Mafanizo
Forethine (mapiritsi) Kutalika: 37
Wopanga: Kachemala-Leksredstva (Russia)
Kutulutsa Mafomu:
- Tab. 50 mg, 30 ma PC., Mtengo kuchokera ku ma ruble 57
- Tab. 50 mg, 60 ma PC., Mtengo kuchokera ku ma ruble 99
Malangizo ogwiritsira ntchito
Formetin ndimalo otsika mtengo kwambiri a Glucofage, omwe amapangidwa kuti achepetse shuga m'magazi. Amapezeka m'mapiritsi okhala ndi 0,5, 0,85 kapena 1 g wa metformin. Zitha kuyambitsa kusokonezeka kwa dongosolo la kugaya, zotupa pakhungu, komanso ngati mankhwala osokoneza bongo - hypoglycemia ndi lactic acidosis atha kufa.
Mndandanda wa mankhwala Fomu
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 53.
Wopanga: Merck Sante SAA.S. (France)
Kutulutsa Mafomu:
- Mapiritsi 500 mg, 30 ma PC., Mtengo kuchokera ku ma ruble 110
- Mapiritsi 1000 mg, 30 ma PC., Mtengo kuchokera ku ma ruble 185
Malangizo ogwiritsira ntchito
French mankhwala zochizira mtundu 2 shuga. Kugulitsidwa pamapiritsi okhala ndi 500 mpaka 1000 mg ya metformin monga chokhacho chophatikiza. Pali zotsutsana, motero, musanatenge Glucofage, ndikofunikira kufunsa katswiri.
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 52.
Wopanga: Akrikhin (Russia)
Kutulutsa Mafomu:
- Mapiritsi 500 mg, 60 ma PC., Mtengo kuchokera ku ma ruble 109
- Mapiritsi 850 mg, 60 ma PC., Mtengo kuchokera ku ma ruble 190
Malangizo ogwiritsira ntchito
Gliformin ndi mankhwala am'nyumba pochizira matenda amtundu wa 2. Kugulitsidwa mu mapiritsi ndi metformin monga gawo limodzi lokhazikika (kuchuluka kwa 250 kapena 500 mg ndikotheka). Gliformin ali ndi mndandanda wambiri wa zotsutsana, kotero musanayambe chithandizo, onetsetsani kuti muwerenga malangizo omwe angagwiritsidwe ntchito.
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 119.
Wopanga: Vörwag Pharma GmbH & Co KG (Germany)
Kutulutsa Mafomu:
- Mapiritsi 1000 mg, 30 ma PC., Mtengo kuchokera 176 rubles
- Mapiritsi 850 mg, 60 ma PC., Mtengo kuchokera ku ma ruble 190
Malangizo ogwiritsira ntchito
Mankhwala enanso a matenda a shuga omwe amapezeka m'mapiritsi. Kugulitsidwa makatoni mapiritsi 30 okhala ndi metformin hydrochloride monga mankhwala othandizira. Contraindified pa mimba ndi yoyamwitsa.
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 121.
Wopanga: Hemofarm A.D. (Serbia)
Kutulutsa Mafomu:
- Tab. 500 mg, 60 ma PC., Mtengo kuchokera 178 ma ruble
- Mapiritsi 850 mg, 60 ma PC., Mtengo kuchokera ku ma ruble 190
Malangizo ogwiritsira ntchito
Metformin ndi mankhwala achi Serbia hypoglycemic ogwiritsira ntchito mkati. Kuphatikizika kwa mapiritsi kumakhala ndi chophatikizira cha dzina lomweli muyezo wa 500 kapena 850 mg. Amalembera mankhwalawa mtundu wa matenda ashuga 2 (achikulire), makamaka ngati ali ndi kunenepa kwambiri.
Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 214.
Wopanga: Berlin-Chemie / Menarini Pharma GmbH (Germany)
Kutulutsa Mafomu:
- Tab. 500 mg, 60 ma PC., Mtengo kuchokera 271 rubles
- Mapiritsi 850 mg, 60 ma PC., Mtengo kuchokera ku ma ruble 190
Malangizo ogwiritsira ntchito
Siofor ndi mapiritsi achijeremani omwe amakonzekera zochizira matenda a shuga 2. Metformin hydrochloride mu mlingo wa 500 mpaka 1000 mg umagwiritsidwa ntchito ngati chinthu chogwira ntchito. Kugulitsidwa m'makatoni a mapiritsi 60.
Analogs popanga ndi chisonyezo chogwiritsidwa ntchito
| Mutu | Mtengo ku Russia | Mtengo ku Ukraine |
|---|---|---|
| Bagomet Metformin | -- | 30 UAH |
| Glucofage metformin | 12 rub | 15 UAH |
| Glucophage xr metformin | -- | 50 UAH |
| Reduxin Met Metformin, Sibutramine | 20 rub | -- |
| Dianormet | -- | 19 UAH |
| Diaformin metformin | -- | 5 UAH |
| Metformin metformin | 13 rub | 12 UAH |
| Metformin sandoz metformin | -- | 13 UAH |
| Siofor | 208 rub | 27 UAH |
| Fomu metformin hydrochloride | -- | -- |
| Emnorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Metamine Metformin | -- | 20 UAH |
| Metamine SR Metformin | -- | 20 UAH |
| Metfogamma metformin | 256 rub | 17 UAH |
| Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Metformin Canon metformin, ovidone K 90, wowuma chimanga, crospovidone, magnesium stearate, talc | 26 rub | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 rub | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Farmland Metformin | -- | -- |
Mndandanda womwe uli pamwambapa wa analogies ya mankhwala, omwe akuwonetsa formethine oloweza, ndizabwino kwambiri chifukwa zimakhala ndi zinthu zomwe zimagwirizana ndipo zimagwirana molingana ndi chisonyezo chogwiritsidwa ntchito
Kuphatikizika kosiyanasiyana, kungagwirizane mukuwonetsa ndikugwiritsa ntchito njira
| Mutu | Mtengo ku Russia | Mtengo ku Ukraine |
|---|---|---|
| Rosiglitazone wothandiza, metformin hydrochloride | -- | -- |
| Glibenclamide Glibenclamide | 30 rub | 7 UAH |
| Maninyl Glibenclamide | 54 rub | 37 UAH |
| Glibenclamide-Health Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 rub | 43 UAH |
| Bisogamma Glyclazide | 91 rub | 182 UAH |
| Glidiab Glyclazide | 100 rub | 170 UAH |
| Diabeteson MR | -- | 92 UAH |
| Diagnizide mr Gliclazide | -- | 15 UAH |
| Glidia MV Gliclazide | -- | -- |
| Glykinorm Gliclazide | -- | -- |
| Gliclazide Gliclazide | 231 rub | 44 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Glyclazide-Health Gliclazide | -- | 36 UAH |
| Glioral Glyclazide | -- | -- |
| Diagnizide Gliclazide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Diadeon gliclazide | -- | -- |
| Glyclazide MV Gliclazide | 4 rub | -- |
| Amaril | 27 rub | 4 UAH |
| Glemaz glimepiride | -- | -- |
| Glian glimepiride | -- | 77 UAH |
| Glimepiride Glyride | -- | 149 UAH |
| Glimepiride diapiride | -- | 23 UAH |
| Guwa | -- | 12 UAH |
| Glimax glimepiride | -- | 35 UAH |
| Glimepiride-Lugal glimepiride | -- | 69 UAH |
| Clay glimepiride | -- | 66 UAH |
| Diabrex glimepiride | -- | 142 UAH |
| Meglimide glimepiride | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| Perinel glimepiride | -- | -- |
| Glempid | -- | -- |
| Wokongola | -- | -- |
| Glimepiride glimepiride | 27 rub | 42 UAH |
| Glimepiride-teva glimepiride | -- | 57 UAH |
| Glimepiride Canon glimepiride | 50 rub | -- |
| Glimepiride Pharmstandard glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| Glamepiride diamerid | 2 rub | -- |
| Amaryl M Limepiride Micronized, Metformin Hydrochloride | 856 rub | 40 UAH |
| Glibomet glibenclamide, metformin | 257 rub | 101 UAH |
| Glucovans glibenclamide, metformin | 34 rub | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Gluconorm | 45 rub | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| Janumet metformin, sitagliptin | 9 rub | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 rub | 1195 UAH |
| Tripride glimepiride, metformin, pioglitazone | -- | 83 UAH |
| Comboglize XR metformin, saxagliptin | -- | 424 UAH |
| Comboglyz Prolong metformin, saxagliptin | 130 rub | -- |
| Gentadueto linagliptin, metformin | -- | -- |
| Vipdomet metformin, alogliptin | 55 rub | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 rub | -- |
| Voglibose Oxide | -- | 21 UAH |
| Glutazone pioglitazone | -- | 66 UAH |
| Dropia Sanovel pioglitazone | -- | -- |
| Januvia sitagliptin | 1369 rub | 277 UAH |
| Galvus vildagliptin | 245 rub | 895 UAH |
| Onglisa saxagliptin | 1472 rub | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 rub | 1250 UAH |
| Trazhenta linagliptin | 89 rub | 1434 UAH |
| Lixumia lixisenatide | -- | 2498 UAH |
| Malo a Guarem Guar | 9950 rub | 24 UAH |
| Insvada repaglinide | -- | -- |
| Novonorm Repaglinide | 30 rub | 90 UAH |
| Repodiab Repaglinide | -- | -- |
| Baeta Exenatide | 150 rub | 4600 UAH |
| Baeta Long Exenatide | 10248 rub | -- |
| Viktoza liraglutide | 8823 rub | 2900 UAH |
| Saxenda liraglutide | 1374 rub | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 rub | 3200 UAH |
| Invocana canagliflozin | 13 rub | 3200 UAH |
| Jardins Empagliflozin | 222 rub | 566 UAH |
| Trulicity Dulaglutide | 115 rub | -- |
Kodi mungapeze bwanji analogue yotsika mtengo ya mankhwala okwera mtengo?
Kuti mupeze chiwonetsero chotsika mtengo cha mankhwala, chofananira kapena chofanana, choyambirira timalimbikitsa kulabadira kapangidwe kake, zomwe ndi zinthu zomwezo zomwe zikugwira komanso zomwe zikugwiritsidwa ntchito. Zomwe zimagwiritsidwanso mosiyanasiyana ndi mankhwalawa zimawonetsa kuti mankhwalawo ndi ofanana ndi mankhwalawo, monga mankhwala ena kapena mitundu ina. Komabe, musaiwale za zovuta zomwe zimagwiritsidwa ntchito ndi mankhwala ofanana, omwe angakhudze chitetezo ndi kugwiranso ntchito. Musaiwale za malangizo a madotolo, kudzipereka nokha kungawononge thanzi lanu, chifukwa chake onani dokotala wanu musanagwiritse ntchito mankhwala.
Zabwino za piritsi kukonzekera
Zizindikiro zazikulu pakugwiritsa ntchito mankhwalawa ndi motere:
- kukhalapo kwa metabolic syndrome kapena mawonekedwe a insulin kukana,
- Monga lamulo, pamaso pa insulin kukana, kunenepa kwambiri kukukulira kwa odwala, chifukwa cha zotsatira za metformin komanso kuyang'anira zakudya zapadera zamagulu, kuchepa thupi pang'onopang'ono kumatheka.
- ngati pali kuphwanya kwa kulekerera kwa glucose,
- Matenda a ovary ovulala kwambiri,
- shuga yodalira matenda a shuga monga monotherapy kapena gawo limodzi la chithandizo chovuta kwambiri,
- mawonekedwe a shuga omwe amadalira insulin molumikizana ndi jakisoni wa insulin.
Ngati tiyerekeza mankhwala a Fomutiamu ndi mankhwala ena ochepetsa shuga, zotsatirazi zazikuluzikulu za metformin ziyenera kufotokozeredwa:
- Zake pakuchepetsa kukana kwa insulin wodwala. Metformin hydrochloride imatha kuwonjezera kukhudzika kwa maselo ndi minyewa ku glucose wopangidwa ndi kapamba.
- Kutenga mankhwalawo kumayendetsedwa ndi mayamwidwe ake ndi ziwalo zam'mimba. Chifukwa chake, kuchepetsa kuchepa kwa shuga ndi matumbo kumakwaniritsidwa.
- Imathandizira kuletsa shuga wa chiwindi, zomwe zimatchedwa kuperekera shuga.
- Zimathandizira kuchepetsa kulakalaka, komwe ndikofunikira kwambiri kwa odwala matenda ashuga onenepa kwambiri.
- Zimakhala ndi phindu pa cholesterol, kuchepetsa zoyipa ndikuwonjeza zabwino.
Kuphatikiza apo, mankhwalawa amathandizira kuti magawo azikhala ochepa.
Malangizo ogwiritsira ntchito mapiritsi
Malangizo a formethine ogwiritsira ntchito ali ndi kunena kuti mankhwalawa amapezeka piritsi la mawonekedwe a biconvex oyera mapiritsi.
Kuphatikizika kwa mankhwalawa kumaphatikizapo ntchito yogwira ntchito ya Metformin hydrochloride ndi zigawo zina zothandizira mu mawonekedwe a magnesium stearate, povidone ndi croscarmellose sodium.
Mlingo wotsatira wa mankhwalawa amaperekedwa pamsika wa pharmacological - 0,5 g, 0,85 g ndi 1 g yogwira ntchito. Kutengera ndi kuopsa kwa hyperglycemia, dokotala amapereka mankhwala omwe amafunikira. Mapiritsi onse a formin amatha kugulidwa m'makatoni a zidutswa 30, 60 kapena 120. Kugwiritsa ntchito kwawo ndizotheka pokhapokha ngati adokotala adanenanso (masiku ano azimayi ambiri amagwiritsa ntchito njira yochepetsera thupi).
Njira yoyendetsera ndi kumwa Mlingo wakhazikitsidwa kwa wodwala aliyense payekhapayekha, kutengera magawo ake:
- kuopsa kwa matenda komanso kuchuluka kwa kuchuluka kwa shuga m'magazi
- gulu la odwala ndi odwala and
- kukhalapo kwa matenda oyanjana.
Musanayambe chithandizo, ndikulimbikitsidwa kuyesedwa ndikuyesedwa kuti mupeze zoopsa zomwe zingachitike ndikuwonetsa kugwiritsidwa ntchito molakwika pogwiritsa ntchito mankhwalawa.
Mankhwala Formetin, monga lamulo, amatengedwa molingana ndi malingaliro otsatirawa:
- Pakamwa pakudya, kumwa madzi ambiri.
- Mankhwala oyambira ayenera kuyamba ndi kuchuluka kwa ntchito yogwira ndipo akhale ma milligram mazana asanu patsiku.
- Pakumapeto kwa nthawi (nthawi zambiri pakadutsa milungu iwiri), adotolo, kutengera zotsatira za mayeso ndi kuchuluka kwa glucose m'magazi, amapanga chisankho pakusintha kwa mankhwalawa. Tiyenera kukumbukira kuti pafupifupi tsiku lililonse mlingo wa 500 mpaka 1000 mg wa yogwira metformin hydrochloride.
- Kuchuluka kwa mankhwala osokoneza bongo omwe amapezeka patsiku sikuyenera kupitirira 3000 mg ya mankhwala othandizira, kwa anthu achikulire chiwerengerochi ndi 1000 mg.
Mutha kumwa formin kamodzi kapena kangapo patsiku, kutengera mtundu womwe wakhazikitsidwa.
Ngati wodwala akufunika Mlingo wambiri wa mankhwalawa, ndibwino kumawagawaniza kangapo patsiku.
Mawonekedwe olakwika a mankhwala
Mankhwala amatha kusokoneza thupi, kuwonetsa zochita zake zoipa.
Kuti muchepetse kuwopsa kwa kupezeka kwawo, ndikofunikira kutsatira malangizo onse a akatswiri azachipatala.
Ndikulimbikitsidwanso kuti muzolowere zomwe mukudziwa zomwe zimapezeka piritsi.
Zotsatira zoyipa zomwe zimachitika chifukwa chotenga mapiritsi a Formetin, mosatengera Mlingo,
- kupezeka kwa mavuto osiyanasiyana ndi m'mimba thirakiti. Izi ndi, zoyambirira, monga kupusa mseru ndi kusanza, kutsegula m'mimba, kutuphuka ndi kukomoka pamimba.
- mankhwala kumawonjezera chiopsezo cha anorexiaꓼ
- mwina kusintha kwa kakomedwe, komwe kumawonekera pakachitika chinthu chosasangalatsa chachitsulo chamkati pamlomo
- kuchepa kwa vitamini B, kumakukakamizani kuti mumwe mankhwala ena owonjezera ndi mankhwala othandizira ꓼ
- chiwonetsero cha kuchepa magazi
- ndi bongo wambiri, pamakhala chiwopsezo cha hypoglycemiaꓼ
- mavuto ndi khungu, ngati pali kuwonetseredwa kwa thupi lawo siligwirizana.
Odwala ena amawona kuti formin ndi antiotic. M'malo mwake, mankhwala sakhala m'gulu la mankhwala otere. Nthawi yomweyo, kwa ana, kugwiritsa ntchito mankhwala kuti athetse hyperglycemia ndi koletsedwa.
Zotsatira zoyipa zimathanso kuchitika chifukwa chogwiritsa ntchito molakwika mankhwalawo kapena pogwiritsa ntchito mankhwala enaake. Kuphatikiza Fomu ndi zida zina zamankhwala (mwanjira ya mapiritsi, kuyimitsidwa, mayankho a jekeseni amakalasi osiyanasiyana ndi magulu) ndizotheka kokha mwa chilolezo cha katswiri wazachipatala.
Kodi zoletsa kugwiritsa ntchito mankhwalawa ndi ziti?
Kuponderezedwa kwa formethine kumasonyezedwa patsamba lamasamba mpaka kukonzekereratu.
Wopanga amafotokozera anthu onse omwe angakhale ogwiritsa ntchito mwatsatanetsatane za milandu yomwe sikovomerezeka kugwiritsa ntchito mankhwalawa.
Kuphatikiza apo, malangizowo ali ndi chidziwitso chomwe formmetin imagwirizana ndi omwe mankhwalawa ndi zinthu.
Sizoletsedwa kumwa mankhwala ngati zotsatirazi zadziwika:
- Acidosis mu mitundu kapena pachimake.
- Atsikana pa nthawi yobereka mwana kapena yoyamwitsa.
- Odwala a zaka zopuma pantchito, makamaka atatha zaka makumi asanu ndi limodzi ndi zisanu.
- Kusagwirizana ndi gawo la mankhwalawa, chifukwa kuyambitsidwa kwa ziwengo zovuta kumatheka.
- Ngati wodwala wapezeka ndi vuto la mtima.
- Ndi vuto lapamtima lakale ndi matenda ashuga.
- Ngati hypoxia imachitika.
- Pakusowa kwamadzi, komwe kumayambanso chifukwa cha matenda osiyanasiyana opatsirana.
- Kugwira ntchito kwambiri.
- Matenda am'mimba, kuphatikizapo kukhalapo kwa zilonda.
- Kulephera kwa chiwindi.
Kuphatikiza apo, kuphatikiza kwa chithandizo chamankhwala ndi mowa (mowa pakuwonetsedwa kulikonse) sikovomerezeka.
Ngati wodwala ali ndi ntchito ya impso, chiopsezo chokhala ndi lactic acidosis chitha kuchuluka, chifukwa kuchuluka kwa lactic acid mthupi kumayamba kudziunjikira.
Ndemanga za akatswiri azachipatala ndi odwala ndi ma analogu
Malongosoledwe amapangidwe a mapiritsi a Foromu ndi kuwunika kambiri kwa ogula akuwonetsa ntchito yake kwambiri.
Kuphatikiza apo, odwala ambiri amawonetsa kulera kosavuta kwa mankhwalawa komanso kusapezeka kwa zovuta zosiyanasiyana.
Formmetin ili ndi mtengo m'mafakitala a ma ruble zana ndipo zimatengera zinthu zingapo.
Zinthu zomwe zimapangitsa mtengo wa mankhwalawa kukhala motere:
- kuchuluka kwa mapiritsi pa paketi iliyonse
- Mlingo wa mankhwala active
- mzinda wogulitsa ndi mankhwala.
Mtengo wa formin ndi dongosolo la kutsika kwambiri kuposa mankhwala ena omwe ali ndi mankhwala othandizira a metformin hydrochloride. Ichi ndichifukwa chake, akatswiri ambiri azachipatala amalimbikitsa kugwiritsa ntchito chida ichi kuti matenda a matenda ashuga asinthe. Ndemanga za madotolo zokhudza kuthamanga kwa shuga m'magazi, kusalolera pachitukuko cha kukana insulini, titilole kunena kuti Formetin ndi njira yosankhira bajeti yomwe imabweretsa zotsatira zabwino.
Mitundu ya formimetin pamsika wama pharmacological imayimilidwa zambiri. Izi zikuphatikiza mankhwala osokoneza bongo omwe ali ndi mankhwala enaake, omwe amatha kukhala osiyana, koma ali ndi vuto lofananalo. Mukafuna cholowa m'malo, muyenera kupeza upangiri wa dokotala yemwe angakupatseni mwayi woyenera.
Mankhwala otsatirawa akuphatikizidwa ndi manambala a Fomu yametmetin:
Mankhwala onse omwe ali pamwambawa ndi ena mwa mapiritsi ochepetsa shuga omwe ali ndi vuto la hypoglycemic. Chofunikira chachikulu ndi metformin hydrochloride. Mankhwalawa sikuti amasiyana ndi Foromu. Kusiyanako kungakhale ndi kuchuluka kwa zoyipa kapena zosemphana ndi zomwe zikuwonetsedwa, komanso mtengo wa mankhwalawo.
Nthawi zina, formin imafotokozedwa ngati mankhwala ophatikizika pogwiritsa ntchito mankhwala monga atorvastatin kapena glycine.
Zomwe ndimankhwala opatsirana a shuga zomwe zingathandize kuphatikiza shuga m'magazi, katswiri adzanena mu kanema mu nkhaniyi.
Formetin: malangizo ogwiritsira ntchito, mtengo, analogi
Formetin ndi mankhwala yogwira a metformin hydrochloride. Mlingo: 0,5 g, 0,85 g kapena 1 ma Analogs: Glformin, Metadiene, Nova Met, NovoFormin, Siofor, Sofamet.
Zinthu zothandiza: croscarmellose sodium, sing'anga molecheni povidone (polyvinylpyrrolidone), magnesium stearate yamafuta azamalonda.
Kutulutsa mawonekedwe: mapiritsi ozungulira ozungulira amiyala yokhala ndi mawonekedwe ndi chiopsezo (mulingo wa 0,5 g) ndi mapiritsi oyera a biconvex oyera okhala ndi chiopsezo kumbali imodzi (Mlingo wa 0.85 g ndi 1.0 g).
Zizindikiro zamankhwala
Formethine imachepetsa kuyamwa kwa glucose kuchokera m'matumbo, imalepheretsa gluconeogeneis mu chiwindi, imathandizira kutulutsa kwa glucose, ndikuwonjezera chidwi cha minofu kukonzekera kwa insulin.
Pankhaniyi, formethine:
- Zilibe kukhudzana ndikupanga insulin ndi maselo a beta omwe amapezeka mu kapamba.
- Sizipangitsa kukhazikika kwa dziko la hypoglycemic.
- Amachepetsa kuchuluka kwa lipoprotein otsika ndi triglycerides m'magazi.
- Amachepetsa kunenepa kwambiri, amakhala olimba.
- Imakhala ndi fibrinolytic chifukwa chokakamira kwa minofu wa plasminogen activator.
Formaline, pambuyo pakamwa pakamwa, imatengedwa pang'onopang'ono kuchokera kumimba. Kuchuluka kwa mankhwala a bioavava pambuyo poti mugwiritse ntchito muyezo pafupifupi 60%.
Kuchuluka kwa mankhwalawa kwa magazi m'magazi kumachitika patatha maola awiri ndi awiri kuchokera pakatikati.
Forethine pafupifupi samamangirira mapuloteni a plasma, amadziunjikira m'chiwindi, impso, minofu, ma gasi a salivary, ndipo amamuchotsa impso mu mawonekedwe osayenera. Hafu ya moyo wa chinthucho ndi maola 1.5 - 4.5.
Tcherani khutu! Ngati wodwalayo wasokoneza ntchito yaimpso, kudzikundikira kwa mankhwala m'thupi ndikotheka.
Zizindikiro zogwiritsidwa ntchito
Mankhwala amathandizidwa ndi mtundu wachiwiri wa matenda a shuga, pamene chithandizo chamankhwala sichinabweretse zotsatira zabwino (mwa odwala omwe ali ndi kunenepa kwambiri), zonsezi zikuwonetsedwa ndi malangizo a mankhwalawa.
Mlingo wa mankhwalawa amatchulidwa ndi dokotala aliyense payekha kwa wodwala aliyense. Kusiyana kwa Mlingo kumachitika chifukwa cha kuchuluka kwa shuga m'magazi. Mapiritsi a Forethine ayenera kumwedwa panthawi yomwe wodwala watenga chakudya, osafuna kutafuna komanso kumwa madzi ambiri.
Pa gawo loyamba la chithandizo, mlingo uyenera kukhala 0,85g. 1 nthawi patsiku kapena 0.5g. 1-2 patsiku. Pang'onopang'ono onjezerani mlingo mpaka 3g. patsiku.
Zofunika! Kwa odwala okalamba, chizolowezi cha tsiku ndi tsiku sayenera kupitirira 1g. Chifukwa cha chiwopsezo chachikulu cha lactic acidosis, ndi ma metabolic amphamvu a metabolic, mlingo uyenera kuchepetsedwa.
Malangizo apadera ogwiritsa ntchito
Malangizo: munthawi ya chithandizo, muyenera kuwongolera matenda a impso. Kamodzi miyezi isanu ndi umodzi komanso chitukuko cha myalgia, ndikofunikira kudziwa kuchuluka kwa lactate mu plasma.
Formetin angagwiritsidwe ntchito limodzi ndi zotumphukira za sulfonylurea. Potere, kuyang'anira mosamala kuchuluka kwa shuga m'magazi kumafunika.
Formetin panthawi ya monotherapy sizikhudza kuthekera kugwira ntchito ndi maginito ovuta komanso kuyendetsa magalimoto. Ngati mankhwalawa akuphatikizidwa ndi mankhwala ena a hypoglycemic, chitukuko cha hypoglycemia chimatheka, momwemo osatha kuyendetsa galimoto komanso kugwira ntchito ndi maumboni ovuta omwe amafunikira chidwi chachikulu.
Zotsatira zoyipa
Kuchokera m'mimba:
- kulawa kwazitsulo
- kusanza, kusanza,
- chisawawa, kutsekula m'mimba,
- kusowa kwa chakudya
- kupweteka kwam'mimba.
Kuchokera ku ziwalo za hemopoietic nthawi zina zimachitika ndi kuchepa kwa magazi m'thupi.
About metabolism:
- Kufuna kusiya kwa mankhwalawa, lactic acidosis ndiyosowa,
- ndi chithandizo cha nthawi yayitali, hypovitaminosis B12 imayamba.
Dongosolo la endocrine pamlingo wokwanira lingayankhe ndi hypoglycemia.
Mawonekedwe a mziwopsezo: zotupa pakhungu.
Kuchita ndi mankhwala ena
Hypoglycemic mphamvu ya metformin imatha kulimbikitsidwa ikagwiritsidwa ntchito pamodzi:
- insulin
- zochokera sulfonylurea,
- oxytetracycline
- acarbose,
- mankhwala osapweteka a antiidal
- cyclophosphamide
- angiotensin otembenuza enzyme zoletsa,
- monoamine oxidase zoletsa
- β-blockers
- zotumphukira za clofibrate.
Kutsika kwa hypoglycemic zotsatira za metformin kumawonedwa pogwiritsa ntchito munthawi yomweyo:
- "Loop" ndi thiazide okodzetsa,
- kulera kwamlomo
- glucocorticosteroids,
- glucagon
- epinephrine
- phenothiazine zotumphukira,
- amphanomachul
- nicotinic acid zotumphukira,
- mahomoni a chithokomiro.
Contraindication
Simungatenge formin ndi:
- kuvulala kwambiri aimpso,
- matenda ashuga ketoacidosis, precoma, chikomokere,
- kupuma komanso kulephera kwa mtima,
- kusowa kwamadzi
- pachimake ubongo
- uchidakwa wambiri ndi zina zomwe zimapangitsa kuti lactic acidosis ikhale,
- pa mimba ndi kuyamwa,
- Hypersensitivity pamagawo a mankhwala,
- kuvulala komanso kuchitapo kanthu mochita opaleshoni yayikulu,
- matenda opatsirana opatsirana
- kuledzera kwa pachimake,
- lactic acidosis.
Langizo lomwe likutsatila likuti kugwiritsidwa ntchito kwa Formetin sikuyenera kutsogoleredwa ndi maphunziro a radiology ndi radioisotope ndikumayambitsa chinthu chomwe chili ndi ayodini mkati mwa masiku awiri.
Forethine sikulimbikitsidwa kuti igwiritsidwe ntchito ndi anthu opitilira 60 omwe amagwira ntchito zolimbitsa thupi. Ngati lamulo ili silikusungidwa, odwalawa amatha kukhala ndi lactic acidosis.
Zomwe malangizo osokoneza bongo amakamba
Malangizo a mankhwala a Formetin amachenjeza kuti ndi mankhwala osokoneza bongo, pali mwayi wokhala ndi lactic acidosis yokhala ndi zotsatira zakupha. Zomwe zimayambitsa vutoli zimatha kukhala kudzikundikira kwa mankhwala m'thupi chifukwa chazovuta aimpso.
Zizindikiro zotsatirazi ndizizindikiro zazikulu za lactic acidosis:
- Kusanza, kusanza.
- Kutsegula m'mimba, kupweteka kwam'mimba.
- Kufooka, hypothermia.
- Chizungulire
- Zowawa.
- Reflex bradyarrhythmia.
- Kutsitsa magazi.
- Kusokonezeka kwa chikumbumtima komanso kukula kwa chikomokere
Ngati wodwala ali ndi zizindikiro zoyambirira za lactic acidosis, Fomu liyenera kupatulidwa munjira zochiritsira, wodwalayo amayenera kupita kuchipatala komwe dokotala amatha kudziwa kuchuluka kwa lactate ndikupanga matenda osatsimikizika.
Njira yothandiza kwambiri yochotsa metformin ndi lactate kuchokera mthupi ndi hemodialysis, limodzi ndi chithandizo chamankhwala.
Fomu - yosungirako, mtengo
Alumali moyo wa mankhwalawa ndi miyezi 24, pambuyo pake Formetin singagwiritsidwe ntchito. Mankhwalawa ndi a mndandanda B. Uyenera kusungidwa pamalo amdima osavomerezeka kwa ana pamtunda wa osaposa 25 ° C.
Kutulutsa mawonekedwe - mapiritsi a 850 mg. 60 zidutswa.
Kutulutsa mawonekedwe - mapiritsi 1gr. 60 zidutswa.
Ma analogi ena ndi okwera mtengo kwambiri.
Oral hypoglycemic mankhwala
Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD
Mapiritsi yoyera, yozungulira, yosalala, yokhala ndi bevel ndi notch.
| 1 tabu | |
| metformin hydrochloride | 0,5 g |
Omwe amathandizira: povidone (sing'anga yamphamvu molekyulu polyvinylpyrrolidone, povidone K-30) - 0,017 g, croscarmellose sodium (primellose) - 0,008 g, magnesium stearate - 0,005 g.
Ma PC 10 - matumba a matuza (6) - mapaketi a makatoni
Mapiritsi yoyera, yozungulira, yosalala, yokhala ndi bevel ndi notch.
| 1 tabu | |
| metformin hydrochloride | 0,5 g |
Omwe amathandizira: povidone (sing'anga yamphamvu molekyulu polyvinylpyrrolidone, povidone K-30) - 0,017 g, croscarmellose sodium (primellose) - 0,008 g, magnesium stearate - 0,005 g.
Ma PC 10 - matumba a matuza (6) - mapaketi a makatoni.
Mapiritsi yoyera, chowulungika, biconvex, yokhala ndi notch mbali imodzi.
| 1 tabu | |
| metformin hydrochloride | 0,85 g |
Omwe amathandizira: povidone (sing'anga yamphamvu molekyulu polyvinylpyrrolidone, povidone K-30) - 0,029 g, croscarmellose sodium (primellose) - 0.0136 g, magnesium stearate - 0,0084 g.
Ma PC 10 - matumba a matuza (6) - mapaketi a makatoni.
Mapiritsi yoyera, chowulungika, biconvex, yokhala ndi notch mbali imodzi.
| 1 tabu | |
| metformin hydrochloride | 0,85 g |
Omwe amathandizira: povidone (sing'anga yamphamvu molekyulu polyvinylpyrrolidone, povidone K-30) - 0,029 g, croscarmellose sodium (primellose) - 0.0136 g, magnesium stearate - 0,0084 g.
Ma PC 10 - matumba a matuza (6) - mapaketi a makatoni.
Mapiritsi yoyera, chowulungika, biconvex, yokhala ndi notch mbali imodzi.
| 1 tabu | |
| metformin hydrochloride | 1 g |
Omwe amathandizira: povidone (sing'anga yamphamvu molekyulu polyvinylpyrrolidone, povidone K-30) - 0,034 g, croscarmellose sodium (primellose) - 0,016 g, magnesium stearate - 0,01 g.
Ma PC 10 - matumba a matuza (6) - mapaketi a makatoni.
Mapiritsi yoyera, chowulungika, biconvex, yokhala ndi notch mbali imodzi.
| 1 tabu | |
| metformin hydrochloride | 1 g |
Omwe amathandizira: povidone (sing'anga yamphamvu molekyulu polyvinylpyrrolidone, povidone K-30) - 0,034 g, croscarmellose sodium (primellose) - 0,016 g, magnesium stearate - 0,01 g.
Ma PC 10 - matumba a matuza (6) - mapaketi a makatoni.
Zotsatira za pharmacological
Oral hypoglycemic mankhwala ochokera pagulu la Biguanide. Amalepheretsa gluconeogeneis m'chiwindi, amachepetsa mayamwidwe m'matumbo, imathandizira kugwiritsidwa ntchito kwa glucose, komanso imakulitsa chidwi cha minofu kuti insulini. Sichikhudzanso kubisika kwa insulin ndi ma β-cell a kapamba, samayambitsa kukhudzika kwa hypoglycemic.
Lowers triglycerides ndi LDL.
Imakhazikika kapena kuchepetsa thupi.
Ili ndi fibrinolytic mwina chifukwa chokakamira minofu ya plasminogen activator inhibitor.
Pharmacokinetics
Pambuyo pakukonzekera pakamwa, metformin imatengedwa kuchokera m'mimba. Bioavailability mutatenga muyezo mlingo 50-60%. Cmax pambuyo pakamwa makonzedwe zimatheka pambuyo 2,5 maola.
Sizikugwirizana ndi mapuloteni a plasma. Amadziunjikira mu ndulu zakumaso, minofu, chiwindi, ndi impso.
Amatulutsidwa popanda mkodzo. T1 / 2 ndi maola 1.5-4.5.
Pharmacokinetics mu milandu yapadera yamankhwala
Ndi matenda aimpso, kuwonongeka kwa mankhwalawa ndikotheka.
- Type 2 shuga mellitus ndi kusachita bwino kwa mankhwala othandizira (makamaka odwala omwe ali ndi kunenepa kwambiri).
Contraindication
- matenda ashuga ketoacidosis, matenda a shuga, chikomokere,
- Zowopsa zaimpso,
- machitidwe omwe angathandizire kukulitsa lactic acidosis, kuphatikiza mtima ndi kupuma kulephera, pachimake gawo la kulowerera m'mitsempha, ngozi ya mtima pachimake, kuchepa magazi, uchidakwa,
- chiwindi ntchito,
- poyizoni mowa,
- matenda opatsirana opatsirana,
- lactic acidosis (kuphatikizapo mbiri),
- opaleshoni yayikulu ndikuvulazidwa (mu izi, chithandizo cha insulin chimasonyezedwa),
- gwiritsani ntchito pasanathe masiku awiri asanafike komanso masiku awiri mutapanga maphunziro a radioisotope kapena X-ray ndikukhazikitsa ma iodine okhala ndi zosiyana pakati,
- kutsatira zakudya zochepa zopatsa mphamvu (zosakwana 1000 cal / tsiku),
- mkaka wa m'mawere (yoyamwitsa),
- Hypersensitivity ku zigawo za mankhwala.
Sitikulimbikitsidwa kugwiritsa ntchito mankhwalawa odwala omwe ali ndi zaka zopitilira 60 omwe amagwira ntchito zolimbitsa thupi, chifukwa chowonjezera chiopsezo cha lactic acidosis.
Khazikikani payekhapayekha, poganizira kuchuluka kwa shuga m'magazi.
Mlingo woyambirira ndi 500 mg 1-2 nthawi / tsiku kapena 850 mg 1 nthawi / tsiku. Pambuyo pake, pang'onopang'ono (nthawi 1 pa sabata), mlingo umakulitsidwa ku 2-3 g / tsiku. Pazipita tsiku mlingo 3 g.
At odwala okalamba tsiku mlingo sayenera upambana 1 g.
Chifukwa cha chiwopsezo cha lactic acidosis, popereka metformin kwa odwala omwe ali ndi vuto lalikulu la metabolic, mlingo uyenera kuchepetsedwa.
Mapiritsi ayenera kumwedwa nthawi yakudya kapena itatha, osafuna kutafuna komanso kumwa madzi ambiri.
Kuchokera m'mimba: kusanza, kusanza, "zachitsulo" mkamwa, kusowa kudya, kutsegula m'mimba, kusilira, kupweteka kwam'mimba.
Kuchokera kumbali ya kagayidwe: kawirikawiri - lactic acidosis (imafuna kuleka kwamankhwala), pogwiritsa ntchito nthawi yayitali - B12 hypovitaminosis (malabsorption).
Kuchokera ku hemopoietic system: Nthawi zina - megaloblastic anemia.
Kuchokera ku endocrine system: hypoglycemia (mukamagwiritsa ntchito mankhwala osayenera).
Zotsatira zoyipa: zotupa pakhungu.
Bongo
Zizindikiro lactic acidosis imayamba. Zomwe zimayambitsa kukula kwa lactic acidosis amathanso kukhala cumulation wa mankhwalawa chifukwa cha kuwonongeka kwa aimpso.
Zizindikiro zoyambirira za lactic acidosis ndizofooka wamba, nseru, kusanza, kuchepa thupi, kupweteka kwam'mimba, kupweteka kwa minofu, kutsitsa magazi, Reflex bradyarrhythmia, mtsogolomo zitha kukulitsa kupuma, chizungulire, chikumbumtima chodwala komanso kukula kwa chikomokere.
Chithandizo: ngati pali zizindikiro za lactic acidosis, chithandizo ndi metformin chiyenera kuyimitsidwa nthawi yomweyo, wodwalayo amapita kuchipatala ndipo atatsimikiza kuchuluka kwa lactate, atsimikizireni matendawa. Hemodialysis imathandiza kwambiri pochotsa lactate ndi metformin m'thupi. Ngati ndi kotheka, chitani mankhwala othandizira.
Kuyanjana kwa mankhwala osokoneza bongo
Pogwiritsa ntchito munthawi yomweyo ndi sulfonylurea zotumphukira, ma acarbose, insulin, NSAIDs, ma inhibitors a MAO, oxytetracycline, ma inhibitors a ACE, clofibrate zotumphukira, cyclophosphamide ndi beta-blockers, ndizotheka kuwonjezera mphamvu ya hypoglycemic ya metformin.
Pogwiritsa ntchito munthawi yomweyo ndi GCS, kulera kwapakamwa, epinephrine (adrenaline), sympathomimetics, glucagon, mahomoni a chithokomiro, thiazide ndi "loop" okodzetsa, phenothiazine zotumphukira ndi nicotinic acid, kuchepa kwa mphamvu ya hypoglycemic ya metformin ndikotheka.
Cimetidine amachepetsa kuchotsedwa kwa metformin, chifukwa chomwe chiopsezo cha lactic acidosis chikuwonjezeka.
Metformin itha kufooketsa mphamvu ya ma anticoagulants (zotumphukira za coumarin).
Ndi munthawi yomweyo makonzedwe ndi Mowa, kukula kwa lactic acidosis ndikotheka.
Ndi munthawi yomweyo kugwiritsa ntchito nifedipine kumawonjezera mayamwidwe a metformin ndi Cmax, kumachepetsa kuchotsa chimbudzi.
Mankhwala a Cationic (amlodipine, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren, vancomycin) omwe amatulutsidwa m'mapikisano olimbana ndi machitidwe oyendetsa ma tubular ndipo, akakhala ndi chithandizo chambiri, amatha kuonjezera Cmax ndi 60%.
Malangizo apadera
Munthawi yogwiritsira ntchito mankhwalawa, zizindikiro za impso ziyenera kuyang'aniridwa. Osachepera 2 pachaka, komanso maonekedwe a myalgia, zomwe zimakhala mu plasma ziyenera kutsimikiziridwa.
Ndikotheka kugwiritsa ntchito Formetin kuphatikiza zomwe zimachokera ku sulfonylurea, makamaka kuyang'anira kuchuluka kwa shuga m'magazi ndikofunikira.
Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu
Mukamagwiritsidwa ntchito ngati monotherapy, mankhwalawa sasokoneza luso loyendetsa magalimoto ndikugwira ntchito ndi zida.
Ndi kuphatikiza kwa Formetin ndi mankhwala ena a hypoglycemic (sulfonylurea derivatives, insulin), mikhalidwe ya hypoglycemic ingayambike momwe kuthekera kuyendetsa magalimoto ndi zochitika zina zoopsa zomwe zimafunikira chidwi chochulukirapo komanso kuthamanga kwa zochitika zama psychomotor.
Kutulutsa mafomu ndi kapangidwe kake
Pali piritsi lamankhwala. Mu katoni ikhoza kukhala ndi mapiritsi 30, 60 kapena 100. Mwanjira ya kuyimitsidwa ndi mitundu ina ya mankhwala, wothandizirayo samatulutsa.
The yogwira ndi metformin hydrochloride muyeso wa 500, 850 kapena 1000 mg. Zoonjezera zina za mankhwalawa ndi:
- sodium croscarmellose,
- magnesium wakuba,
- polyvinylpyrrolidone.
Pali piritsi lamankhwala. Mu katoni ikhoza kukhala ndi mapiritsi 30, 60 kapena 100. Mwanjira ya kuyimitsidwa ndi mitundu ina ya mankhwala, wothandizirayo samatulutsa.
Ndiwogwiritsa ntchito hypoglycemic wopangidwira kukwaniritsa zotsatirazi:
- kukulitsa kugwiritsa ntchito shuga,
- Kuchepetsa njira yopanga shuga yomwe imachitika m'chiwindi,
- kukulitsa chidwi cha minyewa pazotsatira za insulin (chifukwa chake, kuchuluka kwa shuga mumagazi),
- kulemera masanjidwewo
- chepetsa milingo yama lipoproteins otsika ndi triglycerides,
- chepetsa mayamwidwe a shuga opezeka m'matumbo.
Kuphatikiza apo, mankhwalawa sakukhudzanso kubisika kwa insulini mu kapamba ndipo sikuti kumabweretsa mayendedwe achilendo a hypoglycemic.
Zaumoyo Live mpaka 120. Metformin. (03/20/2016)
Mapiritsi ochepetsa shuga a Metformin
Momwe mungatengere FORMETINE
Mlingo wa mankhwalawa amasankhidwa payekhapayekha, poganizira zomwe zimayimira shuga m'magazi a wodwala. Yambani ndi kuchuluka kwa 500 mg 1-2 kawiri pa tsiku kapena kugwiritsa ntchito kamodzi kwa 850 mg ya mankhwala.
Pang'onopang'ono, mlingo umakulitsidwa kwa 2-3 g patsiku. Kuchuluka kwa mankhwalawa sikuyenera kupitirira 3 g patsiku.
Mlingo wa mankhwalawa amasankhidwa payekhapayekha, poganizira zomwe zimayimira shuga m'magazi a wodwala.
Musanadye kapena musanadye
Kulandila kwa Formetin kutha kuchitika onse mukatha kudya, komanso mukamadya. Mankhwala amaloledwa kumwa ndi madzi.
Ndikulimbikitsidwa kugwiritsa ntchito mankhwalawa madzulo, omwe kupewa mavuto oyipa m'mimba. Mukamwa mankhwalawa 2 pa tsiku, mankhwalawa amatengedwa m'mawa komanso madzulo.
Matumbo
Ndi kukula kwa zovuta zomwe zimakhudza dongosolo logaya chakudya, wodwalayo amayamba kudandaula za zotsatirazi:
- kusowa kwa chakudya
- kusasangalala m'mimba
- nseru
- chisangalalo
- kukoma koyipa mkamwa
- kutsegula m'mimba
- kusanza.
Kusanza ndi mseru ndi zina mwazotsatira zoyipa za mankhwalawa m'mimba.
Hematopoietic ziwalo
Nthawi zina, anthu omwe amagwiritsa ntchito mankhwalawa amakhala ndi vuto la kuchepa kwa magazi m'thupi. Pankhaniyi, kuphwanya kukuwoneka ndi zizindikiro:
- kumva kuzizira
- phokoso mokhumudwa
- kudya nyama,
- kufooka wamba
- paresthesias
- dzanzi la miyendo
- kusakhazikika.
Kuchita ndi mankhwala ena
Sikulimbikitsidwa kuphatikiza kugwiritsa ntchito fayilo imodzi ndi mitundu yotsatira.
- anticoagulants okhudzana ndi zotumphukira kuchokera ku coumarin - zovuta zamankhwala zimachepa,
- phenothiazine, mankhwala okodzetsa a mtundu wa thiazide, glucagon, njira zakulera zamkamwa - mphamvu ya gawo lomwe limagwiritsidwa ntchito ndi mankhwala limachepetsedwa,
- cimetidine - kuchotsedwa kwa metformin mthupi la wodwalayo,
- chlorpromazine - chiopsezo cha hyperglycemia chimawonjezeka,
- Danazole - mphamvu ya hyperglycemic imatheka,
- ACE inhibitors ndi MAO, zochokera ku clofibrate ndi NSAIDs - kuchuluka kwa mawonekedwe a Formetin.
Kuyenderana ndi mowa
Kugwiritsa ntchito zakumwa zokhala ndi zakumwa zoledzeretsa kumawonjezera chiopsezo cha lactic acidosis.
Muyenera kupewa kumwa mowa kuti muchepetse kukula kwa lactic acidosis.
Mankhwala akhoza m'malo ndi analogues.
Zida izi ndi:
- Glucophage - mankhwala ochepetsa hyperglycemia.
- Siofor - mankhwala omwe ali m'gulu la Biguanides. Imakhala ndi phindu pa metabolidi ya lipid ndikuchepetsa gluconeogeneis.
- Forin Long ndi mtundu wa mankhwala womwe amakhala ndi 500, 750, 850 kapena 1000 mg.
- Gliformin ndi mankhwala omwe cholinga chake ndi kuchepetsa kuchuluka kwa triglycerides ndi LDL. Mankhwala amatha kuchedwetsa gluconeogeneis.
- Metformin - mankhwala omwe ali ndi chiwalo chimodzi, omwe amapezeka mu 0,5 kapena 0,85 g.
- Bagomet ndi mankhwala a hypoglycemic omwe cholinga chake ndi pakamwa.
Siofor ndi Glukofazh kuchokera ku matenda ashuga komanso kuwonda
Matenda a shuga, metformin, masomphenya a shuga | Dr. Butchers
Umboni wa madotolo ndi odwala za Formetin
Arseny Vladimirov, endocrinologist wazaka 54, Moscow
Kugwiritsa ntchito kwa FORMETINE ndi chipulumutso kwa odwala omwe ali ndi kunenepa kwambiri chifukwa cha matenda ashuga. Chipangizocho chimasintha matenthedwe kuti tisanthe insulin, osapereka mphamvu pakadwala. Ubwino wina ndi mtengo wotsika mtengo.
Valentina Korneva, endocrinologist, wazaka 55, Novosibirsk
Mankhwalawa ndi othandiza. Ndimapereka mankhwala kwa odwala anga nthawi zambiri. Palibe amene adadandaula za zotsatira zoyipa. Ndipo mkhalidwewo ukukonzanso.
Victoria, wazaka 45, Volgograd
Mothandizidwa ndi Formine, ndimasunga kulemera, monga chifukwa cha matenda ashuga, adayamba kuchuluka. Mankhwalawa ndiokwera mtengo, akupezeka ku Russia. Ndimamwa mankhwalawa madzulo. Komabe, muyenera kutsatira zakudya, kupatula mbale ndi zinthu zomwe zili ndi zopatsa mphamvu.
Dmitry, wazaka 41, Yekaterinburg
Ndakhala ndikuchiza formethine nthawi yayitali, chifukwa Ndadwala matenda ashuga kwa zaka zoposa 15. Mankhwala amathandiza, osakhala ndi mavuto. Ndimamwa mankhwalawa 2 pa tsiku piritsi.
Maria, wazaka 56, Saratov
Ndakhala ndikuvutika ndi matenda ashuga pafupifupi zaka 5. Nthawi yonseyi, Gliformin adagwiritsa ntchito, zomwe adadokotala adamuuza. Mankhwalawa adathandizira, chifukwa chake ndimatha kuwagwiritsa ntchito mopitilira, koma ndikamapita kuchipatala adati palibe mankhwalawa.
Forethine adasankhidwa kuti alowe m'malo. Ndinkawopa kuti kusintha mankhwala kungandibweretsere mavuto ena, koma zidatha. Thupi linalekerera mankhwalawa bwino, motero ndikupitiliza kuigwiritsa ntchito.
Pakadali pano, anthu ochulukirapo akuvutika ndi matenda a shuga komanso kunenepa kwambiri kwamtundu wovuta. Pali mankhwala ambiri ochizira matenda awa. Chimodzi mwazomwezi ndi mankhwala akuti "Fomati". Pazokhudza machitidwe ake omwe takambirana m'nkhaniyi.
Kufotokozera kwa kapangidwe ndi mawonekedwe amasulidwe
Piritsi limodzi lili:
sing'anga yama cell molemera povidone
Formetin imapezeka m'matumba a blister a 100, 60 kapena 30.
Mtundu wa mapiritsiwo ndi woyera, ndipo mawonekedwewo amatengera muyeso wa chinthu chachikulu. Pa 500 mg, ali ndi mawonekedwe ozungulira mozungulira omwe amakhala ndi notch ndi chamfer. Komanso, kuchuluka kwa 1000 mg ndi 850 mg ndi "Fomu". Mapiritsi pamenepa ndi opanikizika komanso owondera. Ali ndi chiopsezo cha mbali imodzi.
Metformin ("Formethine") amachepetsa gluconeogeneis omwe amapezeka m'chiwindi, pomwe amatsikanso pakugulitsa kwake kwa glycogen.
Chida ichi chimathandizira kugwirizanitsa kuyamwa kwa glucose kuchokera m'matumbo, kumathandizira kupukusira kwa shuga kuchokera kuzinthu zoyendayenda.
Nthawi yomweyo, kuyankha kwamtundu wa insulin kumawonjezeka, osakhudza kupanga kwa gawo lawo la endocrine ndi kapamba ndi maselo a B, kupitilira zomwe zimachitika mu hypoglycemic, popeza kupanga izi sikuchitika.
Mankhwala "Formetin", ndemanga zomwe zimanena za kugwira ntchito kwake, amachepetsa cholesterol "yoyipa" ndi triglycerides m'mwazi. mkulu osachulukitsa lipoproteins nthawi imodzi imachulukanso ndi 20-30%.
Ndi chakudya chopanda tanthauzo, mankhwalawa "Formetin", malangizo ogwiritsira ntchito omwe afotokozedwa m'nkhaniyi, amathandizira kuchepetsa komanso / kapena kukhazikitsa kulemera kwa wodwalayo. Izi zimachitika chifukwa cha kukhathamiritsa kwa glucose munjira yopanda mpweya, komanso kuchepa kwa njala.
Komanso, njira ya plasminogen activation ya minofu imapangidwa pochita ndi inhibitor yake, ndipo pali kuthekera kwambiri.
Kupita
Mankhwala "Fomu" amagwiritsidwa ntchito pochiza matenda ena ake. Ndiye kuti pamaso pa matenda a shuga a mtundu wachiwiri, vuto la kunenepa kwambiri, pamene zakudya sizithandiza kusunga shuga wambiri, ngakhale limodzi ndi sulfonylurea. Chothandizanso ndi "Fomu" yochepetsa thupi.
Kutenga?
Dokotala amasankha kuchuluka kwa mankhwalawa kutengera kuchuluka kwa shuga m'magazi. Kukonzekera kwa pakamwa kuyenera kuchitika mukatha kudya, kumamwa madzi ambiri osaneneka piritsi kuti lingagwiritsidwe ntchito.
Monga tanenera kale pamwambapa, mulingo wa mankhwalawo umaperekedwa malinga ndi kuchuluka kwa shuga m'magazi. Zimayamba ndi kuchuluka kwa 0,5 g kapena 0,85 g patsiku. Patatha masiku awiri chiyambireni kumwa mankhwalawa, mawonekedwe a metformin m'magazi amawonedwa.
Ngati ndi kotheka, mutha kuwonjezera pang'onopang'ono mlingowo. Ndi ofanana ndi magalamu atatu.
Popeza kakulidwe ka lactic acidosis nthawi zambiri kumawonedwa mwa anthu okalamba, kuchuluka kwa mlingo wa tsiku ndi tsiku ndi 1 g kwa iwo. Komanso, kuchuluka kwa mankhwalawa kumachepetsedwa pakusokoneza kagayidwe kachakudya, kupewa kuyanjana, komwe kumawonetsedwa ngati zotupa pakhungu, ndi zotsatirapo zina zoyipa zomwe zingakambidwe pansipa.
Zotsatira zoyipa
Kupezeka kwa zizindikiro zosasangalatsa ngati "chitsulo" pakamwa, kusanza, nseru, kutsegula m'mimba, mpweya, kusowa kudya kumafunika kusiya kugwiritsa ntchito mankhwalawa ndikulumikizana ndi katswiri.
Kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumayambitsa kuphwanya kapena kumaliza kuyamwa kwa vitamini B12, komwe kumapangitsa kuti thupi lizikundana kwambiri, zomwe zimayambitsa hypovitaminosis. Nthawi zina, zosiyana zimayamba - kuchepa kwa magazi m'thupi la B12. Ndi kumwa kolakwika, hypoglycemia ndiyotheka. Thupi lawo siligwirizana chifukwa cha totupa pakhungu limathanso kuchitika.
Chifukwa chake, mankhwalawa "Fomu", mawunikidwe a momwe amagwiritsidwira ntchito, ali osiyana, akuyenera kutumizidwa ndi adokotala okha.
Njira zofunikira zimatsimikiziridwa ndi kuphatikizika kwa kuphatikizika kwa chinthu chachikulu "Fomu" m'thupi ndi zotsatira zake.
Pofuna kupewa kuchulukana kwa metformin komanso kupewa lactic acidosis, ndikofunikira kuyang'anitsitsa chizindikiro cha ntchito ya impso ndikuyesera kuti mupeze kuchuluka kwa lactic acid mthupi pafupifupi kawiri pachaka. Komanso, ndikuwoneka ngati ululu m'misempha, kuyesedwa kwachiwiri kuyenera kuchitidwa.
Zotsatira za mankhwalawa pakuwongolera njira ndi magalimoto oyendetsa
Pankhaniyi, palinso ma nuances ena. Mphamvu ya "Fomu" pa kuthekera koongolera kayendedwe ndimayendedwe zimachitika pokhapokha ngati imagwiritsidwa ntchito limodzi ndi mankhwala omwe amakhudza magwiridwe antchito, amafunika mayankho achangu ndikuwonjezera chidwi. Izi ndizofunikira kudziwa.
Gwiritsani ntchito poyamwitsa ndi pakati
Mankhwala "Fomu", malangizo ogwiritsira ntchito omwe akufotokozedwa mulemba ili, ali ndi gawo lowonekera kwa mwana wosabadwayo "B" malinga ndi FDA. Pa nthawi yoyembekezera, mankhwalawa amatha kumwa. Komabe, kugwiritsidwa ntchito kwake kungakhale muzochitika zina.
Moona, pamene zotsatira zoyembekezeredwa kuchokera ku mankhwalawa zidzaposa kukhalapo kwa chiwopsezo kwa mwana wosabadwayo. Kafukufuku wina komanso wapadera wogwiritsidwa ntchito ngati mankhwalawa monga "Fomu" sanachitidwe panthawi yapakati. Pa nthawi ya chithandizo ayenera kusiya kuyamwitsa.
Mulimonsemo, muyenera kufunsa dokotala woyenera.
"Fomu": analogues
Pali ndalama zambiri zamtunduwu. Zofanizira za "Fomu" ndizokonzekera zomwe zimapangidwa monga gawo lalikulu la metformin hydrochloride.
Mwachitsanzo ndi mankhwala a opanga aku Russia: Vero-Metformin, Glformin, Metformin, Metformin Richter, ndi ena akunja - Glyukofag, Glyukofazh ndi Glyukofazh Long (France), Langerin "(Slovakia)," Metfogamma "yokhala ndi mitundu yosiyanasiyana ya yogwira 0.100, 0.500 ndi 0,850 g (Germany).
Mtengo wapakati wa mankhwalawa "Formetin" umayikidwa kutengera mlingo: kuchokera ma ruble 59. pachimake pa 0,5 g, ma ruble 133. kwa 0,85 g ndi 232 ma ruble. 1 g.
