. Monga lamulo, zofuna za insulini zitha kugwera pamaso pa chiwindi cholephera. Anthu omwe ali ndi matendawa amakhala ndi kunyentchera kwambiri kwa pancreatic.

Mtengo wapakati wa mankhwalawa umasiyana kuchokera ku 1800 mpaka 2200 rubles.

Kufunika kwa insulin kumatha kuchepa kwambiri pamaso pa kulephera kwa impso. Odwala omwe ali ndi matendawa, kuchuluka kwa mayamwidwe a pancreatic m'thupi kumakhalabe.

Mankhwala

Humalog® ndi DNA yomwe imapangidwanso ndi insulin ya anthu. Amasiyana ndi insulin yaumunthu mu kusintha kwa amino acid m'malo 28 ndi 29 a insulin B.

Mankhwala
Chochita chachikulu cha insulin lyspro ndi malamulo a kagayidwe ka glucose.

Kuphatikiza apo, imakhala ndi anabolic komanso anti-catabolic zotsatira zosiyanasiyana zamthupi. Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa ma amino acid, koma kuchepa kwa glycogenolysis, gluconeogeneis, ketogeneis, ndi lipolysis. catabolism ya protein ndi amino acid kumasulidwa.

Lyspro insulin yawonetsedwa kuti ikufanana ndi insulin yaumunthu, koma zotulukapo zake zimathamanga ndipo zimatha kuchepera. Lyspro insulin imadziwika ndi kuyamba mwachangu (pafupifupi mphindi 15), popeza imakhala ndi kuchuluka kwa mayamwidwe, ndipo izi zimaloleza kuti ziziperekedwa nthawi yomweyo musanadye (0-15 mphindi musanadye), mosiyana ndi insulin yokhazikika (mphindi 30-45) asanadye). Lyspro insulin imatulutsa msanga mphamvu yake ndipo imakhala ndi nthawi yofupikirako (kuyambira maola 2 mpaka 5) poyerekeza ndi insulin yaumunthu.

Odwala omwe ali ndi mtundu woyamba wa 2 ndi mtundu wa 2 shuga, akamagwiritsa ntchito insulin, lyspro hyperglycemia, yomwe imachitika atatha kudya, amachepetsa kwambiri poyerekeza ndi insulin yaumunthu.

Monga momwe akukonzekera insulin yonse, kutalika kwa nthawi ya lyspro insulin kumatha kukhala kosiyanasiyana mwa odwala kapena nthawi zosiyanasiyana wodwala yemweyo ndipo zimatengera mlingo, malo a jakisoni, magazi, kutentha kwa thupi ndi zochitika zolimbitsa thupi.

Makhalidwe a pharmacodynamic a lyspro insulin mwa ana ndi achinyamata ali ofanana ndi amenewo. yomwe imawonedwa mwa akulu.

Kugwiritsa ntchito mankhwala a lyspro insulin mwa odwala omwe ali ndi matenda amtundu wa 2 ndipo amatsatana ndi kuchepa kwa pafupipafupi kwa hypoglycemic nocturnal reaction poyerekeza ndi insulin yaumunthu.

Kuyankha kwa glucodynamic ku lyspro insulin palokha popanda chiwindi kapena impso.

Pharmacokinetics
Pambuyo pothandizidwa ndi subcutaneous, Lyspro insulin imatengedwa mwachangu ndikufika pamatumbo ambiri pambuyo pa mphindi 30-70.

Ndi subcutaneous makonzedwe, theka la moyo wa insulin lispro ili pafupifupi ola limodzi.

Ndi makonzedwe a lyspro insulin, mayamwidwe msanga kuposa sungunuka anthu insulin odwala aimpso kulephera. Odwala omwe ali ndi matenda a shuga a 2, pali kusiyana kwa pharmacokinetic pakati pa lyspro insulin ndi insulle ya munthu insulin, mosasamala kanthu za ntchito yaimpso. Ndi makonzedwe a insulin lyspro, amatha kuyamwa mwachangu komanso kuchotsedwa msanga poyerekeza ndi insulin ya anthu osungunuka ndi chiwindi.

Gwiritsani ntchito panthawi yoyembekezera komanso poyamwitsa

Zambiri pa kugwiritsa ntchito insulin lispro pa nthawi ya pakati zimasonyeza kusapezeka kwa vuto la mankhwalawa pa mimba kapena mkhalidwe wa mwana wosabadwa ndi wakhanda.

Pakati pa nthawi yayitali, chinthu chachikulu ndikukhazikitsa chitetezo chabwino cha glycemic mwa odwala matenda a shuga omwe akulandira chithandizo ndi insulin. Kufunika kwa insulin nthawi zambiri kumachepetsa panthawi yoyambirira ndikuwonjezeka panthawi yachiwiri komanso yachitatu. Nthawi yobadwa pambuyo pokhapokha ndipo mwayamba kubadwa, zofunika za insulin zimatha kugwa kwambiri. Odwala omwe ali ndi matenda ashuga ayenera kukaonana ndi dokotala ngati pakati pachitika kapena akukonzekera. Pankhani ya mimba kwa odwala omwe ali ndi matenda ashuga, chinthu chachikulu ndikuwunika shuga, komanso thanzi lathunthu.

Kwa odwala matenda a shuga nthawi yoyamwitsa, zingakhale zofunikira kusankha kuchuluka kwa insulin, zakudya, kapena zonse ziwiri.

Mlingo ndi makonzedwe

Mlingo wa Humalog® umatsimikiziridwa ndi dokotala aliyense payekha, kutengera kuchuluka kwa shuga m'magazi. Ndondomeko ya insulin makonzedwe ali payekha.

Humalog® imatha kuperekedweratu chakudya chisanafike. Ngati ndi kotheka, Humalog® imatha kuperekedwanso pambuyo chakudya.

Kutentha kwa mankhwala omwe amaperekedwa kuyenera kukhala kutentha kwambiri.

Humalog® iyenera kutumikiridwa ngati jakisoni wofunda kapena ngati kulowetsedwa kofikira pogwiritsa ntchito pampu ya insulin. Ngati ndi kotheka (ketoacidosis, matenda owopsa, nthawi yanthawi yogwira ntchito kapena nthawi yothandizira), kukonzekera kwa Humalog® amathanso kuthandizira.

Subcutaneally ayenera jekeseni phewa, ntchafu, matako kapena m'mimba. Tsambalo la jakisoni liyenera kusinthidwa kuti malo omwewo asagwiritsidwerenso nthawi 1 mwezi uliwonse.

Ndi subcutaneous makonzedwe a Humalog®, chisamaliro chiyenera kutengedwa kuti mankhwalawo asatenge magazi. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Wodwala ayenera kuphunzitsidwa njira yolondola ya jakisoni.

Malangizo a kuperekera mankhwala Humalog®
Kukonzekera mawu oyamba
Njira yothetsera kukonzekera kwa Humalog® iyenera kukhala yowonekera komanso yopanda utoto. Musagwiritse ntchito yankho la Humalog® ngati litakhala lamtambo, lopindika, lopanda utoto, kapena tinthu tating'ono tadziwika.

Mukakhazikitsa cartridge mu syringe cholembera, ndikuyika singano ndi jekeseni wa insulin, tsatirani malangizo a wopanga omwe akuphatikizidwa ndi cholembera chilichonse.

Dose makonzedwe
1. Sambani m'manja.
2. Sankhani tsamba la jakisoni.
3. Konzani khungu lanu jakisoni monga momwe dokotala wanenera.
4. Chotsani kapu yodzitchinjiriza kuchokera singano.
5. Tsekani khungu.
6. Ikani singano pang'onopang'ono ndikuchita jakisoni mogwirizana ndi malangizo ogwiritsa ntchito cholembera.
7. Chotsani singano ndikufinya pang'onopang'ono malo opaka jakisoni ndi swab ya thonje kwa masekondi angapo. Osatupa malo a jakisoni.
8. Pogwiritsa ntchito singano yoteteza kunja, tsekani singano ndikuitaya.
9. Ikani chipewa pa cholembera.

Za kukonzekera kwa Humalog® mu cholembera cha syringe ya QuickPen ™.
Musanapereke insulin, muyenera kuwerenga Malangizo a QuickPen ™ Syringe pen Institions for Use.

Insulinven insulin
Kubayidwa kwapakati pa kukonzekera kwa Humalog® kuyenera kuchitika molingana ndi chizolowezi chachipatala cha jakisoni wamkati, mwachitsanzo, kulowetsedwa kwa bolus kapena kugwiritsa ntchito kulowetsedwa. Poterepa, nthawi zambiri ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi.

Makina a kulowetsedwa okhala ndi zozungulira kuyambira 0,1 IU / ml mpaka 1,0 IU / ml insulin lispro mu 0,9% sodium chloride solution kapena 5% dextrose solution amakhala okhazikika firiji kwa maola 48.

Subcutaneous insulin kulowetsedwa ndi insulin pampu
Potengera kukonzekera kwa Humalog®, mapampu angagwiritsidwe ntchito - makina opitiliza kuperekera insulin ndi chizindikiro cha CE. Musanagwiritse inshuwaransi ya lyspro, onetsetsani kuti pampu ina ndiyabwino. Muyenera kutsatira mosamalitsa malangizo omwe abwera ndi pampu. Gwiritsani ntchito posungira ndi patheter yabwino pampu. The kulowetsedwa anayenera asinthidwe malinga ndi malangizo omwe amaperekedwa ndi kulowetsedwa. Ngati vuto la hypoglycemic litayamba, kulowetsaku kumayimitsidwa mpaka gawo litatsimikiza. Ngati shuga wambiri m'magazi adadziwika, ndikofunikira kudziwitsa adokotala za izi ndikuganizira kuchepetsa kapena kuletsa kulowetsedwa kwa insulin. Kuperewera bwino kwa pampu kapena kufalikira mu dongosolo la kulowetsedwa kungapangitse kukwera kwamphamvu kwa glucose. Ngati mukukayikira kuti akuphwanya insulin, muyenera kutsatira malangizo ndipo ngati kuli koyenera dziwitsani dokotala. Mukamagwiritsa ntchito pampu, kukonzekera kwa Humalog® sikuyenera kusakanikirana ndi ma insulini ena.

Zotsatira zoyipa

Hypoglycemia ndiye chovuta kwambiri pakachitika odwala omwe ali ndi matenda a shuga. Hypoglycemia yayikulu imatha kutha mphamvu ya chikumbumtima (hypoglycemic chikomokere), ndipo, mwatsatanetsatane, kufa.

Odwala amatha kukumana ndi vuto la redness, kutupa, kapena kuyabwa pamalowo. Nthawi zambiri, zizindikirozi zimatha patatha masiku angapo kapena milungu. Nthawi zina, izi zimachitika chifukwa cha zifukwa zosakhudzana ndi insulin, mwachitsanzo, kupsa mtima pakhungu ndi wothandizira kuyeretsa kapena jakisoni wosayenera.

Nthawi zambiri, thupi siligwirizana zimayambira pomwe kuyabwa mthupi, ming'oma, angioedema, kutentha thupi, kufupika, kutsika magazi, tachycardia, ndi thukuta kumachitika. Milandu ingapo yamomwe thupi limagwirira ntchito ikhoza kukhala yowopsa pamoyo.

Lipodystrophy imatha kupezeka pamalo a jakisoni.

Mauthenga wamba:
Milandu ya chitukuko cha edema yadziwika, makamaka ndi kufalikira kwamisempha yamwazi motsutsana ndi maziko a insulini yolimbana ndi vuto loyambirira la glycemic.

Bongo

Mankhwala osokoneza bongo amaphatikizidwa ndi chitukuko cha zizindikiro za hypoglycemia: ulesi, kuchuluka thukuta, njala, kunjenjemera, tachycardia, kupweteka mutu, chizungulire, kusawona bwino, kusanza, chisokonezo.

Magawo ofatsa a hypoglycemic amaletsedwa ndi kumeza shuga kapena zinthu zina zokhala ndi shuga. Kuwongolera kwambiri hypoglycemia angathe kuchitika ntchito mu mnofu kapena subcutaneous makonzedwe a glucagon, kenako ingestion wa chakudya pambuyo kukhazikika kwa mkhalidwe wa wodwalayo. Odwala omwe samalabadira glucagon amapatsidwa njira ya shuga m'mitsempha.

Wodwala akakhala kuti akomoka, ndiye kuti glucagon amayenera kuthandizidwa kudzera mu mnofu kapena mozungulira. Popanda glucagon kapena ngati palibe chochita ndi momwe amayambitsira, ndikofunikira kupaka yankho la dextrose kudzera m'mitsempha. Atangozindikira, wodwalayo ayenera kupatsidwa chakudya chopatsa thanzi.

Kudya zakudya zowonjezera zamagalimoto ndi kuwunika kwa wodwalayo kungafunike, popeza kuyambiranso kwa hypoglycemia ndikotheka.

About hypoglycemia yosamutsidwa ndikofunikira kudziwitsa dokotala.

Kuchita ndi mankhwala ena

Kuopsa kwa zotsatira za hypoglycemic kumachepetsedwa ngati ntchito limodzi ndi mankhwalawa: kulera kwapakamwa, glucocorticosteroids, mahomoni a chithokomiro, danazol, beta2-adrenergic agonists (mwachitsanzo, ribodrin. phenothiazine.

Kuopsa kwa zotsatira za hypoglycemic kumawonjezereka pamodzi ndi mankhwala omwe amaphatikizidwa: beta-blockers, ethanol ndi ethanol-mankhwala, anabolic steroids, fenfluramine. guanethidine, tetracyclines, mankhwala a hypoglycemic a m'kamwa, salicylates (mwachitsanzo acetylsalicylic acid), mankhwala a sulfonamide. antidepressants (monoamine oxidase inhibitors, serotonin reuptake inhibitors), angiotensin kutembenuza enzyme inhibitors (captopril, enapril), octreotide, angiotensin II receptor antagonists.

Ngati mukufunika kugwiritsa ntchito mankhwala ena, kuwonjezera pa insulin, funsani dokotala.

Malangizo apadera

Kusamutsa wodwala kupita ku mtundu wina kapena kukonzekera insulin kuyenera kuchitika moyang'aniridwa ndi achipatala. Kusintha kwa zochitika, mtundu (wopanga), mtundu (Wokhazikika, NPH, ndi zina), mitundu (nyama, munthu, analog ya insulin ya anthu) ndi / kapena njira yopanga (DNA recombinant insulin kapena insulini yachikhalidwe) chitha kubweretsa kufunika kwa kusintha kwa mlingo.

Odwala omwe ali ndi vuto la hypoglycemic atasamutsidwa kuchokera ku insulin yochokera ku nyama kupita ku insulin yaumunthu, zizindikiro zoyambirira za hypoglycemia zitha kutchulidwa pang'ono kapena zosiyana ndi zomwe adakumana nazo kale ndi insulin. Machitidwe osasinthika a hypo- ndi hyperglycemic angapangitse kuti musokonezedwe, chikomokere, kapena kufa.

Tiyenera kukumbukira kuti pharmacodynamics ya analogues ya insulin yogwira ntchito mwachangu ya anthu ndikuti ngati hypoglycemia imayamba, imatha kupanga jakisoni wa insulin wokhala ndi anthu osachedwa kale kuposa vuto la insulin ya anthu.

Kwa odwala omwe amalandira ma insulin achidule komanso oyambira, amafunika kusankha kuchuluka kwa ma insulin onse kuti akwaniritse kuchuluka kwa shuga m'magazi masana, makamaka usiku kapena pamimba yopanda kanthu.

Zizindikiro zakutsogolo kwa hypoglycemia zimatha kusintha ndikusatchulidwa pang'ono ndi njira yayitali ya matenda a shuga, matenda ashuga a m'mimba kapena chithandizo cha mankhwala monga beta-blockers.

Mlingo wosakwanira kapena kusiya kulandira chithandizo, makamaka kwa odwala omwe ali ndi matenda a shuga 1, angayambitse matenda a hyperglycemia ndi matenda ashuga - matenda omwe angawononge odwala.

Kufunika kwa insulin kumatha kuchepa ngati kulephera kwa impso, komanso kwa odwala omwe ali ndi vuto la kuchepa kwa chiwindi chifukwa cha kuchepa kwa njira ya gluconeogeneis ndi insulin metabolism. Komabe, mwa odwala omwe ali ndi vuto losatha la chiwindi, kuchuluka kwa insulin kungayambitse kuchuluka kwa insulin.

Kufunika kwa insulin kumatha kuwonjezeka ndi matenda ena kapena kupsinjika mtima.

Malangizo a insulin ayenera kuchuluka ngati odwala akuwonjezera zolimbitsa thupi kapena akusintha zakudya zamagulu. Kuchita masewera olimbitsa thupi kumatha kuyambitsa chiwopsezo cha hypoglycemia.

Mukamagwiritsa ntchito insulin pokonzekera limodzi ndi mankhwala a gulu la thiazolidinedione, chiopsezo chotenga matenda a edema ndi matenda a mtima omwe amalephera chikuwonjezereka, makamaka kwa odwala omwe ali ndi matenda amtima komanso kupezeka kwa zinthu zomwe zingayambitse matenda osalephera a mtima.

Kugwiritsa ntchito Humalog® kwa ana m'malo mwa insulin yaumunthu yosungunuka ndikofunikira panthawi ngati kuli koyenera kuyambitsa mwachangu insulin (mwachitsanzo, kuyambitsa insulini musanadye).

Popewa kufalitsa matenda opatsirana, cholembera / cholembera chilichonse chimayenera kugwiritsidwa ntchito ndi wodwala m'modzi, ngakhale singano isinthidwe.

Ma cartridge a Humalog® ayenera kugwiritsidwa ntchito ndi ma syringes omwe ali ndi chizindikilo cha CE malinga ndi malangizo a wopanga chipangizocho.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Panthawi ya hypoglycemia, chidwi ndi kuthamanga kwa zochitika zama psychomotor zimatha kuchepa. Izi zitha kukhala zowopsa nthawi zomwe maluso amenewa amafunikira makamaka (mwachitsanzo, kuyendetsa magalimoto kapena makina ogwiritsa ntchito).

Odwala ayenera kulangizidwa kuti azisamala kuti asawonongeke poyendetsa galimoto poyendetsa magalimoto ndi makina owongolera. Izi ndizofunikira kwambiri kwa odwala omwe ali ndi zofatsa kapena zosapezekapo zizindikiro, okhazikika a hypoglycemia kapena okhazikika a hypoglycemia. Zikatero, adotolo amayenera kuwunika momwe magalimoto amayendera odwala.

Kutulutsa Fomu

Yothetsera kudzera mu mtsempha wa magazi a 100 IU / ml mu makilogalamu atatu.

Makatoni:
3 ml ya mankhwala pa cartridge. Makatiriji asanu pachimake. Chithuza chimodzi pamodzi ndi malangizo ogwiritsira ntchito pakatoni.
Kuphatikiza apo, pankhani yokhazikitsa mankhwalawo ku kampani ya Russia OPTAT, JSC, chomata choyambirira chotsegulira chimayikidwa.

QuickPen ™ Syringe Pens:
3 ml ya mankhwalawa mu cartridge wophatikizidwa ndi cholembera cha syringe ya QuickPen ™. Ma syringe asanu a QuickPen ™, iliyonse ili ndi malangizo ogwiritsa ntchito ndi cholembera cha syringe ya QuickPEN ™ mu bokosi la makatoni.
Kuphatikiza apo, pankhani yokhazikitsa mankhwalawo ku kampani ya Russia OPTAT, JSC, chomata choyambirira chotsegulira chimayikidwa.

Malangizo achidule

Malangizo ogwiritsira ntchito insulin Humalog ndiwosakhazikika, ndipo magawo omwe amafotokoza zoyipa ndi mayendedwe akugwiritsidwa ntchito amakhala ndi zigawo zingapo.

Kufotokozera kwakutali komwe kumayendera limodzi ndimankhwala ena kumadziwika ndi odwala ngati chenjezo lokhuza kuwopsa kwawo.

M'malo mwake, zonse ndizofanana: langizo lalikulu, latsatanetsatane - umboni wa mayesero ambirikuti mankhwalawa adapirira.

Humalogue wavomerezedwa kuti agwiritse ntchito zaka 20 zapitazo, tsopano titha kunena motsimikiza kuti insuliniyi ndiyotetezeka pa mlingo woyenera.Imavomerezedwa kuti agwiritsidwe ntchito ndi akulu ndi ana onse;

Zambiri pa Humalogue:

Zina mwazotsatira zoyipa, hypoglycemia ndi thupi lawo siligwirizana nthawi zambiri zimawonedwa (1-10% ya odwala matenda ashuga). Osakwana 1% odwala amakhala ndi lipodystrophy pamalo opangira jekeseni. Makulidwe azinthu zina zoyipa amakhala ochepera 0.1%.

Chofunika Kwambiri Zokhudza Humalog

Kunyumba, Humalog imayendetsedwa pang'onopang'ono pogwiritsa ntchito cholembera kapena pampu ya insulin. Ngati matenda oopsa a hyperglycemia atachotsedwa, mankhwala osokoneza bongo amathandizanso kuchipatala. Pankhaniyi, kuthana ndi shuga pafupipafupi ndikofunikira kupewa bongo.

Chithandizo chogwira ntchito cha mankhwala ndi insulin lispro. Amasiyana ndi mahomoni amunthu pakupanga ma amino acid mu molekyulu. Kusintha koteroko sikulepheretsa ma cell receptors kuzindikira mahomoni, chifukwa chake amapatsira shuga mwa iwo okha.

Chiwonetserochi chimakhala ndi ma insulin monomers okha - mamolekyulu osalumikizana. Chifukwa cha izi, imakamizidwa mwachangu komanso moyenera, imayamba kugwira ntchito kuti muchepetse shuga mwachangu kuposa insulin yachilendo.

Humalog ndi mankhwala ofupikitsika kuposa, mwachitsanzo, Humulin kapena Actrapid. Malinga ndi gulu, amatchulidwa ndi ma insulin omwe ali ndi ultrashort action.

Kuyamba kwa ntchito yake kumachitika mwachangu, pafupifupi mphindi 15, kotero odwala matenda ashuga sayenera kudikirira mpaka mankhwalawo atagwira, koma mutha kukonzekera chakudya mukangobaya jakisoni.

Chifukwa cha kufupika kwakanthawi, kumakhala kosavuta kukonza zakudya, ndipo chiopsezo cha kuiwala chakudya jakisoni itachepa.

Kuti muthane ndi vuto labwino la glycemic, insulin yothamanga imayenera kuphatikizidwa ndi kuvomerezedwa kwa insulin yayitali. Chokha chosiyana ndi kugwiritsa ntchito pampu ya insulin nthawi zonse.

Malo osungira

Sungani mufiriji kutentha kwa 2-8 ° C.
Mankhwala ogwiritsira ntchito katiriji / syringe ayenera kusungidwa kutentha kwambiri osapitirira 30 ° C osapitirira masiku 28.
Kuteteza ku dzuwa mwachindunji ndi kutentha. Osalola kuzizira.
Pewani kufikira ana.

Sankhani

Mlingo wa Humalog umatengera zinthu zambiri ndipo umatsimikiziridwa payekhapayekha kwa aliyense wodwala matenda ashuga. Kugwiritsa ntchito njira zoyenera sikulimbikitsidwa, popeza zimakulitsa kubwezeretsanso shuga.

Ngati wodwala amatsatira zakudya zamafuta ochepa, mlingo wa Humalog umakhala wocheperako kuposa momwe oyang'anira angapangire. Pankhaniyi, tikulimbikitsidwa kugwiritsa ntchito insulin yofulumira.

Ndikofunikira kwambiri: Lekani kudyetsa mafia azakudya zonse. Ma Endocrinologists amatipangitsa kuti tiziwonongeratu ndalama pamapiritsi pomwe shuga m'magazi amatha kukhala ngati ma ruble 147 ... >> werengani nkhani ya Alla Viktorovna

Hormashort ya Ultrashort imapereka mphamvu kwambiri. Mukasinthira ku Humalog, mlingo wake woyambirira amawerengedwa ngati 40% ya insulin yayifupi. Malinga ndi zotsatira za glycemia, mlingo umasinthidwa. Chofunikira pakukonzekera mkate uliwonse ndimagawo 1-1,5.

Mayina ndi maadiresi amalo opanga

Kupanga kwa fomu yomalizira Mlingo ndi ma CD oyambira:
"Lilly France." France (cartridgeges, QuickPen ™ syringe pensulo)
2 Ru du Colonel Lilly, 67640 Fegersheim, France

Kukhazikitsa kwachiwiri ndikupereka mawonekedwe oyang'anira:
Lilly France, France
2 Ru du Colonel Lilly, 67640 Fegersheim
kapena
Eli Lilly ndi Company, USA
Indianapolis, Indiana. 46285 (QuickPen ™ Syringe Pens)
kapena
JSC OPTAT, Russia
157092, dera la Kostroma, chigawo cha Susaninsky, ndi. Kumpoto, microdistrict. Kharitonovo

Ndondomeko ya jekeseni

Chakudya chimayalidwa chakudya chilichonse chisanachitike. osachepera katatu patsiku. Pankhani ya shuga wambiri, mawonekedwe okhathamira pakati pa jakisoni wamkulu amaloledwa. Malangizo ogwiritsira ntchito akutsimikizira kuwerengera kuchuluka kwa insulini yochokera pamafuta omwe akukonzekera chakudya chotsatira. Pafupifupi mphindi 15 ayenera kuchokera jakisoni kupita chakudya.

Malinga ndi ndemanga, nthawi ino nthawi zambiri zimakhala zochepa, makamaka masana, pomwe insulin kukana imakhala yotsika. Mlingo wa mayamwidwe ndi munthu payekhapayekha, umatha kuwerengeka pogwiritsa ntchito kuchuluka kwa shuga m'magazi pambuyo pobayidwa. Ngati kutsitsa kwa shuga kumawonedwa mwachangu kuposa momwe malangizowo amafunikira, nthawi yomwe chakudya chisanachitike iyenera kuchepetsedwa.

Humalog ndi imodzi mwamankhwala omwe amafulumira kwambiri, chifukwa chake nchosavuta kugwiritsa ntchito ngati thandizo ladzidzidzi kwa matenda ashuga ngati wodwala akuwopseza kuti ali ndi vuto la hyperglycemic.

Chonde werengani Malangizo a QuickPen ™ Syringe pen Malangizo Ogwiritsira Ntchito Musanagwiritse Ntchito

Werengani bukuli musanayambe kugwiritsa ntchito insulin koyamba. Nthawi iliyonse mukalandira phukusi latsopano ndi zolembera za syPinge za QuickPen, muyenera kuwerenga malangizo kuti mugwiritsirenso, monga ikhoza kukhala ndi zidziwitso zosinthidwa. Chidziwitso chomwe chili m'malangizowa sichimachotsa zokambirana ndi dokotala wanu za matendawo ndi chithandizo chanu.

Chikwangwani cha QuickPen ™ Syringe cholembera ("Syringe pen") ndi cholembera chomwe sichitha, chomwe chili ndi mayunitsi 300 a insulini. Ndi cholembera chimodzi, mutha kupereka ma insulin angapo. Pogwiritsa ntchito cholembera ichi, mutha kulowa muyezo ndi chidziwitso cha 1 unit. Mutha kulowa kuchokera pa 1 mpaka 60 mayunitsi paliponse. Ngati mlingo wanu uposa mayunitsi 60, muyenera kuchita jakisoni wambiri. Ndi jakisoni aliyense, pisitoni imangoyenda pang'ono, ndipo mwina simungathe kuwona kusintha kwake. Piston imafika pansi pa cartridge pokhapokha mutagwiritsa ntchito zigawo zonse 300 zomwe zili mu cholembera.

Cholembera sichitha kugawidwa ndi anthu ena, ngakhale mutagwiritsa ntchito singano yatsopano. Osagwiritsanso ntchito singano. Osadutsa singano kwa anthu ena. Matenda atha kupatsirana ndi singano, zomwe zingayambitse matenda.

Sitikulimbikitsidwa kuti mugwiritse ntchito kwa odwala omwe ali ndi vuto la kuwona kapena kutayika kwathunthu popanda kuthandizidwa ndi anthu owona bwino ophunzitsidwa bwino kugwiritsa ntchito cholembera.

Nthawi yogwira (yochepa kapena yayitali)

Peak ya insulin ya ultrashort imawonedwa patatha mphindi 60 kuchokera pakukhazikitsa. Kutalika kwa zochita zimatengera mlingo; kukula kwake ndikutalika kwa shuga, pafupifupi - pafupifupi maola 4.

Kusakaniza kwa Humalog 25

Kuti muwone molondola momwe Humalog ikuyendera, shuga ayenera kuyesedwa pambuyo pa nthawi imeneyi, nthawi zambiri izi zimachitika chakudya chisanafike. Miyeso yoyambirira imafunikira ngati hypoglycemia ikukayikira.

Kutalika kwakanthawi kwa Humalog si koyipa, koma mwayi wa mankhwalawa. Tikuthokoza, odwala omwe ali ndi matenda osokoneza bongo sakhala ndi vuto la hypoglycemia, makamaka usiku.

Kusakaniza Kwa Humalog

Kuphatikiza pa Humalog, kampani yopanga zamankhwala Lilly France imatulutsa Humalog Remix. Ndiosakanikirana kwa lyspro insulin ndi protamine sulfate. Chifukwa cha kuphatikiza uku, nthawi yoyambira ya mahomoni imakhalabe mwachangu, ndipo nthawi yochitapo kanthu imawonjezeka kwambiri.

Kusintha kwa Humalog kumapezeka mu 2indi:

Ubwino wokhawo wa mankhwalawa ndi regimen yosavuta. Kulipira shuga kwa odwala matenda ashuga ndi kagwiritsidwe ntchito kwawo ndi koipa kuposa kukhala ndi mankhwalawa a insulin komanso kugwiritsa ntchito mtundu wina wa Humalog ana Humalog Mix sagwiritsidwa ntchito.

Insulin iyi imayikidwa:

1. Anthu odwala matenda ashuga omwe sangathe kuwerengera payekha payekha kapena kupanga jakisoni, mwachitsanzo, chifukwa cha kusawona bwino, ziwalo kapena kugwedezeka.
2. Odwala omwe ali ndi matenda amisala.
3. Okalamba okalamba omwe ali ndi zovuta zambiri za matenda a shuga komanso kuperewera koyipa kwa chithandizo ngati safuna kuphunzira malamulo owerengera insulin.
4. Anthu odwala matenda ashuga omwe ali ndi matenda amtundu wa 2, ngati mahomoni awo akupangidwabe.

Ma Analogi a Humalog

Lyspro insulin monga chinthu chogwira imangopezeka mu Humalog yoyambayo. Mankhwala osokoneza bongo ndi NovoRapid (kutengera aspart) ndi Apidra (glulisin).

Zida izi ndizoperewera -fupi, choncho zilibe kanthu kuti muzisankha iti. Zonse zimalekeredwa bwino ndipo zimapereka shuga msanga.

Monga lamulo, zokonda zimaperekedwa kwa mankhwalawa, omwe amatha kupezeka kwaulere kuchipatala.

Kusintha kuchokera ku Humalog kupita ku analogue yake kungakhale kofunikira pakakhala zovuta zina. Ngati wodwala matenda ashuga amatsatira zakudya zamafuta ochepa, kapena amakhala ndi hypoglycemia, ndizosavuta kugwiritsa ntchito anthu m'malo mwa insulin.

Chonde dziwani: Kodi mumalota kuti muthetse matenda ashuga kamodzi? Phunzirani momwe mungathetsere matendawa, osagwiritsa ntchito mankhwala okwera mtengo pokhapokha ... >> werengani zambiri apa

Fotokozerani zokambirana ku Yandex.Health. Pakupita mphindi 5, dokotala angakuthandizeni kuzindikira
ndi contraindication payekha, Mlingo ndi mavuto.

Yankho la iv and sc management zowonekera, zopanda utoto.

Othandizira: glycerol (glycerin) - 16 mg, metacresol - 3,15 mg, zinc oxide - q.s. pazambiri za Zn2 + 0.0197 mg, sodium hydrogen phosphate heptahydrate - 1.88 mg, hydrochloric acid, yankho la 10% ndi / kapena sodium hydroxide solution 10% - q.s. mpaka pH 7.0-8.0, madzi d / i - q.s. mpaka 1 ml.

3 ml - makatoni (5) - matuza (1) - phukusi la makatoni.
3 ml - makatoni omwe adapangidwa mu cholembera cha syringe cha QuickPen (5) - makatoni.

DNA imabweretsanso insulin. Amasiyana ndi omaliza mwanjira zotsatizana za amino acid pamalo 28 ndi 29 a insulin B.

Choyambitsa chachikulu cha mankhwalawa ndi kuyamwa kwa kagayidwe kazakudya. Kuphatikiza apo, ili ndi anabolic zotsatira.

Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa ma amino acid, koma nthawi yomweyo kumachepa mu glycogenolysis, gluconeogeneis, ketogeneis, lipolysis, proteinabolism ndi kutulutsidwa kwa ma amino acid.

Odwala omwe ali ndi mtundu woyamba wa 2 ndi mtundu wa 2 shuga, akamagwiritsa ntchito insulin lyspro, hyperglycemia yomwe imachitika chakudya itatha amachepetsa kwambiri poyerekeza ndi insulin yaumunthu. Kwa odwala omwe amalandira ma insulin achidule komanso ofunika, amafunika kusankha kuchuluka kwa ma insulin onse kuti tsiku lililonse azikhala ndi shuga.

Monga momwe akukonzekera insulin yonse, kutalika kwa nthawi ya lyspro insulin kumatha kukhala kosiyanasiyana mwa odwala kapena nthawi zosiyanasiyana wodwala yemweyo ndipo zimatengera mlingo, malo a jakisoni, magazi, kutentha kwa thupi ndi zochitika zolimbitsa thupi.

Mankhwala a lyspro insulin mwa ana ndi achinyamata ali ofanana ndi omwe amawonekera mwa akulu.

Odwala omwe ali ndi matenda a shuga a 2 omwe amalandila Mlingo wambiri wa sulfonylurea, kuwonjezera kwa insulin kumabweretsa kuchepa kwakukulu kwa hemoglobin wa glycated.

Mankhwala a Lyspro insulin kwa odwala omwe ali ndi matenda amtundu wa 2 ndi mtundu wa 2 amaphatikizidwa ndi kuchepa kwa ziwonetsero za nocturnal hypoglycemia.

Kuyankha kwa glucodynamic ku isulin lispro sikudalira kugwira ntchito kwa impso kapena chiwindi.

Zinawonetsedwa kuti insulin lyspro imakhala yofanana ndi insulin yaumunthu, koma zochita zake zimachitika mwachangu ndipo zimatha kwakanthawi.

Lyspro insulin imadziwika ndi kuyamba mwachangu (pafupifupi mphindi 15), monga

Ili ndi mayamwidwe ambiri, ndipo izi zimakupatsani mwayi woti mulowe musanadye (0-15 mphindi musanadye), mosiyana ndi insulin yachilendo (mphindi 30-45 musanadye).

Lyspro insulin imakhala ndi nthawi yofupikirako (maola 2 mpaka 5) poyerekeza ndi insulin yaumunthu wamba.

Zogulitsa ndi kugawa

Pambuyo pakuyang'anira sc, insulin Lyspro imatengedwa mwachangu ndikufika ku Cmax m'madzi a m'magazi pambuyo pa mphindi 30-70. Vd ya insulin lyspro ndi insulin wamba ya anthu ndi ofanana ndipo ali mgulu la 0.26-0.36 l / kg.

Ndi sc makonzedwe a T1 / 2 a insulin, lyspro ili pafupifupi ola 1. Odwala omwe ali ndi impso ndi hepatic insufficiency amakhala ndi kuchuluka kwa mayamwidwe a lyspro insulin poyerekeza ndi masiku onse a insulin.

- shuga mellitus mwa akulu ndi ana, omwe amafunikira chithandizo cha insulin kuti akhalebe ndi shuga.

Dokotala amatsimikiza za mankhwalawo payekha, kutengera zosowa za wodwalayo. Humalog® imatha kuperekedweratu chakudya chisanafike, ngati kuli kofunikira mukangomaliza kudya.

Kutentha kwa mankhwala omwe amaperekedwa kuyenera kukhala kutentha kwambiri.

Humalog® imayendetsedwa s / c ngati jakisoni kapena ngati kulowetsedwa kwa s / c pogwiritsa ntchito pampu ya insulin.Ngati ndi kotheka (ketoacidosis, matenda owopsa, nthawi pakati pa ntchito kapena nthawi ya postoperative) Humalog® ikhoza kutumikiridwa iv.

SC iyenera kuperekedwa kwa phewa, ntchafu, matako, kapena pamimba. Masamba a jakisoni ayenera kusinthidwa kuti malo omwewo asagwiritsidwerenso nthawi 1 pamwezi.

Mukamayambitsa mankhwala a Humalog®, mankhwalawa ayenera kuthandizidwa kuti mankhwalawo asatenge magazi. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa.

Wodwala ayenera kuphunzitsidwa njira yolondola ya jakisoni.

Malangizo a kukhazikitsidwa kwa mankhwalawa Humalog®

Kukonzekera mawu oyamba

Mankhwala osokoneza bongo a Humalog® ayenera kukhala owonekera komanso opanda khungu. Njira yothira ngati yafinya, kapena yakuwala pang'ono ya mankhwalawo, kapena ngati tinthu tating'onoting'ono tapezeka m'maso, sitiyenera kugwiritsidwa ntchito.

Mukakhazikitsa cartridge mu syringe cholembera (cholembera), ndikulowa ndi singano ndikuchita jakisoni wa insulin, ndikofunikira kutsatira malangizo a wopanga omwe amaphatikizidwa ndi cholembera chilichonse.

2. Sankhani tsamba la jakisoni.

3. Antiseptic kuchitira khungu malo jakisoni.

4. Chotsani kapu ku singano.

5. Sinthani khungu lanu mwakuutambasula kapena poteteza khola lalikulu. Ikani singano molingana ndi malangizo ogwiritsa ntchito cholembera.

6. Kanikizani batani.

7. Chotsani singano ndikufinya pang'onopang'ono malo a jakisoni kwa masekondi angapo. Osatupa malo a jakisoni.

8. Pogwiritsa ntchito singano, inaninso singano ndikuwononga.

9. Mawebusayiti ayenera kusinthidwa kuti malo omwewo asagwiritsenso ntchito nthawi 1 pamwezi.

I kuyang'anira insulin

Kubayidwa kwapakati pa kukonzekera kwa Humalog® kuyenera kuchitika molingana ndi chizolowezi chachipatala cha jakisoni wamkati, mwachitsanzo, kulowetsedwa kwa bolus kapena kugwiritsa ntchito kulowetsedwa. Poterepa, nthawi zambiri ndikofunikira kulamula kuchuluka kwa shuga m'magazi.

Makina a kulowetsedwa okhala ndi zozungulira kuyambira 0,1 IU / ml mpaka 1,0 IU / ml insulin lispro mu 0,9% sodium chloride solution kapena 5% dextrose solution amakhala okhazikika firiji kwa maola 48.

Kulowetsedwa kwa insulin / P / C pogwiritsa ntchito pampu ya insulin

Potengera kulowetsedwa kwa Humalog®, mapampu Ochepera ndi Disetronic angagwiritsidwe ntchito kulowetsedwa kwa insulin. Muyenera kutsatira mosamalitsa malangizo omwe abwera ndi pampu. Njira ya kulowetsedwa imasinthidwa maola 48 aliwonse.

Pakachitika vuto la hypoglycemic, kulowetsaku kumayimitsidwa mpaka gawo litatsimikiza. Ngati pali shuga wobwereza mobwerezabwereza kapena wochepa kwambiri m'magazi, ndiye kuti muyenera kudziwitsa dokotala za izi ndikuganiza kuchepetsa kapena kuletsa kulowetsedwa kwa insulin.

Kuperewera kwa pampu kapena kufalikira mu dongosolo la kulowetsedwa kumatha kubweretsa kukwera msanga kwamagazi. Ngati mukukayikira kuti akuphwanya insulin, muyenera kutsatira malangizowo ndipo ngati kuli koyenera dziwitsani adokotala.

Mukamagwiritsa ntchito pampu, kukonzekera kwa Humalog® sikuyenera kusakanikirana ndi ma insulini ena.

Zotsatira zoyipa zomwe zimapezeka ndi mankhwala: hypoglycemia. Hypoglycemia yayikulu imatha kutha mphamvu ya chikumbumtima (hypoglycemic chikomokere), ndipo, mwatsatanetsatane, kufa.

Zotsatira zoyipa: thupi lawo siligwirizana angathe - redness, kutupa kapena kuyabwa pa jakisoni jekeseni (nthawi zambiri zimatha patadutsa masiku angapo kapena masabata), zokhudza zonse zomwe zimachitika (zimachitika kangapo, koma zimakhala zowopsa) - kuyabwa kwambiri, urticaria, angioedema, kutentha thupi, kufupika, kuchepa HELL, tachycardia, kuchuluka thukuta. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pachiwopsezo cha moyo.

Zomwe zimachitika: lipodystrophy pamalo a jekeseni.

- Hypersensitivity ku zigawo za mankhwala.

Mpaka pano, palibe zotsatira zosasangalatsa za Lyspro insulin pa mimba kapena thanzi la mwana wosabadwayo / wakhanda. Palibe kafukufuku wokhudzana ndi mliri omwe adachitika.

Cholinga cha mankhwala a insulin panthawi yapakati ndikusunga chiwonetsero chokwanira cha kuchuluka kwa shuga mwa odwala omwe ali ndi matenda a shuga a shuga komanso omwe ali ndi matenda a shuga. Kufunika kwa insulin nthawi zambiri kumachepera mu trimester yoyamba ndikuwonjezeka muyezo wachiwiri ndi wachitatu wama trimesters apakati. Nthawi yobadwa pambuyo pokhapokha ndipo mwayamba kubadwa, zofunika za insulin zimatha kugwa kwambiri.

Akazi azaka zaubalaAnthu omwe ali ndi matenda ashuga ayenera kudziwitsa dokotala za mimba yomwe akukonzekera kapena yomwe ikukonzekera. Pa nthawi yoyembekezera, odwala matenda a shuga amafunika kuwunika mosamala kuchuluka kwa shuga m'magazi, komanso kuyang'aniridwa kawirikawiri kuchipatala.

Odwala omwe ali ndi matenda a shuga mellitus nthawi yoyamwitsa, kusintha kwa insulin ndi / kapena zakudya kungafunike.

Kufunika kwa insulin kumatha kuchepa ndi vuto la chiwindi.

Odwala omwe ali ndi hepatic insufficiency, kuchuluka kwa mayamwidwe a lyspro insulin kumakhalabe kuyerekezera ndi wamba insulin.

Kufunika kwa insulin kumatha kuchepa ndi kulephera kwa aimpso.

Odwala omwe amalephera kupweteka kwa impso, chiwopsezo chambiri cha lyspro insulin chimasungidwa poyerekeza ndi insulin yaumunthu.

Kusamutsa wodwala kupita ku mtundu wina kapena mtundu wa insulin kuyenera kuchitika moyang'aniridwa ndi achipatala.

Kusintha kwa zochitika, mtundu (wopanga), mtundu (mwachizolowezi, NPH, Tape), mitundu (nyama, anthu, ma insulin analogue) ndi / kapena njira yopanga (kubwerezanso DNA insulin kapena insulin ya nyama) kungafunike kusintha kwa mlingo.

Mikhalidwe yomwe zizindikiro zoyambirira za hypoglycemia zitha kukhala zopanda tanthauzo komanso zocheperako zimaphatikizira matenda a shuga, kupatsirana kwa insulin, matenda amanjenje matenda a shuga, kapena mankhwala, monga beta-blockers.

Odwala omwe ali ndi vuto la hypoglycemic atasamutsidwa kuchokera ku insulin yochokera ku nyama kupita ku insulin yaumunthu, zizindikiro zoyambirira za hypoglycemia zitha kutchulidwa pang'ono kapena zosiyana ndi zomwe adakumana nazo kale ndi insulin. Hypoglycemic yosasinthika kapena ma hyperglycemic zomwe zimachitika zimatha kuyambitsa chikumbumtima, chikomokere, kapena kufa.

Mlingo wosakwanira kapena kusiya kulandira chithandizo, makamaka ndi matenda a shuga a shuga.

Kufunika kwa insulin kumatha kuchepa kwa odwala omwe amalephera kupweteka kwa impso, komanso kwa odwala omwe ali ndi vuto la chiwindi chifukwa kuchepa kwa gluconeogeneis ndi insulin metabolism. Komabe, mwa odwala omwe ali ndi vuto losatha la chiwindi, kukana kwa insulini kungayambitse kuchuluka kwa insulin.

Kufunika kwa insulin kumatha kuwonjezeka ndi matenda opatsirana, kupsinjika kwamalingaliro, ndikuwonjezereka kwa kuchuluka kwa chakudya chamagulu muzakudya.

Kusintha kwa mlingo kungafunikenso ngati wodwala akucita zolimbitsa thupi kapena ngati zakudya zabwinobwino zasintha.

Kuchita masewera olimbitsa thupi mukangomaliza kudya kumawonjezera chiopsezo cha hypoglycemia.

Zotsatira za pharmacodynamics za insulin analogi zomwe zimagwira mwachangu ndikuti ngati hypoglycemia imayamba, ndiye kuti imatha kupanga jekeseni m'mbuyomu kuposa kubayidwa insulin yamunthu.

Wodwalayo ayenera kuchenjezedwa kuti ngati dokotala atayambitsa kukonzekera kwa insulin ndi kuchuluka kwa 40 IU / ml mu vial, ndiye kuti insulini sayenera kutengedwa kuchokera ku cartridge ndi insulin ya 100 IU / ml ndi syringe ya jekeseni wa insulin wochita ndi 40 IU / ml.

Ngati pakufunika kumwa mankhwala ena nthawi imodzi ndi Humalog®, wodwalayo ayenera kufunsa dokotala.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Ndi hypoglycemia kapena hyperglycemia yolumikizana ndi mtundu wosakwanira wa dosing, kuphwanya kuthekera kwambiri komanso kuthamanga kwa zochitika zama psychomotor ndikotheka. Izi zitha kukhala pachiwopsezo cha zinthu zoopsa (kuphatikizapo kuyendetsa galimoto kapena kugwira ntchito ndi makina).

Odwala ayenera kusamala kuti apewe hypolycemia poyendetsa. Izi ndizofunikira kwambiri kwa odwala omwe ali ndi kuchepetsedwa kapena kusamvetseka kwa zizindikiro zoneneratu za hypoglycemia, kapena omwe zochitika za hypoglycemia ndizofala.

Pazochitika izi, ndikofunikira kuyesa kuwongolera kutha kuyendetsa. Odwala omwe ali ndi matenda ashuga amatha kudzithandizira kuti amvetsetse Hypoglycemia wodwala ngati atenga glucose kapena zakudya zamafuta ambiri (tikulimbikitsidwa kuti nthawi zonse mumakhala ndi shuga g 20%).

Wodwala ayenera kudziwitsa adokotala za hypoglycemia yomwe idasamutsidwa.

Zizindikiro hypoglycemia, limodzi ndi zizindikiro zotsatirazi: ulesi, kuchuluka thukuta, tachycardia, mutu, kusanza, chisokonezo.

Chithandizo: Hypoglycemia yofewa nthawi zambiri imayimitsidwa ndi kulowerera kwa shuga kapena shuga wina, kapena zinthu zomwe zimakhala ndi shuga.

Kuwongolera kwa hypoglycemia moyenera kumatha kuchitika mothandizidwa ndi / m kapena s / c kukhudzana ndi glucagon, kenako kutsekeka kwa chakudya chamagulu pambuyo pakhazikika pakudwala. Odwala omwe samalabadira glucagon amapatsidwa njira ya iv dextrose (glucose).

Wodwala akakhala kuti akomoka, ndiye kuti glucagon uyenera kutumikiridwa / m kapena s / c. Pokhapokha glucagon kapena ngati palibe chochita ndi kayendetsedwe kake, ndikofunikira kuyambitsa yankho la dextrose (glucose). Atangozindikira, wodwalayo ayenera kupatsidwa chakudya chopatsa thanzi.

Zakudya zowonjezera zowonjezera zamafuta othandizira ndikuwunikira odwala zingafunike, popeza kuyambiranso kwa hypoglycemia ndikotheka.

Mphamvu ya Humalog's hypoglycemic imachepetsedwa ndi kulera kwapakamwa, corticosteroids, kukonzekera kwa mahomoni a chithokomiro, danazol, beta2-adrenergic agonists (kuphatikizapo rhytodrin, salbutamol, terbutaline), tricyclic antidepressants, thiazide diuretics, chlorprotixen, diazitumum zotumphukira za phenothiazine.

Zotsatira za hypoglycemic za Humalog zimapangidwira ndi ophatikiza ndi beta, ma ethanol ndi mankhwala okhala ndi ethanol, anabolic steroids, fenfluramine, guanethidine, tetracyclines, mankhwala apakamwa a hypoglycemic, salicylates (mwachitsanzo, acetylsalicylic acid, aniloprilactyl antagonists, MAP inhibitors, angiotensin II zolandila.

Humalog® sayenera kusakanikirana ndi kukonzekera kwa insulin ya nyama.

Humalog ® ikhoza kugwiritsidwa ntchito (kuyang'aniridwa ndi dokotala) kuphatikiza ndi insulin yayitali yaumunthu, kapena kuphatikiza ndi omwa a hypoglycemic othandizira, zotumphukira za sulfonylurea.

Mndandanda B. Mankhwalawa amayenera kusungidwa kuti ana asawafikire, mufiriji, kutentha kwa 2 ° mpaka 8 ° C, osazizira. Moyo wa alumali ndi zaka 2.

Mankhwala omwe amagwiritsidwa ntchito akuyenera kusungidwa kutentha 15th mpaka 25 ° C, otetezedwa ku dzuwa kapena kutentha mwachindunji Moyo wa alumali - osaposa masiku 28.

Mankhwala ndi mankhwala.

Chidziwitso cha sayansi chomwe chaperekedwa ndiwofananizidwa ndipo sichingagwiritsidwe ntchito kusankha pazomwe angagwiritse ntchito mankhwala.

Pali ma contraindication, funsani dokotala.

Makhalidwe ndi malangizo ogwiritsira ntchito insulin Humalog

Mwa zina mwa mankhwala omwe amapezeka ndi insulin ambiri amatha kutchedwa Humalog. Mankhwala akupangidwa ku Switzerland.

Zimakhazikitsidwa ndi insulin Lizpro ndipo cholinga chake ndikuchizira matenda ashuga.

Mankhwala ayenera kuikidwa ndi dokotala. Ayeneranso kufotokozera malamulo omwera mankhwalawo kuti mupewe mavuto. Mankhwalawa amagulitsidwa kokha ndi mankhwala.

Zambiri ndi mankhwala a pharmacological

Humalog ili mu mawonekedwe a kuyimitsidwa kapena jakisoni. Kuyimitsidwa kumakhala koyera komanso kutengera kupangika. Njira yothetsera vutoli ndi yopanda utoto komanso wopanda fungo, yowonekera.

Chofunikira kwambiri pakuphatikizidwa ndi Lizpro insulin.

Kuphatikiza apo, zosakaniza monga:

• madzi
• metacresol
• zinc oxide
• glycerol
• sodium hydrogen phosphate heptahydrate,
• sodium hydroxide solution.

Chogulitsachi chimagulitsidwa m'mak cartridge atatu. Makatoni ali mu cholembera cha Quickpen, zidutswa 5 pa paketi imodzi.

Komanso pali mitundu ya mankhwalawa, yomwe imaphatikizapo yankho laling'ono la insulin komanso kuyimitsidwa kwa protamine. Amadziwika kuti Humalog Remix 25 ndi Humalog Remix 50.

Lizpro insulin ndi mawonekedwe a insulin yaumunthu ndipo amadziwika ndi zomwezi. Zimathandizira kukulitsa kuchuluka kwa shuga. Pulogalamu yogwira imagwira pama cell membrane, chifukwa chomwe shuga kuchokera m'magazi amalowera minofu ndikugawikidwamo. Zimathandizanso kupanga mapuloteni omwe amagwira ntchito.

Mankhwala amadziwika ndi kuchitapo kanthu mwachangu. Zotsatira zimawonekera mkati mwa kotala la ola mutatha jakisoni. Koma imapitilira kwakanthawi. Hafu ya moyo wa zinthu zimafunika pafupifupi 2 hours. Nthawi yowonetsera kwambiri ndi maola 5, omwe amathandizidwa ndi mawonekedwe a thupi la wodwalayo.

Odwala Apadera ndi Mayendedwe

Mukamagwiritsa ntchito Humalog, kusamala kwina kumafunikira pokhudzana ndi magulu apadera a odwala. Matupi awo amatha kukhala osamala kwambiri ndi zovuta za insulin, motero muyenera kukhala anzeru.

Zina mwa izo ndi:

1. Amayi pa nthawi yoyembekezera. Mwachidziwitso, chithandizo cha matenda a shuga mwa odwala amaloledwa. Malinga ndi zotsatira za kafukufuku, mankhwalawa samavulaza kukula kwa mwana wosabadwayo ndipo samayambitsa mimbayo. Koma ziyenera kukumbukiridwa kuti munthawi imeneyi kuchuluka kwa shuga m'magazi kumatha kukhala kosiyana panthawi zosiyanasiyana. Izi ziyenera kuyang'aniridwa kuti mupewe zotsatira zoyipa.
2. Amayi oyamwitsa. Kulowetsedwa kwa insulin mkaka wa m'mawere sikowopsa kwa akhanda. Izi zimachokera kumapuloteni ndipo zimatengedwa m'matumbo a mwana. Chenjezo lokha ndiloti azimayi omwe amadyetsa mwachilengedwe ayenera kudya.

Kwa ana ndi okalamba posakhala ndi mavuto azaumoyo, chisamaliro chapadera sichofunikira. Humalog ndi yoyenera kulandira chithandizo chawo, ndipo adotolo ayenera kusankha mlingo wotsatira mawonekedwe a matendawa.

Kugwiritsa ntchito Humalog kumafunikira kukonzekereratu poyerekeza ndi matenda ena oyipa.

Izi zikuphatikiza:

1. Kuphwanya chiwindi. Ngati chiwalochi chikugwira ntchito moyipa kuposa momwe chikufunikira, ndiye kuti mankhwalawo atha kukhala ochulukirapo, zomwe zimabweretsa zovuta, komanso kukula kwa hypoglycemia. Chifukwa chake, pakakhala kulephera kwa chiwindi, mlingo wa Humalog uyenera kuchepetsedwa.
2. Mavuto a impso. Ngati lipezeka, kuchepa kwa kufunika kwa insulin kumawonedwanso. Pankhaniyi, muyenera kuwerengera mosamala ndi kuyang'anira njira yochiritsira. Kukhalapo kwa vuto lotere kumafuna kupenda kwakanthawi.

Humalog imatha kuyambitsa hypoglycemia, chifukwa chomwe kuthamanga kwazomwe zimachitika komanso kuthekera kwazomwe zimayang'ana zimasokonezedwa.

Chizungulire, kufooka, kusokonezeka - zinthu zonsezi zimatha kugwira ntchito kwa wodwala. Zochita zomwe zimafunikira kuthamanga komanso kusokonezedwa zimatha kukhala zosatheka kwa iye. Koma mankhwalawo pawokha samakhudza izi.

Zotsatira zoyipa ndi bongo

Kupezeka kwa zotsatira zoyipa kumatha kukhala koopsa. Wodwalayo ayenera kudziwitsa dokotala za kusintha komwe amapeza.

Mavuto omwe amakonda ndi awa:

• achina,
• khungu red
• kutupa
• kuyabwa
• malungo
• tachycardia
• kupsinjika
• thukuta kwambiri
• lipodystrophy.

Zina mwazomwe zili pamwambazi sizowopsa, chifukwa zimawonekera pang'ono ndikupita nthawi.

Ena amathanso kuyambitsa mavuto. Chifukwa chake, ngati zotsatira zoyipa zikuchitika, muyenera kufunsa dokotala wanu za kufunsa kwa chithandizo cha Humalog.

Afufuze zoopsa zomwe zingachitike, adziwe zomwe zimayambitsa (nthawi zina amanama pazolakwika za wodwalayo) ndikupereka chithandizo chofunikira chothandizira kuti matendawa asamayende bwino.

Mankhwala osokoneza bongo a mankhwalawa nthawi zambiri amakhala ndi vuto la hypoglycemic. Zitha kukhala zowopsa, nthawi zina mpaka kupha.

Amadziwika ndi zizindikiro monga:

• chizungulire
• kusokoneza chikumbumtima
• kukomoka mtima,
• mutu
• kufooka
• kutsika kwa magazi,
• kusokonezeka ndende,
• kugona
• kukokana
• kunjenjemera.

Kuwoneka kwa zizindikiro za hypoglycemia kumafuna kulumikizana ndi katswiri. Nthawi zina, vutoli limatha kuphatikizidwa ndi zinthu zomwe zili ndi mafuta ambiri, komanso zimachitika kuti popanda mankhwala sizingatheke kusintha momwe wodwalayo alili. Afunika kulowererapo kuchipatala mwachangu, chifukwa chake simuyenera kuyesetsa kuthana ndi vuto lanu.

Ndemanga za mankhwalawa ndizopikisana. Nthawi zina odwala sakonda chida ichi, ndipo amakana. Nthawi zambiri mavuto amabwera chifukwa chosagwiritsidwa ntchito molakwika pa Humalog, koma nthawi zina izi zimachitika chifukwa cha kusagwirizana pakapangidwe. Kenako dokotala yemwe akupezekapo ayenera kusankha mtundu wa mankhwalawo kuti apitirize chithandizo cha wodwalayo, koma kuti akhale otetezeka komanso bwino.

Monga cholowa chitha kugwiritsidwa ntchito:

1. Iletin. Mankhwalawa ndi kuyimitsidwa kwa mankhwala a isofan insulin. Imadziwika ndi ma contraindication ofanana ndi Humalog ndi zotsatira zoyipa. Mankhwalawa amagwiritsidwanso ntchito mosazindikira.
2. Osatinso. Chida chikuyimiriridwa ndi yankho. Maziko ake ndi insulin yaumunthu.
3. Farmasulin. Iyi ndi yankho la insulin yaumunthu.
4. Protafan. Gawo lalikulu la mankhwalawo ndi insulin Isofan. Amagwiritsidwanso ntchito pazochitika zofananira ndi Humalog, mosamala chimodzimodzi. Kukhazikika mu mawonekedwe a kuyimitsidwa.

Ngakhale kufanana kwazomwe amachita, mankhwalawa ndi osiyana ndi Humalog.

Chifukwa chake, mulingo wa iwo amawerengedwa, ndipo mukasinthira ku chida chatsopano, dokotala amayenera kuwongolera ndondomekoyi. Kusankhidwa kwa mankhwala oyeneranso ndi ake, chifukwa ndi iye yekha amene angawonetsetse kuopsa ndikuwonetsetsa kuti palibe zotsutsana.

Humalog ikhoza kugulidwa ku pharmacy iliyonse, ngati pali mankhwala kuchokera kwa dokotala. Kwa odwala ena, mtengo wake ungawoneke kukhala wokwera, pomwe ena amakhulupirira kuti mankhwalawo amawononga ndalama zotere chifukwa chogwira ntchito. Kupeza kwa makatoni asanu okhala ndi mphamvu ya kudzaza kwa 3 ml kudzafuna ma ruble 1700-2100.

Momwe kusiyana kwa QuickPen ™ Syringe Pens:

Kukonzekera cholembera kuti insulin ithe:

• Sambani m'manja ndi sopo.
• Chongani cholembera kuti muone ngati ali ndi mtundu wa insulin yomwe mukufuna. Izi ndizofunikira kwambiri ngati mugwiritsa ntchito mitundu yambiri ya insulin.
• Musagwiritse ntchito zolembera zomwe zatha ntchito monga zalembedwera.
• Nthawi zonse gwiritsani ntchito singano yatsopano ndi jekeseni aliyense kupewa matenda komanso kupewa kutchingira singano.

Gawo 1:

• Chotsani kapu ya cholembera.
  - Osachotsa cholembera cholembera.
• Pukutani disc ya mphira ndi swab choviikidwa mu mowa.

Gawo 2 (kungoti kukonzekera Humalog Remix 25 ndi Humalog Remix 50):

• Pindani pang'ono cholembera pakati pa manja anu kangapo.
• Ndipo
• Tembenuza syringe nthawi 10.

Kulimbitsa ndikofunikira pakulondola kwa mlingo. Insulin iyenera kuwoneka yunifolomu.

Gawo 3:

• Onani mawonekedwe a insulini.

Humalog® iyenera kukhala yowonekera komanso yopanda utoto. Osagwiritsa ntchito ngati ndi mitambo, ali ndi utoto, kapena tinthu tating'onoting'ono kapena mawonekedwe.

Humalog® Remix 25 iyenera kukhala yoyera komanso yamtambo mutasakaniza. Osagwiritsa ntchito ngati chowonekera, kapena ngati ma tinthu kapena mavu alipo.

Humalog® Mix 50 iyenera kukhala yoyera komanso yamtambo mutasakaniza. Osagwiritsa ntchito ngati chowonekera, kapena ngati ma tinthu kapena mavu alipo.

Gawo 4:

• Tengani singano yatsopano.
• Chotsani chomata papepala lakunja kwa singano.

Gawo 5:

• Ikani kapu ndi singano mwachindunji pa cholembera ndipo mutembenukire singano ndi kapu mpaka itagundika

Gawo 6:

• Chotsani thumba lakunja la singano. Osataya.
• Chotsani thumba lamkati la singano ndikuitaya.

Kuyang'ana cholembera kuti mugwiritse ntchito mankhwala osokoneza bongo

Kuyendera kotereku kuyenera kuchitika musanadulidwe aliyense.

• Kuyang'ana cholembera kuti mupeze mankhwala osokoneza bongo kumachitika kuti muchotse mpweya mu singano ndi cartridge, yomwe imatha kudziunjikira nthawi yayitali, ndikuonetsetsa kuti cholembera chikugwiradi ntchito.
• Ngati simupanga cheke chotere musanalowe jekeseni iliyonse, mutha kulowa insulin yotsika kwambiri kapena kwambiri.

Gawo 7:

• Kuti mupeze zolembera zama syringe pakumwa mankhwala, ikani ziwalo ziwiri mutembenuza batani la mlingo.

Gawo 8:

• Gwirani cholembera ndi singano m'mwamba. Dinani mopepuka chokolembera kuti thovu la mlengalenga lithe pamwamba.

Gawo 9:

• Pitilizani kugwira cholembera ndi singano mmwamba. Dinani batani la mlingo mpaka litayima ndipo "0" iwonekere pazenera la dokotala. Mukugwira batani la mlingo, pang'onopang'ono werengani mpaka 5.

Muyenera kuwona insulin kumapeto kwa singano.

- Ngati dontho la insulin silikupezeka kumapeto kwa singano, bwerezaninso zomwe mungachite kuti mupeze cholembera. Cheke chitha kuchitidwa osapitilira kanayi.
- Ngati insulini ilibe kuoneka, sinthani singano ndikubwereza cheke cholembera chida chamankhwala.

Kukhalapo kwa thovu laling'ono labwinobwino nkwachibadwa ndipo sikukhudza mlingo womwe umaperekedwa.

Sankhani

• Mutha kulowa kuchokera pa 1 mpaka 60 mayunitsi paliponse.
• Ngati mlingo wanu uposa 60 mayunitsi. Muyenera kuchita jakisoni wambiri.

- Ngati mukufuna thandizo la momwe mungagawire bwino mankhwalawa, funsani dokotala.
- Pa jakisoni aliyense, gwiritsani ntchito singano yatsopano ndikubwereza momwe mungayang'anire cholembera kuti mugwire mankhwala.

Gawo 10:

• Yatsani batani la mlingo kuti mupeze insulin yomwe mukufuna. Chizindikiro cha mlingo uyenera kukhala pamzere womwewo ndi kuchuluka kwa zigawo zomwe zikugwirizana ndi mlingo wanu.

- Nthawi imodzi, batani loyendetsa mlingo limasuntha 1 unit.
- Nthawi iliyonse mukatembenuza batani la mlingo, kumadina kumapangidwa.
- Simuyenera kusankha mlingo wowerengetsa makonda, chifukwa mlingo woyipa ungafanane motere.
- Mlingo umatha kusinthidwa ndikutembenuza batani mu njira yomwe mukufuna kufikira nthawi imeneyo. mpaka chithunzi chofanana ndi mlingo wanu chikuwonekera pawonetsero wa mlingo pazomwezo ndi chizindikiro cha mlingo.
- Ngakhale manambala akuwonetsedwa pamasamba.
- Manambala osavomerezeka, nambala 1 itatha, akuwonetsedwa ndi mizere yolimba.

• Nthawi zonse muziwunikira nambala yomwe ili pawindo lotsozera kuti muwonetsetse kuti mlingo womwe mwalowa ndi wolondola.
• Ngati pali insulin yotsalira mu cholembera kuposa momwe mungafunire, simungagwiritse ntchito cholembera kuti mulowetse muyezo womwe mukufuna.
• Ngati mukufuna kulowa mayunitsi ambiri kuposa omwe atsalira mu cholembera. Mutha:

- lowetsani voliyumu yotsalira mu cholembera chanu cha syringe, kenako gwiritsani ntchito cholembera chatsopano kuti mulowetse gawo lotsala, kapena
- tengani cholembera chatsopano ndi kulowa muyezo wathunthu.

• Pulogalamu yochepa ya insulin ikhoza kukhalamo.

Kubaya

• Lowetsani insulini ndendende monga momwe dokotala wasonyezera.
• Pa jakisoni aliyense, sinthani (sinthani) malo opaka jekeseni.
• Musayese kusintha mlingo pakati pa jakisoni.

Gawo 11:

Insulin imalowetsedwa pansi pa khungu (subcutaneously) kukhoma kwamkati, matako, m'chiuno, kapena mapewa.

• Konzani khungu lanu monga momwe dokotala wakupangira.

Gawo 12:

• Ikani singano pansi pa khungu.
• Kanikizani batani la mlingo mpaka njira yonse.

- Kugwira batani la mlingo. kuwerengetsa pang'onopang'ono mpaka 5, kenako ndikuchotsa singano pakhungu.

Osayesa kupereka insulin potembenuza batani la mlingo. Mukazungulira batani la mlingo, insulini SIYONSEZA.

Gawo 13:

• Chotsani singano pakhungu.
  Izi sizachilendo ngati dontho la insulin lingadutse kumphuno ya singano. ” Izi sizikhudzanso kuchuluka kwa mlingo wanu.
• Onani nambala yomwe ili pawindo la chizindikiro.
  - Ngati chiwonetsero chazenera cha mlingo ndi "0", ndiye. Mwalowa muyezo womwe mwamwa mokwanira.
  - Ngati simukuwona "0" pawindo lowonetsa, musayikenso mankhwalawo. Ikani singano pansi pa khungu kachiwiri ndikumaliza jakisoni.
  -Ngati mukuganiza kuti mlingo womwe mwayamwa sunalowe mokwanira, musabwereze jakisoni. Yang'anani shuga wanu wamagazi ndikuchita monga akuwongoleredwera ndi katswiri wanu wazachipatala.
  - Ngati mukufuna kupanga jakisoni 2 pa mlingo wonse, musaiwale jekeseni wachiwiri.

Ndi jakisoni aliyense, pisitoni imangoyenda pang'ono, ndipo mwina simungathe kuwona kusintha kwake.

Mukaona dontho la magazi mutachotsa singano pakhungu, ikanikizani mosamala ndi nsalu yoyera kapena daladala wambiri. Osazipukusa malowa.

Pambuyo jekeseni

Gawo 14:

• Valani bwino pakavalidwe kakunja ka singano.

Gawo 15:

• Tulutsani singano ndi kapu ndikutaya monga tafotokozera pansipa (onani gawo la "Dispping of Syringe Handles and needles").
• Osasunga cholembera ndi singano yomwe idasungidwa kuti muchepetse insulin, kutsekeka kwa singano, ndi mpweya kulowa cholembera.

Gawo 16:

• Ikani chipewa pa syringe cholembera, chikugwirizana ndi cholumikizira cap ndi chizindikiritso cha mlingo ndikuchikanikiza.

Kutaya zolembera ndi singano

• Ikani singano zogwiritsidwa ntchito mu chidebe cha sharps kapena chidebe cholimba cha pulasitiki chokhala ndi chivindikiro cholimba. Osataya singano m'malo osankhidwa zinyalala za m'nyumba.
• Chingwe chomwe chagwiritsidwa ntchito chitha kutayidwa ndi zinyalala za m'nyumba mutachotsa singano.
• Lumikizanani ndi adokotala za momwe mungatayire chida chanu cha ubweya.
• Malangizo ogwiritsa ntchito pobayira singano mu bukuli samachotsa malamulo, malangizo kapena mfundo zoyambitsidwa ndi bungwe lililonse.

Kusungidwa kwa cholembera

Zolembera zosagwiritsidwa ntchito

• Sungani manyunyu osagwiritsika ntchito mufiriji pa kutentha kwa 2 ° C mpaka 8 ° C.
• Osamasula insulin yanu. Ngati idapanga chisanu, musagwiritse ntchito.
• Ma cholembera osagwiritsidwa ntchito amatha kusungidwa mpaka tsiku lotha ntchito likawonetsedwa, ngati atasungidwa mufiriji.

Chingwe cha syringe chikugwiritsidwa ntchito

• Sungani cholembera chomwe mukugwiritsa ntchito panopo kutentha mpaka 30 ° C pamalo otetezedwa ndi kutentha ndi kuwala.
• Tsiku lotha ntchito lomwe lasonyezeredwa pamaphukusi litha, cholembera chogwiritsidwa ntchito chimayenera kutayidwa, ngakhale insulini ikadalimo.

Zovuta

• Ngati simungathe kuchotsa kapu ku cholembera, muzipotoza, kenako ndikukoka.
• Ngati piritsi loyimba lamankhwala lipanikizidwa kwambiri:
  - akanikizireni kuyimba pang'onopang'ono pang'onopang'ono. Kukanikiza pang'onopang'ono batani la kuyimba pang'onopang'ono kumapangitsa kuti jakisoniyo akhale wosavuta.
  "Singano ingatsekedwe." Ikani singano yatsopano ndikuyang'ana cholembera kuti mupeze mankhwala osokoneza bongo.
  -Nkutheka kuti fumbi kapena zinthu zina zalowa mu cholembera. Ponyani cholembera choterocho ndikutenga chatsopano.

Ngati muli ndi mafunso kapena mavuto pogwiritsa ntchito QuickPen Syringe pen, pezani Eli Lilly kapena wondithandizira.