Mafuta A Ofloxacin

m'matumba kapena m'mbale ya ma PC 10., mumapaketi a kakhadi 1 kapu kapena mtsuko.

m'mabotolo amdima amdima 100 ml, mumapaketi a makatoni 1.

mu machubu azitsulo a 3 kapena 5 g, mu paketi yamatoni 1 chubu.

Mankhwala

Yogwira motsutsana ndi tizilombo tating'onoting'ono tokhala ndi beta-lactamases komanso mycobacteria yomwe ikukula mofulumira. Zovuta: Staphylococcus aureus, Staphylococcus epermidis, Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Citrobacter, Klebsiella spp., (Kuphatikiza Klebsiella pneumoniae), Enterobacter spp. (kuphatikiza Enterobacter cloacae), Hafnia, Proteus spp. (kuphatikiza Proteus mirabilis, Proteus vulgaris - indole zabwino komanso indole hasi), Salmonella spp., Shigella spp. (kuphatikiza Shigella sonnei), Yersinia enterocolitica, Campylobacter jejuni, Aeromonas hydrophila, Plesiomonas aeruginosa, Vibrio cholerae, Vibrio parahaemolyticus, Haemophilus influenzae, Chlamydia spp. (kuphatikiza Chlamydia trachomatis), Legionella spp., Serratia spp., Providencia spp., Haemophilus ducreyi, Bordetella parapertussis, Bordetella pertussis, Moraxella catarrhalis, Propionibacterium acnes, Staphylococcus spp, Brucella.

Osiyana kudziwa mankhwala adzalandira: Enterococcus faecalis, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus viridans, Serratia marcescens, Pseudomonas aeruginosa, Acinetobacter, Mycoplasma hominis, Mycoplasma pneumoniae, Mycobacterium TB, Mycobacterium fortuitum, Ureaplasma urealyticum, Clostridium perfringens, Corynebacterium spp, Helicobacter pylori. , Listeria monocytogene, Gardnerella vaginalis.

Mwambiri, osaganizira: Nocardia asteroides, bacteria wa anaerobic (mwachitsanzo. Bacteroides spp., Peptococcus spp., Peptostreptococcus spp., Eubacterium spp., Fusobacterium spp., ClostridiumGHile). Zosagwira Treponema pallidum.

Pharmacokinetics

Pambuyo pakumwa pakamwa, imathamanga ndipo imakhudzidwa kwathunthu. Bioavailability - woposa 96%, womanga kumapuloteni a plasma - 25%. T_max ndi maola 1-2, C_max mutamwa mlingo wa 100, 300, 600 mg ndi 1, 3.4 ndi 6.9 mg / L. Pambuyo pa mlingo umodzi wa 200 kapena 400 mg, ndi 2.5 μg / ml ndi 5 μg / ml, motsatana.

Voliyumu yomwe ikuwoneka ndi magawo 100. Imalowa mu minofu, ziwalo ndi mafayilo amthupi: kulowa m'maselo (ma cell oyera am'magazi, ma alveolar macrophages), khungu, minofu yofewa, mafupa, ziwalo zam'mimba ndi ziwalo, kupuma kwamkodzo, mkodzo, malovu, bile, katulutsidwe ka prostate, kudutsa BBB, chotchinga, chomwe chimapukusidwa mkaka wa m'mawere. Imalowa m'madzi amadzimadzi amadzimadzi otupa komanso osapweteka (14-60%).

Zimapangidwa mu chiwindi (pafupifupi 5%) ndikupanga kwa N-oxide ofloxacin ndi dimethylofloxacin. T_1/2 sizitengera mlingo ndipo umakwanitsa maola 4.5-7. Amatulutsidwa ndi impso 75-90% (osasinthika), pafupifupi 4% - ndi bile. Chilolezo chowonjezera - zosakwana 20%.

Pambuyo pa mlingo umodzi wa 200 mg mumkodzo, umapezeka mkati mwa maola 20 mpaka 24. Ndi kuperewera kwa impso / hepatic, chimbudzi chitha kuchepa. Sichikupanga.

Zisonyezero Ofloxacin

Matenda a kupuma thirakiti (bronchitis, chibayo), ENT ziwalo (sinusitis, pharyngitis, otitis media, laryngitis), khungu, minofu yofewa, mafupa, mafupa, matenda opatsirana ndi otupa a m'mimba ndi thirakiti la biliary (kupatula mabakiteriya am'mimba), impso ( pyelonephritis), kwamikodzo thirakiti (cystitis, urethritis), ziwalo zamkati ndi kumaliseche (endometritis, salpingitis, oophoritis, cervicitis, parametritis, prostatitis, colpitis, orchitis, epididymitis), gonorrhea, chlamydia, septicemia ( , meningitis, kupewa matenda ol ndi udindo chakhungu m'thupi (kuphatikizapo neutropenia a), bakiteriya corneal zilonda, conjunctivitis, blepharitis, meybomit (balere), dacryocystitis, keratitis, matenda chlamydial diso.

Kuphatikizika ndi katundu

Mafuta a Ofloxacin ndi mankhwala ochokera pagulu la fluoroquinolones lomwe lili ndi antibacterial.

Amapezeka m'matumba a aluminiyumu a 3 kapena 5. Phukusili lili ndi malangizo ogwiritsira ntchito. Chosakaniza chophatikizacho ndi chaloxacin. Zowonjezera:

• methyl parahydroxybenzoate,
• mafuta odzola,
• propyl parahydroxybenzoate.

Mukamagwiritsa ntchito mankhwalawa, gawo lomwe limagwiritsidwa ntchito ndi mankhwalawa limakhudza mtundu wa DNA wa ligilli, womwe umatsimikizira kukhazikika kwa DNA ya tizilombo toyambitsa matenda. Zotsatira zake, mabakiteriya amayamba kufa. Ofloxacin amagwira ntchito molingana ndi mitundu iyi:

Gawo lalikulu la mankhwalawa limawononga salmonella.

• khalimotz,
• Esherichia coli,
• Providencia spp.,
• shigella
• Haemophilus fuluwenza,
• Salmonella
• Neisseria meningitidis,
• chlamydia
• streptococci,
• Propionibacterium acnes,
• Pseudomonas aeruginosa,
• Morganella morganii,
• Pseudomonas aeruginosa,
• brucella
• Klebsiella,
• Mycoplasma et al.

Ndi makonzedwe akunja, chigawo chogwira ntchito chimapezeka mu conjunctiva, iris, cornea, sclera, minofu, ndi chipinda chamkati. Pogwiritsa ntchito mobwerezabwereza, kugwiritsidwa ntchito kwa chinthu chachikulu mu vitreous kumatheka. Tizilombo tating'onoting'ono, timankhwala topezeka ndimankhwala amawonedwa kuposa chinyezi cha maso. Pazitali kwambiri ya mankhwalawa m'magawo a sclera ndi conjunctiva amachitika mkati mwa mphindi 5. mutagona mankhwalawo, ndipo anthu omwe amagwira ntchitoyo amayamba kuseka pambuyo pa ola limodzi. Kenako kukhazikika kwa mankhwalawa kumachepetsedwa.

Mafuta a Ofloxacin amaperekedwa kuti azitsatira zotsatirazi zowona:

• matenda a bakiteriya am'maso - blepharitis, keratitis, conjunctivitis, etc.
• chlamydial njira matenda a ziwalo.
• dacryocystitis
• zilonda zam'mimba,
• barele
• kupewa mavuto pambuyo ophthalmic opaleshoni.

Malangizo ogwiritsira ntchito

Musanalowe mankhwalawa, mufunikira upangiri wa oculist. Pa matenda onse a ophthalmic, kupatulapo matenda amtundu wa chlamydial, mankhwalawa amayenera kuyikidwa pamalo am'munsi mwa conjunctival sac ndi Mzere wa 1 masentimita mpaka 3 katatu patsiku, ndi matenda a chlamydial - 5-6 patsiku. Mankhwalawa amaperekedwa mwachindunji kuchokera ku chubu. Kutalika kwa chithandizo mpaka milungu iwiri. Ndi matenda a chlamydial a ziwalo za masomphenyawo, nthawi ya mankhwala ndi masiku 28-35.

Mankhwala amayenera kugwiritsidwa ntchito atasunthira kumbuyo kwa eyelid.

Njira yothira mafuta:

1. Sunthani m'munsi chikope.
2. Yambitsani mankhwala a 10 mm m'dera la conjunctival sac.
3. Tsekani diso ndikusunthira mbali zosiyanasiyana kuti mankhwalawo agawirenso.

Contraindication

Mafuta a Ofloxacin sagwiritsidwa ntchito zotsatirazi:

• Hypersensitivity pamagawo a mankhwala,
• aakulu conjunctivitis osachokera mabakiteriya,
• mimba ndi mkaka wa m`mawere
• zaka mpaka 15.

Zotsatira zoyipa

Mukamagwiritsa ntchito Ofloxacin, izi zimachitika motere;

Nthawi zina pambuyo pa mankhwalawa, conjunctiva imatha kusinthika kwakanthawi.

• kusapeza bwino
• Hyperemia,
• lacure
• kuyabwa
• kumverera koyaka
• edjunctival edema,
• Diso louma
• Photophobia
• mawonetseredwe amomwe thupi limachita.

Kugwirizana

Kugwiritsa ntchito limodzi ndi NSAIDs, nitroimidazole ndi methylxanthine kumawonjezera mwayi wa zochitika za neurotoxic komanso zimachitika.

Mukamagwiritsa ntchito mankhwalawa limodzi ndi mankhwala ena, zotsatirazi ziyenera kuganiziridwa:

• Kugwiritsa ntchito nthawi imodzi ndi mankhwala omwe amaphatikiza magnesium, iron, aluminium kapena zinc, amathandizira kuti muchepetse kuyamwa kwa ofloxacin. Izi zimagwiranso ntchito ma antacid ndi sucralfate.
• Mukamagwiritsa ntchito limodzi ndi ma anticoagulants omwe ali ndi zotsatira zosadziwika, kugwira ntchito kwawo kumawonjezeka, chifukwa chake muyenera kuwongolera pulogalamu yoyipa.
• Mankhwalawa sakukhudzana ndi mankhwala ena am'deralo a ophthalmic. Komabe, pogwiritsa ntchito limodzi, kupuma pakati pa kugwiritsa ntchito mankhwala osachepera mphindi 15 ndikofunikira. Ofloxacin, pamenepa, ayenera kuyikidwa pansi.

Bongo

Malinga ndi kufotokozeredwa, palibe chidziwitso cha kuchuluka kwa kuchuluka. Ngati mwamwa mwangozi mankhwala mkati, mungagwiritse zotsatirazi:

• kusokonezeka kwa chikumbumtima
• chizungulire
• kugona kwambiri
• kusanza
• chisokonezo,
• ulesi.

Zikatero, muyenera:

Mitu ya mankhwalawa

Ofloxacin ali ndimalo olowa m'malo monga Azitsin, Phloxal, Vero-Ofloxacin, Tetracycline, Oflomelid, Vilprafen, Zitroks, Levomycetin. Zofanizira zonsezi zimakhala ndi antibacterial ndipo zimathandizira kuti matenda a maso athetsedwe. Musanalowe m'malo mwa "Ofloxacin" ndi mankhwala ena aliwonse, muyenera kufunsa katswiri wa ophthalmologist. Dokotala adzakuthandizani kusankha analogue oyenera.

Zizindikiro zogwiritsidwa ntchito

Popeza antibacterial katundu wa mankhwalawa, amapatsidwa mankhwala ochizira matenda a impso, kwamikodzo thirakiti, matenda a pakhungu. Mu matenda amphuno a chlamydia, chinzonono. Chifukwa chake, mankhwalawa ndiwotchuka kwambiri.

Mu ophthalmology, amatchulidwa pamaso pa zotumphukira ndi matenda:

• Diso la chlamydia
• zotupa za cornea
• blepharitis
• barele
• kuwonongeka kwa bakiteriya
• keratitis
• bakiteriya conjunctivitis.

Itha kugwiritsidwa ntchito kuteteza zovuta mu nthawi ya postoperative. Makamaka ndi kuwonongeka kwa ma corneal.

Madokotala amalimbikitsa mankhwalawa nthawi zambiri. Kuchita kwake komanso mtengo wotsika zimapangitsa Ofloxacin kupezeka kwa wodwala aliyense. M'mafakisi a ku Russia, mtengo wa mafuta ambiri ndi ma ruble 35-65.

Zomwe zimagwira mafuta awa ndi aloxacin. Pangani mankhwala osokoneza bongo osiyanasiyana - 3 ndi 5 mg.

Musanagwiritse ntchito, muyenera kusamala mosamala kapangidwe ka mankhwalawo komanso kupatula kukhalapo kwa hypersensitivity kapena kusalolera kwa munthu.

Malangizo apadera

Ndikofunikira kudziwa kuti sikofunikira kwenikweni kugwiritsa ntchito mankhwalawa ndi mowa nthawi yomweyo. Kuyanjana kotereku kungapangitse kuti pakhale zovuta. Zochita za mankhwala sizichedwa kuchepetsedwa nthawi zotere. Panthawi yamankhwala, magalasi ochezera ayenera kuchotsedwa. Ngati ndi kotheka, amaloledwa ndi magalasi.

Nthawi zina munthawi yamankhwala, odwala amakhala ndi chidwi chowala. Nthawi yomweyo, kusiya mankhwala sikofunikira. Wodwalayo akulangizidwa kuti azigwiritsa ntchito magalasi mpaka kumapeto kwa mankhwala.

Pafupifupi odwala onse, atayika mafuta, kuchepa kwamawonekedwe kumawonedwa. Izi zimakhalapo kwakanthawi ndipo zimadutsa mphindi 15. Popeza izi, pambuyo pa njirayi ayenera kupewa kuyendetsa magalimoto. Mutha kubwereranso kuntchito ndikuyendetsa galimoto mukamabwezeretsa masomphenya.

Kuchita ndi mankhwala ena

Munthawi yogwiritsira ntchito Oflaxacin, zotsatira zake zimachepa pomwe amagwiritsidwa ntchito ndi mankhwala omwe ali ndi chitsulo, magnesium, zinc, ndi aluminium. Kutsika kwa zotsatira kumawonedwanso pakukhudzana ndi maantacid ndi sucralfate.

Mafuta amatha kuwonjezera mphamvu ya ma anticoagulants. Ndi kulumikizana uku, ndikofunikira kuwongolera momwe magazi akupangidwira. Ntchito zolimbitsa thupi ndi zotsatira za neurotoxic zimatha kukula mukamayanjana ndi methylxanthines ndi nitroimidazoles. Zotsatira zoterezi zimatha kuchitika pogwiritsa ntchito mankhwala omwe si a antiidal.

Kuchita ndi magulu ena a ophthalmic akukonzekera sikuwonetsedwa. Ndi kugwiritsa ntchito mankhwala osiyanasiyana munthawi yomweyo, mphindi 15 ziyenera kuonedwa. Mafuta amayikidwa pambuyo pokhazikitsa madontho.

Zotsatira zoyipa

Mankhwalawa ndi otetezeka ndipo kawirikawiri samayambitsa zovuta. Kwenikweni, zimawonekera monga mawonekedwe:

• kuyaka
• kuyabwa
• kudziwa kuwala
• kutupa
• redness
• kwambiri lacrimation kapena kusintha zochita mu mawonekedwe a youma.

Pankhani yovuta, ndikofunikira kusiya chithandizo ndikuyang'ana kwa dokotala. Kuti muchepetse zotsatira zosafunikira, ndikokwanira kusiya mankhwalawo.

Pomaliza

Mafuta a Ofloxacin ndi mankhwala ochizira matenda am'maso omwe amayamba chifukwa cha bakiteriya komanso tizilombo tina tomwe timayambitsa matenda. Mphamvu yakumaloko yamankhwala imakupatsani mwayi wothandizira kwambiri pakuwunika matenda ndikubwezeretsa maselo a pakhungu ndi mucous nembanemba.

Njira yogwiritsira ntchito ndi malangizo a mafuta a Ofloxacin:

1. Sambani m'manja musanayambe kugwiritsa ntchito.
2. Kokani eyelid ya m'munsi ndikufinya mankhwalawo kuchokera ku chubu kupita ku conjunctival sac.
3. Pakangogwiritsidwa ntchito kamodzi, gwiritsani ntchito mzere wamafuta 1 cm.
4. Tsekani eyelid ndikusunthira diso lanu mbali zosiyanasiyana kuti mafuta azikhala bwino.
5. Kutalika kwa mankhwalawa ndi mafuta a Ofloxacin ndi masabata awiri. Matenda ena amafunikira kuwonjezera njira ya achire.

Mafuta a Ofloxacin, malangizo ogwiritsira ntchito

Kwa eyelid ya m'munsi, 1-1,5 cm yamafuta imayikidwa katatu patsiku. Kutengera kupezeka chlamydial diso zotupa - 5 pa tsiku. Chithandizo ikuchitika zosaposa milungu iwiri. Pogwiritsa ntchito nthawi yomweyo mankhwala angapo, mafuta omwe amagwiritsidwa ntchito omaliza.

Mapiritsi amatengedwa pakamwa, kwathunthu, musanadye kapena pakudya. Mlingo amasankhidwa malinga ndi kukula kwa matenda, chiwindi ndi impso. Mlingo wamba ndi 200-600 mg patsiku, womwe umagawidwa pawiri. Odwala kwambiri komanso onenepa kwambiri, tsiku lililonse mlingo umawonjezeka mpaka 800 mg. At chinzonono 400 mg ndi zotchulidwa muyeso umodzi, kamodzi, m'mawa.

Ana amasankhidwa pazifukwa zaumoyo, ngati palibe choloweza mmalo ndi njira zina. Mlingo watsiku ndi tsiku ndi 7.5 mg wa pa kilogalamu iliyonse ya thupi.

Odwala ndi mkhutu aimpso ntchito dosed. Odwala omwe ali ndi vuto lalikulu la chiwindi, mlingo wa tsiku ndi tsiku sayenera kupitirira 400 mg. Kutalika kwa mankhwalawa kumatsimikizika ndi kuopsa kwa matendawa. Chithandizo chimapitilirabe masiku ena atatu kuchokera pakumatha kutentha kapena pambuyo pa mayeso a labotale kufooketsa tizilombo. Nthawi zambiri, nthawi ya maphunzirowa ndi masiku 7-10, nsomba Masiku 7 odwala matenda a kwamikodzo mpaka masiku 5. Kuchiza sikuyenera kupitirira miyezi iwiri. Mankhwalawa matenda ena, Ofloxacin amapatsidwa koyamba mkati mwa 2 kawiri pa tsiku ndikusinthira pakamwa.

Dontho lokhazikika ofloxacin yoperekedwa pansi pa dzina Danzil, Phloxal, Uniflox. Onani malangizo ogwiritsira ntchito mankhwalawa.

Kuwonetsedwa chizungulire, kubweza, kugona, chisokonezo, chisokonezo, spasms, kusanza. Chithandizo chimakhala ndi chapamimba cham'mimba, kukakamiza diuresis ndi chizindikiro. Ndi yogwira mtima matenda Diazepam.

Mukapangana sucralfataMaantacid okhala ndi zokonzekera zomwe zimakhala ndi aluminiyamu, zinc, magnesium kapena chitsulo, kuchepetsedwa kwa mayamwa ofloxacin. Pali kuwonjezeka kwa mphamvu ya mankhwala osagwirizana mukamamwa mankhwala. Kuyendetsa dongosolo la coagulation kumafunikira.

Chiwopsezo cha zotsatira za neurotoxic ndi ntchito zopweteka zimawonjezeka ndi makonzedwe amodzi a NSAIDs, zotumphukira. nitroimidazole ndi methylxanthines.

Mukamagwiritsa ntchito Theofylline chilolezo chake chimachepa ndipo kuwonongedwa kwa theka la moyo kumakulanso.

Kugwiritsira ntchito nthawi yomweyo kwa othandizira a hypoglycemic kungayambitse mikhalidwe ya hypo- kapena hyperglycemic.

Mukamagwiritsa ntchito Cyclosporine pali kuwonjezeka kwa kuchuluka kwake m'magazi ndi theka la moyo.

Khalid, Furosemide, Cimetidine ndi Methotrexate Kuchepetsa katulutsidwe katulutsidwe kogwira ntchito, kamene kamaphatikizira kuwonjezereka kwa ndende yake m'madzi a m'magazi.

Mwinanso kuchepa kwambiri kwa kuthamanga kwa magazi mukamagwiritsa ntchito barbiturates ndi antihypertensive mankhwala.

Mukamagwiritsa ntchito glucocorticosteroids pamakhala chiwopsezo cha kupasuka kwa tendon.

Kutalika kwa nthawi ya QT ndikugwiritsa ntchito antipsychotic, antiarrhythmic mankhwala, ma tridclic antidepressants, macrolides, imidazole. astemizole, terfenadine, ebastina.

Kugwiritsa ntchito kaboni wa anhydrase inhibitors, sodium bicarbonate ndi ma citrate, omwe amachititsa kuti mkodzo uthandizidwe, umawonjezera chiopsezo cha crystalluria ndi nephrotoxicity.

Amamasulidwa pa mankhwala.

Kutentha kosungira mpaka 25 ° C.

Mowa sugwirizana ndi mankhwalawa. Pa mankhwala, mowa saloledwa.

Kukonzekera: Zanocin, Zoflox, Ofloxin.

Mayankho a kulowetsedwa: Nthawi zambiri, Tarivid, Ofloxabol.

Anloxacin analog, yomwe imapezeka ngati mafuta amaso - PhloxalMawonekedwe amaso / khutu - Danzil, Uniflox.

Fluoroquinolones khalani ndi mwayi wothandizira pakati pa antimicrobial othandizira ndipo amawerengedwa ngati njira ina yothandizira maantibayotiki othandizira odwala matenda oopsa. Pakadali pano, nthumwi yoyimira m'badwo wachiwiri sunatayebe patsogolo -ofloxacin.

Ubwino wa mankhwalawa kuposa mitundu ina ya fluoroquinolones ndi bioavailability wambiri, komanso pang'onopang'ono komanso kawirikawiri zomwe sizikuvuta kukana kwa tizilombo.

Popeza ntchito yayikulu yolimbana ndi matenda opatsirana opatsirana pogonana, mankhwalawa amagwiritsidwa ntchito kwambiri mu dermatovenerology pochiza matenda opatsirana pogonana: urogenital chlamydia, chinzonono, gonorrhea-chlamydial, mycoplasma ndi ureaplasma matenda. Kutha kwa Chlamydia kumawonedwa pazochitika za 81-100% ndipo amadziwika kuti ndiwothandiza kwambiri kuposa fluoroquinolones onse. Izi zikuchitiranso umboni ndi ndemanga ya Ofloxacin:

• "... Ndidamwa mankhwalawa, ndidalandira chithandizo cha mycoplasma ndi ureaplasma. Bwino, "
• "... Zinandithandiza, ndimamwa ndi cystitis, palibe mavuto. Mankhwalawa ndiokwera mtengo komanso ogwira ntchito. "

Kutulutsa kokwanira kokwanira, kulowa kolowera mkati mwa ziwalo zamkati, kwamikodzo dongosolo, kutsekeka kwa chithokomiro cha prostate, kusungidwa kwazitali kwa nthawi yayitali pakuwunikira kumapangitsa kugwiritsidwa ntchito kwake mu matenda a urological and gynecological. Chifukwa chake, pali ndemanga kuti kumwa mankhwalawa kwa masiku atatu kwawonetsa kukwaniritsa kwambiri cystitis mwa azimayi. Adalembera prophylactic zolinga pambuyo diathermocoagulation wa khomo lachiberekero kukokoloka pambuyo makonzedwe intrauterine kulerapambuyo kuchotsa mimbaikugwirira ntchito moyenera prostatitis, khungu.

Pokhala osagwiritsa ntchito maantibayotiki, sizikhudza nyini ndi m'mimba, sizimayambitsa dysbiosis. Malinga ndi odwala, mankhwalawa salekerera bwino. Nthawi zambiri, zoyipa zam'mimba zimadziwika, nthawi zambiri - kuchokera pakatikati wamanjenje komanso khungu lanu siligwirizana, kawirikawiri - kusintha kwakanthawi kwamayesero a chiwindi. Mankhwala alibe hepato-, nephro- ndi ototoxic zotsatira.

• "... panali nseru, m'mimba mwanga mudali tulo, kunalibe chakudya,"
• "... Ndinadwala kwambiri, sindingathe kudya chilichonse, koma ndamaliza maphunziro,"
• "... Atagona tulo. Ndimakayikira kuti mankhwalawa, chifukwa ndimagona bwino, "
• "... anaponyedwa pamoto ndi thukuta lozizira, panali mantha."

Kwa odwala ambiri omwe ali ndi conjunctivitis, blepharitis ndi keratitis Diso lotumizidwa limatsika ndi yogwira ntchito ofloxacin (Uniflox, Phloxal, Danzil), ndemanga zake zabwino. Odwala anali kuwagwiritsa ntchito 4-5 pa tsiku blepharitis ndi conjunctivitis ndipo adawona kusintha kwakukulu mkati mwa masiku awiri. Chifukwa cha kukhudzidwa kwambiri kwa zinthu zomwe zikugwira, madontho amatha kugwiritsidwanso ntchito pochotsa zilonda zakuya - uveitis, scleritis ndi iridocyclitis.

Mutha kugula mankhwalawo ku pharmacy iliyonse. Mtengo wake umatengera wopanga. Mtengo wa Ofloxacin pamapiritsi a 200 mg opangidwa ku Russia (Ozone, Makiz Pharma, OJSC Synthesis) amachokera ku ruble 26. mpaka 30 rub. Mapiritsi 10, ndipo mtengo wamapiritsi ndi 400 mg No. 10 kuchokera ku 53 mpaka 59 ma ruble. Teloxacin Teva, wopangidwa kokha mu mapiritsi a 200 mg, amawononga ndalama zambiri - 163-180 rubles. Mafuta odzola ndi maso (Kurgan Synthesis OJSC) amalipira 38 mpaka 64 rubles. m'magulu osiyanasiyana.

Mtengo wa Ofloxacin ku Ukraine ndi 11-14 UAH. (mapiritsi), 35-40 UAH. (yankho la kulowetsedwa).

Ofloxacin njira 2 mg / ml 100 ml mu yankho la sodium kolorayidi 0,9% kaphatikizidwe ka OJSC

Levofloxacin mapiritsi 500 mg 5 ma PC Vertex

Waprofloxacin mapiritsi 250 mg 10 ma PC. Ozone LLC

Levofloxacin mapiritsi 500 mg 10 ma PC Vertex

Mapiritsi a Ofloxacin-Teva 200 mg 10 ma PC

Levofloxacin 5mg / ml yankho la kulowetsedwa kwa 100ml No. 1 botolo la Kraspharma OJSC

Ofloxacin 2mg / ml yankho la kulowetsedwa 100ml vial Synthesis OJSC

Mapiritsi a Levofloxacin 500mg No. 10

Mapiritsi a Levofloxacin 500mg No. 5

Levofloxacin-Teva 500mg No. 14 mapiritsi a Teva Pharmaceutical

Kusintha kwa Ziprofloxacin PFK CJSC, Russia

Levofloxacin Vertex CJSC, Russia

Levofloxacin Vertex CJSC, Russia

Levofloxacin Vertex CJSC, Russia

Levofloxacin wokutira mapiritsi 500mg No. 10 Health (Ukraine, Kharkov)

Levofloxacin wokutira mapiritsi 250mg No. 10 Health (Ukraine, Kharkov)

OfloxacinKievmedpreparat (Ukraine, Kiev)

Ofloxacin Darnitsa (Ukraine, Kiev)

Ofloxacin njira inf. 0.2% 100mlLekhim-Kharkiv

Ofloxacin njira inf. 0.2% 100mlLekhim-Kharkiv

Ofloxacin njira inf. 0.2% 100mlLekhim-Kharkiv

Ofloxacin njira inf. 0.2% 100mlLekhim-Kharkiv

Ciprofloxacin kulowetsedwa njira 0,2% 100mlNovofarm-Biosynthesis

Ciprofloxacin 0,25 g No. 10 tab.po.synthesis of OJSC (Russia)

Mafuta a Ofloxacin 0,3% 5 g.

Ciprofloxacin 0,5 g No. 10 tab.po.synthesis of OJSC (Russia)

Ciprofloxacin 200 mg 100 ml yankho d / mu. Fakitala ya mankhwala a Kelun (China)

Ofloxacin 2 mg / ml 100 ml yankho d / inf.Synthesis OJSC (Russia)

Mafuta a Ofloxacin adapangidwa kuti athane ndi matenda amaso.

Mafuta a Ofloxacin ndiwothandizira antiviral.

Chipangizocho chimatha kupezeka pafupifupi mankhwala aliwonse, chimadzikhazikitsa chokha, chifukwa chake nthawi zambiri chimayikidwa ndi ophthalmologists pochiza matenda osiyanasiyana.

Mafuta odana ndi bakiteriya okhala ndi ntchito yopachika polimbana ndi mabakiteriya monga:

• Salmonella
• Serratia.
• Shigella.
• Chlamydia
• Staphylococci.
• Brucella
• Helicobacter.
• Pilori.
• Pseudomonas aeruginosa.

Mafutawo amapangidwira kuthana ndi mawonetseredwe opatsirana komanso otupa m'dera la maso. Ikani mafuta ndi:

1. Barele.
2. Conjunctivitis.
3. Chlamydial matenda amaso.
4. Blepharitis.
5. Matenda am'maso.
6. Matenda a ziphuphu.

Mafutawo amagwiritsidwa ntchito ngati prophylactic ngati angapeze matenda, zovuta atamuchita opaleshoni, atachotsa thupi lakunja kuchokera kumaso kapena kuwonongeka kwa chivundikiro chamaso.

Mankhwalawa adapangira zochizira matenda ammaso, mawonekedwe a mafuta.

• Chowonjezera china ndi methylparaben.
• Propylparaben.
• Vaselini.
• Ofloxacin.

Mafutawo amapangidwa m'mapaketi a aluminium a magalamu atatu ndi asanu. Thumba lililonse limadzaza katoni.

Mafuta a Ofloxacin amapezeka m'matumba a 15 g

Mukamagwiritsa ntchito mafuta, mutha kudziwa zoyipa, izi:

1. Kumva kutentha.
2. Kuyabwa
3. Kusakhumudwitsidwa
4. Hyperemia.
5. Maso owuma kapena lachuration.
6. Musakonde kuunika.
7. Ziwengo

Ofloxacin contraindication ali motere:

• Ziwengo magawo a mankhwala.
• Ana ochepera zaka khumi ndi zisanu.
• Azimayi nthawi yoyamwa.
• Pa nthawi yoyembekezera, sitipangira kuvomerezedwa ndi dokotala popanda chilolezo.

Mafuta ogwiritsa ntchito kunja. Amayikidwa m'maso ndi Mzere wamamilimita 5.10.

Mzere uyenera kuyikiridwa m'maso a m'maso.

Gwiritsani ntchito kawiri kapena katatu pasanathe maola 12, kutengera mtundu wa matenda.

Ngati chlamydia, ikani maulendo asanu kapena kasanu ndi kamodzi mkati mwa maola 12.

Manja azitsukidwa tisanayikidwe, tikupangira mafuta othira kumaso kuchokera ku chubu.

Pulogalamuyi ikuwoneka motere:

Dzanja dontho lamkati m'munsi ndikuthira mafuta, kenako tsekani maso anu.

Njira ya mankhwala ndi milungu iwiri. Matenda a Chlamydial amafuna nthawi yayitali yothandizira.

Tikukulimbikitsani kuti oyendetsa magalimoto aleke kuyendetsa bwino mphindi 20 mutangogwiritsa ntchito.

Mtengo ku Russia ndi ma ruble 35, ku Ukraine 16 hhucnias.

Pali mitundu ingapo yofanana ndi mankhwalawa:

• Zitrox.
• Chloramphenicol.
• Phloxal.
• Oflomelide.
• Azitsin.
• Wilprafen.
• Vero-Ofloxacin.

Mankhwala a antibacterial a gulu la fluoroquinolone kuti agwiritsidwe ntchito mopepuka kwambiri mu ophthalmology

Mafuta amaso 0,3% yoyera, yoyera ndi tint yachikasu kapena chikasu.

Othandizira: methyl parahydroxybenzoate - 0,8 mg, propyl parahydroxybenzoate - 0,2 mg, petrolatum - mpaka 1 g.

5 g - machubu a zotayidwa (1) - mapaketi a makatoni.

Mankhwala othana ndi antibacterial ochulukirapo kuchokera pagulu la fluoroquinolones wogwiritsa ntchito mosiyanasiyana mu ophthalmology. Imagwira pa bakiteriya ya michere ya DNA gyrase, yomwe imatsimikizira kupindika ndipo, motero, kukhazikika kwa ma bacteria a DNA (kupangika kwa ma CD a ma bacteria kumawatsogolera kuti afe). Imakhala ndi bactericidal zotsatira.

Wogwira mtima kwambiri polimbana ndi tizilombo toyambitsa matenda: Staphylococcus spp. (kuphatikiza Staphylococcus aureus, Staphylococcus epidermidis), Streptococcus spp. (kuphatikizapo Streptococcus pneumoniae), Tizilombo toyambitsa matenda: Pseudomonas aeruginosa, Escherichia coli, Salmonella spp., Proteus spp. (kuphatikiza Proteus mirabilis), Morganella morganii, Shigella spp., Klebsiella spp. (kuphatikiza Klebsiella cloacae), Enterobacter spp., Serratia spp ,. tizilombo tosiyanasiyana: Chlamydia spp. (kuphatikiza Chlamydia trachomatis), Legionella spp., Mycoplasma spp., anaerobes: Propionibacterium acnes.

Mu maphunziro oyesera zinapezeka kuti pambuyo pa topical management ofloxacin amapezeka mu cornea (cornea), conjunctiva, ocular minofu, sclera, iris, ciliary body komanso mu anterior chipinda cha diso.

Kugwiritsidwanso ntchito mobwerezabwereza kumathandizanso kukwaniritsa zochizira zozungulira zaloloacacin m'thupi la vitreous. Kuphatikiza kwakukulu kwa mankhwalawa kumapangidwa ndi minofu ya maso kuposa kuseka kwamaso.

Pakangogwiritsidwa ntchito kamodzi pamafuta okuta pafupifupi 1 cm (pafupifupi 0.12 mg ofloxacin), Cmax ofloxacin mu conjunctiva ndi sclera amafikiridwa patatha mphindi 5, pambuyo pake ndende yaloloacacin imayamba kuchepa. Cmax ofloxacin mu madzi am'maso ndi ziphuphu kumachitika pambuyo pa 1 h.

- bakiteriya matenda am'makutu, conjunctiva ndi ziphuphu (bakiteriya keratitis ndi zilonda zam'mimba, blepharitis, conjunctivitis, blepharoconjunctivitis),

- meibomite (barele), dacryocystitis,

- matenda a maso,

- kupewa matenda opatsirana pambuyo pake pambuyo pa kuchitapo kanthu pochita opaleshoni yokhudzana ndikuchotsa thupi lakunja ndi kuvulala kwa diso.

- Matenda a conjunctivitis osakhala mabakiteriya,

- ana ndi achinyamata osakwana zaka 15,

- Hypersensitivity pazigawo za mankhwala ndi zina zomwe zimachokera ku quinolone.

Kwathu. Kwa m'munsi chikope cha wakhudzidwa 2-3 zina / tsiku anagona 1 cm wa mafuta (0,12 mg ofloxacin). At matenda a chlamydial mafuta amayikidwa 5-6 nthawi / tsiku.

Kuti muthandizire mafuta, kokerani khungu lanu m'munsi mosamala, ndikumakankhira chubu, ndikulowetsani mzere wautali wa 1 cm mumtolo wothandizirana nawo. Kenako tsekani chikope ndikuyendetsa eyeboni kuti muzigawa mafuta moyenerera.

Kutalika kwa njira ya chithandizo sikupitilira milungu iwiri (ndi matenda a chlamydial, maphunzirowo amafikira mpaka masabata 4-5).

Zomwe zimachitika: kumva kutentha ndi kusasangalala m'maso, kuthamanga, kuyabwa ndi kuwuma kwa conjunctiva, Photophobia, lacrimation, thupi lawo siligwirizana. Nthawi zambiri, zizindikirozi zimakhala zazifupi.

Zambiri pa mankhwala osokoneza bongo a mankhwala siziperekedwa.

Pakupereka Ofloxacin, pamodzi ndi madontho ena am'maso / mafuta, mankhwalawa ayenera kugwiritsidwa ntchito mosagwirizana ndi mphindi 15, zomwe Ofloxacin akuyenera kugwiritsidwa ntchito komaliza.

Osavala magalasi ofewa munthawi yamankhwala.

Ndikulimbikitsidwa kuvala magalasi (chifukwa cha kupangika kwa Photophobia), komanso kupewa kuyatsa nthawi yayitali.

Ofloxacin sayenera kutumikiridwa mwachisawawa kapena mu chipinda chakunja cha diso.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Mukangogwiritsa ntchito mankhwalawa, kuzindikira koyenera kumatha kuchitika, komwe kumatha kubweretsa zovuta mukamayendetsa komanso mukamagwiritsa ntchito zinthu zina. Ndikulimbikitsidwa kuti muyambe kugwira ntchito (kuyendetsa) mphindi 15 mutatha kugwiritsa ntchito mankhwalawa.

Mimba komanso kuyamwa

Kugwiritsa ntchito mankhwalawa kumatsutsana

komanso yoyamwitsa.

Gwiritsani ntchito paubwana

Mankhwalawa ali ophatikizika mwa ana ndi achinyamata osakwana zaka 15.

Mankhwala ndi mankhwala.

Mndandanda B. Mankhwalawa amayenera kusungidwa kuti ana asawatenthe mpaka kutentha 15 mpaka 25 ° C. Moyo wa alumali ndi zaka zitatu.

Madokotala amafufuza

Kuunikiridwa kwa madokotala kungathandize kumvetsetsa mphamvu ya mankhwalawa pochita:

Eugene, wothandizira: Nthawi zambiri odwala amabwera ndi matenda a barele. Matenda osasangalatsa awa amakumana ndi anthu ambiri azaka zosiyanasiyana. Zochizira, nthawi zambiri ndimalimbikitsa mafuta a Ofloxacin kwa odwala. Mankhwalawa ndi otsika mtengo komanso ogwira ntchito. Zikatero amatulutsa antibacterial zotsatira. Zochita zanga, palibe ndemanga zoyipa.

Yuri, ophthalmologist: Mafuta ndi mankhwala odziwika otchipa. Nthawi zambiri zotchulidwa ngati zovuta mankhwala bakiteriya. Kuchita bwino kumawonedwa ndi chlamydia wa maso. Mankhwalawa ndiwotalikirapo, koma ogwira ntchito. Nthawi zambiri, amalolera bwino ndipo samayambitsa zovuta.

Alexander, ophthalmologist: Mankhwalawa amagwira ntchito popanga zotupa ndi zotupa zama bakiteriya. Ndikupereka monga njira yovuta yochizira matenda a blepharitis, conjunctivitis, balere. Odwala samakonda kudandaula za mafuta.

Ndemanga za Makasitomala

Ndemanga za odwala omwe adalandira mankhwalawa:

Julia, wazaka 35: Dotolo adalangiza kuyika mafuta ndi barele. Chithunzicho chidatsegulidwa patatha masiku awiri kuchokera ku mawonekedwe. Mafuta anathandizira kuteteza diso kuti lisawonongedwe ndi bakiteriya. Palibe zoyipa zomwe zidachitika. Ndimakonda kuti mankhwalawa ndi otsika mtengo komanso okwera mtengo. Sindinamwe mankhwala ena munthawi ya chithandizo.

Nadezhda, wazaka 28: Unakumana ndi matenda osasangalatsa monga blepharitis. Dokotala wamaso amafunikira chithandizo chovuta kwambiri. Zinaphatikizanso kupaka mafuta a Ofloxacin. Njira yodalirayi ndiyosasangalatsa. Kwakanthawi. Kwenikweni patatha pafupifupi mphindi 20, zonse zidabwezedwa.

Igor, wazaka 37: Dokotala wamaso adalemba mafuta ngati chithandizo chovuta cha bakiteriya conjunctivitis. Poyamba, pang'ono ankakhulupirira mphamvu ya mankhwala otsika mtengo ngati amenewa. Pasanathe masiku 5, anachotsa kutupa. Anayika mafuta pambuyo kutsatira. Ndinkakonda kuti, mosiyana ndi mankhwala ena, mafuta awa ndi otsika mtengo. Zizindikiro zosasangalatsa komanso zoyipa sizinachitike munthawi yamankhwala.

Ofloxacin malangizo mafuta ogwiritsa ntchito

Mafutawo amapangidwira kuthana ndi mawonetseredwe opatsirana komanso otupa m'dera la maso. Ikani mafuta ndi:

1. Barele.
2. Conjunctivitis.
3. Chlamydial matenda amaso.
4. Blepharitis.
5. Matenda am'maso.
6. Matenda a ziphuphu.

Mafutawo amagwiritsidwa ntchito ngati prophylactic ngati angapeze matenda, zovuta atamuchita opaleshoni, atachotsa thupi lakunja kuchokera kumaso kapena kuwonongeka kwa chivundikiro chamaso.

Zogwirizana

Mafutawa ndi otsika mtengo komanso ogwira ntchito. Koma ndikofunikira kugwiritsira ntchito mosamalitsa malinga ndi malangizo, mwinanso, pambuyo poti mpumulo wabwinobwino wazizindikiro, njira yotupa ingakulire. Izi ndi gawo la maantibayotiki. Ponena za ma analogi, sikuti onse omwe akuwonetsedwa ali ndi mafuta omwe ali ndi mafuta a Ofloxacin. Mwachitsanzo, chloramphenicol ndi mankhwala enanso opha tizilombo. Nanga machitidwe a chithandizo azikhala omwewo? Osati chowonadi.

Zotsatira za pharmacological

Farmgroup: wothandizira antimicrobial - fluoroquinolone.
Zochita zamankhwala: Wothandizila kwambiri ma antimicrobial wothandizila kuchokera pagulu la fluoroquinolones, amagwira pa michere ya michere ya DNA gyrase, yomwe imapereka supercoiling, ndi zina zambiri. kukhazikika kwa mabakiteriya a DNA (kuphatikizika kwa maunyolo a DNA kumabweretsa kufa kwawo). Imakhala ndi bactericidal zotsatira.
Omvera mu vivo: aerobes abwino a gram: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae. Ma grram-negative aerobes: Enterobacter cloacae, Haemophilus fuluwenza, Proteus mirabilis, Pseudomonas aeruginosa, Serratia marcescens.Anaerobes: Propionibacterium acnes.
Mu vitro atengeke: aerobes abwino a gramu: Enterococcus faecalis, Staphylococcus hominus, Listeria monocytogenes, Staphylococcus simulans, Staphylococcus capitis, Streptococcus pyogene. Ma gror-negative aerobes: Acinetobacter calcoaceticus var. anitratus, Klebsiella pneumoniae, Acinetobacter calcoaceticus var. lwoffii, Moraxella (Branhamella) catarrhalis, Citrobacter diversus, Moraxella lacunata, Citrobacter freundii, Morganella morganii, Enterobacter aerogene, Neisseria gonorrhoeae, Enterobacter agglomerans, Pseudomonas acidovorans, Escherichomella cholefenella pheudis coli
Ena: Chlamydia trachomatis.

Mafuta a Ofloxacin, zikuwonetsa

Ophthalmology: bakiteriya zam'mimba zilonda zam'mimba, conjunctivitis, blepharitis, meibomite (balere), dacryocystitis, keratitis, matenda a chlamydial a maso, kupewa matenda opatsirana pambuyo pake pambuyo pakuchita opaleshoni yochotsa thupi lakunja ndi kuvulala kwa diso.
Mchitidwe wa ENT: bakiteriya wakunja komanso wapakati wa otitis media, atitis media yodzikongoletsa kwa eardrum kapena tympanopuncture, kupewa matenda opatsirana poyambitsa opaleshoni.

Mlingo ndi makonzedwe

Kwathu. Kwa m'munsi chikope cha wakhudzidwa 2-3 zina / tsiku anagona 1 cm wa mafuta (0,12 mg ofloxacin). Ndi matenda a chlamydial, mafuta amayikidwa nthawi 5-6 / tsiku.

Kuti muthandizire mafuta, kokerani khungu lanu m'munsi mosamala, ndikumakankhira chubu, ndikulowetsani mzere wautali wa 1 cm mumtolo wothandizirana nawo. Kenako tsekani chikope ndikuyendetsa eyeboni kuti muzigawa mafuta moyenerera.

Kutalika kwa njira ya chithandizo sikupitilira milungu iwiri (ndi matenda a chlamydial, maphunzirowo amafikira mpaka masabata 4-5).

Njira zopewera kupewa ngozi

Kutalika konse kwa njira ya chithandizo sikupitilira miyezi iwiri. Pewani kuwonetsedwa ndi kuwala kwa dzuwa ndi kuwala kwa UV.

Ngati chitukuko cha mavuto kuchokera chapakati mantha dongosolo, thupi lawo siligwirizana, pseudomembranous colitis, kusiya mankhwala ndikofunikira. Ndi pseudomembranous colitis, yatsimikiziridwa colonoscopically ndi / kapena histologically, pakamwa pa vancomycin ndi metronidazole akuwonetsedwa.

Kawirikawiri zomwe zimachitika tendonitis zimatha kuyambitsa kupuma kwa tendon (makamaka Achilles tendon), makamaka kwa okalamba. Panthawi ya chizindikiro cha tendonitis, ndikofunikira kusiya mankhwalawa, kuyambitsa tendon ya Achilles ndikuyang'ana kwa akatswiri a zamankhwala.

Odwala omwe ali ndi vuto la impso kapena kwa chiwindi, kuyang'aniridwa kwa ofloxacin mu plasma kuyenera kuyang'aniridwa. Mwa kuperewera kwambiri kwaimpso ndi kwa chiwindi, chiopsezo cha zotsatira za poizoni chikuwonjezeka.

Ofloxacin

200 mg mapiritsi okhala ndi mafilimu - 5 zaka.

400 mg mapiritsi okhala ndi mafilimu - zaka 5.

mafuta odzola 0,3% - zaka 5. Pambuyo kutsegulira - 6 milungu.

2 mg / ml kulowetsedwa mu 0.9% sodium kolorayidi - 2 years.

Osagwiritsa ntchito tsiku lotha ntchito likusonyezedwa pa phukusi.