Bagomet - mankhwala omwe amachepetsa shuga la magazi

Malinga ndi malangizo a Bagomet ndi mankhwala a hypoglycemic ochokera pagulu la Biguanide. Mankhwala a Bagomet amalepheretsa shuga m'magazi, amathandizira kuchepetsa kuyamwa kwa glucose m'matumbo. Mankhwalawa amathandizira kugwiritsidwa ntchito kwina kwa glucose, kukulitsa chidwi cha zimakhala kuti insulin. Ndemanga za Bagomet zimatsimikizira kuti mankhwalawa amatithandizanso kusintha komanso kuchepetsa thupi.

Chizindikiro Bagomet

Malinga ndi malangizo a Bagomet, madokotala amalamula odwala omwe ali ndi mtundu wa 2 matenda a shuga popanda ketoacidosis. Bagomet imatengedwa ngati mankhwala othandizira pakudya ndi chithandizo cha mankhwala a sulfonylureas apezeka kuti samathandiza. Bagomet ya mankhwala imatengedwa mu monotherapy kapena kuphatikiza ndi insulin kapena othandizira ena a hypoglycemic.

Mlingo ndi makonzedwe

Malinga ndi malangizo Bagomet anatengedwa pakamwa. Tiyenera kudziwa kuti kuchuluka kwa mankhwalawa kuyenera kuyikidwa ndi dokotala payekhapayekha, kutengera kuchuluka kwa shuga m'magazi a wodwalayo. Bagomet imatha kutengedwa musanadye komanso pambuyo chakudya.

Ngati odwala satenga insulin, mapiritsi a Bagomet amatha kuledzera kawiri pa tsiku 1 gramu. Ndikofunika kumwa mankhwalawa m'masiku atatu oyamba a mankhwalawa. Mutha kumwa monga chiwembu china - piritsi limodzi la Bagomet 500 mg katatu patsiku. Kuyambira tsiku lachinayi, dongosolo limasinthasintha, muyenera kumwa mapiritsi awiri a Bagomet katatu patsiku. Kotero mpaka tsiku la 14, kuphatikiza. Pambuyo pa izi, kuyesedwa kwa magazi ndi mkodzo kwa glucose kumatengedwa. Kuyambira tsiku la 15, mlingo wa kumwa mapiritsi a Bagomet umasinthidwa. Mlingo watsiku ndi tsiku uyenera kukhala 1-2 g.

Ngati wodwala ali ndi mapiritsi a 850 mg a Bagomet, ayenera kumwedwa kawiri pa tsiku, kamodzi. Mukuyenera kudziwa kuti mpaka magalamu atatu a Bagomet ayenera kumwedwa nthawi zambiri patsiku.

Ndi nthawi yomweyo makonzedwe a Bagomet ndi insulin, wodwalayo ayenera kuchepetsa mlingo wa insulin. Malangizo olondola pamilandu yolandiridwa motere ayenera kuperekedwa ndi dokotala.

Zotsatira zoyipa Bagomet

Ndemanga za Bagomet akuti mankhwalawa amatha kuyambitsa mavuto osiyanasiyana. Wodwala amatha kusanza komanso kutsekula m'mimba, kupweteka kwam'mimba akamagwiritsa ntchito mankhwalawa. Nthawi zina kugwiritsa ntchito Bagomet kumayambitsa kukoma kwa chitsulo mkamwa. Mankhwalawa atha kupatsanso mavuto ena: kuchepa magazi, kuchepa kwamphamvu pakudya, hypoglycemia. Kugwiritsa ntchito kwa nthawi yaitali kwa Bagomet kumayambitsa vitamini B12 wambiri m'thupi la munthu.

Contraindication

Malinga ndi malangizo a Bagomet sangatengedwe ndi hypersensitivity kuti metformin. Mankhwala ali contraindised mu aimpso kulephera, matenda ashuga, precoma, ketoacidosis. Bagomet simumatengedwanso kupuma komanso kulephera kwa mtima, kugunda kwamtima, chithokomiro cha pachimake. Bagomet imaphatikizidwa mwapadera ndi uchidakwa woperewera. Komanso, madokotala samalangiza kumwa mankhwalawa pambuyo povulala ndikuchita opaleshoni yayikulu. Ndemanga ya Bagomet ikuti sikulimbikitsidwa kumwa mankhwalawa kwa odwala atatha zaka makumi asanu ndi limodzi.

Zotsatira zamtundu wa Bagomet

Bagomet ndi mankhwala a hypoglycemic omwe amachepetsa shuga komanso kuthamanga kwake pakudya. Mankhwala sasokoneza kapangidwe ka insulin. Zina mwazotsatira zoyipa za hypoglycemia sizinakhazikike. Kuthekera kwa mankhwalawa kumawonekera pambuyo pa kulepheretsa kwa glycogenolysis ndi gluconeogenesis, komwe kumayambitsa kulepheretsa kwa glycogen m'chiwindi. Mankhwalawa amathandizira kuti maselo agwire ndikutulutsa glucose, amathandizira chidwi cha zotumphukira zomwe zimalowa mu mahomoni, komanso zimalepheretsa kuyamwa kwa ma carbohydrate ndi makoma amatumbo.

Bagomet imawonjezera mphamvu ya enzyme yomwe imathandizira kapangidwe ka glycogen, imawonjezera kuthekera kwa mayendedwe a membrane a glucose. Mankhwalawa amakongoletsa kagayidwe ka lipid - ndi matenda amtundu wa 2 pali mwayi wonenepa.

Bagomet ikufananiridwa bwino ndi omwe amagwirizana nawo pankhani ya kuthamanga kwambiri komanso kotheratu.

Mukamwetsa, mankhwalawo amatengedwa nthawi yomweyo kuchokera m'mimba, chimbudzi chambiri chimafika patatha maola awiri ndi theka. Imachepetsa mwayi wamafuta omwe amapezeka pakudya. Zizindikiro za Bagomet za bioavailability ndizokwera mpaka 60% ya kuchuluka kwa mankhwala omwe amaperekedwa ku ziwalo.

Malinga ndi zotsatira za kafukufuku wa pharmacokinetic, titha kunena kuti mankhwalawa amasunthira minofu mosavuta, ndikufalikira m'madzi a m'magazi. Zigawo za mankhwala sizigwirizana ndi mapuloteni, zimatha kulowa m'magazi ofiira, koma m'magazi ndizochepa kwambiri poyerekeza ndi plasma.

Kafukufuku watsimikizira kuti mankhwalawa samapangidwira mu thupi - impso zimakongoletsa momwe zidalili. Poterepa, theka-moyo ndi maola asanu ndi limodzi ndi theka. Kutuluka kwa Bagomet kumamukwiyitsa ndi kusefukira kwa glomerular kusefukira ndi impso chiberekero, motero, odwala onse omwe ali ndi aimpso a pathologies ali pachiwopsezo.

Hafu ya moyo imachulukitsidwa, zomwe zikutanthauza kuti pamakhala chiopsezo cha kuchuluka kwa mankhwala.

Zizindikiro ndi njira yogwiritsira ntchito

Bagomet imapangidwira zochizira odwala matenda ashuga omwe ali ndi mtundu wodziyimira pawokha wa matenda komanso kunenepa kwambiri (pakalibe ketoacidosis komanso yankho losakwanira lithandizo la sulfonylureas).

Kugwiritsa ntchito kwa Bagomet ndikotheka kokha malinga ndi malingaliro a endocrinologist, amene afotokozere za chithandizo cha mankhwala poganizira kuuma kwa matendawo komanso thanzi la wodwalayo.

Mankhwalawa adapangira kuti azigwiritsidwa ntchito mkati. Finyani piritsi lonse ndi madzi. Izi nthawi zambiri zimachitika ndi chakudya kapena zitatha. Mlingo woyambirira ndi 500-100 mg / tsiku, kutengera mlingo wa glycemia. Mutha kusintha mankhwalawa pokhapokha masabata awiri atatha kudya ndikuwunika mawonetsedwe a glycemic.

Ngati dokotala sanapange chisankho payekha pokhudzana ndi wodwalayo, ndiye kuti muyezo wowerengeka wothandizidwa ndi 1500 mpaka 2000 mg. Ndikosatheka kupitilira muyeso wokwanira. Ngati mankhwalawa akukhumudwitsa chopondacho, mutha kuthana ndi chizolowezi chatsiku ndi tsiku katatu.

Ndi zovuta mankhwala "Bagomet kuphatikiza insulin kukonzekera", muyezo Mlingo ndi 1500 mg / tsiku. Mapiritsi okhala ndi mphamvu yayitali, mulingo woyenera tsiku ndi tsiku ndi 850 mg -1000 mg. Ndi kulekerera kwabwinobwino, amayima pamalo okwanira 1700 mg / tsiku., Malire - 2550 mg / tsiku. Ndi chithandizo chovuta ndi mankhwala ena ochepetsa shuga, piritsi limodzi (850 mg kapena 100 mg) limayikidwa.

Mukukula, Bagomet imatenga zosaposa 1000 mg / tsiku. Mutha kupereka mankhwala kwaana azaka zopitilira 10. Ana, komanso achikulire, ayenera kuyambiranso maphunziro a 500-850 mg / tsiku. Muubwana, pazipita tsiku lililonse ndi 2000 mg.

Zotsatira zoyipa

Mwambiri, mankhwalawa amaloledwa ndi odwala ambiri, koma, monga mankhwala aliwonse, pamakhala zotsatirapo zake.

Kuyang'ana kwapadera kunawonetsa kuti Bagomet sikupangitsa mutagenicity, carcinogenicity ndi teratogenicity. Zake zosagwirizana ndi ntchito yobereka zimatsimikiziridwa.

Zotsatira Zogwiritsa Ntchito Mankhwala

Kugwiritsa ntchito kwa hypoglycemic kwa Bagomet kumatheka chifukwa cha mankhwala a shufanilamides, insulin, acarbose, anti-yotupa, ACE ndi mao inhibitors, oxytetracycline, β-blockers.

Glucocorticosteroids, GOK, epinephrine, glucagon, mahomoni a chithokomiro, sympathomimetics, thiazide ndi "loop" diuretics, phenothiazine ndi nicotinic acid zotumphukira zimalepheretsa ntchito yake.

Kuchotsa kwa Bagomet ku ziwalo kumaletsedwa ndi cimetidine. Mphamvu yakutsitsa kwa Coumarin imachokera mu Bagomet.

Kumwa moledzeretsa kamodzi kumakwiyitsa lactic acidosis. Mawonetseredwe ake ndi kutsika kwa kutentha kwa thupi, myalgia, kusapeza bwino pamimba, kusokonezeka kwa dyspeptic, dyspnea, kusokonezeka kwa chopondapo, kukomoka. Pokayikira koyamba, wolakwiridwayo amagonekedwa m'chipatala ndipo matendawa amafotokozedwa pofufuza kuchuluka kwa lactate mu ziwalo ndi minyewa. Njira yothandiza kwambiri yoyeretsera thupi la poizoni ndi hemodialysis. Malinga ndi zikuwonetsa, imathandizidwa ndi dalili.

Zizindikiro zosokoneza bongo

Ngati Mlingo wa Bagomet uli pamtunda wovomerezeka, lactic acidosis yokhala ndi zotsatirapo zoyipa kwambiri ngakhale kufa. Zofanana zimachitika chifukwa cha kuchuluka kwa mankhwalawa mthupi lomwe lili ndi mavuto ndi impso. Mavuto amakula patangotha ​​maola ochepa ndipo amakhala ndi zodziwika bwino:

• Matenda a Dyspeptic
• Hypothermia,
• Kuphwanya miyambo yamatumbo,
• Ululu pamimba
• Myalgia
• Kutaya kulumikizana
• Kukomoka ndi matenda ashuga.

Ngati gawo limodzi la zizindikiro zomwe zatchulidwa zawoneka, Bagomet iyenera kuchotsedwa mwachangu, ndipo wolakwiridwayo ayenera kuchipatala.

Kutulutsa mawonekedwe, kapangidwe kake, malo osungira

Mapiritsi amatha kukhala ndi mawonekedwe ndi mitundu yosiyanasiyana, kutengera mulingo: yoyera, yozungulira komanso yotupa - 500 mg aliyense, mwanjira ya makapisozi - 850 mg wa buluu wamtundu ndi 1000 mg mu yoyera. Omalizirawo akhala ndi katundu wautali. Gawo la mafomu kumasulidwa ndi mzere wogawa ndi logo ya wopanga, womangidwa pamapiritsi onse.

Piritsi limodzi lili ndi 500 mpaka 100 mg ya yogwira pophika metformin hydrochloride kuphatikiza mawonekedwe a croscarmellose sodium, povidone, stearic acid, chimanga wowuma, lactose monohydrate.

Zipangizo zothandizira zoyambira ndi mankhwala ziyenera kuyikidwa pamalo osavomerezeka ndi ana, pamtunda wofika mpaka 25 ° C. Sungani Bagomet zosaposa zaka ziwiri.

Mgwirizano ndi fanizo la mankhwala

Mgwirizano wofanizira wa Bagomet umaphatikizapo mankhwala omwe gululi (mankhwala amkati mwa antidiabetic) ndi zigawo zomwe zimagwira.

Ma analogi a Bagomet ndi mankhwala omwe matenda kapena vuto limodzi limangofanana mu umboni, mwanjira iyi mtundu wachiwiri wa matenda ashuga.

1. Avandia
2. Apidra
3. Baeta
4. Glemaz
5. Glidiab
6. Glucobay,
7. Nyama,
8. Lymphomyozot,
9. Levemir Penfill,
10. Levemir Flekspen,
11. Multisorb,
12. Metamine
13. NovoFormin,
14. Phuli
15. Fomu,
16. Fomu.

Ndi chithandizo chovuta ndi mankhwala ena omwe ali ndi vuto lofananalo, ndikofunikira kulingalira za hypoglycemia. Mankhwalawa amatha kusokoneza mgwirizano ndikuchepetsa mphamvu ya psychomotor, chifukwa chake mukamagwira ntchito moyenera kapena mukuyendetsa, ndibwino kuti musamamwe mankhwalawo. Kugwiritsira ntchito kwa Bagomet kumaphatikizapo kutsata kovomerezeka ndi zakudya zama carb zotsika zomwe zimayendetsa kudya kwa mafuta m'magazi.

Ndemanga za Bagomet

Za mankhwala a Bagomet, ndemanga za madokotala ndizabwino. Malinga ndi akatswiri, kumwa mankhwala otchuka kotere kumapangitsa kuti magazi azitha kwa maola 12. Mwayi wotere umamuwonetsa maubwino ena: mutha kuchepetsa pafupipafupi kumwa mankhwalawo, kusintha kayendedwe ka metabolic. Nthawi yomweyo, kuyamwa kwa zinthu zogwira ntchito m'mimba kumakonzedwa ndipo chiwopsezo chokhala ndi zovuta zimachepa.

Odwala nawonso adazindikira kupezeka kwa mankhwalawa: pa Bagomet mtengo (850 mg ma CD) ndi ma ruble a 180-230 okha mapiritsi 60. Tulutsani mankhwalawo m'mafakisoni ndi mankhwala.

Kufotokozera kwa mankhwalawa sikungakhale chitsogozo chogwiritsidwa ntchito. Musanagule, muyenera kufunsa wa endocrinologist, ndipo musanamwe mankhwala a Bagomet, werengani malangizo omwe angagwiritsidwe ntchito ndi wopanga. Zambiri zokhudzana ndi Bagomet zimaperekedwa kuti zidziwidwe bwino ndi kuthekera kwake ndipo sikuti ndizitsogozo zodzichiritsa nokha. Njira yeniyeni yolandirira chithandizo, poganizira kuopsa kwa matenda ashuga, matenda ofanana komanso kuchuluka kwa odwala matenda ashuga, amatha kupangidwa ndi katswiri.