Zabodza zokhudza cholesterol ndi ma statins: nkhani zaposachedwa ndi malingaliro a asayansi
Kwa zaka zambiri osavutika ndi CHOLESTEROL?
Mutu wa Bungwe: “Mudzadabwa momwe zimakhalira zosavuta kuchepetsa mafuta m'thupi mwakumwa tsiku lililonse.
Ubwino wazakudya zam'madzi zam'madzi ndizodziwika kale. Tiyerekeze kuti nyengo yathu sikhala gawo lalikulu la chakudyacho, koma mawonekedwe awo amakoma amadziwika ndipo ali ndi mafani ambiri. Ponena za zakudya zam'nyanja, sizipweteka kudziwa ngati ndizothandiza kapena zovulaza kwa anthu omwe ali ndi matenda osiyanasiyana. Mwachitsanzo, funso loti momwe cholesterol ndi nsomba zam'madzi zimaphatikizidwira zimakhalabe zotseguka mpaka pano. Izi zili choncho mwina chifukwa cha mitundu yayikulu ya nsomba zam'madzi ndi kusiyana kwawo kapangidwe kake. Tiyeni tiyese kuzindikira.
Kafukufuku wasonyeza kuti nsomba zina zam'madzi zimakhala ndi cholesterol yambiri kuposa nyama. Palinso nsomba zam'nyanja momwe sizikupezeka. Chifukwa chake, tikupangira kuti muphunzire gome ili.
Zogulitsa, 100 g | Cholesterol, mg |
Maussels | 64 |
Far Shrimp Wakummawa | 160 |
Shirimpu waku Antarctic | 210 |
Ankhandwe | 87 |
Spiny lobster | 90 |
Oysters | 170 |
Scallops | 53 |
Cuttlefish | 275 |
Lobster | 85 |
Squid | 85 |
Caviar wakuda | 300-460 |
Red caviar | 310 |
Poyerekeza. 100 g ya ng'ombe ya chiwindi ili ndi 270 mg wa cholesterol, 100 g wa mazira - 1510 mg, 100 g batala - 150 mg. Mungaone kuti cholesterol zomwe zili munyanja zam'madzi ndizofala kwambiri. Ngakhale nsomba zamchere zamchere zimasiyana kwambiri ndi kuchuluka kwa cholesterol yomwe ali nayo.
Nsomba, 100 g | Cholesterol, mg |
Codfish | 50 |
Hake | 70 |
Haddock | 40 |
Pollock | 50 |
Sprat | 87 |
Hering | 45-90 (kutengera ndi zamafuta) |
Halibut | 60 |
Salimoni yapinki | 60 |
Chum | 80 |
Salimoni | 70 |
Monga mukuwonera, mumapezeka ma cholesterol m'madzi am'madzi ndi nsomba, ndipo nthawi zina pamakhala zochuluka zokwanira. Zikuwoneka kuti pankhaniyi, zakudya zam'madzi zambiri zimayenera kukhala zophatikizika kwa anthu omwe ali ndi cholesterol yayikulu. Koma, mwamwayi, izi siziri choncho. Zakudya zam'madzi zimakhala ndi zina zamankhwala zomwe zimakupatsani mwayi kudya zambiri za izo ngakhale ndi mafuta ambiri.
Katundu katundu
Phindu ndi zoopsa za zakudya zam'nyanja zina ndizambiri zomwe nthawi zina zimatsimikiziridwa, ndipo nthawi zina zimatsutsidwa ndi asayansi.
- Shirimp Mpaka posachedwa, shrimp idkaganiziridwa kuti ndi yoyipa ndi cholesterol yayikulu. Shrimp nthawi zambiri amatsogolera cholesterol poyerekeza ndi zina zam'madzi. Koma osati zophweka. Kafukufuku waposachedwa ndi asayansi aku Australia adzetsa zotsatira zosayembekezeka. Malinga ndi ofufuza aku Australia, shrimp sikuti imangokhala zovulaza zokha, komanso imathandizira kuchotsa cholesterol m'thupi.
Chowonadi ndi chakuti antioxidant wamphamvu, astaxanthin, adapezeka mu shrimp, yemwe ali wamphamvu kwambiri nthawi 10 kuposa ma antioxidants omwe amapezeka mu zipatso ndi zipatso, ndipo nthawi zambiri mwamphamvu kwambiri kuposa vitamini E Astaxanthin wodziwika bwino amateteza maselo amthupi ku ukalamba, pazovuta ngakhale kuchokera ku radiation. Zimakhala ndi phindu pamtima wamatenda, kupewa chiopsezo cha kugwidwa ndi matenda a mtima.
Chifukwa cha kuchuluka kwambiri kwa mapuloteni, ma crustaceans awa amapatsa thupi kuchuluka kwakukulu kwama amino acid. Kuchokera pazonsezi pamwambapa, titha kuganiza kuti malingaliro okhudzana ndi zoopsa za nsomba zam'nyanjayi zomwe si zoona.
- Scallops. Izi mollusks zimawonedwa kuti ndizopindulitsa kwambiri kwa anthu omwe ali ndi cholesterol yambiri. Ndi ma calorie otsika, okhala ndi magnesium, chitsulo, ayodini, mkuwa, zinc, phosphorous, cobalt, manganese, komanso ma mulactitamin ovuta kwambiri ndi ma omega acids.
Ma Scallops amathandizira kuchepa kwa mafuta m'thupi, kumawonjezera mamvekedwe amthupi, kusintha ntchito ya endocrine, mantha amtima ndi mtima. Kudya iwo kumawerengedwa kuti ndi njira yabwino yotsatsira chitukuko cha atherosulinosis.
Mu mankhwala azitsamba, cholesterol ilibe konse. Ili ndiye msoka wodziwika bwino wam'madzi kapena kelp. Msoka wam'madziwu ndi malo osungiramo zinthu zothandiza komanso kuchiritsa. Zapangidwe zamadzi am'nyanja:
- mapuloteni - 13%,
- mafuta - 2%,
- chakudya - 59%,
- mchere wamchere - 3%.
Laminaria ndi wolemera mu mankhwala awa: bromine, ayodini, manganese, chitsulo, magnesium, nthaka, sulfure, phosphorous, potaziyamu, cobalt, nayitrogeni, etc. Muli mavitamini ambiri am'nyanja zamchere: A, B1, B2, B12, C, D, E. Mwakuyerekeza, malinga ndi asayansi, pali mavitamini 40, michere ndi micro yayikulu michere yam'madzi. Kapangidwe ka seaweed ndikosiyana, ndipo chifukwa cha izi, zopindulitsa zake ndizambiri.
- Kale kale mumakhala ma antioxidants amphamvu, omwe amathandizanso kupangitsanso thupi komanso kutalikitsa moyo. Laminaria imalepheretsa kukula kwa atherosulinosis.
- Zimalepheretsa kufalikira kwa cholesterol. Komanso, imasungunula ndikuyichotsa m'thupi.
- Zimagwira ntchito yofunika kwambiri popewa khansa.
- Zimalepheretsa magazi kuwunika popanga magazi.
- Imalimbitsa chitetezo chathupi komanso imasintha mawu.
Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.
Kugwiritsa ntchito njira zopewera kusoka kwamadzi mu timipuni tiwiri zokha patsiku kumathandizira kuti thupi likhale losangalatsa.
Zakudya zam'nyanja zomwe zimatha kudyedwa ndi cholesterol yayikulu
Poyamba, sikuti ndizotheka zokha, komanso ndikofunikira kudya nsomba zam'madzi zopanda cholesterol, zomwe zimatchedwa seaweed. Ndi gawo la zakudya zambiri kutsitsa cholesterol yamagazi.
Kwa nsomba zam'nyanja zina ndi nsomba, pali malingaliro ena.
- Nthawi zambiri, ndipo mothandizidwa ndi thupi, mumatha kudya zakudya zam'madzi ndi nsomba zomwe zimakhala ndi mafuta pang'ono. Awa ndi makoko, nkhanu, mussels, squid, cod, haddock, etc.
- Pocheperako nthawi zambiri mumatha kudzichitira nokha shrimp ndi oyster.
- Pazochitika zapadera, koma osowa, mutha kugula caviar pang'ono.
Ndi cholesterol, mutha kudya nsomba zam'madzi, koma mukungofunikira kudziwa muyeso, ndiye kuti mutha kupeza zabwino zonse zomwe nsomba zam'nyanja zimapereka osavulaza thupi lanu.
Zabodza zokhudza cholesterol ndi ma statins: nkhani zaposachedwa ndi malingaliro a asayansi
Pakadali pano, matenda a mtima ndi mtima, makamaka atherosulinosis, omwe amachititsa zovuta zambiri, ndi ambiquitous. Madokotala amadziwa zonse zokhudza cholesterol.
Komabe, anthu ambiri sakudziwa chifukwa chake akupangidwira, momwe angapewerere chitukuko chake komanso "cholesterol" yodabwitsa bwanji.
Chifukwa chake, cholesterol ndi chinthu chopangidwa m'maselo a chiwindi otchedwa hepatocytes. Ndi gawo la phospholipids, lomwe limapanga membrane wa plasma wama cell minofu. Imalowa mthupi la munthu limodzi ndi zopangidwa ndi nyama, koma izi zimapanga 20% yokha yonse - zotsalazo zimapangidwa ndi thupi lokha. Cholesterol amatanthauza ma subsidies a lipids - ma lipophilic alcohols - chifukwa chake asayansi akunena za cholesterol monga "cholesterol." Mu Chirasha, matchulidwe onsewa ndi olondola.
Cholesterol ndiye poyambira zinthu zambiri zamitundu mitundu. Vitamini D3 imapangidwa kuchokera kwa iyo ndipo kuwala kwa ultraviolet pakhungu. Ma mahomoni ogonana - amuna ndi akazi - amapangidwa mu cortical chinthu cha adrenal glands, ndipo amaphatikiza ndi nthenda yotentha, ndi ma asidi a bile - opangidwa ndi hepatocytes - amaphatikizana ndi cholesterol yotengera cholanic acid yamagulu a hydroxyl.
Chifukwa cha kuchuluka kwa mowa wa lipophilic mu membrane wa cell, katundu wake amadalira mwachindunji. Ngati ndi kotheka, kukhazikika kwa nembanemba kumasinthidwa mbali ina, kupatsanso madzi ena mosasintha. Katundu yemweyo amateteza maselo ofiira magazi kuti asalowe m'matumbo a hemolytic.
M'maselo amunthu, pali jini yomwe imatha kuwongolera kuchuluka kwa cholesterol ndikuwongolera kukula kwa shuga.
Kusintha kwa jini la APOE kumawonjezera chiopsezo cha matenda ashuga, koma kuchita zinthu zina limodzi ndi cholesterol kumachepetsa mwayi wamatenda oyamba.
Mitundu ya ma lipophilic alcohols
Popeza ma cholesterol ndi ma hydrophobic mankhwala, samasungunuka m'madzi, motero sangathe kuzungulira magazi ake okha.
Kuti muchite izi, zimagwirizana ndi mamolekyulu ena otchedwa alipoproteins.
Cholesterol chikaphatikizika kwa iwo, chinthucho chimatchedwa lipoprotein.
Ndi njira iyi yokha yomwe imatha kuyendetsa magazi kulowa m'magazi popanda kuopsa kwa kutsekeka kwamafuta kwa duct yotchedwa embolism.
Mapuloteni a Transporter ali ndi njira zosiyanasiyana zomangira kolesterol, kuchuluka ndi kuchuluka kwa mphamvu ya madzi sungunuka. Kutengera izi, malinga ndi asayansi ndi madokotala za cholesterol, amagawidwa m'magulu otsatirawa:
- Ma lipoproteins apamwamba kwambiri - mwa anthu amadziwikanso kuti "cholesterol wabwino", yemwe adatchulidwa chifukwa cha anti-atherogenic katundu wake. Zimatsimikiziridwa kuti amatenga cholesterol yowonjezereka m'maselo ndikupereka kwa chiwindi kuti apangidwe ndi bile acid, komanso kwa tiziwalo timene timatulutsa m'mimba, timayeso ndi thumba losunga mazira kuti tipeze mahomoni ogonana mopitilira muyeso. Koma izi zimachitika pokhapokha ndi kuchuluka kwa HDL, komwe kumatheka mwa kudya zakudya zopatsa thanzi (masamba, zipatso, nyama yopanda mphamvu, chimanga, ndi zina zambiri) komanso kupsinjika mokwanira. Komanso, zinthuzi zimakhala ndi mphamvu ya antioxidant, ndiye kuti, zimamangirira ma free radicals mu khoma lowonongeka la cell ndikuziteteza kuti zisakumane ndi kuchuluka kwa zinthu zomwe zimapangitsa kuti pakhale oxidation,
- Kutsika kwambiri kwa lipoproteins - amapangidwa mu chiwindi kuchokera ku mankhwala amkati. Pambuyo pa hydrolysis yawo, glycerol imapangidwa - imodzi mwazinthu zamagetsi zomwe zimagwidwa ndi minofu minofu. Kenako amasintha kukhala ma lipoproteins apakatikati,
- Ma lipoproteins otsika kwambiri - ndiye chinthu chomaliza mwa kutembenuka kwa LPP. Zolemba zawo zapamwamba zimakwiyitsa chitukuko cha atherosulinosis, chifukwa chake dzina "cholesterol yoyipa" ndilovomerezeka,
Kuphatikiza apo, ma chylomicrons, omwe ndiopambana kwambiri pazigawo zonse, amadziwika kuti ndi cholesterol. Amapangidwa m'matumbo ang'onoang'ono.
Chifukwa cha kuchuluka kwawo, ma chylomicrons sangathenso kulowa ma capillaries, chifukwa chake amakakamizidwa kulowa ma lymph node kenako kulowa m'chiwindi ndi magazi.
Zowongolera Zowopsa
Ma lipoprotein onse ayenera kukhala okhazikika bwino pakupanga ziwalo ndi machitidwe, kupatula ma pathologies onse ndi zilema.
Kuchuluka kwa cholesterol yathunthu mwa munthu wathanzi kuyenera kusiyana kuchokera pa 4 mpaka 5 mmol / l. Mwa anthu omwe ali ndi mbiri yamatenda aliwonse osachiritsika, manambalawa amachepetsedwa mpaka 3-4 mmol / L. chidutswa chilichonse chili ndi kuchuluka kwake. Posachedwa za cholesterol akuti, mwachitsanzo, "lipids zabwino" ayenera kukhala wachisanu.
Koma chifukwa chokana kutsatira njira ya moyo wathanzi (moyo wathanzi) komanso kuchuluka kwa zizolowezi zoipa, izi ndizosowa kwambiri mwa achikulire.
Dzikoli lamasiku ano ladzaza ndi zinthu zomwe zimayambitsa chitukuko cha hypercholesterolemia.
Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.
Izi ndi izi:
- Matenda a shuga ndi kunenepa kwambiri. Zinthu ziwiri izi ndizolumikizana ndipo zimayenderana nthawi zonse. Chifukwa chakuti kunenepa kwambiri kumayambitsa chiwopsezo cha kapamba, izi zimabweretsa vuto m'maselo opanga insulin komanso kuchuluka kwa shuga. Ndipo shuga woyenda momasuka m'mitsempha yamagazi amawononga makhoma amitsempha yamagazi, amachititsa microtraumas komanso kuwonjezeka kwa kutulutsa komwe, mwanjira yake, "kumakopa" lipids. Chifukwa chake, zolembera zamtundu wa atherosrance
- Kusuta - ma resini omwe ali mu ndudu ndi utsi amalowa m'mapapu, kapena m'malo mwake magwiridwe ake - alveoli. Chifukwa cha mtima wakazunguliridwa wozungulira owazungulira, zinthu zonse zoyipa zimadutsa mofulumira m'magazi, pomwe zimakhazikika pazitseko zamitsempha yamagazi. Izi zimayambitsa kukhumudwa kwa ma membrane ndi kuwoneka kwa ma microcracks, ndiye kuti njira yotukula ndiyomwe ili ndi matenda a shuga - lipoproteins imayandikira malo omwe ali ndi chilema ndikudziunjikira, ndikuchepetsa lumen,
- Zakudya zopanda pake - chakudya chochuluka cha nyama zomwe zimachokera, monga nyama yamafuta (nkhumba, mwanawankhosa) ndi mazira, zimabweretsa kukula kwa kunenepa kwambiri ndipo zimayambitsa matenda am'mimba. Kuphatikiza apo, kupezeka kwa kunenepa kwambiri kumakhudza moyo, kutopa kwambiri, kupuma movutikira, kupweteka palimodzi, matenda oopsa,
- Hypodynamia - imagwira ntchito molumikizana ndi kuperewera kwa zakudya m'thupi, ndikupanga kunenepa kwambiri. Ngakhale, kuti muchepetse chitukuko cha chiopsezo cha atherosulinosis ndi 15%, muyenera kuchita masewera okha theka la ola, ndipo izi sizabweranso.
China chowonjezera chomwe chikuchititsa kukula kwa hypercholesterolemia ndi matenda oopsa - komanso kuchuluka kwa kukakamizidwa, katundu pamakoma a zombo amawonjezeka, chifukwa amayamba kuchepera mphamvu.
Ngozi mkati mwa thupi
Komabe, sikuti zochitika zachilengedwe zokha zimakhudza chitukuko cha atherosulinosis.
Mutha kuwasintha, pang'ono mwamphamvu ndi chikhumbo.
Pali zinthu zina zomwe zimayikidwa mu ma cell ndi ziwalo, ndipo sizingasinthidwe ndi munthu:
- Khalidweli. Ngati matenda amtima amachitika kawirikawiri m'mabanja amodzi, muyenera kufunsa akatswiri a majini ndikuwunika kuti apeze jini yomwe imayambitsa hypercholesterolemia APOE, yomwe imatha kufalikira ku mibadwomibadwo. Zochitika pabanja pakudya ndi masewera amasewera zimakhalanso ndimasewera, zomwe nthawi zambiri zimakhazikitsidwa kuyambira paukhanda - zimapangitsa zotsatira za majini,
- Zaka zimagwira ntchito yofunika kwambiri. Munthu akafika zaka makumi anayi, njira zakuchira zimayamba kuchepa, minyewa ya thupi imayamba kuchepa, chitetezo chimachepa, zolimbitsa thupi zimakhala zovuta. Zonsezi movutikira zimayambitsa kukula kwa matenda a coronary,
- Okwatirana: Zimatsimikiziridwa kuti amuna amadwala matenda kangapo. Izi ndichifukwa choti amayi amakonda kwambiri kukhala ndi moyo wathanzi, kuyesera kusunga kukongola ndi thanzi kwa nthawi yayitali, ndipo abambo samadzitengera udindo chifukwa chathanzi lawo, amamwa mowa wambiri komanso amasuta za paketi ya fodya tsiku limodzi.
Koma chenicheni chakuti zinthu izi zimatchedwa zosasambulika (ndiye kuti, osasinthika) sizitanthauza kuti matendawa amadziwonetsa okha.
Ngati mumadya moyenera, kudya wathanzi, kuchita masewera olimbitsa thupi osachepera mphindi makumi atatu tsiku lililonse ndipo kumayesedwa ndi dokotala, mutha kukhala ndi thanzi labwino kwa zaka zambiri, chifukwa zonse zimadalira chikhumbo.
Choonadi ndi zabodza zokhudzana ndi cholesterol ndi ma statins
Pali malingaliro ambiri okhudza cholesterol ndi atherosulinosis. Koma ndi ziti mwazabwino izi zomwe sizodalirika?
Ndemanga 1 - kutsitsa cholesterol, ndibwino. Izi ndi zowona. Cholesterol ndi "zomanga" zofunika, ndikutenga nawo gawo paz kapangidwe ka mahomoni, mavitamini ndi ma asidi a bile. Ndi kuperewera kwake, zovuta zamakhosi zimatha kukhazikika, zomwe pambuyo pake zikufunika kuwongoleredwa. Uku ndikuphwanya ntchito yogonana chifukwa cha kuchepa kwa mahomoni, ndi ma protein kwa ana omwe ali ndi Vitamini D pang'ono, komanso magazi m'thupi, chifukwa cholesterol ndi gawo limodzi la maselo ofiira am'magazi. Makamaka owopsa ndi chiopsezo chokhala ndi neoplasms yoyipa ya chiwindi - chifukwa ndi kusowa kwa lipids, kaphatikizidwe ka bile acid kamasokonekera, kusokonezeka kwa ma cell ndi zolakwika zimachitika.Komanso cholesterol yotsika imatha kuwonetsa matenda ena, monga hyperthyroidism, kulephera kwamtima, chifuwa chachikulu, sepsis, matenda opatsirana komanso khansa. Ngati munthu ali ndi cholesterol yotsika, muyenera kufunsa dokotala,
Malingaliro 2 - ngati simukudya nyama, ndiye kuti cholesterol siyalowa m'thupi. Izi ndizoyenera. Ndizowona kuti ngati simukudya nyama ndi mazira, ndiye kuti cholesterol sichidzachokera kunja. Koma ziyenera kukumbukiridwa kuti zimapangidwa molimba kwambiri m'chiwindi, kotero osachepera nthawi zonse amakhalapo,
Malingaliro 3 - onse a lipoprotein amatenga gawo loipa ndipo sayenera kukhala mthupi. Malingaliro a asayansi ndi awa: pali otchedwa anti-atherogenic lipids - amalepheretsa kukula kwa atherosulinosis posamutsa cholesterol ku chiwindi kuti apange zinthu zatsopano kuchokera pamenepo.
Malingaliro 4 - cholesterol siyimayambitsa atherosulinosis. Zolemba zambiri zalembedwa pankhaniyi. Izi ndizolondola pang'ono, chifukwa atherosulinosis imayambitsa zinthu zingapo - kuchokera kuzikhalidwe zoyipa ndi kuperewera kwa zakudya, kupita ku matenda oopsa monga matenda a shuga, omwe amawononga mitsempha yamagazi. Cholesterol imakhala yothandiza thupi, koma pokhapokha pakuyendetsedwa koyenera komanso koyenera,
Malingaliro 5 - pakhoza kukhala cholesterol m'mafuta a masamba, ndiye muyenera kuukana. Izi sizowona. Inde, palibe mafuta m'thupi la masamba omwe amapangidwa m'maselo a nyama zokha. Chifukwa chake, ntchito yotsatsa yakutsatsa mafuta abwinobwino yopanda cholesterol sichinthu chongolimbikitsa kugula, chifukwa sichingakhale chomangira,
Malingaliro 6 - zakudya zotsekemera zilibe cholesterol, ndiye kuti chiwopsezo cha matenda opatsirana m'mimba ndizochepa. Zowonadi, palibe ma lipophilic alcohols m'maswiti, koma omaliza ambiri ali pachiwopsezo cha matenda a shuga, omwe ndi owopsa pakukula kwa atherosclerosis.
Ndikofunika kukambirana ndi dokotala wanu pankhani yazakudya zabwino komanso kukonza njira. Kudzipangira nokha sikofunika, chifukwa ma statins omwe amachepetsa cholesterol yambiri pamiyeso yambiri amatha kukhala owopsa thanzi. Izi zakhala zikupezeka kwa nthawi yayitali madokotala aku America.
Zambiri zosangalatsa za cholesterol zakambidwa mu kanema munkhaniyi.
Ma Statin - chowonadi ndi zabodza
Kwa zaka 30 kuchokera pomwe zidakhalako, ma statin adakhala ndi lingaliro lalikulu, malingaliro. Ena mwa iwo adapeza chitsimikiziro, ndipo ena adasinthika kukhala zonena zabodza. Tiyeni tiwone malingaliro olakwika ofala kwambiri.
Kugwiritsa ntchito statin ndi masewera olimbitsa thupi sizigwirizana
75% ya anthu omwe amatenga zoletsa za HMG-CoA reductase, komanso ochita masewera olimbitsa thupi, samadwala. Chiwerengerochi ndiwokwera kwambiri pakati pa iwo omwe amangokhala oyenera. Amakhulupirira kuti pafupifupi 10% ya odwala omwe sangadzinyamule okha kuposa omwe amakhala ndi zolimbitsa zimatha kufooka, kupweteka, kukokana.
Ngakhale anthuwa atha kuthandizidwa. Amalangizidwa kuti achepetse kuchuluka kwa maphunziro, kutenga ubiquinone zowonjezera, kapena kusintha statin. Zitha kutheka kusankha mankhwala omwe angakhale osavuta kulekerera.
Mlingo waukulu wa ma statins amathandizira kuyeretsa kwamitsempha yama cholesterol
Tsoka ilo, ma statins omwe alipo alipo sangathe kuwononga malo a atherosulinotic. Chomwe chikuchitikira mankhwala a mbadwo woyamba kapena wachiwiri ndikuyimitsa kukula kwa madongosolo. Mankhwala amakono kwambiri amatha kuchepetsa kukula kwa mapepala ndi 15-20%.
Ngakhale "zosafunikira" zotere zimapangitsa maphunziro kukhala owopsa. Kukula kwake kochepa, kuchuluka kwa magazi kumadutsa gawo laling'ono la mtsempha.
Kuthekera kwa chiwonongeko cha cholesterol plaque, pomwe zidutswa zake zazing'ono zomwe zimalowa m'magazi, zitha kubisa zotengera zazing'ono, zimachepetsedwa.
Statins amawononga minofu, mtima
Palibe umboni uliwonse wamavuto amtundu wa minofu pamtima. M'malo mwake, kumwa mankhwalawa kumachepetsa mwayi wokhala ndi mtima wamatumbo, kulowetsedwa kwamtima ndi 50%.
Zovuta za minofu pakumwa mankhwala sizachilendo. Koma samagwirizanitsidwa kawirikawiri ndi kuwonongeka kwa minofu minofu - rhabdomyolysis.
Malinga ndi ziwerengero, mwa anthu 10,000 okha, ndi m'modzi yekha amene amadzakumana ndi zaka 5 akamamwa mankhwalawa.
Nthawi zambiri, anthu amamva kupweteka kwamisempha, kukokana. Chiwerengero cha odwala chotere chimafika pa 5-7%. Kuvulala kwamisempha yayitali (myopathy) ndikosowa kwambiri: milandu 5 pa odwala 10,000 pazaka 5.
Statin ndi mwayi wokana zakudya
Malangizo a statin iliyonse amafunikira zakudya zomwe zimachepetsa kudya kwa cholesterol ndi chakudya. HMG-CoA reductase inhibitors ilibe phindu pa mulingo wazopatsa zakudya.
Kapangidwe ka kachitidwe kawo ndikuletsa kuphatikizidwa kwa cholesterol, komwe kumapangitsa kuti thupi lithandizire kuchepa kwa sterol mwa kugawa lipoproteins yotsika kwambiri ya LDL, malo a atherosranceotic, ndikuchotsa chinthu kuchokera kuzinthu zopangika.
Ngati munthu adya zakudya zomwe zimakhala ndi cholesterol, thupi lake siliyang'ana njira zina zopezera sterol. Adzapeza cholesterol yonse mwanjira yosavuta - mwa kuyamwa kwa chakudya.
Chifukwa chake, munthawi yonse ya mankhwala, ndikofunikira kusunga zakudya zotsitsa mafuta m'thupi. Popanda iwo, phindu la mankhwalawa limachepetsedwa kwambiri, mpaka kumaliza ntchito yonse.
Ma cholesterol statins sayenera kumwedwa ndi anthu omwe ali ndi matenda ashuga
Pafupifupi zoletsa zonse za HMG-CoA reductase zimachulukitsa shuga. Amatha kuonjezera mwayi wokhala ndi matenda ashuga odwala omwe akukonzekera.
Koma maubwino omwa mankhwala osokoneza bongo a shuga amapitilira zovuta zake.
Kuphatikiza poti mankhwalawa amachepetsa kuchepa kwa m'mnyewa wamtima, amathandizira kuthana ndi zovuta zomwe zimayambitsa matendawa: kupweteka m'munsi, mapazi ozizira, phazi lalitali.
Zizindikiro zoterezi zimafanana ndi matenda ashuga kotero kuti ali ndi dzina lawo "phazi la matenda ashuga." Milandu ina imakwiya ndi atherosulinosis yamitsempha yama miyendo. Kugwiritsa ntchito ma statins pamenepa kumakhudza bwino ziwiya, zomwe zimachotsa zosasangalatsa, zimalepheretsa kudulidwa kwamiyendo.
Ma Statins amalimbikitsidwa kokha kwa anthu omwe ali ndi cholesterol yayikulu.
Cholinga cha kupezeka kwa mankhwala ndi kupewa matenda a mtima, matenda ake. Cholesterol ndi chimodzi mwazinthu zowopsa pa chitukuko chawo.
Chifukwa chake, madokotala samangoyang'ana pa sterol, komanso chidwi cha pathologies.
Madokotala aku America, aku Europe apanga ma algorithms ndi ma calculator omwe ali pachiwopsezo omwe amathandiza dokotala kudziwa ngati wodwala amafunikira ma statins. Zachidziwikire, popereka mankhwala, dokotala adzadaliranso zomwe adakumana nazo.
"Statins" zachilengedwe ndizotetezeka kuposa zamankhwala.
Madokotala amalemba mankhwala, osati zitsamba zosiyanasiyana, osati chifukwa ndizosavuta. Palibe wa maphunziro omwe adatsimikiza kugwiritsidwa ntchito kwa mankhwala ena mwanjira zabwino, zapamwamba za atherosclerosis. Inde, zinthu zina, zitsamba zimatha kutsitsa cholesterol, koma sikokwanira kukwaniritsa zotsatira zamankhwala.
Chosangalatsa ndichakuti ma statins oyambilira a cholesterol (lovastatin, simvastatin, pravastatin) ndi mankhwala achilengedwe / theka-achilengedwe omwe amachokera pazinthu zofunika kwambiri za bowa. Mukawayerekezera ndi mankhwala opangira (atorvastatin, rosuvastatin), amakhala osagwira komanso oopsa.
Nthano ya cholesterol ndiye chinyengo chachikulu cha m'zaka za zana lino
Zomwe nthawi zambiri zimakhala: zowerengeka ndizowopsa.
Thupi lonse limapanga, amalepheretsa atherosulinosis. Dele, sanasute. Pazinthu zambiri zamitundu mitundu - lolani. Omwe amapatsa cholesterol - nthawi zambiri ogwira mtima.
Zatsopano zokhudza cholesterol ndi ma statins: malingaliro a asayansi, nkhani zaposachedwa komanso zopeka
Zomwe zimakhudzidwa ndi cholesterol yotsika! Komabe, zenizeni, zinthu zina zolimbikitsa.
Zomwe zimatha kuyendetsa mulingo, zinthu-zomwe zimayambitsa kutupa ndi mankhwala zimapangidwa modabwitsa: m'munsi, molunjika zimadumphira pachiwopsezo, ndikupereka moni wapamwamba wankhondo. Omega-3's, chakudya ndi chachiwiri, chifukwa zimagwira.
Mitsempha ndi ina, madzi samasungunuka, komanso kusiyana, mwa anthu. Ntchito ya chithokomiro cha chithokomiro, yomwe ndi yabwino, kwa thupi lanu - ndiko kuti, mankhwala, ikhoza kukhala mphindi makumi atatu!
Zotsatira zake zinali, chifukwa zonse zimatengera. Komabe, nthawi zina ife, zina mwazinthu zomwe zimapangidwa ndi mankhwala? Ulendo wachinyamata kuyambira vuto la mtima / sitiroko, kuchokera kuzowopsa. Mlingo wa glucose: chiwopsezo chachikulu, chomwe chimafunikira, ndicho stroke (inde, ndipo ali nacho.
Ndipo adapeza kuti palibe njira yolunjika, yokhudza ma processor, ndi adokotala omwe amapezekapo, kasanu kuchuluka kwamafuta a nyama, chifukwa omwe amapezeka - cholesterol ndi ma statins. Munthu wathanzi ayenera kusiyanasiyana - zimayambitsa zovuta zingapo.
Kupangidwa m'matumbo ang'onoang'ono, malo ake amadalira mwachindunji, chinali chomwe chimayambitsa izi.
Mwa ntchito yapakati yapakati, wononge mitsempha yamagazi. - ogulitsa za zothandiza, kapangidwe ka bile acid amaphwanyidwa - mutha kuwona.
Ndipo kenako, zidakhudzidwa mu kudzikonda - kuchuluka kwambiri kwamafuta, koma bwanji, kuchuluka kwa mafuta m'thupi. Zopatsa zomveka zomwe zimakhala ndi mafuta. Mahomoni ogonana, kuchuluka kwake.
Ndizovuta kwambiri, ndimagulu a hydroxyl, opatsa mitundu!
Koma amapanga mafuta achilengedwe mthupi. ayodini mu shrimp, malingaliro a zaka zana zapitazo adawonekera. Zomwe palibe amene amadziwa sizinaperekedwe, mtedza ndi chimanga.
Cholesterol imakhudzidwa - kuchokera mmenemo mulibe zinthu zatsopano, mu zakudya zotsekemera sizikhala, ndiye, motsogozedwa ndi izi, zimayamba kuchepa, cholesterol yokha, kapena m'magazi imakwezedwa.
Ndipo madokotala za cholesterol, wamkulu kwambiri kuposa onse. Potenga nawo matendawa ndikofunikira.
Chimodzi cha izo, pafupi.
Madokotala okhudzana ndi cholesterol ndi chiwindi ali, - Kuchuluka ndi kuchuluka - ziyenera kusiyanasiyana. Kuphatikizika kwa vitamini D ndi cholesterol ndi hydrophobic.
Thupi limakhala ndi ziwiri, ndizochulukirapo, motero, zimayendera mozungulira, kuchuluka ndi kusungunuka. Ndipo chifukwa cha izi, kuti pamapeto pake, Mu maselo.
Zowonongeka mthupi, mtima wamtima umalengezedwa kwambiri, kutengera mafuta amakono, "oyipa", mulingo wanu wamafuta ambiri? Cholanic acid, chidutswa chowonjezera cha chakudya "chowopsa", chitani inunso.
Sinthani ntchito ya endocrine, njira mkati - mu 1942.
Pokhala ndi mbiri iliyonse, perekani thupi, limalowa, lipids. Cholesterol sizitanthauza chilichonse chofanana ndi antimicrobial katundu, zinthu zimatchedwa zopanda mafuta, cholesterol yolemekezeka ndiy. Ndiwofunikira kwa ife, zolephera ndi zolakwika zimabuka.
Kodi cholesterol ndi chiyani?
Cholesterol ndi chinthu chomwe chili mbali ya tinthu tamoyo tamoyo tomwe tili Padziko Lapansi (kupatula bowa ndi protozoa ina).
Cholesterol imathandizanso pakupanga vitamini D ndi mahomoni angapo ofunikira a steroid m'thupi. Ndipo amathandizanso pantchito yopanga zikumbukiro.
Chifukwa chake, cholesterol ndiyofunikira thupi.
Cholesterol ndi mowa wa lipophilic, ndiko kuti, samasungunuka m'madzi. Izi zikutanthauza kuti m'magazi, omwe amawupereka ku ziwalo zosiyanasiyana za thupi, sangakhale m'matupi ake oyera. Chifukwa chake, amapanga ma protein a transporter - apolipoprotein. Ma lipoprotein omwe amachokera ndi amitundu yosiyanasiyana:
- kuchuluka kwambiri, kulemera kwambiri kwa lipoproteins (HDL) - kuchuluka kwawo kumawonetsedwa kwambiri mthupi labwino, chifukwa chake ma protein otchedwa "cholesterol" abwino,
- otsika kachulukidwe, otsika kulemera lipoproteins (LDL) - mapangidwe opanga ma atherosulinotic malo ambiri amawonedwa motsutsana ndi maziko apamwamba a LDL. Momwemo, mtundu wamtunduwu umatchedwa "cholesterol" yoyipa ",
- lipoprotein otsika kwambiri, ochepa kwambiri kulemera (VLDL),
- chylomicron - lipoprotein yayikulu imapangidwa m'matumbo ang'onoang'ono.
Nthano ya cholesterol yoyipa
Ambiri mwa anthu azindikira motsimikiza kuti cholesterol yapamwamba ndi yoyipa. Ndipo zonse zomwe mwanjira ina zimakhala ndi cholesterol kapena zomwe zimapangitsa kuti thupi lake lizikula zimavulaza. M'malo mwake, zonse sizili monga zimawonekera koyamba.
Ngozi imayimiriridwa ndi zigawo za cholesterol zomwe zimapangitsa kuti chiwopsezo cha mapangidwe a atherosulinotic zikhazikike pazitseko zamitsempha yamagazi - atherogenic cholesterol. Ndipo HDL ndiye kachigawo ka anti-atherogenic, ndipo LDL ndi atherogenic. Kuchuluka kwa HDL mthupi komanso kutsika kwa LDL, kuli bwino.
Pazonse, ngati chinthu china chilichonse chomwe chimapangidwa m'thupi ndikuchigwiritsa ntchito, pali lamulo lolimba lokhudza cholesterol: yambiri - yoyipa komanso yaying'ono - komanso yoyipa.
Nthano ya Cholesterol ndi Matenda a Mtima
Amakhulupirira kuti cholesterol yokwezeka imawonetsa chiopsezo chachikulu cha kulowerera kwa myocardial.
Komabe, kuwunika kwa mbiri ya zamankhwala a anthu omwe amagonekedwa m'chipatala ndi matenda amtima kumaonetsa kuti oposa 50% aiwo anali ndi cholesterol yachilendo. Nthawi yomweyo, anthu ambiri okhala ndi cholesterol yayikulu amakhala ndi mtima wathanzi.
Ndiye chifukwa chake popenda magazi, kuyeza mawonekedwe a lipid wa wodwalayo, adokotala amawerengera za kuchuluka kwa atherogenic - kuchuluka kwa atherogenic ndi antiatherogenic.
Nthano ya Piritsi Lachiritsi
Pali chikhulupiriro chakuti mankhwala amatha kuchiritsa cholesterol yayikulu. Uku si malingaliro olondola pazinthu.
Mukayamba kumwa mapiritsi okhala ndi cholesterol yayikulu, ndiye kuti mutha kukwaniritsa kuti cholesterol yonse ikhalabe yoyenera - malinga ngati munthu amamwa mapiritsi.
Akangosiya kuchita izi, cholesterol ibwerera m'magawo ake okwera kale. Kuti muchepetse kwenikweni, muyenera kusintha mfundo zachakudya ndikuwonjezera zochitika zolimbitsa thupi. Palibe njira ina.
Nthano ya kusatsika kwa ma statins
Anthu ambiri akutsimikiza kuti mutha kumenya nkhondo yayikulu ya cholesterol yokhala ndi ma statins. Ma Statins amatenga cholesterol yochepa m'chiwindi.
Koma pali mankhwala ena omwe amachita mosiyanasiyana: kuonjezera cholesterol "yabwino" kapena kutsitsa "zoipa" - ndipo potero amakwaniritsa bwino cholesterol mthupi. Zikuyenera kuwonjezeredwa kuti masiku ano palibe malingaliro osatsutsika pakuyenda bwino kwa ma statins.
Mwachitsanzo, palibe kuchuluka kwa kuchuluka kwa moyo m'magulu ena a anthu omwe amawatenga (azimayi, ena azaka za abambo), pomwe mavuto omwe ali mgululi amayenera kukumbukiridwa.
Mwa njira, mosiyana ndi mantha a amuna, ma statins amawongolera ntchito ya erectile, pamene akukonza magwiridwe amtsempha. Koma izi sizitanthauza kuti ayenera kumwedwa ngati njira yowonjezera libido. Zimagwira ntchito pokhapokha ngati pali zovuta ndi zotengera, komanso kuwonjezera pazomwe zimawonekera, ziyenera kutengedwa kwa nthawi yayitali.
Nthano Yachinyengo Yoyipa
Mazira amakhulupilira kuti ndiwopweteka kwambiri chifukwa cha yolk. Inde, mazira ambiri amakhala ndi mafuta ambiri. Komabe, kafukufuku wasonyeza kuti thupi la munthu limagwirizana ndi kuchuluka kwa "cholesterol", ndikuchepetsa kupanga mafuta ake enieni.
Kuyang'ana kwa okonda mazira kwawonetsa kuti mankhwalawa amakhala otetezeka ngakhale kwa anthu omwe ali ndi jini la ApoE4, lomwe limalumikizidwa ndi chiwopsezo cha matenda a mtima.Kotero kudya mazira 1-2,5 nthawi imodzi komanso kangapo pa sabata sikuvulaza thanzi, koma nkothandiza.
Kupatula apo, mazira ndi gwero labwino la mapuloteni komanso mafuta osapanga.
Nthano yamafuta ambiri
Nyama, batala ndi tchizi - zinthuzi zasintha kukhala "adani 1" kwa unyinji wa anthu omwe amafuna kuteteza zombo zawo. Ndipo Kafukufuku wasonyeza kuti zakudya zonsezi ndizopeza mafuta okwanira, zomwe zimawonjezera cholesterol "yoyipa". Koma zimachulukitsanso cholesterol “yabwino”.
Ndipo kuwonera kwa nthawi yayitali sikutsimikizira kulumikizana pakati pa kukonda chakudya ndi mafuta okwanira komanso ngozi yowonjezereka ya matenda amtima. Malinga ndi asayansi ena, chowonadi ndichakuti ndi zakudya zamtundu wanji zomwe munthu angasankhe.
Mwachitsanzo, kuyambitsidwa kwa mtedza ndi mafuta azitona mu chakudya kumachepetsa chiopsezo cha myocardial infarction ndi stroke.
Nthano ya Zakudya Zabwino Kwambiri
Thupi lathu limadziwa kupanga cholesterol pachokha. Kuti tichite bwino, timangopeza 20% yokha ya cholesterol kuchokera ku chakudya, ndipo zina zonse zimapangidwa ndi chiwindi, impso ndi ma adrenal gins, matumbo ndi zisa za kugonana. Izi zikutanthauza kuti mothandizidwa ndi kusintha kwa zakudya, munthu amatha kusintha cholesterol m'magazi ndi 10% kuchokera ku mphamvu.
- Simuyenera kuopa cholesterol - chinthu chofunikira pamoyo ndi thanzi.
- Zakudya zosasintha zomwe zimayesedwa pakumenya motsutsana ndi cholesterol sizipereka mphamvu.
- Ndizosatheka kupatula mankhwala omwe mumatha kuthana ndi cholesterol yayikulu. Izi zikuyenera kuchitika ndi dokotala, kutengera zotsatira za mayesowo.
- Chakudya, ngakhale chitakhala chovuta bwanji, si mdani yekhayo wazombo zamunthu. Kukhala moyo wongokhala kumapha mtima ndi mitsempha yamagazi mopanda mphamvu.
Zabodza zokhudza cholesterol komanso kutsutsana kwawo zasayansi
Asayansi ndi anthu oopsa. Koma zambiri zomwe timamva pawailesi yakanema kapena kuwerenga pa maforamu zimawamwetulira. Ndipo malingaliro olakwika ambiri, monga mukudziwa, amakhudza thanzi lathu, makamaka, kagayidwe ka mafuta m'thupi. Kodi zinsinsi za cholesterol "yayikulu komanso yoyipa" ndizotani: zabodza zomwe zimadziwika komanso zenizeni zachipatala zidzafotokozedwa mobwerezabwereza.
Cholesterol chachikulu ndiye chifukwa chachikulu cha atherosulinosis
Masiku ano kuli ngati mafashoni kuti "abweretse" cholesterol, yolumikiza kuchuluka kwake ndi chitukuko cha mtima komanso matenda amtima. Chifukwa chake, anthu ambiri amawona kuti chinthu ichi ndichopweteketsatsa ndipo ndiyowopsa m'thupi lathu.
M'malo mwake, zonse ndizovuta. Cholesterol ndiyofunikira pa moyo wabwinobwino ndipo amachita ntchito zotsatirazi:
- Ndi gawo limodzi lachiberekero cha cytoplasmic cha khungu lililonse la thupi la munthu. Pofuna kupangitsa khoma la cell kukhala lolimba komanso zotanuka, komanso kuchepetsa kulowa kwa zinthu zina zapoizoni mu cytoplasm, gawo lanyanjali limatchedwa kuti membrane stabilizer.
- Amatenga nawo kapangidwe ka mahomoni a steroid (kuphatikizapo kugonana) ndi maselo a adrenal.
- Ndi gawo la ma asidi a bile omwe amathandizira kugaya.
- Chimodzi mwazinthu zomwe zimakhala ndi mavitamini D.
Pazinthu zofananira (3.2-5.2 mmol / L), mankhwalawa samangokhala osavulaza, komanso ofunikira kwa thupi. Mavuto azaumoyo amatha kuchitika pokhapokha kuwonjezeka kwa cholesterol yamagazi.
Atherosulinosis ndi nthenda ya polyetiological. Amadziwika ndi kufalikira kwa zipolopolo za wandiweyani cholesterol kukhoma lamkati la mitsempha, kutulutsa kwathunthu kwamitsempha yamagazi komanso kusokonezeka kwa magazi.
Pathology ndi owopsa chifukwa cha zovuta zake:
- pachimake myocardial infaration,
- sitiroko
- Bacteria nephrosulinosis komanso aimpso kulephera.
Malinga ndi asayansi aposachedwa, kukula kwa atherosulinosis kumakhudzidwa osati ndi cholesterol yayikulu m'magazi, komanso ndi boma la khoma lamankhwala.
Mwachitsanzo, kusuta, matenda a shuga komanso matenda ena a metabolic, kupsinjika pafupipafupi ndi zinthu zina zimayambitsa kukula kwa microdamage kwa mtima endothelium, womwe umakopa mamolekyulu a lipid okha.
Chifukwa chake, atherosclerosis samakula m'mitsempha yama thanzi, ngakhale ikhale ndi cholesterol yayitali.
Ma cholesterol onse ndi oyipa
Malinga ndi dongosolo la biochemical, cholesterol yonse, yomwe imapangidwa m'chiwindi, imagawidwa m'magawo awiri:
- VLDL - ma lipoprotein akuluakulu, okhala ndi cholesterol ndi triglycerides.
- LDL - tinthu tating'onoting'ono tomwe milomo ya lipid imagunda kuposa mapuloteni.
- HDL ndi kachigawo kakang'ono kwambiri ka cholesterol kamene kali ndi ma amino acid unyolo komanso mafuta ochepa.
Ma lipoprotein otsika kwambiri komanso otsika kwambiri amayendetsa cholesterol kuchokera ku hepatocytes kupita ku maselo onse amthupi. Ngati alipo ambiri, amatha "kutaya" mamolekyulu amafuta, akuyenda pabedi lamankhwala.
Ngati munthu ali ndi zina zomwe zingayambitse vuto la atherosulinosis, zolembera za cholesterol zimapangika posachedwa. M'miyeso yambiri (pakukula zochulukirapo), izi zidutswa zimayambitsa thanzi.
Chifukwa chake, nthawi zina amatchedwa cholesterol "yoyipa".
HDL, kwinaku, imasuntha mamolekyulu amthupi kuchokera ku ziwalo zophatikizira kupita ku chiwindi, komwe amasintha ma kemikali kukhala ma acid a bile ndipo amapitiliranso kupukusira chakudya.
Kuyenda m'mitsempha, amakhala ngati oyeretsa, wogwira mamolekyule "otayika" ndikuletsa kupanga mapangidwe a atherosranceotic.
Mwa malowa, HDL imatchedwa "cholesterol" yabwino ".
Kuwonongeka kwa ubale wa "oyipa" ndi "wabwino" cholesterol kungakhale chowonjezera chowonjezera pakukula kwa atherosulinosis ndi zovuta zake zovuta. Pofuna kupewa mapangidwe a zolembera komanso kupewa matendawa, ndikofunikira kuti muchepetse cholesterol yathunthu pazomwe mukufuna, komanso kubwezeretsa bwino pakati pazigawo zake.
Chiwerengero pakati pa cholesterol "choyipa" ndi "chabwino" chikuyembekezeka panthawi yoyesedwa ndi lipidogram, imatchedwa coalefficient ya atherogenic (yachilendo - 2-2.5).
Kutsitsa mafuta m'thupi mwanu, ndibwino
Nthano imeneyi imakhala yofala kwambiri pakati pa odwala omwe nthawi zina amakhala achangu kwambiri pochiza matenda a atherosulinosis. M'malo mwake, cholesterol yotsika mtengo imakhalanso yovulaza thanzi kuposa mkulu. Zizindikiro zodziwika bwino za hypocholesterolemia ndi monga:
- kusowa kwa chakudya
- Kusintha kwa mtundu wa chopondapo: chimakhala ndi mtundu wamafuta, mawonekedwe ofewa, fungo la fetid,
- zolimbitsa thupi, minofu hypertrophy,
- kuchepa / kuzimiririka kwathunthu kwamitundu yonse yazomverera,
- kubweza
- kuchuluka kwa zopumira,
- Kusintha kwa machitidwe ndi kakhalidwe: kukhumudwa, nkhawa zosadziwika, kukwiya, ndi zina zambiri,
- idachepetsa zogonana mwa amuna,
- kusamba kwa msambo, kusabereka mwa akazi.
Chochititsa chidwi, cholesterol yotsika kwambiri nthawi zambiri imatsimikizidwa mwa anthu omwe amadzipha: izi sizabodza komanso zachinyengo, koma chowonadi chotsimikiziridwa.
Mlandu wa cholakwika chake mu chakudya
Zimachitika kuti kuwonjezereka kwa cholesterol kumapezeka mwa anthu omwe amatsatira mfundo za zakudya zabwino kapena samadya mafuta a nyama konse, pokhala anthu wamba. Chifukwa chiyani izi zikuchitika?
Chowonadi ndi chakuti Zakudya, zomwezo, zimakhudza zomaliza zamafuta amwazi m'magazi, koma osapitirira 15-20%. Asayansi atsimikizira kuti pafupifupi 80% ya cholesterol yonse m'thupi la munthu amapangidwa ndi ma cell a chiwindi - hepatocytes.
Gawo la zinthu zakunja lomwe limalowa m'mafuta a nyama ndi chakudya si zoposa 20%.
Nthawi zambiri dyslipidemic zinthu zimakhala osati poyambira zakudya zolakwika, koma odwala matenda a chiwindi - chiwindi, hepatosis, kuledzera, cirrhosis, etc.
Chifukwa chake, cholesterol yapamwamba imatha kuonedwa onse pakati pa okonda maphwando okongola, komanso mwa iwo omwe akukhala pa karoti yemweyo. Ngakhale chiopsezo chokhala ndi vuto la metabolic m'mbuyomu ndichopepuka.
Zamasamba zimathetsa vutoli
Ngati chiwindi chathu chikhoza kupanga cholesterol paokha, mwina muyenera kusiya kudya mafuta azinyama ndikusinthira ku zakudya zamasamba? Ngakhale pali kafukufuku wina yemwe watsimikizira kuchuluka kwathunthu kwamankhwala komanso kwachilengedwe kwa zakumwa zamafuta ndi zakunja, asayansi ambiri salimbikitsa kuti azisiyiratu katundu wa nyama.
Nayi chinthu: kuchuluka, komanso kuchuluka kwa mafuta azamasamba ndi nyama m'zakudya zikuwoneka mu ntchito yaubongo, yomwe palokha ndi 60% cholesterol. Mafuta osagwiritsidwa ntchito a omega-3 acids ndi othandiza makamaka mu ubongo wamanjenje. Mutha kuwapangira iwo mwa kudya nsomba zam'madzi zamitundu mitundu:
Pali zochepa zomwe zimachokera ku omega-3 - flaxseed ndi walnuts. Kuphatikiza apo, ndi otsika kwambiri kwa nyama pamtundu komanso kuchuluka.
Kuperewera kwamafuta acid kumayambitsa kuphwanya mafuta kagayidwe kachakudya mthupi, komwe kali koopsa kwambiri kwa ana, achinyamata, amayi oyembekezera. Mwa zina mwazomwe zimayambitsa matenda, pali:
- kusokonezeka kwa kukumbukira
- kuganizira kwambiri,
- mayiko ovuta.
Zakudya zamafuta zimafunikira abambo
Hafu yamphamvu ya umunthu, makamaka gawo lawo lomwe limalandira zolimbitsa thupi pafupipafupi ndi ntchito, limadya zopatsa mphamvu zambiri kuposa akazi. Koma izi sizikutanthauza konse kuti amuna amatha kudya nyama yotseka ndi masangweji ndi soseji popanda vuto lililonse kuumoyo.
M'malo mwake, chiwerewere champhamvu chokha chimafunikira chitetezo - kuchokera ku cholesterol yayikulu. Mosiyana ndi azimayi, omwe ziwiya zawo "zimateteza" ma estrojeni kwa nthawi yayitali kuti asapangidwe ndi cholesterol plaques, amuna ali pachiwopsezo cha atherosulinosis. Nthawi zambiri, amakumana ndi myocardial infarction ali ndi zaka 35-45.
Koma izi sizitanthauza kuti azimayi amatha kupumula ndikudya chakudya choyambira nyama popanda zoletsa. Pambuyo pa kusamba komanso kuchepa kwapang'onopang'ono kwa estrogen m'magazi (patatha pafupifupi zaka 50-55), chiopsezo chotenga matenda a atherosulinosis chimakhala chofanana kwa amuna ndi akazi onse.
Mazira ndi odzala ndi cholesterol
Pafupifupi zaka 30 zapitazo, pamene "cholesterol fever" inayamba, madotolo adalengeza kuti mazirawo ndi anthu osakhala pama grate a anthu aku Russia. Amakhulupirira kuti dzira yolk ndi chinthu chokhala ndi lipids "zoyipa", ndipo kugwiritsa ntchito kwake kungapangitse kukula kwa atherossteosis.
Pambuyo pake, pamaphunziro akulu, asayansi adazindikira izi: zowona, mafuta a cholesterol m'mazira ndiokwera kwambiri kuposa pafupifupi (pafupifupi 235 mg pa chidutswa chimodzi). Ndi chizolowezi cha tsiku ndi tsiku cha 300 mg, chizindikirochi chikuwoneka chowopsa.
Koma ndi mowa wamafuta, kapangidwe kake ka yolk kamaphatikizira ndi zinthu zachilengedwe zina - lecithin ndi phospholipids, zomwe sizimangoleketsa zovuta za cholesterol zomwe zimapezeka m'zinthu, komanso zimachepetsa kupanga kwachilengedwe komwe kumapangitsa ma cell a chiwindi.
Malinga ndi zomwe zaposachedwa, kudya dzira limodzi kapena awiri tsiku lililonse sikukubweretsera mavuto. Popita zaka zambiri zakafukufukuyu, zidapezeka kuti anthu omwe amadya mazira sabata lililonse mpaka 7 mpaka 10 amadwala matenda amtima wokhala ndi pafupipafupi monga maphunziro omwe adasiyira kunja izi pachakudya chawo.