Hypoglycemic wothandizira Combogliz Kutalika

Mankhwala othandizira odwala matenda ashuga ndi osiyanasiyana. Amasiyana mu mfundo yakusintha, mtundu wa kumasulidwa, kapangidwe kazinthu ndi zina.

Kuti ntchito ikhale yopindulitsa, muyenera kudziwa mawonekedwe a mankhwalawa. Chimodzi mwa izo ndi Combogliz Prolong. Iye, monga mankhwala ena, ali ndi machitidwe omwe amayenera kuzolowera.

Zambiri, kapangidwe ndi mawonekedwe ake amasulidwe

Mankhwalawa amagulitsidwa pansi pa dzina la Combogliz Pronge. Ili ndi vuto la hypoglycemic.

Amakhala ngati mapiritsi amtundu wa film. Mitundu yawo imatha kusiyanasiyana kutengera ndi zomwe zili ndi zinthu zomwe zimagwira.

Zigawo zazikulu za mapiritsiwa ndi zinthu ziwiri - Metformin ndi Saxagliptin. Zimakhala pansi pawo kuti zolinga zomwe zimakhazikitsidwa ndi mankhwalawa zimakwaniritsidwa.

Kuphatikiza pa iwo, mapangidwe a mankhwalawa amaphatikizapo:

• olimba ndi magnesium,
• hypopellose,
• carmellose
• titanium dioxide
• talcum ufa
• hydrochloric acid
• butanol
• propylene glycol
• utoto.

Pogulitsa mutha kupeza Combogliz ndi Mlingo wa 1000 + 2,5 mg (Metformin ndi Saksagliptin, motero), 500 + 5 mg ndi 1000 + 5 mg. Zadzaza matuza 7 ma PC. Bokosilo lili ndi matuza 4 kapena 8. Mtundu wa mapiritsiwo ukhoza kukhala wachikasu, bulauni, kapena pinki. Chigawo chilichonse chimalembedwa ndi zinthu zomwe zimagwira ntchito.

Pharmacological kanthu ndi pharmacokinetics

Mphamvu za mapiritsiwo zimatheka chifukwa cha kapangidwe kake, momwe mumakhala zinthu ziwiri zomwe zimagwira ntchito.

Chifukwa cha Saxagliptin, kusintha kwa mahomoni, maretretin, omwe amachititsa kuti insulini ipangidwe, imasungidwa.

Insulin imathandizira kuti glucose ayidwe mwachangu ndi maselo, omwe amatsimikizira kuchepa kwa kuchuluka kwake m'madzi a m'magazi. Komanso, maretretins amachepetsa kapangidwe ka shuga ndi chiwindi.

Mothandizidwa ndi gawo lachiwiri, Metformin, ntchito yopanga shuga m'chiwindi imachepa. Komanso, izi zimathandizira chidwi cha thupi ku insulin, yomwe imathandizira kuyamwa mwachangu ndikugawa shuga ndi minofu ndi ziwalo. Metformin sikukhudzana ndikupanga insulin.

Ikalowa mkatikati mwa thupi, saxagliptin imakhala yololera kwathunthu. Izi pafupifupi sizimagwirizana ndi mapuloteni amwazi. Kagayidwe kake kamachitika mothandizidwa ndi cytochrome isoenzymes, chifukwa chomwe metabolite yayikulu imapangidwa. Kugwiritsa ntchito kwazinthuzo kumachitika ndi matumbo ndi impso. Gawo la chinthucho limapukusidwa mosasinthika, ndalama zotsalazo zimachoka m'thupi mu mawonekedwe a metabolite.

Chochita chothandiza kwambiri cha Metformin chimadziwika pafupifupi maola 7 mutangoyambitsidwa kulowa m'thupi. Palibe chidziwitso chokwanira pakugawika kwa chinthuchi, koma zotsatira za kafukufuku wina zimawonetsa kukonda kwake pang'ono pokhudzana ndi mapuloteni amwazi. Excretion imachitika ndi impso, pomwe chigawochi chimapukusidwa mwa mawonekedwe ake oyambira.

Zizindikiro ndi contraindication

Gwiritsani ntchito mankhwala mosamala. Izi ndizowona makamaka za ndalama zomwe zimatsimikizira kusungidwa kwa zizindikiro zofunika. Popeza munthu amatha ngakhale kufa chifukwa chowonjezeka kapena kuchepa kwambiri kwa shuga m'magazi, mankhwala omwe ali ndi vuto la hypoglycemic ayenera kutengedwa pokhapokha akuwuzidwa ndi katswiri komanso kumwa mankhwala.

Chizindikiro chachikulu cha mankhwala a Combogliz Prolong ndi mtundu wa matenda a shuga 2. Koma asanavomereze mankhwalawa, adotolo ayenera kuonetsetsa kuti palibe zotsutsana. Ayeneranso kuwerengera mosamala, ndikuwonetsetsa zochitika zonse.

Mapiritsiwa ali ndi zotsutsana, chifukwa chomwe Combogliz sayenera kugwiritsidwa ntchito, ngakhale kukhalapo kwa odwala matenda a shuga osagwirizana ndi insulin.

Izi zikuphatikiza:

• chidwi ndi mtima wopanga,
• mtundu 1 shuga
• zosokoneza mu galactose kagayidwe,
• matenda a impso,
• matenda oopsa a mtima,
• lactic acidosis,
• kulephera kwa chiwindi
• metabolic acidosis
• Hypoxia ndi chiwopsezo cha kukula kwake,
• wazaka 18
• mimba
• yoyamwitsa.

Muzochitika zoterezi, tikulimbikitsidwa kuti mapiritsiwo asinthidwe ndi mankhwala ena. Kupanda kutero, thupi la wodwalayo limavulazidwa.

Malangizo ogwiritsira ntchito

Mankhwala aliwonse ayenera kugwiritsidwa ntchito molingana ndi malangizo. Koma malingaliro a adotolo nthawi zambiri amakhala ofunikira kwambiri, chifukwa malangizowo amakhala ndi chidziwitso chokhacho, ndipo katswiri amatha kupenda mawonekedwe amodzi payekha. Chifukwa chake, musagwiritse ntchito Comboglize popanda nthawi.

Mapiritsiwa amapangidwira pakamwa, omwe nthawi zambiri amachitika kamodzi patsiku. Izi zimachitika bwino madzulo. Phalepo silifunikira kuphwanyika ndi kutafuna - limameza madzi.

Mlingo umasankhidwa payekha. Nthawi zambiri amatsogozedwa ndi kuchuluka kwa Saksagliptin, gawo la tsiku lililonse lomwe sayenera kupitilira 5 mg. Mlingo woyenera wa Metformin koyambirira kwa mankhwala ndi 500 mg. Ngati ndi kotheka, ikhoza kuwonjezeka mpaka 2000 mg (ndiye kuti ndiyotheka kugwiritsa ntchito Combogliz 1000 + 2,5). Poterepa, mlingo wa mankhwalawa umagawidwa 2 Mlingo - m'mawa komanso madzulo.

Kuchulukitsa kwa mankhwalawa kuyenera kuchitidwa pang'onopang'ono, chifukwa mwinanso ndikotheka kuyambitsa chitukuko cha matenda a m'mimba.

Odwala Apadera ndi Mayendedwe

Mukamagwiritsa ntchito mapiritsiwa, ndikofunikira kuganizira kuti kusamala ndikofunikira kwa odwala ena.

Izi zikuphatikiza:

1. Anthu okalamba. Anthu odwala matenda ashuga opitilira zaka 60, omwe moyo wawo umaphatikizapo kugwira ntchito zolimbitsa thupi, ali pachiwopsezo chotenga lactic acidosis.
2. Amayi oyembekezera. Zotsatira za mankhwalawa pa nthawi yomwe mayi ali ndi pakati sizinafufuzidwe, chifukwa chake kugwiritsa ntchito kuyenera kupewa.
3. Amayi oyamwitsa. Palibe chidziwitso kaya ngati zinthu zodutsa zimalowa mkaka wa m'mawere. Popewa zoopsa zomwe zingachitike, chithandizo cha matenda ashuga ndi Combogliz sichimachitika panthawiyi.
4. Ana. Mankhwalawa sanayesedwe kuti akhale othandiza komanso chitetezo poyerekeza ndi anthu omwe ali ndi zaka zosakwana 18.

Izi magulu a odwala amafuna chithandizo ndi mankhwala ena.

Ndikofunikira kuzindikira ma comorbidities omwe alipo mu odwala matenda ashuga. Ena mwa iwo ndi chifukwa chokana kugwiritsa ntchito mankhwalawa pofunsidwa.

Izi zikuphatikiza:

1. Pancreatitis. Kuchita kwa zinthu zogwiritsidwa ntchito pancreas pamenepa kungakhale kosadalirika.
2. Kulephera kwa mtima. Ndi matenda awa, kugwiritsa ntchito Combogliz kungavulaze.
3. Matenda a chiwindi. Chifukwa cha kupezeka kwawo, mankhwalawa angayambitse kukula kwa lactic acidosis.
4. Matenda a impso. Vutoli limatha kuyambitsa kuchepa kwa zinthu zogwira ntchito mthupi, zomwe ndizowopsa ndi zovuta.

Matenda ena sakhala m'gulu la zotsutsana, koma ngati alipo, adotolo ayenera kuwunika zoopsa zake.

Zotsatira zoyipa ndi bongo

Mukamagwiritsa ntchito mankhwalawa ndi upangiri wa dotolo, mwayi wokhala ndi zotsatirapo zake zimakhala zochepa.

Nthawi zambiri, zinthu zoipa ngati izi zimatchulidwa kuti:

• mutu
• nseru
• kutupa kwa mphuno,
• Hypoglycemic mkhalidwe.

Ngati mukupeza zizindikiro zotere, muyenera kukambirana ndi dokotala. Nthawi zina amasintha mankhwalawo.

Mankhwala osokoneza bongo munthawi ya chithandizo ndi mapiritsi awa ndiwokayikitsa. Koma ndikuphwanya kwambiri malangizo, wodwalayo amatha kudwala matenda osiyanasiyana. Nthawi zovuta kwambiri, chithandizo chamankhwala chofunikira ndichofunikira.

Kuchita ndi mankhwala ena ndi analogi

Popeza pali zinthu ziwiri zogwira ntchito pakupanga mapiritsi a Combogliz, ngati kuli koyenera, kuphatikiza mankhwalawa ndi mankhwala ena, ndikofunikira kuganizira zachilendo zomwe zimachitika mogwirizana ndi gawo lililonse.

Mankhwala ena amatsogolera pakuwonjezeka kwa chinthu.

Pankhani ya saxagliptin, awa ndi:

Pa Metformin, izi zimachitika ndi:

• mankhwala okhala ndi zakumwa zoledzeretsa
• Furosemide
• Nifedipine.

Mu milandu yomwe mankhwalawa amafunikirabe kumwa, Mlingo wa Combogliz uyenera kuchuluka.

Kuchepetsa mphamvu ya mankhwala ndi saxagliptin angathe:

Mphamvu ya Metformin imafooka ndi:

• estrogens
• okodzetsa
• nicotinic acid
• amphanomachul.

Izi zikutanthauza kuti mukamamwa mankhwala aliwonse, muyenera kudziwitsa adotolo za iwo kuti athe kupanga mankhwala othandiza.

Kufunika kogwiritsa ntchito mankhwala analogue nthawi zambiri kumachitika chifukwa cha tsankho la mankhwalawa, zotsatira zoyipa kapena zotsika zake.

Nthawi zambiri, dokotala amatha kusankha zina mwa izi:

Kudzisankhira pawokha kwa analogues ya mankhwala sikovomerezeka.

Makanema pazithandizo zamitundu yachiwiri:

Maganizo a odwala

Popeza taphunzira kuwunika kambiri kwa odwala, titha kunena kuti mankhwalawa Combogliz Prolong amatha kulekerera komanso amachepetsa shuga m'magazi. Zotsatira zoyipa ndizosowa. Mukamamwa mankhwalawa, kuchepa thupi kumathandizidwanso.

Ndakhala ndikugwiritsa ntchito mankhwala osokoneza bongo ndi Metformin kwa nthawi yayitali. Nthawi zonse anali ndi zotulukapo zabwino. Chaka chatha, Combogliz Prolong idayamba kumwa. Shuga amakhala pamlingo woyenera, koma kulemera kwanga kwatsika kwambiri. Tsopano ndikupeza kuchokera kwa dokotala ngati ndizotheka kukana kumwa mapiritsi onse, ndikuwongolera shuga ndi zakudya.

Ndakhala ndi matenda ashuga kwa zaka 4. Munthawi imeneyi ndinayesa mankhwala ambiri, koma panali zovuta zina - mwina kulumikizana ndi mitengo ya shuga, ndiye mavuto. Chaka chatha, ndidayamba kutenga Combogliz Prolong. Palibe zoyipa zomwe zimachitika, mayesowo ndi abwino. Ndimakonda chilichonse.

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