Syringe cholembera cha insulin humulin: ndi chiyani, mtengo ndi kuwunika

Mankhwala a antidiabetesic Humulin NPH amakhala ndi insulin-isophan, yomwe imakhala ndi nthawi yayitali. Amapangidwira kuti azigwiritsa ntchito mosalekeza kuti magazi azikhala ndi shuga m'magazi wamba.

Ipezeka ngati kuyimitsidwa kwa kayendetsedwe ka zigawenga mdziko la USA ndi Eli Lilly ndi Company. Ndipo kampani yaku France yaku Lilly France imatulutsa insulin Humulin NPH mwanjira yamakokotedwe okhala ndi cholembera.

Mankhwala ali ndi mawonekedwe a kuyimitsidwa kwamtambo kapena kwamtambo.

Mphamvu ya pharmacological ndi kuchepa kwa shuga m'magazi chifukwa chakuwonjezera kwa maselo ndi minyewa pogwiritsa ntchito Humulin NPH. Mu shuga mellitus, kupanga kwa pancreatic insulin timadzi kumachepetsedwa, komwe kumafunikira chithandizo chamankhwala cha mahomoni.

Mankhwala amalimbikitsa kugwiritsidwa ntchito kwa glucose ndi maselo omwe amafunikira zakudya. Insulin imalumikizana ndi ma receptor apadera pamaselo a cell, omwe amachititsa kuti pakhale njira zingapo zamankhwala amtundu uliwonse, zomwe zimaphatikizapo, makamaka, kupanga hexokinase, pyruvate kinase, glycogen synthetase.

Kutumiza kwa glucose kumisempha kuchokera m'magazi kumachuluka, komwe kumakhala kocheperako.

Mankhwala

Achire zotsatira akuyamba ola limodzi jekeseni.
Kutsitsa kwa shuga kumatenga pafupifupi maola 18.
Zotsatira zazikulu zimakhala pambuyo pa maola awiri mpaka maola 8 kuchokera pakukonzekera.

Kusintha kotereku kwakanthawi kwamankhwala kumadalira malo omwe amayimitsidwa ndi kuyendetsa galimoto kwa wodwalayo. Izi zimayenera kuganiziridwanso popereka dongosolo komanso kuchuluka kwa makonzedwe.

Popeza nthawi yayitali zotsatira zake, Humulin NPH imayikidwa pamodzi ndi insulin yochepa komanso ya ultrashort.

Kugawa ndi kutulutsa thupi:

Insulin Humulin NPH simalowa mu chotchinga cha hematoplacental ndipo samatuluka m'matumbo a mayi ndi mkaka.
Inactivine mu chiwindi ndi impso kudzera enzyme insulinase.
Kuthetsa mankhwalawa makamaka kudzera impso.

Zosafunikira zoyipa zimaphatikizapo:

hypoglycemia ndimavuto owopsa komanso osakwanira kupanga. Kuwonetsedwa ndi kusazindikira, komwe kumatha kusokonezedwa ndi chikomokere cha hyperglycemic,
mawonetseredwe amatsitsi omwe amapezeka pamalo a jakisoni (redness, kuyabwa, kutupa),
kutsutsika
kupuma movutikira
hypotension
urticaria
tachycardia
lipodystrophy - mankhwala a kwawo a subcutaneous mafuta.

Malamulo ogwiritsira ntchito

Mankhwalawa amayenera kuperekedwa pakhungu la phewa, m'chiuno, matako kapena khoma lamkati lamkati, ndipo nthawi zina jekeseni wam'mimba amatha.
Pambuyo pa jekeseni, simuyenera kukanikiza mwamphamvu ndikulimbira malo omwe akhudzidwa nawo.
Ndi zoletsedwa kugwiritsa ntchito mankhwalawa.
Mlingo umasankhidwa payekha ndi endocrinologist ndipo umatengera zotsatira za kuyezetsa magazi kwa shuga.

Yaikulu katundu wa mankhwala

Mankhwalawa amagwiritsidwa ntchito pamaso pa insulin-wodwala matenda a shuga komanso mtundu wachiwiri wa matenda ashuga mellitus.

Pali mitundu ingapo ya mankhwala Humulin.

Mankhwalawa amasiyanasiyana munthawi yogwirira ntchito thupi.

Mpaka pano, mitundu yotsatirayi ya mankhwalawa ikupezeka pamsika wamankhwala:

Insulin Humulin P (wowongolera) - ndi mankhwala osokoneza bongo.
Humulin NPH ndi mankhwala omwe amatha kuwonetsa pakatikati, omwe amayamba kuwonetsa ntchito ola limodzi pambuyo pa kuperekedwa, ndipo zotsatira zabwino zimatheka pambuyo maola asanu ndi limodzi mpaka asanu ndi atatu.
Insulin Humulin M3 ndi mankhwala omwe amatha nthawi yayitali. Amapezeka mu mawonekedwe a kuyimitsidwa kwamitundu iwiri, yomwe ili ndi insulin Humulin Regular ndi Humulin NPH.

Kuphatikiza kwakukulu kwa mankhwalawa ndikofunikira kukhazikitsa njira yogwiritsira ntchito shuga, komanso kuthamangitsa mapuloteni a anabolism.

Humulin Regulator imagwiritsidwanso ntchito pochiza matenda amishuga amitundu 2 pamaso pa zinthu izi:

ngati pa zovuta mankhwala pali mawonekedwe a kukana mankhwala ochepetsa shuga,
kukula kwa ketoacidosis,
ngati matenda afooka.
kusokonezeka kwa metabolic kumachitika
ngati kuli kofunikira kusamutsa wodwalayo kuti akhale nthawi yayitali ya insulin.

Humulin ya insulin ikhoza kuperekedwa m'njira ziwiri zazikulu:

Kuyimitsidwa kwa jekeseni pansi pa khungu.
Yankho la jakisoni.

Mpaka pano, pali chiwerengero chachikulu cha mankhwala omwe amatha kulowa m'malo mwa Humulin. Awa ndi mankhwala a analog omwe ali ndi kapangidwe kameneka yogwira ntchito - insulin. Zina mwa izi ndi monga:

Actrapid ndi Apidra,
Biosulin ndi Berlsulin,
Gensulin ndi isofan insulin,
Insulong ndi Insuman,
Lantus ndi Pensulin.

Nthawi zina, kugwiritsa ntchito protamine hagedorn ndikotheka. Sizoletsedwa kusankha nokha kapena mankhwalawo. Ndi dokotala yekhayo wokhawo yemwe angafotokozere wodwala mankhwala omwe ali ndi mulingo woyenera, poganizira kuopsa kwa matenda ndi zina zake.

Malangizo ogwiritsira ntchito insulin Humulin NPH ndi M3: mtengo wa mankhwalawa ndi kuwunikira

Humulin NPH ndi mitundu ina ya gulu lamankhwala awa ndi mankhwala omwe amagwiritsidwa ntchito pochiritsa anthu omwe ali ndi matenda ashuga.

Mankhwala ali ndi katundu wachilengedwe wochepetsa shuga, popeza amapangidwa pamaziko a insulin yaumunthu.

Cholinga chachikulu cha zinthu zopangidwa mwaluso ndi kuchepetsa kuchuluka kwa shuga m'magazi ndikulowetsa mu minofu ndikuyiphatikiza ndi zochita za ma cell.

Humulin ndi chiyani?

Masiku ano, mawu akuti Humulin amatha kuwoneka mu mayina a mankhwala angapo omwe adapangidwa kuti achepetse shuga ya magazi - Humulin NPH, MoH, pafupipafupi komanso Ultralent.

Kusiyana kwa njira zopangira mankhwalawa kumapereka mawonekedwe aliwonse ochepetsa shuga ndi zomwe ali nazo. Izi zimazindikiridwa popereka mankhwala kwa anthu odwala matenda ashuga.

Kuphatikiza pa insulini (gawo lalikulu, loyesedwa mu IU), mankhwala ali ndi zotuluka, monga madzi osabala, protamines, carbolic acid, metacresol, zinc oxide, sodium hydroxide, etc.

Horoni ya pancreatic imayikidwa m'makalata, mbale, ndi zolembera. Malangizo omwe aphatikizidwa amadziwitsa za zomwe amagwiritsidwa ntchito ngati mankhwala a anthu.

Musanagwiritse ntchito, makatoni ndi mbale siziyenera kugwedezeka mwamphamvu; zonse zofunikira kuti madzi apitirize kuyipukusa ndikuzipukutira pakati pa manja.

Choyenera kwambiri chogwiritsidwa ntchito ndi odwala matenda ashuga ndi cholembera.

Kugwiritsa ntchito mankhwala omwe atchulidwa kumathandizira kuti zitheke kupeza chithandizo chokwanira kwa odwala omwe ali ndi matenda ashuga, chifukwa amathandizira kuti pakhale kuperewera kwathunthu komanso kuperewera kwa mphamvu ya amkati amkati. Fotokozerani Himulin (mlingo, regimen) ayenera kukhala wa endocrinologist. M'tsogolo, ngati pakufunika kutero, dokotala yemwe akukonzekera akhoza kuwongolera njira yochizira.

Mu matenda a shuga a mtundu woyamba, insulin imayikidwa kwa munthu moyo wonse. Ndi zovuta za mtundu wa 2 shuga, zomwe zimayendera limodzi ndi matenda amtundu wa concomitant, mankhwalawa amapangidwa kuchokera ku maphunziro osiyanasiyana. Ndikofunika kukumbukira kuti ndi matenda omwe amafunikira kukhazikitsa mahomoni opanga thupi m'thupi, simungakane mankhwala a insulini, apo ayi mavuto akulu sangathe kupewedwa.

Mtengo wa mankhwalawa gulu lama pharmacological zimatengera nthawi yochitapo ndi mtundu wa ma CD.Mtengo wowerengeka m'mabotolo umayambira ku ma ruble 500., mtengo wake m'matotolo - kuchokera ku ma ruble 1000., M'mapensulo a syringe ndi osachepera 1500 rubles.

Kuti mudziwe kuchuluka kwake ndi kumwa mankhwalawa, muyenera kulumikizana ndi endocrinologist

Zonse zimatengera zosiyanasiyana

Mitundu ya ndalama ndi momwe thupi limakhudzira zikufotokozedwa pansipa.

Mankhwalawa amapangidwa pogwiritsa ntchito ukadaulo wama DNA ndipo amakhala ndi nthawi yayitali. Cholinga chachikulu cha mankhwalawa ndikukhazikitsa kagayidwe ka glucose.

Imathandizira kuti muchepetse kusweka kwa mapuloteni ndipo imakhudzanso minofu ya thupi. Humulin NPH imawonjezera ntchito ya ma enzyme omwe amalimbikitsa mapangidwe a glycogen mu minofu minofu.

Kuchulukitsa kuchuluka kwa mafuta acids, kumakhudza kuchuluka kwa glycerol, kumathandizira kupanga mapuloteni komanso kumalimbikitsa kumwa ma aminocarboxylic acid ndi maselo amisempha.

Ma Analogs omwe amachepetsa shuga la magazi ndi:

Actrafan NM.
Diafan ChSP.
Wofukiza N.
Protafan NM.
Humodar B.

Pambuyo jekeseni, yankho limayamba kugwira ntchito pambuyo pa ola limodzi, mphamvu zonse zimachitika mkati mwa maola 2-8, chinthucho chimakhalabe chogwira ntchito kwa maola 18-20. Nthawi yakukonzekera kwa mahomoni kutengera mlingo womwe wagwiritsidwa ntchito, tsamba la jakisoni, ndi zochita za anthu.

Humulin NPH akuwonetsedwa kuti agwiritse ntchito:

Matenda a shuga omwe ali ndi insulin.
Woyamba anapeza matenda a shuga.
Amayi oyembekezera omwe ali ndi matenda osokoneza bongo omwe amadalira insulin.

Malangizowo akuti mankhwalawa saikidwa kwa anthu omwe ali ndi vuto la hypoglycemia, lomwe limadziwika ndi kutsika kwa magazi m'munsi mwa 3.5 mmol / l, m'magazi otumphukira - 3,3 mmol / l, kwa odwala omwe ali ndi hypersensitivity kwa zigawo zina za mankhwala.
Zotsatira zoyipa zomwe zingachitike mutagwiritsa ntchito mankhwalawa nthawi zambiri zimawonetsedwa:

Hypoglycemia.
Kuwonongeka kwamafuta.
Zokhudza zonse komanso zam'deralo.

Ponena za mankhwala osokoneza bongo a mankhwalawa, palibe zizindikiro zenizeni zosokoneza bongo. Zizindikiro zazikuluzikulu zimadziwika ngati chiyambi cha hypoglycemia. Vutoli limaphatikizidwa ndi kupweteka kwamutu, tachycardia, thukuta lotupa komanso khungu. Popewa zovuta zotere, dokotala amasankha kuchuluka kwa wodwala aliyense payekhapayekha, poganizira kuchuluka kwa glycemia.

Ndi mankhwala osokoneza bongo ambiri, hypoglycemia ingachitike.

Humulin M3, monga mankhwala am'mbuyomu, adapangidwa nthawi yayitali. Imadziwika mu mawonekedwe a kuyimitsidwa kwamitundu iwiri, makatoni am'magalasi amakhala ndi insulin humulin pafupipafupi (30%) ndi humulin-nph (70%). Cholinga chachikulu cha Humulin Mz ndikuwongolera kagayidwe ka glucose.

Mankhwalawa amathandizira kupanga minofu, imatulutsa shuga ndi aminocarboxylic acid m'maselo a minofu ndi minyewa ina kupatula ubongo. Humulin M3 imathandizira mu minofu ya chiwindi kusanduliza glucose kukhala glycogen, imalepheretsa gluconeogeneis ndikusintha glucose owonjezereka kukhala subcutaneous ndi visceral mafuta.

Zotsatira za mankhwalawa ndi:

Protafan NM.
Farmasulin.
Actrapid Flekspen.
Lantus Optiset.

Pambuyo pakubaya, Humulin M3 imayamba kugwira ntchito pambuyo pa mphindi 30-60, mphamvu kwambiri imapezeka mkati mwa maola 2-12, nthawi ya insulini ndi maola 24. Zomwe zimakhudza kuchuluka kwa ntchito ya Humulin m3 zimagwirizanitsidwa ndi tsamba losankhidwa ndi jekeseni, ndi zochitika zolimbitsa thupi za munthu ndi chakudya chake.

Anthu omwe ali ndi matenda ashuga omwe amafunikira chithandizo cha insulin.
Amayi oyembekezera omwe ali ndi matenda ashuga.

Neutral insulini zothetsera zimaphatikizidwa pakupezeka hypoglycemia ndi hypersensitivity pazomwe zimapangidwira. Mankhwala a insulin ayenera kuchitika moyang'aniridwa ndi dokotala, omwe amachotsa kukula ndi kusokonezeka kwa hypoglycemia, komwe kumatha, chifukwa chabwino kwambiri, chomwe chimayambitsa kukhumudwa komanso kutaya chikumbumtima, choyipa kwambiri - kumayambiriro kwa imfa.

Pa mankhwala a insulini, odwala amatha kudwala matendawa, omwe nthawi zambiri amakhala akuwukidwa, kusungunuka, kapena kutupira khungu pakhungu. Khungu limakhala yofanana pakadutsa masiku 1-2, pamavuto ena pamafunika masabata angapo. Nthawi zina zizindikirozi ndi chizindikiro cha jakisoni wolakwika.

Kuchepa kwachilengedwe kumachitika pang'onopang'ono nthawi zambiri, koma mawonekedwe ake ndi akulu kwambiri kuposa omwe adachita kale, monga kuyabwa kofulumira, kupuma movutikira, kuthamanga kwa magazi, kuseka kwambiri komanso kuthamanga kwa mtima. Mu zochitika zapadera, ziwengo zimatha kusokoneza moyo wa munthu, vutolo limakonzedwa ndi chithandizo chadzidzidzi, kugwiritsidwa ntchito mwaumoyo ndi kulandira mankhwala.

Mankhwalawa amalembera anthu omwe akufuna insulin.

Humulin regula - kuchita mwachidule

Humulin P ndi mtundu wopangidwira wa DNA wokhala ndi nthawi yayifupi. Cholinga chachikulu ndikukhazikitsa kagayidwe ka glucose. Ntchito zonse zomwe zimaperekedwa kwa mankhwalawa ndizofanana ndi mfundo yodziwitsidwa ndi ma humulin ena.

Njira yothetsera vutoli ikuwonetsedwa kuti igwiritsidwe ntchito ndi anthu omwe ali ndi matenda osokoneza bongo a mtundu woyamba ndi wachiwiri, ndikulimbana ndi thupi pakumwa mankhwala a hypoglycemic ndi mankhwala ophatikiza.

Humulin regula wasankhidwa:

Ndi matenda ashuga ketoacidosis.
Ketoacidotic ndi hyperosmolar chikomokere.
Ngati matenda ashuga adawoneka panthawi yobala mwana (kutengera kulephera kwa zakudya).
Ndi njira yaposachedwa yochizira matenda a shuga.
Mukasinthira ku insulin yowonjezera.
Pamaso pa opareshoni, ndi zovuta za metabolic.

Humulin P imaphatikizidwa chifukwa cha hypersensitivity pamagulu a mankhwala ndipo amadziwika kuti ali ndi hypoglycemia. Dokotala payekhapayekha amalembera wodwalayo mlingo ndi mtundu wa jakisoni poganizira kuchuluka kwa shuga m'magazi asanadye komanso pambuyo pa maola 1-2 atatha. Kuphatikiza apo, pakadutsa mlingo, kuchuluka kwa shuga pamkodzo ndi njira yodziwika bwino ya matendawa amakhudzidwa.

Mankhwala omwe amawaganizira, mosiyana ndi omwe adapita nawo, amatha kuperekedwa kudzera mwa intramuscularly, subcutanely and intrarally. Njira yodziwika kwambiri yoyendetsera ndi yodutsa. Pazovuta zovuta za shuga ndi chikomokere, odwala jekeseni a IV ndi IM amakonda. Ndi monotherapy, mankhwalawa amatumizidwa katatu pa tsiku. Pofuna kupatula kupezeka kwa lipodystrophy, malo a jakisoni amasinthidwa nthawi iliyonse.

Humulin P, ngati pakufunika, imaphatikizidwa ndi mankhwala a mahomoni amtundu wa nthawi yayitali. Zofananira za mankhwala:

Actrapid NM.
Biosulin R.
Insuman Rapid GT.
Rosinsulin R.

Mankhwalawa amadziwitsidwa ndikusintha kwa insulin yayitali

Mtengo wa izi m'malo umayambira ku ma ruble 185, Rosinsulin amadziwika kuti ndi mankhwala okwera mtengo kwambiri, mtengo wake lero ndi oposa ruble 900. M'malo insulin ndi analogue ziyenera kuchitika ndi nawo madokotala. Analogue yotsika mtengo ya Humulin R ndi Actrapid, wotchuka kwambiri ndi NovoRapid Flekspen.

Humulinultralente wotalikirapo

Insulin Humulin ultralente ndi mankhwala ena omwe amawonetsedwa kuti agwiritsidwe ntchito kwa odwala omwe ali ndi matenda a shuga. Chogulitsidwachi chimakhudzidwa ndi DNA yomwe imapangidwanso ndipo ndi chinthu chomwe chimagwiritsidwa ntchito kwa nthawi yayitali.

Kuyimitsidwa kumayambitsidwa patatha maola atatu jakisoni itatha, mphamvu yotsika imatheka mkati mwa maola 18.

Malangizo ogwiritsira ntchito akuwonetsa kuti nthawi yayitali ya Humulinultralente ndi maola 24-28.

Dokotala amakhazikitsa mlingo wa mankhwala kwa wodwala aliyense payekhapayekha, poganizira momwe wodwalayo alili. Mankhwalawa amaperekedwa popanda kuwonjezeredwa, jakisoni amapangidwa pansi pa khungu kawiri pa tsiku. Humulin Ultralente akaphatikizidwa ndi mahomoni ena opanga, jakisoni amaperekedwa nthawi yomweyo.

Kufunika kwa insulini kumawonjezeka ngati munthu akudwala, akukumana ndi zovuta, amatenga pakati pakamwa, glucocorticoids kapena mahomoni a chithokomiro. Ndipo, mmalo mwake, amachepetsa ndimatenda a chiwindi ndi impso, pomwe mukutenga ma MA inhibitors ndi beta-blockers.

Mndandanda wa mankhwalawa: Humodar K25, Gensulin M30, Insuman Comb ndi Farmasulin.

Ganizirani zotsutsana ndi zoyipa.

Monga ma humulin onse, insulin ultralente imayesedwa chifukwa cha hypoglycemia yomwe ikupitilira komanso chiwopsezo champhamvu cha zigawo zina za chinthu.

Malinga ndi akatswiri, zotsatira zoyipa sizimadziwonetsera zokha kuti siziyenda bwino.

Zotheka pambuyo pobayikiridwa ndi jakisoni wa lipodystrophy, momwe kuchuluka kwa minofu ya adipose mu minofu ya subcutaneous kumachepa, komanso kukana insulin.

Nthawi zina, mankhwalawa amayambitsa sayanjana.

Analogue yotchuka ya humulin - Protaphane

Insulin Protafan NM imawonetsedwa kwa matenda osokoneza bongo a mtundu woyamba ndi wachiwiri, pakulimbana kwa sulfonylurea, zotumphukira zamagulu a matenda ashuga, mu nthawi ya opaleshoni ndi yotsatila, kwa amayi apakati.

Protafan imaperekedwa kwa wodwala aliyense payekhapayekha, poganizira zosowa za thupi lake. Malinga ndi malangizo, kufunika kwa mlingo wowonjezera wa mahomoni ndi 0.3 - 1 IU / kg / tsiku.

Kufunika kumawonjezereka kwa odwala omwe ali ndi insulin kukokana (kuwonongeka kwa kagayidwe kazakudya ka maselo kupita ku insulin), nthawi zambiri izi zimachitika ndi odwala nthawi yakutha komanso kwa anthu omwe ali ndi kunenepa kwambiri.

Kuwongolera mlingo wa mankhwalawa kutha kuchitika ndi adokotala ngati wodwalayo ali ndi matenda ofanana, makamaka ngati matenda ndi matenda. Mlingo umasinthidwa matenda a chiwindi, impso ndi matenda a chithokomiro.

Protafan NM imagwiritsidwa ntchito ngati jekeseni wofikira mu monotherapy komanso kuphatikiza ndi ma insulin afupipafupi kapena achangu.

Humulin insulin: ndemanga, mtengo, malangizo ogwiritsira ntchito

Mu 1 ml. Mankhwala a Humulin Humulin ali ndi 100 IU ya insulin. Zosakaniza ndi 30% insulin yosungunuka ndi 70% insulin isofan.

Monga momwe othandizira amagwiritsidwa ntchito:

metacresol
phenol
sodium hydrogen phosphate heptahydrate,
hydrochloric acid,
glycerol
zinc oxide
protamine sulfate,
sodium hydroxide
madzi.

Kutulutsa Fomu

Kukonzekera kwa insulin Humulin M3 insulini imapezeka mu mawonekedwe a kuyimitsidwa kwa ma subcutaneous makonzedwe mu 10 ml mabotolo, komanso 1.5 ndi 3 ml makatoni, oikidwa m'mabokosi a 5 zidutswa. Cartridges adapangidwa kuti azigwiritsa ntchito syringes ya Humapen ndi BD-pen.

Mankhwala ali ndi hypoglycemic.

Humulin M3 amatanthauza mankhwala obwerezabwereza a DNA, insulin ndi kuyimitsidwa kwa jekeseni kawiri ndi nthawi yayitali.

Pambuyo mankhwala, mankhwala kukonzekera kumachitika pambuyo 30-60 Mphindi. Kuchuluka kwake kumatenga maola awiri mpaka 12, kutalika kwa zotsatirazi ndi maola 18-24.

Ntchito za humulin insulin zimatha kusiyanasiyana malinga ndi malo omwe mankhwalawo amaperekera, kulondola kwa mlingo wosankhidwa, zochita za thupi, wodwala, zina ndi zina.

Zotsatira zazikulu za Humulin M3 zimagwirizana ndi kayendedwe ka kusintha kwa shuga. Insulin ilinso ndi anabolic. Pafupifupi minofu yonse (kupatula ubongo) ndi minofu, insulin imayendetsa kayendedwe ka glucose ndi amino acid, komanso imayambitsa kuthamanga kwa protein anabolism.

Insulin imathandizira kusintha glucose kukhala glycogen, komanso imathandizira kusintha shuga yambiri kukhala mafuta ndikuletsa gluconeogeneis.

Zizindikiro zamagwiritsidwe ntchito ndi zoyipa

Shuga mellitus, momwe insulin tikulimbikitsidwa.
Matenda a gestational (shuga ya amayi apakati).

Kukhazikika hypoglycemia.
Hypersensitivity.

Nthawi zambiri pa mankhwala akukonzekera insulin, kuphatikiza Humulin M3, kukula kwa hypoglycemia kumawonedwa. Ngati ili ndi mawonekedwe owopsa, imatha kudzutsa chikumbumtima cha hypoglycemic (kuponderezana ndi kusazindikira) ngakhale kupangitsa kuti wodwalayo afe.

Mwa odwala ena, thupi lawo siligwirizana, kuwoneka pakuluma pakhungu, kutupa ndi kufupika kwa malo a jakisoni. Nthawi zambiri, matendawa amadzidzidzikira okha patatha masiku kapena milungu yochepa atayamba chithandizo.

Nthawi zina izi sizimalumikizana ndi kugwiritsa ntchito mankhwalawo pawokha, koma ndi chifukwa cha mphamvu ya zinthu zakunja kapena jakisoni wolakwika.

Pali ziwonetsero zomwe sizigwirizana ndi zachilengedwe. Amachitika kawirikawiri, koma zowopsa. Ndi izi, izi zimachitika:

kuvutika kupuma
kuyamwa kofananira
kugunda kwa mtima
dontho mu kuthamanga kwa magazi
kupuma movutikira
thukuta kwambiri.

Milandu yoopsa kwambiri, chifuwa chimatha kusokoneza moyo wa wodwalayo ndipo imafunikira chithandizo chamankhwala chodzidzimutsa. Nthawi zina insulin m'malo kapena desensitization chofunika.

Mukamagwiritsa ntchito insulin ya nyama, kukana, hypersensitivity kwa mankhwala, kapena lipodystrophy imayamba. Mukamapereka insulin Humulin M3, kuthekera kwa zotulukazi ndi pafupifupi zero.

Makulidwe a insulin

Kuti mupeze jakisoni moyenera mankhwalawo, muyenera kuchita njira zina zoyambirira. Choyamba muyenera kudziwa malo omwe jakisoniyo, sambani manja anu ndikupukuta malowa ndi nsalu yothinidwa ndimowa.

Kenako muyenera kuchotsa kapu yoteteza ku singano ya syringe, kukonza khungu (kutambasula kapena kutsina), ikani singano ndikupanga jakisoni. Kenako singano iyenera kuchotsedwa ndipo masekondi angapo, osafunikira, kanikizani tsamba la jekeseni ndi chopukutira. Pambuyo pake, mothandizidwa ndi kapu yakunja yoteteza, muyenera kumasula singano, kuichotsa ndikubwezeranso chipewa pa syringe.

Simungagwiritse ntchito singano yemweyo ya syringe kawiri. Vial kapena cartridge imagwiritsidwa ntchito mpaka itapanda kanthu, ndiye kuti imatayidwa. Ma cholembera a syringe amapangidwira kuti azigwiritsa ntchito payekha.

Bongo

Humulin M3 NPH, monga mankhwala ena omwe ali mgulu lino la mankhwala, alibe tanthauzo lenileni la mankhwala osokoneza bongo, popeza kuchuluka kwa shuga mu seramu yamagazi kumadalira kayendetsedwe kazinthu pakati pa msinkhu wa glucose, insulin ndi njira zina za metabolic. Komabe, bongo wa insulin yambiri imatha kukhala ndi zotsatirapo zoyipa kwambiri.

Hypoglycemia imayamba chifukwa cha kusamvana pakati pa zomwe zili ndi insulin m'magazi a plasma ndi mtengo wamagetsi komanso kudya.

Zizindikiro zotsatirazi ndizodziwika za hypoglycemia:

ulesi
tachycardia
kusanza
thukuta kwambiri,
kukopa kwa pakhungu
kunjenjemera
mutu
chisokonezo.

Nthawi zina, mwachitsanzo, ndi mbiri yayitali ya matenda a shuga kapena kuyang'anitsitsa kwake, Zizindikiro za kutha kwa hypoglycemia zimatha kusintha. Hypoglycemia yofatsa imatha kupewedwa pakutenga shuga kapena shuga. Nthawi zina mungafunikire kusintha kuchuluka kwa insulini, kuunikanso zakudya kapena kusintha zolimbitsa thupi.

Hypoglycemia wolimbitsa thupi nthawi zambiri amathandizidwa ndi subcutaneous kapena mu mnofu makonzedwe a glucagon, akutsatira mwa kumeza chakudya. Woopsa milandu, pamaso pa matenda a mitsempha, kukomoka kapena chikomokere, kuwonjezera pa jakisoni wa glucagon, kugwirizira kwa glucose kuyenera kuperekedwa mwachangu.

M'tsogolomo, pofuna kupewa kubwereranso kwa hypoglycemia, wodwalayo ayenera kudya zakudya zopatsa thanzi. Mikhalidwe yayikulu kwambiri ya hypoglycemic imafuna kuchipatala mwadzidzidzi.

Zochita Zamankhwala NPH

Kugwiritsa ntchito kwa Humulin M3 kumatheka chifukwa chokhala ndi mankhwala amkamwa a hypoglycemic, ethanol, zotumphukira za asidi wa asidi, zotsekemera za monoamine oxidase, sulfonamides, ACE inhibitors, angiotensin II receptor blockers, osasankha beta-blockers.

Mankhwala a Glucocorticoid, mahomoni okula, pakamwa pobayira, danazole, mahomoni a chithokomiro, thiazide diuretics, beta2-sympathomimetics amatsogolera kuchepa kwa mphamvu ya hypoglycemic ya insulin.

Limbitsani kapena, mutafooketsa kudalira insulin yomwe imatha lancreotide ndi ma analogu ena a somatostatin.

Zizindikiro za hypoglycemia zimatsitsidwa ndikutenga clonidine, reserpine ndi beta-blockers.

Migwirizano yogulitsa, yosungirako

Humulin M3 NPH imapezeka pa pharmacy pokhapokha ngati mwalandira mankhwala.

Mankhwalawa amayenera kusungidwa pamtunda wa madigiri 2 mpaka 8, sangathe kuwundana ndikuwonetsa kuwala kwa dzuwa ndi kutentha.

Vial yotseguka ya NPH imatha kusungidwa pamawonekedwe a 15 mpaka 25 kwa masiku 28.

Kutengera ndi kutentha kofunikira, kukonzekera kwa NPH kumasungidwa zaka 3.

Malangizo apadera

Kuchotsera chithandizo mosavomerezeka kapena kuikidwa pakulakwika (komwe kumakhala kofunika kwambiri kwa odwala omwe amadalira insulin) kungayambitse kukula kwa matenda ashuga a ketoacidosis kapena hyperglycemia, omwe angawononge moyo wa wodwalayo.

Mwa anthu ena, mukamagwiritsa ntchito insulin yaumunthu, zizindikiro za hypoglycemia zomwe zikubwera zimatha kusiyana ndi zomwe zimadziwika ndi insulin ya nyama, kapena zimatha kuwonetsa pang'ono.

Wodwala ayenera kudziwa kuti ngati kuchuluka kwa shuga m'magazi ndikwabwinobwino (mwachitsanzo, ndi insulin Therapy), ndiye kuti zizindikiro zomwe zikusonyeza kuti hypoglycemia ikhoza kutha.

Mawonetsedwe awa amatha kufooka kapena kuwoneka mosiyanasiyana ngati munthu atenga mankhwala a beta-blockers kapena ali ndi matenda osokoneza bongo a nthawi yayitali, komanso pamaso pa matenda a shuga.

Ngati hyperglycemia, monga hypoglycemia, siinakonzedwenso munthawi yake, izi zitha kuchititsa kuti ataye chidwi, chikomokere, komanso ngakhale kufa kwa wodwalayo.

Kusintha kwa wodwala kupita ku insulin ina ya insulin kukonzekera kapena mitundu yawo iyenera kuchitika kokha moyang'aniridwa ndi dokotala. Kusintha kwa insulin kukhala mankhwala okhala ndi zochitika zina, njira yopangira (DNA recombinant, nyama), mitundu (nkhumba, analog) ingafune mwadzidzidzi kapena, m'malo mwake, kusintha kosavuta kwa Mlingo wokhazikitsidwa.

Ndi matenda a impso kapena chiwindi, kusakwanira kwa ntchito ya pituitary, vuto la adrenal ndi chithokomiro, kufunikira kwa insulini kumatha kuchepa, komanso kupsinjika kwamphamvu kwamalingaliro ndi zina zina, m'malo mwake, zimawonjezeka.

Wodwala nthawi zonse ayenera kukumbukira mwayi wokhala ndi hypoglycemia ndikuwunika bwino momwe thupi lake limayendetsa galimoto kapena kufunika kwa ntchito yoyipa.

Monodar (K15, K30, K50),
Novomix 30 Flexspen,
Ryzodeg Flextach,
Humalog Remix (25, 50).
Gensulin M (10, 20, 30, 40, 50),
Gensulin N,
Rinsulin NPH,
Farmasulin H 30/70,
Humodar B,
Vosulin 30/70,
Vosulin N,
Mikstard 30 NM
Protafan NM,
Humulin.

Mimba komanso kuyamwa

Ngati mayi woyembekezera ali ndi matenda ashuga, ndiye kuti ndikofunikira kwambiri kuti azilamulira glycemia. Pakadali pano, zofuna za insulin nthawi zambiri zimasintha nthawi zosiyanasiyana. Mu trimester yoyamba, imagwera, ndipo chachiwiri ndi chachitatu chikuwonjezeka, kotero kusintha kwa mankhwalawa kungakhale kofunikira.

Komanso, kusintha kwa muyezo, kudya ndi kuchita masewera olimbitsa thupi zingafunikire panthawi yochepa.

Ngati kukonzekera kwa insulin kumene kumakhala koyenera kwa wodwala matenda a shuga, ndiye kuti ndemanga za Humulin M3 nthawi zambiri zimakhala zabwino. Malinga ndi odwala, mankhwalawa ndi othandiza kwambiri ndipo mothandizidwa alibe zotsatira zoyipa.

Ndikofunika kukumbukira kuti ndizoletsedwa kupatsa insulin nokha, komanso kusintha kwina.

Botolo imodzi ya Humulin M3 yokhala ndi voliyumu ya 10 ml imayambira ku 500 mpaka 600 ma ruble, phukusi la ma cartridge atatu a 3 ml okhala ndi ma ruble a 1000-1200.

Kodi cholembera ndi chani?

Anapangidwa kale mu 1983, koma lero pali mitundu ingapo ya chipangizo chotere. Mwambiri, cholembera chilichonse ndi syringe ya humulin kapena cholembera cha biosulin ndichofanana ndi cholembera (kuchokera pamenepo dzinali) ndipo chili ndi mawonekedwe awa:

Bokosi - mlandu wofanana ndi bokosi lochokera pachitsime,
Nyumba yotseguka mbali imodzi ndi yolowera mbali inayo. Chingwe chomwe chimadzazidwa ndi insulin chimayikidwa m'timabowo, mbali inayo chimakhala ndi batani lotsekera, komanso limagwirira lomwe limatha kukhazikitsa mlingo wofanana ndi kuwonekera: kudina kamodzi - gawo limodzi.
Singano. Amayiyika kumapeto kwa malaya asanadzibaye jekeseni. Chingwecho chimapindika kuchokera pakatikati pa syringe, ndipo jakisoni utapangidwa, singano imachotsedwa.
Chipewa chomwe chimavalidwa pachidacho pomwe sichikugwiritsidwa ntchito. Cholembera cha syringe chimasiyana ndi cholembera cha insulin chifukwa chitha kugwiritsidwa ntchito nthawi zambiri mpaka zaka zingapo. Koma ndizosavuta kugwiritsa ntchito:

Mlanduwu umatseguka, chipangizocho chimachotsedwa, kapu imachotsedwa,
Singano imayikidwapo, chipewa chimachotsedwamo,
Cholembera chimagwira ndi dzanja kuti chisakanizikane ndi insulin m'manja. Mutha kujambulitsa kangapo,
Choyamba, mlingo wa mayunitsi awiri wakhazikitsidwa, batani la shutter limakanikizidwa. Kutulutsa mpweya wonse, ponyani dontho la insulin,
Tsopano mlingo wofunsidwa ndi wodwalayo wayikidwa, jakisoni amapangidwa (akhoza kukhala m'mimba, phewa, mkono kapena mwendo). Ngati ndi kotheka, jakisoni amapangidwa ngakhale kudzera mu zovala, chinthu chachikulu ndikupinda khungu,
Kanikizani batani la shutter ndikudikirira masekondi angapo. Sitimangolekerera mpaka kholingo yonse italowetsedwa,
Singano imatha kuchotsedwa, ikani chipewa pakompyutayo ndikubisa zonse zomwe zili.

Cholembera sichingakhale ndi zabwino komanso zovuta zake.

Chifukwa chake, njirayi ndi yabwino kwambiri: pambuyo pake, mutha kulowa insulin osasokoneza, ndipo kumalo ophunzirira kapena kuntchito, singano yake ndi yopyapyala kuposa ina iliyonse ndipo khungu silimavulala konse.

Oyenera anthu omwe ali ndi mavuto amaso komanso anthu olumala.

Mwa zoperewera ndikuti cholembera sichingathe kusweka nthawi zambiri, ndipo sizowoneka kuti chikukonzanso, chifukwa chipangizidwe chokhazikika cha kumwa chimaswedwa.

Kuphatikiza apo, chipangizochi sichotsika mtengo kwambiri, ndipo wodwala amafunikira ambiri aiwo, kuphatikiza imodzi yoti ilowe m'malo ndi iwiri ya ogwira ntchito. Izi ndi 150 kwa gawo lonse. Ma syringe ndiotsika mtengo. Inde, ndipo simungagule cholembera kulikonse.

Ndipo komabe, insulin m'mbale ndizofunikira kwambiri kuposa insulin ya zolembera. Kuphatikiza apo, ambiri opanga amapanga zolembera makamaka kuti apange insulin, chifukwa kuyitenga kumakhala kovuta.

Ndipo palinso cholembera cha jakisoni wa jekeseni wosachedwa wa mankhwala. Nthawi zambiri amagwiritsidwa ntchito ngati mankhwala mwadzidzidzi. Nthawi zina zolembera zotere zimaphatikizidwa mu zida zadzidzidzi. Zili bwino chifukwa ndi zosavuta kugwiritsa ntchito, ndipo mankhwala amangoperekedwa mosavuta. Zowonongeka zawo ndizodalirika pang'ono kuposa syringe yachizolowezi komanso mtengo waukulu.

Mitundu yotchuka ya ma syringes

M'malo mwake, pali ma syringe ambiri, pakati pawo, mwachitsanzo, pali ena omwe amangopanga ma insulini okha kuchokera kwa ena opanga, koma pali ena omwe amatchuka mu latency yathu.

Syringe cholembera biomatikpen. Wopangidwa ndi kampani yaku Swiss Ipsomed. Ali ndi pulogalamu yamagetsi kumapeto. Zowonetsera ndi kapangidwe kake ndizosavuta kusankha mtundu. Oyenera biosulin (P kapena H). Mlingo wapamwamba kwambiri ndi magawo 60. Mtengo - ma ruble 5,000,
Syringe cholembera autofoam yapamwamba. Okonzeka ndi ma adapter dispenser, komanso kuwonjezera kwa batani loyambira. Yogwirizana ndi singano iliyonse yotayika, yoyenera mitundu ya insulin monga biosulin, rosinsulin, gensulin ndi Eli Lilly.Chachikulu ndikuti voliyumu ya cartridge ikhale 3 mm. Palinso kusinthasintha kwa cholembera kotereku ndi kuwonjezereka kwa magawo awiri ndi muyeso waukulu wa magawo a 42.
Huma Pen Ergo. Sentensi yabwino ya humusulin yochokera kwa Eli Lilly. Masitepe ake ndiofanana gawo limodzi, lili ndi chotengera chotengera,
Syringe cholembera Novo pen 3. Chida chachitsulo kuchokera kwa opanga aku Danish Novo Nordisk. Ili ndi makina ounikira ndipo ndiyothandiza ma insulin monga Novomikst3, Protofan, Actrapid, Novorapid,
Opti Pen Pro 1. cholembera cha ku France chomwe chili ndi ma dispenser mwanjira yowonetsera pakompyuta. Chodabwitsa ndichakuti batri lawo silikwaniritsidwa, chifukwa chake limagwira zaka ziwiri zokha,
Novo Pen Echo. Syringe yamakono yochokera ku Dani yemweyo kuchokera ku Novo Nordisk. Zimasiyanasiyana pang'ono: 0. Zokwanira ma insulin okhala ndi U100 yamitundu iyi: Protofan, Novoparid, Actapride, komanso Novomikst3.

Wokhala ndi chiwonetsero chomwe chikuwonetsa mlingo wotsiriza wa insulin yomwe idabayira komanso pomwe idayilidwa. Mlingo wonse utalowetsedwa, chipangizocho chimapanga mawu akulu. Piston ili ndi stroke yosavuta, kotero ngakhale mwana amatha kugwiritsa ntchito chipangizo chotere ...

HumaPen Luxura HD. Chipangizo chinanso chopangira humulin. Ili ndi gawo laling'ono la theka la gawo, limapezeka mu mitundu yosiyanasiyana, ndipo chodabwitsa ndikuti pamene dokotalayo idayimbidwa, cholembera chimatuluka.

Syringe cholembera cha insulin Humulin: ndi chiyani, mtengo ndi ndemanga

Insulin Humulin NPH imagwiritsidwa ntchito pochiza odwala omwe ali ndi matenda a shuga 1. Odwala akuvutika chifukwa chakuti kapamba sangathe kudzipangira payekha insulin.

Humulin ndi cholowa m'malo mwa insulin ya anthu. Ndemanga zingapo zikuwonetsa mphamvu ya mankhwalawa komanso kulekerera kwake kosavuta.

Mtengo wa mankhwalawa umasiyanasiyana ma ruble 1,500. Masiku ano, mutha kupezanso mitundu yambiri ya mankhwala, komanso mankhwala ofanana.

Malangizo ogwiritsira ntchito mankhwalawa

Mlingo uliwonse wa mankhwalawa amadziwitsidwa ndi adokotala, potengera momwe wodwalayo alili ndi kuchuluka kwa shuga m'magazi.

Humulin Humulin Wowongolera akulimbikitsidwa kuti ajambulidwe pafupifupi theka la ola chakudya chachikulu chisanachitike, pomwe kuchuluka kwa jakisoni tsiku lililonse sikuyenera kupitirira sikisi.

Nthawi zina, jakisoni amapangidwa asanadye, koma pambuyo ola limodzi kapena awiri itatha.

Jakisoni watsopano aliyense amayenera kuyikidwa m'malo atsopano kuti apewe kupanga lipodystrophy. Regator yotere imatha kuthandizidwa mosagwirizana, kudzera m'mitsempha yamagazi ngakhale m'mitsempha. Njira zomalizazi zimakonda kuchitidwa ndi madokotala pochita opareshoni kapena odwala matenda a shuga.

Kuphatikiza apo, mankhwalawa nthawi zina amaphatikizidwa ndi mankhwala ena a antipyretic omwe amakhala nthawi yayitali.

Mlingo wofunikira wa mankhwala umatsimikiziridwa ndi katswiri wa zamankhwala, ndipo nthawi zambiri amakhala kuyambira magawo 30 mpaka 40 patsiku.

Ponena za mankhwala a Insulin Humulin NPH, ndizoletsedwa kugwiritsidwa ntchito mwa magazi. Kuyimitsidwa kapena emulsion imayendetsedwa pansi pa khungu kapena, nthawi zina, intramuscularly.

Kuti mupange jakisoni moyenera, mufunika maluso.

Algorithm yokhudza makulidwe a insulin Humulin NPH

Humulin mumbale mu mbale musanagwiritse ntchito uyenera kusakanizidwa ndikulowetsa vial pakati pa kanjedza mpaka khungu la mkaka litawonekera. Osagwedezeka, thovu, kapena kugwiritsa ntchito insulin yotsalira pamakoma a vial.
Humulin NPH m'makatiriji osati kungosuntha pakati pa manja, kubwereza kayendedwe ka 10, komanso kusakaniza, mofatsa kutembenuza bokosi. Onetsetsani kuti insulin ndi yoyenera kuyendetsedwa poyang'anira kusasinthasintha ndi mtundu. Payenera kukhala zofanana pamtundu wa mkaka. Komanso musagwedeze kapena kufumba mankhwala. Osagwiritsa ntchito yankho ndi phala kapena phala.Ma insulin ena sangayikiridwe katiriji ndipo sangathe kudzazidwanso.
Cholembera cha syringe chili ndi 3 ml ya insulin-isophan pa mlingo wa 100 IU / ml. Pa jakisoni 1, lowetsani osaposa 60 IU. Chipangizocho chimalola dosing ndi kulondola kwa 1 IU. Onetsetsani kuti singano ndiyomatirira pachidacho.

- Sambani m'manja pogwiritsa ntchito sopo, kenako muziwathandiza.

- Sankhani malo a jakisoni ndikuwachiritsa khungu ndi yankho la antiseptic.

- Masamba obayira enanso kuti malo omwewo sawagwiritsanso ntchito kamodzi pamwezi.

Momwe mungabayitsire mankhwalawa?

Pogwiritsa ntchito jakisoni wa insulin pansi pa khungu, muyenera kuwonetsetsa kuti singano sikulowa mumtsempha wamagazi, komanso musamayendetse kutikita minofu nthawi yomweyo jakisoni.

Masiku ano, pali zida zapadera za jakisoni, za insulin. Izi zimaphatikizapo makatiriji, cholembera, syringe ndi insulin.

Musanagwiritse ntchito kuyimitsidwa, iyenera kukhazikitsidwa m'manja kuti madzi mkati mwa ampoule akhale opanda ntchito. Nthawi yomweyo, churning, yomwe imathandizira kuti mawonekedwe a foam, iyenera kupewedwa.

Ngati syringe ya insulini imagwiritsidwa ntchito jekeseni, mlingo womwe adalimbikitsidwa ndi adotolo umakhazikitsidwa pamiyala ya 100 pa millilita imodzi. Ma cartridge apadera ali ndi malangizo awo oti mugwiritse ntchito, omwe muyenera kuti mudziwe bwino. Mmenemo, monga lamulo, pali chidziwitso cha momwe mungapangire bwino ulusi ndikukhomerera singano. Kuphatikiza apo, zida zotere zimapangidwa kuti zizigwiritsidwa ntchito kamodzi, kuzidzazanso ndizoletsedwa.

NPH ikhoza kugwiritsidwa ntchito molumikizana ndi Regator. Pankhaniyi, insulini yokhala ndi nthawi yochepa iyenera kuyamba kusonkhanitsidwa, kenako nkutalika. Pangani ngodya mosamala kuti mankhwalawa asasakanikirane.

Tiyeneranso kudziwa kuti magulu otsatirawa a mankhwalawa amatha kuchepetsa mphamvu ya mankhwala omwe amalowa m'magazi:

Kulera kwamlomo.
Corticosteroids.
Mankhwala a mahomoni pochiza matenda a chithokomiro.
Mitundu ina ya okodzetsa ndi antidepressants.

Kuonjezera kuchepetsa kutsika kwa shuga, monga:

mapiritsi a hypoglycemic,
acetylsalicylic acid
mowa ndi zokonzekera zomwe zili nazo.

Kuphatikiza apo, sulfonamides amatha kuwonjezera shuga kutsitsa.

Njira zopewera kugwiritsa ntchito mankhwalawa

Kusalolera kwa mankhwalawo komanso momwe zimakhudzira thupi zimaperekedwa pokhapokha ngati malangizo ndi madokotala onse omwe akupezekapo atsatiridwa mosamalitsa.

Pali nthawi zina pomwe zotsatira zoyipa zimatha.

Kupezeka kwa zoyambitsa kumachitika kawirikawiri kumakhudzana ndi kuphwanya njira ya jakisoni kapena kupitirira Mlingo woyenera.

Njira zopewera kusamala ndi izi:

Hypoglycemia imayamba, mawonekedwe owopsa omwe nthawi zambiri amayambitsa kuyambika kwa hypoglycemic coma. Wodwalayo angavutike mtima komanso kuti asamaganize bwino.
Kukula kwa thupi lawo siligwirizana, amene akuwoneka mu mawonekedwe a kuyabwa kwa khungu, redness, kutupa kwa zimakhala. Zizindikiro zoterezi ndizosakhalitsa, ndipo, monga lamulo, zimangokhala zokha pakapita masiku angapo.
Maonekedwe ngati zofunikira zonse. Kusintha koteroko kumayamba mu zovuta zomwe zimapangitsa kupuma, kutsekemera kwa mtima, komanso kutsika kwa kuthamanga kwa magazi pansipa zofunikira. Kupuma pang'ono komanso kutuluka thukuta kumawonekera.

Nthawi zambiri, lipodystrophy imatha kuonedwa. Malinga ndi ndemanga, kuwonetsa kolakwika kotere kungathe kukhala pokonzekera nyama.

Mankhwalawa ndiwotsutsana:

pamaso pa hypoglycemia, popeza imatha kutsitsa shuga,
ngati hypersensitivity imodzi kapena zingapo za mankhwala zimawonedwa.

Mlingo wosankhidwa kapena mankhwala osokoneza bongo amatha kudziwonetsa ngati ali ndi zizindikiro zotsatirazi:

Kutsika kwakukulu kwa shuga m'magazi kumakhala kovomerezeka.
Kuchuluka kwa mantha.
Mutu.
Kugwedezeka komanso kufooka kwathupi.
Maonekedwe a khunyu.
Kukongola kwa khungu.
Maonekedwe a thukuta lozizira.

Kuti muthane ndi zomwe zatchulidwazi, mutha kudya zakudya zomwe zimakhala ndi chakudya chamagulu ambiri. Ngati mankhwala osokoneza bongo ali ochulukirapo, muyenera kulumikizana ndi katswiri wazachipatala.

Mankhwalawa amatha kugwiritsidwa ntchito panthawi yoyembekezera kapena poyamwitsa. Tiyenera kudziwa kuti m'miyezi itatu yoyambirira kufunika kwa mahomoni mwa azimayi kumatsika, pambuyo pake (mu yachiwiri ndi yachitatu trimester) imachulukanso.

Kafukufuku wa zamankhwala awonetsa kuti kubaya insulini kulibe vuto la mutagenic.

Zomwe zimagwiritsidwa ntchito pa cholembera cha syringe

Chotsani kapu poikoka m'malo mozunguliza.
Onani insulin, moyo wa alumali, kapangidwe kake ndi mtundu wake.
Konzani singano ya syringe monga tafotokozera pamwambapa.
Pukuta singano mpaka itakhala yolimba.
Chotsani zisoti ziwiri ku singano.
Onani kuchuluka kwa insulin.
Pindani khungu ndikubaya singano pansi pakhungu pakona kwama degree 45.
Yambitsani insulini pogwira batani ndi chala chanu mpaka chitayima, kuwerengetsa pang'onopang'ono m'maganizo mpaka 5.
Mukachotsa singano, ikani nyemba za mowa pamalo a jekeseni osapaka kapena kupwanya khungu. Nthawi zambiri, dontho la insulin limatha kukhalabe kumapeto kwa singano, koma osati kutayikira, zomwe zikutanthauza kuti mlingo wosakwanira.
Tsekani singano ndi kapu yakunja ndikuitaya.

Kuyanjana kwina ndi mankhwala ena

Mankhwala omwe amalimbikitsa Humulin:

mapiritsi ochepetsa shuga,
antidepressants - monoamine oxidase inhibitors,
Hypotonic mankhwala ochokera pagulu la ACE zoletsa ndi beta blockers,
kaboni anhydrase zoletsa,
imidazoles
tetracycline mankhwala opha tizilombo,
Kukonzekera kwa lifiyamu
Mavitamini B,
theofylline
mankhwala okhala ndi zakumwa zoledzeretsa.

Mankhwala osokoneza bongo omwe amalepheretsa insulin Humulin NPH:

mapiritsi olembera
glucocorticosteroids,
mahomoni a chithokomiro
okodzetsa
mankhwala antidepressants,
othandizira omwe amachititsa kuti mitsempha ichite chisoni,
calcium blockers,
narcotic analgesics.

Zolemba za Humulin

Dzina la malonda	Wopanga
Insuman Bazal	Sanofi-Aventis Deutschland GmbH, (Germany)
Protafan	Novo Nordisk A / S, (Denmark)
Berlinsulin N Basal U-40 ndi Berlisulin N Basal chole	Berlin-Chemie AG, (Germany)
Actrafan HM	Novo Nordisk A / O, (Denmark)
Br-Insulmidi ChSP	Bryntsalov-A, (Russia)
Humodar B	Indar Insulin CJSC, (Ukraine)
Isofan Insulin World Cup	AI CN Galenika, (Yugoslavia)
Homofan	Pliva, (Croatia)
Biogulin NPH	Bioroba SA, (Brazil)

Ndemanga ya insulin-isophan antidiabetesic mankhwala:

Ndinkafuna kukonza - ndizoletsedwa kupereka insulin kwa nthawi yayitali!

Pharmacodynamics ndi pharmacokinetics

Humulin NPH ndi DNA imaphatikizanso insulin yaumunthu ndi nthawi yayitali yowonekera, zotsatira zake zazikulu ndikuwongolera shuga kagayidwe. Mankhwala amawonetsanso anabolic ogwira.

M'matupi a thupi la munthu (kupatula minyewa yaubongo), insulin Humulin NPH imayendetsa zoyendetsa ma amino acid ndi shuga, komanso imathandizira njira mapuloteni anabolism.

Kufanana mu chiwindi, mankhwalawa amalimbikitsa mapangidwe a glycogen kuchokera shugakumapangitsa kusintha kwa zochulukirapo shuga mu mafutazoletsa gluconeogenesis.

Kuyamba kwa insulin Humulin NPH kumawonedwa patatha mphindi 60 pambuyo paudindo, ndi mphamvu yokwanira munthawi ya 2 mpaka 8 mawola ndi nthawi ya ntchito mkati mwa maola 18-20.

Onani kusiyana komwe kumagwira ntchito insulin zimatengera kusankha kwa mlingo, malo a jakisoni, komanso zochitika zolimbitsa thupi za wodwalayo.

Zotsatira zoyipa

Zotsatira zazikulu zoyambira hypoglycemia, pomwe pamachitika zovuta kwambiri kumatha kuyambitsa kusazindikira komanso kufa (kawirikawiri).

Palinso kuthekera kochepa kakapangidwe lipodystrophy.

Thupi lawo siligwirizana ndi chikhalidwe:

Zomwe thupi lawo siliganiza:

kutupa kapena kuyabwa m'dera la jakisoni (nthawi zambiri amayima pakangotha milungu yochepa),
Hyperemia.

Malangizo ogwiritsira ntchito Humulin NPH

Mlingo wa Humulin NPH amasankhidwa payekha, molingana ndi mulingo wa glycemia wodwala.

Jakisoni wambiri wa Humulin NPH amaletsedwa!

Emulsion iyenera kuperekedwa, nthawi zina, jakisoni ya IM imaloledwa. Subcutaneous makonzedwe amachitika pamimba, phewa, matako kapena ntchafu. Malowo a jakisoni asinthidwe kuti kwa masiku 30 osaphatikizanso jakisoni imodzi.

Jakisoni wa SC amafunika luso lotsogolera komanso kusamala. Ndikofunikira kuti musalowe ndi singano m'mitsempha yamagazi, musamayesere malo a jakisoni, komanso kugwiritsa ntchito zida zoyendetsera mankhwalawa moyenera.

Kukonzekera ndi kutsata kwa Humulin NPH

Ndi cholinga insulin resuspension, musanagwiritse ntchito, Mbale ndi makatiriji a kukonzekera kwa Humulin NPH ndikulimbikitsidwa kuti ziguduzidwe kanthawi kokwanira m'manja khumi ndikugwedezeka kambiri nthawi imodzi (kutembenuka mpaka 180 °) mpaka kukonzekera kumapeza mawonekedwe osalala pafupi ndi mkaka kapena madzi amchere. Kugwedeza mankhwalawa mwamphamvu sikuyenera kutero, chifukwa chithovu chopangidwa mwanjira iyi chimatha kusokoneza kusankha kwenikweni kwa mlingo.

Mbale ndi ma cartridge ziyenera kuyang'aniridwa mosamala. Pewani kugwiritsa ntchito insulin ndi matope oyera kapena tinthu tating'ono tomwe timamamatira kukhoma kapena pansi pa botolo, ndikupanga mawonekedwe achisanu.

Kapangidwe ka cartridge sikuloleza zomwe zili mkati mwake kusakanikirana ndi zina insulin, komanso kudzazitsanso katoniyo.

Mukamagwiritsa ntchito Mbale, emulsion imasonkhanitsidwa pamenepo syringe insulin, yomwe voliyumu imafanana ndi potengera insulin (mwachitsanzo 100 IU / 1 ml insulin = 1 ml syringe) ndikuthandizira malinga ndi malingaliro a dokotala.

Mukamagwiritsa ntchito makatoni, ndikofunikira kutsatira malangizo a omwe amapanga cholembera kuti akhazikitse, kuphatikiza ndi singano, komanso kuyang'anira insulin, mwachitsanzo, malangizo a Humulin NPH mu cholembera cha Quick Pen.

Mukangobaya jekeseni, pogwiritsa ntchito kachipangiri kunja kwa singano, chotsani singanoyo ndikuiwononga m'njira yotetezeka, ndiye kutseka chogwirizira ndi kapu. Njirayi imaperekanso mphamvu yotseketsa, imalepheretsa mpweya kuti isalowe, imalepheretsa kutuluka kwa mankhwalawa ndi kutsekeka kotheka.

Masingano ndi zolembera sizingagwiritsenso ntchito kapena kugwiritsa ntchito ena. Mbale ndi ma cartridge amagwiritsidwa ntchito kamodzi mpaka mankhwala atamalizidwa, ndikuchotsedwa.

Mwina kuyambitsa kwa Humulin NPH kuphatikiza Humulin Wokhazikika.

Bwanji, pofuna kuti asalowe kulowa m'botolo insulin kuchitapo kanthu kwanthawi yayitali, woyamba kuyimba mu syringe insulin zochita zazifupi.

Kusakaniza uku ndikulimbikitsidwa kuti kuyambitsidwe mukangosakaniza. Kuti mupeze mlingo woyenera wa awiri insulin mutha kugwiritsa ntchito ma syringe osiyanasiyana.

Kuchita

Kuchita kwa Hypoglycemic kwa Humulin NPH kumachepa ndi kugwiritsidwa ntchito kofananira kulera kwamlomomahomoni a chithokomiro glucocorticoids, thiazide okodzetsatrousclic antidepressants, Diazoxide.

Kuphatikiza Ntchito Mowamankhwala a hypoglycemic (pamlomo), salicylatesMao zoletsa sulfonamides, opanga beta Sinthani zotsatira za hypoglycemic za Humulin NPH.

Reserpine, Clonidine ndi opanga beta amatha mafuta a hypoglycemia.

Mimba (ndi mkaka wa m'mawere)

Odwala ndi matenda ashuga dziwitsani wopereka chithandizo chazachipatala za kukonzekera kapena mwadzidzidzi mimba, mwachizolowezi, kufunikira kwa insulin amachepetsa mu trimester yoyamba ndikuwonjezeka mu trimesters yachiwiri ndi yachitatu (nthawi yofunikira kuikidwiratu insulin ndi kusintha kwina kwa mankhwala).

Komanso, zakudya komanso / kapena kusintha kwa mankhwalawa kungafunike panthawi yake nyere.

Mukamasankha insulin Dokotala amayenera kuwunika wodwalayo kuchokera kumbali zonse ndikusankha mankhwala omwe ali oyenera kwa wodwalayo.

Pankhaniyi, mankhwalawa Humulin NPH amawonetsa zotsatira zabwino zamankhwala ndipo angagwiritsidwe ntchito kwakanthawi.

Mtengo Humulin NPH, komwe mugule

Mutha kugula Humulin NPH pa avareji: botolo la 10 ml No. 1 - 550 ma ruble, 3 ml ma cartridge a No. 5 - 1500 rubles.

Humulin NPH kuyimitsidwa 100 IU / ml 10 ml Lilly Eli Lilly & Company
Humulin NPH kuyimitsidwa 100 IU / ml 3 ml 5 ma PC.

Humulin NPH kuyimitsidwa 100ME / ml 3ml No. 5 makatoni + QuickPenEli Lilly & cholembera makina
Humulin NPH kuyimitsidwa kwa 100ME / ml 3ml No. 5 makatiriji Eli Lilly & Company
Humulin NPH kuyimitsidwa 100MU / ml 10ml No. 1 botoloEli Lilly & Company

LAPANI ZOTSATIRA! Zambiri pamankhwala omwe ali pamalowo ndizokhudza zonse, zomwe zimatengedwa kuchokera kwa anthu ndipo sizingagwiritsidwe ntchito ngati lingaliro la kugwiritsa ntchito mankhwalawa munthawi ya chithandizo. Musanagwiritse ntchito mankhwala a Humulin NPH, onetsetsani kuti mwawonana ndi dokotala.

Gulani mu sitolo yathu cholembera cholembera HumaPen Luxura - DiaMarka

Syringe yabwino komanso yothandiza cholembera HumaPen Luxura ndi gawo la 1 unit. Cholembera cha syringe cha Eli Lilly (Eli Lilly) chili ndi katoni 3 ml. Chingwecho chili ndi mawonekedwe okongola, opindika.

Sitha kukhala njira yokhayo yolipirira shuga, komanso kukongoletsa kwenikweni ngati mungayike mthumba la malaya anu kapena jekete. Mlandu wolimba komanso wolimba umateteza cholembera kuti chisawonongeke, ngakhale mutaponya pansi mwangozi.

Kukula kwa mlingo ndi gawo limodzi.

Cholembera cha syringe chimapangidwa ndi Eli Lilly ndipo ndi choyenera kwa ma insulini onse a wopanga:

Yang'anani! Chophimba cha HumaPen Luxura Syringe cholembanso ndi insulin. Mtengo wa cholembera ichi cha Biosulin ndiwomveka.

Komanso, pachiwopsezo chanu komanso pachiwopsezo chanu, mutha kugwiritsa ntchito cholembera ichi pa insulin "pa Apidra.
Maukadaulo apadera Sringe zolembera HumaPen Luxura

Kapangidwe ka ma penfoles a 3 ml (mayunitsi 300).
Gawo lochepetsetsa ndi gawo la insulin ya 1 unit.
Mlingo wapamwamba mu seti imodzi ndi 60 magawo.
Miyeso: 165x25x23 mm
Kulemera: 30g.

Zambiri za cholembera HumaPen Luxura:

Kuwonekera ndi kuwongolera mawu polemba gawo lililonse la insulin
Kutha kuletsa mlingo
Makhalidwe abwino kwambiri "pamsonkhanowu
Maonekedwe okongola komanso osangalatsa
Chovuta cholimba, chapamwamba kwambiri chomwe chimakwaniritsa chogwiramo pachokha.

Humapen Luxura Syringe chole
Mlanduwu (pali malo owerengera singano zapamwamba ndi katemera wa insulin)
Malangizo mu Russian

HumaPen Luxura Syringe cholembera Chotsimikizika chogulitsa ku Russia. Zithunzi zamalonda, kuphatikiza utoto, zimatha kukhala zosiyana ndi mawonekedwe enieni. Zomwe zili pamaphukusi zimasinthanso popanda kuzindikira. Kulongosola uku sikuchokera pagulu.

HumaPen Luxura Syringe cholembera - mtengo 2150.00 rub., Chithunzi, maluso aukadaulo, momwe zinthu zilili ku Russia. Kugula HumaPen Luxura Syringe cholembera mu malo ogulitsira pa intaneti https: diamarka.com, lembani fomu yodula pa intaneti kapena kuyimba: +7 (3452) 542-147, +7 (922) 483-55-85.

Humulin: malangizo ogwiritsira ntchito, mtengo, ndemanga ndi analogi

Kukonzekera bwino kwa insulini kuyenera kukhala ndi zotsutsana pang'ono komanso zoyipa, chifukwa anthu odwala matenda ashuga ayenera kulimbana ndi matenda ena ambiri. Ndipo mankhwalawa amasiyana ndi ma analogu m'njira zingapo, kuphatikiza pazomwe ali. Onani chifukwa chake Humulin NPH ndi wabwino kwambiri kwa matenda ashuga mogwirizana ndi malangizo omwe angagwiritsidwe ntchito.

Opanga INN

Dzinalo lapadziko lonse lapansi ndi insulin-isophan (umisiri wa chibadwa cha anthu).

Imapangidwa makamaka ndi Lilly France SAAS, France.

Zoyimira ku Russia: "Eli Lilly Vostok S.A."

"Humulin" imasiyana pamtengo malinga ndi mtundu wa kumasulidwa: mabotolo kuchokera ku ma ruble 300-500, makatoni kuchokera ku ruble 800-1000. Mtengo ungasiyane m'mizinda yosiyanasiyana.

Zotsatira za pharmacological

Pharmacodynamics ndi pharmacokinetics

Humulin NPH ndi DNA imaphatikizanso insulin yaumunthu ndi nthawi yayitali yowonekera, zotsatira zake zazikulu ndikuwongolera shuga kagayidwe. Mankhwala amawonetsanso anabolic ogwira.

M'matupi a thupi la munthu (kupatula minyewa yaubongo), insulin Humulin NPH imayendetsa zoyendetsa ma amino acid ndi shuga, komanso imathandizira njira mapuloteni anabolism.

Kufanana mu chiwindi, mankhwalawa amalimbikitsa mapangidwe a glycogen kuchokera shugakumapangitsa kusintha kwa zochulukirapo shuga mu mafutazoletsa gluconeogenesis.

Kuyamba kwa insulin Humulin NPH kumawonedwa patatha mphindi 60 pambuyo paudindo, ndi mphamvu yokwanira munthawi ya 2 mpaka 8 mawola ndi nthawi ya ntchito mkati mwa maola 18-20.

Onani kusiyana komwe kumagwira ntchito insulin zimatengera kusankha kwa mlingo, malo a jakisoni, komanso zochitika zolimbitsa thupi za wodwalayo.

Zizindikiro zogwiritsidwa ntchito

Mankhwala Humulin NPH akuwonetsedwa kuti azigwiritsidwa ntchito ndi:

woyamba adapezeka matenda ashuga,
matenda ashugam'malo mwazizindikiro zakusankhidwa mankhwala a insulin,
mimba kumbuyo osachiritsika omwe amadalira shuga (mtundu 2).

Contraindication

hypoglycemiazomwe zikuwoneka pano
Hypersensitivity pa zosakaniza za Humulin NPH.

Zotsatira zoyipa

Zotsatira zazikulu zoyambira hypoglycemia, pomwe pamachitika zovuta kwambiri kumatha kuyambitsa kusazindikira komanso kufa (kawirikawiri).

Palinso kuthekera kochepa kakapangidwe lipodystrophy.

Thupi lawo siligwirizana ndi chikhalidwe:

Zomwe thupi lawo siliganiza:

kutupa kapena kuyabwa m'dera la jakisoni (nthawi zambiri amayima pakangotha milungu yochepa),
Hyperemia.

Malangizo ogwiritsira ntchito Humulin NPH

Mlingo wa Humulin NPH amasankhidwa payekha, molingana ndi mulingo wa glycemia wodwala.

Jakisoni wambiri wa Humulin NPH amaletsedwa!

Kukonzekera ndi kutsata kwa Humulin NPH

Ndi cholinga insulin resuspension, musanagwiritse ntchito, Mbale ndi makatiriji a kukonzekera kwa Humulin NPH ndikulimbikitsidwa kuti ziguduzidwe kanthawi kokwanira m'manja khumi ndikugwedezeka kambiri nthawi imodzi (kutembenuka mpaka 180 °) mpaka kukonzekera kumapeza mawonekedwe osalala pafupi ndi mkaka kapena madzi amchere. Kugwedeza mankhwalawa mwamphamvu sikuyenera kutero, chifukwa chithovu chopangidwa mwanjira iyi chimatha kusokoneza kusankha kwenikweni kwa mlingo.

Kapangidwe ka cartridge sikuloleza zomwe zili mkati mwake kusakanikirana ndi zina insulin, komanso kudzazitsanso katoniyo.

Mukamagwiritsa ntchito Mbale, emulsion imasonkhanitsidwa pamenepo syringe insulin, yomwe voliyumu imafanana ndi potengera insulin (mwachitsanzo 100 IU / 1 ml insulin = 1 ml syringe) ndikuthandizira malinga ndi malingaliro a dokotala.

Masingano ndi zolembera sizingagwiritsenso ntchito kapena kugwiritsa ntchito ena. Mbale ndi ma cartridge amagwiritsidwa ntchito kamodzi mpaka mankhwala atamalizidwa, ndikuchotsedwa.

Mwina kuyambitsa kwa Humulin NPH kuphatikiza Humulin Wokhazikika.

Bwanji, pofuna kuti asalowe kulowa m'botolo insulin kuchitapo kanthu kwanthawi yayitali, woyamba kuyimba mu syringe insulin zochita zazifupi.

Kusakaniza uku ndikulimbikitsidwa kuti kuyambitsidwe mukangosakaniza. Kuti mupeze mlingo woyenera wa awiri insulin mutha kugwiritsa ntchito ma syringe osiyanasiyana.

Bongo

Mwakutero, palibe mankhwala osokoneza bongo a Humulin NPH. Zizindikiro zimawerengedwa. hypoglycemialimodzi ndi kuchuluka thukutaulesi tachycardiamutu womvera khungu mawonekedwe kunjenjemera, chisokonezokusanza.

Nthawi zina, zizindikiro zam'mbuyomu hypoglycemia (shuga yayitali kapena kuwongolera kwake kwambiri) kumasintha.

Mawonekedwe hypoglycemia wofatsa, nthawi zambiri umayimitsidwa pakamwa shuga kapena shuga (dextrose) M'tsogolomu, mungafunike kusintha zakudya, mlingo insulin kapena zolimbitsa thupi.

Kusintha hypoglycemia kusasamala kochitika kumachitika ndi jekeseni wa SC kapena / m glucagon, ndi makamwa owonjezereka chakudya.

Mawonekedwe owopsa hypoglycemia atha kutsagana nawo chikomokere, zovuta zamitsempha kapena spasmsomwe atulutsidwa ndi jakisoni wa iv shuga wolimbas (dextrose) kapena s / c kapena kuyambitsa glucagon. M'tsogolomo, kuti tipewe kubwerezanso kwa zizindikiro, chakudya cha anthu ambiri chakudya.

Kuchita

Kuphatikiza Ntchito Mowamankhwala a hypoglycemic (pamlomo), salicylatesMao zoletsa sulfonamides, opanga beta Sinthani zotsatira za hypoglycemic za Humulin NPH.

Reserpine, Clonidine ndi opanga beta amatha mafuta a hypoglycemia.

Malonda ogulitsa

Mankhwala amafunika kugula insulini.

Malo osungira

Mankhwala a Humulin NPH amasungidwa mufiriji (2 - 8 ° C), osazizira.

Mankhwala omwe amagwiritsidwa ntchito mukatoni kapena mu botolo amatha kusungidwa kwa masiku 28 firiji.

Tsiku lotha ntchito

Ndi kusungidwa koyenera - miyezi 24.

Malangizo apadera

Sankhani pakufunika kosamutsira wodwala wina kapena mtundu wina insulin kungakhale dokotala. Kusintha uku kuyenera kuchitika motsogozedwa mwamphamvu ndi zomwe wodwala akuchita.

Sinthani mtundu ntchito ya insulin(Nthawi zonse, M3 ndi zina zotero

,, mitundu yake (munthu, nkhumba, analog) kapena njira yopangira (chinyama chiyambi kapena Kubwereza kwa DNAAngafunike kusintha kwa mankhwalawa, koyamba pakukonzekera komanso munthawi ya chithandizo, pang'onopang'ono pakadutsa milungu kapena miyezi.

Insulin kudalira kumatha kuchepera kulephera kwa aimpsozodabwisa gren adrenalchithokomiro chiwindi.

At kupsinjika mtima ndipo ndi ma pathologies ena, pakhoza kukhala chosowa chowonjezera cha insulin.

Nthawi zina kusintha kwa mankhwalawa ndikofunikira pakusintha Zakudya kapena kuchuluka zolimbitsa thupi.

Mwa odwala ena, ngati atagwiritsidwa ntchito insulin yamunthuzizindikiro zam'mbuyomu hypoglycemia ikhoza kukhala yosiyana ndi yomwe imagwiritsidwa ntchito nyama insulin kapena kukhala osatchulidwa.

Matenda a plasma kuchuluka kwa shugachifukwa champhamvu mankhwala a insulinzimatsogolera pakutha kwa zonse kapena mawonekedwe ena hypoglycemiazomwe muyenera kumuuza wodwalayo.

Zizindikiro zakuyamba hypoglycemia Itha kuyeretsedwa kapena kusinthidwa kuti muzigwiritsa ntchito limodzi opanga beta, matenda ashuga a m'mimba kapena kutalika matenda ashuga.

Nthawi zina, kwanuko matupi awo onse mawonetsedwe atha kukhala pazifukwa zosayenderana ndi zovuta za mankhwalawa (i.e. kupweteketsa khungu chifukwa chogwiritsa ntchito yothandizira kuyeretsa kapena jakisoni wosayenera).

Kaŵirikaŵiri, kagwiridwe ka ziwonetsero zina kangafunike chithandizo chamomwemonso (kuchititsa kukakamira kapena insulin m'malo).

Chifukwa cha zomwe zingachitike hypoglycemia kusamala konse kuyenera kuchitika mukamagwira ntchito zowopsa ndikuyendetsa galimoto.

Mwadzidzidzi insulin-Ferein,
Monotard HM,
Insulin-Ferein ChSP,
Monotard MC,
Humodar B,
Pensulin SS.

Dongosolo la makonzedwe, kuchuluka ndi kuchuluka kwa jakisoni kumatsimikiziridwa payekha ndi dokotala, mogwirizana ndi zofunikira za wodwalayo.

Mimba (ndi mkaka wa m'mawere)

Komanso, zakudya komanso / kapena kusintha kwa mankhwalawa kungafunike panthawi yake nyere.

Mukamasankha insulin Dokotala amayenera kuwunika wodwalayo kuchokera kumbali zonse ndikusankha mankhwala omwe ali oyenera kwa wodwalayo.

Pankhaniyi, mankhwalawa Humulin NPH amawonetsa zotsatira zabwino zamankhwala ndipo angagwiritsidwe ntchito kwakanthawi.

Mtengo Humulin NPH, komwe mugule

Mutha kugula Humulin NPH pa avareji: botolo la 10 ml No. 1 - 550 ma ruble, 3 ml ma cartridge a No. 5 - 1500 rubles.

Humulin NPH kuyimitsidwa 100 IU / ml 10 ml Lilly Eli Lilly & Company
Humulin NPH kuyimitsidwa 100 IU / ml 3 ml 5 ma PC.

Humulin NPH kuyimitsidwa 100ME / ml 3ml No. 5 makatoni + QuickPenEli Lilly & cholembera makina
Humulin NPH kuyimitsidwa kwa 100ME / ml 3ml No. 5 makatiriji Eli Lilly & Company
Humulin NPH kuyimitsidwa 100MU / ml 10ml No. 1 botoloEli Lilly & Company

Gulani mu sitolo yathu cholembera cholembera HumaPen Luxura - DiaMarka

Kukula kwa mlingo ndi gawo limodzi.

Cholembera cha syringe chimapangidwa ndi Eli Lilly ndipo ndi choyenera kwa ma insulini onse a wopanga:

Yang'anani! Chophimba cha HumaPen Luxura Syringe cholembanso ndi insulin.Mtengo wa cholembera ichi cha Biosulin ndiwomveka.

Komanso, pachiwopsezo chanu komanso pachiwopsezo chanu, mutha kugwiritsa ntchito cholembera ichi pa insulin "pa Apidra.
Maukadaulo apadera Sringe zolembera HumaPen Luxura

Kapangidwe ka ma penfoles a 3 ml (mayunitsi 300).
Gawo lochepetsetsa ndi gawo la insulin ya 1 unit.
Mlingo wapamwamba mu seti imodzi ndi 60 magawo.
Miyeso: 165x25x23 mm
Kulemera: 30g.

Zambiri za cholembera HumaPen Luxura:

Kuwonekera ndi kuwongolera mawu polemba gawo lililonse la insulin
Kutha kuletsa mlingo
Makhalidwe abwino kwambiri "pamsonkhanowu
Maonekedwe okongola komanso osangalatsa
Chovuta cholimba, chapamwamba kwambiri chomwe chimakwaniritsa chogwiramo pachokha.

Humapen Luxura Syringe chole
Mlanduwu (pali malo owerengera singano zapamwamba ndi katemera wa insulin)
Malangizo mu Russian

Humulin: malangizo ogwiritsira ntchito, mtengo, ndemanga ndi analogi

Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD

Ikupezeka onse ngati mtundu wa kuyimitsidwa kwa kayendetsedwe ka ma subcutaneous mu mbale ("Humulin" NPH ndi MZ), komanso mawonekedwe a makatoni okhala ndi cholembera (“Humulin Regular”). Kuyimitsidwa kwa oyang'anira sc kumamasulidwa mu 10 ml. Mtundu wa kuyimitsidwa ndi mitambo kapena milky, voliyumu ya 100 IU / ml mu cholembera cha 1.5 kapena 3 ml. M'katoni, masipu 5 a syringes omwe ali papulasitiki.

Kuphatikizikako kumaphatikizapo insulin (yaumunthu kapena ya biphasic, 100 IU / ml), zotuluka: metacresol, glycerol, protamine sulfate, phenol, zinc oxide, sodium hydrogen phosphate, madzi a jakisoni.

Opanga INN

Dzinalo lapadziko lonse lapansi ndi insulin-isophan (umisiri wa chibadwa cha anthu).

Imapangidwa makamaka ndi Lilly France SAAS, France.

Zoyimira ku Russia: "Eli Lilly Vostok S.A."

"Humulin" imasiyana pamtengo malinga ndi mtundu wa kumasulidwa: mabotolo kuchokera ku ma ruble 300-500, makatoni kuchokera ku ruble 800-1000. Mtengo ungasiyane m'mizinda yosiyanasiyana.

Zotsatira za pharmacological

"Humulin NPH" ndi insulin yowonjezera ya anthu. Imayendetsa kagayidwe ka glucose, imachepetsa mulingo wake ndikuwonjezera mphamvu yake m'maselo ndi minyewa, ndikufulumizitsa mapuloteni a anabolism. Kutumiza kwa glucose kumisempha kuchokera m'magazi kumachulukitsa, komwe kukhazikika kwake kumatsika.

Ilinso ndi zotsatira za anabolic komanso anti-catabolic pamatipi amthupi. Ndi kukonzekera kwa insulin.

The achire zotsatira kuwonetseredwa 1 ora pambuyo makonzedwe, hypoglycemic - kumatenga maola 18, nsonga kukonzekera - pambuyo 2 maola mpaka maola 8 kuchokera nthawi yochoka.

Humulin pafupipafupi ndikulinganiza mwachidule insulin.

Humulin MZ ndi chisakanizo cha insulin yochepa komanso yapakati. Imayendetsa mphamvu yotsitsa shuga mthupi. Imadziwonekera yokha theka la ola pambuyo pa jakisoni, kutalika ndi maola 18-24, kutengera mawonekedwe a thupi ndi zinthu zina zakunja (zakudya, zolimbitsa thupi).

Pharmacokinetics

Mlingo wa mawonetseredwe a zotsatira zake umadalira malo a jakisoni, mlingo womwe umayendetsedwa ndi mankhwala osankhidwa. Imagawidwa mosiyanasiyana munsiyo, simalowerera mkaka wa m'mawere ndi placenta. Imawonongeka makamaka mu impso ndi chiwindi ndi enzyme insulinase, yomwe imatsitsidwa ndi impso.

Mtundu wodwala matenda a shuga.
Mimba mwa odwala omwe ali ndi matenda ashuga oopsa (okhala ndi vuto la kudya).

Contraindication

hypoglycemiazomwe zikuwoneka pano
Hypersensitivity pa zosakaniza za Humulin NPH.

Zotsatira zoyipa

Zotsatira zazikulu zoyambira hypoglycemia, pomwe pamachitika zovuta kwambiri kumatha kuyambitsa kusazindikira komanso kufa (kawirikawiri).

Palinso kuthekera kochepa kakapangidwe lipodystrophy.

Thupi lawo siligwirizana ndi chikhalidwe:

Zomwe thupi lawo siliganiza:

kutupa kapena kuyabwa m'dera la jakisoni (nthawi zambiri amayima pakangotha milungu yochepa),
Hyperemia.

Malangizo ogwiritsira ntchito Humulin NPH

Mlingo wa Humulin NPH amasankhidwa payekha, molingana ndi mulingo wa glycemia wodwala.

Jakisoni wambiri wa Humulin NPH amaletsedwa!

Kukonzekera ndi kutsata kwa Humulin NPH

Ndi cholinga insulin resuspension, musanagwiritse ntchito, Mbale ndi makatiriji a kukonzekera kwa Humulin NPH ndikulimbikitsidwa kuti ziguduzidwe kanthawi kokwanira m'manja khumi ndikugwedezeka kambiri nthawi imodzi (kutembenuka mpaka 180 °) mpaka kukonzekera kumapeza mawonekedwe osalala pafupi ndi mkaka kapena madzi amchere. Kugwedeza mankhwalawa mwamphamvu sikuyenera kutero, chifukwa chithovu chopangidwa mwanjira iyi chimatha kusokoneza kusankha kwenikweni kwa mlingo.

Kapangidwe ka cartridge sikuloleza zomwe zili mkati mwake kusakanikirana ndi zina insulin, komanso kudzazitsanso katoniyo.

Mukamagwiritsa ntchito Mbale, emulsion imasonkhanitsidwa pamenepo syringe insulin, yomwe voliyumu imafanana ndi potengera insulin (mwachitsanzo 100 IU / 1 ml insulin = 1 ml syringe) ndikuthandizira malinga ndi malingaliro a dokotala.

Masingano ndi zolembera sizingagwiritsenso ntchito kapena kugwiritsa ntchito ena. Mbale ndi ma cartridge amagwiritsidwa ntchito kamodzi mpaka mankhwala atamalizidwa, ndikuchotsedwa.

Mwina kuyambitsa kwa Humulin NPH kuphatikiza Humulin Wokhazikika.

Bwanji, pofuna kuti asalowe kulowa m'botolo insulin kuchitapo kanthu kwanthawi yayitali, woyamba kuyimba mu syringe insulin zochita zazifupi.

Kusakaniza uku ndikulimbikitsidwa kuti kuyambitsidwe mukangosakaniza. Kuti mupeze mlingo woyenera wa awiri insulin mutha kugwiritsa ntchito ma syringe osiyanasiyana.

Bongo

Mwakutero, palibe mankhwala osokoneza bongo a Humulin NPH.Zizindikiro zimawerengedwa. hypoglycemialimodzi ndi kuchuluka thukutaulesi tachycardiamutu womvera khungu mawonekedwe kunjenjemera, chisokonezokusanza.

Nthawi zina, zizindikiro zam'mbuyomu hypoglycemia (shuga yayitali kapena kuwongolera kwake kwambiri) kumasintha.

Kusintha hypoglycemia kusasamala kochitika kumachitika ndi jekeseni wa SC kapena / m glucagon, ndi makamwa owonjezereka chakudya.

Kuchita

Kuphatikiza Ntchito Mowamankhwala a hypoglycemic (pamlomo), salicylatesMao zoletsa sulfonamides, opanga beta Sinthani zotsatira za hypoglycemic za Humulin NPH.

Reserpine, Clonidine ndi opanga beta amatha mafuta a hypoglycemia.

Malonda ogulitsa

Mankhwala amafunika kugula insulini.

Malo osungira

Mankhwala a Humulin NPH amasungidwa mufiriji (2 - 8 ° C), osazizira.

Mankhwala omwe amagwiritsidwa ntchito mukatoni kapena mu botolo amatha kusungidwa kwa masiku 28 firiji.

Tsiku lotha ntchito

Ndi kusungidwa koyenera - miyezi 24.

Malangizo apadera

Sankhani pakufunika kosamutsira wodwala wina kapena mtundu wina insulin kungakhale dokotala. Kusintha uku kuyenera kuchitika motsogozedwa mwamphamvu ndi zomwe wodwala akuchita.

Sinthani mtundu ntchito ya insulin(Nthawi zonse, M3 ndi zina zotero

Insulin kudalira kumatha kuchepera kulephera kwa aimpsozodabwisa gren adrenalchithokomiro chiwindi.

At kupsinjika mtima ndipo ndi ma pathologies ena, pakhoza kukhala chosowa chowonjezera cha insulin.

Nthawi zina kusintha kwa mankhwalawa ndikofunikira pakusintha Zakudya kapena kuchuluka zolimbitsa thupi.

Matenda a plasma kuchuluka kwa shugachifukwa champhamvu mankhwala a insulinzimatsogolera pakutha kwa zonse kapena mawonekedwe ena hypoglycemiazomwe muyenera kumuuza wodwalayo.

Zizindikiro zakuyamba hypoglycemia Itha kuyeretsedwa kapena kusinthidwa kuti muzigwiritsa ntchito limodzi opanga beta, matenda ashuga a m'mimba kapena kutalika matenda ashuga.

Kaŵirikaŵiri, kagwiridwe ka ziwonetsero zina kangafunike chithandizo chamomwemonso (kuchititsa kukakamira kapena insulin m'malo).

Chifukwa cha zomwe zingachitike hypoglycemia kusamala konse kuyenera kuchitika mukamagwira ntchito zowopsa ndikuyendetsa galimoto.

Mwadzidzidzi insulin-Ferein,
Monotard HM,
Insulin-Ferein ChSP,
Monotard MC,
Humodar B,
Pensulin SS.

Dongosolo la makonzedwe, kuchuluka ndi kuchuluka kwa jakisoni kumatsimikiziridwa payekha ndi dokotala, mogwirizana ndi zofunikira za wodwalayo.

Mimba (ndi mkaka wa m'mawere)

Komanso, zakudya komanso / kapena kusintha kwa mankhwalawa kungafunike panthawi yake nyere.

Mukamasankha insulin Dokotala amayenera kuwunika wodwalayo kuchokera kumbali zonse ndikusankha mankhwala omwe ali oyenera kwa wodwalayo.

Pankhaniyi, mankhwalawa Humulin NPH amawonetsa zotsatira zabwino zamankhwala ndipo angagwiritsidwe ntchito kwakanthawi.

Mtengo Humulin NPH, komwe mugule

Mutha kugula Humulin NPH pa avareji: botolo la 10 ml No. 1 - 550 ma ruble, 3 ml ma cartridge a No. 5 - 1500 rubles.

Humulin NPH kuyimitsidwa 100 IU / ml 10 ml Lilly Eli Lilly & Company
Humulin NPH kuyimitsidwa 100 IU / ml 3 ml 5 ma PC.

Humulin NPH kuyimitsidwa 100ME / ml 3ml No. 5 makatoni + QuickPenEli Lilly & cholembera makina
Humulin NPH kuyimitsidwa kwa 100ME / ml 3ml No. 5 makatiriji Eli Lilly & Company
Humulin NPH kuyimitsidwa 100MU / ml 10ml No. 1 botoloEli Lilly & Company

Gulani mu sitolo yathu cholembera cholembera HumaPen Luxura - DiaMarka

Kukula kwa mlingo ndi gawo limodzi.

Cholembera cha syringe chimapangidwa ndi Eli Lilly ndipo ndi choyenera kwa ma insulini onse a wopanga:

Yang'anani! Chophimba cha HumaPen Luxura Syringe cholembanso ndi insulin. Mtengo wa cholembera ichi cha Biosulin ndiwomveka.

Komanso, pachiwopsezo chanu komanso pachiwopsezo chanu, mutha kugwiritsa ntchito cholembera ichi pa insulin "pa Apidra.
Maukadaulo apadera Sringe zolembera HumaPen Luxura

Kapangidwe ka ma penfoles a 3 ml (mayunitsi 300).
Gawo lochepetsetsa ndi gawo la insulin ya 1 unit.
Mlingo wapamwamba mu seti imodzi ndi 60 magawo.
Miyeso: 165x25x23 mm
Kulemera: 30g.

Zambiri za cholembera HumaPen Luxura:

Kuwonekera ndi kuwongolera mawu polemba gawo lililonse la insulin
Kutha kuletsa mlingo
Makhalidwe abwino kwambiri "pamsonkhanowu
Maonekedwe okongola komanso osangalatsa
Chovuta cholimba, chapamwamba kwambiri chomwe chimakwaniritsa chogwiramo pachokha.

Humapen Luxura Syringe chole
Mlanduwu (pali malo owerengera singano zapamwamba ndi katemera wa insulin)
Malangizo mu Russian

Humulin: malangizo ogwiritsira ntchito, mtengo, ndemanga ndi analogi

Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD

Opanga INN

Dzinalo lapadziko lonse lapansi ndi insulin-isophan (umisiri wa chibadwa cha anthu).

Imapangidwa makamaka ndi Lilly France SAAS, France.

Zoyimira ku Russia: "Eli Lilly Vostok S.A."

"Humulin" imasiyana pamtengo malinga ndi mtundu wa kumasulidwa: mabotolo kuchokera ku ma ruble 300-500, makatoni kuchokera ku ruble 800-1000. Mtengo ungasiyane m'mizinda yosiyanasiyana.

Zotsatira za pharmacological

Ilinso ndi zotsatira za anabolic komanso anti-catabolic pamatipi amthupi. Ndi kukonzekera kwa insulin.

The achire zotsatira kuwonetseredwa 1 ora pambuyo makonzedwe, hypoglycemic - kumatenga maola 18, nsonga kukonzekera - pambuyo 2 maola mpaka maola 8 kuchokera nthawi yochoka.

Humulin pafupipafupi ndikulinganiza mwachidule insulin.

Pharmacokinetics

Mtundu wodwala matenda a shuga.
Mimba mwa odwala omwe ali ndi matenda ashuga oopsa (okhala ndi vuto la kudya).

Contraindication

Hypoglycemia (m'munsi mwake mulingo wa 3.3-5,5 mmol / L m'magazi).
Hypersensitivity kumagawo.

Malangizo ogwiritsira ntchito (mlingo)

Dokotala amakhazikitsa mlingo, kutengera mtundu wa glycemia malinga ndi zotsatira za mayeso. Amathandizidwa mosavuta kapena m'njira zamitsempha 1-2 patsiku. Masamba obayira ndi am'mimba, matako, mapewa, kapena m'chiuno. Popewa lipodystrophy, muyenera kusintha malowo nthawi zonse kuti asabwerezenso kangapo pamwezi.

Pambuyo pa jekeseni, khungu silingasunthe. Pewani kulowa m'mitsempha yamagazi kuti hematoma isapangidwe. Wodwala aliyense ayenera kuphunzitsidwa ndi dokotala kapena namwino pakayendetsedwe koyenera ka mankhwala ndi chitetezo.

Mimba komanso kuyamwa

Ndikofunikira kudziwitsa dokotala yemwe akukonzekera za kukhala ndi pakati kapena nthawi yake isanakwane. Izi zikufunika kukonza mankhwalawo.

Kufunika kwa insulin kwa odwala matendawa omwe ali ndi matenda ashuga nthawi zambiri kumachepetsedwa mu trimester yoyamba, koma kumawonjezeka kwachiwiri komanso kwachitatu. Pa mkaka wa m`mawere, chithandizo ndi kusintha zakudya zimafunikanso.

Pazonse, Humulin sanawonetse mutagenic mu mayeso onse, choncho chithandizo cha amayi ndi chothandiza kwa mwana.

Biosulin kapena mwachangu: chabwino ndi chiti?

Izi ndi zinthu zomwe zimapezeka panjira ya biosynthetic (DNA recombinant) chifukwa cha kusintha kwa enzymatic kwa porcine insulin. Ali pafupi kwambiri ndi insulin yaumunthu. Onse ali ndi zotsatira zakanthawi kochepa, chifukwa chake nkovuta kunena kuti wabwino ndi uti. Chisankho pazakusankhidwa chimachitika ndi katswiri.

Fananizani ndi fanizo

Kuti mumve mankhwala omwe ndi oyenera kugwiritsa ntchito, lingalirani za analogues.

Mtengo: yankho kuchokera ku ma ruble 370, ma cartridge kuchokera ku 800 rubles.

Zochita: hypoglycemic wothandizira wa nthawi yayitali.

Ubwino: zochepa zotsutsana ndi zoyipa zochepa, zoyenera kwa amayi apakati komanso oyamwitsa.

Sangagwiritsidwe ntchito molumikizana ndi thiazolidinediones, popeza pali chiopsezo cholephera kwamtima, komanso choperekedwa ndi intramuscularly, pokhapokha. Khalid. Zogwira ntchito: insulin yaumunthu. Wopanga: "Novo Nordisk A / S Novo-Alle, DK-2880" Baggswerd, Denmark.

Mtengo: yankho kuchokera ku ma ruble 390, makatoni - kuchokera ku ruble 800.

Zochita: hypoglycemic chinthu chaifupi.

Ubwino: Wofunika kwa ana ndi achinyamata, amayi oyembekezera komanso oyembekezera, amatha kuthandizidwa pang'onopang'ono komanso m'njira zamkati, osavuta kugwiritsa ntchito kunja kwa nyumba.

Zitha kugwiritsidwa ntchito ndi zinthu zogwirizana, sizingagwiritsidwe ntchito limodzi ndi thiazolidatediones.

Olga: "Ndi chosavuta kwambiri kuti imabwera ngati ma cartridge. Apongozi anu akhala ali ndi matenda a shuga kwa nthawi yayitali, muyenera kuwunika pafupipafupi momwe angathere komanso kupatsa jakisoni osati kunyumba. Atakhutira ndi zotsatirazi, akumva bwino kwambiri. "

Svetlana: “Anamuuza Humulin ali ndi pakati. Zinali zovuta kuvomereza, mwadzidzidzi zimakhudza mwana. Koma adotolo adatsimikizira kuti awa ndi mankhwala otetezeka, ngakhale ana amafunsidwa. Ndipo chowonadi chimathandiza, shuga adakhala wabwinobwino, osakhala ndi zotsatirapo zake! ”

Igor: “Ndili ndi matenda ashuga 1. Ndikokwera mtengo kuchiza mulimonse, chifukwa ndikufuna mankhwala atithandizire. Adotolo adalemba "Humulin", ndakhala ndikugwiritsa ntchito kwa miyezi isanu ndi umodzi tsopano. Kuyimitsidwa ndikotsika mtengo, koma ndikosavuta kwa ine kugwiritsa ntchito ma cartridge. Zambiri, ndakhutira: Ndachepetsa shuga ndipo mtengo wake ukunena. ”

Pomaliza

"Humulin" ndi yothandiza kwambiri komanso yotetezeka ku chithandizo cha matenda a shuga. Kugwiritsa ntchito mankhwalawa kumathandizira kukhala ndi shuga wabwinobwino wamagazi ndipo kumawononga nthawi yochepa pobayira. Anthu ambiri omwe amagwiritsa ntchito mankhwalawa amangosiya ndemanga zabwino, zomwe zimasonyezanso kudalirika kwake komanso mtundu wake.

Nph humulin, isofan insulin ya odwala matenda ashuga

Ku Russia, anthu pafupifupi 3 miliyoni ochokera ku dziko lonselo akudwala matenda opatsirana padziko lonse lapansi - matenda ashuga.

Nthawi zambiri, anthu odwala matenda ashuga nthawi zambiri amapita ku endocrinologists ndikudziyimira pawokha magazi.

Chiwerengero chikuwonjezereka tsiku ndi tsiku, ndipo tsiku lililonse matendawa amalembedwa mwa anthu 200, ndipo 90% yamatenda a shuga.

Mu magawo oyamba, mankhwala amkamwa amagwiritsidwa ntchito kutsitsa shuga, ndipo chithandizo cha insulin chimatha. Mwa njira, nthawi zambiri chithandizo cha insulin chimayamba mochedwa kwambiri, ngakhale pali mankhwala ambiri okhala ndi mankhwalawa. Mwambiri, mankhwala ochepetsa magazi ngati jakisoni amatha kugawidwa m'magulu atatu.

kopitilira muyeso kochepa
zochita zazifupi
nthawi yayitali yochita.

Mafuta a insulin yaumunthu:

zochita zosakanikirana (analogue + human),
zosakanikirana za sing'anga ndi zazifupi akuchita insulin.

Kukonzekera kwa Neutral Protamine Hagedorn

Kukonzekera kumapangidwa ndi makampani osiyanasiyana, ndipo ndi dokotala yekha yemwe ayenera kusankha yoyenera.

Palibe chifukwa chake musalowe m'malo mankhwalawo, chifukwa izi zitha kupangitsa kuti thupi liziganiza mosasamala, chifukwa cha kuchuluka kwa mankhwala omwe sanasinthe.

Ngakhale gawo laling'ono lothandizanso lingathe kuyambitsa mavuto ambiri. Othandizira angapo a protamine Hagedorn omwe satchulidwa pagome amayimira mankhwala omwe amagwiritsidwa ntchito kwambiri ku Russia.

Dziko	Wopanga kampani	Dzina lamankhwala
Denmark	NovoNordisk	PROTAFAN® NM Protafan® NM Penfill®
Egypt USA	LIGI GUPI ELI LILLY & Company	HUMULIN® NPH
Germany	SANOFI-AVENTIS Deutschland	INSUMAN B BASAL GT

Kodi pali kusiyana kotani pakati pa NPH insulin ndi insulin ina?

Mankhwala a insulin ndi protamine ndi mankhwala osokoneza bongo apakatikati. Chidule chachilendo chimachokera ku dzina lachi Latin loti Neutral Protamine Hagedorn. Ku Russia, mutha kupeza mayina ena osagulitsa a mankhwalawa (PCR kapena isofan).

Mankhwalawa amapezeka ngati kuyimitsidwa kwa ma sc makonzedwe olimba a insulin. Chifukwa chake, kukonzekera kotsalira kumakhala pansi pa khungu kwa nthawi yayitali, kulowa m'magazi pang'onopang'ono. Pankhani imeneyi, insulin, yomwe imatchedwa npx, imagwira ntchito kwa maola 12-16, yomwe imakhala yotalikirapo 2-3 kuposa insulin ina yamunthu.

Kuti mukwaniritse zopindulitsa kwambiri za NPH insulin, ndikofunikira kutsatira njira yochitira jakisoni wa sc. Kafukufuku wasonyeza kuti ndi 9% yokha ya odwala onse omwe amagwiritsa ntchito isofan molondola omwe amalowetsa muyezo wofunikira, pomwe ena onse samanyalanyaza njira yoyenera.

Ma NPH ambiri amapangidwa ndi makampani osiyanasiyana azamankhwala omwe amapanga makatoni othandizira insulin, komabe, si makampani onse omwe amawona kulondola kwa mankhwalawa popereka mankhwala.

Kukonzekera kwa NPH kumasiyanitsidwa pakati pawo, kumagawana mu insulin ya nkhumba ndi anthu. Mukasinthana ndi mankhwala amtundu wina, kapangidwe kamankhwala kamene kamalowa m'magazi amasintha, chifukwa ma amino acid omwe amapezeka mwa anthu ndi porcine insulin ndi osiyana.

Zisonyezero zakugwiritsa ntchito Humulin

Humulin ndi yoyenera kugwiritsidwa ntchito ndi amayi oyembekezera omwe amadalira insulin omwe ali ndi mbiri ya matenda a shuga a 2. A endocrinologist atha kukuwuzani jakisoni wa humulin kwa nthawi yoyamba matenda a shuga amapezeka mwa wodwala, kapena m'malo mwa mankhwala ena (ngati akuwonetsedwa), kuti apitirize insulin.

Njira Yoyambira Molondola

Kukhazikitsidwa kwa mtundu uliwonse wa insulin kuyenera kukhala kwakanthawi, kapena kutengera deta ya glucometer.
Tsamba la jakisoni liyenera kusinthidwa nthawi iliyonse.
Mbale yokhala ndi mankhwala a NPH kapena cholembera chokhala ndi katemera wa humulin iyenera kutembenuka kwathunthu maulendo 20 musanagwiritse ntchito, koma osagwedezeka.
Ngati mugwiritsa ntchito humulin mu vial, ndiye kuti simungagwiritse ntchito singano imodzi (singano) pobwereza kayendetsedwe kake, lamuloli limagwiranso ntchito pa zolembera za syringe.
Osagwiritsa ntchito ma insulin ndi ma syringe enanso a odwala ena.
Singano yochokera ku cholembera imayenera kuchotsedwa nthawi yomweyo.
Ngati mbali ya insulin ikuyenda kuchokera pakhungu musadzabayira jakisoni wa humulin kachiwiri.
Ngati mumakonda kumwa mowa, kapena mowa umapukuta jakisoni, ndiye dikirani mpaka mowawo utatha khungu.
Ngati makhiristu oyera ofanana ndi mawonekedwe achisanu aonekera m'makoma a botolo, simungathe kuwagwiritsa ntchito.
Humulin Regular ndi NPH imatha kusakanikirana mu syringe imodzi, pomwe Humulin yokhazikika imayenera kulembedwa.Lamuloli limalembedwa pokhapokha ndi humulin, ndizosatheka kusakaniza mankhwala a magulu ena mu syringe imodzi ya insulin.

Kuchepetsa ndi pakati

Amayi ena omwe ali ndi matenda ashuga posachedwa amaganiza za ana.Molondola, momwe ndingathere, ngati insulin imagwiritsidwa ntchito kukonza milingo ya shuga, makamaka, humulin yodziwika ndi NPH.

Amayi ambiri amanyalanyaza thanzi lawo, kusamalira kuti kuwopsa kwa mankhwalawa sikuyambitsa masinthidwe mwa mwana. Komabe, ndizosatheka kunyalanyaza kumwa mankhwala kuti adzivulaze, chifukwa izi zingasokoneze kukula kwa mwana.

Ndikofunika kukonzekereratu za mimba isanakwane, ndi kudziwitsa adotolo osati zitangochitika, komanso pokonzekera. Munthawi iliyonse, kuyendera kwa endocrinologist ndikofunikira, chifukwa ndiamene amayenera kuthana ndi kusintha kwa mankhwalawa. Mzimayi akuyenera kukhala okonzekera kuti nthawi yoyamba mlingo wa insulin uzikhala wotsika kuposa masiku onse, ndipo chachiwiri ndi chachitatu chiziwonjezeka.