Momwe mungatengere Orsoten - malangizo ogwiritsira ntchito kuwonda

Makapisozi awiri a hypromellose okhala ndi utoto woyera kapena wachikasu, wokhala ndi ma MicRoganu (kapena osakanikirana ndi ma Microganules ndi ufa) wa mtundu woyera kapena pafupifupi woyera. Ma meshes, makatoni

Yogwira ntchito:

Orsoten zipatso zofananira (momwe zimagwiritsidwa ntchito ngati 120 mg ya orlistat)

Othandizira:

Microcrystalline cellulose, titanium dioxide, hypromellose, madzi oyeretsedwa

Mlingo ndi makonzedwe

Pa mlingo umodzi wa mankhwalawa, tikulimbikitsidwa kutenga kapisozi ndi mlingo wa 120 mg yogwira ntchito.

Momwe mungatenge Orsoten kuti muchepetse thupi? Mankhwalawa amayenera kumwedwa pakamwa katatu patsiku, asanadye kaye, asanadye chakudya kapena ola limodzi, ndikutsukidwa ndi madzi. Kuchulukitsa mlingo wa mankhwala musanagwiritse ntchito katatu patsiku sikugwira ntchito. Ngati pali zakudya zosachepera zitatu, kapena zakudya sizikhala ndi mafuta, ndiye kuti kumwa mapiritsi a Orsoten sikofunikira.

Osamwa mankhwalawa kwa zaka zopitilira ziwiri. Ngati mukumwa mankhwala a Orsoten kwa masabata 12 pamankhwala osavomerezeka simuwonekere, muyenera kusiya kumwa mankhwalawo. Zotsatira zakuchepa zimawerengedwa kuti ndizochepera 5% ya kulemera koyambirira.

Mankhwala si wowerengeka, otetezeka kuchepetsa thupi ndipo amamulembera yekha dokotala, ngati akuwonetsedwa. Tengani Orsoten chifukwa cha kuchepa thupi amaloledwa kwa okalamba, anthu omwe ali ndi vuto la chiwindi. Kusintha kwa Mlingo sikofunikira.

Bongo

Nkhani za bongo za Orsoten sizifotokozedwa. Zotsatira zoyipa zamagetsi zomwe zimagwiritsidwa ntchito mu mlingo wa 800 mg, Mlingo wambiri mpaka 400 mg tsiku lililonse, chifukwa masiku 15 sanapezeke.

Palibe kuwonjezereka kwa zotsatira zoyipa za mankhwalawa kunapezeka pamene odwala omwe ali ndi vuto la kunenepa kwambiri amatenga katatu patsiku mlingo wa 240 mg wa orlistat kwa miyezi isanu ndi umodzi.

Ngati mankhwala osokoneza bongo a mankhwalawa, ndikofunikira kuyang'ana wodwala tsiku lonse.

Contraindication

Malinga ndi malangizo ogwiritsira ntchito, Orsoten sayenera kutengedwa ngati:

• Hypersensitivity pamagawo a mankhwala,
• kusokoneza matumbo mayamwidwe (aakulu malabsorption),
• mimba ndi mkaka wa m`mawere
• cholestasis (kuchepa kwa katulutsidwe ka bile m'mimba yaying'ono),
• pansi pa zaka 18 (palibe maphunziro).

Malangizo apadera

1. Chipangizochi chikugwirizana ndi: kuchepetsa chiopsezo cha matenda okhudzana ndi kunenepa kwambiri (hypercholesterolemia, hyperinsulinemia, Type 2 shuga mellitus), kuchepetsa kuchuluka kwa mafuta a visceral, kuwongolera nthawi yayitali thupi (kuchepetsa, kusunga ndi kupewa kunenepa),
2. Kuchepetsa thupi kuchokera ku chithandizo cha Orsoten kumabweretsa chindapusa chabwino cha kagayidwe kazakudya kwa anthu omwe ali ndi matenda amtundu II. Chifukwa cha izi, ndizotheka kuchepetsa mlingo wa mankhwala a hypoglycemic.
3. Kugwiritsidwa ntchito kwa Orsoten kumachepetsa kuyamwa kwa mavitamini osungunuka a mafuta A, E, K, D chifukwa chake, odwala amalimbikitsidwa kuti atenge maofesi a multivitamin.
4. Ndikofunika kutsatira malangizo pazakudya: odwala ayenera kulandira zakudya zopatsa thanzi, zopatsa mphamvu komanso zopatsa mphamvu zamafuta tsiku lililonse zosaposa 30%. Zakudya zamafuta zimayenera kugawidwa mosiyanasiyana pakati pa chakudya. Kutsatira zakudya zamafuta ochepa kumachepetsa mavuto.
5. Pakakhala zoletsa kugwiritsa ntchito zakudya zomwe zili ndi mafuta ambiri, komanso zakudya zopatsa mphamvu zopitilira 2000 patsiku, mwayi wokhala ndi zotsatirapo zamatumbo umawonjezeka.

Mtengo wa mankhwalawo m'masitolo am'mishonga

Kodi Orsoten amawononga ndalama zingati pachipatala? Mtengo wa mankhwalawa umatengera kuchuluka kwa mankhwalawo mu kapisozi imodzi komanso kuchuluka kwa makapisozi omwe ali phukusi. Mutha kugula Orsoten Slim (60 mg) pamtengo wa ma ruble 400, mtengo wa Orsoten 120 mg ndi ma ruble 700 ma 21 makapisozi mpaka 2500 phukusi lokhala ndi makapisozi 80. M'masitolo osiyanasiyana, mtengo wa Orsoten ndiwosiyana.

Zolemba za Orsoten

Polimbana ndi mapaundi owonjezera, zotsatirazi ndizotsika mtengo za Orsoten:

1. Xenical. Mankhwala ochokera pagulu lofananalo la mankhwala omwe ali ndi Orsoten ali ndi orlistat.
2. Xenalten. Copy ya Orsoten, ili ndi orlistat. Gastrointestinal lipase inhibitor.
3. Orsotin Slim. Mlingo wa Orsoten wokhala ndi zinthu zotsika mu kapisozi imodzi (60 mg).
4. Allie. Lipase inhibitor. Makina ochitapo kanthu ndi chifukwa chophwanya kuphwanya mafuta kuchokera ku chakudya komanso kuchepa kwa mayamwidwe awo.

Kuchepetsa thupi pazotsatira zoonda

Alexandra, wazaka 43: Ndidayesera kumwa mankhwala Orsoten ndi analogue yamtengo wapatali - Xenical. Malinga ndikuwona, Orsoten ndiwothandiza kwambiri, ngakhale akuwunika madokotala. Ndi kukana zakudya zamafuta ndi zotsekemera, mchaka pakudya ndi mankhwala, adataya makilogalamu 12 osachita masewera olimbitsa thupi.

Valentina, wazaka 35: Nditawerenga zowerengera za kuchepa thupi za Orsoten, ndidayesetsa kumwa mankhwalawa kwa miyezi 4. Ndataya 8 kg. Paphwandopo, ndinakumana ndi zinthu zosasangalatsa, koma zotsatira zake zinali zoyenera kuvutika. Kenako ndiyesa ndi Orsotin wochepa.

Wachiroma, wazaka 27: Chifukwa cha thanzi langa, ndiyenera kuyamba kumwa Orsoten. Mwezi woyamba ndinachotsa makilogalamu 4, ndiye kuti kuchepa thupi kunayima. Ndidawonjezera kulimbitsa thupi, ndipo miyezi itatu yotsatila ndidataya kilogalamu imodzi 6.

Orsoten kwa kuwonda. Momwe mungatengere orsoten pazotsatira zabwino kwambiri?

Chilichonse chimagwirizanitsidwa ndi chiwopsezo cha matenda amtima wamagazi chifukwa chokhudzana ndi cholesterol yambiri m'magazi.

Anthu amamwa mafuta ochulukirapo komanso mafuta ochulukitsa, zinthu zambiri zomalizidwa zopangidwa modabwitsa, amakhala ndi moyo wokhazikika, womwe sungawononge thupi.

Ku Slovenia, mankhwalawa "Orsoten" adapangidwa, omwe amapangidwira odwala omwe ali ndi kunenepa kwambiri kapena onenepa kwambiri. Fomu yotulutsira ndi 21, 42, 84 makapisozi pa paketi iliyonse, 120 mg. Mankhwalawa amapezeka m'mapiritsi ndi makapisozi. Kodi amagwira ntchito bwanji? The yogwira mankhwala - orlistat - akulowa m'mimba thirakiti ndipo pang'ono zimasokoneza kuyamwa kwa mafuta. Izi ndichifukwa choti mankhwalawa amachita pa enzyme lipase, yomwe imaphwanya mafuta.

Popeza lipase imaphwanya mafuta m'mimba ndi kapamba, Orsoten amakhala ndi mphamvu zochepa mthupi, osapitirira m'mimba. Kenako, mafuta osagawanika amachotsedwa mw thupi mwachilengedwe. Chifukwa cha makina amatsenga awa, mafuta osungunula osakanikirana amagwiritsidwa ntchito mwachangu ndi thupi, zomwe zimathandiza kuchepetsa kuchuluka ndi kulemera.

Phindu la mankhwalawa limawonetsedwa m'njira zambiri. Kuphatikiza kwa "Orsoten" pakuchepetsa thupi ndikuti zinthu zake sizimayikidwa m'magazi, koma zimangokhala m'matumbo, mothandizidwa ndi zomwe amachotsa. Mankhwalawa amatha kutengedwa ndi odwala omwe ali ndi matenda ashuga, ndipo odwala samangolephera thupi, komanso amathandizira kuchepetsa kupita patsogolo kwa matenda ashuga.

Kuphatikiza pakukhathamiritsa kwa kayendetsedwe ka mtima, Orsoten amakhudza bwino kuchuluka kwa kuthamanga kwa magazi, kugwira ntchito kwa endocrine ndi machitidwe am'mimba.

Kodi mutenge Orsoten? Rimage regimen ndi yosavuta kwambiri ndipo sikutanthauza kuyeserera kowonjezera: 1 kapisozi katatu patsiku. Ndipo tsopano tawonani: imwani mankhwalawa musanadye, zakudya, kapena ola limodzi mutatha kudya! Ngati mwaphonya chakudya, ndiye osamwa piritsi, ingolumikizani ndipo ndizo zonse, palibe chomwe chimachitika. Mutu wina wofunikira: nthawi iliyonse chakudya chikakhala choyambirira, ndiye kuti mumakhala wandiweyani.

Mukangodya kadzutsa, chakudya chamadzulo ndi chakudya chamadzulo, imwani kapisozi 1 ya Orsoten. Ngati chakudya chanu chiribe mafuta, ndiye kuti simuyenera kudya.

Ngakhale kuti Orsoten amadziwika kuti ndi mankhwala omwe amathandizira thupi, musaiwale kuti, monga mankhwala aliwonse, ali ndi zotsutsana. Makamaka, simungathe kugwiritsa ntchito:

• - anthu omwe ali ndi mbiri ya cholestasis,
• - azimayi oyembekezera
• - achinyamata osakwana zaka 18,
• - kwa amayi achichepere omwe akuyamwitsa,
• - pokhapokha ngati pali tsankho la munthu pazigawo za mankhwala.

Chifukwa chiyani ndizowopsa kutenga "Orsoten" ndi cholestasis? Chowonadi ndi chakuti ndi matenda, mapangidwe abwinobwino a bile amasokonezedwa, chomwe ndi chinthu chofunikira pakukonza mafuta omwe amalandidwa m'thupi ndi chakudya. Ndi cholestasis, ndulu imadzuka (pang'ono kapena kwathunthu). Chithandizo chokwanira ndichofunika, chifukwa pakadali pano muyenera kuyiwala za Orsoten.

Mwina simukudziwa za kukhalapo kwa zizindikiro za cholestasis yayitali pang'ono, chifukwa chake musanatenge Orsoten, muyenera kufunsa dokotala.

Kuphatikiza apo, monga mankhwala aliwonse, Orsoten ali ndi mavuto. Zotsatira zoyipa zitha kuonedwa koyambirira kwa makonzedwe, zimawoneka ngati:

• - mipweya
• - m'mimba,
• - chopondapo,
• - kukakamiza pafupipafupi kutulutsa matumbo.

Nthawi zina odwala amawona kugawanika kwamafuta ndi ndowe, makamaka pakachitika kuti piritsi linasowa kapena pamene mankhwalawo sanaledzeretsedwe pachakudya chachikulu.

Nthawi zina, zotsatira zosasangalatsa kuchokera ku dongosolo lamkati lamanjenje, monga kumverera kovuta kwa nkhawa komanso kupweteka pamutu, zitha kuonedwa. Mwa anthu omwe amakonda kupindika, pakhungu, khungu limayamba.

Zotsatira zoyipa zimatha kuchitika nthawi zina, monga:

• - kumangokhalira kutopa,
• - Zizindikiro ngati chimfine
• - nyengo zopweteka.

Ambiri mwa mavuto awa adzatha mukakumbukira momwe mungamwere Orsoten molondola, kapena thupi likagwirizana ndi mankhwalawo. Ngati sizidutsa, ndikofunikira kusiya mankhwalawo kapena kusankha analogi.

Mankhwala okwanira ofanana ndi zomwe Orsoten apanga. Ena mwa iwo ndi okwera mtengo kwambiri, ena, m'malo mwake, ndi otsika mtengo.

Mutha kuyesa kugwiritsa ntchito Xenical, yomwe ilinso ndi orlistat. Mwina adokotala angakulangizeni kuti musankhe Xenalten, komwe ndi buku la Orsoten. Kapena mudzalandira mankhwala a Orsoten Slim pharmacy - machitidwe ake ndi ofanana, amangokhala ndi zinthu zochepa, motero, mwina ndi bwino kuti pakhale matenda ena.

Makampani ogulitsa mankhwala amapanganso Alli, mankhwala omwe amathandizira kuchepetsa kuyamwa kwa mafuta.

Zomwe ziyenera kusankhidwa ndizomwe zili kwa inu ndi dokotala.

Tsopano mukudziwa momwe mungatengere Orsoten, koma kuti mupeze zotsatira zabwino zolemetsa, muyenera kugwiritsa ntchito malingaliro athu ena. Chifukwa chake, poyambira, musaganize kuti mankhwalawa ndi panacea. Zimangoletsa pang'ono kuyamwa kwa mafuta. Mukamagwiritsa ntchito pokhapokha, zotsatira zake sizikhala zabwino kwambiri, ndipo zolemerazo zimatha kubwerera. Kumbukirani kuti kuti muchepetse kunenepa, muyenera njira yayikulu yothetsera vutoli.

1. Choyambirira komanso chofunikira: pitani zakudya zamagulu ochepa zopatsa mphamvu. Palibenso chifukwa chanjala, ingochepetsa zakudya zanu zopatsa mphamvu, zakudya zingapo zoyipa komanso zakudya zosavuta.
2. Chachiwiri: kuchita masewera. Ziribe kanthu kuti zingamveke bwanji, koma m'moyo wa mkazi wamakono palibe kuyenda kokwanira, komwe sikwabwino thanzi. Zochita zilizonse zolimbitsa thupi zitha kukhala ndi phindu pa vuto lanu. Zochita zakunja monga kuthamanga, kupalasa njinga kapena kukwera miyendo ndizolandilidwa kwambiri. Pumirani m'mwamba ndikusangalala ndi zinthu zosangalatsa mthupi.

"Orsoten" adawonekera pamsika wathu osati kalekale, koma adapeza kale mafani ake. Anthu ambiri amasangalala kuwona zabwino. Tiyeni timvere mawu a omwe adayesera kale zochita za Orsoten pa iwo.

“Ndidatha kutaya makilogalamu 8 m'miyezi itatu. Mankhwala abwino. ”

"Adasangalatsanso makilogalamu 12, ngakhale asanaphunzitse zolimbitsa thupi komanso kudya zakudya zapadera."

"M'mwezi umodzi wokha, ma kilogalamu anayi adatha, koma kulemera kwake kudafikira nthawi imodzi. Ndinafunika kuwonjezera kulimba - zinthu zinayamba: posakhalitsa ma kilos 6 "anasungunuka".

"Minus 3 kg paulendo uliwonse. Koma panali zotsatirapo zina: kusanja mafuta, kumasulidwa mosafunikira kwa mafuta. Tsitsilo linayamba kulocha, kenako anayambiranso. ”

"Zotsatira zake zinali zosangalatsa: kulemera kwake kunatsika ndi makilogalamu 15 paulendo uliwonse. Zabwino kwambiri! ”

Mwambiri, pali ndemanga zabwino za Orsoten. Koma gwiritsani ntchito molondola ndipo musaiwale za malamulo ovomerezera: mutha kumwa kwa zaka 2, osati nthawi zonse. Onetsetsani kuti mwawonana ndi dokotala ndikuwerenga phukusi. Ndipo, zowonadi, onjezerani zakudya ndi zolimbitsa thupi pamaphunzirowa: kulemera kwanu kumachoka ndizosangalatsa!

Masiku ano, mankhwala osiyanasiyana ochepetsa thupi atchuka kwambiri, osati pakati pa osewera okha, komanso anthu wamba omwe akuyesera kuti achepetse thupi. Imodzi mwa mankhwalawa ndi Orsoten. Chida ichi cholinga chake ndikuletsa kuyamwa kwa mafuta ndi thupi, chifukwa chake munthu amayamba kutaya ma kilogalamu odedwa.

Chomwe chimagwiritsa ntchito mankhwalawa ndi orlistat, chomwe chimagwira pamilomo ya lipase yomwe imayambitsa kuphwanya mafuta. Zotsatira zake, mafuta omwe amalowa mthupi samaphwasuka ndipo samamwa, koma amamuchotsa ndi ndowe.

Kuwunika kwa Orsoten kumakhala kwabwino kwambiri, chifukwa mphamvu ya mankhwalawa imayamba pambuyo pa maola 24, ndipo magawo ake omwe amagwira ntchito samayikidwa m'magazi ndipo samakhudza njira zomwe zimachitika ziwalo zina ndi minyewa. Imafotokozedwanso mwachilengedwe masiku 1-2.

Kuzindikirika kwa mankhwalawa ndikuwonekanso kuti kayendetsedwe kake ndizotheka ngakhale ndi matenda monga matenda a shuga. Monga lamulo, ndi iyo, zinthu zambiri zakuchepera zimapangidwa chifukwa cha kukhalapo kwa shuga ambiri m'mapiritsi. Koma ku Orsoten sichoncho, chifukwa cha gulu la anthu odwala matenda ashuga, mankhwalawa ali otetezeka kwathunthu.

Orsoten amapezeka mu mawonekedwe amodzi okha - m'mabotolo. Ndipo kuti tikwaniritse bwino kwambiri kuchokera ku kayendetsedwe kake, ndikofunikira kumwa mankhwalawa pokhapokha ndikudya bwino komanso kuchita masewera olimbitsa thupi.

Ndizofunikira kudziwa kuti mitundu iwiri yamankhwala igulitsidwa - "Orsoten" ndi "Orsoten Slim". Ziri pafupi kufanana. Kusiyana kwa iwo kumakhala mu mlingo. Orsoten amangokhala ndi 200 mg yogwira ntchito ya orlistat, ndipo Orsotin amangokhala 60 mg yokha.

Mankhwala osalala ambiri amakhala ndi subitromine, yomwe siivomerezedwa ndi ochita masewera olimbitsa thupi, chifukwa imagwira pamafupa a ubongo, motero dongosolo lonse lamanjenje. Orsoten imakhala ndi orlistat, yomwe si ya psychotropic ndipo imayambitsa zotsatira zoyipa zochepa.

Njira yochitira izi ndi motere. Mankhwala akalowa m'mimba ndi duodenum, imayamba kuletsa kupanga lipase, yomwe imalimbikitsa kusweka, mayamwidwe ndikusonyezedwa kwamafuta m'matumbo a subcutaneous.

Kuchita izi kumabweretsa kuti mafuta omwe amalowa m'mimba ndi chakudya sayakidwa ndipo amatumizidwa nthawi yomweyo m'matumbo. Ndipo kale kudzera mu izo amachotsedwa m'thupi, titero kunena kwake, mwa mawonekedwe osasiyanitsidwa.

Komabe, ndikofunikira kudziwa kuti magwiridwe antchito a Orsoten angawonedwe kokha ndi zakudya zama calorie ochepa. Kupatula apo, mankhwalawa amapangidwira kuthandiza munthu kuti achepetse thupi, koma sangatero.

Ngati mumamwa zakumwa zoledzeretsa ndikuyamba kudya zakudya zamafuta ambiri mukamamwa Orsoten, pamakhala chiwopsezo chachikulu chokhala ndi vuto logaya chakudya m'mimba.Izi zimatha kuyambitsa matenda otsegula m'mimba komanso tulo, tomwe timayambitsa kudontha.

Ndizofunikanso kudziwa kuti Orsoten samakhudza mayamwidwe am'madzi, kuphatikiza osavuta. Ngati mkati mwake mumadya zakudya zamafuta ochepa, zimasinthidwa kukhala mafuta ndikuzisunga munthaka. Ndipo mankhwalawa, mwatsoka, sangathe kuletsa njirayi.

Orsoten ndi mankhwala opangidwa makamaka kwa anthu onenepa kwambiri. Monga mankhwala aliwonse, Orsoten ali ndi zotsutsana.
Sikulimbikitsidwa kwa anthu omwe ali ndi vuto lililonse la chida ichi. Amadziwikiranso anthu omwe ali ndi cholestasis komanso malabsorption aakulu.

Kuphatikiza apo, mankhwalawa ali ndi zoletsa zaka. Sizingatengedwe kwa anthu ochepera zaka zambiri. Komanso, kugwiritsidwa ntchito kwake sikulimbikitsidwa kwa amayi omwe ali pachiwopsezo cha kubereka ndi kuyamwa, popeza mphamvu za Orsoten pagulu lino la anthu sizinaphunzire konse.

Monga mankhwala aliwonse, Orsoten amakhalanso ndi zovuta. Amawonedwa nthawi zambiri magawo oyambawo kumwa mankhwalawo, ndiye kuti mphamvu zake zimachepa ndipo pakapita nthawi zimazimiririka.

Zotsatira zoyipa kwambiri ndikuwoneka kwamafuta ochulukirapo mu chopondapo. Komabe, simuyenera kuwopa iwo, chifukwa, poganizira mphamvu ya mankhwalawa (kuchotsa mafuta), izi ndizobwinobwino.

Koma limodzi ndi zotsatirapo zake, Zizindikiro zina zosasangalatsa zimatha kuonedwa. Mwachitsanzo, kutsegula m'mimba ndi kusakhazikika kwa fecal, komwe kumabweretsa zosasangalatsa m'moyo wamunthu. Vuto lakuchuluka kwakhansa limapezekanso m'matumbo athu onse (m'mimba, matumbo).

Ngakhale mukumwa Orsoten, chiopsezo chotenga matenda, mawonekedwe a kutopa komanso kusamba kwa msambo kumawonjezeka. Palinso gulu la anthu omwe omwe amamwa mankhwalawa amayambitsa ziwopsezo zamkati ndikuwonjezera chiwindi ntchito.

Ngati mungaganize zothandizidwa ndi mankhwalawa, ndiye kuti muyenera kutsatira malingaliro ena omwe angathandize kusintha kwa Orsoten.

Orsoten: malangizo ogwiritsira ntchito, mtengo, ndemanga, kuchepa thupi, analogi

Kunenepa kwambiri ndi vuto lalikulu lapadziko lonse. Ndi kunenepa kwambiri, kuchuluka kwake kumaposa Noma pofika 20-30%.

Ichi ndi matenda oopsa omwe amakhala ndi vuto lililonse mthupi, ziwalo zofunika. Mphamvu ya minofu ndi mafupa, manjenje, mtima komanso mtima, komanso chitetezo chokwanira zimavutika ndi mafuta ochulukirapo.

Psyche yamunthu siyimilira, komwe kulemera kumapitilira kukula. Ambiri amataya mtima, kuzolowera kuvala mapaundi odana, kumakhala moyo wopanda malire.

Kwa iwo omwe ali okonzekera kumenyera nkhondo komanso thanzi labwino, amadalira moyo wautali komanso wachimwemwe, mankhwala apangidwa Orsoten.

Zimalepheretsa kuwonongeka kwa mafuta kuchokera ku chakudya. Kugwiritsa ntchito mphamvu kumachitika chifukwa cha mafuta ake omwe amasungidwa, omwe amakhala pansi pakhungu pamimba, m'chiuno, matako.

Kuti muchepetse 20-30 makilogalamu owonjezera thupi, nthawi zambiri sikokwanira kuti anthu azidya moyenera ndikusuntha kwambiri.

Pankhaniyi, madokotala amalimbikitsa kumwa mankhwala apadera. Gulu lawo limachitika mogwirizana ndi mfundo zoyenera kuchitapo.

Mankhwala ena amachepetsa kulakalaka, kuletsa chidwi chofuna kudya. Ena - amakhala ndi mphamvu ya kukoka thupi ndi kukodzetsa thupi, chifukwa chamomwe munthu amalemera. Chachitatucho chimalepheretsa kuyamwa kwa mafuta ndi chakudya chamafuta, ndipo mphamvu zonse zimagwiritsidwa ntchito chifukwa cha zomwe zidapangidwa kale.

Pali mitundu itatu ya mankhwalawa yochepetsa thupi, ali ndi lingaliro lina:

1. Pewani chilakolako chogwiritsa ntchito ubongo.
2. Pewani kuyamwa kwa mafuta ndi chakudya chamafuta m'mimba.
3. Amakhala ndi mankhwala othandizira komanso okodzetsa.

Orsoten ili ndi lipase inhibitor orlistat ndi zigawo zothandizira.

Gulani Orsoten siovuta. Imagulitsidwa ku malo ogulitsa mankhwala, kwa ogulitsa, ogawa, pa intaneti, pama social network.

Mtengo muma pharmacies umatengera komwe wagulitsa, mtengo wogulira.

Mtundu wa "lite" wocheperako nthawi zonse umakhala wotsika mtengo kuposa mankhwala wokhala ndi mlingo waukulu. Kuchuluka kwa ma CD kumakhalanso kosiyanasiyana. Pali zosankha za 42, 60, 84 zidutswa.

Mtengo wa mankhwala ochepetsa thupi umakhala m'mazenera a ruble 2 mpaka 3000.

Mankhwala amapatsidwa kunenepa kwambiri. Ndi bwino kuyamba kugwiritsa ntchito mankhwala ochepetsetsa - Orsotin Slim.

Ngati kugwira ntchito kwake sikokwanira, ndiye kuti wodwalayo amasinthanso Orsoten - njira yokhala ndi kuchuluka kwa zinthu zomwe zili m'mapiritsi.

Kugwiritsa ntchito mankhwalawa ndikomveka matendalimodzi ndi kulemera. Pakati pawo - matenda ashuga, atherosclerosis, matenda oopsa ndi ena.

Ndi iwo, pali kuphwanya mafuta kagayidwe, kuchuluka kwakukulu kwa shuga ndi mafuta m'thupi.

Kafukufuku wachipatala adatsimikizira kuti Orsoten siosuta, chifukwa chake, angagwiritsidwe ntchito kwa nthawi yayitali.

Nthawi yovomerezeka yoyambira ndiyambira miyezi ingapo mpaka zaka ziwiri. Pankhaniyi, kuwongolera zolemetsa kumachitika popanda kufunika kowonjezera mlingo. Ngati chizolowezi chimaperekedwa, ndiye kuti zochulukazo zimachotsedwa m'thupi pambuyo masiku 5 mwanjira yachilengedwe.

Pofika nthawi, Orsoten amakhala mthupi kuyambira maola 48 mpaka 72. Chiwerengero cha tsiku ndi tsiku cha makapisozi zimatengera zakudya.

Malinga ndi chiwembu chokhacho, Orsoten amatengedwa pachakudya chilichonse, ndiye kuti katatu.

Ngati zakudya kapena zakudya zomwe zilibe mafuta, ndiye kuti samamwa mankhwalawo.

Malamulo akuluakulu omwe amatenga Orsoten kuti achepetse thupi:

• kudya calorie kuyenera kukhala kwapakati, ndiko kuti, mumagulu a 1200-1600 kcal patsiku,
• kutsimikizika kwakukulu m'zakudya kuyenera kukhala pamapuloteni ndi mafuta owonjezera pang'onopang'ono,
• kuphatikiza ndi Orsoten, bioavailability yamafuta osungunuka a mavitamini A, D, E, K yafupika,
• kukulitsa kwa kutsegula m'mimba pogwiritsa ntchito njira zakulera pakamwa kumawonetsa kuchepa kwa mphamvu yawo,
• kuphatikiza ndi mankhwala ena kumachitika moyang'aniridwa ndi achipatala pafupipafupi.

Orsoten chosokoneza ndi cholowa BMI zosakwana 25 mayunitsi akakhala ofunikira. Pankhaniyi, mutha kuchita popanda mapiritsi, kungochepetsa mphamvu ya kalori, kupatula zakudya ndi mbale zina kuchokera pamenyu.

Kuwonjezeka kwa mphamvu yamagetsi kumachitika ndi kuwonjezeka zolimbitsa thupi. Kuchita masewera olimbitsa thupi kwa aerobic kumathandiza thupi ndi thanzi. Uku ndikuyenda, kuthamanga, kusambira, kuvina, masewera a mpira, skating ice, kuyenda pansi.

Popewa zotsatira zosasangalatsa, mankhwalawa sichikwanira ndi zakumwa zoledzeretsa. Sichimayikidwa kwa ana, amayi panthawi yoyembekezera komanso mkaka wa m'mawere. Ndi matenda am'magazi a ziwalo, Orsoten amatha kwambiri kuvutitsa, amachititsa zovuta.

Anthu ambiri amawona kuyenera kwa zinthu zina zoonda kuchepa thupi malinga ndi ndemanga zaposachedwa pa intaneti.

Ogula enieni amagawana zomwe akukumana nazo komanso zotsatira za njirayi, amapatsa malangizo abwino ndi upangiri. Orsoten sichoncho. Nawa malingaliro ena kuchokera kwa anthu omwe amachepetsa thupi ndi mankhwalawa.

Ndemanga za 2018:

Alla wa zaka 32, mzinda wa Penza:

Ndimamwa mankhwalawa katatu patsiku, kutengera zomwe ndimadya. Kwa sabata loyamba ndidataya ma kilos 4. Izi ndi zotsatira zabwino, chifukwa m'mawa sindinadye chilichonse, ndipo kulemera kwake kudayima. Ndimayesetsa kuchepetsa zakudya.

Ndikuwona kuti m'mimba mwazolowera chakudya chochepa. Kuchepetsa thupi mopitilira apo, ndikhulupirira kuti kulemera kwambiri kumandisiya kwamuyaya. Zabwino zonse kwa anthu onse omwe amachepetsa kapena kuwonda!

Veronika wazaka 38, mzinda wa Rostov:

Kulemera kumayenda pang'onopang'ono koma ndithu. Kwa miyezi iwiri amataya 6 kg. Ndikukhulupirira kuti ndidzakwanitsa kulemera kwanganso mchaka chimodzi.

Makapisozi ndi abwino kumwa, ngati ndikudya zakudya zochepa komanso zamafuta ochepa, ndiye kudumpha phwando. Izi ndizololeka. Adatero dotolo. Zotsatira zake zoyipa, mapando otayirira, chikhumbo chabodza chofuna kunyoza, komanso pakamwa pouma ndizosokoneza. Mankhwalawa adapangira nthawi yayitali chithandizo, motero mtsogolomo ndizitenga.

Kristina wazaka 44, mzinda wa Kursk:

M'miyezi isanu ndi umodzi atatenga Orsoten, adataya 16 kg. Ndine wokhutira ndi izi, ndikupitiliza kumwa mopitilira. Ndikufuna kuti kulemera kusachulukire, ndikudalira zotsatira zokhazikika. Adaberekanso amayi ake pamapiritsi awa, ali ndi 35 kg wolemera mopitirira. Tsopano tikuchepetsa thupi limodzi.

Margarita wazaka 52, mzinda wa Moscow:

Sindigwiritsa ntchito mankhwala ochepetsa thupi nthawi yoyamba. Zotsatira zanga ndi opanda 20 kg m'miyezi 8. Orsoten ndi yosavuta kugwiritsa ntchito. Itha kuledzera mpaka zaka 2 popanda zosokoneza. Ndibwino kuti mukasowa kapsolo, mlingo wotsatira sukulira.

Ndikukhulupirira kuti kulemera komwe ndakwaniritsa sikukwera.

Orlistat - Chosakaniza chodziwika bwino m'mapiritsi ambiri azakudya komanso zoperekera zakudya.

Pamaziko a orlistat lipase inhibitor, Xenical, Listata, Xenistat, Orlimax ndi ena amadziwika kwa ambiri.

Kusiyanako kuli m'dziko lomwe limatulutsa mankhwalawo, mndandanda wazinthu zothandizira.

Gulu lina la analogu limaphatikizapo sibutramine, chinthu cha psychotropic chomwe chimatchinga pakatikati pa ubongo wa munthu.

Mankhwalawa ali ndi ntchito imodzi - kuti akwaniritse kuchepa thupi, ndipo mfundo zoyenera kuchita ndizosiyana. Orsoten amachotsa mafuta, amawalepheretsa kuti asaphwanyidwe komanso kumizidwa. Meridia, Reduxin, Goldline ndi ena amachepetsa kwambiri chilakolako chakufa chifukwa cha zochita za sibutramine.

Kusankha analog, Orsoten kapena Xenical - zomwe zili bwino, muyenera kuyang'ana pazotsatira zomwe zimapezeka pakuchepa thupi. Poyerekeza ndi kuwunikira, magwiridwe antchito a Orsoten ndiwokwera kwambiri, ndiye kuwonetsa pang'ono pazotsatira zoyipa.

Kwa chithunzi ndikukhala bwino, kuyenda maulendo ataliatali, kuchita masewera olimbitsa thupi, kuphunzitsa mphamvu ndikofunikira.

Kuti muchepetse kulemera kwakanthawi komanso kusunga zomwe mwapeza, malingaliro abwino, kuthandizira okondedwa ndikofunikira.

Moni. Dzina langa ndi Diana. Ndakhala ndikugwira ntchito ngati cosmetologist kwazaka zoposa 7. Ndikukhulupirira kuti ndine katswiri pantchito yanga ndipo ndikufuna kuthandiza alendo onse omwe amabwera pamalowa kuti athetse mavuto osiyanasiyana. Zida zonse za tsambalo zimasonkhanitsidwa ndikukonzedwa mosamala kuti athe kufotokoza zonse zofunika. Kufunsira kwa MANDATORY ndi akatswiri kumafunika musanagwiritse ntchito zomwe zafotokozedwa patsamba lino.

Zotsatira za pharmacological

Mapiritsi a zakudya a Orsoten amaletsa kuyamwa kwa mafuta m'matumbo. Mankhwala ali ndi yogwira ntchito orlistatzomwe zimalepheretsa chapamimba ndi pancreatic lipases. Chifukwa cha kutuluka kwa maubwenzi ogwirizana ndi chapamimba ndi kapamba kapamba orlistat simalola kuwonongeka kwa mafuta omwe amapezeka muzakudya. Ngati ma triglycerides sanaphwanyidwe, samatengedwa pakamwa. Amachotsedwa ndowe. Zotsatira zake, zopatsa mphamvu zochepa zimalowa m'thupi la munthu. Zotsatira zake, zonena zikuwonetsa kuti Orsoten amathandizira kuchepetsa thupi. Potere, kuyamwa kwazinthu zomwe sizigwira ntchito sikuchitika.

Pharmacodynamics ndi pharmacokinetics

Pa mlingo wa 60 mg katatu patsiku, mankhwalawa pafupifupi amaletsa kuyamwa kwa 25% ya mafuta ku chakudya.

Pambuyo maola 24 mpaka 48 mutatha kugwiritsa ntchito mankhwalawa, kuchuluka kwa mafuta m'matumbo amkati kumawonjezeka. Ngati mankhwalawo adathetsedwa, kuchuluka kwa mafuta m'matumbo amabwereranso pamiyeso yomweyo musanayambe kumwa, pambuyo pa maola 48-72.

Ngati mankhwalawa amatengedwa ndi munthu wamkulu wokhala ndi index yofunda kuposa 28 kg / m2, pa mlingo wa 60 mg katatu patsiku, mphamvu yake imachulukitsidwa pamene mankhwalawo akuphatikizidwa ndi zakudya zochepa zopatsa mphamvu. Kwenikweni, kulemera kwa thupi kumataika mwachangu m'miyezi isanu ndi umodzi yoyamba kumwa mankhwalawa.

Kuphatikiza pa kuchepetsa thupi, kumwa orlistat pa mlingo wa 60 mg katatu patsiku kumathandizira kuchepetsa zomwe zili cholesterol. Kuphatikiza apo, anthu omwe akuthandizidwa ndi mankhwalawa amachepetsa kukula kwamiyendo.

Malinga ndi kafukufuku, pali kuyamwa kochepa orlistat. Mankhwalawa akamagwiritsa ntchito magazi a m'magazi, orlistat yosasinthika imangokhala yokhayo, ndipo ndende yake imakhala yochepa kwambiri. Palibenso zizindikiro zakumvera.

Orlistat imamangiriza mapuloteni a plasma ndioposa 99%. Osachepera, amatha kulowa maselo ofiira amwazi.

Kupenda Amadziwika m'makoma a matumbo aang'ono ndi m'mimba. Pafupifupi 97% ya chinthucho imapukusidwa m'matumbo, kuphatikiza 83% ngati orlistat yosasinthika. Pafupifupi 2% yokha ya kuchuluka kwathunthu kwa impso. Kuchotsa kwathunthu kwa thupi kumachitika pakatha masiku 3-5.

Zotsatira zoyipa

Pogwiritsa ntchito makapisozi pafupipafupi, zotsatira zina zimayamba. Nthawi zambiri, awa ndimatumbo amtundu womwe umakhudzana ndi pharmacological ya mankhwala.

• Matumbo oyenda: mawonekedwe a kutulutsa kwamafuta kuchokera ku rectum, kusintha kwa mpweyakufunikira kwakanthawi kochepa kuti muchepetse, kupweteka pamimba, chopanda kumasuka, fecal kulepherapafupipafupi matumbo ambiri.
• Hematopoietic dongosolo: kuchuluka kwa MHO, kuchepa kwa ndende prothrombin.
• Chiwonetsero cha khungu: mawonekedwe chotupa champhongo.
• Mawonetseredwe amatsutsa: urticaria, zotupa, kuyabwa, bronchospasm, anaphylaxis, angioedema.
• Kutulutsa magazi pang'ono. chiwindi, diverticulitis, cholelithiasiskuchuluka kwa chiwindi michere.

Zotsatira zoyipa zikachitika, nthawi zonse muyenera kufunsa dokotala kuti mudziwe ngati mungapitirizebe kulandira chithandizo.

Malangizo ogwiritsira ntchito Orsoten (Njira ndi Mlingo)

Mankhwalawa amatengedwa pakamwa, pakudya kapena kwa ola limodzi mukamaliza kudya.

Malangizo pa Orsotin Slim amanenanso kuti wodwalayo ayenera kutsatira zakudya zochepa zopatsa mphamvu, pomwe pamakhala mafuta osaposa 30%. Chakudya chiyenera kugawidwa pawiri. Pamafunika nthawi yochuluka motani, momwe mungatulutsire makapisozi molondola kuti muchepetse thupi, ndipo adokotala ayenera kudziwa kuchuluka kwake.

Monga lamulo, achikulire amapatsidwa mankhwala ochepetsa mphamvu ya 120 mg katatu patsiku, ndiye kuti, akudya kapena akamaliza kudya. Ngati kunalibe chakudya, kapena chakudyacho kunalibe mafuta, simungatenge kapu.

Mlingo wapamwamba kwambiri wa Orsoten patsiku ndi makapisozi atatu. Ngati mankhwalawa atengedwa mu mlingo wopitilira 360 mg patsiku, mphamvu yake sikukula, koma chiwopsezo cha mavuto amabwera kwambiri.

Ngati kulemera kwamthupi la wodwalayo kumachepera ndi osakwana 5% m'milungu 12, chithandizo cha Orsotene ziyenera kusiyidwa.

Ndikulimbikitsidwa kutsatira chakudya ndikuchita fzolimbitsa thupi. Zakudya zoyenera komanso masewera ayenera kuchitidwa mutasiya kapu.

Kuchita

Ngati atengedwa nthawi yomweyo cyclosporin ndi orlistatkuchepa kwa ndende kumadziwika cyclosporine m'magazi amwazi. Zotsatira zake, ntchito zake za immunosuppressive zimachepa. Mankhwala munthawi yomweyo ndi mankhwalawa amatsutsana.

Phwando orlistat ndi warfarin kapena anticoagulants ena apakamwa amatsogolera pakusintha kwa mtengo wa MHO.

Chithandizo cha Orlistat chimabweretsa malabsorption mafuta mavitamini sungunuka.

Osagwiritsa ntchito nthawi yomweyo. orlistat ndi acarbose chifukwa cha kusowa kwa deta pamachitidwe awo.

Kulandila munthawi yomweyo amiodarone ndi orlistat, kuchuluka kwa plasma kwa amiodarone kuchepa. Gwiritsani ntchito mankhwalawa nthawi yomweyo pokhapokha akutsimikiziridwa ndi katswiri.

Palibe kuyanjana kwa Orsoten ndi Fenitoin, Atorvastatin, Amitriptyline, Fluoxetine, Phentermine, Sibutramine, Digoxin, Losartan, Mowakulera kwamlomo, komanso pravastatin, khwawa, mafupa.

Kuchepetsa thupi

Kuyankha funso, pali kusiyana kotani? Orsoten kuchokera Orsotin Slim, ziyenera kukumbukiridwa kaye kuti chinthu chogwiritsidwa ntchito m'magulu onse awiriwa ndi orlistat. Mlingo wokhawo umasiyana - 120 mg ya yogwira ntchito yomwe imagwiritsidwa ntchito mu Orsoten kapisozi, ndi 60 mg mu Orsoten Slim. Mukamasankha mankhwala ochepetsa thupi, kusiyanasiyana kuyenera kukumbukiridwa.

Pa mimba ndi mkaka wa m`mawere

Palibe zotsatira za maphunziro azachipatala omwe amachitika chifukwa cha mankhwala mimba komanso nthawi yoyamwitsa. Chifukwa chake, mankhwalawa sagwiritsidwa ntchito pochiza amayi apakati komanso amayi oyamwitsa.

Pamasamba osiyanasiyana ndi pamabowo pali ndemanga zambiri pa Orsoten kuti muchepetse kunenepa. Mwambiri, ndemanga za Orsotin Slim ndi Orsoten Plus awonetsetse phindu la mankhwalawa. Ndemanga za iwo omwe achepetsa thupi nthawi zambiri amaphatikiza kuchuluka kwa ma kilogalamu omwe mankhwalawa amathandizira munthu kuchepetsa thupi. Monga lamulo, zimadziwika kuti mapiritsi a zakudya a 120 mg amakulolani kuti muchepetse 5-7 kg pamwezi umodzi.

Kumbukirani kuti kuchepetsa thupi kuwunikira za Orsotene Slim ndi Orsotene akuwonetsa kuti zotsatira zabwino kwambiri za mankhwalawa zimawonedwa ndikuphatikiza zakudya zamagulu ochepa zama calorie. Pafupifupi malo onse ogwira ntchito ochepetsa thupi amakhala ndi zokambirana za momwe izi zimathandizira kuchepetsa thupi. Monga lamulo, zimadziwika kuti mankhwalawa amalimbikitsa zotsatira zoyipa ngati munthu samachepetsa kuchuluka kwa mafuta muzakudya.

Ndemanga za Madotolo zokhudza Orsoten ndizabwino kwambiri. Amavomereza mankhwalawa ngati analogue. Xenical, ndikuzindikira kuti kugwiritsa ntchito ndalama kuyenera kuchitidwa powonera kadyedwe komanso moyo wokangalika.

Mtengo wa Orsoten, koti mugule

Mtengo wapakati Orsotena chifukwa cha kuchepa thupi m'm ruble ndi 630 - 650 rubles. kwa makapu 21. Gulani ku Moscow Orsoten 120 mg (makapisozi 42) akhoza kukhala ma ruble 940-1000. Mtengo Orsotin Slim pafupifupi 1700-1800 ma ruble pa paketi (84 makapu). Kutsika mtengo pang'ono kumatanthawuza kuti mutha kugula mu pharmacy yapaintaneti ndi masheya ndi kuchotsera. Zambiri zomwe zili mu mankhwala a Orsoten, ziyenera kufotokozedwa panthawi yomwe ikugulitsidwa.

Mtengo ku Ukraine wa mankhwalawa (makapu 21) ndi pafupifupi 430-450 UAH. Ndizovuta kugula Orsoten ku Belarus. Monga lamulo, ku Minsk ndi mizinda ina ya dzikolo, muyenera kuyitanitsa chida chochepetsera kulemera kwama pharmacies opezeka pa intaneti. Momwemonso mutha kugula mankhwalawa ku Kazakhstan.

Pharmacokinetics

Orlistat imakhala ndi njira yochizira popanda kuyamwa mu kayendedwe kazinthu. Patatha maola 8 mutagwiritsidwa ntchito mkati, mankhwala omwe amapezeka m'madzi am'magazi ndi ochepera 5 ng / ml. Komabe, mayamwidwe ake ocheperako amatsimikiziridwa ndi kusapezeka kwa zizindikiro zokumbukira.

Mankhwalawa ndi 99% omangidwa ku albumin ndi lipoproteins, ocheperako amapezeka m'maselo ofiira a m'magazi. Zimapangidwa makamaka m'matumbo. Amapanga ma cellacologic osagwira metabolites M1 ndi M3. Pafupifupi 97% ya orlistat imachotsedwera limodzi ndi ndowe, 83% - yosasinthika. Pafupifupi maola 24-48 atayamba kumwa mankhwalawa, mafuta omwe amapezeka amawonjezeka. Nthawi yochotsa mankhwalawa kwathunthu ndi masiku 3-5.

Kuyanjana kwa mankhwala osokoneza bongo

Pogwiritsa ntchito munthawi yomweyo Orsoten wokhala ndi warfarin kapena anticoagulants, kusintha kwa magawo a hemostatic ndikotheka (kuchepa kwa prothrombin level, kuchuluka kwa INR).

Mukamamwa Orsoten osakanikirana ndi digoxin, fluoxetine, amitriptyline, phentermine, biguanides, fibrate, losartran, nifedipine, capopril, glibenclamide, sibutramine, ethanol ndi njira yolerera pakamwa, kugwiritsidwa ntchito kwa mankhwalawa sikuwonetsedwa.

Pogwiritsa ntchito nthawi yomweyo ndi cyclosporine, kuchuluka kwa omwe ali m'magazi kumachepa, chifukwa chake, kuyang'anira magawo a labotale kumafunika.

Mothandizidwa ndi Orsoten, zotsatira za hypolidemic ndi bioavailability wa kuchuluka kwa pravastatin (kuchuluka kwake mu plasma yamagazi kumawonjezeka ndi 30%).

Pogwiritsa ntchito munthawi yomweyo ndi amiodarone, kuchepa kwa ndende yake ndikotheka. Pankhaniyi, odwala amafunikira kuwunikira pafupipafupi ndi kuwunikira ECG.

Chifukwa cha kuthekera kwa mankhwalawa kusokoneza kuyamwa kwa mavitamini osungunuka a mafuta (A, D, E, K), amayenera kutengedwa asanagone, kapena maola awiri atatha kumwa Orsoten.

Ndi kuchepa kwa thupi chifukwa cha kagayidwe kachakudya, odwala matenda a shuga, mutatenga choletsa cha m'mimba lipases, tikulimbikitsidwa kuti muchepetse mulingo wa mankhwala a pakamwa a hypoglycemic.

Katundu wa zomwe zimagwira

Dongosolo losavomerezeka padziko lonse lapansi: orlistat (lat. Orlistat).

Dzina laling'ono: tetrahydrolipstatin.

Tchulani dzina la IUPAC lomasulira: 2S- (2-α (R *), 3-(-1- (3-hexyl-4-oxo-2-oxetanyl) -methyl dodecyl ether N-formyl-L-leucine.

Kuchuluka kwa maselo: 495.74.

Orlistat ndi yoyera ya makhiristo oyera, osungunuka mosavuta mu ma organic sol sol (methanol, ethanol) komanso osabowoka m'madzi. Thupi limadziwika ndi mkulu lipophilicity.

Zambiri zamankhwala

World Organisation of Gastroenterologists imayika orlistat ngati mankhwala othandiza kuchepetsa kunenepa kwambiri.

M'mayesero azachipatala, mankhwalawa adapangitsa kuchepa kwakukulu kwa kulemera kwa thupi mu 75% ya odwala odzipereka. Kwa milungu 12 ya chithandizo, odwala adatha kutaya mpaka 5% ya kulemera koyamba. Zotsatira zapamwamba (mpaka 10%) zimawonedwa mwa omwe amaphatikiza kugwiritsa ntchito mankhwalawa ndi zakudya zochepa zopatsa mphamvu komanso zolimbitsa thupi.

Pakati pa mayesowa, zotsatira zina zabwino za chithandizo cha mankhwala zidadziwika.

Makamaka, odwala omwe ali ndi matenda oopsa, kuchepa kwa kuthamanga kwa magazi kunawonedwa:

• systolic ("kumtunda") - pafupifupi 12.9 mm RT. Art.
• diastolic ("m'munsi") - mwa 7.6 mm RT. Art.

Onse odzipereka adawonetsa kusintha kwa metabolidi ya lipid. Patatha milungu 24 chiyambireni maphunziro, mankhwalawa amadzimadzi ambiri komanso otsika a lipoproteins (LDL) amatsika m'magazi.

Kafukufuku wambiri atsimikizira kuti orlistat imathandizira kupewa kapena kuchepetsa kufalikira kwa matenda a shuga II. Odwala omwe ali ndi vuto la kulolera glucose akamamwa, minyewa ya insulin imayamba kuyenda bwino. Odwala omwe ali ndi matenda ashuga okhazikika kale, chithandizo chokwanira chimalola kuchuluka kwa ma hypoglycemic othandizira.

Mkhalidwe wavomerezeka wa chinthu chogwira ntchito

Orlistat pakadali pano ndi okhawo omwe amavomerezedwa ndi chithandizo chamankhwala onenepa kwambiri. Komabe, chifukwa chochepa chogwiritsa ntchito mankhwalawa m'maiko osiyanasiyana, pamakhala mikangano yambiri yokhudza malamulo omwe amagawiridwa.

Orlistat poyamba anali akupezeka ndi mankhwala okha. Izi zikuchitika mpaka pano ku Canada.

Ku Australia ndi New Zealand mu 2003, mankhwalawo adasinthidwa kukhala m'gulu la OTC. Mu 2006, Australia Consumers Association idachita apilo ku State Agency for Drug Control ndi pempholi kuti abwezeretse orlistat momwe adalembedwera kale, ndipo adatsimikizira kuti kugulitsa kwaulere kungapangitse kuti mankhwalawo asagwiritsidwe ntchito mosagwirizana. Pempho lidakanidwa, koma Ofesiyi idalamula kuti aletse otsatsa orlistat.

Ku USA ndi ku maiko a European Union mu 2006-2009 idaloledwa kupatsa mankhwala ogulitsa makasitomala pamtengo wa 60 mg. Zokonzekera zomwe zili ndi 120 mg zitha kugulidwa pokhapokha ngati zikuwonetsa mawonekedwe apadera.

Kuphatikizika, mawonekedwe omasulira, ma CD

Orsoten amalandira kuchokera kwachilengedwe pogwiritsa ntchito chikhalidwe cha bakiteriya cha Streptomyces toxytricini. Choyimira chomaliza ndi chinthu chomaliza chokhala ndi orlistat ndi gawo lothandizira - microcellulose.

Mankhwala amapezeka mu mawonekedwe a makapisozi. Kapisozi imodzi imakhala ndi 225.6 mg ya mankhwala opangidwa ndi granular semi, omwe amafanana ndi 120 mg ya orlistat. Thupi la chivindikiro ndi kapisozi limapangidwa ndi hypromellose ndipo limakhala ndi mtundu woyera kapena wachikasu pang'ono.

Choikirachi chimayikidwa m'matumba a pulasitiki ndipo chimakhala m'makatoni 21, 42 kapena 84 ma PC.

Njira yamachitidwe

Pakuwongola kwa ngalande yokumba, Orsoten amalumikizana ndi ma gastric ndi pancreatic lipases, kutsekereza malo awo omwe amagwira ntchito. Chifukwa chake ma enzymes osakhazikika amasiya kutenga nawo mbali pakuwonongeka kwa mafuta. Popeza mamolekyu onse a lipid sangathe kulowetsedwa m'magazi, amawachotsa m'matumbo osasinthika. Kuchuluka kwa zopatsa mphamvu kuchokera ku chakudya kumachepetsedwa ndi pafupifupi 30%, zomwe zimapangitsa kuchepa kwa thupi. Kugwiritsidwa ntchito kwa Orsoten kumakhala kothandiza kwambiri kwa odwala omwe amakonda kutsata zakudya zamafuta kwambiri.

Kuphatikiza pa ntchito yayikulu, mankhwalawa:

• amachepetsa cholesterol "yoyipa" m'magazi,
• imalepheretsa kukula kwa matenda ashuga amtundu II,
• amachepetsa kuthamanga kwa magazi.

Kugwiritsidwa ntchito kwa nthawi yayitali kwa Orsoten, mawonekedwe a Reflex mu odwala, omwe amakhala kuti kuphwanya zakudya zamafuta amakhudzana kwambiri ndi zotsatirapo zoyipa za mankhwalawa (kutsegula m'mimba ndi chimbudzi). Zotsatira zake, ngakhale osakhala ndi chidwi chochepa chochepetsa thupi, wodwalayo mwadzidzidzi amayamba kutsatira zakudya zochepa zopatsa mphamvu.

Ndi chithandizo chazitali ndi Orsoten, kulemera kwa thupi kumachepa pang'onopang'ono, molingana ndi zakudya zopatsa thanzi. Pafupifupi, m'miyezi itatu yamankhwala, odwala amataya mapaundi owonjezera 5 mpaka 8.

Kutetemera ndi chimbudzi

Mankhwalawa amagwira ntchito m'mimba, soti sangatengeke m'magazi. Maola 8 mutatenga Orsoten, kuchuluka kwake m'magazi kuli pafupifupi 6 ng / ml, komwe kumatsimikizira kuyamwa kochepa kwa mankhwalawa.

Gawo lalikulu la mankhwalawa limachotsedwamo ndowe, ndipo 83% ya mlingo womwe umamwa umasinthidwa. Pakatikati pang'onopang'ono mumgawo wamatumbo mumakhala zinthu zopanda ntchito. Ma metabolabol amamuchotsa impso ndi bile.

Nthawi ya kuchotsa kwathunthu mankhwala kuchokera mthupi kuyambira 3 mpaka 5 masiku.

Orsoten analimbikitsa:

• pa chithandizo cha kunenepa kwambiri kwanthawi yayitali (wokhala ndi cholembera chachikulu cha makilogalamu 30 / m²),
• kuthana ndi kunenepa kwambiri (wokhala ndi BMI yosachepera 27 kg / m²).

Mankhwalawa amatha kugwiritsidwa ntchito ndi odwala omwe ali pachiwopsezo chachikulu chokhala ndi matenda amtima komanso matenda a shuga. Ngati ndi kotheka, ndizovomerezeka kuchita mankhwala osakanikirana ndi othandizira a hypoglycemic.

Mimba komanso kuyamwa

Palibe zambiri zachipatala pazokhudzana ndi orlistat pa mwana wosabadwayo, chifukwa chake, kutenga Orsoten panthawi yoyembekezera sikulimbikitsidwa.

Mankhwala mukamayamwitsa amaonanso osafunika. Mankhwala amalepheretsa mayamwidwe osungunuka a mafuta, kuchepa kwake komwe kungasokoneze kukula kwa mwana.

Mlingo ndi makonzedwe

Kuwonetsedwa kwa zotsatira za orlistat kumafunika kukhalapo kwa lipases m'mimba. Popeza kupanga ma enzyme kumachitika pokhapokha chakudya, Orsoten amayenera kudyedwa ndi chakudya kapena pasanathe ola limodzi itatha.

Malangizo othandizira: 1 kapisozi katatu pa tsiku. Mankhwala ayenera kutsukidwa ndi madzi ochepa. Ngati chakudyacho chilibe mafuta kapena wodwalayo amalumpha chakudya, ndiye kuti Orsoten sangatengedwe. Kutalika kokwanira kovomerezeka kwamankhwala ndi zaka ziwiri.

Kutenga mankhwalawa mu Mlingo wopitilira muyeso sikuti kumawonjezera zotsatira zake.

Zotsatira zoyipa

Zotsatira zoyipa zomwe Orsoten amakonda kuchita zimaphatikizapo:

• mafuta chopondapo
• mafuta ochulukirapo kuchokera ku rectum,
• ukufalikira
• pafupipafupi kukakamira,
• kupweteka kwam'mimba
• kusamva bwino m'matumbo,
• kuchuluka kwa chopondapo
• fecal kulephera
• kuwonongeka kwa mano ndi mano,
• maonekedwe a nkhawa,
• kufooka
• matenda a chapamwamba kupuma ndi kwamikodzo thirakiti.

Zosowa kwambiri mwa odwala:

• thupi lawo siligwirizana (mawonekedwe a zotupa pakhungu, kuyabwa, bronchospasm kapena anaphylaxis),
• matenda a ndulu
• chiwindi
• kuchuluka kwa hepatic transaminases ndi zamchere phosphatase,
• diverticulitis
• chotupa champhongo.

Kukula kwa zovuta zakumwa kuchokera m'matumbo am'mimba zimatengera mafuta omwe amapezeka muzakudya, kotero ndikofunikira kuphatikiza mankhwalawa ndi zakudya zochepa zopatsa mphamvu.

Nthawi zambiri, zotsatira zoyipa zimawoneka m'miyezi itatu yoyambirira ya chithandizo. Mankhwala akamapitiliza, zizindikiro zosasangalatsa zimachepa.

Gulu la Nosological (ICD-10)

Kufotokozera za mtundu wa kipimo

Makapisozi a Hypromellose.

Wotayika ndi kapisozi thupi kuchokera oyera mpaka oyera ndi tint chikasu.

Zolemba za Capsule - ma Microganu kapena kusakaniza kwa ufa ndi ma micogranules oyera kapena pafupifupi oyera. Kupezeka kwa ma coslomerates okhathamira amaloledwa, komwe kumatha kugonjetsedwa mosavuta.

Zisonyezero za mankhwala Orsoten ®

chithandizo chamanthawi yayitali kwa odwala omwe ali ndi kunenepa kwambiri (BMI ≥30 kg / m 2) kapena odwala onenepa kwambiri (BMI ≥28 kg / m 2) omwe ali ndi chiopsezo chokhudzana ndi kunenepa kwambiri, chophatikizidwa ndi kadyedwe koyenera ka hypocaloric,

kuphatikiza mankhwala a hypoglycemic (metformin, sulfonylurea zotumphukira ndi / kapena insulin) ndi / kapena zakudya zapamwamba za hypocaloric mwa odwala omwe ali ndi matenda a shuga 2 kapena onenepa kwambiri.

Mimba komanso kuyamwa

Mu maphunziro a poizoni wazinyama, palibe teratogenic ndi embryotoxic zotsatira za orlistat zomwe zimawonedwa. Pokhapokha ngati teratogenic zotsatira mu nyama, zofanana mu anthu sayenera kuyembekezera. Komabe, chifukwa cha kuchepa kwa deta yamankhwala, Orsoten ® sayenera kulembedwa kwa amayi apakati.

Sizikudziwika ngati orlistat imadutsa mkaka wa m'mawere, kotero kugwiritsa ntchito nthawi yoyamwitsa kumatsutsana.

Wopanga

LLC KRKA-RUS. 143500, Russia, Moscow Region, Istra, ul. Moscow, 50.

Tele. ((495) 994-70-70, fakisi: (495) 994-70-78.

Dzina ndi adilesi ya yemwe ali ndi satifiketi yolembetsa: LLC "KRKA-RUS", Russia.

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Tele. ((495) 981-10-95, fakisi: (495) 981-10-91.