Amoxiclav mapiritsi 625 malangizo ntchito

Pakati pa antimicrobial othandizira a Amoxiclav 625, kuwunika kwa odwala ndi akatswiri ndizodziwika bwino. Mankhwalawa amadziwika kuti ndi mankhwala oletsa kuponderezedwa kwambiri ndipo chifukwa chake awonedwa ponseponse. Chifukwa cha zochitika zambiri, chitetezo chogwiritsidwa ntchito mwa ana ndi kuyamwa, Amoxicillin Clavulanate pafupifupi chimakwirira gawo lonse la mankhwala othandizira kupuma ndi ma genitourinary matenda.

Kutulutsa Zinthu ndi Analogi

Mankhwala "Amoxiclav 625" amapangidwa ndi kampani yaku Slovenia Lek ndipo amaikidwa ngati mankhwala omwe mankhwala ake aminopenicillin amooticillin ndi clavulanic acid. Loyamba limagwira ngati antibayotiki, ndipo asidi amateteza kumatenda a bakiteriya. Monga gawo la mapiritsi a "Amoxiclav 625 mg" a mankhwala omwe ali ndi 500 mg ya antiotic, 125 mg ya clavulanate ndi excipients.

Mankhwala okhala ndi yogwira mankhwala amoxicillin amapezeka m'mazina ambiri. Ma analogu otetezedwa kwambiri ndi aminopenicillins otsatirawa: Amoklav, Augmentin, Flemoklav, Amklav, Farmentin, Amoksikar Plus, Augmenta, Medoklav. Palinso ma penicillin osatetezedwa, omwe ali ngati gulu la Amoxiclav: Amoxicillin, Amoxicar, Amosin, Hikontsil ndi ena. Kuchita kwawo bwino kumawerengedwa pafupifupi chimodzimodzi.

Kugwirizana kwa mankhwalawa

About ndemanga ya "Amoxiclav 625" ya akatswiri ndiosiyana kwambiri. Ichi ndi mankhwala apamwamba, imodzi mwazamankhwala ochepa amkamwa omwe ali ndi zotsatira zoyipa zochepa. Pachifukwa ichi, chimagwiritsidwa ntchito nthawi zonse momwe amoxicillin inali yoyenera. Komanso, Amoxiclav ndi woimira kukonzekera palimodzi. Imatetezedwa ndi clavulanic acid kuchokera ku penicillinase, enzyme yomwe imawononga mphete ya antibacterial lactam. Chifukwa cha chitetezo, Amoxiclav yakhala yogwira ntchito kwambiri mokhudzana ndi maselo ochepa mphamvu.

Malangizo omwe adapangidwira kukonzekera kwa Amoxiclav 625 ali ndi zisonyezo zamatenda opatsirana mankhwalawa momwe mankhwalawo amaloledwa kugwiritsidwa ntchito. Izi nthawi zambiri zimayamba kupuma, matumbo, komanso matenda amtunduwu. Mitundu yofatsa, monotherapy yokhala ndi mankhwalawa ndi yoyenera, pomwe yochepa komanso yoopsa imayenera kulandira chithandizo kuchipatala chophatikiza ndi maantibayotiki. Mwambiri, malangizowo amafotokozera zomwe zikuwonetsa kugwiritsa ntchito mankhwalawa "Amoxiclav 625 mg" motere:

• matenda a kumtunda kwa kupuma dongosolo (aakulu ndi pachimake mitundu ya tonsillitis, pharyngitis, sinusitis, otitis media),
• matenda a m'munsi kupuma thirakiti (pachimake ndi matenda a bronchitis, chibayo),
• genitourinary bacteria bacteria (pyelonephritis, urethritis, cystitis, salpingoophoritis, pelvioperitonitis, endometritis, chinzonono ndi chancroid,
• aakulu osteomyelitis,
• matenda apakhungu, kulumidwa nyama, wokhala ndi mabakiteriya achilonda,
• periodontitis.

Kwa wodwala, gwero lalikulu la chidziwitso cha Amoxiclav ndi malangizo omwe angagwiritsidwe ntchito. 625 mg ya mankhwalawa, wokhazikitsidwa katatu kwa munthu wamkulu, amatha kuchiza matenda a kupuma komwe amayamba makamaka chifukwa cha gramu. Komanso, ndimatenda opuma kwambiri, nthawi ya chithandizo nthawi zambiri imakhala masiku 5-7.

Contraindication

Chitetezo cha mankhwalawa komanso mbiri ya kawopsedwe a kalasi ya penicillin sichimapatula kukhalapo kwa contraindication.

Ali ndi mankhwala ochepa. Amalumikizidwa mwina ndi kupezeka kwa nthendayi yolimbana ndi matenda, komanso sayanjana, kapena thupi. Contraindication ndi motere:

• kukhalapo kwa zikuwonetsa za cholestatic jaundice, kuwonjezereka kwa ntchito ya aminotransferases kapena kukulitsa kwa hepatitis yoyambitsidwa ndi kugwiritsidwa ntchito koyambirira kwa Amoxiclav, ma analogues kapena oimira gulu la penicillin,
• Kulephera kwa chiwindi, mitsempha yotupa ya m'mimba, mononucleosis chifukwa cha kuchuluka kwa kuchuluka ndi kuvuta kwa zoyipa.
• Thupi lanu siligwirizana ndi mankhwalawo kapena zida zake,
• zikuwonetsa kuchitika matupi awo sagwirizana ndi mitundu yomweyo mukamamwa mankhwala ena a beta-lactam antimicrobial agents,
• contraindication osakhalitsa: pakati 3 trimester, mkaka wa m`mawere.

Chiwopsezo cha Chiwopsezo

Ngati m'mbiri ya wodwalayo muli chizindikiro cha mtundu wina wakwanuko, ndiye kuti Amoxiclav sichosankhidwa. Ngati anaphylaxis kapena edema ya Quincke yapanga poyankha kutenga mankhwala ena a beta-lactam, ndiye kuti Amoxicillin Clavulanate sayeneranso kutengedwa. Kenako woimira ma macrolides angapo omwe ali ndi mawonekedwe wofatsa kapena fluoroquinolone ndi mankhwala osankhidwa.

Mlingo regimens

Kuchuluka kwa Amoxiclav 625 mg, komwe kumafunika chithandizo, kumadalira msinkhu komanso kulemera kwa wodwalayo. Kwa matenda opuma, ndikwanzeru kupereka mpaka 2 magalamu kwa achikulire ndi magalamu 1.3 kwa achinyamata. Nthawi yomweyo, Amoxiclav mu mlingo wa 625 mg ndi wongoyerekeza komanso wachikulire. Kwa ana ochepera zaka 12, pali mankhwala omwe amakhala ndi zotsika.

Mlingo wovomerezeka kwa munthu wolemera makilogalamu oposa 40 ndipo woposa zaka 12 ndi 625 mg kawiri pa tsiku. Akuluakulu azaka zopitilira 18 amatchulidwa 625 mg katatu patsiku. Izi ndizokwanira kuchiza mapapu olimbitsa komanso opepuka, ndiye kuti, kutuluka kwa pakhungu, zotupa, komanso dongosolo loteteza khungu. M'matenda oopsa, 1000 mg (875 mg ya amoxicillin ndi 125 clavulanate) amayikidwa kawiri pa tsiku. Katatu kugwiritsa ntchito 1000 mg.

Zotsatira zoyipa

Ngakhale kupezeka kokwanira kwa njira yothandizira, pali zovuta zingapo. Amalumikizidwa ndi kusokonezeka kwamatumbo ndi m'mimba, komanso chifukwa cha kuledzera kwa thupi ndi zinthu zomwe zimawola m'maselo a bakiteriya, popeza maantibayotiki amagwira bactericidal.

Ochulukirapo (1-10%) ndi milandu ya mseru, kusanza kapena kutsekula m'mimba komwe kumachitika atagwiritsidwa ntchito ndi antimicrobial agent. Kuphatikiza apo, amawonekera atatha masiku 2 kuvomerezedwa. Mokulira kumawonjezera mwayi wa dyspepsia, kuphwanya kwamatumbo ndi matenda ena ophatikizika: kapamba chifukwa cha kuperewera, kulowa kwa chifuwa cham'mimba, chifuwa cham'mimba.

Gulu la zovuta zowonongeka (0.001-0.0001%) limaphatikizapo kuwonongeka kwa hepatic: kuchuluka kwa aminotransferases ndi chikhomo cha hepatocyte cytolysis, cholestasis ndi jaundice, leukopenia. Pankhaniyi, kusinthasintha kwa edema ya Quincke, anaphylaxis ndi urticaria sikunatchulidwe. Cholinga cha izi ndikuwonjezereka pang'onopang'ono mu kuchuluka kwa zotsatira zoyipa chifukwa cha chidwi chamwana.

Pambuyo pake, izi zidzapangitsa kuchepa kwa kufunika kwa achire a Amoxiclav. Malangizo ogwiritsira ntchito mapiritsi a 625 milligram pakadali pano aletsa kugwiritsa ntchito amayi oyamwitsa. Komabe, izi zitha kuchitika posachedwa. Kenako mudzafunika kupeza mankhwala atsopano kuchokera ku gulu la aminopenicillins ogwira ntchito mofananamo. Ndizomveka kuti mankhwala atsopano omwe adapangidwa kale ndipo akuyesedwa, komabe, kuyambitsa kwake sikunachite bwino, chifukwa Amoxiclav imakwaniritsa zofunikira za asing'anga.

Mimba komanso kuyamwa

Malinga ndi FDA, Amoxiclav ilibe teratogenic.Mapeto ake adapangidwa atapanga maphunziro a nyama, chifukwa mawonekedwe onse a mankhwalawa ali m'gulu la FDA B (USA). Komabe, chifukwa cha mantha anzeru okhathamiritsa toxosis, Amoxiclav 625 sakonda kutumikiridwa panthawi yomwe ali ndi pakati pa trimester yoyamba. Mu trimesters II ndi III, kuvomerezeka kwake ndikuloledwa.

Aminopenicillins amene amatsata amatha kulowa mkaka wa m'mawere, pomwe amapita m'matumbo a mwana wakhanda. Komabe, samayambitsa kusokonezeka kofunikira mthupi lake, ndichifukwa chake Amoxiclav 625 sangathe kuimitsidwa panthawi ya mkaka wa mkaka. Kupatula pokhapokha ngati mwana ali ndi vuto losakanikirana kapena zotupa za mucous nembanemba zomwe zimachitika pogwiritsa ntchito Amoxicillin. Kenako ndikofunikira kusiya kukakamira kwa mayi wa antimicrobial wothandizirana, kapena, chifukwa cha candidiasis ya mucous membrane, kukana kuyamwitsa.

Mbiri ya chitetezo chamankhwala

Mapiritsi a Amoxiclav 625 ali ndi mitundu yambiri ya zochizira, zomwe zimathandiza kupewa poyizoni. Zilibe zotsatira zapakati, zomwe zimatha kutengedwa ndi odwala omwe akuyendetsa magalimoto kapena njira zina zoyenda. Sizititsogolera kuti tisayiwale kukumbukira, kudziwa, chidwi kapena kuganiza.

Komabe, pali mankhwala osokoneza bongo a bongo. Milandu ngati imeneyi imakhala yosowa kwambiri ndipo imachitika pokhapokha ngati mukumwa magalamu 5 kapena kuposerapo a mankhwalawo. Zizindikiro zake ndi izi: Matenda a dyspeptic omwe amaphatikizidwa ndi kulemera pamimba, kutulutsa, kutsegula m'mimba, kusanza, komanso nthawi zina kusanza.

Pali milandu ya crystalluria yomwe imakhudzana ndi kutenga amoxicillin, nthawi zina zomwe zimayambitsa kukula kwa impso. Komabe, izi zitha kuchitika mukamamwa mankhwalawa. Mankhwalawa ndi nephroprotection ndi dialysis, omwe amachotsa amoxicillin ndi clavulanic acid m'magazi.

Njira zopewera kupewa ngozi

Kwa odwala omwe ali ndi lymphocytic leukemia kapena matenda opatsirana a mononucleosis, mankhwala Amoxiclav 625, analogues ndi ma jenetic ake sakusonyezedwa chifukwa cha mwayi waukulu wokhala ndi chotupa cha chikuku. Ndipo chifukwa chakuchepa kwa mphamvu ya njira zakulera pakamwa pa Amoxicillin, ndikofunikira kuti zithandizire kutetezedwa ku mimbayo yosafunikira ndi njira zoletsa (kondomu).

Ndi chitukuko cha kutsegula m'mimba ntchito Amoxiclav, mankhwala oletsa kupha ndi matenda amtundu wa m'mimba (hemorrhagic kapena pseudomembranous) amafunikira. Pankhaniyi, kugwiritsa ntchito Loperamide sikuvomerezeka. Komanso kugwiritsidwa ntchito kwa nthawi yayitali kwa Amoxiclav kumalimbikitsa kukula kwamagulu ambiri a tizilombo tomwe timakhala kuti timagwirizana ndi mankhwala antimicrobial. Amatha kuyambitsa matenda omwe alipo.

Zochita zodziwika za mankhwala osokoneza bongo

Allopurinol wa uricosostatic mankhwala, akatengedwa pamodzi ndi Amoxiclav, amawonjezera chiopsezo cha zotupa pakhungu. Kugwiritsa ntchito uricosuric wothandizirana ndi phenenecid, Oxyfenbutazone, Phenylbutazone, Sulfinpyrazone kapena acetylsalicylic acid kumachepetsa kutulutsa aminopenicillin (koma osati clavulanic acid), womwe umakulitsa pang'ono kuyatsidwa kwa antibayotiki mu seramu yamagazi ndikuwonjezera zotsatira zake.

Kuphatikiza kwa mankhwalawa Amoxiclav 625 mg ndi bacteriostatic antimicrobial othandizira ndi zopanda pake chifukwa chogwirizira motsatana mphamvu zawo. Kukonzekera kwina komwe kuli amoxicillin sikuyenera kuphatikizidwanso ndi bacteriostat: chloramphenicol, macrolides, tetracyclines ndi sulfonamides. Kuphatikiza ndi mabakiteriya am'magazi kumapangitsa kuti zochita za antimicrobial ziwonjezeke.

Sizomveka kugwiritsa ntchito Amoxiclav pamankhwala oletsa kubereka pamlomo chifukwa choopsa cha kuchuluka kwa prothrombin komanso kukula kwa thrombosis. Poterepa, mphamvu zakulera zimachepa kwambiri.Maantibayotiki ena ophatikizika amathandiziranso pakuchepetsa mphamvu yoletsa kubereka pakamwa.

Kugwiritsa ntchito Amoxiclav pochiza matenda opatsirana omwe amayamba chifukwa cha mankhwala a methotrexate kwambiri kumawonjezera kuwopsa kwa chotsatirachi. Izi zimawonjezera mwayi wa thrombocytopenia, leukopenia, zilonda za pakhungu, zilonda zam'mimba komanso kukokoloka. Kenako tikulimbikitsidwa kuti tisiye aminopenicillins ndikugwiritsa ntchito macrolides, ndikupitilirabe mankhwala ena ndi methotrexate.

Monga mankhwala aliwonse otakata, Amoxiclav imawonjezera mphamvu ya anticoagulants. Mankhwala othandizira omwe ali ndi "Warfarin" chifukwa cha kuletsa kwa ntchito ya bakiteriya omwe amapanga vitamini K ndi antimicrobial othandizira amatsogolera kuchepa kwa index ya prothrombin komanso kuwonjezeka kwa INR. Zotsatira zake zimakhala ngozi yayikulu yotulutsa magazi.

Zofunika za Combined Antimicrobial Therapy

Mankhwala "Amoxiclav 625", ma analogues ndi ma genetic omwe ali ndi mphamvu yowonjezera kukula kwa matenda otsekula m'mimba, ngati agwiritsidwa ntchito ndi mankhwala ena oyambitsa matenda. Magulu aliwonse othandizira limodzi ndi amoxicillin amatha kupangitsa matenda otsegula m'mimba, omwe sangathe kuthandizidwa ndi mankhwala omwe amaletsa peristalsis. Mankhwala oterowo ndi Loperamide ndi mawonekedwe ake, omwe amatsutsana ndi matenda am'mimba opatsirana. Nthawi yomweyo, matenda am'mimba omwe amayamba chifukwa cha kugwiritsa ntchito Amoxiclav amayenera kuthandizidwa ndi maantibayotiki.

Mlingo

375 mg ndi mapiritsi okhala ndi mafilimu a 625 mg

Piritsi limodzi lili

ntchito: amoxicillin monga amoxicillin trihydrate 250 mg, clavulanic acid monga potaziyamu clavulanate 125 mg (kwa 375 mg) kapena amoxicillin ngati amoxicillin trihydrate 500 mg, clavulanic acid monga potaziyamu clavulanate 125 mg (kwa 625 mg),

obwera: colloidal silicon dioxide, crospovidone, croscarmellose sodium, magnesium stearate, talc, microcrystalline cellulose,

makanema ojambula: hydroxypropyl cellulose, ethyl cellulose, polysorbate, triethyl citrate, titanium dioxide (E 171), talc.

Mapiritsi, atakulungidwa ndi chipolopolo cha zoyera kapena pafupifupi zoyera, octagonal mawonekedwe okhala ndi biconvex kumtunda, olembedwa ndi "250/125" mbali imodzi ndi "AMS" mbali inayo (kwa mulingo wa 250 mg + 125 mg).

Mapiritsi, okhala ndi film, oyera kapena pafupifupi oyera, oval okhala ndi biconvex kumtunda (kwa mlingo wa 500 mg + 125 mg).

Kutulutsa Fomu

Ipezeka mu:

• mapiritsi okutira
• ufa wa kuyimitsidwa,
• lyophilized ufa wa jakisoni.

Piritsi limodzi 375 mg limakhala ndi 250 mg ya amoxicillin ndi 125 mg ya clavulanic acid.

Piritsi ya 625 mg imakhala ndi 500 mg ya amoxicillin, 125 mg ya clavulonic acid.

Othandizira ndi:

• silicon dioxide (colloid),
• croscarmellose (mchere wa sodium),
• magnesium wakuba,
• talcum ufa
• hypopellose,
• cellulose ethyl,
• polysorbate,
• titanium dioxide
• triethyl citrate.

Mapiritsi amatayikidwa mumbale, 15 zidutswa chilichonse. Bokosi limodzi lili ndi botolo limodzi la mankhwala.

Poda yoyimitsidwa imapezeka m'mbale zamagalasi zakuda, imodzi pa bokosi. Pali supuni yoyezera. Zomwe zimaphatikizidwa kuyimitsidwa kumaphatikizapo 125 ndi 31.25 mg yogwira zinthu, motero. Pokonzekera kuyimitsidwa "Amoxiclav Forte", 5 ml yake imakhala ndi zinthu zowirikiza kawiri - 250 ndi 62,5 mg, motero. Othandizira ndi:

• citric acid
• sodium citrate
• sodium benzoate
• carmellose sodium
• silika colloid,
• sodium saccharin
• mannitol
• sitiroberi ndi zonunkhira zamtchire.

Mankhwala

Pharmacokinetics

Amoxicillin ndi clavulanic acid amasungunuka kwathunthu mu madzi amchere pH ya thupi. Zonsezi ndizoyamwa bwino pakamwa.Mulingo woyenera kumwa amoxicillin / clavulanic acid mukadzayamba kudya. Pambuyo pakamwa, bioavailability wa amoxicillin ndi clavulanic acid pafupifupi 70%. Mphamvu ya kuchuluka kwa mankhwalawa mu plasma ya zigawo zonse ziwiri ndi zofanana. Pazambiri za seramu ndizodziwikiratu zimafikira ola limodzi pambuyo pa kukhazikitsa.

Mphamvu ya amoxicillin ndi clavulanic acid mu seramu ya magazi mukamamwa mankhwala a amoxicillin / clavulanic acid ndi ofanana ndi omwe amadziwika ndi pakamwa pokhapokha ngati gawo limodzi la amoxicillin ndi clavulanic acid.

Pafupifupi 25% ya kuchuluka kwathunthu kwa clavulanic acid ndi 18% ya amoxicillin amamangiriza mapuloteni a plasma. Kuchuluka kwa magawa pakamwa pakumwa mankhwala pafupifupi 0.3-0.4 l / kg wa amoxicillin ndi 0,2 l / kg wa clavulanic acid.

Pambuyo pokonzekera mtsempha wamagazi, onse amoxicillin ndi clavulanic acid adapezeka mu chikhodzodzo, mafinya am'mimbamo, khungu, mafuta, minofu minofu, zotumphukira ndi zotumphukira zam'mimba, bile ndi mafinya. Amoxicillin amalowa bwino mu madzi a cerebrospinal.

Amoxicillin ndi clavulanic acid amawoloka placental zotchinga. Zinthu zonsezi zimadutsanso mkaka wa m'mawere.

Amoxicillin amachotsekera pang'ono mu mkodzo wofanana ndi penicillic acid wofanana ndi 10 - 25% ya mlingo woyambirira. Clavulanic acid imapangidwa m'thupi ndi kuponyera mkodzo ndi ndowe, komanso mpweya wa mpweya wothira mpweya.

Kuchulukitsa kwapakati theka la moyo wa amoxicillin / clavulanic acid ndi pafupifupi ola limodzi, ndipo kuvomerezeka kokwanira pafupifupi 25 l / h. Pafupifupi 60-70% ya amoxicillin ndi 40-65% ya clavulanic acid amachotsedwa mu mkodzo mkati mwa maola 6 atatha kumwa kamodzi pa mapiritsi a amoxicillin / clavulanic acid. Pa maphunziro osiyanasiyana, zidapezeka kuti 50-85% ya amoxicillin ndi 27-60% ya clavulanic acid amachotsedwa mkodzo mkati mwa maola 24. Kuchuluka kwacrosulanic acid kumachotsedwa pakatha maola 2 mutatha ntchito.

Kugwiritsa ntchito pamodzi kwa phenenecid kumachepetsa kutulutsidwa kwa amoxicillin, koma mankhwalawa samakhudza kutuluka kwa clavulanic acid kudzera mu impso.

Hafu ya moyo wa amoxicillin imakhala yofanana mwa ana a zaka zitatu mpaka ziwiri, komanso mwa ana achikulire ndi akulu. Popereka mankhwala kwa ana aang'ono kwambiri (kuphatikiza ana akhanda) m'milungu yoyamba ya moyo, mankhwalawa sayenera kuperekedwa kawiri patsiku, omwe amalumikizidwa ndi kusakhazikika kwa njira ya impso kwa ana. Chifukwa chakuti okalamba omwe ali ndi vutoli amatha kuvutika ndi vuto la impso, mankhwalawa ayenera kuyikidwa mosamala ku gulu la odwala, koma ngati kuli kotheka, kuyang'anira ntchito yaimpso kuyenera kuchitika.

Chilolezo chonse cha amoxicillin / clavulanic acid m'madzi am'magazi amachepetsa mwachindunji kuchepa kwa impso. Kuchepa kwa chilolezo cha amoxicillin kumanenedweratu poyerekeza ndi clavulanic acid, chifukwa kuchuluka kwa amoxicillin kumathandizidwa kudzera mu impso. Chifukwa chake, popereka mankhwala kwa odwala omwe amalephera aimpso, kusintha kwa mankhwalawa ndikofunikira kuti muchepetse kuchuluka kwa amoxicillin ndikukhalabe wofunikira clavulanic acid.

Popereka mankhwala kwa odwala omwe ali ndi vuto la chiwindi, muyenera kusamala posankha mlingo ndikuwonetsetsa ntchito ya chiwindi.

Mankhwala

Amoxicillin ndi mankhwala opanga ma cell kuchokera ku penicillin gulu (beta-lactam antiotic) lomwe limalepheretsa ma enzyme amodzi kapena angapo (omwe nthawi zambiri amatchedwa ma penicillin-binding protein) omwe amaphatikizidwa ndi biosynthesis ya peptidoglycan, yomwe ndi gawo lofunikira kwambiri mwa khoma la bakiteriya.Kuletsa kwa peptidoglycan synthesis kumayambitsa kufooka kwa khungu la cell, nthawi zambiri kumatsatiridwa ndi lysis l cell ndi cell cell.

Amoxicillin amawonongeka ndi beta-lactamases opangidwa ndi mabakiteriya osagwira, chifukwa chake zochitika za amoxicillin zokhazokha sizimaphatikizapo tizilombo tating'onoting'ono timene timatulutsa ma enzymes amenewa.

Clavulanic acid ndi beta-lactam mwapangidwe kogwirizana ndi penicillin. Imalepheretsa ma beta-lactamase, potero kuletsa kuyatsidwa kwa amoxicillin ndikukulitsa zochitika zake. Clavulanic acid yokha ilibe mphamvu yokhudza antibacterial.

Kuchulukitsa nthawi yopitilira muyeso wosachepera (T> IPC) imawerengedwa kuti ndiyo yofunika kwambiri pakuwonetsa mphamvu ya amoxicillin.

Njira ziwiri zomwe zingalimbane ndi amoxicillin ndi clavulanic acid ndi:

inactivation ndi bacteria beta-lactamases omwe saponderezedwa ndi clavulanic acid, kuphatikiza makalasi B, C ndi D.

kusintha kwa mapuloteni omangira penicillin, omwe amachepetsa kuyanjana kwa antibacterial wothandizila ku pathogen yomwe akufuna.

Kusakhudzidwa kwa mabakiteriya kapena njira ya pampu ya efflux (kayendedwe ka zinthu) kumatha kuyambitsa kapena kupitiliza kulimbana ndi mabakiteriya, makamaka mabakiteriya osagwiritsa ntchito gramu.

Mfundo za MIC zokhala amoillillin / clavulanic acid ndizomwe zimatsimikiziridwa ndi Komiti ya European for Testing of Antimicrobial Sensitivity (EUCAST).

Mapiritsi a Amoxiclav ndi ufa - malangizo ogwiritsira ntchito

Kwa ana ochepera zaka 12 - 40 mg pa kilogalamu ya kulemera kwa tsiku.
Kwa ana omwe kulemera kwawo kupitilira 40 makilogalamu, mankhwalawa amamulembera ngati munthu wamkulu.

Akuluakulu amalembedwa: Mapiritsi a 375 mg amatengedwa tsiku lililonse la 8 tsiku lililonse, mapiritsi a 625 mg maola 12 aliwonse. Popereka mankhwala othandizira odwala kwambiri, Mlingo wa 625 mg maola 8 aliwonse, kapena 1000 mg maola 12 aliwonse, amagwiritsidwa ntchito.

Tiyenera kudziwa kuti mapiritsi amatha kusiyanasiyana malinga ndi zomwe zimagwira. Chifukwa chake, simungathe kusintha piritsi la 625 mg (500 g ya amoxicillin ndi 125 g ya clavulanic acid) ndi mapiritsi awiri 375 mg (250 g of amoxicillin ndi 125 g ya clavulanic acid).

Dongosolo lotsatirali limagwiritsidwa ntchito pochiza matenda a odontogenic. Mapiritsi 375 mg amatengedwa maola 8 aliwonse, pozungulira wotchi. Mapiritsi a 625 mg pambuyo pa maola 12.

Ngati kuli kofunikira kugwiritsa ntchito mankhwalawa kuchiza odwala omwe ali ndi matenda a impso, mkodzo wa creatinine uyenera kukumbukiridwa. Odwala omwe ali ndi matenda a chiwindi amafunikira kuwunika ntchito yawo nthawi zonse.

Mphamvu yakuyimitsidwa kwa makanda ndi ana mpaka miyezi itatu. Dosing imachitika pogwiritsa ntchito kapeniki woyezera wapadera kapena supuni. Mlingo - 30 mg ya amoxicillin pa kilogalamu ya kulemera, kawiri pa tsiku.

Mumada nkhawa ndi prostatitis? Sungani ulalo

Kwa ana okulirapo kuposa miyezi itatu kwa matenda ofatsa komanso odziletsa - 20 mg / kg yolemetsa thupi, komanso matenda oopsa - 40 mg / kg. Mlingo wachiwiri umagwiritsidwanso ntchito pochiza matenda oopsa - kutupa kwa khutu lapakati, sinusitis, bronchitis, chibayo. Malangizo amaphatikizidwa ndi mankhwalawa, momwe mumakhala matebulo apadera omwe amakupatsirani kuti muwerenge molondola kuchuluka kwa mankhwalawa kwa ana.

Mlingo wovomerezeka wa ana tsiku lililonse ndi ana ndi 45 mg / kg, kwa akulu - 6 magalamu. Clavulanic acid imatha kutengedwa patsiku osaposa 600 mg kwa akulu ndi 10 mg / kg kwa ana.

Pang'ono pang'ono za mankhwalawa

Lek ndi kampani yotchuka kwambiri padziko lonse yamankhwala ku Slovenia. Amoxiclav 625 imapangidwa pano malinga ndi kusungidwa kwa miyezo yapamwamba yazoyenera muzida zonse zopanga.

Kupereka kwamtundu uliwonse wa mankhwala kumakhala ndi kuphatikiza kwa 500 mg ya mankhwala aminopenicillin amooticillin ndi 125 mg ya clavulanic acid, omwe amalepheretsa mabakiteriya okhala ndi bakiteriya, ndikuwonetsetsa mphamvu ya antibayotiki pakulimbana ndi matenda opatsirana. Othandizira nawonso ndi gawo la mankhwalawa.

Kuphimba kwamafuta piritsi kumakhala ndi chitonthozo chachikulu pakugwiritsa ntchito.

Mu mndandanda wa aminopenicillins, ma fanizo ena a mankhwala amadziwika, mwachitsanzo:

Kufotokozera kwa mafomu omasulira

Mankhwalawa amapezeka mu mawonekedwe a mapiritsi okhala ndi zoyera kapena zoyera.Mapiritsiwo ali ndi mawonekedwe owundana a biconvex.

Piritsi limodzi la 625 mg limakhala ndi 500 mg ya amoxicillin trihydrate ndi 125 mg ya clavulanic acid (mchere wa potaziyamu).

Mapiritsi amatha kupanga zitini zamapulasitiki (mapiritsi 15 aliyense) kapena matuza a aluminium a 5 kapena 7.

Mapiritsi a 1000 mg amaphatikizanso, amakhala ndi mawonekedwe osungika okhala ndi mbali zopindika. Kumbali ina mwa iwo pali zolemba za "AMS", mbali inayo - "875/125". Amaphatikizapo 875 mg ya antiotic ndi 125 mg ya clavulanic acid.

Zomwe zimagwiritsidwa ntchito

Akatswiri ambiri opapatiza amavomereza kuti mankhwala amkamwa Amoxiclav 625 ndi othandiza kwambiri pa mankhwala antimicrobial pamene amoxicillin akusonyezedwa. Chiwerengero chochepa cha zoyipa zimapangitsa kuti mankhwalawo akhale ophatikizira chida champhamvu komanso chapamwamba kwambiri polimbana ndi ma virus ndi kukula msanga kwa matenda amtundu wa m'mimba kapena matumbo ofinya kwambiri, matenda opumira nthawi zosiyanasiyana za chaka. Penicillinase - puloteni yomwe imavutitsa mphete ya antibacterial lactam, ilibe mphamvu isanakhudzidwe ndi clavulanic acid. Amoxiclav 625, mogwirizana ndi malangizo ogwiritsira ntchito, amagwiritsidwa ntchito monotherapy, komabe, pali milandu pamene chithandizo chikufunika ndi zovuta za mankhwala kuchipatala motsogozedwa mwamphamvu ndi mwamphamvu kwa ogwira ntchito azachipatala.

Monga taonera malangizo, kugwiritsa ntchito mankhwala "Amoxiclav 625", mutha kuthana ndi matenda otsatirawa:

Chogwiritsiridwa ntchito kwambiri ndi Amoxiclav 625 pochiza matenda opumira kwambiri omwe amayamba chifukwa cha aerobic gram-virus. Kutanthauza tsiku lililonse kugwiritsa ntchito mankhwalawa ndi munthu wamkulu pamenepa sipangakhale masiku 7.

Pewani kumwa ngati:

1. Pali matenda ofanana
2. Zitha kuyambitsa mavuto:
3. Mkhalidwe wakuthupi umapatula kugwiritsa ntchito mankhwala othandizira,
4. Pali chiopsezo chachikulu cha jaundice wa cholestatic,
5. Mu nthawi ya chitukuko cha chiwindi chifukwa cha ntchito Amoxiclav 625 kale,
6. Kulephera kwa hepatatic kumatha kuchitika,
7. Pamaso pa mononucleosis kapena lymphocytic leukemia,
8. Kodi muli ndi pakati kapena poyamwitsa.

Ngati chiwopsezo cha kusagwirizana ndi mtundu wa komweko chikuwonjezeka, adotolo amasankha mankhwalawo kuchokera ku ma macrolides angapo kapena fluoroquinolone.

Mankhwala othandizira

Kuchuluka kwa mankhwala omwe amagwiritsidwa ntchito kuyenera kuwerengeredwa molondola potengera zaka komanso kulemera kwa wodwala. Pankhani ya matenda opuma, odwala akulu amafunika mpaka 2 magalamu a Amoxiclav 625 chithandizo, ndi gramu 1.3 kwa achinyamata. Mankhwala ena okhala ndi Mlingo wochepetsetsa amapezeka pochiza ana osakwana zaka 12.

Kuti achepetse kukula kwa thupi la munthu wolemera kuposa 40 makilogalamu komanso wamkulu kuposa zaka 12, mulingo woyenera tsiku lililonse ndi 625 mg kawiri. Akuluakulu azaka zopitilira 18 ali ndi ufulu kulandira mlingo wa masiku atatu wa Amoxiclav 625 mg. Voliyumu yowonetsedwa imakupatsani mwayi wolimbana bwino ndi matenda apakhungu komanso ofatsa a pakhungu, genitourinary system ndi kupuma kwamthupi. Kupezeka kwa matenda oopsa kumasintha kwambiri mlingo: 1000 mg patsiku kawiri. Ndizofunikira kudziwa kuti nthawi zina kugwiritsa ntchito mankhwalawa katatu mu 1000 mg ndizovomerezeka.

Zotsatira zoyipa zomwe zingachitike

Ngakhale wodwala amatha kugwiritsa ntchito mankhwalawa "Amoxiclav 625", ndikofunikira kukumbukira zotsatirazi zoyipa za kumwa:

Kutsekula m'mimba - zotsatira zoyenera kumwa mankhwalawa

Kuchepa kwamatumbo ndi m'mimba chifukwa cha kuledzera kwa thupi ndi zinthu zomwe zimawola maselo a bakiteriya,

"Amoxiclav 625" mu trimester yoyamba ya kubereka satchulidwa, komabe, mu trimesters II ndi III, kulandiridwa kwake ndikuloledwa.

Zolemba za mankhwala

Mankhwala "Amoxiclav 625" pama mapiritsi ali ndi mankhwalawa osachiritsika ndikuchotsa poyizoni.

Mankhwalawa sakhudza kugwira ntchito kwa mtima wamanjenje, chifukwa chake, amatha kugwiritsidwa ntchito ndi odwala omwe amayendetsa magalimoto kapena makina osunthira. Kukonzekera kwa mankhwala sikumayambitsa kusokonezeka kwa chikumbumtima, kukumbukira, kuganiza kapena kuganiza.

Mtengo wa mankhwala a antimicrobial Amoxiclav 625 pama mapiritsi amasiyana pang'ono m'magawo a dziko lathu ndipo ndizovomerezeka pa bajeti ya anthu wamba achi Russia

Anastasia, wa zaka 28: Mu nthawi yophukira, banja lonse, limayamba kugwira chimfine. Chaka chino ndinatsegula nyengo yamatenda. (Zithandizo za Folk sizinathandize kwenikweni pamankhwala, ndinayenera kusintha maantibayotiki, koma sindinkafuna kutero. Koma nditatha kugwiritsa ntchito Amoksiklav ndinasintha malingaliro anga, chifukwa kuyambira pomwe ndinayamba kumwa, kwenikweni masiku angapo pambuyo pake ndinakhala ndikuwonetsetsa kuti zinthu zikuyenda bwino). Ndinalibe nthawi yovutitsa banja langa, zomwe ndine wokondwa kwambiri. Ndinatenga Amoksiklav 625 ndikugwira ntchito). Ndikadwala, tsopano ndikudziwa kuchira msanga!

Nikolay, wazaka makumi atatu ndi zinayi: Posachedwa, mpaka nthawi yonyamula kwambiri ndigalimoto mu garaja. Zikuoneka ozizira. Pofika madzulo, kufooka koteroko kunaphimba mutu. Kutentha kunalumpha, snot kuyamba. Mkazi wanga adandiwuza kuti ndiyambe kumwa mapiritsi a Amoxiclav nthawi yomweyo, pa phukusi limasonyezedwa - 625 mg. Nthawi zambiri ndimakhomera vodika ndi tsabola, zimavuta m'mawa. Ndipo pomwepo ndidaganiza zoyesa, ndikuyendetsa pati vodka? M'mawa ndinadzimva wopepuka, koma kumapeto, nditatha masiku 5 nditataya mapiritsi, kunalibe chifukwa. Tsopano ndikulangiza aliyense: mtengo wake ndi wabwinobwino komanso zochita zake.

The zikuchokera mankhwala

clavulanic acid trihydrate ndi mchere wa potaziyamu, womwe umaletsa enzyme. Ndi gulu la mankhwala

Kutulutsa FomuIpezeka mu:

• mapiritsi okutira
• ufa wa kuyimitsidwa,
• lyophilized ufa wa jakisoni.

Piritsi limodzi 375 mg limakhala ndi 250 mg ya amoxicillin ndi 125 mg ya clavulanic acid.

Piritsi ya 625 mg imakhala ndi 500 mg ya amoxicillin, 125 mg ya clavulonic acid.

Othandizira ndi:

• silicon dioxide (colloid),
• croscarmellose (mchere wa sodium),
• magnesium wakuba,
• talcum ufa
• hypopellose,
• cellulose ethyl,
• polysorbate,
• titanium dioxide
• triethyl citrate.

Mapiritsi amatayikidwa mumbale, 15 zidutswa chilichonse. Bokosi limodzi lili ndi botolo limodzi la mankhwala.

Poda yoyimitsidwa imapezeka m'mbale zamagalasi zakuda, imodzi pa bokosi. Pali supuni yoyezera. Zomwe zimaphatikizidwa kuyimitsidwa kumaphatikizapo 125 ndi 31.25 mg yogwira zinthu, motero. Pokonzekera kuyimitsidwa "Amoxiclav Forte", 5 ml yake imakhala ndi zinthu zowirikiza kawiri - 250 ndi 62,5 mg, motero. Othandizira ndi:

• citric acid
• sodium citrate
• sodium benzoate
• carmellose sodium
• silika colloid,
• sodium saccharin
• mannitol
• sitiroberi ndi zonunkhira zamtchire.

Kuphatikiza kwa amoxicillin ndi clavulanic acid ndizopadera mwanjira yake. Amoxicillin ndi maantibayotiki ena a gulu la penicillin amachititsa kufa kwa ma cell mabakiteriya pomangiriza ma cell awo. Komabe ambiri

Pogwiritsa ntchito mankhwalawa, adaphunzira kuwononga maantibayotiki pogwiritsa ntchito enzyme ya beta-lactamase. Clavulanic acid amachepetsa ntchito ya enzyme iyi, motero mankhwalawa ali ndi zochita zambiri. Amapha ngakhale mabakiteriya osagonjetsedwa ndi amoxicillin. Mankhwalawa ali ndi tanthauzo la bacteriostatic ndi bactericidal pamitundu yonse

(kusiyanasiyana ndi mitsempha yokhala ndi methicillin)

Listeria.Mabakiteriya a grram-negative amakhalanso ndi chidwi ndi amoxiclav:

• Bordetella
• brucella
• gardnerella,
• Klebsiella
• moraxella
• nsomba
• Proteus
• shigella
• clostridium ndi ena.

Mosasamala kanthu kuphatikiza ndi zakudya, mankhwalawo amalowetsedwa mthupi, kuchuluka kwa mankhwalawa kumafikiridwa mu ola loyamba mutatha kudya. Ili ndi kuthamanga kwambiri komanso kuchuluka kwa magawidwe mu thupi - m'mapapu, ma pleural, ma synovial, ma toni, gland ya prostate, minofu ndi adipose minofu, sinus, khutu lapakati. Tiziwalo tating'ono kwambiri, tomwe timatulutsa am'madzi kwambiri patatha ola limodzi tikamadutsa mu plasma. Zosafunikira zochuluka, pitani mkaka wa m'mawere. Amoxicillin amawonongedwa pang'ono mthupi, ndipo asidi wambiri wa clavulanic amapukusidwa kwambiri. Amachotsa impso. Chimbudzi chaching'ono chimachitika ndi mapapu ndi matumbo. Hafu ya moyo wokhala ndi impso wathanzi ndi maola 1-1,5. Amayamwa pang'ono m'magazi pakayamwa.
Zizindikiro

Kugwiritsa ntchito mankhwalawa mankhwala amathandizira kuchiza matenda osiyanasiyana opatsirana:

• Matenda opatsirana - matenda a sinusitis (pachimake kapena osakhazikika), kutupa pakatikati, pharyngeal abscess, bronchitis, tonsilopharyngitis, chibayo ndi ena.
• Matenda amkodzo thirakiti - cystitis, pyelonephritis, urethritis ndi ena.
• Matenda a gynecological, endometritis, kuchotsa septic, salpingitis, ndi ena.
• Kutupa kwa biliary thirakiti (cholangitis, cholecystitis).
• Zofooka za zotumphukira ndi mafupa zimakhala.
• Matenda a minofu yofewa ndi khungu (kuluma, phlegmon, matenda a bala).
• Matenda amtunduwu (chancroid, gonorrhea).
• Matenda a Odontogenic momwe tizilomboti timalowa m'thupi kudzera m'miyendo.

Mapiritsi a Amoxiclav ndi ufa - malangizo ogwiritsira ntchito

Amoxiclav amalembedwa mosiyanasiyana. Njira yoyendetsera zimadalira zaka komanso kulemera kwa wodwalayo, kuuma

zikhalidwe za impso

. Nthawi yoyenera yogwiritsira ntchito mankhwalawa ndiyamba kudya. Maphunzirowa amatenga masiku 5 mpaka 14, simungathe kuwagwiritsa ntchito nthawi yayitali.

Kwa ana ochepera zaka 12 - 40 mg pa kilogalamu ya kulemera kwa tsiku.

Kwa ana omwe kulemera kwawo kupitilira 40 makilogalamu, mankhwalawa amamulembera ngati munthu wamkulu.

Akuluakulu amalembedwa: Mapiritsi a 375 mg amatengedwa tsiku lililonse la 8 tsiku lililonse, mapiritsi a 625 mg maola 12 aliwonse. Popereka mankhwala othandizira odwala kwambiri, Mlingo wa 625 mg maola 8 aliwonse, kapena 1000 mg maola 12 aliwonse, amagwiritsidwa ntchito.

Tiyenera kudziwa kuti mapiritsi amatha kusiyanasiyana malinga ndi zomwe zimagwira. Chifukwa chake, simungathe kusintha piritsi la 625 mg (500 g ya amoxicillin ndi 125 g ya clavulanic acid) ndi mapiritsi awiri 375 mg (250 g of amoxicillin ndi 125 g ya clavulanic acid).

Dongosolo lotsatirali limagwiritsidwa ntchito pochiza matenda a odontogenic. Mapiritsi 375 mg amatengedwa maola 8 aliwonse, pozungulira wotchi. Mapiritsi a 625 mg pambuyo pa maola 12.

Ngati kuli kofunikira kugwiritsa ntchito mankhwalawa kuchiza odwala omwe ali ndi matenda a impso, mkodzo wa creatinine uyenera kukumbukiridwa. Odwala omwe ali ndi matenda a chiwindi amafunikira kuwunika ntchito yawo nthawi zonse.

Mphamvu yakuyimitsidwa kwa makanda ndi ana mpaka miyezi itatu. Dosing imachitika pogwiritsa ntchito kapeniki woyezera wapadera kapena supuni. Mlingo - 30 mg ya amoxicillin pa kilogalamu ya kulemera, kawiri pa tsiku.

Kwa ana okulirapo kuposa miyezi itatu kwa matenda ofatsa komanso odziletsa - 20 mg / kg yolemetsa thupi, komanso matenda oopsa - 40 mg / kg. Mlingo wachiwiri umagwiritsidwanso ntchito pochiza matenda oopsa - kutupa kwa khutu lapakati, sinusitis, bronchitis, chibayo. Malangizo amaphatikizidwa ndi mankhwalawa, momwe mumakhala matebulo apadera omwe amakupatsirani kuti muwerenge molondola kuchuluka kwa mankhwalawa kwa ana.

Mlingo wovomerezeka wa ana tsiku lililonse ndi ana ndi 45 mg / kg, kwa akulu - 6 magalamu. Clavulanic acid imatha kutengedwa patsiku osaposa 600 mg kwa akulu ndi 10 mg / kg kwa ana.

Kufotokozera kwa mafomu omasulira

Ufa woyimitsidwa pakamwa ndikugwiritsa ntchito ana. Mamililita asanu omalizira kuyimitsidwa ali ndi 250 mg ya amoxicillin trihydrate ndi 62,5 mg wa clavulanic acid potaziyamu wamchere. Kapena, 5 ml ikhoza kukhala ndi 125 mg ya amoxicillin ndi 31,5 mg wa clavulanic acid. Kupatsa kuyimitsidwa kukoma kosangalatsa, kumakhala ndi zinthu zotsekemera ndi zipatso. Mphamvu yakuyimitsidwa imayikidwa mumbale zagalasi zakuda. Kuchuluka kwa mabotolo ndi 35, 50, 70 kapena 140 ml. Supuni yopereka ndikuiika m'bokosi lomwe lili ndi botolo.

Mankhwalawa amapezeka mu mawonekedwe a mapiritsi okhala ndi zoyera kapena zoyera. Mapiritsiwo ali ndi mawonekedwe owundana a biconvex.

Piritsi limodzi la 625 mg limakhala ndi 500 mg ya amoxicillin trihydrate ndi 125 mg ya clavulanic acid (mchere wa potaziyamu).

Mapiritsi amatha kupanga zitini zamapulasitiki (mapiritsi 15 aliyense) kapena matuza a aluminium a 5 kapena 7.

Mapiritsi a 1000 mg amaphatikizanso, amakhala ndi mawonekedwe osungika okhala ndi mbali zopindika. Kumbali ina mwa iwo pali zolemba za "AMS", mbali inayo - "875/125". Amaphatikizapo 875 mg ya antiotic ndi 125 mg ya clavulanic acid.

Ili ndiye dzina la ufa woyimitsidwa, womwe uli ndi 5 ml 125 mg ya amoxicillin ndi 31,5 mg wa clavulanic acid. Wopezeka m'mabotolo a 100 ml, pabokosi lamakatoni okhala ndi supuni ya dosing. Mlingo ukusonyezedwa m'chigawo "Amoxiclav - malangizo ogwiritsira ntchito."

Amoxiclav 250 ("Amoxiclav Forte")

Ndiwonso ufa woyimitsa, koma uli ndi muyeso wambiri wa amoxicillin - 250 mg mu 5 ml ndi 62,5 mg wa clavulanic acid. Kuyimitsidwa kumeneku kumatchedwa Amoxiclav Forte chifukwa cha kuchuluka kwa maantibayotiki momwe amapangidwira. Mlingo ukusonyezedwa m'chigawo "Amoxiclav - malangizo ogwiritsira ntchito."

Awa ndi mapiritsi a Amoxiclav - 625 mg, okhala ndi 500 mg ya antibayotiki enieni. Kugwiritsa ntchito ndi Mlingo wofunikira zikuwonetsedwa mu gawo la "Amoxiclav malangizo ogwiritsira ntchito", ndipo kapangidwe kake ndi katundu wawo zalembedwa m'gawo "mapiritsi a Amoxiclav".

Awa ndi mapiritsi a Amoxiclav - 1000 mg, okhala ndi 875 mg wa antibayotiki weniweni, ndi 125 mg ya clavulanic acid. Kugwiritsa ntchito ndi Mlingo zikuwonetsedwa panjira ya momwe mankhwalawo amagwiritsidwira ntchito, ndipo kapangidwe kake ndi zinthu zomwe zili mgawoli "mapiritsi a Amoxiclav".

Mapiritsiwo ali ndi 500 mg ya amoxicillin ndi 125 mg ya clavulanic acid. Kugwiritsa ntchito ndi Mlingo zikuwonetsedwa panjira ya momwe mankhwalawo amagwiritsidwira ntchito, ndipo kapangidwe kake ndi zinthu zomwe zili mgawoli "mapiritsi a Amoxiclav".

Mapiritsiwo ali ndi 875 g ya amoxicillin ndi 125 mg ya clavulanic acid. Kugwiritsa ntchito ndi Mlingo zikuwonetsedwa panjira ya momwe mankhwalawo amagwiritsidwira ntchito, ndipo kapangidwe kake ndi zinthu zomwe zili mgawoli "mapiritsi a Amoxiclav".

Mapiritsi okhala ndi zipatso pompopompo amakhala ndi 500 mg ya amoxicillin ndi 125 mg ya clavulanic acid, kapena 875 mg wa amoxicillin ndi 125 mg ya clavulanic acid.

Mukamamwa mankhwalawa, pamakhala kuphwanya chiwindi komanso

(cholestatic), ngati kale mankhwalawa agwiritsidwa kale ntchito ndipo wodwalayo amakhala ndi chidwi chomwenso chimapangitsa zigawo zina za mankhwalawo, kapena ma penicillin onse.

Odwala omwe sagwirizana ndi cephalosporins, kapena pamaso pa pseudomembranous colitis, chiwindi kulephera kapena kukanika kwa aimpso, mankhwala amayatsidwa mosamala.

Odwala omwe ali ndi mononucleosis kapena lymphocytic leukemia omwe adalembedwa kale ampicillin, zotupa za mtundu wa erythematous zitha kuonedwa. Pankhaniyi, maantibayotiki ayenera kusiyidwa.

Nthawi zambiri zimakhala zosavuta kudutsa komanso kulekerera mosavuta ndi odwala. Zotsatira zoyipa zimatha kuchitika mwa odwala okalamba, komanso mwa odwala omwe amagwiritsa ntchito Amoxiclav nthawi yayitali. Nthawi zambiri, zotsatira zoyipa zimachitika pakumala kapena kumaliza chithandizo, koma nthawi zina chitukuko chake chimachitika patatha milungu ingapo mutamaliza mankhwalawa.

Matumbo oyenda. Monga lamulo, uku ndi kutsekula m'mimba, mseru, kusanza, komanso dyspepsia. Flatulence, stomatitis kapena gastritis, kusinthika kwa lilime kapena glossitis, enterocolitis ndiyofala. Nthawi ya mankhwala atamaliza kapena itatha, pseudomembranous colitis imatha - matenda omwe amayamba chifukwa cha mabakiteriya amtundu wa clostridium.

Magazi. Matendawa (kuphatikiza hemolytic), eosinophilia, kuchepa kwa maselo ambiri komanso / kapena leukocytes, agranulocytosis amathanso kuchitika.

Machitidwe amanjenje atha kumwa mankhwalawa ndi mutu, chizungulire, kukwiya, kusowa tulo, kukomoka, kusachita bwino kapena kufooka.

Chiwindi. Zizindikiro za mayeso a hepatic zimawonjezeka, kuphatikiza ntchito ya AsAT ndi / kapena AlAT, phosphatase ya alkaline ndi serum bilirubin asymptomatic kuchuluka.

Khungu. Khungu limatha kuyankha pakudya kwa amoxiclav ndi totupa, ming'oma, angioedema, erythema multiforme, poyizoni epermermal necrolysis, exfoliative dermatitis, matenda a Stevens-Johnson.

Njira yamikodzo - pali mawonekedwe a magazi mumkodzo ndi interstitial nephritis.

Ndi kugwiritsa ntchito mankhwala kwa nthawi yayitali, malungo amatha

mkamwa wamkamwa, komanso wowonekera

Amoxiclav pa mimba

Amoxiclav nthawi

ndikofunika kuti musagwiritse ntchito. Chosiyana ndi izi nthawi zomwe phindu la kumwa mankhwalawo ndiwokwera kuposa zovuta zomwe zimayambitsa. Kumwa mankhwalawa panthawi yapakati kumawonjezera chiopsezo cha necrotizing colitis mkati

Amoxiclav ya ana

Kwa ana, ufa woyimitsidwa umagwiritsidwa ntchito, wokhazikika komanso Amoxiclav Forte. Njira yakugwiritsira ntchito ikufotokozedwa mu gawo la Amoxiclav - njira yogwiritsira ntchito.

Amoxiclav ndi angina

Maantibiotic ma angina amangoperekedwa pokhapokha ngati kwambiri komanso mwamphamvu kwambiri. Amoxiclav, ngati antibayotiki wa mndandanda wa penicillin, nthawi zambiri amathandizidwa ndi tonsillitis. Kugwiritsa ntchito kwake kumawonetsedwa pokhapokha mtundu wa bakiteriya ngati utatsimikiziridwa, ndipo microflora ya pathogenic imayesedwa kuti imve chidwi ndi mankhwalawa. Mankhwala a tonsillitis mwa ana, kuyimitsidwa kumagwiritsidwa ntchito, akuluakulu - mapiritsi. Woopsa, jakisoni wa mankhwala amagwiritsidwa ntchito.

Kumbukirani kuti maantibayotiki sayenera kugwiritsidwa ntchito kwa nthawi yayitali, chifukwa izi zimawonjezera kukana kwa microflora ya pathogenic kwa iwo.

Zambiri pa zilonda zapakhosi

Kugwirizana kwina ndi mankhwala ena

• Ndiosafunika kugwiritsa ntchito nthawi yomweyo Amoxiclav ndi kukonzekera kwa anticoagulants. Izi zingayambitse kuchuluka kwa prothrombin nthawi.
• Kuchita kwa Amoxiclav ndi allopurinol kumayambitsa chiopsezo cha exanthema.
• Amoxiclav imawonjezera kawopsedwe wa metatrexate.
• Simungagwiritse ntchito onse amoxicillin ndi rifampicin - awa ndi osokoneza, ophatikizira ntchito amachepetsa mphamvu ya antibacterial onse.
• Amoxiclav sayenera kulembedwa pamodzi ndi tetracyclines kapena macrolides (awa ndi mankhwala opatsirana a bacteriostatic), komanso sulfonamides chifukwa chakuchepa kwa mphamvu ya mankhwalawa.
• Kutenga Amoxiclav kumachepetsa mphamvu zakulera m'mapiritsi.

Kuyerekeza ndi mankhwala ena Kodi Ubwino kuposa Amoxiclav? Kusankha maantibayotiki pochiza matenda aliwonse, muyenera kutsogoleredwa ndi zotsatira za kuyesa kwa microflora ya pathogenic kuti mukhale ndi chidwi ndi mankhwala enaake. Palibe nzeru kugwiritsa ntchito mankhwala omwe samapha mabakiteriya - ndiko kuti, samachiritsa. Chifukwa chake, maantibayotiki omwe microflora ya wodwala imakhudzidwa ndi thanzi imakhala yabwinoko.
Amoxiclav kapena amoxicillin?

Amoxiclav ndi mankhwala othandiza kwambiri kuposa amoxicillin, popeza tizilombo tosiyanasiyana tomwe timapanga chitetezo cha m'thupi titha kupewetsa mankhwala ndipo taphunzira kuiwononga, kuti isawonetse mphamvu yake ya bakiteriya. Kuphatikiza kwa clavulanic acid ku amoxicillin kunapangitsa kuti maantibayotiki agwire ntchito kwambiri, ndikuwonjezera zochita zake.

Amoxiclav kapena Augmentin?

Augmentin - analog ya Amoxiclav, ili ndi zinthu zomwezi.

Zambiri pazamankhwala Augmentin

Flemoxin ndi mankhwala okhala ndi amoxicillin yekhayo. Popanda clavulonic acid, imakhala ndi mawonekedwe owoneka pang'ono, chifukwa chake imagwiritsidwa ntchito pokhapokha ngati microflora ya bakiteriya ikamvetsetsa maantibayotiki.

Zambiri za Flemoxin

Amoxiclav kapena Sumamed? Kuphatikizidwa kwa Sumamed kumaphatikizapo mankhwala azithromycin, omwe ali ndi zochita zambiri. Kusankha kuyenera kuchitika pamaziko a kuwunika kwa microflora ya pathogenic pamankhwala awiriwa. Zotsatira zoyipa ndizofanana.

Zambiri pa Sumamed

Mowa umagwirizana ndi mowa Kumwa zakumwa zoledzeretsa kumachepetsa kwambiri mphamvu ya antibacterial ya mankhwala.

Ma Synonyms ndi fanizoMawu:

• Amovikomb,
• Arlet
• Baktoklav,
• Clamosar
• Verklav,
• Samalirani
• Lyclav,
• Panclave
• Ranklav,
• Rapiclav
• Toromentin
• Flemoklav,
• Mochulukitsa
• Amoxicillin + clavulanic acid (Faiser) ndi ena.

Madokotala amafufuza

Anna Leonidovna, wothandizira, Vitebsk. Amoxiclav imakhala yothandiza kwambiri pochiza matenda osiyanasiyana opuma kuposa momwe analogue, amoxicillin. Ndikupereka maphunzirowa masiku 5, kenako ndikofunikira kumwa mankhwala omwe amakonzanso microflora.

Veronika Pavlovna, dotolo. Mr. Kreshyi Rih. Mankhwalawa ali ndi vuto labwino kwambiri pakulimbana ndi bakiteriya a kumaliseche. Sichimaperekanso zovuta, nthawi yomweyo ndimapereka mankhwala a antifungal, nditatha kumwa ma probiotic kuti ndikonzenso microflora yachilendo.

Andrei Evgenievich, dotolo wa ENT, Polotsk. Kugwiritsa ntchito mankhwalawa jekeseni kumakuthandizani kuti muchepetse kuwonetsa kwa matenda oopsa komanso olimbitsa a ziwalo za ENT. Mankhwala amathandizira kutukusira khutu lapakati. Kuphatikiza apo, odwala amatenga bwino kuyimitsidwa kwa zipatso.

Ndemanga za Odwala

Victoria, Dnipropetrovsk. Kugwiritsidwa ntchito ndi adokotala pochiza matenda a tonsillitis. Anaona masiku 5. Mankhwala olimbana ndi mankhwalawa adayamba patsiku la 3 la matenda. Matendawa adachepetsa ndi wachitatu. Khosi langa linasiya kuwawa. Zinali

, adadutsa masiku awiri, atayamba kutenga ma probiotic kuti abwezeretse microflora.

Alexandra, mzinda wa Lugansk. Mankhwalawa adalembedwa ndi dokotala kuti azichiza pyelonephritis. Maphunzirowa anali masiku 7. Jekeseni wa masiku atatu - kenaka mapiritsi. Jakisoni amakhala wowawa. Komabe, kusintha kunayamba mozungulira tsiku lachinayi. Panalibe mavuto. Ndiye kamwa youma ija.

Tamara, mzinda wa Boyarka. Adandilowetsa mankhwalawa ngati mankhwalawa. Zimakhala zopweteka kwambiri, mikwingwirima idatsalira pamalo a jakisoni. Komabe, patatha sabata limodzi palibe chomwe chatsalira mu smears kuchokera kwa pathogen.

Amoxiclav ya ana

Lilia Evgenievna, Saransk. Amoxiclav (kuyimitsidwa) anathandizira chibayo mwa mwana wathu. Ali ndi zaka 3.5. Patsiku lachitatu, matumbo atayamba, dokotala adapereka mankhwala omwe amamwa atatha maphunzirowo kwa mwezi wina. Kutupa kwamapapu kunagonjetsedwa mwachangu - pa 10, mwana anali kale kumva bwino. Momwe ndikumvera, maantibayotiki onse ayenera kutsukidwa ndi kukonzekera kwa bakiteriya.

Ngati mankhwalawa amagwiritsidwa ntchito kwanthawi yayitali, ndikofunikira kuyang'anira ntchito ya chiwindi, ziwalo zopanga magazi ndi impso za wodwalayo. Ngati wodwalayo wasokoneza ntchito yaimpso, ndikofunikira kusintha mlingo kapena kuonjezera pakadali pakati Mlingo wa mankhwala. Ndikwabwino kumwa mankhwala ndi chakudya. Pankhani ya superinfection (mawonekedwe a microflora osazindikira maantibayotiki), ndikofunikira kusintha mankhwalawa. Chifukwa chakuchulukana kwa matupi a cephalosporins mwa odwala omwe ali ndi penicillin, sikofunikira kugwiritsa ntchito maantibayotiki nthawi imodzi.

Mukamamwa mankhwalawa, muyenera kumwa madzi ambiri kuti mupewe mapangidwe amkodzo wa amoxicillin.

Mukuyenera kudziwa kuti kupezeka kwa Mlingo wambiri wa maantibayotiki mthupi kumatha kupangitsa kuti shuga azigwirizana ndi mkodzo (ngati malingaliro a Benedict kapena njira ya Fleming agwiritsidwa ntchito kuti adziwe). Zotsatira zodalirika pamenepa zimapereka ntchito ya enzymatic reaction ndi glucosidase.

Popeza zotsatira zoyipa za m'magazi amanjenje ndizotheka kugwiritsa ntchito mankhwalawa, ndikofunikira kuyendetsa bwino magalimoto (magalimoto) kapena kuchita zinthu zomwe zimafunikira chidwi, kuthamanga ndi chidwi.

Amamasulidwa pa mankhwala.

Zosungirako ndi moyo wa alumali Sitolo m'malo ouma osawonekera kwa ana. Kutentha kosungira - osaposa 25 digiri. Kugwiritsa ntchito mankhwalawa atatha nthawi yawo yoletsedwa.

CHIYAMBI! Zomwe zidatumizidwa patsamba lathu ndizothandiza kapena ndizotchuka ndipo zimaperekedwa kwa omvera ambiri kuti azikambirana. Chithandizo cha mankhwala chikuyenera kuchitika kokha ndi katswiri woyenera, kutengera mbiri yachipatala ndi zotsatira za matenda.

Munkhaniyi, mutha kuwerengera malangizo ogwiritsira ntchito mankhwalawa Amoxiclav. Amapereka ndemanga kuchokera kwa alendo omwe amabwera patsamba lino - ogwiritsa ntchito mankhwalawa, komanso malingaliro a akatswiri azachipatala pakugwiritsa ntchito Amoxiclav pochita zawo. Chopempha chachikulu ndikuti muwonjezere ndemanga zanu za mankhwalawa: mankhwalawo adathandizira kapena sanathandizire kuchotsa matendawa, ndizovuta ziti zomwe zimawoneka ndi zotsatirapo zake, mwina sizinalengezedwe ndi wopanga. Analogs a Amoxiclav kukhalapo kwa mapangidwe anthawi zophatikizika. Gwiritsani ntchito mankhwalawa matenda osiyanasiyana opatsirana akuluakulu, ana, komanso pa nthawi ya bere. Kugwiritsa ntchito moledzera komanso zotsatira zomwe zingachitike mutatenga Amoxiclav.

Amoxiclav - ndi kuphatikiza kwa amoxicillin - semisynthetic penicillin wokhala ndi mawonekedwe osiyanasiyana a antibacterial zochita ndi clavulanic acid - choletsa-lactamase inhibitor chosasinthika. Clavulanic acid imapanga khola losagwirizana ndi ma enzymes amenewa ndikuwonetsetsa kukana kwa amoxicillin pazotsatira za beta-lactamases zopangidwa ndi tizilombo.

Clavulanic acid, yofanana ndi mankhwala a beta-lactam, ali ndi mphamvu yofooka ya antibacterial.

Amoxiclav ali ndi mawonekedwe osiyanasiyana a antibacterial kanthu.

Imagwira ntchito pothana ndi zovuta zomwe zimakhudzidwa ndi amoxicillin, kuphatikiza tizilombo ta beta-lactamases, incl. aerobic gram-virus bacteria, aerobic gram-negative bacteria, anaerobic gram-positive bacteria, anaerobic gram-haser ana.

Pharmacokinetics

Magawo akuluakulu a pharmacokinetic a amoxicillin ndi clavulanic acid ndi ofanana. Zonsezi zimapangidwa bwino mutatha kumwa mankhwalawo mkati, kudya sikumakhudza kuchuluka kwa mayamwidwe. Zonsezi zimadziwika ndi kuchuluka kogawika m'madzi amthupi ndi minyewa (mapapu, khutu lapakati, zotulutsa ndi zotumphukira za m'chiberekero, chiberekero, mazira, ndi zina). Amoxicillin imalowanso madzi ophatikizika a chiwindi, chiwindi, matumbo a prostate, minofu ya palatine, minofu ya minyewa, chikhodzodzo, kutsekeka kwa mphuno, malovu, kubisala kwa bronchial. Amoxicillin ndi clavulanic acid simalowa BBB ndi mauna osavulala. Amoxicillin ndi clavulanic acid amadutsa chopinga ndipo amachotseredwa mkaka wa m'mawere mosiyanasiyana. Amoxicillin ndi clavulanic acid amadziwika ndi zomanga zochepa m'mapuloteni a plasma.Amoxicillin amaphatikizidwa pang'ono, asidi clavulanic mwachidziwikire amatha kuyamwa kwambiri. Amoxicillin amachotseredwa ndi impso pafupifupi osasinthika ndi kubisala kwa tubular ndi kusefera kwa glomerular. Clavulanic acid imapukusidwa ndi kusefera kwa glomerular, mwanjira ina ya metabolites.

Zizindikiro

Matenda oyambitsidwa ndi tizilombo tating'onoting'ono tating'ono:

• matenda a chapamwamba kupuma thirakiti ndi ENT ziwalo (kuphatikizapo pachimake ndi matenda sinusitis, pachimake ndi matenda otitis TV, pharyngeal abscess, tonsillitis, pharyngitis),
• matenda am'munsi kupuma thirakiti (kuphatikizapo pachimake bronchitis ndi bakiteriya wamphamvu, matenda opha ziwalo, chibayo),
• matenda a kwamkodzo thirakiti
• matenda azamatenda
• matenda a pakhungu ndi minofu yofewa, kuphatikiza kulumidwa kwanyama ndi anthu,
• matenda a mafupa ndi osakanikirana,
• matenda am'mimba thirakiti (cholecystitis, cholangitis),
• matenda odontogenic.

Kutulutsa Mafomu

Ufa pokonzekera jekeseni wa mtsempha wa magazi (4) 500 mg, 1000 mg.

Ufa pakukonzekera kuyimitsidwa kwa makonzedwe apakamwa a 125 mg, 250 mg, 400 mg (fomu yabwino kwa ana).

Mapiritsi okhala ndi mafilimu 250 mg, 500 mg, 875 mg.

Malangizo ogwiritsira ntchito ndi mlingo

Akuluakulu ndi ana opitirira zaka 12 (kapena zopitilira 40 makilogalamu a kulemera kwa thupi): mulingo woyenera wa matenda opatsirana pang'onopang'ono ndi piritsi limodzi 250 250 + 125 mg maola 8 aliwonse kapena piritsi limodzi 500 500 + 125 mg maola 12 aliwonse, ngati ali ndi matenda oopsa ndi matenda amtundu wamapapo - 1 piritsi 500 + 125 mg maola 8 aliwonse kapena piritsi limodzi. 875 + 125 mg maola 12 aliwonse.Mapiritsi sinafotokozeredwe ana osakwana zaka 12 (ochepera 40 makilogalamu a thupi).

Mlingo wapamwamba wa tsiku ndi tsiku wa clavulanic acid (munthawi ya mchere wa potaziyamu) ndi 600 mg kwa akulu ndi 10 mg / kg yolemetsa wa ana. Mlingo wapamwamba wa tsiku ndi tsiku wa amoxicillin ndi 6 ga kwa akulu, 45 mg / kg pa thupi la ana.

Njira ya mankhwala ndi masiku 5-14. Kutalika kwa nthawi ya chithandizo akutsimikiza ndi dokotala. Kuchiza sikuyenera kupitirira masiku opitilira 14 popanda kupimidwa kachiwiri.

Mlingo wa matenda odontogenic: 1 tabu. 250 +125 mg maola 8 aliwonse kapena piritsi limodzi 500 + 125 mg maola 12 aliwonse masiku 5.

Mlingo wa kulephera kwa aimpso: kwa odwala omwe amalephera kupweteka aimpso (Cl creatinine - 10-30 ml / min), mlingo ndi tebulo limodzi. 500 + 125 mg maola 12 aliwonse, kwa odwala omwe amalephera kwambiri aimpso (creatinine Cl osakwana 10 ml / min), mlingo ndi tebulo limodzi. 500 + 125 mg maola 24 aliwonse

Zotsatira zoyipa

Zotsatira zoyipa nthawi zambiri zimakhala zofatsa komanso zosakhalitsa.

• kusowa kwa chakudya
• kusanza, kusanza,
• kutsegula m'mimba
• kupweteka m'mimba
• pruritus, urticaria, zotupa za erythematous,
• angioedema,
• anaphylactic shock,
• matumbo a vasculitis,
• dermatitis exfoliative,
• Matenda a Stevens-Johnson
• leukopenia wosinthika (kuphatikizapo neutropenia),
• thrombocytopenia
• hemolytic anemia,
• eosinophilia
• chizungulire, kupweteka mutu,
• kukomoka (kumachitika kwa odwala mkhutu aimpso ntchito akamamwa mankhwala kwambiri),
• kumverera kwa nkhawa
• kusowa tulo
• interstitial nephritis,
• khalid
• kukula kwa zamphamvu (kuphatikizapo candidiasis).

Contraindication

• Hypersensitivity ku zilizonse za mankhwala,
• Hypersensitivity m'mbiri mpaka penicillin, cephalosporins ndi mankhwala ena a beta-lactam,
• mbiri ya umboni wa cholestatic jaundice komanso / kapena chiwindi china chodwala chomwe chimayamba chifukwa chotenga amoxicillin / clavulanic acid,
• matenda mononucleosis ndi lymphocytic leukemia.

Mimba komanso kuyamwa

Amoxiclav imatha kutumikiridwa panthawi yomwe ali ndi pakati ngati pali mawonekedwe omveka.

Amoxicillin ndi clavulanic acid ang'onoang'ono amachotsedwa mkaka wa m'mawere.

Malangizo apadera

Ndi njira ya chithandizo, ntchito za magazi, chiwindi ndi impso ziyenera kuyang'aniridwa.

Odwala kwambiri mkhutu aimpso ntchito, kukonzekera koyenera wa dosing regimen kapena kuwonjezeka kwa pakati pakati pa dosing kumafunika.

Pofuna kuchepetsa chiopsezo cha zovuta m'matumbo, mankhwalawa amayenera kumwa ndi zakudya.

Kuyeserera kwa Laborator: kuchuluka kwa amoxicillin kumapereka malingaliro abodza pamkodzo wa glucose mukamagwiritsa ntchito njira ya Benedict kapena Reelling's. Enzymatic zimachitikira ndi glucosidase tikulimbikitsidwa.

Sizoletsedwa kugwiritsa ntchito Amoxiclav ndi kumwa nthawi yomweyo, chifukwa chiwopsezo cha matenda amtundu wa chiwindi pakumawamwa nthawi yomweyo chikukula kwambiri.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Palibe deta pazovuta za Amoxiclav mu Mlingo wolimbikitsidwa pa kuyendetsa galimoto kapena kugwira ntchito ndi makina.

Kuyanjana kwa mankhwala osokoneza bongo

Ndi munthawi yomweyo kugwiritsa ntchito mankhwala Amoxiclav ndi maantacididi, glucosamine, mankhwala othandizira, aminoglycosides, mayamwidwe amachepetsa, ndi ascorbic acid - ukuwonjezeka.

Ma diuretics, allopurinol, phenylbutazone, NSAIDs ndi mankhwala ena omwe amatseka kubisalira kwa tubular kumawonjezera kuchuluka kwa amoxicillin (clavulanic acid imachotsedwa makamaka ndi kusefera kwa glomerular).

Ndi munthawi yomweyo kugwiritsa ntchito Amoxiclav kumawonjezera kawopsedwe wa methotrexate.

Pogwiritsa ntchito munthawi yomweyo Amoxiclav ndi allopurinol, zochitika za exanthema zimawonjezeka.

Makonzedwe oyanjana ndi disulfiram ayenera kupewedwa.

Nthawi zina, kumwa mankhwalawa kungakulitse nthawi ya prothrombin, motere, kusamala kuyenera kugwiritsidwa ntchito popereka mankhwala anticoagulants ndi Amoxiclav.

Kuphatikiza kwa amoxicillin ndi rifampicin ndikutsutsana (pali kufooka kwa mphamvu ya antibacterial).

Amoxiclav sayenera kugwiritsidwa ntchito nthawi imodzi ndi mankhwala opatsirana a bacteriostatic (macrolides, tetracyclines), sulfonamides chifukwa kuchepa kwa mphamvu ya Amoxiclav.

Probenecid amachepetsa kupukusira kwa amoxicillin, kukulitsa kuchuluka kwake kwa seramu.

Maantibayotiki amathandizira kuchepetsa kupatsirana kwa pakamwa.

Mndandanda wa mankhwala Amoxiclav

Zofanana muzochitika zamagulu:

• Amovikomb,
• Amoxiclav Quicktab,
• Arlet
• Augmentin
• Baktoklav,
• Verklav,
• Clamosar
• Lyclav,
• Samalirani
• Panclave
• Ranklav,
• Rapiclav
• Taromentin
• Flemoklav Solutab,
• Mochulukitsa.

Popeza pali mankhwala a analogi wa yogwira mankhwala, mutha kutsatira maulalo omwe ali pansipa ndi matenda omwe amathandizira mankhwala ndikuwona mawonekedwe ofananizira achire.

Zotsatira zoyipa

Nthawi zambiri zimakhala zosavuta kudutsa komanso kulekerera mosavuta ndi odwala. Zotsatira zoyipa zimatha kuchitika mwa odwala okalamba, komanso mwa odwala omwe amagwiritsa ntchito Amoxiclav nthawi yayitali. Nthawi zambiri, zotsatira zoyipa zimachitika pakumala kapena kumaliza chithandizo, koma nthawi zina chitukuko chake chimachitika patatha milungu ingapo mutamaliza mankhwalawa.

Matumbo oyenda. Monga lamulo, uku ndi kutsekula m'mimba, mseru, kusanza, komanso dyspepsia. Flatulence, stomatitis kapena gastritis, kusinthika kwa lilime kapena glossitis, enterocolitis ndiyofala. Nthawi ya mankhwala atamaliza kapena itatha, pseudomembranous colitis imatha - matenda omwe amayamba chifukwa cha mabakiteriya amtundu wa clostridium.

Magazi. Matendawa (kuphatikiza hemolytic), eosinophilia, kuchepa kwa maselo ambiri komanso / kapena leukocytes, agranulocytosis amathanso kuchitika.

Machitidwe amanjenje atha kumwa mankhwalawa ndi mutu, chizungulire, kukwiya, kusowa tulo, kukomoka, kusachita bwino kapena kufooka.

Chiwindi. Zizindikiro za mayeso a hepatic zimawonjezeka, kuphatikiza ntchito ya AsAT ndi / kapena AlAT, phosphatase ya alkaline ndi serum bilirubin asymptomatic kuchuluka.

Khungu. Khungu limatha kuyankha pakudya kwa amoxiclav ndi totupa, ming'oma, angioedema, erythema multiforme, poyizoni epermermal necrolysis, exfoliative dermatitis, matenda a Stevens-Johnson.

Njira yamikodzo - pali mawonekedwe a magazi mumkodzo ndi interstitial nephritis.
Pogwiritsa ntchito mankhwalawa kwa nthawi yayitali, malungo, milomo yamkamwa, komanso ma feminitis owonekera.

Kugwirizana kwina ndi mankhwala ena

• Ndiosafunika kugwiritsa ntchito nthawi yomweyo Amoxiclav ndi kukonzekera kwa anticoagulants. Izi zingayambitse kuchuluka kwa prothrombin nthawi.
• Kuchita kwa Amoxiclav ndi allopurinol kumayambitsa chiopsezo cha exanthema.
• Amoxiclav imawonjezera kawopsedwe wa metatrexate.
• Simungagwiritse ntchito onse amoxicillin ndi rifampicin - awa ndi osokoneza, ophatikizira ntchito amachepetsa mphamvu ya antibacterial onse.
• Amoxiclav sayenera kulembedwa pamodzi ndi tetracyclines kapena macrolides (awa ndi mankhwala opatsirana a bacteriostatic), komanso sulfonamides chifukwa chakuchepa kwa mphamvu ya mankhwalawa.
• Kutenga Amoxiclav kumachepetsa mphamvu zakulera m'mapiritsi.

Zowonjezera

Ngati mankhwalawa amagwiritsidwa ntchito kwanthawi yayitali, ndikofunikira kuyang'anira ntchito ya chiwindi, ziwalo zopanga magazi ndi impso za wodwalayo. Ngati wodwalayo wasokoneza ntchito yaimpso, ndikofunikira kusintha mlingo kapena kuonjezera pakadali pakati Mlingo wa mankhwala. Ndikwabwino kumwa mankhwala ndi chakudya. Pankhani ya superinfection (mawonekedwe a microflora osazindikira maantibayotiki), ndikofunikira kusintha mankhwalawa. Chifukwa chakuchulukana kwa matupi a cephalosporins mwa odwala omwe ali ndi penicillin, sikofunikira kugwiritsa ntchito maantibayotiki nthawi imodzi.

Mukamamwa mankhwalawa, muyenera kumwa madzi ambiri kuti mupewe mapangidwe amkodzo wa amoxicillin.

Mukuyenera kudziwa kuti kupezeka kwa Mlingo wambiri wa maantibayotiki mthupi kumatha kupangitsa kuti shuga azigwirizana ndi mkodzo (ngati malingaliro a Benedict kapena njira ya Fleming agwiritsidwa ntchito kuti adziwe). Zotsatira zodalirika pamenepa zimapereka ntchito ya enzymatic reaction ndi glucosidase.

Popeza zotsatira zoyipa za m'magazi amanjenje ndizotheka kugwiritsa ntchito mankhwalawa, ndikofunikira kuyendetsa bwino magalimoto (magalimoto) kapena kuchita zinthu zomwe zimafunikira chidwi, kuthamanga ndi chidwi.

Amoxiclav 625 amatanthauza maantibayotiki omwe ali ndi zochita zambiri. Ndi mankhwala ophatikiza. Ndi gawo lalikulu la penicillin.

Kutulutsa mafomu ndi kapangidwe kake

Kuchokera mu:

1. Mapiritsi okhala ndi mafilimu. Zinthu zazikulu zomwe zimagwira: amoxicillin 250, 500 ndi 875 mg (zomwe zili mu mawonekedwe a amoxicillin trihydrate) ndi clavulanic acid 125 mg. Kuphatikizikako kumathandizidwa: silicon dioxide, crospovidone, sodium croscarmellose, magnesium stearate, talc. Mapiritsi amapezeka mu matuza ndi mabotolo agalasi lakuda. Phukusi la makatoni lili ndi botolo 1 kapena 1 matuza (mapiritsi 15) ndi malangizo ogwiritsira ntchito.
2. Ufa pakukonzekera kuyimitsidwa pakamwa pakukonzekera ndi kukonza yankho la jekeseni wamkati.

Zotsatira za pharmacological

Mapiritsi a Amoxiclav ndi ufa - malangizo ogwiritsira ntchito

Kwa ana ochepera zaka 12 - 40 mg pa kilogalamu ya kulemera kwa tsiku.
Kwa ana omwe kulemera kwawo kupitilira 40 makilogalamu, mankhwalawa amamulembera ngati munthu wamkulu.

Akuluakulu amalembedwa: Mapiritsi a 375 mg amatengedwa tsiku lililonse la 8 tsiku lililonse, mapiritsi a 625 mg maola 12 aliwonse.Popereka mankhwala othandizira odwala kwambiri, Mlingo wa 625 mg maola 8 aliwonse, kapena 1000 mg maola 12 aliwonse, amagwiritsidwa ntchito.

Tiyenera kudziwa kuti mapiritsi amatha kusiyanasiyana malinga ndi zomwe zimagwira. Chifukwa chake, simungathe kusintha piritsi la 625 mg (500 g ya amoxicillin ndi 125 g ya clavulanic acid) ndi mapiritsi awiri 375 mg (250 g of amoxicillin ndi 125 g ya clavulanic acid).

Dongosolo lotsatirali limagwiritsidwa ntchito pochiza matenda a odontogenic. Mapiritsi 375 mg amatengedwa maola 8 aliwonse, pozungulira wotchi. Mapiritsi a 625 mg pambuyo pa maola 12.

Ngati kuli kofunikira kugwiritsa ntchito mankhwalawa kuchiza odwala omwe ali ndi matenda a impso, mkodzo wa creatinine uyenera kukumbukiridwa. Odwala omwe ali ndi matenda a chiwindi amafunikira kuwunika ntchito yawo nthawi zonse.

Mphamvu yakuyimitsidwa kwa makanda ndi ana mpaka miyezi itatu. Dosing imachitika pogwiritsa ntchito kapeniki woyezera wapadera kapena supuni. Mlingo - 30 mg ya amoxicillin pa kilogalamu ya kulemera, kawiri pa tsiku.

Mumada nkhawa ndi prostatitis? Sungani ulalo

Kwa ana okulirapo kuposa miyezi itatu kwa matenda ofatsa komanso odziletsa - 20 mg / kg yolemetsa thupi, komanso matenda oopsa - 40 mg / kg. Mlingo wachiwiri umagwiritsidwanso ntchito pochiza matenda oopsa - kutupa kwa khutu lapakati, sinusitis, bronchitis, chibayo. Malangizo amaphatikizidwa ndi mankhwalawa, momwe mumakhala matebulo apadera omwe amakupatsirani kuti muwerenge molondola kuchuluka kwa mankhwalawa kwa ana.

Mlingo wovomerezeka wa ana tsiku lililonse ndi ana ndi 45 mg / kg, kwa akulu - 6 magalamu. Clavulanic acid imatha kutengedwa patsiku osaposa 600 mg kwa akulu ndi 10 mg / kg kwa ana.

Kufotokozera kwa mafomu omasulira

Mankhwalawa amapezeka mu mawonekedwe a mapiritsi okhala ndi zoyera kapena zoyera. Mapiritsiwo ali ndi mawonekedwe owundana a biconvex.

Piritsi limodzi la 625 mg limakhala ndi 500 mg ya amoxicillin trihydrate ndi 125 mg ya clavulanic acid (mchere wa potaziyamu).

Mapiritsi amatha kupanga zitini zamapulasitiki (mapiritsi 15 aliyense) kapena matuza a aluminium a 5 kapena 7.

Mapiritsi a 1000 mg amaphatikizanso, amakhala ndi mawonekedwe osungika okhala ndi mbali zopindika. Kumbali ina mwa iwo pali zolemba za "AMS", mbali inayo - "875/125". Amaphatikizapo 875 mg ya antiotic ndi 125 mg ya clavulanic acid.

Amoxiclav 125

Amoxiclav 250 ("Amoxiclav Forte")

Amoxiclav 500

Amoxiclav 875

Amoxiclav 625

Amoxiclav 1000

Amoxiclav Quicktab

Contraindication

Mukamamwa mankhwalawa, pakhoza kukhala kuphwanya ntchito za chiwindi ndi jaundice (cholestatic), ngati kale mankhwalawa amagwiritsidwa ntchito kale ndipo wodwalayo amakhala ndi chidwi chochulukirapo pazigawo za mankhwalawo, kapena ma penicillin onse.

Odwala omwe sagwirizana ndi cephalosporins, kapena pamaso pa pseudomembranous colitis, chiwindi kulephera kapena kukanika kwa aimpso, mankhwala amayatsidwa mosamala.

Odwala omwe ali ndi mononucleosis kapena lymphocytic leukemia omwe adalembedwa kale ampicillin, zotupa za mtundu wa erythematous zitha kuonedwa. Pankhaniyi, maantibayotiki ayenera kusiyidwa.

Zotsatira zoyipa

Nthawi zambiri zimakhala zosavuta kudutsa komanso kulekerera mosavuta ndi odwala. Zotsatira zoyipa zimatha kuchitika mwa odwala okalamba, komanso mwa odwala omwe amagwiritsa ntchito Amoxiclav nthawi yayitali. Nthawi zambiri, zotsatira zoyipa zimachitika pakumala kapena kumaliza chithandizo, koma nthawi zina chitukuko chake chimachitika patatha milungu ingapo mutamaliza mankhwalawa.

Matumbo oyenda. Monga lamulo, uku ndi kutsekula m'mimba, mseru, kusanza, komanso dyspepsia. Flatulence, stomatitis kapena gastritis, kusinthika kwa lilime kapena glossitis, enterocolitis ndiyofala. Nthawi ya mankhwala atamaliza kapena itatha, pseudomembranous colitis imatha - matenda omwe amayamba chifukwa cha mabakiteriya amtundu wa clostridium.

Magazi. Matendawa (kuphatikiza hemolytic), eosinophilia, kuchepa kwa maselo ambiri komanso / kapena leukocytes, agranulocytosis amathanso kuchitika.

Machitidwe amanjenje atha kumwa mankhwalawa ndi mutu, chizungulire, kukwiya, kusowa tulo, kukomoka, kusachita bwino kapena kufooka.

Chiwindi. Zizindikiro za mayeso a hepatic zimawonjezeka, kuphatikiza ntchito ya AsAT ndi / kapena AlAT, phosphatase ya alkaline ndi serum bilirubin asymptomatic kuchuluka.

Khungu. Khungu limatha kuyankha pakudya kwa amoxiclav ndi totupa, ming'oma, angioedema, erythema multiforme, poyizoni epermermal necrolysis, exfoliative dermatitis, matenda a Stevens-Johnson.

Njira yamikodzo - pali mawonekedwe a magazi mumkodzo ndi interstitial nephritis.
Pogwiritsa ntchito mankhwalawa kwa nthawi yayitali, malungo, milomo yamkamwa, komanso ma feminitis owonekera.

Amoxiclav pa mimba

Amoxiclav ya ana

Amoxiclav ndi angina

Kumbukirani kuti maantibayotiki sayenera kugwiritsidwa ntchito kwa nthawi yayitali, chifukwa izi zimawonjezera kukana kwa microflora ya pathogenic kwa iwo.
Zambiri pa zilonda zapakhosi

Kugwirizana kwina ndi mankhwala ena

• Ndiosafunika kugwiritsa ntchito nthawi yomweyo Amoxiclav ndi kukonzekera kwa anticoagulants. Izi zingayambitse kuchuluka kwa prothrombin nthawi.
• Kuchita kwa Amoxiclav ndi allopurinol kumayambitsa chiopsezo cha exanthema.
• Amoxiclav imawonjezera kawopsedwe wa metatrexate.
• Simungagwiritse ntchito onse amoxicillin ndi rifampicin - awa ndi osokoneza, ophatikizira ntchito amachepetsa mphamvu ya antibacterial onse.
• Amoxiclav sayenera kulembedwa pamodzi ndi tetracyclines kapena macrolides (awa ndi mankhwala opatsirana a bacteriostatic), komanso sulfonamides chifukwa chakuchepa kwa mphamvu ya mankhwalawa.
• Kutenga Amoxiclav kumachepetsa mphamvu zakulera m'mapiritsi.

Yerekezerani ndi mankhwala ena

Kodi bwino kuposa amoxiclav?

Amoxiclav kapena amoxicillin?

Amoxiclav kapena Augmentin?

Amoxiclav kapena Flemoxin?

Amoxiclav kapena Sumamed?

Kuyenderana ndi mowa

Ma Synonyms ndi fanizo

Madokotala amafufuza

Anna Leonidovna, wothandizira, Vitebsk. Amoxiclav imakhala yothandiza kwambiri pochiza matenda osiyanasiyana opuma kuposa momwe analogue, amoxicillin. Ndikupereka maphunzirowa masiku 5, kenako ndikofunikira kumwa mankhwala omwe amakonzanso microflora.

Veronika Pavlovna, dotolo. Mr. Kreshyi Rih. Mankhwalawa ali ndi vuto labwino kwambiri pakulimbana ndi bakiteriya a kumaliseche. Sichimaperekanso zovuta, nthawi yomweyo ndimapereka mankhwala a antifungal, nditatha kumwa ma probiotic kuti ndikonzenso microflora yachilendo.

Andrei Evgenievich, dotolo wa ENT, Polotsk. Kugwiritsa ntchito mankhwalawa jekeseni kumakuthandizani kuti muchepetse kuwonetsa kwa matenda oopsa komanso olimbitsa a ziwalo za ENT. Mankhwala amathandizira kutukusira khutu lapakati. Kuphatikiza apo, odwala amatenga bwino kuyimitsidwa kwa zipatso.

Ndemanga za Odwala

Victoria, Dnipropetrovsk. Kugwiritsidwa ntchito ndi adokotala pochiza matenda a tonsillitis. Anaona masiku 5. Mankhwala olimbana ndi mankhwalawa adayamba patsiku la 3 la matenda. Matendawa adachepetsa ndi wachitatu. Khosi langa linasiya kuwawa. Panali matenda otsegula m'mimba, ndinadutsa patangotha ​​masiku awiri, nditayamba kumwa mankhwala okonzanso kuti ndikonzenso microflora.

Alexandra, mzinda wa Lugansk. Mankhwalawa adalembedwa ndi dokotala kuti azichiza pyelonephritis. Maphunzirowa anali masiku 7. Jekeseni wa masiku atatu - kenaka mapiritsi. Jakisoni amakhala wowawa. Komabe, kusintha kunayamba mozungulira tsiku lachinayi. Panalibe mavuto. Ndiye kamwa youma ija.

Tamara, mzinda wa Boyarka. Adandilowetsa mankhwalawa ngati mankhwalawa. Zimakhala zopweteka kwambiri, mikwingwirima idatsalira pamalo a jakisoni. Komabe, patatha sabata limodzi palibe chomwe chatsalira mu smears kuchokera kwa pathogen.

Amoxiclav ya ana

Zowonjezera

Ngati mankhwalawa amagwiritsidwa ntchito kwanthawi yayitali, ndikofunikira kuyang'anira ntchito ya chiwindi, ziwalo zopanga magazi ndi impso za wodwalayo.Ngati wodwalayo wasokoneza ntchito yaimpso, ndikofunikira kusintha mlingo kapena kuonjezera pakadali pakati Mlingo wa mankhwala. Ndikwabwino kumwa mankhwala ndi chakudya. Pankhani ya superinfection (mawonekedwe a microflora osazindikira maantibayotiki), ndikofunikira kusintha mankhwalawa. Chifukwa chakuchulukana kwa matupi a cephalosporins mwa odwala omwe ali ndi penicillin, sikofunikira kugwiritsa ntchito maantibayotiki nthawi imodzi.

Mukamamwa mankhwalawa, muyenera kumwa madzi ambiri kuti mupewe mapangidwe amkodzo wa amoxicillin.

Mukuyenera kudziwa kuti kupezeka kwa Mlingo wambiri wa maantibayotiki mthupi kumatha kupangitsa kuti shuga azigwirizana ndi mkodzo (ngati malingaliro a Benedict kapena njira ya Fleming agwiritsidwa ntchito kuti adziwe). Zotsatira zodalirika pamenepa zimapereka ntchito ya enzymatic reaction ndi glucosidase.

Popeza zotsatira zoyipa za m'magazi amanjenje ndizotheka kugwiritsa ntchito mankhwalawa, ndikofunikira kuyendetsa bwino magalimoto (magalimoto) kapena kuchita zinthu zomwe zimafunikira chidwi, kuthamanga ndi chidwi.

Amoxiclav 625 amatanthauza maantibayotiki omwe ali ndi zochita zambiri. Ndi mankhwala ophatikiza. Ndi gawo lalikulu la penicillin.

Dzinalo

Dzina la mankhwalawa ku Latin ndi Amoksiklav.

Amoxiclav 625 amatanthauza maantibayotiki omwe ali ndi zochita zambiri.

Kutulutsa mafomu ndi kapangidwe kake

Kuchokera mu:

1. Mapiritsi okhala ndi mafilimu. Zinthu zazikulu zomwe zimagwira: amoxicillin 250, 500 ndi 875 mg (zomwe zili mu mawonekedwe a amoxicillin trihydrate) ndi clavulanic acid 125 mg. Kuphatikizikako kumathandizidwa: silicon dioxide, crospovidone, sodium croscarmellose, magnesium stearate, talc. Mapiritsi amapezeka mu matuza ndi mabotolo agalasi lakuda. Phukusi la makatoni lili ndi botolo 1 kapena 1 matuza (mapiritsi 15) ndi malangizo ogwiritsira ntchito.
2. Ufa pakukonzekera kuyimitsidwa pakamwa pakukonzekera ndi kukonza yankho la jekeseni wamkati.

Zotsatira za pharmacological

Amoxicillin amakhudza ma protein ambiri opanda gramu komanso gram - omwe amakhudzidwa ndi penicillin. Mchitidwewo umatengera kuponderezedwa kwa kaphatikizidwe ka peptidoglycan. Ndiye maziko a makoma a mabakiteriya. Nthawi yomweyo, mphamvu yamakoma am'nyumba imachepa, kuyamwa mwachangu ndi kufa kwa maselo onse a pathogenic kumachitika.

Amoxiclav imakhudzanso tizilombo toyambitsa matenda ambiri a gramu-negative ndi gramu.

Chifukwa Popeza amoxicillin imawonongeka motsogozedwa ndi ena a beta-lactamases, mawonekedwe a machitidwe a mankhwalawa sakukhudzana ndi mabakiteriya omwe amapanga lactamases.

Clavulanic acid ndi zoletsa zamphamvu kwambiri za beta-lactamase. M'mapangidwe ake, amafanana ndi ma penicillin. Mwakutero, chiwonetsero cha zochita za mankhwalawo chimafikiranso ku tizilombo tating'onoting'ono tomwe timapanga ma nonchromosomal beta-lactamases.

Pharmacokinetics

Zinthu zomwe zimagwira ntchito ndizoyamwa. Mafuta abwino amakhala ngati mumamwa mankhwalawa musanadye. Mafuta ambiri omwe amagwira ntchito m'magazi amawonekera pambuyo pa maola awiri ndi atatu. Zigawo zogwira ntchito zimatha kupezeka mu ziwalo zambiri komanso minyewa yambiri, mumadzi amniotic komanso synovial.

Kuthekera kumangiriza kumaproteni amwazi ndikochepa. Metabolism imachitika m'chiwindi. Mankhwalawa amachotseredwa ndi impso. Nthawi ya theka la moyo ili pafupifupi ola limodzi.

Pakati pa antimicrobial othandizira a Amoxiclav 625, kuwunika kwa odwala ndi akatswiri ndizodziwika bwino. Mankhwalawa amadziwika kuti ndi mankhwala oletsa kuponderezedwa kwambiri ndipo chifukwa chake awonedwa ponseponse. Chifukwa cha zochitika zambiri, chitetezo chogwiritsidwa ntchito mwa ana ndi kuyamwa, Amoxicillin Clavulanate pafupifupi chimakwirira gawo lonse la mankhwala othandizira kupuma ndi ma genitourinary matenda.

Mankhwala Okhala Pamalo a Pharmacy

Amamasulidwa pa mankhwala.

Kodi Amoxiclav ndi zingati? Mtengo wapakati pama pharmacies umatengera mtundu wa kumasulidwa:

• Mtengo Mapiritsi a Amoxiclav 250 mg + 125 mg pafupifupi 200 ma ruble a 15 ma PC. Gulani maantibayotiki 500 mg + 125 mg ikhoza kukhala yamtengo wapatali pa 360 - 400 rubles kwa ma 15 pcs. Kodi mapiritsi ndi angati? 875 mg + 125 mgzimatengera malo ogulitsa. Pafupifupi, mtengo wawo ndi 420 - 470 rubles kwa 14 ma PC.
• Mtengo Amoxiclav Quicktab 625 mg - kuchokera ku ma ruble 420 a ma PC 14.
• Mtengo wa kuyimitsidwa Amoxiclav ya ana - 290 ma ruble (100 ml).
• Mtengo Amoxiclav 1000 mg ku Ukraine (Kiev, Kharkov, etc.) - kuchokera ku 200 h scrollnias 14 zidutswa.

Mankhwala

Kuphatikiza kwa amoxicillin ndi clavulanic acid ndizopadera mwanjira yake. Amoxicillin ndi maantibayotiki ena a gulu la penicillin amachititsa kufa kwa ma cell mabakiteriya pomangiriza ma cell awo. Komabe, mabakiteriya ambiri aphunzira kuwononga maantibayotiki mothandizidwa ndi ensau ya beta-lactamase panthawi yogwiritsira ntchito mankhwalawa.

Clavulanic acid amachepetsa ntchito ya enzyme iyi, motero mankhwalawa ali ndi zochita zambiri. Amapha ngakhale mabakiteriya osagonjetsedwa ndi amoxicillin. Mankhwalawa ali ndi tanthauzo la bacteriostatic ndi bactericidal pamitundu yonse ya streptococci (kupatulapo michere yolimbana ndi methicillin), echinococcus, ndi listeria.

Mabakiteriya a grram-negative amakhalanso ndi chidwi ndi amoxiclav:

• Bordetella
• brucella
• gardnerella,
• Klebsiella
• moraxella
• nsomba
• Proteus
• shigella
• clostridium ndi ena.

Mosasamala kanthu kuphatikiza ndi zakudya, mankhwalawo amalowetsedwa mthupi, kuchuluka kwa mankhwalawa kumafikiridwa mu ola loyamba mutatha kudya.

Zizindikiro zogwiritsidwa ntchito

Amoxiclav ndi mankhwala opatsirana omwe amayambitsidwa ndi tizilombo tosiyanasiyana tomwe tili ndi matenda otsatirawa:

1. Matenda a biliary thirakiti (cholangitis, cholecystitis).
2. Mafupa ndi mafupa ofunikira matenda.
3. Matenda a pakhungu ndi minofu yofewa (impetigo, phlegmon, erysipelas, abscess, dermatoses yachiwiri yopatsirana).
4. Osteomyelitis, meningitis, sepsis ndi endocarditis.
5. Matenda a ziwalo za ENT, kupuma ndi kwapamwamba kupumira thirakiti (pharyngitis, tonsillitis, sinusitis ndi otitis media mu pachimake komanso matenda osakanikirana, chifuwa chachikulu cha chifuwa cham'mimba, chibayo, chifuwa chachikulu cha chifuwa chamkati ndi chifuwa chachikulu cha chifuwa cham'mimba.

Kugwiritsa ntchito Amoxiclav kumathandiza kupewa matenda operewera komanso kuchiza matenda a postoperative.

Mimba komanso kuyamwa

Amoxiclav mimba itha kugwiritsidwa ntchito ngati zomwe zikuyembekezeredwa zikuchuluka kuposa zomwe zingavulaze fetus. Kugwiritsa ntchito Amoxiclav koyambirira kwa mimba ndikosayenera.

2 trimester ndi 3 trimester ndizofunikira kwambiri, koma ngakhale panthawiyi mlingo wa Amoxiclav pa nthawi yoyembekezera uyenera kuchitika mosamala kwambiri. Amoxiclav yoyamwitsa osapereka mankhwala, popeza magawo a mankhwala amalowerera mkaka wa m'mawere.

Malangizo ogwiritsira ntchito Amoxiclav

Malangizo ogwiritsira ntchito akuwonetsa kuti mapiritsi Amkosiklav Akuluakulu ndi ana opitirira zaka 12 (kapena onenepa>> makilogalamu 40) at matenda ofatsa kapena olimbitsa sankha 1 tabu. (250 mg + 125 mg) maola 8 aliwonse kapena 1 tabo. (500 mg + 125 mg) maola 12 aliwonse, ngati matenda oopsa komanso matenda opatsirana thirakiti - 1 tabu. (500 mg + 125 mg) maola 8 aliwonse kapena 1 tabo. (875 mg + 125 mg) maola 12 aliwonse