Mapale 600 a Berlition: malangizo ogwiritsira ntchito

yogwira mankhwala - thioctic acid 600 mg

zokopa: mafuta olimba, sing'anga ma triglycerides.

chipolopolo: 70% sorbitol yankho, osakhala crystallizing (malinga ndi chinthu chamafuta), 85% glycerin (malinga ndi chinthu chamafuta), gelatin, titanium dioxide (E 171), carmine varnish (E 120).

Mankhwala

Mwa anthu, thioctic acid imalowa msanga pambuyo pakamwa. Chifukwa cha kutchulidwa kwa gawo loyambirira kudzera mu chiwindi, kukhudzika kwathunthu kwa bioavailability (poyerekeza ndi iv wakupangika) wa thioctic acid wotengedwa mkati ndi pafupifupi. 20% Chifukwa chakugawa mwachangu mu minofu, theka la moyo wa thioctic acid kuchokera ku plasma mwa anthu pafupifupi mphindi 25.

The bioavailability wa thioctic acid akagwidwa pakamwa mitundu yolimba imaposa 60% poyerekeza ndi mayankho amkamwa. Zolemba zazikulu za plasma za pafupifupi. 4 mcg / ml, itakwaniritsidwa pambuyo povomerezeka. 0,5 h pambuyo m`kamwa makonzedwe a 600 mg wa thioctic acid.

Poyeserera nyama (makoswe, agalu), pogwiritsa ntchito cholembera chazenera, zinali zotheka kuzindikira njira ya aimpso ya chimbudzi (80-90%), mwachitsanzo, ma metabolites. Mwa anthu, mafuta ochepa okha omwe amapezekanso mkodzo. Biotransformation imachitika makamaka ndi oxidative kufupikitsa kwam'mbali (beta oxidation) ndi / kapena ndi S-methylation ya motsutsana thiols.

Thioctic acid imakumana mu vitro ndi ma ion complexes (mwachitsanzo chisplatin). Thioctic acid wokhala ndi mamolekyulu a shuga amalowa m'maselo ochepa osungunuka.

Mankhwala

Thioctic acid ndi mankhwala okhala ngati vitamini koma amkati omwe amakhala ngati coenzyme mu oxidative decarboxylation wa alpha-keto acid. Hyperglycemia yoyambitsidwa ndi matenda a shuga amachititsa kuti shuga azikhala pamapuloteni amitsempha yamagazi ndikupanga zinthu zomaliza za glycosylation ("Advanced Glycosylation End Products"). Njirayi imayambitsa kuchepa kwa magazi a endoneural hypoxia / ischemia, omwe amaphatikizidwa ndikuwonjezeka kwa kupanga kwaulere kwa maukosi a okosijeni omwe amawononga mitsempha yotumphukira. Mu mitsempha yotumphera, kufooka kwa ma antioxidants, monga glutathione, kwapezekanso. Kafukufuku woyeserera akuwonetsa kuti thioctic acid imaphatikizidwa ndi njira zamtunduwu, kuchepetsa mapangidwe a glycosylation, kusintha kwa magazi a endoneural, ndikuwonjezera kuchuluka kwa thupi la glutathione antioxidant. Imagwiranso ntchito ngati antioxidant motsutsana ndi ma okosijeni amtundu wa okosijeni m'mitsempha yomwe imakhudzidwa ndi matenda a shuga. Zotsatira zomwe zimawonedwa pa kuyeseraku zikuwonetsa kuti mothandizidwa ndi thioctic acid, magwiridwe antchito a mitsempha yotukuka amatha kusintha. Izi zimagwira ntchito pazovuta zamatenda a matenda ashuga polyneuropathy, omwe amatha kuwonetsa ngati dysesthesia ndi paresthesia (mwachitsanzo, kuwotcha, kupweteka, dzanzi kapena kukwawa). Kafukufuku wachipatala akuwonetsa zotsatira zopindulitsa za thioctic acid mu chithandizo cha matenda ashuga polyneuropathy, omwe amatsatana ndi zizindikiro zodziwika bwino monga kuwotcha, paresthesia, dzanzi ndi kupweteka.

Pharmacodynamics ndi pharmacokinetics

Berlition imaphatikizanso ngati chophatikiza thioctic acid (alpha lipoic acid) mu mawonekedwe a ethylene diamine mchere, womwe ndi antioxidant wamkati womwe umamanga ma radicals aulere ndi coenzyme ya alpha-keto acid decarboxylation njira.

Chithandizo cha Berlition chimachepetsa plasma. shuga ndi kuwonjezera chiwindi glycogenkufooketsa insulin kukana, imalimbikitsa cholesterol, imayendetsa lipid ndi chakudya cha metabolism. Thioctic acidChifukwa cha chibadidwe chake cha antioxidant, chimateteza maselo a thupi la munthu ku zowonongeka zomwe zimapangitsa kuti ziwonongeke.

Odwala matenda ashuga thioctic acid amachepetsa kumasulidwa kwa zinthu zomaliza glycation wa mapuloteni m'mitsempha yama cell glutathione antioxidant. Chifukwa chakuchepetsa mphamvu ya shuga m'magazi a plasma, imakhudza njira yina ya kagayidwe kake.

Thioctic acid amachepetsa kudzikundikira kwa matenda polyol metabolites, potero amathandizira kuchepetsa kufinya kwamisempha yamanjenje. Limatulutsa kutsika kwa mitsempha kukakamira ndi mphamvu kagayidwe. Kuchita nawo mafuta kagayidwe, kumawonjezera biosynthesis phospholipidsZotsatira zake ndi momwe mawonekedwe owonongeka a ziwalo za cell amasinthidwanso. Amachotsa zoyipa mankhwala a metabolic za mowa (pyruvic acid, acetaldehyde), amachepetsa kutulutsidwa kwakukulu kwa mamolekyulu amtundu wa okosijeni, amachepetsa ischemia ndi wokhazikika hypoxiaZizindikiro zofooketsa polyneuropathymu mawonekedwe paresthesiakumverera koyaka, dzanzi ndi kupweteka mu miyendo.

Kutengera ndi zomwe tafotokozazi, thioctic acid imadziwika ndi hypoglycemic, neurotrophic ndi antioxidant ntchito, komanso kukonza lipid kagayidwe machitidwe. Gwiritsani ntchito pokonza chopangira chofunikira mu mawonekedwe mchere wa ethylene diamine imakupatsani mwayi wochepetsa zovuta zoyipa za thioctic acid.

Mukamamwa pakamwa, thioctic acid imatengedwa mwachangu komanso kumamwa kwathunthu kuchokera kumimba (chakudya chomwe chimayatsidwa limodzi zimachepetsa mayamwidwe mwanjira ina). TCmax mu plasma imasiyanasiyana pakati pa 25-60 Mphindi (iv. Ya 10-mphindi 10). Plasma Cmax ndi 25 38 mcg / ml. Bioavailability pafupifupi 30%, Vd pafupifupi 450 ml / kg, AUC pafupifupi 5 μg / h / ml.

Thioctic acid imayamba kugwira ntchito “yoyamba kudutsa” kudzera pachiwindi. Kupatula kwa zinthu za metabolic zomwe zimatheka mwa njira kuphatikizika ndi mbali yama oxidation. Kupereka mawonekedwe mu mawonekedwe a metabolites ndi 80-90% yochitidwa ndi impso. T1 / 2 imatenga pafupifupi mphindi 25. Chilolezo chonse cha plasma ndi 10-15 ml / min / kg.

Contraindication

Berlition imaphatikizidwa kwa odwala osakwana zaka 18, odwala omwe ali ndi hypersensitivity yogwira ntchito (thioctic acid) kapena zilizonse zothandizira pazomwe zimagwiritsidwa ntchito pochiza mtundu wa mankhwala, komanso kuyamwa ndi amayi apakati.

Mapale 300 a Berlition, chifukwa cha kupezeka kwa mawonekedwe awa lactosecontraindicated odwala ndi aliyense cholowa kusalolera shuga.

Mitundu yonse ya mankhwala

• kuphwanya / kusintha kwa kukoma,
• kuchepa kwa plasma zilishuga (chifukwa cha kusintha kwa mayamwidwe ake),
• Symbomatology hypoglycemiakuphatikiza kuwonongeka kwamawonekedwe, chizungulire, hyperhidrosis, mutu,
• matupi awo sagwirizanakuphatikizapo khungu zotupa/kuyabwazotupa za urticaria (urticaria), anaphylactic mantha (padera).

Kuphatikiza pa mitundu ya mankhwala

• diplopia,
• kuyaka m'dera la jakisoni,
• kukokana,
• thrombocytopathy,
• chinangwa
• kupuma movutikira ndi kuchuluka kwachuma kwachuma (zadziwika munthawi ya kayendetsedwe ka iv mofulumira ndipo zimadutsa zokha).

Berlition, malangizo ogwiritsira ntchito (Njira ndi Mlingo)

Malangizo oyendetsedwa ndi Berlition 300 ndi ofanana ndi malangizo ogwiritsira ntchito Berlition 600 pamitundu yonse ya mankhwalawa (jakisoni wa jekeseni, makapisozi, mapiritsi).

Mankhwala Berlition omwe amagwiritsidwa ntchito pokonzekera infusions amayambira kugwiritsidwa ntchito patsiku la 300-600 mg, omwe amaperekedwa tsiku lililonse mu kukapumira kwa mphindi zosachepera 30, kwa masabata 2-4. Atangoyambitsa kulowetsedwa, njira yothira mankhwala imakonzedwa ndikusakaniza zomwe zimapezeka mu 1 ampoule ya 300 mg (12 ml) kapena 600 mg (24 ml) ndi 250 ml Sodium Chloride Injection (0,9%).

Pokhudzana ndi photosensitivity ya okonzekera kulowetsedwa, iyenera kutetezedwa kuti isayerekezedwe ndi kuwala, mwachitsanzo, wokutidwa ndi zojambulazo ndi zotayidwa. Mwanjira imeneyi, yankho likhoza kusungidwa ndi malo pafupifupi 6.

Pambuyo pa milungu iwiri ndi itatu ya mankhwalawa pogwiritsa ntchito infusions, amasinthana ndi mankhwalawa pogwiritsa ntchito mitundu ya mankhwala. Mabotolo a Berlition kapena mapiritsi amatchulidwa muyezo wokonza tsiku lililonse wa 300-600 mg ndipo amatengedwa pamimba yopanda pafupifupi theka la ola musanadye, kumwa 100-200 ml ya madzi.

Kutalika kwa kulowetsedwa ndi njira yothetsera mkamwa, komanso kuthekera kochita kwawo mobwerezabwereza, kumatsimikiziridwa ndi dokotala aliyense payekha.

Bongo

Zizindikiro zoyipa za bongo wambiri thioctic acid kumawonekera nseru kugubuduzika masanzi ndi mutu.

Muzovuta kwambiri, zitha kuzindikirika kudziwa zolakwika kapena psychomotor mukubwadamukaophatikizidwa kukokana, hypoglycemia (asanafike chikomokere), mavuto azikuluzikulu za asidi lactic acidosislakuthwa minofu necrosis mafupa kulephera kwa ziwalo zingapo, hemolysis, DIC, kuletsa kwa mafupa ntchito.

Ngati mukukayikira kuwopsa kwa matenda a thioctic acid (mwachitsanzo, mutatenga mankhwala opitilira 80 mg pa 1 makilogalamu), tikulimbikitsidwa kuti wodwala azigonekedwa kuchipatala mwachangu ndipo nthawi yomweyo amayamba kutsatira njira zomwe zimagwiritsidwa ntchito pothana ndi poyizoni mwangozi (m'mimba thirakiti kuyeretsaphwando amatsenga etc.). M'tsogolomu, chithandizo chamankhwala chimasonyezedwa.

Chithandizo lactic acidosis, kukomoka kwakukulu ndi matenda ena oopsa omwe wodwalayo ayenera kufa nawo chisamaliro chachikulu. Zapadera mankhwala osadziwika. Pangopang, hemodialysis Njira zina zosefera sizothandiza.

Kutulutsa mawonekedwe ndi kapangidwe kake

Mlingo wa Berlition 600 ndi wothandiza pokonzekera njira yothetsera kulowetsedwa: mandimu omveka bwino, achikasu obiriwira 24 ml m'magalasi amdima (25 ml) ndi mzere wopumira (chizindikiro choyera) ndi mikwingwirima yobiriwira-chikaso chobiriwira, Ma PC 5. mu pallet ya pulasitiki, pamatoni 1

Mbale 1 ili ndi:

• yogwira mankhwala: thioctic acid - 0,6 g,
• zothandiza: ethylenediamine, madzi a jakisoni.

Pharmacokinetics

Mothandizidwa ndi mtsempha wa magazi, muyezo waukulu wa thioctic acid mu plasma umafikiridwa patatha mphindi 30. Mtengo wa C_max pafupifupi 20 μg / ml. Amapangidwa ndi makutidwe ndi okosijeni am'mbali, komanso conjugation. V_d (voliyumu yogawa) ndi 450 ml / kg. Thioctic acid ndi metabolites ake amuchotsa impso (njira yayikulu yakudziwitsira). Kuchotsa theka moyo ndi pafupifupi mphindi 25.

Berlition 600: malangizo ogwiritsira ntchito (Mlingo ndi njira)

Berlition 600 amaperekedwa kudzera mu mawonekedwe a kulowetsedwa.

Kumayambiriro kwa mankhwalawa, mankhwalawa amaperekedwa pa mlingo wa 600 mg patsiku (1 ampoule ya concentrate). Monga ulamuliro, njira ya mankhwala 2-2 milungu, kenako kukonza mankhwala ndi thioctic acid mu mawonekedwe a mapiritsi a 300-600 mg patsiku ikuchitika. Kutalika kwa mankhwala, komanso kufunikira kwa maphunziro obwereza, kumatsimikiziridwa ndi adokotala.

Kukonzekera njira yothetsera kulowetsedwa, zomwe zili m'mapapo amodzi zimaphatikizidwa mu 250 ml ya saline yachilengedwe. Njira yotsirizidwa imaperekedwa kudzera m'mitseko, pang'onopang'ono (osachepera mphindi 30). Thioctic acid ndi photosensitive, kotero mankhwalawa sayenera kuchepetsedwa pasadakhale. Njira yakonzekererayi iyenera kutetezedwa kuti isayerekezedwe ndi kuwala.

Zotsatira zoyipa

• kagayidwe: kawirikawiri - kuchepa kwa glucose wa plasma, nthawi zina mpaka hypoglycemia (yowonetsedwa ndi zizindikiro monga chizungulire, kupweteka mutu, kusawona bwino komanso kutuluka kwambiri),
• pakati ndi zotumphukira zamitsempha yamagetsi: kawirikawiri - kusintha kwa kakomedwe, kusokonezeka kwamaonedwe a mtima, kupweteka,
• hematopoietic dongosolo: kawirikawiri - thrombophlebitis, hemorrhagic zidzolo, magazi ochulukirapo chifukwa cha kuphwanya mapindikidwe am'magazi,
• thupi lawo siligwirizana: kawirikawiri - urticaria, kuyabwa, pakhungu pakhungu, patali milandu - anaphylactic mantha,
• zimachitika kwanuko: kawirikawiri kwambiri - kumverera koyaka pamalo a jekeseni wa kulowetsedwa,
• Zina: kupuma movutikira komanso kumva kutopetsa m'mutu (kuwoneka ndi mankhwala akumwa mwachangu ndikudziwonjezera)

Malangizo apadera

Odwala omwe ali ndi matenda a shuga omwe amatenga othandizira a hypoglycemic ayenera kuwunika kuchuluka kwa shuga m'magazi (makamaka kumayambiriro kwa mankhwala ndi Berlition 600). Izi ndizofunikira popewa kanthawi kochepa boma la hypoglycemic. Nthawi zina, kusintha kwa mankhwala a insulin kapena mankhwala a hypoglycemic angagwiritsidwe ntchito.

Ndi mtsempha wamkati, hypersensitivity zimachitika. Maonekedwe a kuyabwa kwa khungu, nseru, malaise kapena zizindikiro zina za hypersensitivity ndi chizindikiro cha kuthetseratu kwa thioctic acid.

Mowa umachepetsa mphamvu ya Berlition 600, kotero munthawi yamankhwala muyenera kusiya kumwa zakumwa zoledzeretsa.

Pulogalamu yokhayo ya 0,9% ya sodium koloridi ndi yomwe ingagwiritsidwe ntchito ngati chosungunulira kwa olimbitsa. Njira yothetserayo iyenera kusungidwa m'malo amdima, komanso yotetezedwa ku kuwala ndi zotayidwa ndi aluminiyamu. Alumali moyo wa yankho siopitilira maola 6.

Kukopa pa kuthekera koyendetsa magalimoto ndi njira zowerengeka

Palibe zambiri pazotsatira za Berlition 600 pa zomwe wodwala amatha kuchita mwakuya kapena kuyankha mwachangu vutoli, popeza palibe maphunziro apadera omwe adachitidwa. Pa chithandizo cha mankhwalawa, muyenera kusamala pochita ntchito iliyonse yokhudzana ndi chiwopsezo cha moyo ndi thanzi.

Kuyanjana kwa mankhwala osokoneza bongo

Berlition 600 imatha kupanga ma chelate ma iron, magnesium, calcium ndi zitsulo zina, kotero kugwiritsa ntchito nthawi yomweyo kuyenera kupewedwa.

Thioctic acid imakulitsa mphamvu ya hypoglycemic ya insulin ndi mankhwala amkamwa a hypoglycemic, komanso imachepetsa achire zotsatira za cisplatin.

Ethanol amachepetsa kwambiri zotsatira za Berlition 600.

Kukonzekera njira yothetsera kulowetsedwa, simungagwiritse ntchito mayankho a fructose, dextrose, glucose, Ringer, komanso mayankho omwe amagwirizana ndi mabulogu osagwirizana ndi ma SH-magulu.

Zofanizira za Berlition 600 ndi izi: Tiolepta, Thioctic acid-Vial, Thiogamma, Thioctacid 600 T, Lipoic acid, Alpha-lipoic acid, Thioctic acid, Lipothioxin, Berlition 300, Thioctacid BV, Espa-Lipon, Octolipen, Lipolion, Tolipion, Tolipion, Tolipion, Tolipion .

Ndemanga za Berlition 600

Mankhwalawa apeza ndemanga zabwino zambiri, chifukwa sizothandiza, komanso zolerera. Chifukwa cha kupyola mtima kwawo, Berlition 600 nthawi zambiri amagwiritsidwa ntchito pochiza zakumwa zoledzeretsa. Zimathandizanso kupewa komanso kuchiza matenda a shuga, kukhala othandiza kwambiri kuposa mitundu ina.

Malinga ndi ndemanga, Berlition 600 ilibe zolakwika, kupatula mtengo wamtengo wapatali.

Mlingo ndi makonzedwe

Mlingo wa tsiku ndi tsiku ndi kapisozi imodzi ya mankhwala Berlition® makapisozi mazana asanu ndi limodzi (600 mg wa thioctic acid), omwe amatengedwa kamodzi, pafupifupi mphindi 30 asanadye koyamba.

Ndi zovuta paresthesia, mutha kumayamba kulowetsedwa ndi thioctic acid.

Ana ndi achinyamata

Makapisozi a Berlition® 600 sayenera kutengedwa ndi ana komanso achinyamata

Makapisozi a Berlition® 600 ayenera kumwedwa pamimba yopanda kanthu, kumeza lonse ndikumwa madzi ambiri. Kudya nthawi imodzi kumapangitsa kuti mayamwa akhale ovuta. Chifukwa chake, kwa odwala omwe amadziwika ndi nthawi yayitali ya m'mimba, ndikofunikira kuti mankhwalawa atenge theka la ola musanadye chakudya cham'mawa.

Popeza ndi matenda osachiritsika odwala matenda ashuga a polyneuropathy, chithandizo chokwanira chingakhale chofunikira.

Maziko a chithandizo cha matenda ashuga polyneuropathy ndi omwe amawongolera kwambiri matenda a shuga.

Tulutsani mawonekedwe ndi ma CD

Makapisozi 15 amaikidwa mu chithuza cholumikizira cha PVC film (lined PVDH) ndi foil aluminium.

1 kapena 2 ma contour mapaketi pamodzi ndi malangizo ogwiritsira ntchito kuchipatala ndipo zilankhulo zaku Russia zimayikidwa mukatoni.

Sungani ku kutentha kosaposa 25 ° C.

Pewani patali ndi ana!

Osagwiritsa ntchito tsiku lanu litatha!

Kuchita

Chifukwa thioctic acid Khalidwe ndi mgwirizano wake ndi othandizira othandizira, kuphatikizapo maofiyamu azitsulo (mwachitsanzo ndi platinamu Cisplatin) Motere, kugwiritsidwa ntchito kophatikizana kwa Berlition ndi zitsulo kungapangitse kuchepa kwa ntchito yomaliza.

Monga munthawi yomweyo mankhwala a ethanol okhala kumabweretsa kuchepa kwa achire zotsatira za Berlition.

Thioctic acid imawonjezera ntchito ya hypoglycemic m`kamwa hypoglycemic mankhwala ndi insulinzomwe zingafune kusintha mtundu wawo.

Kuphatikizana kwa jakisoni sikugwirizana ndi mayankho a mankhwala omwe amagwiritsidwa ntchito ngati maziko akukonzekera kulowetsedwa, kuphatikizapo yankho la ringer ndi Dextrosekomanso mayankho omwe amayankhidwa ndi milatho yopanda tanthauzo kapena magulu a SH-magulu.

Thioctic acid imatha kupanga zovuta zosungunuka pang'ono ndi mamolekyulu a shuga.

Mankhwala Okhala Pamalo a Pharmacy

Wopanga / Mwini wa Setifiketi Yovomerezeka

BERLIN-HEMI AG (MENARINI GROUP)

Gliniker Veg 125

12489 Berlin, Germany

Packer

Catalent Germany Schorndorf GmbH, Germany

Adilesi ya bungweli kuvomereza madandaulo kuchokera kwa ogula pa mtundu wa zinthu (katundu) mdera la Republic of Kazakhstan:

Zoyimira JSC "Berlin-Chemie AG" ku Republic of Kazakhstan

Nambala yafoni: +7 727 2446183, 2446184, 2446185

Berlition kapena Heptral

Pokhudzana ndi hepatoprotective katundu wa Berlition, gulu la mankhwala omwe amabwezeretsa maselo a chiwindi, m'modzi mwa oimira otchuka omwe Heptral. Zachidziwikire, ndizovuta kutengera kufanana kwazokhudzana ndi zomwe othandizira awiriwa amathandizira, chifukwa akadali a magulu osiyanasiyana a mankhwala, amaphatikiza mitundu yosiyanasiyana yogwira ntchito ndipo amadziwika ndi njira zosiyanasiyana zochitira, komabe, pochiza matenda a chiwindi, nthawi zambiri amasinthidwa kapena kuthandizidwa.

Chifukwa chophunzitsidwa mosakwanira Berlition pa thupi la ana, kugwiritsa ntchito kwake kwa ana kumatsutsana.

Malangizo ogwiritsira ntchito

Berlition amatanthauza zochita za metabolic zomwe zimayendetsa kagayidwe ka mafuta ndi chakudya. Yogwira pophika mankhwala ndi thioctic acid. Mankhwalawa amapangidwa m'mapiritsi ndi mu mawonekedwe a gawo logona pakukonzekera njira yothetsera kulowetsedwa.

Berlition imalembedwa kwa odwala omwe ali ndi zotsatirazi:

• polyneuropathy, yopangidwa motsutsana ndi maziko a matenda osokoneza bongo komanso uchidakwa wovuta,
• steatohepatitis wamavuto osiyanasiyana,
• chiwindi steatosis
• mafuta hepatosis
• kuledzera kosatha.

Zotsatira zoyipa

Zotsatira zoyipa zotsatirazi zitha kuonedwa mu chithandizo cha Berlition:

Urticaria

Mitundu yonse yamiyeso:

• ziwengo, zomwe zimatha kudziwonetsa mu urticaria (mukamagwiritsa ntchito jakisoni, mitundu yonse ya matupi athu sagwirizana imatha kuchitika. anaphylaxis),
• kutsika kwa shuga m'magazi, monga glucose amatha kulowa bwino.

Mitundu ya jakisoni:

• kukokana
• masomphenya apawiri
• intracranial hyperplasia ndi kupuma movutikira (zimawonedwa ndi mankhwala mwachangu, zotsatira zoyipa izi zimadalira palokha),
• thrombophlebitis
• zotupa pakhungu ndi mucous nembanemba,
• kupendekera
• hemorrhagic zotupa,
• kulawa kosokoneza
• kuwotcha pamalo a jekeseni.

Piritsi 1 ili ndi 300 mg ya thioctic acid.

Monga zida zina zimaphatikizira:

• MCC
• mapasa
• shuga mkaka
• chofinya,
• E 572,
• croscarmellose sodium.

Chipolopolocho chimakhala ndi zinthu izi:

• titanium yoyera
• mafuta parafini
• hypopellose,
• sodium dodecyl sulfate,
• utoto E104 ndi E110.

Mu 1 ampoule of the concentrate pokonzekera njira yothetsera kulowetsedwa, 300 kapena 600 mg yogwira ntchito ikhoza kukhala.

Monga zinthu zothandiza, zomwe zimangokhala ndi madzi, ethylenediamine, ndi Berlition 300 zilinso ndi macrogol.

Pharmacology ndi pharmacokinetics

Thioctic acid ndi antioxidant. Monga coenzyme ya mitochondrial multienzyme imasinthasintha, imatenga gawo la oxidative carboxylation ya propanonic acid ndi alpha-keto acid.

Amachepetsa kuchuluka kwa shuga m'magazi ndikuwonjezera kuchuluka kwa glycogen m'chiwindi, amathandizira kuthana ndi insulin. Imayendetsa kagayidwe ka lipids ndi chakudya, imayendetsa ntchito ya chiwindi. Amachepetsa kuchuluka kwa shuga, lipids ndi cholesterol m'magazi, amakhala ndi hepatoprotective.

Mukamamwa pakamwa, imatengedwa bwino kuchokera m'mimba, pomwe nthawi yomweyo ndi chakudya, kuchuluka kwa adsorption kumachepa. Mothandizidwa ndi mtsempha wamitseko, pazipita mphindi 10, 60% itadulidwa pakamwa.

Kudutsa chiwindi, ntchito yogwira imapukusidwa, imapukusidwa kudzera mu impso.

Migwirizidwe yogula ndi kusungidwa

Mutha kugula mankhwala malinga ndi zomwe dokotala wakupatsani.

Ndikofunika kusungira moyikirapo pa kutentha kosaposa 25 digiri pamalo amdima pomwe ana sangathe kuwapeza.

Mankhwala sayenera kuzizira.

Alumali moyo wa kutsata ndi miyezi 36.

Mapiritsi amayenera kusungidwa m'malo osakwaniritsidwa ndi ana, kutentha osaposa 25 digiri. Moyo wa alumali ndi miyezi 24.

(Siyani ndemanga yanu mu ndemanga)

* - Mtengo wapakati pakati pa ogulitsa angapo panthawi yowunikira siwoperekedwa pagulu

Mtengo wa Berlition, kuti mugule

Ku Russia, mtengo wamba wa Berlition 600 mu ampoules No. 5 ndi ma ruble 900, ndipo Berlition 300 mumapulogalamu No. 5 ndi ma ruble 600. Mtengo wa Berlition 600 m'mabotolo No. 30 ndi pafupifupi ma ruble 1000. Mtengo wa Berlition 300 m'mapiritsi No. 30 ndi pafupifupi ruble 800.

Ku Ukraine (kuphatikiza Kiev, Kharkov, Odessa, ndi zina) Berlition pafupifupi ikhoza kugulidwa: ma ampoules 300 No. 5 - 280 hryvnia, ampoules 600 No. 5 - 540 hryvnia, makapisozi 300 No. 30 - 400 hryvnia, makapisozi 600 No. 30 - 580 hryvnia , mapiritsi 300 No. 30 - 380 hhucnias.