Indapamide yothamanga magazi

Indapamide ndi yachiwiri, yamakono kwambiri, yamtundu wamtundu wa thiazide-ngati diuretics. Chotsatira chachikulu cha mankhwalawa ndi kuchepa msanga, kosasunthika komanso kosakhalitsa kwa kuthamanga kwa magazi. Imayamba kugwira ntchito pambuyo pa theka la ora, pambuyo pa maola 2 zotsatira zake zimakhala zochuluka ndikukhalabe pamalo okwera kwa maola osachepera 24. Ubwino wambiri wa mankhwalawa ndi kusakhudzidwa kwa kagayidwe kazinthu, kuthekera kukonza impso ndi mtima. Monga ma diuretics onse, Indapamide ikhoza kuphatikizidwa ndi njira zotchuka komanso zotetezeka: sartans ndi ACE inhibitors.

Malangizo ogwiritsira ntchito

Momwe mungatenge indapamide

Indapamide iyenera kutengedwa kwa nthawi yayitali, mwina ngakhale kwa moyo wonse. Mankhwalawa amapangidwira kuti azigwiritsidwa ntchito kwa nthawi yayitali. Musayembekezere zotulukapo zachangu kuchokera pamenepo. Imayamba kutsika magazi osanachepera milungu iwiri kapena iwiri ya kudya tsiku lililonse. Imwani mapiritsi anu amtundu wa indapamide tsiku lililonse, 1 pc. Osamapuma phwando lawo popanda chilolezo cha adokotala. Mutha kudya diuretic (vasodilator) musanadye kapena mutamaliza kudya, monga mungafunire. Ndikofunika kuchita izi nthawi imodzi tsiku lililonse.

Indapamide iyenera kutengedwa mosalekeza, pokhapokha dokotala atakuwuzani kuti muchotse. Osawopa zotsatira zoyipa. Iyi ndi njira yotetezeka kwambiri yothamanga magazi komanso kulephera kwa mtima. Zizindikiro zosasangalatsa zomwe anthu amatenga chifukwa cha kuvulaza kwake nthawi zambiri zimakhala zotsatira za atherosulinosis, zomwe zimakhudza mitsempha yomwe imadyetsa mtima, ubongo ndi miyendo.Mukasiya kumwa indapamide, ndiye kuti matendawa sadzatha, ndipo chiwopsezo cha matenda a mtima ndi sitiroko chidzawonjezeka kwambiri.

Anthu ambiri amaganiza kuti kumwa indapamide ndi mankhwala ena atha kuyimitsidwa atatha kuthamanga magazi. Uku ndikulakwitsa kwakukulu komanso koopsa. Kuletsa chithandizo nthawi zambiri kumayambitsa kupanikizika, vuto la matenda oopsa, kugunda kwa mtima ndi sitiroko. Mankhwala othandizira odwala matenda oopsa ayenera kumwedwa mosalekeza, tsiku lililonse, mosasamala kanthu za kuthamanga kwa magazi. Ngati mukufuna kuchepetsa kumwa kapena kusiya kumwa mankhwala - kambiranani ndi dokotala. Kusintha kwa moyo wathanzi kumathandiza odwala ena oopsa kuti mankhwala athe kutha. Koma izi sizichitika nthawi zambiri.

Pamodzi ndi Indapamide, akufunafuna:

Mapiritsi Akukakamiza: Mafunso ndi Mayankho

• Momwe mungapangire matenda a kuthamanga kwa magazi, shuga ndi mafuta m'thupi
• Mapiritsi oponderezedwa ndi adotolo amawagwiritsa ntchito kuthandiza bwino, koma tsopano afooka. Chifukwa chiyani?
• Zoyenera kuchita ngati ngakhale mapiritsi amphamvu kwambiri samachepetsa kupanikizika
• Zoyenera kuchita ngati mankhwala oopsa kwambiri
• Kuthamanga kwa magazi, vuto la kuthamanga kwa magazi - mawonekedwe a mankhwalawa achichepere, apakati komanso okalamba

Indapamide yopanikiza

Indapamide yakhala njira yotchuka kwambiri yothamanga magazi chifukwa ili ndi phindu lalikulu. Mankhwalawa amachepetsa kuthamanga kwa magazi ndipo ndi otetezeka kwambiri. Ndizoyenera pafupifupi odwala onse, kuphatikizapo odwala matenda ashuga, komanso odwala matendawa ndi okalamba. Zilibe vuto lililonse mu metabolism - sizimakulitsa shuga (glucose) ndi uric acid m'magazi. Mapindu omwe atchulidwa pamwambapa apanga indapamide imodzi mwamankhwala oyambira kusankha matenda oopsa. Izi sizitanthauza kuti zitha kugwiritsidwa ntchito podzipaka nokha. Imwani mapiritsi aliwonse okhawo omwe akumwa ndi dokotala.

Indapamide siyabwino pamilandu yomwe mungafunike thandizo mwachangu ndi vuto la matenda oopsa. Imayamba kugwira ntchito mosakhalitsa pambuyo pa masabata 1-2 a kudya tsiku lililonse, ndipo imachepetsa kuthamanga kwa magazi. Pali mankhwala othamanga komanso oopsa a kuthamanga kwa magazi kuposa mankhwalawa. Koma mankhwala amphamvu amatha kuyambitsa mavuto ambiri nthawi zambiri. Monga lamulo, indapamide sichithandiza mokwanira ndi matenda oopsa ngati atchulidwa okha, popanda mankhwala ena. Cholinga cha mankhwalawa ndikuti magazi azitha kukhala osachepera 135-140 / 90 mm Hg. Art. Kuti mukwaniritse, nthawi zambiri muyenera kumwa indapamide pamodzi ndi mankhwala ena omwe si okodzetsa.

Kafukufuku wambiri omwe adachitika kuyambira m'ma 1980 adatsimikizira kuti kusayenda bwino kwa m'thupi kumachepetsa chiopsezo cha kugunda kwamtima, kugwidwa, ndi zovuta zina ku matenda oopsa. Ndikofunikira kuti odwala amwe piritsi limodzi lokha kuti azitsinkhidwa patsiku, osati mankhwala osiyanasiyana. Chifukwa chake, mankhwala omwe ali ndi ziwiri kapena zitatu zogwira ntchito piritsi limodzi atchuka. Mwachitsanzo, Noliprel ndi Co-Perineva ndi mankhwala okhala ndi indapamide + perindopril. Mankhwala Ko-Dalneva panthawi imodzimodzi amakhala ndi zosakaniza zitatu: yogwira amapodide, amlodipine ndi perindopril. Lankhulani ndi dokotala wanu za kugwiritsa ntchito mankhwala osakanikirana ngati muli ndi kuthamanga kwa magazi a 160/100 mmHg. Art. ndi mmwamba.

Indapamide nthawi zambiri imaperekedwa kwa odwala matenda a shuga mellitus ochokera kuthamanga kwa magazi komanso mankhwala ena. Mosiyana ndi mankhwala ena ambiri okodzetsa, mankhwalawa samachulukitsa kuchuluka kwa shuga m'magazi. Sizokayikitsa kuti muyenera kuwonjezera kuchuluka kwa mapiritsi a insulin komanso kutsitsa shuga mutayamba kumwa mankhwalawa. Komabe, tikulimbikitsidwa kulimbikitsa kuwongolera shuga, nthawi zambiri mumayeza shuga ndi glucometer.

Monga lamulo, odwala matenda ashuga amafunika kutenga indapamide osati okha, koma osakanikirana ndi mankhwala ena a kuthamanga kwa magazi.Yang'anani zoletsa za ACE zoletsa ndi angiotensin II receptor blockers. Mankhwala omwe ali m'magulu awa samangochepetsa kuthamanga kwa magazi, komanso amateteza impso ku zovuta za shuga. Amapereka kuchedwa pakukula kwa impso.

M'maphunziro ambiri azachipatala, odwala matenda a shuga adayikidwa indapamide + perindopril, yomwe ndi ACE inhibitor. Kuphatikiza kwamankhwala kumeneku sikuchepetsa kuthamanga kwa magazi, komanso kumachepetsa chiopsezo cha zovuta zamtima. Amachepetsa kuchuluka kwa mapuloteni mumkodzo. Izi zikutanthauza kuti impso sizivutika ndi matenda ashuga. Pakati pa odwala matenda ashuga, mapiritsi a Noliprel ndi otchuka, omwe amakhala ndi indapamide ndi perindopril pansi pa chigoba chimodzi. Kuthamanga kwa magazi kwa odwala omwe ali ndi matenda ashuga ndi 135/90 mm Hg. Art. Ngati Noliprel salola kuti ifike, ndiye kuti amlodipine amathanso kuwonjezeredwa ku regimen ya mankhwala.

Pansipa pali mayankho pamafunso omwe nthawi zambiri amakumana ndi odwala zokhudzana ndi mankhwala indapamide.

Kodi indapamide ndi mowa zimagwirizana?

Kumwa mowa kumawonjezera zovuta za indapamide, zomwe nthawi zambiri zimakhala zosowa. Mungamve kupweteka mutu, chizungulire, kapena ngakhale kukomoka ngati anzanuwo amatsika kwambiri. Komabe, palibe choletsa pagulu kumwa zakumwa za anthu omwe amamwa indapamide. Kumwa moyenera. M'masiku ochepa oyamba kumwa mapiritsi a kuthamanga kwa magazi, zotsatira zoyipa zomwe zatchulidwa pamwambapa ndizotheka kwambiri. Osamamwa mowa masiku ano, kuti muchepetse vutoli. Yembekezerani masiku pang'ono mpaka thupi lizolowere.

Kodi dzina loyambirira la mankhwala a indapamide dzina lake ndi ndani?

Mankhwala oyamba ndi mapiritsi a Arifon ndi Arifon Retard opangidwa ndi Servier. Mapiritsi ena onse okhala ndi indapamide ndi ofanana. Wantier ndi kampani yaku France. Koma izi sizitanthauza kuti mankhwala a Arifon ndi Arifon Retard amaperekedwa ku France. Fotokozerani dziko lomwe linachokera ndi barcode pa phukusi.

Kodi analogue otsika mtengo a mankhwalawa ndi chiyani?

Kukonzekera koyambirira Arifon (wokhazikika indapamide) ndi Arifon Retard (mapiritsi otulutsidwa otulutsidwa) ali ndi mitundu yambiri, yotsika mtengo kapena yotsika mtengo. Chonde dziwani kuti mapiritsi a Arifon ndi Arifon Retard siokwera mtengo kwambiri. Amapezeka ngakhale kwa nzika zapamwamba. Kusintha mankhwalawa ndi ma analogu kumakupulumutsirani ndalama zambiri. Pankhaniyi, kugwiritsa ntchito bwino mankhwalawa kumatha kuchepa komanso kuthekera kwa mavuto kumawonjezeka. Ku Russia, miyala yotsika mtengo ya indapamide imapangidwa ndi Akrikhin, Ozone, Tatkhimpharmpreparaty, Canonpharma, Alsi Pharma, Verteks, Nizhpharm ndi ena. Mayiko a CIS alinso ndi awo omwe amapanga mankhwala otchipa otchedwa Arifon.

Mndandanda wa mankhwala Indapamide:

Katswiri wamtima wodziwika mu zokambirana zopanda pake adavomereza kuti mwapadera salimbikitsa odwala ake kumwa mankhwala othandizira matenda oopsa a mtima komanso matenda amtima opangidwa ku Russia ndi mayiko a CIS. Onani apa kuti mumve zambiri. Ngati titenga ma analogu, ndiye kuti tcherani khutu ku indapamide, yomwe imapezeka ku Eastern Europe. Awa ndi mapiritsi a Indap ochokera ku kampani ya PRO.MED.CS (Czech Republic) ndi mankhwala omwe amapangidwa ndi Hemofarm (Serbia). Palinso indapamide-Teva, yomwe ikhoza kupezeka ku Israeli. Musanagule mankhwala aliwonse, tchulani dziko lomwe adachokera ndi barcode phukusi.

Kodi ndingatenge indapamide ndi Asparkam palimodzi?

Indapamide mwina samachotsa potaziyamu m'thupi. Chifukwa chake, sikofunikira kugwiritsa ntchito Asparkam kapena Panangin ndi mankhwalawa. Kambiranani izi ndi dokotala. Osatengera Asparkam nokha. Kuchuluka kwa potaziyamu m'magazi sikabwino, koma koopsa. Zingayambitse kuwonongeka kwaumoyo komanso ngakhale kufa chifukwa chomangidwa ndi mtima.Ngati mukukayikira kuti mukusowa potaziyamu, ndiye kuti tengani mayeso a magazi a mguluyu ndi ma electrolyte ena, ndipo musathamangire kumwa mankhwala kapena zakudya zamagetsi.

Kodi indapamide imakhudzanso potency yaimuna?

Kafukufuku wosaona kawiri, wowongoleredwa ndi placebo awonetsa kuti indapamide sidzafooketsa potency yaimuna. Kuwonongeka kwa potency kwa amuna omwe amamwa mankhwala oopsa nthawi zambiri kumachitika chifukwa cha atherosulinosis, yomwe imakhudza mitsempha yomwe imadzaza mbolo ndi magazi. Kusagonja nthawi zambiri kumachitika chifukwa cha zovuta za matenda ashuga, zomwe mwamunayo sakukayikira ngakhale kuti sakumuthandizira. Mukasiya kumwa mankhwalawo, ndiye kuti potency sangathe kusintha, ndipo vuto la mtima kapena stroke likuchitika zaka zingapo m'mbuyomu. Mankhwala ena aliwonse a diuretic operekedwa kwa matenda oopsa komanso kulephera kwa mtima kumakhudza amuna potency koposa indapamide.

Palibenso kupuma pang'ono, kupweteka mutu, kupsinjika ndi zizindikilo zina za HYPERTENSION! Owerenga athu akugwiritsa ntchito kale njirayi pofuna kuthana ndi mavuto.

Kodi indapamide imatsitsa kapena kuwonjezera magazi?

Indapamide amachepetsa kuthamanga kwa magazi. Kuchuluka kwake - zimatengera mawonekedwe a wodwala aliyense. Mulimonsemo, mankhwalawa samachulukitsa kukakamizidwa.

Kodi ndingatenge indapamide ndikapanikizika?

Funsani dokotala kuti akambirane kuchuluka kwa zomwe mungafunikire kuti muchepetse kuchuluka kapena kusiya indapamide. Osasintha mosasamala mlingo wa mankhwala ndi kuchuluka kwa mankhwalawa, pokhapokha ngati mukumva bwino kwambiri chifukwa cha kuthamanga kwa magazi.

Kodi ndingamwe mankhwalawa gout?

Mwinanso lero indapamide ndi mankhwala otetezeka a diuretic kwa odwala omwe ali ndi gout.

Kodi chimathandiza indapamide ndi chiyani?

Indapamide imapangidwira zochizira matenda oopsa, komanso kuchepetsa edema yoyambitsidwa ndi mtima kulephera kapena zifukwa zina.

Kodi ndingathe kumwa mankhwalawa tsiku lililonse?

Njira yotenga indapamide tsiku lililonse silinayesedwe pophunzira zamankhwala zilizonse. Mwinanso, njirayi siyingakutetezeni bwino ku vuto la mtima ndi sitiroko. M'masiku amenewo pamene simudzatenga indapamide, kudumpha kwa magazi kumachitika. Ndizowopsa m'mitsempha yamagazi. Matenda oopsa oopsa amathanso kuchitika. Osayesa kutenga indapamide tsiku lililonse. Ngati dokotala atakulembani dongosolo lotere, m'malo mwake ndi katswiri woyenereradi.

Indapamide 1.5 mg kapena 2 mg: zomwe zili bwino?

Kukonzekera kwachilendo kwa indapamide kumakhala ndi 2.5 mg ya chinthu ichi, ndi mapiritsi otulutsidwa otulutsidwa (MB, retard) ali ndi 1.5 mg. Mankhwala otulutsa pang'onopang'ono amachepetsa kuthamanga kwa magazi kwa nthawi yayitali kuposa mapiritsi a nthawi zonse ndipo amagwira ntchito bwino. Amakhulupirira kuti chifukwa cha izi, mlingo wa tsiku ndi tsiku wa indapamide umatha kuchepetsedwa kuchoka pa 2,5 kupita ku 1.5 mg popanda kusiya ntchito. Mapiritsi okhala ndi nthawi yayitali okhala ndi 1.5 mg ya indapamide ndi Arifon retard ndi analogues. Chonde dziwani kuti sioyenera kuthandizira edema. Amangopangidwira matenda oopsa. Kuchokera ku edema, indapamide iyenera kutengedwa monga momwe dokotala amafotokozera 2,5-5 mg wa patsiku. Mwina adotolo atipangireni mankhwala othandizira okodzetsa a edema, okodzetsa ziwalo.

Indap ndi indapamide: pali kusiyana kotani? Kapena ndi zomwezi?

Indap ndi dzina lamalonda la mankhwala omwe amapangidwa ndi kampani yaku Czech Pro.MED.CS. Indapamide ndizomwe zimagwira. Chifukwa chake, titha kunena kuti Indap ndi indapamide ndi ofanana. Kuphatikiza pa Indap ya mankhwala, mapiritsi ena ambiri okhala ndi diuretic (vasodilator) amagulitsidwa muma pharmacies. Odziwika kwambiri a iwo amatchedwa Arifon ndi Arifon Retard. Awa ndi mankhwala apachiyambi, ndipo Indap ndi zina zonse zakukonzekera kwa indapamide ndizofanizira zawo. Sizofunikira kuti Indap ipangidwe ku Czech Republic.Musanagule, ndikofunika kutchula dziko lomwe mankhwalawo adachokera ndi barcode phukusi.

Kodi pali kusiyana kotani pakati pa pafupipafupi indapamide ndi indapamide MV Stad?

Indapamide MV Stad imapangidwa ndi Nizhpharm (Russia). MB ikuyimira "kumasulidwa kosinthika" - mapiritsi otulutsidwa-otulutsa omwe ali ndi 1.5 mg yogwira mankhwala, osati 2.5 mg. Zikufotokozedwa mwatsatanetsatane momwe kuchuluka kwa indapamide 1.5 ndi 2.5 mg patsiku, komanso chifukwa chake sikoyenera kumwa mankhwala opangidwa ku Russia Federation ndi mayiko a CIS. M'magazini azachipatala chanyumba mutha kupeza zolemba zotsimikizira kuti indapamide MV Stada imathandizira ndi matenda oopsa kwambiri kuposa mankhwala oyambira Arifon Retard. Zolemba ngati izi zimasindikizidwa ndalama, choncho muyenera kukayikira za izo.

Zomwe zili bwino: indapamide kapena hydrochlorothiazide?

M'mayiko olankhula Chirasha, ndimakhulupirira kuti hydrochlorothiazide (hypothiazide) amachepetsa kuthamanga kwa magazi kuposa indapamide, ngakhale zimayambitsa zovuta zina. Mu Marichi 2015, nkhani ya Chingerezi idatuluka m'magazini yodziwika bwino ya Hypertension yotsimikizira kuti indapamide imathandizira kuthamanga kwa magazi kuposa magazi a hydrochlorothiazide.

Kafukufuku 14 adachitika pazaka zambiri, zomwe zimafanizira indapamide ndi hydrochlorothiazide. Zinapezeka kuti indapamide imakuthandizani kuti muzitha kuthana ndi magazi ndi 5 mm RT. Art. wotsika kuposa hydrochlorothiazide. Chifukwa chake, indapamide ndi njira yabwino yothetsera matenda oopsa kuposa hydrochlorothiazide malinga ndi mphamvu, komanso pafupipafupi komanso kuopsa kwa mavuto. Mwina hydrochlorothiazide bwino kuposa indapamide amathandizira ndi edema. Ngakhale onsewa mankhwalawa amawonedwa ngati ofooka. Sangolembedwera kwenikweni kwa edema yovuta.

Indapamide kapena furosemide: ndibwino bwanji?

Indapamide ndi furosemide ndi mankhwala osiyanasiyana. Furosemide nthawi zambiri imayambitsa zovuta, ndipo ndizovuta kwambiri. Koma mankhwalawa amathandiza ndi edema nthawi zambiri pamene indapamide ilibe mphamvu. Ndi matenda oopsa, osavutidwa ndi edema ndi vuto la mtima, dokotalayo atha kupereka indapamide. Dokotala wanzeru sakanatha kupereka furosemide yogwiritsira ntchito tsiku ndi tsiku chifukwa cha matenda oopsa chifukwa choopsa kwambiri cha zotsatira zoyipa. Koma ndi kulephera kwamtima kwakukulu kuchokera ku thandizo laling'ono la indapamide. Furosemide kapena chinthu china choopsa chotupa cha diuretic (Diuver) chimalembedwa kuti chithandizire kutupira komanso kufupika chifukwa cha kuchuluka kwa madzi m'mapapu. Izi sizikutanthauza kuti indapamide ndiyabwino kuposa furosemide, kapena mosemphanitsa, chifukwa mankhwalawa amagwiritsidwa ntchito mosiyanasiyana.

Indapamide kapena Noliprel: ndibwino bwanji?

Noliprel ndi piritsi lophatikiza lomwe lili ndi indapamide ndi chinthu china chowonjezera chomwe chimapanga perindopril. Amachepetsa kuthamanga kwa magazi kuposa momwe mungotengera indapamide popanda mankhwala ena. Kwa odwala omwe ali ndi kunenepa kwambiri komanso amtundu wa 2 shuga, Noliprel ndiyabwino kwambiri kuposa indapamide yokhazikika. Kwa odwala okalamba oonda, Noliprel atha kukhala wamphamvu kwambiri. Mwina ndi bwino kutenga mapiritsi a Arifon Retard kapena ma analogi awo. Lankhulani ndi dokotala wanu za mankhwala omwe ndi abwino kwa inu. Musamwe mankhwala ali pamwambawa nokha.

Kodi indapamide ndi lisinopril zitha kutengedwa nthawi yomweyo?

Inde mutha kutero. Kuphatikiza kwa mankhwalawa kwa matenda oopsa ndi chimodzi mwazabwino. Ngati indapamide ndi lisinopril palimodzi musalole kutsitsa magazi ku 135-140 / 90 mm RT. Art., Ndiye mutha kuwonjezera amlodipine kwa iwo. Kambiranani ndi adotolo anu, osangowonjezera chabe.

Indapamide kapena Lozap: ndibwino bwanji? Kodi mankhwalawa amagwirizana?

Izi sizikutanthauza kuti indapamide ndiyabwino kuposa Lozap, kapena mosemphanitsa. Mankhwalawa onse amachepetsa kuthamanga kwa magazi pafupifupi chimodzimodzi. Amakhala m'magulu osiyanasiyana a mankhwala oopsa.Indapamide ndi diuretic yomwe imagwiritsidwa ntchito ngati vasodilator. Lozap ndi angiotensin II receptor blocker. Mankhwalawa amatha kumwa nthawi yomweyo. Ndizotheka kuti atatengedwa, amachepetsa kuthamanga kwa magazi kwambiri kuposa aliyense payekhapayekha.

Kodi mankhwala a indapamide ndi enalapril ogwirizana?

Inde, amatha kutengedwa nthawi yomweyo. Enalapril ndiosavomerezeka chifukwa ziyenera kumwedwa kawiri pa tsiku. Lankhulani ndi dokotala wanu kuti muthane ndi imodzi mwatsopano monga mankhwala omwe ali okwanira kumwa piritsi limodzi patsiku.

Munthawi ya chithandizo chovuta kwambiri cha matenda oopsa, dokotala amayenera kupereka okodzetsa, popeza kuthamanga kwa magazi kumachepetsa mwachangu ndi kutulutsa kwamadzi m'thupi. Makampani opanga mankhwala apanga mankhwala ambiri okodzetsa. Nthawi zambiri, ngati pali edema, dokotala amalembera Indapamide kuti akapanikizike. Komabe, mankhwalawa ali ndi contraindication komanso mawonekedwe ogwiritsira ntchito, chifukwa chake amafunika kugwirizanitsa chithandizo ndi dokotala.

Mankhwala ndi a thiazide-ngati okodzetsa omwe amakhala nthawi yayitali, amatha kuchepetsa magazi. Indapamide imagwiritsidwa ntchito pochita matenda oopsa, pomwe kupanikizika kumayamba kupitirira 140/90 mm Hg. Art., Ndi kulephera kwa mtima kosatha, makamaka ngati wodwala watupa.

Mankhwala amamasulidwa monga mapiritsi ndi mapiritsi a 1.5 ndi 2.5 mg. Amapangidwa ku Russia, Yugoslavia, Canada, Macedonia, Israel, Ukraine, China ndi Germany. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa ndi Indapamide.

Indapamide ndi mankhwala osungira calcium, omwe ndi abwino kwa odwala matenda oopsa a mafupa. Itha kugwiritsidwa ntchito ndi anthu omwe ali ndi hemodialysis, odwala matenda ashuga, okhala ndi hyperlipidemia. Pazovuta, amafunikira kuti azilamulira kuchuluka kwa glucose, potaziyamu, zizindikiro zina zomwe adokotala akuuzidwa.

Makapiritsi kapena mapiritsi a kukakamiza kwa matenda oopsa amayamba kuchita mphindi 30 mutatha kumwa. Zotsatira za hypotonic zimatha maola 23-24.

Kuchepa kwa kuthamanga kwa magazi kumachitika chifukwa cha zotsatira za hypotensive, diuretic ndi vasodilating - kuthamanga kwa magazi kumayamba kutsika chifukwa cha mphamvu ya chinthu chomwe chikugwira, kuchotsa madzi owonjezera mthupi ndi kuchuluka kwa mitsempha yamagazi mthupi lonse.

Indapamide ilinso ndi katundu wamtima - amateteza ma cell a myocardial. Pambuyo pa chithandizo, matenda oopsa amatha bwino mkhalidwe wamanzere wamtima wamanzere. Mankhwalawa amachepetsa kukana mu zotumphukira ndi zotumphukira za arterioles. Popeza kuthamanga kwamkodzo kumayambitsa kuchuluka kwa mkodzo, komwe kumatsitsidwa madzimadzi ambiri, kuli koyenera kumwa mankhwalawo ngati pali edematous syndrome.

Pothamanga kwambiri (kuposa 140/100 mm Hg. Art.), Dokotala amasankha kuchuluka ndi nthawi yayitali ya mankhwalawa. Nthawi zambiri, Indapamide iyenera kumwedwa kamodzi patsiku: m'mawa, piritsi 1. Amaloledwa kumwa pamimba yopanda kanthu kapena atatha kudya - chakudya sichikhudza mphamvu ya mankhwalawa.

Malamulo ovomerezeka:

• gwiritsani ntchito nthawi yofotokozedwa bwino kuti musunge maola 24,
• mapiritsi kapena makapisozi amezedwa kwathunthu
• kuchapa ndi madzi osachepera 150 ml,
• Pokhapokha ngati dokotala akutsimikizirani, sinthani mulingo wake kapena musiyeni chithandizo.

Kukhalitsa kwa Indapamide kwa nthawi yayitali kumalumikizidwa ndi kufalikira kwa pang'onopang'ono kwa mankhwalawa. Ngati mupera mapiritsi kapena makapisozi musanagwiritse ntchito, kuchuluka kwake kwazomwe zimagwira kumalowera minofu, zomwe zimapangitsa kuchepa kwambiri kwa mavuto. Kutsika kwadzidzidzi kwa magazi kumasokoneza magwiridwe antchito onse amthupi, omwe amakhala ndi zotsatirapo zoopsa.

Mankhwala otsatirawa amaloledwa kumwa ndi Indapamide:

• Concor ndi ma B blockers ena,
• Lorista (imathandizira ma angiotensin receptors)
• Prestarium (chifukwa cha kulephera kwa mtima),
• Lisinopril (ACE inhibitor),
• mankhwala ena operekedwa ndi dokotala.

Mwachilengedwe, kuphatikiza kulikonse kwa mankhwalawa kumayenera kusankhidwa ndi adokotala okha, chifukwa ngati kuphatikiza kokhazikika kumachitika nthawi zambiri sikugwirizana. Izi zitha kuchititsa kulephera kwa mankhwalawa kapena poyizoni wa mankhwala osokoneza bongo, omwe mwanjira iliyonse amakhala pangozi ya moyo.

Nthawi zambiri munthu amakakamizidwa kumwa mankhwala angapo a magulu osiyanasiyana a mankhwala. Zinthu zawo zomwe zimagwira zimatha kuchepa kapena kuwonjezera mphamvu ya Indapamide. Ndikofunikira kudziwa mwatsatanetsatane momwe "zochitika" zotere zimawonekera.

Mphamvu ya antihypertensive ya mankhwalawa imawonjezeka ngati imagwiritsidwa ntchito limodzi ndi ma antidepressants, ma antipsychotic - izi zimatha kugwetsa kwambiri.

Akaphatikizidwa ndi erythromycin, munthu amakula tachycardia; mu cyclosporin zovuta, kuchuluka kwa creatinine kumawonjezeka. Kugwiritsa ntchito limodzi nthawi yomweyo limodzi ndi mankhwala osokoneza bongo, kuphatikizapo ayodini, kumatha kupangitsa kuti madzi asungunuke. Kutayika kwa potaziyamu kumalimbikitsidwa ndi mankhwala othandizira, ma saluretics ndi mtima glycosides.

Tiyenera kukumbukira kuti corticosteroids ndi NSAIDs (omwe si a antiidal anti-yotupa mankhwala) amachepetsa mphamvu ya Indapamide - izi zimachepetsa mphamvu ya mankhwalawa. Popewa kuyanjana kotere ndi mankhwala ena, dokotala amayenera kupereka mndandanda wazamankhwala onse azitsamba zomwe zimagwiritsidwa ntchito.

Odwala oopsa omwe ali ndi matenda amkodzo, endocrine, m'mimba ndi mtima dongosolo ayenera kuwonjezera kufunsa dokotala. Kwa ma pathologies ena, mankhwalawa ali ndi mawonekedwe ogwiritsira ntchito kapena amatsutsana kwathunthu.

Indapamide sayenera kugwiritsidwa ntchito mwa ana ochepera zaka 18, oyembekezera. Ngati mankhwalawa amadziwitsidwa kwa mayi panthawi ya mkaka wa m`mawere, ndiye kuti mankhwalawa mwana amasamutsidwa ku zakudya zosafunikira.

Kugwiritsa ntchito Indapamide kumatsutsana ngati zotsatirazi zikupezeka:

• tsankho
• kulephera kwa aimpso
• galactosemia, tsankho lactose,
• hepatic encephalopathy,
• kusokonezeka kwa magazi muubongo,
• hypokalemia
• gout
• anuria

Musanagule mankhwalawa, ndikofunikira kuti muphunzire malangizo omwe wapangidwira (omwe ali mu phukusi la mankhwalawo), chifukwa akuwonetsa zonse zokhudza kapangidwe kake, mawonekedwe ogwiritsira ntchito, zotsutsana ndi zina.

Kugwiritsa ntchito bwino mankhwalawa mu 97% ya milandu, mankhwalawa sasokoneza thupi. Mwa anthu omwe atsala 3%, Indapamide imayambitsa mavuto. Zotsatira zoyipa kwambiri ndikuphwanya muyeso wamadzi-electrolyte: kuchuluka kwa potaziyamu ndi / kapena sodium kumachepa. Izi zimadzetsa kusowa kwamadzi (kusowa kwamadzi) m'thupi. Osowa kwambiri, mankhwala amatha kuyambitsa arrhythmia, hemolytic anemia, sinusitis ndi pharyngitis.

Zotsatira zina za Indapamide:

• ziwengo (urticaria, anaphylaxis, edincke's edema, dermatosis, zidzolo),
• Matenda a Lyell
• Kuuma kwa mucosa wamlomo,
• Matenda a Stevens-Johnson
• kutsokomola
• kufooka
• chizungulire
• kusanza, kusanza,
• kupweteka kwa minofu
• migraine
• mantha
• kukanika kwa chiwindi
• kapamba
• kudzimbidwa
• orthostatic hypotension.

Nthawi zina indapamide imasintha kapangidwe ka magazi ndi mkodzo. Mu kusanthula kungawone kuchepa kwa potaziyamu, sodium, kuchuluka kwa calcium, shuga, creatinine ndi urea. Thrombocytopenia, leukopenia, kuchepa magazi, agranulocytosis kumachitika kawirikawiri.

M'malo mwa Indapamide, Indap imaloledwa. Mankhwalawa ali ndi mawonekedwe omwewo, koma amapangidwa ndi wopanga wina ndipo atha kukhala ndi muyeso wosiyana wa zomwe zimagwira. Pakakhala kusiyana, dokotala wopezekapo amayenera kusintha mankhwalawa.

Dokotala adzakuthandizaninso kuti mupeze ma fanizo omwe ali ndi chinthu chofanana kapena chochita.Pofunsidwa payekha, dokotala adzakuwuzani kuti ndi mankhwala ati omwe mungagwiritse ntchito: Indapamide kapena Hypothiazide, Arifon Retard, Veroshpiron, Hydrochlorothiazide, Diuver, Acriptamide, Ionic, Retapres. Mwina kutumikiridwa kwa ma diuretics ena omwe cholinga chake ndi kuchepetsa magazi.

Mankhwala Indapamide modekha amachepetsa kupanikizika tsiku lonse. Pogwiritsa ntchito nthawi zonse komanso molondola, kuthamanga kwa magazi kumachepa m'masiku 7 kuchokera poyambira kukhazikitsa. Koma chithandizo sichingasokonezeke pakadali pano, chifukwa mankhwalawa amafika pakapita miyezi iwiri ndi iwiri kapena itatu. Kuti mugwire bwino ntchito mankhwalawa, muyenera kutsatira malangizo azachipatala: kutsatira zakudya zamagazi, sinthani nthawi yopumula, mankhwala ena.

Indapamide ndi mankhwala okodzetsa a gulu la thiazide, omwe ali ndi hypotensive, vasodilator ndi diuretic (diuretic).

Mankhwalawa amagwiritsidwa ntchito pochiza matenda oopsa, a thiazide-ngati ndi thiazide diuretics amagwiritsidwa ntchito kwambiri mu antihypertensive mankhwala. Amagwiritsidwa ntchito ngati mankhwala oyambira ku monotherapy, ndipo monga gawo la chithandizo chophatikiza, kugwiritsa ntchito kwawo kumathandizira kusintha kwakukulu mu mtima.

Patsambali mupezapo zambiri zokhudzana ndi Indapamide: Malangizo onse omwe mungagwiritsire ntchito mankhwalawa, mitengo ya mankhwala, mankhwala, ndemanga zathunthu komanso zosakwanira, komanso ndemanga za anthu omwe agwiritsa ntchito Indapamide kale. Mukufuna kusiya malingaliro anu? Chonde lembani ndemanga.

Wodzikongoletsa. Mankhwala a antihypertensive.

Amamasulidwa pa mankhwala.

Kodi indapamide ndi zingati? Mtengo wapakati pama pharmacies uli pamlingo wa ma ruble 25.

Amapezeka mu mawonekedwe a makapisozi ndi mapiritsi omwe ali ndi chophatikizira chachikulu - indapamide, zomwe zili mu:

• 1 kapisozi - 2,5 mg
• 1 piritsi yokhala ndi utoto wa 2,5 mg
• Piritsi limodzi lautali wa zochitika pachithunzichi - 1.5 mg.

Zomwe zimapangidwira mapiritsi a Indapamide, okhala ndi mafilimu, amaphatikiza lactose monohydrate, povidone K30, crospovidone, magnesium stearate, sodium lauryl sulfate, talc. Chigoba cha mapiritsiwa chimakhala ndi hypromellose, macrogol 6000, talc, titanium dioxide (E171).

Zothandiza zigawo zam'mapiritsi zotulutsidwa zotulutsidwa: hypromellose, lactose monohydrate, silicon dioxide, colloidal anhydrous, magnesium stearate. Filamu sheya: hypromellose, macrogol, talc, titanium dioxide, utoto tropeolin.

Patsamba lamaukonde, kukonzekera kwa Indapamide kumalandiridwa:

• Makapisozi - okhala ndi ma polima a 10, 20, 30, 40, 50, 50, 100 kapena zodzaza matumba a zidutswa 10 kapena 30,
• Mapiritsi - matuza a 10 zidutswa.

Indapamide ndi m'gulu la mankhwala a thiazide diuretic ndipo ali ndi zotsatirapo zama cell:

1. Imachepetsa kukana mu arterioles,
2. Amachepetsa kuthamanga kwa magazi (hypotensive effect),
3. Imachepetsa kukhathamira kwamitsempha yonse,
4. Akutulutsa mitsempha yamagazi (ndi vasodilator)
5. Zimathandizira kuchepetsa kuchuluka kwa hypertrophy yam'manja yamitsempha yamtima,
6. Ili ndi moderate diuretic (diuretic).

Mphamvu ya antihypertensive ya Indapamide imayamba kutengedwa pakadontho (1.5 - 2,5 mg patsiku), zomwe sizimayambitsa kukokoloka. Chifukwa chake, mankhwalawa angagwiritsidwe ntchito kuchepetsa kuthamanga kwa magazi kwa nthawi yayitali. Mukamamwa mankhwala a Indapamide pamtokosi waukulu, zotsatira zake zimakhala zambiri, koma zotsatira zake zimatulutsidwa. Kumbukirani kuti kuchepa kwa kuthamanga kwa magazi kumatheka sabata yatha mutatha kumwa Indapamide, ndipo zotsatira zopitilira zimayamba pambuyo pa miyezi itatu yogwiritsidwa ntchito.

Indapamide siyimakhudzanso kagayidwe kazakudya ndi mafuta, chifukwa chake, amatha kugwiritsidwa ntchito ndi anthu omwe ali ndi matenda a shuga, cholesterol yayikulu, etc.Kuphatikiza apo, Indapamide bwino imachepetsa kukakamiza kwa anthu omwe ali ndi impso imodzi kapena hemodialysis.

Kodi chimathandiza ndi chiyani? Mankhwalawa adapangira zochizira matenda oopsa kwa odwala akuluakulu.

Ndi koletsedwa kumwa mankhwalawa ndikuwonetsa:

• hypokalemia
• mimba
• kuyamwa
• Kulephera kwaimpso (gawo la anuria),
• zaka mpaka 18 - (kuchita bwino ndi chitetezo sizinakhazikitsidwe),
• Hypersensitivity pamagawo a mankhwala,
• Hypersensitivity ena ofanana ndi sulfonamide
• hepatic encephalopathy kapena kwambiri chiwindi kulephera,
• lactose tsankho, kuchepa kwa lactase kapena glucose / galactose malabsorption.

Mochenjera, mankhwalawa amayenera kutumikiridwa ngati matenda aimpso ndi / kapena chiwindi, matenda a shuga m'magazi abwezeretsedwe, kuchepa kwamadzi ndi electrolyte bwino, hyperuricemia (makamaka ndi gout ndi nephrolithiasis). Zotsatira zake zomwe kutalika kwa nthawi ya QT ndikotheka (astemizole, erythromycin (iv), pentamidine, sultopride, terfenadine, vincamine, antiarrhythmic mankhwala a kalasi IA (quinidine, disopyramide) ndi kalasi III (amiodarone, bretilia tosylate)).

Kugwiritsa ntchito indapamide mwa amayi apakati sikulimbikitsidwa. Kugwiritsidwa ntchito kwake kukhoza kuyambitsa kukulitsa kwa ischemia ya placental, yomwe ingachedwetse kukula kwa mwana wosabadwayo.

Popeza indapamide imadutsa mkaka wa m'mawere, siyiyenera kufotokozedwa pa mkaka wa mkaka. Ngati kuli kofunikira kumwa mankhwalawa ndi odwala oyamwitsa, kuyamwitsa kuyenera kutha.

Malangizo ogwiritsira ntchito akuwonetsa kuti Indapamide imatengedwa pakamwa, mosasamala kanthu za kudya, makamaka m'mawa. Mapiritsi amayenera kumeza popanda kutafuna ndikumwa madzi ambiri.

• Ndi ochepa matenda oopsa, mlingo woyenera wa mankhwalawa ndi 2.5 mg 1 nthawi / tsiku.

Kuwonjezeka kwa mlingo wa mankhwalawa sikuti kumawonjezera mphamvu ya antihypertensive.

Mukamatenga Indapamide, kukula kwa zotsatirapo zake ndizotheka:

1. Kuchulukitsa kwa systemic lupus erythematosus,
2. Chifuwa, sinusitis, pharyngitis, kawirikawiri - rhinitis,
3. Urticaria, kuyabwa, zidzolo, hemorrhagic vasculitis,
4. Orthostatic hypotension, palpitations, arrhythmia, hypokalemia,
5. Matenda a kwamikodzo pafupipafupi, polyuria, nocturia,
6. Kusanza, kusanza, kudzimbidwa, kutsekula m'mimba, pakamwa owuma, kupweteka kwam'mimba, nthawi zina kwa chiwindi, kwa eppreatopathy,
7. Kugona, chizungulire, kupweteka mutu, mantha, asthenia, kukhumudwa, kusowa tulo, vertigo, kawirikawiri - malaise, kufooka, kusokonezeka, kuphipha kwa minofu, nkhawa, kusakhazikika,
8. Glucosuria, hypercreatininemia, kuchuluka kwa plasma urea nayitrogeni, hypercalcemia, hyponatremia, hypochloremia, hypokalemia, hyperglycemia, hyperuricemia,
9. Osowa kwambiri - hemolytic anemia, m'mapapo aplasia, agranulocytosis, leukopenia, thrombocytopenia.

Ngati bongo, kusanza, kufooka ndi mseru zingachitike, kuwonjezera, wodwalayo amakhala akusemphana ndi kugwira ntchito kwa m'mimba thirakiti komanso bwino kwamadzi.

Nthawi zina kupuma movutikira komanso kuchepa kwa magazi kumachitika. Pakakhala vuto losokoneza bongo, wodwalayo ayenera kutsuka m'mimba, kugwiritsa ntchito mankhwala othandizira, komanso kusintha moyenera magetsi amagetsi.

Munthawi ya chithandizo, chisamaliro chimayenera kuchitika poyendetsa magalimoto ndi kuchita zina zomwe zingakhale zoopsa zomwe zimafuna kuti anthu azisamalira komanso azithamanga kwambiri.

Tidalemba ndemanga za anthu okhudzana ndi Indapamide:

1. Valya. Dotolo adayambitsa Indapamide zaka zingapo zapitazo kuphatikiza ndi mankhwala ena atatu, atafika kwa dotolo ndi madandaulo a kuthamanga kwa magazi komanso kupweteka kwa mutu.Pang'onopang'ono adayamba kugwiritsa ntchito kokha, ndimamwa piritsi tsiku lililonse m'mawa, ndikasiya kumwa tsiku lotsatira nkhope yanga imatupa, matumba amawoneka pansi pamaso panga. Ndidamva kuti kugwiritsidwa ntchito kwa nthawi yayitali kumatha kubweretsa kuyambitsidwa kwa magnesium ndi calcium kwa thupi, nthawi zina ngati chiphuphu ndimamwa Asparkam.
2. Lana. Zaka 53, panali vuto la matenda oopsa zaka 4 zapitazo, matenda oopsa 2 tbsp., Adotolo adatulutsa indapamide 2,5 mg, enalapril 5 mg, ndi bisoprolol, chifukwa tachycardia nthawi zambiri, ndimamwa mapiritsiwa pafupipafupi m'mawa. Poyamba Bisoprolol adamwa, kenako adayamba kumva kupweteka mumtima mkati mwa iwo, tsopano ndi indapamide komanso enalapril. Kupsinjika m'mawa ndi 130 mpaka 95, madzulo kumachepa, chifukwa cha mapiritsi amatha kukhala 105 mpaka 90, ndipo pamene ali 110 mpaka 85, koma mtundu wina wa kutopa ndi kufooka kumamveka. Nthawi yotsiriza imakhala kupweteka mumtima.
3. Tamara Agogo akewo adapezeka kuti ali ndi matenda oopsa ndipo pofuna kuthana ndi vuto lakelo, dotolo wothandizira adamupatsa Indapamide. Ndinagula mankhwala muchipatala ndipo ndimapatsa wodwalayo m'mawa ndikupereka madzi akumwa. Zotsatira zake, izi zinapangitsa kuti agogo ake azikhala bwino masiku 10, kupanikizika sikunalumphe, koma kunayamba kuchepa (poganizira zaka zake). Pazonse, mankhwalawa adathandizira. Analimbikitsa.

Malinga ndi ndemanga, Indapamide ndi mankhwala othandiza kwambiri. Madotolo komanso odwala omwe ali ndi matenda oopsa amanenanso kuti mankhwalawa amaloledwa bwino. Zotsatira zoyipa ndizosowa kwambiri ndipo zimakhala zowuma. Odwala ambiri omwe amapezeka kuti ali ndi matenda oopsa amathanso mapiritsi m'moyo wawo wonse.

Mapiritsi a Indapamide ali ndi mapangidwe ofananikira pazomwe zimagwira. Awa ndi mankhwala ochizira kuthamanga kwa magazi:

• Acriptamide
• Acriptamide retard,
• Arindap, Arifon,
• Arifon retard (ofanana French),
• Vero-Indapamide,
• Indapamide MV-Stad (ofanana aku Russia),
• Indapamide Retard (ofanana ndi Russia),
• Mapangidwe a Indapamide,
• Zododometsa
• Indapsan
• Indipam
• Ionik
• Ionic retard
• Ipres kutalika
• Lorvas SR,
• Ravel SR,
• Kubwereza
• SR-Indamed.

Musanagwiritse ntchito fanizo, funsani dokotala.

Indapamide iyenera kusungidwa m'malo owuma otetezedwa ndi kuwala, kuchokera kwa mwana pamtunda wa 25 digiri.

Moyo wa alumali ndi miyezi 36, nthawi imeneyi itatha, mankhwalawo ndi oletsedwa.

Masiku ano, matenda ofala kwambiri ndi matenda oopsa kapena matenda oopsa. Mwanjira ina, uku ndi kuthamanga kwa magazi. Matendawa amakula chifukwa cha zinthu zakunja, mwachitsanzo, kupsinjika, kugwira ntchito kwambiri, kulimbitsa thupi, kusowa kupuma, kusintha kwakuthwa nyengo, kapena matenda a ziwalo zamkati. Tsoka ilo, matenda awa sangathe kuchiritsidwa kwathunthu, ndi matenda osachiritsika. Pazizindikiro zoyambitsa matenda oopsa, muyenera kufunsa dokotala. Katswiriyu amasankha chithandizo chamankhwala chimodzi chomwe chingathandize kuti magazi azithamanga komanso kuti achepetse zizindikiro zazikulu. Chithandizo chilichonse chimaphatikizapo diuretics, mankhwalawa ali ndi mitundu yosiyanasiyana yamankhwala, komabe, onse amachotsa bwino madzi owonjezera m'thupi. Mankhwala ndi okodzetsa. Nthawi zambiri dokotala amaphatikiza mankhwala Indapamide mu chithandizo chachikulu cha mankhwala, malangizo ogwiritsira ntchito komanso pazomwe angakakamize kumwa mankhwalawa m'nkhani ino.

Indapamide ndi diuretic yodziwika bwino yomwe imagwiritsidwa ntchito mwachangu pochotsa matenda oopsa, komanso kutupa komwe kumachitika chifukwa cholephera mtima. Mapiritsi amachotsa bwino magazi m'thupi ndipo amachepetsa mitsempha yamagazi, yomwe imathandizira kuchepa kwa magazi.

Mankhwalawa amasulidwa ngati mapiritsi, omwe amaphimbidwa pamwamba, oyera. Phukusi limodzi mumatha kukhala mapiritsi 10 kapena 30, omwe amalola munthu kudzisankhira kuchuluka koyenera.

Mankhwalawa amapangidwa ndi makampani ambiri azamankhwala, koma kapangidwe kake sikusintha. Chofunikira chachikulu ndi indapamide, piritsi limodzi lili ndi 2.5 mg. Kuphatikiza pa izi, mankhwalawa ali ndi zowonjezera zomwe zimakhudza thupi. Mankhwala ali ndi zinthu zothandiza monga izi:

• wowuma mbatata
• colidone CL,
• shuga kapena mkaka,
• magnesium wakuba,
• povidone 30,
• talcum ufa
• cellulose.

Zofunika! Kodi Indapamide imathandizira bwanji? Mankhwalawa amalembera kuthamanga kwa magazi. Zothandiza zake zimatha kuchotsa msanga madzi owonjezera m'thupi, komanso kukulitsa mitsempha yoyenera. Chifukwa cha izi, mankhwalawa amagwiranso bwino magazi.

Mankhwala amakhudzanso thupi. Zida zake zimachotsa msanga madzi ndi mchere wambiri m'thupi. Amathandizira kupangika kwamkodzo kwamkodzo, komwe kumathandizira kuchotsa madzimadzi kuchokera ku minofu ndi ma serous cavities.

Indapamide ndi diuretic yapamwamba kwambiri yomwe ili diuretics ya thiazip. Kuphatikiza apo, mankhwalawa amachepetsa mitsempha yamagazi ndikuwongoletsa makoma a mtima. Pamodzi, izi zimatha kuchepa magazi komanso kusintha mkhalidwe wa munthu.

Ngati mlingo watsiku ndi tsiku ndi 1.5-2.5 mg, ndiye kuti ndizokwanira kupewa kuchepa kwa ziwiya, zomwe zikutanthauza kuti kupanikizika kuzikhala mwa malire. Kuphatikiza apo, chizolowezi ichi chimathandiza kukonza makoma amitsempha yamagazi komanso chimateteza minofu yamtima kuti isasinthe pamagazi. Zikatero, ngati kuchuluka kwa mankhwalawa kumawonjezeka mpaka 5 mg patsiku, ndiye kuti kuchuluka kwake kudzakhala kokwanira kuti muchepetse kutupa. Komabe, mlingo wowonjezereka sukukhudzanso kuchuluka kwa kukakamizidwa.

Ndi kugwiritsa ntchito pafupipafupi, zotsatira zowoneka zimatheka pambuyo masiku 7-14 atamwa mankhwalawa. Mankhwalawa amatha kwambiri pambuyo pa miyezi iwiri ya chithandizo cha 2-3. Zotsatira zabwino zimakhala kwa milungu 8. Ngati mapiritsi amatengedwa kamodzi, ndiye kuti zotsatira zake zimafunikira m'maola 12-24.

Ndikwabwino kumwa mankhwalawa pamimba yopanda kanthu kapena mukatha kudya, popeza kugwiritsa ntchito piritsi ndi chakudya kumachepetsa mphamvu yake mthupi, koma sikukukhudzika kwake. Zigawo zogwira ntchito za Indapamide zimalowa mwachangu m'mimba, motero zimagawidwa mthupi lonse.

Chiwindi chimayeretsa bwino mafuta omwe amapanga mapiritsi. Komabe, amawapanga ndi impso ndikuwachotsa pamodzi ndi mkodzo (70-80%) patatha pafupifupi maola 16. Kuchulukitsa kudzera mu ziwalo zogaya chakudya ndi pafupifupi 20-30%. Chofunikira chachikulu mu mawonekedwe ake oyera chimapakidwa pafupifupi 5%, ziwalo zina zonse zimagwira mthupi.

Indapamide ndi mankhwala othandiza omwe amagwiritsidwa ntchito kwambiri ngati mankhwala kuti abwezeretse magazi. Monga lamulo, madokotala amalimbikitsa izi ngati matenda amthupi:

• matenda oopsa a 1 ndi 2 degrees,
• kutupa chifukwa cha kulephera mtima.

Indapamide tikulimbikitsidwa kuti mutenge piritsi (2,5 mg) kamodzi patsiku. Iyenera kumezedwa yonse popanda kutafuna, ndikutsukidwa ndi madzi ambiri. Komabe, ngati chithandizo sichikwaniritsa zotsatira zofunikira pambuyo pa miyezi 1-2, ndiye kuti mlingo woyenera ndi woletsedwa kuti uwonjezeke, chifukwa chiopsezo chokhala ndi zotsatirapo zake chikuwonjezeka. Panthawi imeneyi, dokotala angalimbikitse kusintha mankhwalawa kapena kuwonjezeranso ndi mankhwala ena.

Mankhwalawa ayenera kuyikidwa ndi adokotala okha, chifukwa pali zingapo zotsutsana zomwe ndizofunikira kuziganizira mukamatenga Indapamide. Monga lamulo, mapiritsi saloledwa kupereka zoterezi:

• matenda a impso (aimpso kulephera),
• matenda a chiwindi
• kusowa kwa potaziyamu m'thupi la munthu,
• kusalolera kwa chimodzi mwa zigawo za mankhwala,
• Mimba ndi kuyamwa
• ana ndi achinyamata osakwana zaka 18,
• ndi matenda ashuga
• madzi osakwanira m'thupi,
• ngati pali gout
• Co-kuperekera mankhwala kuwonjezera nthawi ya QT.

Zofunika! Indapamide iyenera kutumizidwa ndi adokotala okha. Katswiri amadziwa momwe wodwalayo alili ndi zina zomwe mankhwalawo ali nazo.

Mapiritsi a mankhwala nthawi zonse amaloledwa bwino, koma anthu onse ndi osiyana, kotero zizindikiro zosasangalatsa nthawi zina zimatha kuonedwa. Mankhwala, ziwalo za Indapamide zimadziunjikira m'thupi, zomwe zimatha kupweteka kosiyanasiyana. Pakati pazizindikiro zazikulu, madokotala amati:

• ziwalo zam'mimba (nseru, kusanza, kutsegula m'mimba, kudzimbidwa, kuwuma pamlomo wamkamwa),
• dongosolo lamanjenje (kupweteka mutu, kugona kapena kugona, kugona kwambiri, mantha),
• minofu (kukokana kwambiri kwa minofu),
• ziwalo zopumira (pharyngitis, sinusitis, chifuwa chowuma),
• mtima wamtima (kugunda kwamkati pamtima kumaphwanyidwa),
• urethra (chiwopsezo cha matenda osiyanasiyana, nocturia),
• thupi lawo siligwirizana (kuyabwa, redness, ming'oma, totupa).

Zofunika! Pamavuto oyamba amakumana ndi zovuta, munthu ayenera kusiya kumwa mankhwalawo ndipo ayenera kufunsa dokotala nthawi yomweyo.

Nthawi zina, wodwalayo amatha kudziwa payekha kuchuluka kwa mankhwalawa, omwe amayambitsa bongo. Momwe mungachite molondola, kuphwanya kumeneku kumabweretsa chiwonetsero chachikulu cha matenda:

• nseru
• kufooka
• kusanza
• kuphwanya chopondapo (kutsegula m'mimba, kudzimbidwa),
• mutu ndi chizungulire,
• kuthamanga kwa magazi kumachepa
• kuphipha mu bronchi.

Kuti abwezeretse thanzi la munthu, adokotala amalimbikitsa wodwala kuti alandire chithandizo china. Sambani m'mimba bwino ndikutsuka makala. Imwani madzi ambiri kuti mubwezeretse madzi m'thupi.

Zofunika! Kodi ndingatenge indapamide yopuma bwanji? Monga lamulo, mankhwalawa amaloledwa kumwa kwa miyezi iwiri. Komabe, adokotala angalimbikitse kumwa mapiritsi awa mosalekeza.

A diuretic ndi yoletsedwa kwa amayi apakati! Sizimachepetsa kutupa komanso sibwezeretsa kuthamanga kwa magazi pa nthawi yomwe muli ndi pakati. Yogwira pophika mankhwala imangovulaza kukula kwachilendo kwa mwana wosabadwayo. Zimayambitsa kuchepa kwa magazi, zomwe zimapangitsa kuti mwana wosabadwa ayambe kudekha.

Panthawi yoyamwitsa, Indapamide simalimbikitsidwa konse. Zigawo zonse za mapiritsiwa zimafalikira mwachangu mthupi lonse la mkazi ndipo zimakamizidwa mkaka wa m'mawere. Chifukwa chake, mankhwalawa amatha kulowa mkaka m'thupi la mwana wosalimba. Kuphwanya kumeneku kumakhudza kwambiri kukula kwa mwana.

Mukamadwala a diuretic Indapamide, zizindikiro zimawonedwa zomwe zikuwonetsa kuchepa kwa kuthamanga kwa magazi. Popeza izi, wodwalayo ayenera kukana kuyendetsa galimoto ndikugwira ntchito ndi zida.

Mtengo wa mankhwalawa umatengera zinthu zambiri, mwachitsanzo, wopanga, kuchuluka kwa mapiritsi omwe ali phukusi, komanso zomwe mzinda wina umachita. Pafupifupi, mtengo wa Indapamide umachokera ku 50-120 UAH.

Pharmacology yamakono imapanga mankhwala ambiri omwe ali ofanana ndikupanga komanso moyenera kukwaniritsa zomwe ali. Pabizinesi iliyonse, mungagule fanizo la mankhwala okodzetsa:

• Arifon Penga,
• Vasopamide, indabru,
• Indap, Indapamide,
• Indapen, Indapres,
• Indatens, M'nyumba,
• Lorvas, Ravel,
• Softenzin, Hemopamide.

Mwachidziwikire, pali mitundu yambiri yamankhwala, kotero mutha kusankha iliyonse ya iwo. Onsewa ali ndi gawo limodzi lomwelo. Kusiyana kwamakampani opanga mankhwala ndi zina zowonjezera za mankhwalawo.

Pharmacology yamakono imapanga mankhwala ambiri ogwira diuretic. Komabe, ndi uti angasankhe wobweretsa phindu lalikulu mthupi? Pansipa pali njira zina.

Indapamide Retard piritsi limodzi lili ndi 1.5 mg yogwira ntchito (indapamide). Mankhwalawa amabwezeretsa magazi komanso kulimbitsa makhoma amitsempha yamagazi. Indapamide Retard ilinso ndi contraindication ofananawo komanso zinthu zoyipa monga Indapamide. Kusiyanaku kumangokhala kuchuluka kwa zinthu zomwe zikugwira ntchito. Amapangidwa ku Russia.

Indap imapangidwa mu makapisozi, iliyonse yomwe ili ndi 2,5 mg pazomwe zimagwira kwambiri. Mankhwalawa ndi ofatsa okodzetsa, motero amalembedwa chifukwa cha matenda oopsa. Mankhwala ali ndi contraindication omwewo ndi zoyipa zimachitikira monga Indapamide. Amapangidwa ku Prague.

Verashpiron ndi wa potaziyamu wodzipulumutsa. Chofunikira chachikulu pa mankhwalawa ndi spironolactone (25 mg). Mankhwala ali ndi mitundu yambiri. Amagwiritsidwa ntchito poyerekeza matenda osokoneza bongo, edematous syndrome panthawi yolephera mtima, matenda a chiwindi, matenda a Conn. Contraindication ndi zovuta zimachitika ndizofanana ndi Indapamide. Wopanga Hungary.

Arifon amapangidwa m'mapiritsi, chilichonse chimakhala ndi 2,5 mg pazomwe zimagwira ntchito kwambiri (indapamide). Mankhwalawa ndi okodzetsa, chifukwa chake nthawi zambiri amalimbikitsidwa pakufunika kwa matenda oopsa. Milandu yayikulu yotsutsana komanso kusinthika kofanana ndizofanana ndi Indapamide. Wopanga France.

Pa mavuto aliwonse azaumoyo, ndikofunikira kukaonana ndi dokotala munthawi yake. Osadzilimbitsa nokha ndikusankha nokha mankhwala, njira izi zitha kungovulaza thupi lanu lomwe likudwala. Ndikofunika kudalira thanzi lanu kwa madokotala odziwa bwino omwe angasankhe chithandizo chamankhwala abwino ndikukhalanso ndi thanzi labwino.

Kwa omwe Indapamide adalembedwa

Odwala onse omwe ali ndi matenda oopsa amathanso kulandira chithandizo cha moyo wonse, chomwe chimakhala ngati munthu akumwa mankhwala tsiku lililonse. Mawu awa akhala asakufunsidwa m'magulu azachipatala akatswiri. Zinapezeka kuti kuwongolera kuthana ndimankhwala osachepera 2 nthawi kumachepetsa mwayi wamatenda amtima, kuphatikizapo oopsa. Palibe kutsutsana pamakakamizidwe oyambira kumwa mapiritsi. Padziko lonse lapansi, gawo lofunikira la odwala ambiri limawonetsedwa kuti ndi 140/90, ngakhale kuthamangitsidwa kukwera mosadukiza ndipo sikumayambitsa kusokonezeka kulikonse. Pewani kumwa mapiritsi okhawo ndi matenda oopsa. Kuti muchite izi, muyenera kuchepetsa thupi, kusiya fodya ndi mowa, kusintha zakudya.

Chizindikiro chokhacho chogwiritsira ntchito Indapamide chomwe chikuwonetsedwa mu malangizowo ndi matenda oopsa. Kuthamanga kwa magazi nthawi zambiri kumaphatikizidwa ndi matenda a mtima, impso, mitsempha yamagazi, chifukwa chake, mankhwala omwe amalembedwa kuti achepetse, amayenera kuyesedwa kuti atetezeke komanso agwire bwino ntchito m'magulu awa.

Zomwe zimathandiza Indapamide:

1. Kutsika kwapakati pa kupanikizika mukamatenga Indapamide ndi: kumtunda - 25, kutsika - 13 mm Hg
2. Kafukufuku adazindikira kuti ntchito ya antihypertensive ya 1.5 g ya indapamide ndiyofanana 20 mg ya enalapril.
3. Kupanikizika kwa nthawi yayitali kumabweretsa kuwonjezereka kwa ventricle yamtima. Kusintha kwa ma pathological kotereku kumakhala kodzaza ndi kusokonezeka kwa miyendo, kugunda, kulephera mtima. Mapiritsi a Indapamide amathandizira kuchepa kwa lamanzere yamitsempha yama cell, kuposa enalapril.
4. Kwa matenda a impso, Indapamide siigwira ntchito kwenikweni. Kuchita kwake kungaonedwe ndi kugwa kwa 46% pamlingo wa albumin mkodzo, womwe umawerengedwa ngati chimodzi mwazizindikiro zakulephera kwa impso.
5. Mankhwalawa alibe zotsatira zoyipa za shuga, potaziyamu ndi cholesterol yamagazi, chifukwa chake, angagwiritsidwe ntchito kwambiri kwa matenda ashuga.Kuthana ndi matenda oopsa mu diabetes, okodzetsa amapatsidwa mankhwala ochepa, osakanikirana ndi ACE inhibitors kapena Losartan.
6. Katundu wapadera wa Indapamide pakati pa okodzetsa ndiwowonjezera mulingo wa "wabwino" cholesterol wa HDL ndi pafupifupi 5.5%.

Kodi mankhwalawa amagwira ntchito bwanji?

Chuma chachikulu cha okodzetsa ndi kuwonjezeka kwa mkodzo. Nthawi yomweyo, kuchuluka kwamadzi mu minyewa ndi mitsempha yamagazi amatsika, ndipo kuthamanga kumachepa. M'mwezi wa chithandizo, kuchuluka kwamadzi am'mimba amayamba kuchepa ndi 10-15%, kulemera chifukwa cha kuchepa kwa madzi kumachepa pafupifupi 1.5 makilogalamu.

Indapamide pagulu lake limakhala malo apadera, madokotala amachitcha kuti diuretic popanda diuretic. Izi ndizovomerezeka pamalingaliro ang'onoang'ono. Mankhwalawa samakhudza kuchuluka kwa mkodzo, koma amakhala ndi kupuma kwamitsempha yamagazi pokhapokha atagwiritsidwa ntchito pa mlingo wa ≤ 2.5 mg. Ngati mutenga 5 mg, kutulutsa mkodzo kumawonjezeka ndi 20%.

Chifukwa cha kupsinjika komwe kumagwa:

1. Misewu ya calcium imatsekedwa, zomwe zimapangitsa kuchepa kwa kuchuluka kwa calcium m'makoma amitsempha, kenako ndikukulira kwamitsempha yamagazi.
2. Njira za potaziyamu zimayendetsedwa, motero, kulowa kwa calcium m'maselo kumatsika, kaphatikizidwe ka nitric oxide m'makoma amitsempha amakulirakulira, ndipo zombo zimapumira.
3. Kapangidwe ka prostacyclin kumakhudzidwa, chifukwa chomwe kuthekera kwa ma protein kupangira zigawo zamagazi ndikutsamira kumakoma amitsempha yamagazi kumachepa, ndipo kamvekedwe ka minofu ya makoma a mtima amachepa.

Kutulutsa mawonekedwe ndi mlingo

Mankhwala oyamba omwe ali ndi indapamide amapangidwa ndi Servier Pharmaceutical Company pansi pa dzina la Arifon. Kuphatikiza pa choyambirira cha Arifon, zamagetsi ambiri omwe ali ndi indapamide adalembetsedwa ku Russia, kuphatikiza pansi pa dzina lomwelo la Indapamide. Ma analogi a Arifon amapangidwa mwa mawonekedwe a makapisozi kapena mapiritsi okhala ndi filimu. Posachedwa, mankhwala osokoneza bongo omwe amasinthidwa a indapamide kuchokera pamapiritsi adadziwika.

Kodi Indapamide imapangidwa m'mitundu iti?

Malinga ndi akatswiri a mtima, ndikofunikira kugula Indapamide wamba mu makapisozi. Mankhwalawa amasungidwa m'mabotolo nthawi yayitali, ali ndi bioavailability yambiri, amakamizidwa mwachangu, ali ndi zinthu zochepa zothandizira, zomwe zikutanthauza kuti amayambitsa ziwengo pafupipafupi.

Mtundu wamakono kwambiri wa indapamide ndi mapiritsi okhala ndi nthawi yayitali. Zomwe zimagwira kuchokera kwa iwo zimamasulidwa pang'onopang'ono chifukwa chaukadaulo wapadera: kuchuluka kwa indapamide komwe kumagawidwa mothandizidwa ndi cellulose. Mukangolowa m'mimba, pang'onopang'ono cellulose imasanduka gel. Zimatenga pafupifupi maola 16 kuti matulani apaleti asungunuke.

Poyerekeza ndi mapiritsi amwambo wamba, indapamide yomwe imakhala nthawi yayitali imapereka mphamvu yokhazikika komanso yolimba ya antihypertensive, kusinthasintha kwa tsiku ndi tsiku pakudya pang'ono. Mwakulimba kwa kuchitapo kanthu, 2.5 mg ya wamba Indapamide ndi 1.5 mg kutalika. Zotsatira zoyipa zambiri zimadalira mlingo, ndiye kuti, kuchuluka kwawo komanso kuopsa kwake kumawonjezeka ndi kumwa mankhwala. Kutenga mapiritsi a Indapamide nthawi yayitali kumatha kuchepetsa chiopsezo cha mavuto, makamaka kutsika kwa magazi a potaziyamu.

Kusiyanitsidwa kwakutali kwa indapamide kumatha kukhala pa 1.5 mg. Phukusili likhale chizindikiro cha "zochita nthawi yayitali", "kusinthidwa kusinthidwa", "kutulutsidwa kolamulidwa", dzinalo likhoza kukhala ndi "retard", "MV", "long", "SR", "CP".

Momwe angatenge

Kugwiritsa ntchito indapamide kuti muchepetse kupanikizika sikutanthauza kuchuluka kwa pang'onopang'ono. Mapiritsi yomweyo amayamba kumwa muyezo. Mankhwalawa amadziunjikira m'magazi pang'onopang'ono, kotero ndizotheka kuweruza kugwira ntchito kwake pokhapokha sabata 1 la chithandizo.

Malamulo okuvomerezedwa kuchokera kuzomwe mungagwiritse ntchito:

Chonde dziwani: musanayambe chithandizo ndi diuretics iliyonse, ndikofunika kuwunika magawo ena a magazi: potaziyamu, shuga, creatinine, urea. Ngati zotsatira zoyeserera zikusiyana ndi zofunikira, funsani dokotala wanu, chifukwa kutenga mankhwala okodzetsa kumatha kukhala koopsa.

Ndingatenge nthawi yayitali bwanji osapuma

Mapiritsi oponderezedwa a Indapamide amaloledwa kumwa nthawi yopanda malire, malinga ndi momwe amapereka gawo lomwe akukakamizidwa ndipo amalekeredwa bwino, ndiye kuti, samayambitsa zovuta zomwe zimakhala zowononga thanzi. Osasiya kumwa mankhwalawo, ngakhale atakukakamizani kuti abwerere mwakale.

Osachepera 0,01% ya odwala matenda oopsa omwe amakhala ndi mapiritsi a Indapamide ndi mapiritsi ake, kusintha kwa kapangidwe ka magazi kumawonekera: kuchepa kwa leukocytes, mapulateleti, hemolytic kapena aplastic anemia. Kuti mupeze kuphwanya kwawoko panthawi yake, malangizowo amalimbikitsa kuti mukayezetse magazi miyezi isanu ndi umodzi iliyonse.

Indapamide, pamlingo wocheperako poyerekezera ena okodzetsa, amalimbikitsa kutulutsa kwa potaziyamu m'thupi. Komabe, odwala matenda oopsa omwe ali pachiwopsezo chogwiritsa ntchito mapiritsi nthawi yayitali amatha kukhala ndi hypokalemia. Zomwe zimayambitsa ngozi zimaphatikizapo ukalamba, matenda enaake, edema, matenda amtima. Zizindikiro za hypokalemia ndi kutopa, kupweteka kwa minofu. Mu kuwunika kwa odwala omwe adakumana ndi vutoli, amalankhulanso za kufooka kwambiri - "osagwira miyendo", kudzimbidwa pafupipafupi. Kupewera kwa hypokalemia ndiko kumwa zakudya kwambiri zam potaziyamu: nyemba, masamba, nsomba, zipatso zouma.

Zotsatira zoyipa

Zochita zosafunikira za Indapamide ndi pafupipafupi zomwe zimachitika:

Doctor of Medical Science, Mutu wa Institute of Diabetesology - Tatyana Yakovleva

Ndakhala ndikuphunzira matenda a shuga kwa zaka zambiri. Zimakhala zowopsa anthu ambiri akamwalira, ndipo makamaka amakhala olumala chifukwa cha matenda ashuga.

Ndithamangira kunena mbiri yabwino - Endocrinological Research Center ya Russia Academy of Medical Science idatha kupanga mankhwala omwe amachiritsiratu matenda ashuga. Pakadali pano, kugwiritsa ntchito bwino kwa mankhwalawa kuyandikira 98%.

Nkhani ina yabwino: Unduna wa Zaumoyo wateteza kukhazikitsidwa kwa pulogalamu yapadera yomwe imalipira mtengo wa mankhwalawo. Ku Russia, odwala matenda ashuga mpaka Meyi 18 (kuphatikiza) nditha kuipeza - Kwa ma ruble 147 okha!

Malangizo ogwiritsira ntchito akuwonetsa kuti kuthekera kwa kusokonezeka kwakutali ndikwachulukidwe ndi mapiritsi a Indapamide, otsika ngati mukugwiritsa ntchito fomu yayitali.

Contraindication

Mndandanda wamilandu ya Indapamide ndi yochepa kwambiri. Mankhwala sangathe kumwa:

• ngati chimodzi mwa zinthu zake chikukhumudwitsa,
• chifukwa ziwengo kuti sulfonamide zotumphukira - nimesulide (Nise, Nimesil ndi ena), celecoxib (Celebrex),
• wamphamvu ndi aimpso kapena kwa chiwindi,
• ngati mungakhazikitse hypokalemia,
• ndi hypolactasia - mapiritsi ali ndi lactose.

Mimba, ubwana, kuyamwitsa sizimaganiziridwa kuti ndi contraindication. Muzochitika izi, kumwa Indapamide sikofunikira, koma ndikotheka poika komanso moyang'aniridwa ndi dokotala.

Malangizo ogwiritsira ntchito Indapamide sakusonyeza kuti akhoza kumwa ndi mowa. Komabe, mu malingaliro a madotolo, kuyenderana kwa mowa ndi mankhwalawa kumawonetsedwa kuti ndi owopsa thanzi. Kugwiritsidwa ntchito kamodzi kwa ethanol kumatha kugwetsa mavuto. Kuchitiridwa nkhanza pafupipafupi kumawonjezera chiopsezo cha hypokalemia, kumachepetsa mphamvu ya Hypotensive.

Analogs ndi choloweza

Mankhwalawa amabwerezedwanso m'mapiritsi ndi muyezo, ndiye kuti, mankhwala otsatirawa omwe adalembedwa ku Russian Federation ali ndi chithunzi chonse cha Indapamide:

Zitha kusintha m'malo mwa Indapamide popanda kuonana ndi adokotala. Malinga ndi ndemanga ya odwala omwe amamwa mankhwalawo, apamwamba kwambiri pamndandandawu ndi mapiritsi a Arifon ndi Indap.

Yerekezerani ndi mankhwala ofanana

Pakati pa thiazide ndi thiazide-ngati diuretics, indapamide imatha kupikisana ndi hydrochlorothiazide (mankhwala Hydrochlorothiazide, Hypothiazide, Enap compact, Lorista ndi mankhwala ena ambiri a antihypertensive) ndi chlortalidone (mapiritsi a Oxodoline, amodzi mwa magawo a Tenorik ndi Tenoretik).

Zofanana poyerekeza ndi mankhwalawa:

• mphamvu ya 2.5 mg ya indapamide ndi ofanana 25 mg ya hydrochlorothiazide ndi chlortalidone,
• hydrochlorothiazide ndi chlortalidone sizingakhale m'malo mwa indapamide mu matenda a impso. Amadziwitsidwa kuti impso zisasinthidwe, motero, ndi kulephera kwa aimpso, bongo ndiwotheka kwambiri. Indapamide imapangidwa ndi chiwindi, osapitilira 5% amachotsedwa mu mawonekedwe othandizira, motero amatha kuledzera mpaka pakulephera kwakukulu kwa impso,
• Poyerekeza ndi hydrochlorothiazide, indapamide imateteza kwambiri impso. Pazaka 2 za kumwa, GFR imawonjezeka ndi 28%. Mukamamwa hydrochlorothiazide - yochepetsedwa ndi 17%,
• chlortalidone imatenga masiku atatu, motero imatha kugwiritsidwa ntchito mwa odwala omwe sangathe kumwa mankhwalawo pawokha,
• Mapiritsi a Indapamide samakhudza kagayidwe kazakudya, chifukwa chake amatha kugwiritsidwa ntchito pa matenda ashuga. Hydrochlorothiazide imathandizira kukana insulin.

Pharmacodynamics ndi pharmacokinetics

Mwa mankhwala ake, mankhwalawa ali pafupi thiazide okodzetsa. Kuchulukitsa ndende ya sodium, chlorine, potaziyamu ndi magnesium ion mu mkodzo. Kuchulukitsa kutalika kwa makoma a mitsempha, pang'onopang'ono kumachepetsa kukana kwa zotumphukira. Sizikhudza chakudya kagayidwe kachakudya komanso okhutira lipids m'magazi, amathandizira kuchepetsa lamanzere lamitsempha lamanzere.

Indapamide ndichinthu chothandiza kupanga prostaglandin E2, ili ndi gawo lalikulu pakupanga ma free oxygen oxygen radicals.

Mankhwalawa amayamba kuchita mphindi 30 pambuyo pa kukonzekera (bioavailability pafupifupi 93%), achire zotsatira zimapitirira tsiku limodzi. Kuzindikira kwakukulu m'magazi ndi maola 12 piritsi litasungunuka m'mimba. Kutha kwa theka-moyo ndi maola 18. Kudya kungakulitse kucheperako nthawi, koma mankhwalawo, umakhudzidwa kwathunthu. Impso zimakhazikika mpaka 80% ya zinthuzo metabolitesmatumbo - mpaka 20%.

Zotsatira zoyipa

Mankhwala, monga diuretic, angayambitse kuchepa kwa seramu potaziyamu, kutsika kwa sodium ndende, komwe kumabweretsa kuchepa thupi. Pankhaniyi, zizindikiro monga kamwa yowuma, kudzimbidwa, nseru, mutu, thupi lawo siligwirizana.

Zotsatira zoyipa - kutentha kwa mtima, hemolytic anemia.

Mapiritsi a Indapamide, malangizo ogwiritsira ntchito

Mapiritsi amatengedwa mosamalitsa mogwirizana ndi malangizo - kamodzi patsiku, makamaka m'mawa, piritsi limodzi kapena kapisozi.

Mankhwalawa amatha kuphatikizidwa ndi mankhwala ena a antihypertensive, koma ndi adokotala okhawo omwe amatha kudziwa momwe angamwe mankhwalawo mosiyanasiyana.

Malangizo ogwiritsira ntchito Indapamide Retard ndi malangizo ogwiritsira ntchito Indapamide MV Stad (opangidwa ku Germany) mulibe zosiyana zokhudzana ndi momwe kayendetsedwe ndi kayendetsedwe kamankhwala zimayendera. Komabe, mankhwalawa Bweretsani Amadziwika ndi nthawi yayitali, ndipo, nthawi yomweyo, kuchititsa kufatsa kwa reagent, chifukwa chakumasulidwa pang'onopang'ono kwa chinthu chogwira ntchito.

Ndingatenge nthawi yayitali bwanji Indapamide, adokotala asankha, kupatsidwa gawo matenda oopsa, koma muzochita zamankhwala mankhwala awa amatanthauza mankhwala omwe amalembedwa nthawi yayitali (kuphatikiza nthawi ya moyo).

Bongo

Kuopsa kwa mankhwalawa kumawonekera pa 40 mg. Zizindikiro za poizoni - kugona, nseru, kusanza, lakuthwa kukhumudwa, kamwa yowuma.

Njira zodalirika - kukonzanso kwa chapamimba, kubwezeretsa bwino kwa electrolyte, kupewanso madzi m'thupi (kokha mu chipatala).

Kuchita ndi mankhwala ena

• Ma antidepressants ndi ma antipsychotic amalimbikitsa hypotensive zotsatira, kuwonjezera mwayi wakukula orthostatic hypotension.
• Aluretics, mtima glycosides, mankhwala ofewetsa tuvi tomwe timawonjezera ngozi potaziyamu.
• Erythromycin kumatha kubweretsa chitukuko tachycardia ndi michere yamitsempha yamagazi.
• Mankhwala osagwiritsa ntchito mankhwala osokoneza bongo, glucocorticosteroids amachepetsa mphamvu ya hypotensive.
• Kukonzekera komwe kuli ayodinizingayambitse kusowa kwamadzi m'thupi.
• Cyclosporin amalimbikitsa chitukuko hypercreatininemia.

Analogs a Indapamide

Mankhwala ofanana: Indapen, Lorvas, Acrylamide, Zosangalatsa, Hydrochlorothiazide, Oxodoline, Chizungu.

Indapamide ndi mayendedwe ake amatengedwa mosamalitsa monga adanenera dokotala.

Ndemanga za Indapamide

Ndemanga za Indapamide retard, ambiri, amawonetsa kuti mankhwalawa amagwira ntchito kwambiri. Odwala othamanga, ambiri, amalekerera bwino mankhwala.Ndemanga za madotolo ndi odwala, komanso malo omwe pamafotokozedwera chithandizo chamankhwala ogwirizana, amatsimikizira izi motsimikiza.

Zotsatira zoyipa ndizosowa, ndipo zimadziwika ndi kufooka kofooka. Anthu ambiri opezeka ndi matenda oopsa amathanso mapiritsi amoyo.

Zochokera pa intaneti

Munthawi ya chithandizo chovuta kwambiri cha matenda oopsa, dokotala amayenera kupereka okodzetsa, popeza kuthamanga kwa magazi kumachepetsa mwachangu ndi kutulutsa kwamadzi m'thupi. Makampani opanga mankhwala apanga mankhwala ambiri okodzetsa. Nthawi zambiri, ngati pali edema, dokotala amalembera Indapamide kuti akapanikizike. Komabe, mankhwalawa ali ndi contraindication komanso mawonekedwe ogwiritsira ntchito, chifukwa chake amafunika kugwirizanitsa chithandizo ndi dokotala.

Mtengo wa Indapamide, komwe mungagule

Mtengo umachokera ku ruble 26 mpaka 170 phukusi lililonse.

Mtengo Indapamide retard - kuchokera ku ruble 30 mpaka 116 (mtengo wa kudalira ndondomeko yamitengo yamitolo yamankhwala, ndi wopanga).

Mtengo wa mapiritsi Indapamide Retard-Teva Kutulutsidwa kwamphamvu kwa chinthu, pafupifupi, kwapamwamba kuposa mankhwala omwe ali ndi chizolowezi chochita.

Ntchito Indapamide monga mankhwala a kuthamanga kwa magazi.

Moni okondedwa, komanso ogwiritsa ntchito tsamba la Otzovik. Kuthamanga kwa magazi ndi vuto losatha komanso matenda m'mabanja mwanga. Pali mankhwala ambiri omwe amalimbana ndi izi kotero kuti nthawi zina mumatha kusokonezeka mwa iwo. O ...

Yogwira ntchito komanso yotsika mtengo

Othandizira a antihypertensive nthawi zina amafunika kusinthidwa, chifukwa thupi limazolowera, ndipo mankhwalawo amasiya kugwira ntchito pakapita nthawi. Posachedwa, ndakhala ndikutenga indapamide chifukwa cha kuthamanga kwa magazi. Piritsi limodzi mutatha kudya komanso bwino, kupanikizika ndikwabwinobwino. Zotsatira zoyipa za ...

ambiri amathandizira kuchepa kwa magazi

sikuti nthawi zonse kumakhala kukakamira

Mankhwalawa adandizindikira chifukwa adalamulidwa kalekale ndi wochita zam'deralo kuti apanikizidwe ndi mawu. Pazonse, onse a mtima ndi wowerengeka adapereka mankhwala osiyanasiyana okhudzana ndi matenda a kukakamizidwa ...

Amachepetsa kupanikizika, ofatsa okodzetsa, amatenga nthawi 1 yokha patsiku, kupezeka kwa mankhwalawa

Zimathandizira ndi kukakamiza kosaposa 150/80,

Mayi anga ali ndi matenda oopsa. Matendawa ndi owopsa, koma mpaka posachedwapa, ine, ndikuwawona amayi anga pafupifupi tsiku lililonse, sindinawone momwe amakhudzira thupi, kupatula kungopweteka mutu, komwe amayi anga amadandaula nthawi ndi nthawi. Komabe, m'chilimwe panali zochitika zomwe ...

kupsinjika kwanga sikunakuwonjezeke chifukwa cha matenda oopsa, koma chifukwa cha michere ya dystonia yamasamba, kotero indapamide siyinakukwanire, kapena m'malo mwake ndidachira! Kupsinjika kunatsika kwambiri, ndipo mtima unachepa kwambiri. Ngakhale sindine ...

Kutsika mtengo, kosavuta kutenga

sizinakwaniritse, kupweteka mutu

Dongosolo lotsika mtengo lotere nthawi zambiri limayikidwa ndi madokotala. Indapamide ndizosavuta kutenga piritsi 1 nthawi imodzi patsiku, ngakhale zakudya. Amasonyezedwa kwa matenda oopsa. Pali zovuta zambiri pamalangizo, koma zikuwonekeratu kuti izi palibe ...

wotsika mtengo komanso wogwira ntchito, osati ngati okodzetsa

onani potaziyamu ndi magnesium mukamamwa mankhwalawa

Osachepera kwa ine. Mankhwalawa adandipatsa mankhwala ochepetsa mphamvu ya ma hydronephrosis anga. Zinachitika kuti kunali kofunika kumwa china chake. Pempho langa, madokotala amafunikira - otsika mtengo, okhala ndi zovuta zochepa ...

Mayi anga ali ndi vuto la kuthamanga magazi. Kupanikizika kwambiri kumatulukanso chifukwa cha kusayenda kwamadzi mthupi. Edema nayenso amachokera pamenepa. Ndipo mu nduna yake ya zamankhwala nthawi zonse amakhala ndi okodzetsa a Indapamide. Dotolo adamuuza kuti amwe 1 ...

Mankhwala otsika mtengo, othandiza.

Mankhwalawa ayenera kukhala okwanira, ndi yekhayo amene sangathe kuthandiza

Zidachitika kuti mu 40s ndidaphunzira kuti kuthamanga kwambiri. Sindimaganiza kuti izi zitha kundichitikira.Ndimatsatira zakudya zoyenera, ndimakhala ndi moyo wakhama, nditakhala pansi ...

Diuretic, imathandiza kuchepetsa kuthamanga kwa magazi, imawononga ndalama.

Mtengo wotsika, kutsitsa magazi, okodzetsa

The diuretic zotsatira sizichitika mwachangu

Makolo anga amatenga diuretic iyi "Indapamide" pa kukakamizidwa kwambiri. Imwani piritsi limodzi la 2,5 mg kamodzi patsiku. Ngati mumamwa m'mawa, ndiye kuti diuretic zotsatira zimayamba usiku. Choyipa chake ndikuti chimasokoneza ...

Milandu yambiri.

Okondedwa owerenga, moni! Chifukwa chake ndidasankha kulemba ndemanga pa Indapamid. Mwamuna wanga adadwala matenda a mtima chaka chatha, ali ndi matenda ashuga, komanso matenda oopsa. Dotolo adamupatsa mankhwala, kuphatikizapo ena, kuphatikizapo mitroformin ...

pali zotsutsana ndi zoyipa.

Sindikumutcha kuti wokodzetsa. Zowonadi, kukhala zenizeni, indapamide ndi diuretic. Koma mu gawo lotere, lomwe limagwiritsidwa ntchito pamapiritsi awa, zomwe zikuyembekezeredwa kuchokera ku izi zimatithandizanso antihypertensive ndi vasodilator ...

Imakulitsa nthawi yogonana.

Sindinagwiritsepo ntchito ma diuretics m'moyo wanga (osaphatikizira m'chiuno cha rose), koma ndiye ndidaphunzira za chimodzi mwazinthu zosangalatsa zomwe amagwiritsa ntchito amuna. Sindikudziwa tsatanetsatane wamakanidwewo, koma kugwiritsa ntchito zododometsa kumakupatsani mwayi wowonjezera nthawi yogonana, "kukankha" kwa ena ...

Monga mankhwala onse.

Mankhwala a antihypertensive Indapamide ali ndi okodzetsa ena. Indapamide imakhala ndi vuto lochepetsa muyezo womwe ulibe kutulutsa mphamvu. Imagwira anthu omwe ali ndi impso imodzi. Pogwiritsa ntchito pafupipafupi, zotsatira za hypotensive za Indapamide zimakhazikika mu masabata 1-2, zimafika ...

Imachepetsa bwino kupanikizika, imachepetsa kutupa, ndipo mtengo wake ndi wotsika mtengo.

Mankhwalawa siokwera mtengo, indedi pamakhala zovuta zina, ndimayitenga, chifukwa cha edema, vuto langa ndilakuti, miyendo yanga idatupa kwambiri, makamaka nthawi yotentha kutentha, m'mawa pamimba yopanda piritsi 1 patsiku, koma ndimamwa Aspark ...

Ma diuretics kapena okodzetsa. Lero ndikufuna kukuwuzani za indapamide. Osati mankhwala omwe ndimakonda. Koma othandiza. Chizindikiro chokhacho cha mankhwalawa ndi matenda oopsa (kuthamanga kwa magazi). Ndidatenga pomwe ndidatupa ...

Kwa nthawi yoyamba ndinali ndi vuto la matenda oopsa, chikhalidwe chosasangalatsa, yemwe anali ndi nkhawa amandimvetsa.

Wothandizira pakusintha kwamankhwala omwe ndimamwa kale kuchokera ku kukakamiza komwe kumayikidwa Indapamide.

Ndakhala ndikumwa kwa sabata limodzi, ndimamwa tsiku lililonse, piritsi limodzi m'mawa.

Lero adalinso pa nthawi yoika othandizira, adauza adotolo kuti sindikumvanso kuti ndiwothandiza.

Anandifotokozera kuti popeza ndimapanikizika koyamba, ndimazolowera mankhwalawa ndipo zimakhudza tsiku ndi tsiku, zimapangitsa kuti akhutire pang'ono.

Koma ndikumva kufooka, koma sindikumvetsa ngati mankhwalawa andipatsanso zoyipa zake? Ndidasintha mankhwala angapo, komabe sindimamvetsetsa.

Malinga ndi kufotokozera ndi kuwunika, mankhwalawa si oyipa. Kumwa kumatanthauza kumwa, ine mwina sindingakhale mwa njira ina.

Indapamide ndiyotsika mtengo kwenikweni ndipo malinga ndi ndemanga yothandiza kwambiri. Koma tonse ndife amodzi. M'mawonekedwe amodzi ndidawerengapo kuti sanakhudzidwe ndi kupukusa mafuta ...

Zaka 2, miyezi 10 yapitayo Rathone

Othandizira a antihypertensive nthawi zina amafunika kusinthidwa, chifukwa thupi limazolowera, ndipo mankhwalawo amasiya kugwira ntchito pakapita nthawi. Posachedwa ndakhala ndikutenga indapamide chifukwa cha kuthamanga kwa magazi ....

Zaka 2, miyezi 11 yapitachi Osonkhana

Amayi anga ali ndi matenda oopsa, kuthamanga kwa magazi, adapita kwa dotolo, adotolo adalemba mankhwala a indapamide ndi mankhwala ena a antihypertensive, omwe amathandizidwa kwakanthawi ...

Zaka 3 zapitazo Kukwera

Mayi anga ali ndi vuto la kuthamanga magazi. Kupanikizika kwambiri kumatulukanso chifukwa cha kusayenda kwamadzi mthupi. Edema nayenso amachokera pamenepa. Ndipo nthawi zonse amakhala ndi diu ku cabinet yake yamankhwala ...

Zaka 3, mwezi umodzi wapitawu Peacego

Indapamide adavomerezedwa ndi katswiri wamitsempha kuti achulukitse kuthamanga kwa magazi. Malangizo pazomwe zikugwiritsidwa ntchito akunena choncho: ochepa matenda oopsa. Indapam ...

Zaka 3, mwezi umodzi wapitawu Closenty

Mkazi wanga amakhala ndi mavuto opsinjika, amakhala ndi mantha pang'ono kapena kusintha kwa nyengo, mutu umawonekera ndipo tonometer imatiwonetsa kuti kupsinjika kukuwonjezeka. Nthawi ina anali ...

Zaka 3, miyezi iwiri yapitayo

Posachedwa, mkazi wanga anayamba kuda nkhawa ndi zipsinjo. Atatembenukira kuchipatala, adotolo adamupatsa mankhwala okodzetsa. Imagulitsidwa kuma CD a makatoni pamtengo ...

Zaka 3, 3 miyezi yapitayi Actumnanion

Dongosolo lotsika mtengo lotere nthawi zambiri limayikidwa ndi madokotala. Indapamide ndizosavuta kutenga piritsi 1 nthawi imodzi patsiku, ngakhale zakudya. Amasonyezedwa kwa matenda oopsa. ...

Zaka 3, miyezi 3 yapitayo

Sindinadziwe za mankhwalawa mpaka ndinayamba kudwala matenda a mtima. Katswiri wamtima adandiuza kuti ndisamapange chithandizo chovuta kuchipatala. Izi ...

Zaka 3, miyezi 3 yapitayo

Ma diuretics kapena okodzetsa. Lero ndikufuna kukuwuzani za indapamide. Osati mankhwala omwe ndimakonda. Koma othandiza. Chizindikiro chokha cha mankhwalawa ndi ...

Zaka 3, miyezi 4 yapitayo Strewel

Mankhwalawa siokwera mtengo, inde pali zovuta zoyipa, ndimatengera, ndi edema, vuto langa ndilakuti, miyendo yanga idatupa kwambiri, makamaka nthawi yotentha kutentha, m'mawa piritsi lopanda kanthu 1 p ...

Zaka 3, miyezi 4 yapitayo Growfallow

Mwamuna wanga ataganiza zoyamba kusintha mapiritsi anga otchedwa Amlodipine (sindinalembebebe za iwo?). Poyamba ndinasangalala ndi zotsatirapo zake. Mapiritsi amathandizadi ...

Zaka 3, miyezi 10 yapitayo Lemberani

Ndimatenga indapaimide pachaka ngati othandizira ena. Izi zisanachitike, ndinayesanso mankhwala ena angapo kwa nthawi yayitali. Zonsezi sizinali zoyenera chifukwa cha zovuta zambiri ...

Zaka 3, miyezi 10 yapitayo Devoursels

kupsinjika kwanga sikunakuwonjezeke chifukwa cha matenda oopsa, koma chifukwa cha michere ya dystonia yamasamba, kotero indapamide siyinakukwanire, kapena m'malo mwake ndidachira! Kupanikizika kwachepa ...

Zaka 4, miyezi 3 yapitayo Guartlyinger

Indapamide, ndakhala ndikumwa 2.5 mg kwa nthawi yayitali, amandithandiza bwino. Ndili ndi matenda oopsa. Mankhwala amachepetsa kutupa ndipo amachepetsa kupanikizika. Tengani bwino - nthawi 1 m'mawa. Osachulukitsa ...

Zaka 4, miyezi 4 yapitayo Saturnere

Osachepera kwa ine. Mankhwalawa adandipatsa mankhwala ochepetsa mphamvu ya ma hydronephrosis anga. Zinachitika kuti kunali kofunika kumwa china chake. M'malingaliro anga ...

Zaka 4, miyezi 5 yapitayo Wheelle

Ndinagula mankhwala ndi wachibale. amadwala matenda oopsa a digiri yoyamba. Mankhwalawa anali okwera mtengo, mosiyana ndi mankhwala ena a gulu lomweli ...

Zaka 4, miyezi 7 zapitazo Omangidwa

Mankhwala a antihypertensive Indapamide ali ndi okodzetsa ena. Indapamide imakhala ndi vuto lochepetsa muyezo womwe ulibe kutulutsa mphamvu. Ndiwothandiza ...

Zaka 4, miyezi 8 yapitayo Mastim

Sindinagwiritsepo ntchito ma diuretics m'moyo wanga (osaphatikizira m'chiuno cha rose), koma ndiye ndidaphunzira za chimodzi mwazinthu zosangalatsa zomwe amagwiritsa ntchito amuna. Sindikudziwa tsatanetsatane wa limagwirira, koma…

Zaka 4, miyezi 10 yapitayo Marambs

Nthawi zina mavuto amakwera, makamaka otsika. Tsopano tili ndi madzi oundana madigiri 40, motero thupi limakhudzana. Ndimamwa mankhwala ofunikira nthawi zonse. Kodi ...

Matenda olembetsa magazi komanso kukakamizidwa kukhala zinthu zakale - zaulere

Matenda a mtima komanso mikwingwirima ndizomwe zimayambitsa pafupifupi 70% ya imfa zonse padziko lapansi. Anthu asanu ndi awiri mwa anthu khumi amafa chifukwa chotseka mitsempha ya mtima kapena ubongo. Pafupifupi nthawi zonse, chifukwa chakumapeto kowopsa ndichofanana - kuthamanga kwa magazi chifukwa cha matenda oopsa.

Ndizotheka komanso kofunikira kuti muchepetse kukakamizidwa, osatero ayi. Koma izi sizichiritsa matendawa, koma zimangothandiza kulimbana ndi kufufuza, osati zomwe zimayambitsa matendawa.

Mankhwala okhawo omwe amalimbikitsidwa mwapadera kuti athandizire matenda oopsa ndipo amagwiritsidwanso ntchito ndi akatswiri a mtima pantchito yawo ndi a NORMIO.

Kugwiritsa ntchito bwino kwa mankhwalawa, kuwerengera malinga ndi njira yokhazikika (kuchuluka kwa odwala omwe achiwonjezere kuchuluka kwa odwala omwe ali pagulu la anthu 100 omwe adachitiridwa chithandizo):

• Matenda a kukakamizidwa - 97%
• Kuthetsa kwa mitsempha thrombosis - 80%
• Kuthetsa kwa kugunda kwamtima kwamphamvu - 99%
• Kuchotsa mutu - 92%
• Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku - 97%

Opanga a NORMIO si gulu lazamalonda ndipo amalipidwa ndi chithandizo cha boma. Chifukwa chake, tsopano aliyense wokhala ndi mwayi wopeza phukusi la mankhwalawa KWAULERE.

Kodi Indapamide imapangidwa m'mitundu iti?

Indapamide - malangizo, ntchito, ndemanga, mapiritsi, 2,5 mg ndi 1.5 mg ya retard, MV ndi Stad, makapisozi a 2,5 mg Verte

Munkhaniyi, mutha kuwerengera malangizo ogwiritsira ntchito mankhwalawa Indapamide. Amapereka ndemanga kuchokera kwa alendo omwe amabwera patsamba lino - ogwiritsa ntchito mankhwalawa, komanso malingaliro a akatswiri azachipatala pakugwiritsa ntchito diuretic Indapamide machitidwe awo. Chopempha chachikulu ndikuti muwonjezere ndemanga zanu za mankhwalawa: mankhwalawo adathandizira kapena sanathandizire kuchotsa matendawa, ndizovuta ziti zomwe zimawoneka ndi zotsatirapo zake, zomwe mwina sizinalengezedwe ndi wopanga. Ma Analogs a Indapamide pamakhala ma analogues omwe amapezeka. Ntchito mankhwalawa matenda oopsa mu akulu, ana, komanso pa nthawi yoyembekezera. Zimatenga nthawi yayitali bwanji kumwa mankhwalawa.

Indapamide - antihypertensive agent, thiazide-ngati okodzetsa mwamphamvu komanso mphamvu yayitali, benzamide yotengeka. Imakhala ndi zolimbitsa modabwitsa komanso zosakanikirana, zomwe zimalumikizidwa ndi kuphatikizika kwa sodium, chlorine, maayoni a hydrogen, komanso gawo lochepera la potaziyamu mu proximal tubules ndi gawo lozungulira la distal tubule ya nephron. Zotsatira za vasodilating ndi kuchepa kwa zotumphukira zamitsempha zonse zimatsutsana ndi njira zotsatirazi: kuchepa kwa kukhazikikanso kwa khoma lamitsempha kupita ku norepinephrine ndi angiotensin 2, kuwonjezeka kwa kaphatikizidwe ka ma prostaglandins omwe ali ndi ntchito ya vasodilator, komanso kuletsa kwa kashiamu kulowa m'makoma osalala amitsempha yamagazi.

Imachepetsa kamvekedwe ka minofu yosalala ya mitsempha, kumachepetsa kuphatikizira kwamitsempha yamagazi. Zimathandizira kuchepetsa kumanzere kwamitsempha yam'mimba. Mu mankhwalawa achire, sizimakhudza metabolidi ya lipid ndi carbohydrate (kuphatikiza odwala omwe ali ndi matenda a shuga a mellitus).

Mphamvu ya antihypertensive imayamba kumapeto kwa sabata loyamba / loyamba la sabata lachiwiri ndikumagwiritsa ntchito mosalekeza ndipo limatha kwa maola 24 motsutsana ndi gawo limodzi la mankhwala.

Pharmacokinetics

Pambuyo pakukonzekera pakamwa, imatengedwa mwachangu komanso kwathunthu kuchokera m'mimba, bioavailability ndi yayikulu (93%). Kudya pang'onopang'ono kumachepetsa mayamwidwe, koma sizikhudza kuchuluka kwa zinthu zotengeka. Ili ndi kuchuluka kwakukulu kogawa, kudutsa zolepheretsa za histoeticological (kuphatikizapo placental), kudutsa mkaka wa m'mawere. Wopangidwira m'chiwindi. 60-80% imachotsedwa ndi impso mu mawonekedwe a metabolites (pafupifupi 5% imachotsedwa osasinthika), kudzera m'matumbo - 20%. Odwala omwe ali ndi vuto la impso, ma pharmacokinetics sasintha. Sichikupanga.

Zizindikiro

Kutulutsa Mafomu

2.5 mg mapiritsi okhala ndi mafilimu.

Mapiritsi okhala ndi 2,5 mg Stad.

1.5 mg mapiritsi okhala ndi mapiritsi a Indapamide MV.

1.5 mg achigonjetse mapiritsi.

Makapisozi 2,5 mg Werth.

Malangizo ogwiritsira ntchito ndi mtundu wa mankhwala

Mapiritsi amatengedwa pakamwa popanda kutafuna. Mlingo wa tsiku ndi tsiku ndi piritsi limodzi (2,5 mg) patsiku (m'mawa). Ngati pambuyo pa masabata 4-8 a mankhwala othandizira ofunikirawa sakukwaniritsidwa, osavomerezeka kuti muwonjezere mlingo wa mankhwalawa (chiopsezo chowonjezereka cha zotsatira zoyipa popanda kupititsa patsogolo anti-hypertensive effect).M'malo mwake, tikulimbikitsidwa kuti mankhwala ena a antihypertensive omwe si okodzetsa aphatikizidwe mu regimen ya mankhwala.

Milandu yomwe chithandizo chiyenera kuyamba ndi mankhwala awiri, mlingo wa Indapamide umakhalabe pa 2,5 mg kamodzi patsiku m'mawa.

Mkati, osafuna kutafuna, mumamwa madzi amadzimadzi ambiri, mosasamala kanthu za kudya, makamaka m'mawa pa 1.5 mg (piritsi 1) patsiku.

Ngati pambuyo pa masabata 4-8 a mankhwala othandizira ofunikirawa sakukwaniritsidwa, osavomerezeka kuti muwonjezere mlingo wa mankhwalawa (chiopsezo cha zotsatira zoyipa chimawonjezeka popanda kukulitsa mphamvu ya antihypertensive). M'malo mwake, tikulimbikitsidwa kuti mankhwala ena a antihypertensive omwe si okodzetsa aphatikizidwe mu regimen ya mankhwala. Milandu yomwe chithandizo chiyenera kuyamba ndi mankhwala awiri, mlingo wa Indapamide retard umakhalabe wofanana ndi 1.5 mg kamodzi patsiku m'mawa.

Okalamba odwala, plasma ndende ya creatinine iyenera kulamulidwa poganizira zaka, kulemera kwa thupi ndi jenda, mankhwalawa amatha kugwiritsidwa ntchito mwa odwala okalamba omwe ali ndi vuto laimpso labwinobwino kapena pang'ono.

Zotsatira zoyipa

• kusanza, kusanza,
• kukomoka
• kamwa yowuma
• gastralgia,
• kutsegula m'mimba
• kudzimbidwa
• asthenia
• mantha
• mutu
• chizungulire
• kugona
• kusowa tulo
• kukhumudwa
• kutopa,
• kufooka wamba
• malaise
• kuphipha kwamisempha
• kusakhazikika
• conjunctivitis
• kuwonongeka kwamawonekedwe
• kutsokomola
• pharyngitis
• sinusitis
• rhinitis
• orthostatic hypotension,
• arrhasmia,
• kugunda kwa mtima
• nocturia
• polyuria
• zotupa
• urticaria
• kuyabwa
• hemorrhagic vasculitis,
• hyperglycemia, hypokalemia, hypochloremia, hyponatremia, hypercalcemia,
• chimfine ngati matenda
• kupweteka pachifuwa
• kupweteka kumbuyo
• utachepa potency
• yafupika libido
• Rhinorrhea
• thukuta
• kuwonda
• akumwetulira miyendo.

Contraindication

• anuria
• hypokalemia
• hepatic kwambiri (kuphatikizapo ndi encephalopathy) ndi / kapena kulephera kwaimpso,
• mimba
• kuyamwa
• zaka mpaka 18 - (kuchita bwino ndi chitetezo sizinakhazikitsidwe),
• kugwiritsa ntchito munthawi yomweyo mankhwala omwe amakulitsa nthawi ya QT,
• Hypersensitivity mankhwala ndi zina zotumphukira sulfonamide.

Mimba komanso kuyamwa

Contraindified mu mimba ndi mkaka wa m`mawere.

Malangizo apadera

Odwala omwe amatenga mtima glycosides, mankhwala ofewetsa thukuta, motsutsana ndi maziko a hyperaldosteronism, komanso okalamba, kuwunika pafupipafupi zomwe zili ndi potaziyamu ayoni ndi creatinine kumawonetsedwa.

Mukumwa mankhwala a indapamide, kuchuluka kwa potaziyamu, sodium, magnesium m'magazi am'magazi (kusokonezeka kwa elekitirogirisi kumatha kuchitika), pH, kuchuluka kwa glucose, uric acid ndi nitrogen yotsalira kuyenera kuyang'aniridwa mwadongosolo.

Kuwongolera kosamala kwambiri kumawonetsedwa kwa odwala omwe ali ndi vuto la cirrhosis (makamaka ndi edema kapena ascites - chiopsezo chokhala ndi metabolic alkalosis, chomwe chimawonjezera chiwonetsero cha hepatic encephalopathy), matenda a mtima, kuperewera kwa mtima, komanso okalamba. Gulu lomwe likuwopseza limaphatikizanso odwala omwe ali ndi nthawi yayitali ya QT pa electrocardiogram (wobadwa mwatsopano kapena kukulira motsutsana ndi maziko a njira iliyonse ya pathological).

Muyeso woyamba wa kuchuluka kwa potaziyamu m'magazi uyenera kuchitika sabata loyamba la chithandizo.

Ngati okodzetsa ndi antihypertensive kwenikweni, mankhwalawa amayenera kutengedwa moyo wonse, pakakhala zovuta komanso zotsutsana.

Hypercalcemia ndi indapamide imatha kukhala chifukwa cha hyperparathyroidism m'mbuyomu.

Odwala omwe ali ndi matenda a shuga, ndikofunikira kwambiri kuwongolera kuchuluka kwa shuga m'magazi, makamaka pamaso pa hypocapemia.

Kuchepa kwambiri kwa madzi kumatha kubweretsa kukula kwa impso kulephera (kutsekeka kwa kusefera kwa glomerular). Odwala amafunika kulipirira kuchepa kwa madzi ndikuwonetsetsa ntchito za aimpso poyambira chithandizo.

Indapamide ikhoza kupereka zotsatira zabwino mukamayendetsa doping control.

Odwala omwe ali ndi matenda oopsa komanso hyponatremia (chifukwa chodwala okodzetsa) ayenera kusiya kumwa mankhwala okodzetsa masiku 3 asanatenge ma Aitor inhibitors (ngati pangafunike, okodzetsa amatha kuyambiranso pambuyo pake), kapena akuwonetsedwera koyambirira kwa ma inhibitors a ACE.

Zida za sulfonamides zimachulukitsa nthawi ya systemic lupus erythematosus (iyenera kukumbukiridwa popanga indapamide).

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Munthawi ya chithandizo, chisamaliro chimayenera kuchitika poyendetsa magalimoto ndi kuchita zina zomwe zingakhale zoopsa zomwe zimafuna kuti anthu azisamalira komanso azithamanga kwambiri.

Kuyanjana kwa mankhwala

Saluretics, mtima glycosides, gluco- ndi mineralocorticoids, tetracosactide, amphotericin B (kudzera m'mitsempha), mankhwala othandizira zamadzimadzi amawonjezera ngozi ya hypokalemia.

Ndi munthawi yomweyo makonzedwe a mtima glycosides, mwayi wokhala ndi digitalis kuledzera ukuwonjezeka, ndi calcium kukonzekera - hypercalcemia, ndi metformin - ndikotheka kukulitsa lactic acidosis.

Imawonjezera ndende ya ma lithiamu ions m'madzi am'magazi (kuchepa kwa excretion mu mkodzo), lifiyamu imakhala ndi nephrotoxic.

Astemizole, erythromycin intramuscularly, pentamidine, sultopride, terfenadine, vincamine, gulu la 1a antiarrhythmic mankhwala (quinidine, disopyramide) ndi kalasi 3 (amiodarone, bretilium, sotalol) zitha kutsogolera kukula kwa arrhythmias a "torsades deors.

Mankhwala osokoneza bongo a nonsteroidal, glucocorticosteroid mankhwala, tetracosactide, sympathomimetics amachepetsa hypotensive zotsatira, baclofen imawonjezera.

Kuphatikiza kwa potaziyamu osagwiritsa ntchito mankhwala kungakhale kothandiza m'magulu ena a odwala, komabe, mwayi wokhala ndi hypo- kapena hyperkalemia, makamaka kwa odwala matenda a shuga komanso kulephera kwaimpso, sikuwatsimikiziridwa konse.

ACE inhibitors amachulukitsa mwayi wokhala ndi ochepa hypotension komanso / kapena aimpso kulephera (makamaka ndi aimpso a mtsempha wamagazi).

Zimawonjezera chiopsezo chokhala ndi vuto la impso mukamagwiritsa ntchito mankhwala oyerekeza ayodini omwe ali ndi vuto lalikulu. Musanagwiritse ntchito mankhwala okhala ndi ayodini, odwala ayenera kubwezeretsa kuchepa kwamadzi.

Imipramine (tricyclic) antidepressants ndi antipsychotic mankhwala amawonjezera hypotensive zotsatira ndikukulitsa chiopsezo cha orthostatic hypotension.

Cyclosporine imawonjezera mwayi wokhala ndi hypercreatininemia.

Imachepetsa mphamvu ya ma anticoagulants osalunjika (coumarin kapena indandion derivatives) chifukwa cha kuchuluka kwa zinthu zozizira chifukwa chakuchepa kwa kuchuluka kwa magazi ndi kuwonjezeka kwa kupanga kwawo kwa chiwindi (kusintha kwa mlingo kungafunike).

Imalimbitsa kutsitsa kwa kufalikira kwa mitsempha, kukulira pansi pa ntchito yopumitsa minofu yotsitsa.

Mndandanda wa mankhwala Indapamide

Zofanana muzochitika zamagulu:

• Acriptamide
• Acriptamide retard,
• Achter-Sanovel,
• Arindap,
• Arifon
• Arifon Penga,
• Vero-Indapamide,
• Indap,
• Indapamide MV Stad,
• Katundu wa Indapamide,
• Indapamide Stada,
• Indapamide-bind,
• Indapamide Werth,
• Indapamide teva,
• Zododometsa
• Indapsan
• Indipam
• India
• Ionik
• Jonik Retard
• Ipres Long
• Lorvas SR,
• Pamid
• Ravel SR,
• Kubwereza
• SR-Indamed,
• Makumi.

Indapamide ndi diazitrate wofanana ndi thiazide amenenso ali ndi katundu wa vasodilating. Ntchito kuchiza matenda oopsa.Thupi zowonjezera za Thiazide ndi thiazide akadali kutsogolo kwa mankhwala a antihypertensive. Mankhwalawa amagwiritsidwa ntchito ngati mankhwala oyamba onse kuthandizira komanso kuphatikiza mankhwala, ndipo kuphatikizidwa kwa mankhwala opatsirana polimbitsa thupi kumathandiza kwambiri kutsimikiza kwa mtima.

Makina a zochita za indapamide ali pafupi ndi a thiazides, zomwe sizodabwitsa, chifukwa onse magulu a mankhwala amachokera ku sulfonamides. Mankhwalawa amagwira ntchito yoyambira mbali za distal tubules, momwe zimakhalira nthawi zambiri, 5-10% ya sodium ndi chlorine ions yotsekedwa mu mkodzo woyamba umayambiridwanso, zomwe zikulepheretsa kuyamwa kumeneku. Ngakhale amakambirana pafupipafupi za zabwino ndi zovuta za thiazide ndi thiazide-okodzetsa poyerekeza wina ndi mzake, posachedwa, kutsogoza, ndikulimbikitsa kufalikira kwake ndi zotsatira za maphunziro ambiri azachipatala, ndizofanana ndi mankhwala ngati a thiazod. Mwachitsanzo, akatswiri a ku Britain kale amalimbikitsa ngati diuretics ya thiazide pochiza odwala omwe ali ndi matenda oopsa.

Chifukwa chazinthu zina zapadera, indapamide imachotsedwera ngakhale mkati mwa gulu lawo lamankhwala. Zinatsimikiziridwa motsimikiza kuti anali ndi vuto la vasodilating, lomwe limabweretsa gawo lake labwino pokwaniritsa zotsatira za antihypertensive. Ntchito ya vasodilating ya mankhwalawa imachitika chifukwa cha kuchuluka kwa mitsempha yamitsempha yamagazi kumayendedwe azinthu zingapo za vasopressor (norepinephrine, angiotensin II, thromboxane A2) ndi kuchepa kwa kuchuluka kwa ma radicals aulere, omwe amapezeka t.

kuphatikiza chifukwa cha kuletsa kwa peroxidation ya cholesterol "yoyipa". Indapamide ilinso ndi katundu wina wotsekemera wa calcium calcium. Chinthu china chosiyanitsa ndi mankhwalawa, chomwe chimasiyanitsa pakati pa thiazide ndi diuretics yofanana ndi thiazide, ndizodziwikiratu zomwe zimapangitsa kuti ntchito yake ikhale yotsutsa komanso yowonjezera mphamvu, zomwe zimatsimikiziridwa ndikuti zotsatira za antihypertensive kwa odwala omwe ali ndi matenda a impso akadali osasinthika. Lipophilicity (kuthekera kusungunuka m'mafuta) mu indapamil ndi dongosolo lalikulu kwambiri kuposa la thiazides ena, lomwe limapatsa mwayi wodziunjikira m'maselo osalala a minofu.

Kumapeto kwa zaka zana zapitazi, zofunikira zidapangidwa kuti zikhale zothandiza kwa antihypertensive mankhwala: nthawi yotsatila inali pafupifupi maola 24 (malinga ndi mlingo umodzi) komanso kufanana kwa antihypertensive kwenikweni, komwe kumalimbikitsidwa ndikusowa kwa kusinthika kwakukulu pakuchitika kwazinthu zodwala m'magazi. Kuti muthane ndi vutoli (pang'ono pokha) vutoli, mitundu ya inapamide yomwe imadziwika kuti yapezeka kale. Njira ya mayamwidwe ake mu chakudya cham'mimba ndikofunikira kuonetsetsa kuti mankhwalawo akufanana. Wothandizila antihypertgency sayenera kulowerera onse nthawi imodzi, chifukwa potere, kutsika kwakukulu kwa magazi kumachitika. Fomu la retard limapewa kutanthauzira kosiyanasiyana kwa kuchuluka kwa mankhwalawa m'magazi komanso kusakhazikika kwa pharmacological chifukwa pakapita nthawi. Indapamide mwanjira yotulutsira iyi imatha kupezeka m'mafakisi otchedwa "indapamide retard."

Mankhwala Stada Indapamide MV STADA - ndemanga

Chimodzi mwazomwe ndimamwa mankhwala omwe dokotala adandiyesera kuti andikayeze (ndipo makamaka pali ambiri aiwo) anali mankhwalawa. Ndazolowera kusinthana ndikuyamba kugwiritsa ntchito mankhwala osokoneza bongo kuyambira nthawi yopanga ma nootropics, ndikulole zopeka komanso mankhwala ena, pomwe nthawi zina pamakhala zotsatirapo zabwino kotero kuti ndibwino kungokhala ndi zaka zanu zokha popanda mankhwala.

Ndidasokonekera.

bokosi loyera-loyera popanda frills monga momwe ziyenera kukhalira ndi mankhwala oopsa.

Idapamide PRICE - ma ruble 150.

Njira yofunikira kwambiri yoganizira kuchuluka kwake kwa mankhwala achilendo komanso abwino.

Mapiritsiwo ndi oyera, ochepa, amatenga malo yaying'ono m'thumba.

Amabisala ndikukhala pansi pa foil, yomwe imasankhidwa mosavuta ndi chala. Ndimakumbukira mwangozi anzanga omwe amabisa fayilo ya msomali, koma palibe chomwe ankataya m'thumba lodzikongoletsera.

Ndi kumeza, monga lamulo, kunalibe zovuta; inunso mulibe nthawi yoti mumve kukoma kwake. Inemwini, ndili ndi izi monga choncho.

Zakudya za Indapamide: timakumbukira momveka bwino kuti mlingo ndi nthawi zimayikidwa kwa ife Pokhapokha ndi dokotala atakambirana, momwe mungayesere kupanikizika, yang'anani mayeso, fufuzani ndi mapiritsi omwe alipo kale m'moyo wanu, komanso mukumbukira zolowerera mu thupi, masiku ovuta komanso ntchito ..

ASATSITSE kanthu. Indapamide ndi okodzetsa kwambiri kuti athetse komanso kuchepa kwa magazi.

MALANGIZO

Pang'ono pang'ono pazotsatira zoyipa

matenda ofanana ndi chimfine, kupweteka pachifuwa, kupweteka kumbuyo, matenda, kuchepa kwa mphamvu, kutsika kwa libido, chifuwa, thukuta, kuchepa thupi, kugwedezeka kwamiyendo, kapamba, kuchuluka kwa zokhudza zonse lupus erythematosus.

ZOKUTHANDIZA KWA ANTHU NDIPO KUTSOGOLA.

Funso lowawa kwambiri linali mphamvu yodulira mafuta nditangopeza bokosi loyera-ili m'manja mwanga. Sindinkafuna kukonzekera misonkhano yonse ndikugwira ntchito kutengera mzanga wapamtima.

Zovuta pachabe, mankhwalawa ndi ofewa, osakhwima ndipo sanayambitsa zochitika zanga kapena zikhumbo zasesa zonse m'njira, kuthamangira kuchimbudzi.

Kupanikizika sikutsika nthawi yomweyo, palibe monga choncho. Palibe mphindi 15, mwinanso kupitilira. Ndinkamwa piritsi ndikudikirira. Ngakhale sindikudziwa, kodi pali wina amene angatengeke mwachangu?

Panali vuto pokhudzana ndi mitundu ina ya mankhwalawo ndipo adotolo adandichotsa china chake.

Chifukwa chake tsatirani izi ndikuwuzani, onetsani mndandanda wazonse zomwe mumamwa.

Zathanzi zonse komanso chilimwe chodabwitsa! Samalani misempha yanu ndipo musaiwale kuyesedwa kuti mupewe madokotala!

1. 
   Okorokov, A.N. matenda a ziwalo zamkati. Gawo 8. Kuzindikira matenda a mtima ndi mitsempha yamagazi / A.N. Hams. - M: Zolemba zamankhwala, 2015. - 432 c.
2. 
   Vogelson, L.I. Matenda a mtima ndi mitsempha yamagazi / L.I. Vogelson. - M: Kudalira "Zopindulitsa zamankhwala", 1975. - 384 p.
3. 
   Yakovleva, N.G. Matenda oopsa: Moyo wopanda mantha: Njira zamakono kwambiri, zothandiza kwambiri za matenda, chithandizo, prof / N.G. Yakovleva. - Moscow: IL, 2011 .-- 160 p.

Ndiloleni ndidziwitse - Ivan. Ndakhala ndikugwira ntchito ngati dotolo wabanja kwa zaka zoposa 8. Ndikudziganizira kuti ndine katswiri, ndikufuna kuphunzitsa alendo onse omwe amabwera pamalowa kuti athetse mavuto osiyanasiyana. Zambiri za tsambali zasonkhanitsidwa ndikufufuzidwa mosamala kuti zidziwitso zonse zofunikira zitheke. Musanagwiritse ntchito zomwe zikufotokozedwa pa webusaitiyi, kufunsana ndi akatswiri ndizofunikira nthawi zonse.

Indapamide yotsitsa kuthamanga

Mankhwala ndi a thiazide-ngati okodzetsa omwe amakhala nthawi yayitali, amatha kuchepetsa magazi. Indapamide imagwiritsidwa ntchito pochita matenda oopsa, pomwe kupanikizika kumayamba kupitirira 140/90 mm Hg. Art., Ndi kulephera kwa mtima kosatha, makamaka ngati wodwala watupa.

Mankhwala amamasulidwa monga mapiritsi ndi mapiritsi a 1.5 ndi 2.5 mg. Amapangidwa ku Russia, Yugoslavia, Canada, Macedonia, Israel, Ukraine, China ndi Germany. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa ndi Indapamide.

Indapamide ndi mankhwala osungira calcium, omwe ndi abwino kwa odwala matenda oopsa a mafupa. Itha kugwiritsidwa ntchito ndi anthu omwe ali ndi hemodialysis, odwala matenda ashuga, okhala ndi hyperlipidemia. Pazovuta, amafunikira kuti azilamulira kuchuluka kwa glucose, potaziyamu, zizindikiro zina zomwe adokotala akuuzidwa.

Indapamide ya matenda oopsa

Makapiritsi kapena mapiritsi a kukakamiza kwa matenda oopsa amayamba kuchita mphindi 30 mutatha kumwa. Zotsatira za hypotonic zimatha maola 23-24.

Kuchepa kwa kuthamanga kwa magazi kumachitika chifukwa cha zotsatira za hypotensive, diuretic ndi vasodilating - kuthamanga kwa magazi kumayamba kutsika chifukwa cha mphamvu ya chinthu chomwe chikugwira, kuchotsa madzi owonjezera mthupi ndi kuchuluka kwa mitsempha yamagazi mthupi lonse.

Indapamide ilinso ndi katundu wamtima - amateteza ma cell a myocardial.Pambuyo pa chithandizo, matenda oopsa amatha bwino mkhalidwe wamanzere wamtima wamanzere. Mankhwalawa amachepetsa kukana mu zotumphukira ndi zotumphukira za arterioles. Popeza kuthamanga kwamkodzo kumayambitsa kuchuluka kwa mkodzo, komwe kumatsitsidwa madzimadzi ambiri, kuli koyenera kumwa mankhwalawo ngati pali edematous syndrome.

Zotsatira zotsutsana ndi Indapamide

Odwala oopsa omwe ali ndi matenda amkodzo, endocrine, m'mimba ndi mtima dongosolo ayenera kuwonjezera kufunsa dokotala. Kwa ma pathologies ena, mankhwalawa ali ndi mawonekedwe ogwiritsira ntchito kapena amatsutsana kwathunthu.

Indapamide sayenera kugwiritsidwa ntchito mwa ana ochepera zaka 18, oyembekezera. Ngati mankhwalawa amadziwitsidwa kwa mayi panthawi ya mkaka wa m`mawere, ndiye kuti mankhwalawa mwana amasamutsidwa ku zakudya zosafunikira.

Kugwiritsa ntchito Indapamide kumatsutsana ngati zotsatirazi zikupezeka:

Musanagule mankhwalawa, ndikofunikira kuti muphunzire malangizo omwe wapangidwira (omwe ali mu phukusi la mankhwalawo), chifukwa akuwonetsa zonse zokhudza kapangidwe kake, mawonekedwe ogwiritsira ntchito, zotsutsana ndi zina.

Zotsatira zoyipa za indapamide

Kugwiritsa ntchito bwino mankhwalawa mu 97% ya milandu, mankhwalawa sasokoneza thupi. Mwa anthu omwe atsala 3%, Indapamide imayambitsa mavuto. Zotsatira zoyipa kwambiri ndikuphwanya muyeso wamadzi-electrolyte: kuchuluka kwa potaziyamu ndi / kapena sodium kumachepa. Izi zimadzetsa kusowa kwamadzi (kusowa kwamadzi) m'thupi. Osowa kwambiri, mankhwala amatha kuyambitsa arrhythmia, hemolytic anemia, sinusitis ndi pharyngitis.

Zotsatira zina za Indapamide:

• ziwengo (urticaria, anaphylaxis, edincke's edema, dermatosis, zidzolo),
• Matenda a Lyell
• Kuuma kwa mucosa wamlomo,
• Matenda a Stevens-Johnson
• kutsokomola
• kufooka
• chizungulire
• kusanza, kusanza,
• kupweteka kwa minofu
• migraine
• mantha
• kukanika kwa chiwindi
• kapamba
• kudzimbidwa
• orthostatic hypotension.

Nthawi zina indapamide imasintha kapangidwe ka magazi ndi mkodzo. Mu kusanthula kungawone kuchepa kwa potaziyamu, sodium, kuchuluka kwa calcium, shuga, creatinine ndi urea. Thrombocytopenia, leukopenia, kuchepa magazi, agranulocytosis kumachitika kawirikawiri.

Kodi ndingalowetse bwanji mankhwalawa

M'malo mwa Indapamide, Indap imaloledwa. Mankhwalawa ali ndi mawonekedwe omwewo, koma amapangidwa ndi wopanga wina ndipo atha kukhala ndi muyeso wosiyana wa zomwe zimagwira. Pakakhala kusiyana, dokotala wopezekapo amayenera kusintha mankhwalawa.

Dokotala adzakuthandizaninso kuti mupeze ma fanizo omwe ali ndi chinthu chofanana kapena chochita. Pofunsidwa payekha, dokotala adzakuwuzani kuti ndi mankhwala ati omwe mungagwiritse ntchito: Indapamide kapena Hypothiazide, Arifon Retard, Veroshpiron, Hydrochlorothiazide, Diuver, Acriptamide, Ionic, Retapres. Mwina kutumikiridwa kwa ma diuretics ena omwe cholinga chake ndi kuchepetsa magazi.

Pomaliza

Mankhwala Indapamide modekha amachepetsa kupanikizika tsiku lonse. Pogwiritsa ntchito nthawi zonse komanso molondola, kuthamanga kwa magazi kumachepa m'masiku 7 kuchokera poyambira kukhazikitsa. Koma chithandizo sichingasokonezeke pakadali pano, chifukwa mankhwalawa amafika pakapita miyezi iwiri ndi iwiri kapena itatu. Kuti mugwire bwino ntchito mankhwalawa, muyenera kutsatira malangizo azachipatala: kutsatira zakudya zamagazi, sinthani nthawi yopumula, mankhwala ena.

Indapamide ndi diuretic yomwe imathandizira kubwezeretsanso kubwinobwino. Mankhwala, limodzi ndi mkodzo, amachotsa sodium, amathandizira kugwira ntchito kwa njira zama calcium, amathandizira kuti zipupa za arterial zitheke. Zimatengera thiazide diuretics. Amagwiritsidwa ntchito pochiza matenda oopsa komanso ngati chida chomwe chingagwiritsenso ntchito edema yoyambitsidwa ndi mtima.

Pharmacological kanthu ndi pharmacokinetics

A diuretic ndi yogwira mankhwala ndi indapamide.

Chotsirizachi chikufanana ndi thiazide diuretic m'mapangidwe. Indapamide ndi mtundu wa sulfonylurea.

Chifukwa cha mawonekedwe a kapangidwe kake, mankhwalawa samakhudza kwambiri kuchuluka kwa pokodza.

Ndiye pambuyo pa zonse, ndimachiritso ati a indapamide? Machitidwe a yogwira ntchito amachepetsa katundu pamtima, amakulitsa ma arterioles, amachepetsa kuthamanga kwa magazi. Ndipo nthawi yomweyo sizimakhudza chakudya cham'mimba komanso lipid metabolism, ngakhale odwala omwe ali ndi matenda ashuga.

Ubwino wina wake ndikuchepetsa kwa zotumphukira za mtima. Kutha kuchepetsa kuchuluka ndi unyinji wamanzere wamitsempha wamanzere. Kutsitsa kwake kumamvekanso ngakhale ndi odwala omwe amafunikira hemodialysis.

Pharmacokinetics

The bioavailability wa mankhwalawa ndi 93%. M'magazi mu maora awiri ndi awiri mumabwera nthawi yambiri ya kuchuluka kwa zinthu. Indapamide imagawidwa bwino mthupi. Imatha kudutsanso mu chotchinga ndi kuyimilira mkaka wa m'mawere.

Mankhwalawa amamangidwa kumapuloteni a magazi ndi 71-79% - chizindikiro chachikulu. Njira ya metabolic imachitika m'chiwindi ndikupanga ma metabolites osagwira. Chidacho chimachotsedwa m'thupi ndi mkodzo - 70%, 30% yotsalayo - yokhala ndi ndowe.

Hafu ya moyo wa indapamide ndi maola 14-18. Sizikudziwika ngati nthawi ino yasintha ndi aimpso komanso kwa chiwindi.

Indapamide ndi m'magulu azachipatala:

• Mankhwala a Thiazide ndi thiazide diuretic,
• Mankhwala osokoneza bongo omwe amakhudza dongosolo la renin-angiotensin.

Kugwiritsa

Imwani osaposanso kapisozi kamodzi patsiku, imwani pakamwa: muyenera kumeza yonse, osafuna. Imwani madzi pang'ono.

Ndizotheka kuwonjezera mlingo pokhapokha mukaonana ndi dokotala. Muyenera kukhala okonzekera kuti mukhale ndi okodzetsa kwambiri, koma nthawi yomweyo, kuwonjezeka kwa hypotensive zotsatira sikuwonedwa.

Mapiritsi oponderezedwa a Indapamide: contraindication

1. Kuphwanya chiwindi.
2. Anuria
3. Thupi lawo siligwirizana.
4. Gout
5. Ana ochepera zaka 18 - palibe zoyesa mu m'badwo uno.
6. Mimba, nthawi yotsatsa. Pakubala kwa mwana, kugwiritsa ntchito mankhwalawa kulibe chifukwa. Indapamide imatha kubweretsa vuto lakusowa kwa fetal. Ngati mukuyamwitsa mwana ntchito ndikofunikira, ndiye kuti muyenera kuyamwa mwana mkaka wa mayi. Mankhwalawa amapatsira mwana kwa iye.
7. Kusokonezeka kwazungulira muubongo (posachedwa kapena pachimake).
8. Hypokalemia.
9. Gwiritsani ntchito ndi mankhwala omwe amakulitsa nthawi ya Q-T.

Asanapereke mankhwala, wodwalayo nthawi zambiri amapitilira mayeso amitundu yonse. Makamaka ngati mukukayikira kuti mankhwalawa angayambitse kusintha kwa mchere wamadzi. Ngati mankhwalawa adalembedwabe, ndiye kuti ndi koyenera kuti nthawi zina mumayesedwe kuti mupeze zomwe zili m'magazi opanda magazi a fibrinogen, sodium, potaziyamu ndi magnesium.

Zimafunikanso kuwunika pafupipafupi momwe mulili wa nayitrogeni, glucose, uric acid, pH. Dokotala amayenera kuyang'aniridwa ndi odwala omwe ali ndi vuto la mtima (matenda a mtima), matenda a mtima, matenda a mtima. Odwala omwe atchulidwa ali ndi kuthekera kwakukulu kuposa ena onse omwe metabolic alkalosis ndi hepatic encephalopathy angayambike.

Indapamide + mankhwala ena

• Mphamvu ya antihypertensive ya mankhwalawa imasokonezeka motsogozedwa ndi ma salicylates omwe amapezeka pamankhwala akuluakulu komanso osagwirizana ndi mankhwala omwe si a antiidal.
• Wodwala akakhala kuti alibe madzi, kugwiritsa ntchito indapamide kumapangitsa kuti aimpso alephere. Njira yothetsera vutoli ndi kubwezeretsanso madzi m'thupi.
• Kuphatikiza ndi mankhwala omwe ali ndi mchere wa lithiamu kumawonjezera kuchuluka kwa lifiyamu m'magazi chifukwa chakufupika kwa chinthu. Ngati kulumikizana kotereku sikungapeweke, wodwala ayenera kuyang'anira kuchuluka kwa lifiyamu m'magazi.
• Glucocorticosteroids ndi tetracosactides amalepheretsa zotsatira za hypotensive. Cholinga chake ndikuti madzi ndi sodium ion amasungidwa m'thupi.
• Zithandizo zozizira zochokera m'matumbo a m'mimba ndizo hypokalemia provocateurs. Ngati mankhwalawa amagwiritsidwa ntchito limodzi, muyenera kuwunika potaziyamu mu seramu yamagazi kuti mupeze nthawi yodziwika bwino ya hypokalemia.
• Hyperkalemia imayamba chifukwa cha kuphatikiza kwa diuretic ndi diuretics, momwe amasungidwira potaziyamu.
• Chiwopsezo chokhala ndi kulephera kwa impso ndi owopsa ochepa chimawonjezeka pogwiritsa ntchito ACE zoletsa.
• Cyclosporine yokhala ndi indapamide imaphatikizira kuwonjezeka kwa plasma creatinine.
• A radiopaque chinthu chimayambitsa impso.
• Mankhwala okhala ndi estrogeni amatha kusokoneza mphamvu ya hypotensive. Cholinga chake ndikuti madzi amasungidwa mthupi.
• Hypercalcemia ndiyotheka chifukwa chamafuta amchere amchere.
• Ma antidepressants a triceclic mndandanda amatsogolera kuwonjezeka kangapo kwa hypotensive zotsatira.

Malangizo a Madokotala

1. Ngati palibe zotsatira mkati mwa mwezi umodzi, mulimonse musachulukitse mlingo wa indapamide - zidzabweretsa zovuta. M'malo mwake, dongosolo la chithandizo liyenera kuwunikiridwa.
2. Mankhwalawa nthawi zambiri amawagwiritsa ntchito ngati mankhwala.
3. Indapamide ndi mankhwala ogwiritsira ntchito nthawi yayitali. Mphamvu yokhazikika imawonekera pakatha milungu iwiri. Kuchuluka kwake kumachitika pambuyo pa milungu 12. Kugwiritsidwa ntchito kamodzi kumachitika pambuyo pa ola limodzi kapena awiri.
4. Nthawi yabwino kumwa mankhwalawa m'mawa pamimba yopanda kanthu.

Zotsatira zoyipa zikachitika, madokotala amalankhula za njira ziwiri zomwe zingachitike. Choyamba ndi kusiya kugwiritsa ntchito mankhwalawa. Chachiwiri ndikuchepetsa mlingo. Njira yachiwiri siiganizira kwenikweni, chifukwa zovuta zoyipa za mankhwalawo ndizowopsa. Indapamide imayambitsa matenda a chiwindi, kusinthika kwa kapangidwe ka magazi, magazi.

Momwe mungasinthe?

Ngati mankhwala alibe mankhwala ofotokozedwawo, ndiye amatha kusinthidwa ndi ena ndi zofanana. Pankhaniyi, amatha kukhala ndi mawonekedwe osiyana: ma dragees, mapiritsi, makapisozi. Koma izi sizikuwakhudza mankhwala.

Analogs a indapamide - chimodzimodzi tanthauzo pokonzekera ndi chinthu china chogwira ntchito:

• Ionik
• Zosangalatsa
• Enzix,
• Arifon Penga,
• Indapen
• Indapamide perindopril.

Synonyms ya mankhwala indapamide - mankhwala omwe ali ndi yogwira chimodzimodzi mankhwala (INN):

Popanda kuonana ndi dokotala, komanso mothandizidwa ndi katswiri wazamankhwala, mutha kuyimitsa modziyimira pawokha indapamide ndi mankhwala ena ofanana. Koma analogues iyenera kugulidwa pokhapokha ngati dokotala akuvomereza!

Zindikirani osewera

Ngakhale mapiritsi a indapamide si mankhwala mwachindunji omwe angagwiritsidwe ntchito ngati doping kuti athandize masewera othamanga. Koma nthawi yomweyo, World Anti-Doping Agency inaletsa osewera kuti azigwiritsa ntchito zakudya zilizonse. Cholinga chake ndikuti amathandizira kubisala chenicheni chobera munthu wina. Ndipo chizindikiritso cha indapamide mthupi la othamanga pa mpikisano zingamupangitse kuti asayanjidwe.

Zotsatira zake

Muyenera kusamala mukamamwa mankhwala ngati mukuyendetsa galimoto kapena mukuchita nawo zina zomwe zingakhale zoopsa. Mankhwalawa amaletsedwa kupereka kwa iwo omwe amagwira ntchito mosalekeza, mumkhalidwe wowonjezera chidwi, kwa omwe kuthamanga kwake kuli kofunikira.

Ndemanga za Indapamide

1. Ubwino wa mankhwalawa: modekha, okodzetsa, komanso opanikizika.

Zoyipa: zoyipa zimatheka (koma izi ndizowonjezereka kuposa zoyipa).

Dmitry, wazaka 52. Dokotala wama neuropathologist adandiuza kuti ndithandizire izi. Ndimagwirizana ndi Losartan, chifukwa kuthamanga kwa magazi. Indapamide imakhala ndi zochulukirapo. Mutha kudzuka m'mawa, kuyezetsa zovuta, koma ndizabwinobwino, komabe muyenera kumwa mankhwalawo, apo ayi, zotsatira za mankhwalawo zimakulirakulira.

1. Sindimadwala kuponderezedwa pafupipafupi, nthawi zina pamakhala kulumpha.Chifukwa chake, ndimatenga mapiritsi a kupanikizika kwa indapamide osati tsiku ndi tsiku, koma pokhapokha ngati pakufunika. Ndikuwona zomwe anachita kwa maola angapo. Pambuyo pa kudumpha ndimamwa masiku 10 motsatizana kuti magazi azikhala bwino komanso osasunthika. Maphunziro oterowo akwanira kwa ine. Ndizotheka kuti muyenera kumamwa kamodzi patsiku, ndipo sizikukweza kwambiri maulendo opita kuchimbudzi.

Mankhwalawa amandiwopsa ndi kuchuluka kwa zoyipa, ndinawerenga pa intaneti ndikuganiza kale kuti sindigula. Koma adotolo adandiuza, ndipo ndinamvera. Ndekha, ndinapanga malingaliro angapo:

• Muyenera kumwa njira yonseyo, ngakhale zikuwoneka kuti kupsinjika ndi kale kale,
• Mankhwala amagwira ntchito mwachangu,
• Panalibe mavuto.

Madokotala amapereka mankhwala othandizira odwala matenda oopsa. Amathandizira kuchotsa madzi owonjezera mthupi.

Mankhwala wamba ndi Indapamide. Ndikofunika kuphunzira malangizo oti mugwiritse ntchito musanamwe mankhwalawa.

Kodi Indapamide imalembedwa liti?

Indapamide imapangidwira zochizira matenda oopsa. Mankhwalawa amalembedwa kuti azikhala ndi kuthamanga kwa magazi, komwe kumayambitsa kutupa ndikusungabe madzimadzi m'thupi.

Mukachotsa madzimadzi owonjezera, magazi amachepetsa (amachepetsa).

Mapiritsi a Pressure Indapamide ndiye gawo lalikulu pothandizira matenda oopsa. Kuphatikiza pa madokotala ake amupatsanso mankhwala ena omwe amapangira matenda oopsa.

Kodi Indapamide imathandizira bwanji? Mankhwalawa amalembera kuthamanga kwa magazi, komwe kumayambitsa kukula kwa matenda oopsa kwambiri. The harbinger wa ochepa matenda oopsa ndi 142/105.

Indapamide ndi diuretic, ntchito yayikulu ndikuchotsa madzi owonjezera mthupi. Mankhwala amatengedwa ngati diuretic.

Ngati mukumwa mankhwalawa mu Mlingo waukulu, sizipangitsa kuti mankhwala ena asinthe. Nthawi yomweyo, katundu wa diuretic amalimbikitsidwa. Chifukwa cha izi, madokotala samalimbikitsa kuti azichita okha mwanjira imeneyi.

Mtengo wa Indapamide ndi wapakati pa 25 mpaka 55 rubles.

Kodi simuyenera kutenga nthawi yanji?

Indapamide ndizoletsedwa kwa odwala omwe ali ndi:

• chiwindi ntchito,
• anuria (kutaya kwamkodzo kwathunthu mu chikhodzodzo),
• thupi lawo siligwirizana ndi yogwira mankhwala.
• matenda kagayidwe
• kufalikira kwamatumbo
• kuchuluka kwa mafuta a potaziyamu m'magazi,

Madokotala salimbikitsa kumwa mankhwalawa kwa amayi apakati komanso panthawi yoyamwitsa. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimakhudza chitukuko cha intrauterine ndipo zingayambitse kuperewera kwa fetal.

Ngati, malinga ndi umboni, mayiyo ayenera kumwa mankhwalawa panthawi yoyamwa

Sitikulimbikitsidwanso kumwa mankhwalawa kwa ana ochepera zaka 18.

Asanalembe Indapamide kwa wodwala, dokotala ayenera kumutumiza kukayezetsa zina. makamaka, izi zimagwira ntchito panthawi yomwe wodwalayo ali ndi vuto losintha madzi amchere.

Ngati dotolo amupatsirani mankhwala, wodwalayo amapereka magazi masabata awiri aliwonse kuti dokotala azitha kuyang'anira kuchuluka kwa sodium, potaziyamu ndi magnesium m'magazi a magazi. Mulingo wa zotsalira wa nayitrogeni, uric acid ndi glucose umayang'anidwanso nthawi zonse.

Mankhwala akaperekedwa kwa odwala omwe ali ndi vuto la mtima kulephera, matenda a mtima, matenda ena, wodwalayo amakhala m'manja mwake. Zikatero, wodwalayo amakhala pachiwopsezo chotenga matenda a metabolic alkalosis ndi hepatic encephalopathy.

Kodi njira yamankhwala imatenga nthawi yayitali bwanji?

Mankhwala a antihypertensive akaperekedwa kwa odwala omwe ali ndi matenda oopsa, njira ya mankhwalawa imakhala milungu ingapo.Masewera a magazi atakhazikika, mutha kusiya kumwa.

Dokotala wokha ndi amene angathane ndi vutoli. Pofuna kupewa kuchulukanso kwa magazi, wodwalayo ayenera kutsatira zakudya zoyenera komanso malangizo onse omwe madokotala amakupatsirani.

Kutalika kwa maphunzirowa kumatsimikiziridwa ndi adokotala. Kwa wodwala aliyense, chithandizo chake chimatha kukhala mosiyana. Zonsezi zimatengera umunthu wa thupi komanso kuchuluka kwa matenda oopsa.

Malangizo apadera

Ngati, kuwonjezera pa Indapamide, wodwalayo amatenga mankhwala kuti athane ndi vuto la mtima, mankhwala opatsirana, ndiye kamodzi pa sabata ziwiri zilizonse ndikofunikira kuyesedwa ndikuwunika zomwe zili potaziyamu ndi ioninine m'magazi. Dokotala amawongolera mwadongosolo kuchuluka kwa potaziyamu, magnesium ndi sodium m'madzi a m'magazi.

Moyang'aniridwa ndi dokotala odwala amapezeka ndi matenda a mtima, matenda a mtima, matenda a mtima, kuchepa kwa mtima, komanso odwala okalamba.

Pangozi ndi odwala omwe ali ndi malire a Q-T. Amatsimikiza pogwiritsa ntchito electrocardiogram. Nthawi imeneyi imatha kuwonjezeka pobadwa, ndipo imatha kupangika chifukwa cha matenda.

Nthawi yoyamba yomwe dokotala amakupangira kuwunika kwa potaziyamu ambiri m'magazi patatha masiku angapo atalandira chithandizo.

Pofuna kuti wodwala atulutse madzi owonjezera m'thupi ndi chisonyezo cha kuthamanga kwa magazi kuti chikhale ndi zikhalidwe zoyenera, Indapamide imatengedwa moyo wonse. Koma, ngati wodwalayo alibe zotsatira zoyipa.

Miyezi yambiri ya kashiamu yamagazi imayambitsidwa ndi hyperparathyroidism yomwe kale idadziwika. Odwala omwe amapezeka ndi matenda ashuga, madokotala amayang'anira kuchuluka kwa shuga.

Poyerekeza ndi kuchepa kwa madzi m'thupi, kulephera kwa impso kumayamba, kusefera kwamadzi kumachepa. Pachifukwa ichi, odwala amalipira chifukwa cha kuchepa kwamadzi m'thupi ndi mankhwala.

Kuti mukwaniritse izi, odwala amayamba kuwongolera. Odwala omwe ali ndi matenda oopsa, asanayambe chithandizo, ayenera kusiya kulandira mankhwala okodzetsa. Ngati simungathe kuchita popanda okodzetsa, ndiye kuti mutha kubwezeretsa kudya kwawo pambuyo pake. Zikatero, madokotala amatipatsa mankhwala ochepetsa mphamvu ya eniotensin osinthika kwambiri.

Mankhwalawa amachepetsa chidwi ndi zomwe akuchita, kotero simuyenera kuyendetsa galimoto ndikuchita zinthu zoopsa panthawi ya chithandizo.

Kuchita kwa indapamide ndi mankhwala osokoneza bongo

1. Kuphwanya kwa hypotensive zotsatira kumawonedwa pamene mukumwa mankhwala a Indapamide ndi ma salicylates komanso mankhwala ena osagwiritsa ntchito mankhwala oletsa kuponderezana.
2. Wodwala akakhala ndi vuto la kusowa madzi m'thupi, Indapamide imayambitsa matenda a impso. Zikatero, muyenera kubwezeretsanso madzi.
3. Miyezo ya lithiamu yamagazi imatha kuwonjezeka ngati mankhwala omwe ali ndi mchere wa lithiamu amatengedwa ndi Indapamide. Izi zimachitika chifukwa chakuchepa kwa zinthu zakunja. Ngati wodwala akufunika kumwa mankhwala ovuta, ndiye kuti muyenera kukayezetsa.
4. Mankhwala osokoneza bongo omwe ali ndi glucocorticosteroid ndi tetracosactide amatha kusokoneza hypotensive. Izi ndichifukwa chosungira ma sodium ndi ayoni amadzi mthupi.
5. Mankhwala okhala ndi mankhwala ofewetsa thukuta angayambitse hyperkalemia. Ngati dokotala amakufotokozerani mankhwalawa movutikira, ndiye kuti muyenera kuyang'anira kuchuluka kwa potaziyamu mu seramu yamagazi kupewa matenda.
6. Hyperkalemia imatha kukhazikika chifukwa cha kuphatikiza kwa okodzetsa ndi diuretic yomwe imasunga potaziyamu m'thupi.
7. Ngati Indapamide imagwiritsidwa ntchito limodzi ndi angiotensin-kutembenuza ma enzyme inhibitors, kulephera kwachulukidwe kaimpso ndi matenda osokoneza bongo angayambike.
8. Magazi a placma a creatinine amatha kuchuluka chifukwa cha kuphatikiza kwa indapamide ndi cyclosporine.
9. Kugwiritsa ntchito zinthu za radiopaque kumabweretsa kulephera kwa impso.

Kodi madokotala amalimbikitsa chiyani?

Ngati mukumva kuti kumwa mankhwalawa kwa mwezi umodzi sikupereka zotsatira zomwe mukufuna, ndiye kuti palibe chifukwa choti muwonjezere mlingo, apo ayi, zotsatira zoyipa zingachitike.

Lankhulani ndi dokotala, akupatseni mankhwala ena.

Indapamide imatengedwa limodzi ndi mankhwala, zotsatira zake zimatchulidwa.

Njira ya mankhwala ndi Indapamide imawerengedwa kuti ndi imodzi mwazitali. Mutha kuzindikira zotsatira zake patatha masiku 10-14, komanso zotsatira zake zazikulu - patatha miyezi itatu. Yogwira ntchito imayamba kugwira ntchito patatha maola angapo mutamwa mapiritsi.

Ngati kukumana ndi vuto kumachitika pakumwa, funsani dokotala. Pali njira ziwiri zochotsera izi:

1. Dokotala amaletsa mankhwalawa.
2. Mlingo umachepetsedwa.

Madokotala nthawi zambiri amagwiritsa ntchito njira yoyamba, chifukwa zoyipa zomwe zimachitika ku Indapamide ndizovuta.

Munkhaniyi, mutha kuwerengera malangizo ogwiritsira ntchito mankhwalawa Indapamide. Amapereka ndemanga kuchokera kwa alendo omwe amabwera patsamba lino - ogwiritsa ntchito mankhwalawa, komanso malingaliro a akatswiri azachipatala pakugwiritsa ntchito diuretic Indapamide machitidwe awo. Chopempha chachikulu ndikuti muwonjezere ndemanga zanu za mankhwalawa: mankhwalawo adathandizira kapena sanathandizire kuchotsa matendawa, ndizovuta ziti zomwe zimawoneka ndi zotsatirapo zake, zomwe mwina sizinalengezedwe ndi wopanga. Ma Analogs a Indapamide pamakhala ma analogues omwe amapezeka. Ntchito mankhwalawa matenda oopsa mu akulu, ana, komanso pa nthawi yoyembekezera. Zimatenga nthawi yayitali bwanji kumwa mankhwalawa.

Indapamide - antihypertensive agent, thiazide-ngati okodzetsa mwamphamvu komanso mphamvu yayitali, benzamide yotengeka. Imakhala ndi zolimbitsa modabwitsa komanso zosakanikirana, zomwe zimalumikizidwa ndi kuphatikizika kwa sodium, chlorine, maayoni a hydrogen, komanso gawo lochepera la potaziyamu mu proximal tubules ndi gawo lozungulira la distal tubule ya nephron. Zotsatira za vasodilating ndi kuchepa kwa zotumphukira zamitsempha zonse zimatsutsana ndi njira zotsatirazi: kuchepa kwa kukhazikikanso kwa khoma lamitsempha kupita ku norepinephrine ndi angiotensin 2, kuwonjezeka kwa kaphatikizidwe ka ma prostaglandins omwe ali ndi ntchito ya vasodilator, komanso kuletsa kwa kashiamu kulowa m'makoma osalala amitsempha yamagazi.

Imachepetsa kamvekedwe ka minofu yosalala ya mitsempha, kumachepetsa kuphatikizira kwamitsempha yamagazi. Zimathandizira kuchepetsa kumanzere kwamitsempha yam'mimba. Mu mankhwalawa achire, sizimakhudza metabolidi ya lipid ndi carbohydrate (kuphatikiza odwala omwe ali ndi matenda a shuga a mellitus).

Mphamvu ya antihypertensive imayamba kumapeto kwa sabata loyamba / loyamba la sabata lachiwiri ndikumagwiritsa ntchito mosalekeza ndipo limatha kwa maola 24 motsutsana ndi gawo limodzi la mankhwala.

Pharmacokinetics

Pambuyo pakukonzekera pakamwa, imatengedwa mwachangu komanso kwathunthu kuchokera kumimba, bioavailability ndi yayikulu (93%). Kudya pang'onopang'ono kumachepetsa mayamwidwe, koma sizikhudza kuchuluka kwa zinthu zotengeka. Ili ndi kuchuluka kwakukulu kogawa, kudutsa zolepheretsa za histoeticological (kuphatikizapo placental), kudutsa mkaka wa m'mawere. Wopangidwira m'chiwindi. 60-80% imachotsedwa ndi impso mu mawonekedwe a metabolites (pafupifupi 5% imachotsedwa osasinthika), kudzera m'matumbo - 20%. Odwala omwe ali ndi vuto la impso, ma pharmacokinetics sasintha. Sichikupanga.

Zizindikiro

Kutulutsa Mafomu

2.5 mg mapiritsi okhala ndi mafilimu.

Mapiritsi okhala ndi 2,5 mg Stad.

1.5 mg mapiritsi okhala ndi mapiritsi a Indapamide MV.

1.5 mg achigonjetse mapiritsi.

Makapisozi 2,5 mg Werth.

Malangizo ogwiritsira ntchito ndi mtundu wa mankhwala

Mapiritsi amatengedwa pakamwa popanda kutafuna.Mlingo wa tsiku ndi tsiku ndi piritsi limodzi (2,5 mg) patsiku (m'mawa). Ngati pambuyo pa masabata 4-8 a mankhwala othandizira ofunikirawa sakukwaniritsidwa, osavomerezeka kuti muwonjezere mlingo wa mankhwalawa (chiopsezo chowonjezereka cha zotsatira zoyipa popanda kupititsa patsogolo anti-hypertensive effect). M'malo mwake, tikulimbikitsidwa kuti mankhwala ena a antihypertensive omwe si okodzetsa aphatikizidwe mu regimen ya mankhwala.

Milandu yomwe chithandizo chiyenera kuyamba ndi mankhwala awiri, mlingo wa Indapamide umakhalabe pa 2,5 mg kamodzi patsiku m'mawa.

Mkati, osafuna kutafuna, mumamwa madzi amadzimadzi ambiri, mosasamala kanthu za kudya, makamaka m'mawa pa 1.5 mg (piritsi 1) patsiku.

Ngati pambuyo pa masabata 4-8 a mankhwala othandizira ofunikirawa sakukwaniritsidwa, osavomerezeka kuti muwonjezere mlingo wa mankhwalawa (chiopsezo cha zotsatira zoyipa chimawonjezeka popanda kukulitsa mphamvu ya antihypertensive). M'malo mwake, tikulimbikitsidwa kuti mankhwala ena a antihypertensive omwe si okodzetsa aphatikizidwe mu regimen ya mankhwala. Milandu yomwe chithandizo chiyenera kuyamba ndi mankhwala awiri, mlingo wa Indapamide retard umakhalabe wofanana ndi 1.5 mg kamodzi patsiku m'mawa.

Okalamba odwala, plasma ndende ya creatinine iyenera kulamulidwa poganizira zaka, kulemera kwa thupi ndi jenda, mankhwalawa amatha kugwiritsidwa ntchito mwa odwala okalamba omwe ali ndi vuto laimpso labwinobwino kapena pang'ono.

Zotsatira zoyipa

• kusanza, kusanza,
• kukomoka
• kamwa yowuma
• gastralgia,
• kutsegula m'mimba
• kudzimbidwa
• asthenia
• mantha
• mutu
• chizungulire
• kugona
• kusowa tulo
• kukhumudwa
• kutopa,
• kufooka wamba
• malaise
• kuphipha kwamisempha
• kusakhazikika
• conjunctivitis
• kuwonongeka kwamawonekedwe
• kutsokomola
• pharyngitis
• sinusitis
• rhinitis
• orthostatic hypotension,
• arrhasmia,
• kugunda kwa mtima
• nocturia
• polyuria
• zotupa
• urticaria
• kuyabwa
• hemorrhagic vasculitis,
• hyperglycemia, hypokalemia, hypochloremia, hyponatremia, hypercalcemia,
• chimfine ngati matenda
• kupweteka pachifuwa
• kupweteka kumbuyo
• utachepa potency
• yafupika libido
• Rhinorrhea
• thukuta
• kuwonda
• akumwetulira miyendo.

Contraindication

• anuria
• hypokalemia
• hepatic kwambiri (kuphatikizapo ndi encephalopathy) ndi / kapena kulephera kwaimpso,
• mimba
• kuyamwa
• zaka mpaka 18 - (kuchita bwino ndi chitetezo sizinakhazikitsidwe),
• kugwiritsa ntchito munthawi yomweyo mankhwala omwe amakulitsa nthawi ya QT,
• Hypersensitivity mankhwala ndi zina zotumphukira sulfonamide.

Mimba komanso kuyamwa

Contraindified mu mimba ndi mkaka wa m`mawere.

Malangizo apadera

Odwala omwe amatenga mtima glycosides, mankhwala ofewetsa thukuta, motsutsana ndi maziko a hyperaldosteronism, komanso okalamba, kuwunika pafupipafupi zomwe zili ndi potaziyamu ayoni ndi creatinine kumawonetsedwa.

Mukumwa mankhwala a indapamide, kuchuluka kwa potaziyamu, sodium, magnesium m'magazi am'magazi (kusokonezeka kwa elekitirogirisi kumatha kuchitika), pH, kuchuluka kwa glucose, uric acid ndi nitrogen yotsalira kuyenera kuyang'aniridwa mwadongosolo.

Kuwongolera kosamala kwambiri kumawonetsedwa kwa odwala omwe ali ndi vuto la cirrhosis (makamaka ndi edema kapena ascites - chiopsezo chokhala ndi metabolic alkalosis, chomwe chimawonjezera chiwonetsero cha hepatic encephalopathy), matenda a mtima, kuperewera kwa mtima, komanso okalamba. Gulu lomwe likuwopseza limaphatikizanso odwala omwe ali ndi nthawi yayitali ya QT pa electrocardiogram (wobadwa mwatsopano kapena kukulira motsutsana ndi maziko a njira iliyonse ya pathological).

Muyeso woyamba wa kuchuluka kwa potaziyamu m'magazi uyenera kuchitika sabata loyamba la chithandizo.

Ngati okodzetsa ndi antihypertensive kwenikweni, mankhwalawa amayenera kutengedwa moyo wonse, pakakhala zovuta komanso zotsutsana.

Hypercalcemia ndi indapamide imatha kukhala chifukwa cha hyperparathyroidism m'mbuyomu.

Odwala omwe ali ndi matenda a shuga, ndikofunikira kwambiri kuwongolera kuchuluka kwa shuga m'magazi, makamaka pamaso pa hypocapemia.

Kuchepa kwambiri kwa madzi kumatha kubweretsa kukula kwa impso kulephera (kutsekeka kwa kusefera kwa glomerular). Odwala amafunika kulipirira kuchepa kwa madzi ndikuwonetsetsa ntchito za aimpso poyambira chithandizo.

Indapamide ikhoza kupereka zotsatira zabwino mukamayendetsa doping control.

Odwala omwe ali ndi matenda oopsa oopsa komanso sponatremia (chifukwa chodwala okodzetsa) ayenera kusiya kumwa mankhwala okodzetsa masiku atatu asanafike ku ACE zoletsa (ngati zingafunike, okodzetsa amatha kuyambiranso pambuyo pake), kapena akuwonetsedwera koyambirira kwa ma inhibitors a ACE.

Zida za sulfonamides zimachulukitsa nthawi ya systemic lupus erythematosus (iyenera kukumbukiridwa popanga indapamide).

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Munthawi ya chithandizo, chisamaliro chimayenera kuchitika poyendetsa magalimoto ndi kuchita zina zomwe zingakhale zoopsa zomwe zimafuna kuti anthu azisamalira komanso azithamanga kwambiri.

Kuyanjana kwa mankhwala

Saluretics, mtima glycosides, gluco- ndi mineralocorticoids, tetracosactide, amphotericin B (kudzera m'mitsempha), mankhwala othandizira zamadzimadzi amawonjezera ngozi ya hypokalemia.

Ndi munthawi yomweyo makonzedwe a mtima glycosides, mwayi wokhala ndi digitalis kuledzera ukuwonjezeka, ndi calcium kukonzekera - hypercalcemia, ndi metformin - ndikotheka kukulitsa lactic acidosis.

Imawonjezera ndende ya ma lithiamu ions m'madzi am'magazi (kuchepa kwa excretion mu mkodzo), lifiyamu imakhala ndi nephrotoxic.

Astemizole, erythromycin intramuscularly, pentamidine, sultopride, terfenadine, vincamine, gulu la 1a antiarrhythmic mankhwala (quinidine, disopyramide) ndi kalasi 3 (amiodarone, bretilium, sotalol) zitha kutsogolera kukula kwa arrhythmias a "mitundu ya" torsades.

Mankhwala osokoneza bongo a nonsteroidal, glucocorticosteroid mankhwala, tetracosactide, sympathomimetics amachepetsa hypotensive zotsatira, baclofen imawonjezera.

Kuphatikiza kwa potaziyamu osagwiritsa ntchito mankhwala kungakhale kothandiza m'magulu ena a odwala, komabe, mwayi wokhala ndi hypo- kapena hyperkalemia, makamaka kwa odwala matenda a shuga komanso kulephera kwaimpso, sikuwatsimikiziridwa konse.

ACE inhibitors amachulukitsa mwayi wokhala ndi ochepa hypotension komanso / kapena aimpso kulephera (makamaka ndi aimpso a mtsempha wamagazi).

Zimawonjezera chiopsezo chokhala ndi vuto la impso mukamagwiritsa ntchito mankhwala oyerekeza ayodini omwe ali ndi vuto lalikulu. Musanagwiritse ntchito mankhwala okhala ndi ayodini, odwala ayenera kubwezeretsa kuchepa kwamadzi.

Imipramine (tricyclic) antidepressants ndi antipsychotic mankhwala amawonjezera hypotensive zotsatira ndikukulitsa chiopsezo cha orthostatic hypotension.

Cyclosporine imawonjezera mwayi wokhala ndi hypercreatininemia.

Imachepetsa mphamvu ya ma anticoagulants osalunjika (coumarin kapena indandion derivatives) chifukwa cha kuchuluka kwa zinthu zozizira chifukwa chakuchepa kwa kuchuluka kwa magazi ndi kuwonjezeka kwa kupanga kwawo kwa chiwindi (kusintha kwa mlingo kungafunike).

Imalimbitsa kutsitsa kwa kufalikira kwa mitsempha, kukulira pansi pa ntchito yopumitsa minofu yotsitsa.

Mndandanda wa mankhwala Indapamide

Zofanana muzochitika zamagulu:

• Acriptamide
• Acriptamide retard,
• Achter-Sanovel,
• Arindap,
• Arifon
• Arifon Penga,
• Vero-Indapamide,
• Indap,
• Indapamide MV Stad,
• Katundu wa Indapamide,
• Indapamide Stada,
• Indapamide-bind,
• Indapamide Werth,
• Indapamide teva,
• Zododometsa
• Indapsan
• Indipam
• India
• Ionik
• Jonik Retard
• Ipres Long
• Lorvas SR,
• Pamid
• Ravel SR,
• Kubwereza
• SR-Indamed,
• Makumi.

Popeza pali mankhwala a analogi wa yogwira mankhwala, mutha kutsatira maulalo omwe ali pansipa ndi matenda omwe amathandizira mankhwala ndikuwona mawonekedwe ofananizira achire.

Indapamide ndi mankhwala okodzetsa a gulu la thiazide, omwe ali ndi hypotensive, vasodilator ndi diuretic (diuretic).

Mankhwalawa amagwiritsidwa ntchito pochiza matenda oopsa, a thiazide-ngati ndi thiazide diuretics amagwiritsidwa ntchito kwambiri mu antihypertensive mankhwala. Amagwiritsidwa ntchito ngati mankhwala oyambira ku monotherapy, ndipo monga gawo la chithandizo chophatikiza, kugwiritsa ntchito kwawo kumathandizira kusintha kwakukulu mu mtima.

Patsambali mupezapo zambiri zokhudzana ndi Indapamide: Malangizo onse omwe mungagwiritsire ntchito mankhwalawa, mitengo ya mankhwala, mankhwala, ndemanga zathunthu komanso zosakwanira, komanso ndemanga za anthu omwe agwiritsa ntchito Indapamide kale. Mukufuna kusiya malingaliro anu? Chonde lembani ndemanga.

Kutulutsa mawonekedwe ndi kapangidwe kake

Amapezeka mu mawonekedwe a makapisozi ndi mapiritsi omwe ali ndi chophatikizira chachikulu - indapamide, zomwe zili mu:

• 1 kapisozi - 2,5 mg
• 1 piritsi yokhala ndi utoto wa 2,5 mg
• Piritsi limodzi lautali wa zochitika pachithunzichi - 1.5 mg.

Zomwe zimapangidwira mapiritsi a Indapamide, okhala ndi mafilimu, amaphatikiza lactose monohydrate, povidone K30, crospovidone, magnesium stearate, sodium lauryl sulfate, talc. Chigoba cha mapiritsiwa chimakhala ndi hypromellose, macrogol 6000, talc, titanium dioxide (E171).

Zothandiza zigawo zam'mapiritsi zotulutsidwa zotulutsidwa: hypromellose, lactose monohydrate, silicon dioxide, colloidal anhydrous, magnesium stearate. Filamu sheya: hypromellose, macrogol, talc, titanium dioxide, utoto tropeolin.

Patsamba lamaukonde, kukonzekera kwa Indapamide kumalandiridwa:

• Makapisozi - okhala ndi ma polima a 10, 20, 30, 40, 50, 50, 100 kapena zodzaza matumba a zidutswa 10 kapena 30,
• Mapiritsi - matuza a 10 zidutswa.

Mankhwala

Indapamide ndi m'gulu la mankhwala a thiazide diuretic ndipo ali ndi zotsatirapo zama cell:

1. Imachepetsa kukana mu arterioles,
2. Amachepetsa kuthamanga kwa magazi (hypotensive effect),
3. Imachepetsa kukhathamira kwamitsempha yonse,
4. Akutulutsa mitsempha yamagazi (ndi vasodilator)
5. Zimathandizira kuchepetsa kuchuluka kwa hypertrophy yam'manja yamitsempha yamtima,
6. Ili ndi moderate diuretic (diuretic).

Mphamvu ya antihypertensive ya Indapamide imayamba kutengedwa pakadontho (1.5 - 2,5 mg patsiku), zomwe sizimayambitsa kukokoloka. Chifukwa chake, mankhwalawa angagwiritsidwe ntchito kuchepetsa kuthamanga kwa magazi kwa nthawi yayitali. Mukamamwa mankhwala a Indapamide pamtokosi waukulu, zotsatira zake zimakhala zambiri, koma zotsatira zake zimatulutsidwa. Kumbukirani kuti kuchepa kwa kuthamanga kwa magazi kumatheka sabata yatha mutatha kumwa Indapamide, ndipo zotsatira zopitilira zimayamba pambuyo pa miyezi itatu yogwiritsidwa ntchito.

Indapamide siyimakhudzanso kagayidwe kazakudya ndi mafuta, chifukwa chake, amatha kugwiritsidwa ntchito ndi anthu omwe ali ndi matenda a shuga, cholesterol yayikulu, etc. Kuphatikiza apo, Indapamide bwino imachepetsa kukakamiza kwa anthu omwe ali ndi impso imodzi kapena hemodialysis.

Zotsatira zoyipa

Mukamatenga Indapamide, kukula kwa zotsatirapo zake ndizotheka:

1. Kuchulukitsa kwa systemic lupus erythematosus,
2. Chifuwa, sinusitis, pharyngitis, kawirikawiri - rhinitis,
3. Urticaria, kuyabwa, zidzolo, hemorrhagic vasculitis,
4. Orthostatic hypotension, palpitations, arrhythmia, hypokalemia,
5. Matenda a kwamikodzo pafupipafupi, polyuria, nocturia,
6. Kusanza, kusanza, kudzimbidwa, kutsekula m'mimba, pakamwa owuma, kupweteka kwam'mimba, nthawi zina kwa chiwindi, kwa eppreatopathy,
7. Kugona, chizungulire, kupweteka mutu, mantha, asthenia, kukhumudwa, kusowa tulo, vertigo, kawirikawiri - malaise, kufooka, kusokonezeka, kuphipha kwa minofu, nkhawa, kusakhazikika,
8. Glucosuria, hypercreatininemia, kuchuluka kwa plasma urea nayitrogeni, hypercalcemia, hyponatremia, hypochloremia, hypokalemia, hyperglycemia, hyperuricemia,
9. Osowa kwambiri - hemolytic anemia, m'mapapo aplasia, agranulocytosis, leukopenia, thrombocytopenia.

Kuyanjana kwa mankhwala

1. Cyclosporin imalimbikitsa kukula kwa hypercreatininemia.
2. Erythromycin imatha kubweretsa tachycardia yokhala ndi michere yamitsempha yama cell.
3. Kukonzekera kokhala ndi ayodini kungapangitse kuchepa kwamadzi mthupi.
4. Aluretics, mtima glycosides, mankhwala ofewetsa tuvi tomwe timawonjezera ngozi ya potaziyamu.
5. Mankhwala osagwiritsa ntchito mankhwala osokoneza bongo, glucocorticosteroids amachepetsa mphamvu ya hypotensive.
6. Ma antidepressants ndi ma antipsychotic amalimbikitsa hypotensive kwambiri, kuwonjezera mwayi wokhala ndi orthostatic hypotension.

Tidalemba ndemanga za anthu okhudzana ndi Indapamide:

1. Valya. Dotolo adayambitsa Indapamide zaka zingapo zapitazo kuphatikiza ndi mankhwala ena atatu, atafika kwa dotolo ndi madandaulo a kuthamanga kwa magazi komanso kupweteka kwa mutu. Pang'onopang'ono adayamba kugwiritsa ntchito kokha, ndimamwa piritsi tsiku lililonse m'mawa, ndikasiya kumwa tsiku lotsatira nkhope yanga imatupa, matumba amawoneka pansi pamaso panga. Ndidamva kuti kugwiritsidwa ntchito kwa nthawi yayitali kumatha kubweretsa kuyambitsidwa kwa magnesium ndi calcium kwa thupi, nthawi zina ngati chiphuphu ndimamwa Asparkam.
2. Lana. Zaka 53, panali vuto la matenda oopsa zaka 4 zapitazo, matenda oopsa 2 tbsp., Adotolo adatulutsa indapamide 2,5 mg, enalapril 5 mg, ndi bisoprolol, chifukwa tachycardia nthawi zambiri, ndimamwa mapiritsiwa pafupipafupi m'mawa. Poyamba Bisoprolol adamwa, kenako adayamba kumva kupweteka mumtima mkati mwa iwo, tsopano ndi indapamide komanso enalapril. Kupsinjika m'mawa ndi 130 mpaka 95, madzulo kumachepa, chifukwa cha mapiritsi amatha kukhala 105 mpaka 90, ndipo pamene ali 110 mpaka 85, koma mtundu wina wa kutopa ndi kufooka kumamveka. Nthawi yotsiriza imakhala kupweteka mumtima.
3. Tamara Agogo akewo adapezeka kuti ali ndi matenda oopsa ndipo pofuna kuthana ndi vuto lakelo, dotolo wothandizira adamupatsa Indapamide. Ndinagula mankhwala muchipatala ndipo ndimapatsa wodwalayo m'mawa ndikupereka madzi akumwa. Zotsatira zake, izi zinapangitsa kuti agogo ake azikhala bwino masiku 10, kupanikizika sikunalumphe, koma kunayamba kuchepa (poganizira zaka zake). Pazonse, mankhwalawa adathandizira. Analimbikitsa.

Malinga ndi ndemanga, Indapamide ndi mankhwala othandiza kwambiri. Madotolo komanso odwala omwe ali ndi matenda oopsa amanenanso kuti mankhwalawa amaloledwa bwino. Zotsatira zoyipa ndizosowa kwambiri ndipo zimakhala zowuma. Odwala ambiri omwe amapezeka kuti ali ndi matenda oopsa amathanso mapiritsi m'moyo wawo wonse.

Mapiritsi a Indapamide ali ndi mapangidwe ofananikira pazomwe zimagwira. Awa ndi mankhwala ochizira kuthamanga kwa magazi:

• Acriptamide
• Acriptamide retard,
• Arindap, Arifon,
• Arifon retard (ofanana French),
• Vero-Indapamide,
• Indapamide MV-Stad (ofanana aku Russia),
• Indapamide Retard (ofanana ndi Russia),
• Mapangidwe a Indapamide,
• Zododometsa
• Indapsan
• Indipam
• Ionik
• Ionic retard
• Ipres kutalika
• Lorvas SR,
• Ravel SR,
• Kubwereza
• SR-Indamed.

Musanagwiritse ntchito fanizo, funsani dokotala.

Zosungirako ndi moyo wa alumali

Indapamide iyenera kusungidwa m'malo owuma otetezedwa ndi kuwala, kuchokera kwa mwana pamtunda wa 25 digiri.

Moyo wa alumali ndi miyezi 36, nthawi imeneyi itatha, mankhwalawo ndi oletsedwa.

Indapamide ndi mankhwala otchuka pochiza matenda oopsa. Uku ndi kusokosera, mphamvu zolimba, kosatha pogwiritsa ntchito.

Iwo ali vasodilating tingati, amachepetsa kutulutsa kwawo kwathunthu. Chimodzi mwazinthu zofunikira za Indapamide ndikutha kwake kuchepetsa kuchepa kwamitsempha yamanzere yamanzere.

Mankhwalawa samakhudza chakudya cha wodwala, lipid metabolism (odwala matendawa ndi okhawo). Ponena za antihypertensive kwenikweni, kugwiritsa ntchito mankhwalawa pafupipafupi, kumadziwonekera pakumapeto kwa sabata loyamba / koyambira kwa sabata lachiwiri.

Tsiku lonse, izi zimasungidwa ndi piritsi limodzi. Odwala omwe ali ndi matenda oopsa nthawi zambiri amakhala ndi chidwi ndi funso - momwe angachitire ndi Indapamide kuti iwonetse zonse zabwino zake. Ndipo izi ndi zolondola, chifukwa kutsatira malangizo ndikofunikira mwachangu kuti munthu athanzire.

Mankhwala amapatsidwa piritsi limodzi patsiku. Kulemera kwake ndi 2.5 mg, mankhwalawa amayenera kumwa m'mawa. Nthawi yowongolera ndi masabata 4-8, munthawi imeneyi mawonekedwe achire akuyenera kuwonetseredwa.

Nthawi zina samayang'aniridwa, koma mlingo sayenera kuchuluka. Ndi kuwonjezeka kwa chizolowezi, pamakhala chiopsezo cha mavuto. Komabe, pali njira yanthawi zonse - madokotala adzalembera mankhwala ena a antihypertensive omwe si okodzetsa.

Pali nthawi zina pamene chithandizo chimayamba nthawi yomweyo ndimankhwala awiri. Mlingo wa Indapamide pankhaniyi ukadali wosasinthika - piritsi limodzi patsiku m'mawa.

Ndi matenda ashuga

Mankhwalawa nthawi zambiri amathandizidwa ndi odwala matenda ashuga pamene magazi awo akwera. Imwani mankhwalawa pamodzi ndi mapiritsi ena.

Ma diuretics ambiri amalimbikitsa shuga wamagazi, sizomwe zimachitika ndi Indapamide.

Zochitika ngati izi pomwa mankhwalawa ndizosowa. Koma wodwalayo amalangizidwa kuti azigwiritsa ntchito mita nthawi zambiri, kuyeza shuga. Indapamide imagwiritsidwa ntchito limodzi ndi mankhwala ena.

ACE inhibitors, angiotensin II receptor blockers ochepa magazi, muteteze impso ku zovuta. Odwala omwe ali ndi matenda ashuga amapatsidwa Indapamide ndi Perindopril, omwe ndi ACE inhibitors. Kuphatikizika kotere kumachepetsa kuthamanga kwa magazi, kumachepetsa chiopsezo cha zovuta zamtima.

Chifukwa cha machitidwe a mankhwala, kuchuluka kwa mapuloteni mumkodzo kumakhazikika; impso sizivutika ndi zovuta za shuga.

Mwa odwala, Noliprel, wokhala ndi indapamide ndi perindopril, ndiwofunikira kwambiri.

Cholinga chawo ndikuchepetsa kupanikizika ndi chithandizo chake pamlingo wa 135/90 mm RT. Art. Noliprel salola kuti ichitike, Amlodipine amawonjezeredwa ku regimen ya mankhwala.

Mimba komanso kuyamwa

Indapamide ndi okodzetsa. Pamene mayi woyembekezera ali ndi matenda oopsa kapena edema, funso limadzuka - kodi ndizotheka kumwa mankhwalawa?

Madokotala amayankha mosasamala - kutenga Indapamide panthawi yapakati sikunayesedwe chilichonse.

Mankhwalawa angayambitse kusayenda kwa magazi a fetal-placental, ndipo izi, zimayambitsa kukula kwa vuto la kuperewera kwa fetal.

Ngati pakati pa mkaka wa m`mawere mayi amakhala ndi matenda oopsa ndipo sangathe kuchita popanda mankhwala, madokotala amatha kukupatsani mankhwalawa. Pankhaniyi, kuyamwitsa nthawi yomweyo kumayimitsidwa kuti pasamamwe thupi la mwanayo.

Zotsatira zoyipa

Indapamide ndi mankhwala ofunikira. Kuwongolera kwake sikumayendera limodzi ndi mawonekedwe a zovuta, amalemba okha mwa 2,5% ya odwala. Nthawi zambiri izi ndikuphwanya kwa electrolyte metabolism.

Zina mwazotsatira zoyipa:

Kugwiritsira ntchito mankhwala (kawirikawiri) kumatha kuyesa mayeso a labotore, mwachitsanzo, kukulitsa kuchuluka kwa creatinine, urea, m'magazi.

Makanema okhudzana nawo

Momwe mungatengere Indapamide pa mavuto akulu:

Indapamide ndi mankhwala ogwiritsira ntchito nthawi yayitali, mayeso a labotale adzazindikira nthawi yolandila.

Momwe mungagonjetsere Hypertension kunyumba?

Kuti muchotse matenda oopsa komanso kuyeretsa ziwiya, muyenera.

Munthawi ya chithandizo chovuta kwambiri cha matenda oopsa, dokotala amayenera kupereka okodzetsa, popeza kuthamanga kwa magazi kumachepetsa mwachangu ndi kutulutsa kwamadzi m'thupi. Makampani opanga mankhwala apanga mankhwala ambiri okodzetsa. Nthawi zambiri, ngati pali edema, dokotala amalembera Indapamide kuti akapanikizike. Komabe, mankhwalawa ali ndi contraindication komanso mawonekedwe ogwiritsira ntchito, chifukwa chake amafunika kugwirizanitsa chithandizo ndi dokotala.