Kodi madontho a methyl ethyl pyridinol ndi ati?

Jakisoni ndiwowoneka bwino, wopanda utoto kapena wachikasu pang'ono.

Othandizira: hydrochloric acid 0,1 M yankho - mpaka pH 2.5-3.5, madzi d / i - mpaka 1 ml.

1 ml - galasi ampoules (5) - matumba otupa (1) - mapaketi a makatoni.
1 ml - galasi ampoules (5) - matumba otupa (2) - mapaketi a makatoni.
1 ml - galasi ampoules (5) - mapaketi a makatoni.
1 ml - galasi ampoules (10) - mapaketi a makatoni.

Zotsatira za pharmacological

Angioprotector, amachepetsa kupezekanso kwa khoma la mtima, ndi cholepheretsa njira zosinthika, antihypoxant ndi antioxidant.

Imachepetsa kukhudzika kwa magazi ndi kuphatikiza kwa ma cell, kuonjezera zomwe zili mu cyclic nucleotides (cAMP ndi cGMP) m'mapulateleti ndi ubongo, imakhala ndi ntchito ya fibrinolytic, imachepetsa kutsimikiza kwa khoma la mtima komanso chiopsezo cha kukha mwazi, imalimbikitsa kuyambiranso. Amakulitsa ziwiya zama coronary, munthawi yovuta kwambiri ya infrction ya myocardial imachepetsa kukula kwa kuyang'ana kwa necrosis, imakweza mgwirizano wamtima ndi ntchito yamachitidwe ake. Ndi magazi ochulukirapo amakhala ndi hypotensive. Mu pachimake ischemic matenda a kufala kwa magazi kumachepetsa kukula kwa minyewa, kumawonjezera minyewa kukana hypoxia ndi ischemia.

Ili ndi katundu wa retinoprotective, imateteza retina ku zowonongeka za kuwala kozama kwambiri, imalimbikitsa kuyambiranso kwamitsempha yama cell, imakweza maso.

Zizindikiro zamankhwala

Monga gawo la zovuta mankhwala: zotsatira za cerebrovascular ngozi ya ischemic ndi hemorrhagic chikhalidwe, kuvulala kumutu, postoperative nthawi ya epi- ndi submatural hematomas, pachimake myocardial infarction, kupewa reperfusion syndrome, osakhazikika angina pectoris.

Subconjunctival and intraocular hemorrhage, angioretinopathy (kuphatikizapo matenda ashuga), chorioretinal dystrophy (kuphatikizapo atherosclerotic chiyambi), dystrophic keratitis, retinal vascular thrombosis, zovuta za myopia, kuteteza kwa cornea (mutavala magalasi oonera) kuwala kwakukulu (laser ndi kutentha kwa dzuwa, ndi laser-coagulation), zoopsa, kutupa ndi kuwotcha kwa ziphuphu, matenda amkati (kupewera kwa anthu opitilira 40), opaleshoni ya maso, mawonekedwe atachitidwa opareshoni kwa r laucoma wokhala ndi choroid.

Mlingo

Mu neurology ndi mtima - iv drip (20-25 madontho / mphindi), 20-30 ml ya yankho la 3% (600-900 mg) katatu pa tsiku kwa masiku 5-15 (kale mankhwalawa amathandizira mu 200) ml ya 0,9% NaCl yankho kapena 5% dextrose solution. Kutalika kwa chithandizo kumatengera matendawa. Pambuyo pake, amasintha kukonzekera makonzedwe - 3-5 ml ya yankho la 3% katatu patsiku kwa masiku 10-30.

Mu ophthalmology - subconjunctival kapena parabulbar, nthawi 1 patsiku kapena tsiku lililonse. Subconjunctival - 0,2-0,5 ml ya yankho la 1% (2-5 mg), parabulbar - 0.5-1 ml ya yankho la 1% (5-1 mg). Kutalika kwa mankhwalawa ndi masiku 10-30, ndikotheka kubwereza maphunzirowa katatu pachaka.

Ngati ndi kotheka, kubwezeretsani mu 0,5-1 ml ya 1% yankho 1 nthawi patsiku kwa masiku 10-15.

Kuteteza retina nthawi ya laser coagulation (kuphatikiza ndi kuchepetsa komanso kuwonongeka kwa zotupa) - parabulbar kapena retrobulbar 0,5-1 ml ya 1% yothetsera maola 24 ndi ola limodzi musanayambe kugundana, ndiye mulingo womwewo (0.5 ml iliyonse) 1% yankho) 1 nthawi patsiku kwa masiku 2-10.

Dzina la malonda

Patsamba logawa, madontho amaso amatchedwa Emoxipin, omwe ali ndi khemelo yayikulu yogwira methylethylpyridinol (methylethylpiridinol). Kuphatikizika kwake mu njira ndi 1%, i., 1 ml ya mankhwalawa muli 10 mg yofunikira.

Madontho amaso amapezeka mu pulasitiki, okhala ndi dontho, mabotolo odzazidwa ndimadzimadzi omveka bwino. Kuchuluka kwa iliyonse ndi 5 kapena 10 ml. Mabotolo amadzaza m'makatoni okhala ndi malangizo atsatanetsatane.

Analog ya madontho awa ndi Emoxy-Optic.

Methylethylpyridinol imapezekanso mu 1 ml ampoules. Njira yamtunduwu imagwiritsidwanso ntchito pochiza matenda amaso ndipo imatha kutumikiridwa mosadukiza (m'munsi m'maso) kapena mwachindunji pakatikati kamaso. Njira izi zothandizira pakhungu zimagwiritsidwa ntchito mu laser coagulation.

Malinga ndi malangizo, madontho amaso a Emoxipin amatha kusungidwa osaposa + 25 ° C kwa zaka ziwiri, ndipo atatha kutsegula - osapitilira masiku 30. Malo osungirako amayenera kutetezedwa kuchokera ku kuwala kwa dzuwa mwachindunji komanso kwa ana ochepa.

Malangizo ogwiritsira ntchito: Zizindikiro ndi ma contraindication

Maso akutsikira Emoksipin amagwiritsidwa ntchito pochiza ma pathologies amaso osiyanasiyana, kugwiritsa ntchito kwawo ndikothekanso kwa prophylactic:

• Matenda a shuga - kuchuluka kwa matenda ndi njira yayitali yodwalayo, yotchulidwa m'mafupa amitsempha yamagazi,
• Glaucoma - kuwonongeka kwamawonekedwe ndi kuwonjezeka kwakanthawi kapena kuwonjezereka kwa kukakamizidwa kwa intraocular,
• Myopia - myopia, pomwe kuwala kumalowera kumaso ndikuyang'ana nthawi imodzi popanda kufikira retina. Zotsatira zake, munthu salekanitsa zinthu pamtunda wautali,
• Hypermetropia - kuwona patsogolopa, kuyang'anizana ndi myopia. Wodwala amawona patali, ndipo pafupi ndi zinthu zimafalikira.
• Kuwotcha maso - kuwonongeka kwa chipolopolo chakunja chifukwa cha kuwonekera kwa mankhwala, ma t, ma radiation a ultraviolet, nthunzi.

Werengani zambiri za matenda a glaucoma apa.

Methylethylpyridinol ndi chida chothandiza pa matenda a yotupa mu kunja mucular nembanemba, pambuyo zoopsa zotupa, ndi mavuto a conjunctivitis.

Njira yokhayo yogwiritsira ntchito imaphatikizapo kuphatikiza diso lililonse 1 dontho 2-3 patsiku. Nthawi yayitali ya chithandizo ndi masiku 3-10. Komabe, monga adanenera dokotala, maphunzirowa atha kupitilizidwa mpaka mwezi umodzi. Kupititsa patsogolo kuthandizira kwamankhwala kumachitika potsatira malamulo ochepa osavuta:

• Sambani m'manja ndi sopo musanayambe ndi pambuyo pake,
• Musanagwiritse ntchito dontho, onetsetsani ngati pali zotchingira pamapeto zomwe zitha kuwononga diso,
• Mukamakulitsa, musakhudze dontho pamalo amaso,
• Pambuyo pa njirayi, tsitsani matope, ndikuchotsa chinyezi chilichonse chomwe chawoneka ndi nsalu yosalala,
• Chotsani magalasi olumikizana musanayambe kuphunzitsa mu mphindi 15. , ndipo musamavule kuposa mphindi 15. pambuyo pa njirayi.

Mutha kuwerengera zolemba pano.

Mankhwalawa, kuwonetsetsa kumatha kusokonekera, motero, anthu omwe akuchita zochitika zowonjezera ayenera kupuma.

Contraindication

Mndandanda wa zotsutsana za Emoxipin uli ndi zinthu zochepa, zokhala ndi zinthu zonse zokhudzana ndi zoletsedwa zomwe zimapezeka pafupifupi mu mankhwala aliwonse.

Kugwiritsa ntchito madontho amaso a methylethylpyridinol pamaso pazinthu zotsatirazi ndizoletsedwa:

• Hypersensitivity kwa yogwira mankhwala ndi zinthu zina,
• Zaka zodwala zopitilira 18
• Nthawi zobereka ndi kudyetsa mwana.

Kusamalidwa kwapadera kuyenera kuthandizidwa kwa odwala omwe ali ndi vuto losokonezeka poyambira, makamaka kumayambiriro kwa chithandizo. Ngati pali zovuta zilizonse zomwe sizisoweka pamachitidwe angapo, chithandizo chikuyenera kutha ndipo upangiri wina wachipatala uyenera kulandiridwa.

Pa nthawi yoyembekezera

Nthawi yachikondwerero (nthawi ya bere) -modzi wodziwika kwambiri m'moyo wa mayi aliyense. Mankhwala aliwonse osafunika pa nthawi yomwe ali ndi pakati, chifukwa nthawi zonse pamakhala chiopsezo chochepa chotengera mwana wosabadwa. Zinthu zina zimatha kulowa mu placenta.

Zachidziwikire, mukamagwiritsa ntchito madontho amaso, kuyamwa kwachilengedwe kumachitika pang'ono. Komabe, methyl ethyl pyridinol ndi chinthu cholimba chomwe chimakhudza njira zambiri za metabolic mthupi.

Kuletsa kugwiritsa ntchito mankhwalawa kumatengera kuchepa kwa deta yodalirika pazotsatira zomwe amagwiritsa ntchito, popeza, mwachilengedwe, palibe mayeso omwe amachitika pa amayi oyembekezera. Chifukwa chake, popeza mankhwalawa ndi mankhwala, kugwiritsa ntchito kwake kwamankhwala kuli ndi malingaliro a dokotala.

Kubwezeretsanso kwa macular - chithandizo cha mankhwala wowerengeka ndipo mankhwalawa akufotokozedwa m'nkhaniyi.

Ana aang'ono

Ponena za chithandizo cha ana, malangizowo amachepetsa zaka mpaka zaka 18 - izi zisanachitike, osavomerezeka kuchitira ana. Komabe, ena opanga amatanthauzira kuti kuletsa kumeneku kumapangidwanso chifukwa chosowa zotsatira zodalirika pakugwiritsa ntchito mankhwalawa.

Werengani zambiri za madontho amaso Dexamethasone paulalo.

Mwakuchita izi, madokotala a ana nthawi zambiri amalimbikitsa Emoxipine ngakhale kwa ana akhanda, popeza ana mankhwalawa opangira mankhwala am'njira zina za maso kulibe.

Mavuto omwe amatha chifukwa cha mankhwalawa

Ndemanga za odwala zimawonetsa kuti mankhwalawa nthawi zambiri amaloledwa. Nthawi zina, zovuta kumva mu mawonekedwe a thupi lawo siligwirizana ndikotheka: kuwotcha, kuyabwa, redness, lacrimation.

Pankhani yogwiritsa ntchito limodzi ndi mankhwala ena, tikulimbikitsidwa kugwiritsa ntchito Methylethylpyridinol pomaliza, pakatha mphindi 15. mutatha kugwiritsa ntchito mankhwala omaliza.

About madonthala a maso Tsiprolet alembedwa munkhaniyi.

Monga fanizo la mankhwalawa, Emoxy-optic, Emoxipin-AKOS, Emoxibel angagwiritsidwe ntchito.

Mankhwalawa ndi mankhwala othandiza kwambiri omwe angalimbikitse njira zambiri za metabolic m'matumbo amaso. Chifukwa chake, kugwiritsidwa ntchito kwake kwa njira zothandizira achihebri komanso prophylactic kungakhale koyenera pamaso pa ma pathologies angapo, komanso ndikuwopseza kukula kwawo.

Ngakhale kuti mankhwalawa ndi njira yowonetsera ponseponse, kugwiritsidwa ntchito kwake kuyenera kukhala koyenera ndikuchitika motsogozedwa ndi ophthalmologist.

Komanso werengani za mankhwala monga amprofloxacin akutsikira pazinthuzo.

Kutulutsa mawonekedwe ndi kapangidwe kake

Fomu ya Mlingo - jakisoni: wowoneka bwino, wopanda utoto kapena wamadzimadzi pang'ono chikasu, 1 ml iliyonse pamilili yopanda magalasi osalongosoka kapena kalasi yokhala ndi kalasi yokana kukakamira kwa hydrolysis ya HGA1, pamakatoni a 5 kapena 10 ampoules omalizira ndi vuto lalikulu (mukamanyamula ma ampoules ambiri ndi cholakwika sichinaphatikizidwe ndi mphete kapena malo osweka) kapena ma cell awiri ma cell am'mapulogalamu okwana 5 ndi malangizo ogwiritsira ntchito Methylethylpyridinol, kuwayika zipatala - pamakatoni okhala ndi 4, 5, 10, 50 kapena 100 ma encour cell 5 vayozi.

Muli 1 ml ya yankho:

• yogwira mankhwala: methylethylpyridinol (mu mawonekedwe a hydrochloride) - 10 mg,
• zothandizira: 0.1 M hydrochloric acid solution, madzi a jakisoni.

Mankhwala

Methylethylpyridinol ndi antioxidant, choletsa popanda njira zosinthira.

Imakhala ndi phindu pa kawonedwe ka magazi: imachepetsa kukhuthala kwa magazi, imachulukitsa nthawi ya kusokonekera kwake, komanso imalepheretsa kuphatikizika kwa magazi. Imakhazikika zimimba za maselo ofiira am'magazi ndi maselo amitsempha yamagazi, zimawonjezera kukana kwa maselo ofiira a magazi ku hemolysis ndi kuvulala kwamakina.

Imawonjezera zomwe zili mu cyclic nucleotides m'mapulatifomu (cyclic adenosine monophosphate ndi cyclic guanosine monophosphate), imachepetsa kutsekeka kwa khoma la mtima, imathandizira kuyambiranso kwa zotupa, komanso imakhala ndi ntchito ya fibrinolytic.

Amasintha kukhathamiritsa kwa m'maso a m'maso, kuphatikizapo ziwiya za m'maso. Ili ndi retinoprotective effect, imateteza retina ku zowonongeka za kuwala kwapamwamba kwambiri.

Zizindikiro zogwiritsidwa ntchito

Methylethylpyridinol imagwiritsidwa ntchito ngati gawo la zovuta kuchizira matenda / zinthu zotsatirazi:

• matenda am'mimba a cornea,
• intraocular ndi subconjunctival hemorrhages ochokera kumayendedwe osiyanasiyana,
• chapakati ndi zotumphukira za chorioretinal dystrophy,
• angioretinopathy (kuphatikizapo matenda ashuga),
• angiosulinotic macular degeneration (mawonekedwe owuma),
• thrombosis yam'kati mwa mtsempha wa retina ndi nthambi zake,
• zovuta za myopia,
• Digiri yachiwiri ndikuwotcha koopsa,
• Kutuluka kwa choroid mu postoperative nthawi pambuyo opaleshoni ya glaucoma,
• kuwonongeka kwa maso ndi kuwala kwamphamvu kwambiri (ma radiation a laser panthawi ya laser coagulation) - chithandizo ndi kupewa.

Methylethylpyridinol, ntchito malangizo: njira ndi mlingo

Methylethylpyridinol jakisoni njira imayendetsedwa parabulbarno (s / b) kapena subconjunctival (s / c). Mankhwala amagwiritsidwa ntchito ngati gawo la zovuta mankhwala.

Malangizo othandizira:

• matenda otupa a cornea: s / c 0,5 ml kamodzi patsiku masiku 10-30,
• intraocular ndi subconjunctival hemorrhages ochokera kosiyanasiyana: s / c kapena p / b 0.5 ml kamodzi patsiku kwa masiku 10-15,
• chapakati ndi zotumphukira chorioretinal dystrophy, youma mawonekedwe a angioscrotic macular alibe: 0,5 ml p / b kamodzi patsiku kwa masiku 10-15,
• thrombosis ya chapakati mtsempha wa retina ndi nthambi zake: n / a 0,5 ml kamodzi pa tsiku pakapita masiku 10-15,
• myopia yovuta: p / b 0.5 ml kamodzi patsiku kwa masiku 10-30, ngati ndi kotheka katatu pachaka, bwerezani maphunziro,
• kuvulala ndi kutentha kwa cornea wa 2 degree: p / b 0,5 ml 1 nthawi patsiku kwa masiku 10-15,
• ntchito ya choroid mu postoperative nthawi pambuyo opaleshoni mankhwala a glaucoma: s / c kapena p / b, 0,5-1 ml tsiku lililonse, njira ya mankhwalawa imakhala ndi jakisoni 10,
• chitetezo cha retinal panthawi ya laser coagulation (kuphatikiza ndi kuchepetsa komanso kuwonongeka kwa zotupa): p / b 0.5-1 ml maola 24 ndi ola limodzi musanayambe kugundana, ndiye kuti 0,5 ml 1 nthawi patsiku kwa masiku 2-10.

Zotsatira zoyipa

• zimachitika kwanuko: kuwotcha, kuwawa, kupweteka mtima, kuyabwa, kusokonekera kwa minofu ya paraorbital (sikutanthauza chithandizo chapadera, kutsimikiza mwaulere),
• thupi lawo siligwirizana: kuyabwa, khungu, edema, hyperemia,
• kuchokera ku dongosolo lamanjenje: kugona, kukwiya kwakanthawi,
• Kuchokera pamtima: zotupa za pakhungu, kuthamanga kwa magazi.

Kuyanjana kwa mankhwala

Methyl ethyl pyridinol siogwirizana ndi mankhwala ena, chifukwa chake ndizoletsedwa kusakaniza ndi syringe yomweyo ndi mankhwala ena.

Analogues a Methylethylpyridinol ndi awa: Vixipin, Cardioxypine, Methylethylpyridinol-Eskom, Emoxy-Optical, Emoksibel, Emoksipin, Emoksipin-AKOS, etc.

Ndemanga za Methylethylpyridinol

Ndemanga za methylethylpyridinol ochepa, koma zabwino. Mankhwala awonetsa kukhathamiritsa kwambiri, ndiokwera mtengo.Komabe, malinga ndi odwala, ndikosavuta kugwiritsa ntchito mankhwala omwe ali ndi mankhwala omwewo pogwiritsa ntchito madontho amaso.

Methylethylpyridinol amagwiritsidwa ntchito kawiri kawiri pama matenda osiyanasiyana a ophthalmological, komanso zovuta zamagazi ndi mtima.

Methylethylpyridinol: mitengo pamafakitale apakompyuta

Methylethylpyridinol 10 mg / ml jakisoni wa 1 ml 10 ma PC.

Methylethylpyridinol yankho d / mu. 10 mg / ml amp. 1ml №10 ELLARA

Maphunziro: Rostov State Medical University, apadera "General Medicine".

Zambiri zokhudzana ndi mankhwalawa ndizofanana, zimaperekedwa pazidziwitso ndipo sizilowa m'malo mwa malangizo ovomerezeka. Kudzipatsa nokha mankhwala kuopsa!

Poyamba zinkakhala kuti kumatheka kumapangitsa thupi kukhala ndi mpweya wabwino. Komabe, izi zidatsutsidwa. Asayansi atsimikizira kuti ukamadzuka, munthu amazizira ubongo ndikusintha magwiridwe ake.

Munthu wophunzira sakhala wokonzeka kutenga matenda aubongo. Ntchito zaluso zimathandizira kuti pakhale ziwalo zina zowonjezera kulipirira odwala.

Chiwindi ndi chiwalo cholemera kwambiri m'thupi lathu. Kulemera kwake pafupifupi 1.5 kg.

Ngati mungagwere kuchokera pabulu, mukulola khosi lanu kusiyana ndi kugwa kuchokera pa kavalo. Ingoyesani kutsutsa mawu awa.

James Harrison wazaka 74 yemwe amakhala ku Australia amakhala wopereka magazi pafupifupi nthawi 1,000. Ali ndi mtundu wamagazi osafunikira, ma antibodies omwe amathandizira akhanda omwe ali ndi vuto lalikulu la magazi kupulumuka. Chifukwa chake, waku Australia adapulumutsa ana pafupifupi mamiliyoni awiri.

Vibrator woyamba adapangidwa m'zaka za zana la 19. Adagwira ntchito pa injini yankhonya ndipo adapangira kuti azitsatira khungu la akazi.

Mwazi wa munthu "umayenda" m'matumbo omwe akukakamizidwa kwambiri, ndipo ngati umphumphu wake waphwanyidwa, amatha kuwombera mpaka 10 metres.

Asayansi ochokera ku Oxford University adachita kafukufuku wambiri, pomwe adazindikira kuti zamasamba zimatha kuvulaza ubongo wamunthu, chifukwa zimapangitsa kuchepa kwa kuchuluka kwake. Chifukwa chake, asayansi amalimbikitsa kuti asachotsere konse nsomba ndi nyama muzakudya zawo.

Mu 5% ya odwala, antidepressant clomipramine amayambitsa kuphipha.

Pa moyo, munthu wamba amapanga miyala yocheperako yoposa awiri.

Pogwira ntchito, ubongo wathu umagwiritsa ntchito mphamvu zambiri zofanana ndi babu la 10-watt. Chifukwa chake chithunzi cha babu wapamwamba pamutu panu panthawi yomwe chikuwoneka ngati chosangalatsa sichili kutali ndi chowonadi.

Madokotala a mano adapezeka posachedwa. Kalelo m'zaka za zana la 19, inali ntchito ya tsitsi wamba kuti akatulutse mano odwala.

Mankhwala odziwika bwino "Viagra" adapangidwa poyambirira pochizira matenda oopsa.

Amayi ambiri amatha kusangalala mwakuganizira za thupi lawo lokongola pakalilore kuposa kugonana. Chifukwa chake, akazi, yesetsani kuyanjana.

Mankhwala ambiri poyamba anali ogulitsidwa ngati mankhwala osokoneza bongo. Mwachitsanzo, a heroin adagulitsidwa ngati mankhwala a chifuwa. Ndipo cocaine adalimbikitsidwa ndi madokotala ngati opaleshoni komanso ngati njira yowonjezerera kupirira.

Polyoxidonium imakhudza mankhwala a immunomodulatory. Imagwira mbali zina za chitetezo chamthupi, potero zimathandizira kukulitsa kukhazikika kwa.

Pharmacokinetics

Kugawa voliyumu - malita 5.2. Kutha kwa theka-moyo ndi mphindi 18. Chilolezo chonse ndi 0,2 l / min. Wopangidwira m'chiwindi. Amachotsa impso.

Monga mbali ya zovuta mankhwala:

• Subconjunctival ndi intraocular hemorrhages a magawo osiyanasiyana,
• Angioretinopathy (kuphatikizapo matenda ashuga),
• Pakati ndi kotchedwa chorioretinal dystrophy,
• Thrombosis yamkati yam'mimba ndi nthambi zake,
• Mavuto a myopia
• Angiosulinotic macular degeneration (mawonekedwe owuma),
• Kudziwika kwa choroid mu postoperative nthawi pambuyo opaleshoni ya glaucoma,
• Matenda a Dystrophic a cornea,
• Kuvulala, kuwotcha ziphuphu,
• Chithandizo ndi kupewa kwa zilonda zam'maso ndi kuwala kozama (kuwala kwa dzuwa, kuwala kwa laser nthawi ya kuwala kwa laser).

Mlingo ndi makonzedwe

Mankhwala amagwiritsidwa ntchito ngati gawo la zovuta mankhwala.

Ndi ma subconjunctival komanso intraocular hemorrhages ochokera kosiyanasiyana - subconjunctival kapena parabulbar 0,5 ml kamodzi patsiku. Njira ya chithandizo ndi masiku 10-15.

Ndi angioretinopathy (kuphatikizapo matenda ashuga) - parabulbarno 0,5 ml 1 nthawi patsiku. Njira ya chithandizo ndi masiku 10.

Ndi chapakati komanso chotumphukira chorioretinal dystrophy, komanso antisranceotic macular degeneration (mawonekedwe owuma) - parabulbar 0,5 ml kamodzi patsiku. Njira ya chithandizo ndi masiku 10-15.

Ndi thrombosis ya chapakati retine mtsempha ndi nthambi zake - parabulbarno 0,5 ml kamodzi patsiku. Njira ya chithandizo ndi masiku 10-15.

Mu myopia yovuta - parabulbarno 0,5 ml kamodzi patsiku. Njira ya chithandizo ndi masiku 10-30, n`zotheka kubwereza maphunzirowa katatu pachaka.

Ndi choreid choroid odwala ndi glaucoma mu postoperative nthawi - parabulbar kapena subconjunctival 0,5-1.0 ml kamodzi pa masiku awiri. Njira ya mankhwala ndi jakisoni 10.

Zovulala ndi kuwotcha kwa ziphuphu za digiri yachiwiri - parabulbarno 0,5 ml kamodzi patsiku. Njira ya chithandizo ndi jakisoni 10-15.

Ndi dystrophic matenda a ziphuphu zakumaso - subconjunctival 0,5 ml kamodzi patsiku. Njira ya mankhwala ndi masiku 10-30.

Kuteteza retina nthawi ya laser coagulation (kuphatikiza ndi kuchepetsa komanso kuwonongeka kwa zotupa), 0,5-1.0 ml ya 1% yankho (5-10 mg) parabulbarly maola 24 ndi ola limodzi musanayambe kugundana, ndiye pamulingo womwewo ( 0,5 ml ya 1% yankho) 1 nthawi patsiku kwa masiku 2-10.

Bongo

Mu nkhani ya bongo, kuchuluka kuopsa kwa amadalira okhazikika zimachitikira mankhwala n`zotheka.

Zizindikiro: kuthamanga kwa magazi, kukwiya kapena kugona, kupweteka mutu, kupweteka mumtima, nseru, kusapeza bwino mu dera la epigastric. Matenda otulutsa magazi.

Chithandizo: kusiya mankhwala, chizindikiro, palibe mankhwala enaake.

Malangizo apadera

Chithandizo cha methylethylpyridinol ziyenera kuchitika motsogozedwa ndi kuthamanga kwa magazi ndi kuwundana kwa magazi.

Kukopa pa kuyendetsa magalimoto ndi kugwira ntchito ndi njira

Ndi kukula kwa kugona, ndikofunikira kukana kuyendetsa magalimoto ndi zinthu zina zoyenda, komanso kusamala mukamachita zinthu zomwe zingakhale zoopsa zomwe zimafunikira chidwi chachikulu komanso kuthamanga kwa zochitika zama psychomotor.

Kufotokozera za ntchito yogwira Methylethylpyridinol / Methylaethylpiridinolum.

Fomula C8H11NO, dzina la mankhwala: 3-hydroxy-6-methyl-2-ethylpyridine hydrochloride.
Gulu lamagulu: hematotropic mankhwala / antiplatelet othandizira, metabolism / antihypoxants ndi antioxidants, organotropic mankhwala / mtima othandizira / angioprotectors ndi ma microcirculation kukonza, mankhwala a organotropic / ophthalmic.
Machitidwe antihypoxic, antiaggregational, antioxidant, angioprotective, retinoprotective.

Mankhwala

Methylethylpyridinol ndi angioprotector, antihypoxant ndi antioxidant, ali ndi katundu wobwezeretsanso. Methylethylpyridinol amalepheretsa njira zosinthira mwaulere. Methylethylpyridinol imakhazikitsa cell membran. Methylethylpyridinol imakongoletsa microcirculation. Methyl ethyl pyridinol imachepetsa kuphatikiza kwa magazi ndi kuchuluka kwa magazi, imachepetsa kuchuluka kwa kuchuluka kwa magazi, imakulitsa nthawi yowonjezera magazi, imawonjezera zomwe zili mu cyclic nucleotides (cyclic guanidine monophosphate ndi cyclic adenosine monophosphate) mu minyewa ya ubongo ndi mapulateleti. Methylethylpyridinol ali ndi ntchito ya fibrinolytic, amalimbitsa khoma lamitsempha, amachepetsa kupezeka kwa khoma la mtima komanso chiopsezo cha kukha magazi, amalimbikitsa kuyambiranso kwa zotupa. Methylethylpyridinol imakhazikika pamimba ya maselo ofiira am'magazi ndi maselo amitsempha yamagazi, imawonjezera kukana kwa maselo ofiira a magazi ku hemolysis ndi kuvulala kwa makina. Methylethylpyridinol imawonjezera ntchito ya ma antioxidant michere, imalepheretsa makulidwe omasuka a lipids a biomembranes. Methylethylpyridinol ali ndi antitoxic zotsatira, amathandizira cytochrome P-450. M'mikhalidwe yowopsa, yomwe imayendetsedwa ndi hypoxia ndi kuchuluka kwa lipid peroxidation, methylethylpyridinol imakweza njira za bioenergy. Mu pachimake ischemic cerebrovascular ngozi, methylethylpyridinol amachepetsa kukula kwa minyewa kuwonekera, kumawonjezera minofu kukana ischemia ndi hypoxia. Pankhani ya ngozi ya cerebrovascular (hemorrhagic and ischemic), methylethylpyridinol imathandizira kukonza kukanika kwa kayendetsedwe ka zinthu, imathandizira ntchito za mnemonic, ndikuthandizira kubwezeretsanso kwa ntchito zogwirizira za ubongo. Methylethylpyridinol amachepetsa mapangidwe a triglycerides, ali ndi lipid yotsitsa. Methylethylpyridinol amachepetsa mitsempha ya mtima, amachepetsa kuwonongeka kwa myocardium, imathandizira ntchito ya conduction system ya mtima ndi contractility yamtima. Methylethylpyridinol amachepetsa kukula kwa kutsindika kwa necrosis, imathandizira njira zowongolera, imagwiranso kagayidwe kamtima ka minofu yamkati mwa myocardial infarction. Methylethylpyridinol ali ndi zotsatira zabwino pa chipatala cha kulowetsedwa kwa myocardial, kuchepetsa zomwe zimachitika mu mtima. Pankhani yolephera kuzungulira, methylethylpyridinol imathandizira kukhazikitsanso dongosolo la redox. Ndi kuthamanga kwa magazi, methyl ethyl pyridinol imakhala ndi hypotensive. Methylethylpyridinol amateteza retina ku zowonongeka za kuwala kozama kwambiri, kumapangitsa kusintha kwamaso, ndikuthandizira kuthana ndi kukha magazi kwa m'mitsempha.
Ikakhazikika mu conjunctival patsekeke, methylethylpyridinol imalowa mkati mwa tinthu timene timayang'ana, pomwe imayikidwapo ndikuwupanga. Kuphatikizika kwa methylethylpyridinol mu minyewa yamaso ndikwambiri kuposa m'magazi. Amamangidwa ndi mapuloteni am'madzi am'magazi pafupifupi 42%. Mothandizidwa ndi mtsempha wa methylethylpyridinol pa 10 mg / kg, theka la moyo (mphindi 18) linawonedwa, lomwe limawonetsa kuchepa kwa methylethylpyridinol m'magazi. Kuchotsa kosalekeza ndi mphindi 0,041. Methylethylpyridinol imalowa mwachangu mu minyewa ndi ziwalo, komwe imayikidwa ndikuwupanga. Kuchuluka kwawogawa kwa methylethylpyridinol ndi malita 5.2. Chilolezo chonse cha methylethylpyridinol ndi 214.8 ml / min. Ma metabolites asanu adapezeka, omwe amayimilidwa ndi dealkylated ndi conjugated methylethylpyridinol product changes. Methylethylpyridinol imapangidwa mu chiwindi. Mitundu yayikulu ya 2-ethyl-6-methyl-3-hydroxypyridine-phosphate yapezeka m'chiwindi. Methyl ethyl pyridinol metabolites amathandizidwa ndi impso. M'mikhalidwe ya pathological, mwachitsanzo, ndi coronary occlusion, pharmacokinetics of methylethylpyridinol kusintha: kuchuluka kwa chimbudzi kumachepa, chifukwa chomwe bioavailability ya methylethylpyridinol imachulukirapo, nthawi yomwe nyumba ya methylethylpyridinol ikukwera m'magazi, ikhoza kukhala chifukwa chakubwera kuchokera ku depo.

ischemic stroke, hemorrhagic stroke in the kuchira nthawi, kuperewera kwa vuto la kuchepa kwa thupi, kuchepa kwa vuto la kuchepa kwa magazi, zotsatira za kuchepa kwa magazi ndi kuchepa kwa magazi ndi vuto la kuchepa kwa magazi, kuvulala kwa ubongo, kupatsanso nthawi ya hematomas.
kupewa reperfusion syndrome, pachimake myocardial infarction, osakhazikika angina pectoris.
intraocular and subconjunctival hemorrhage, zotupa mu chipinda chakunja cha diso, zotupa m'mimba mu okalamba (kuphatikizapo kupewa), angioretinopathy (kuphatikizapo diabetesic angioretinopathy), dystrophic keratitis, angiosselotic maculodystrophy (youma forma, thrombosis, thrombosis mtsempha wapakati pa retina ndi nthambi zake, chorioretinal dystrophy (kuphatikiza ndi chorioretinal dystrophy yoyambira atherosranceotic), chitetezo cha ziphuphu x lenses) ndi retina kuti asayang'ane kuwala kwamphamvu kwambiri (ndi kuwala kwa laser, kuwotcha kwadzuwa ndi kuwala kwa laser), matenda a dystrophic a cornea, zovuta za myopia, matenda amtumbo (kuphatikizapo kupewa kwa matenda amtundu wazaka zopitilira 40) Zokhudza glaucoma yokhala ndi choroid chodzikongoletsera, njira zochitikira opaleshoni m'maso.

Njira yogwiritsira ntchito methylethylpyridinol ndi mlingo

Methylethylpyridinol imayendetsedwa kudzera m'mitsempha, intramuscularly, subconjunctival, parabulbar, retrobulbar, kukhazikitsa mu conjunctival patsekeke.
Mu conjunctival patsekeke, khazikitsani madontho 1 mpaka 2 (1% yankho) kawiri pa tsiku, kutalika kwa njira ya mankhwalawa kumatengera njira ya matendawa ndipo amatsimikiza ndi dokotala (nthawi zambiri mpaka masiku atatu mpaka 30), ngati mankhwalawa akwaniritsidwa ndipo pali zisonyezo, njira ya mankhwalawa zibweretsedwe mpaka miyezi isanu ndi umodzi kapena kubwereza kawiri mpaka katatu pachaka.
Subconjunctival kapena parabulbar imayendetsedwa kamodzi patsiku kapena tsiku lililonse. 0,2 - 0,5 ml ya yankho la 1% (2 - 5 mg) limayendetsedwa mosagwirizana, 0,5 - 1 ml ya yankho la 1% (5 - 10 mg) limayendetsedwa parabulbarly, nthawi ya chithandizo ndi masiku 10 - 30, n`zotheka kubwereza Inde, ngati pangafunike kutero, katatu kapena katatu pachaka. Ngati ndi kotheka, kuyambiranso 0,5 kwa 1 ml ya 1% yankho limaperekedwa kamodzi patsiku kwa masiku 10 mpaka 15. Pamene laser coagulation (kuphatikiza yowononga ndikuchepetsa zotupa), retrobulbar kapena parabulbar 0,5 mpaka 1 ml ya 1% yankho patsiku ndi ola limodzi musanayambe kutumikiridwa kuti muteteze retina, ndiye kuti 0,5 ml ya 1% yankho limaperekedwa kamodzi tsiku 2 kapena 10 masiku.
Angioretinopathy (kuphatikizapo matenda ashuga angioretinopathy): 0,5 ml parabulbarno (10 mg / ml methylethylpyridinol solution) kamodzi patsiku, maphunziro ake ndi masiku 10. Subconjunctival ndi intraocular hemorrhages ochokera kosiyanasiyana: parabulbarno kapena subconjunctival 0,5 ml (10 mg / ml methylethylpyridinol solution) kamodzi patsiku, njira ya chithandizo ndi masiku 10-15. Chapakati komanso zotumphukira za chorioretinal dystrophy, angiosulinotic macular degeneration (mawonekedwe owuma): 0,5 ml parabulbarno (methylethylpyridinol solution 10 mg / ml) kamodzi patsiku, njira ya chithandizo ndi masiku 10-15. Myopia yovuta: 0.5 ml parabulbarno (methylethylpyridinol solution 10 mg / ml) kamodzi patsiku, maphunziro ake ndi masiku 10-30, maphunzirowa akhoza kubwerezedwa kawiri kapena katatu pachaka. Thrombosis yamitsempha yayikulu ya retina ndi nthambi zake: 0,5 ml parabulbarno (methylethylpyridinol solution 10 mg / ml) kamodzi patsiku, maphunziro ake ndi masiku 10-15. Kudziwika kwa choroid odwala omwe ali ndi glaucoma mu nthawi yothandizira: subconjunctival kapena parabulbar 0,5 mpaka 1.0 ml (10 mg / ml methylethylpyridinol solution) kamodzi pakapita masiku awiri, maphunzirowo ndi jakisoni 10. Matenda a Dystrophic a cornea: subconjunctival 0.5 ml (10 mg / ml methylethylpyridinol solution) kamodzi patsiku, maphunziro ake ndi masiku 10-30. Kuvulala ndi kuwotcha kwa cornea ya digiri yachiwiri: 0,5 ml parabulbarno (methylethylpyridinol solution 10 mg / ml) kamodzi patsiku, maphunzirowo ndi jakisoni 10-15.
jekeseni wamitsempha (2040 akutsikira pamphindi), 20-30 ml ya yankho la 3% (600- 900 mg) 1 mpaka katatu pa tsiku kwa masiku 5 mpaka 5, kutengera zomwe zikuwonetsa ndi matenda ake 200 ml ya yankho la 5% ya dextrose kapena 0,9% yankho la sodium chloride), ndiye kuti amasinthana ndi jakisoni wa mu mnofu - 3 mpaka 5 ml ya yankho la 3% 2 mpaka 3 pa tsiku kwa masiku 10 mpaka 30.
kutumikiridwa m`nsinga minyewa (20-30 madontho pa mphindi) tsiku lililonse 5-10 mg / kg kwa masiku 10-12, ndiye kuti mu mnofu jakisoni wa 2-10 ml (yankho ndi kuchuluka kwa 30 mg / ml) (60-300 mg ) Katatu mpaka katatu patsiku kwa masiku 10 mpaka 30.
Methylethylpyridinol imagwiritsidwa ntchito ngati gawo la zovuta mankhwala.
Chithandizo cha methyl ethyl pyridinol ziyenera kuchitika mothandizidwa ndi kuphatikizika kwa magazi ndi kuthamanga kwa magazi ndi magazi.
Ngati kuli kofunikira kugwiritsa ntchito methylethylpyridinol mwanjira ya madontho amaso ndi mankhwala ena amtundu wamaso, methylethylpyridinol imakhazikitsidwa komaliza atamwa kwathunthu kwa mankhwala apitawo (osachepera mphindi 15).
Pa mankhwala omwe ali ndi methyl ethyl pyridinol, makamaka pamaso pa kugona, kutsitsa magazi, tikulimbikitsidwa kupewa kuchita nawo zinthu zoopsa zomwe zimafuna kuwonjezeredwa chidwi komanso kuthamanga kwa zochitika zama psychomotor (kuphatikizapo magalimoto oyendetsa, machitidwe).

Mimba komanso kuyamwa

Kugwiritsidwa ntchito kwa methylethylpyridinol kumachitika pakati pa mimba ndi mkaka wa m'mawere, popeza sipanakhalepo maphunziro okwanira komanso olamulidwa otetezeka a methylethylpyridinol pa nthawi ya pakati komanso mkaka wa m`mawere. Pa mankhwalawa ndi methyl ethyl pyridinol, kuyamwitsa kuyenera kuyimitsidwa.