Insulin

Masiku ano ku Russia oposa 10 ml a anthu omwe ali ndi matenda a shuga amalembetsedwa. Matendawa amatuluka motsutsana ndi maziko a kusowa kwa insulin komwe kumachitika mu njira za metabolic.

Kwa odwala ambiri, insulin tsiku lililonse imawonetsedwa kwa moyo wonse. Komabe, masiku ano pamsika wazachipatala zoposa 90% yazokonzekera zonse za insulin sizipangidwa mu Russian Federation. Kodi izi zikuchitika chifukwa chiyani, chifukwa msika wopanga insulin ndiwopindulitsa kwambiri komanso umalemekezedwa?

Masiku ano, kupanga kwa insulin ku Russia mwakuthupi ndi 3.5%, ndipo mwa ndalama - 2%. Ndipo msika wonse wa insulin ukuyerekeza madola 450-500 miliyoni. Mwa kuchuluka kumeneku, 200 miliyoni ndi insulin, ndipo ndalama zotsalazo zimagwiritsidwa ntchito pozindikira (pafupifupi miliyoni 100) ndi mapiritsi a hypoglycemic (130 miliyoni).

Opanga Ma insulin

Kuyambira 2003, mbewu ya insulin Medsintez idayamba kugwira ntchito ku Novouralsk, pomwe lero imapanga pafupifupi 70% ya insulini yotchedwa Rosinsulin.

Kupanga kumachitika mnyumba 4000 m2, yomwe imakhala ndi 386 m2 chimbudzi. Komanso, mtengowo uli ndi malo oyeramo ukhondo D, C, B ndi A.

Wopanga amagwiritsa ntchito ukadaulo wamakono komanso zida zaposachedwa kuchokera kumakampani odziwika odziwika. Izi ndi zida za ku Japan (EISAI) zaku Germany (BOSCH, SUDMO) ndi zida zaku Italy.

Mpaka mu 2012, zinthu zofunika pakupanga insulin zidapezeka kunja. Koma posachedwa, a Medsintez, adapanga mtundu wake wa mabakiteriya ndikutulutsa mankhwala ake omwe amatchedwa Rosinsulin.

Kuyimitsidwa kumapangidwa m'mabotolo ndi makatiriji amitundu itatu:

1. P - njira yothandizira kusintha majini a anthu. Kugwiritsa ntchito pambuyo pa mphindi 30. pambuyo makonzedwe, nsonga ya kugwira ntchito imagwera pa maola 2-4 pambuyo jekeseni ndipo kumatenga mpaka maola 8.
2. C - insulin-isophan, yopanga sc management. Zotsatira za hypoglycemic zimachitika pambuyo pa maola 1-2, kuphatikiza kwakukulu kumafikiridwa pambuyo pa maola 6-12, ndipo kutalika kwa zotsalazo kumatenga mpaka maola 24.
3. M - anthu a magawo awiri a Rosinsulin a sc sc. Kuchepetsa mphamvu ya shuga kumachitika pakatha mphindi 30, ndipo kuchuluka kwambiri kumachitika maola 4 mpaka 12 ndipo kumatenga mpaka maola 24.

Kuphatikiza pa mitundu iyi ya Mlingo, Medsintez amatulutsa mitundu iwiri ya zolembera za syinsulin za Rosinsulin - zapamwamba komanso zosinthika. Ali ndi njira yawoyokhayo yomwe imakupatsirani mwayi kuti mubwezereni mlingo wapitawo ngati sunayikiridwe momwe ungafunikire.

Rosinsulin ali ndi ndemanga zambiri pakati pa odwala ndi madokotala. Amagwiritsidwa ntchito ngati pali matenda a shuga 1 kapena mtundu 2, ketoacidosis, chikomokere kapena gestational matenda ashuga. Odwala ena amati atayambitsidwa, amalumpha m'magazi a shuga, ena odwala matenda ashuga, m'malo mwake, amatamandanso mankhwalawa, ndikutsimikizira kuti amakupatsirani mwayi wokulamulira glycemia.

Komanso, kuyambira 2011, chomera choyamba chopanga insulin chidayambitsidwa ku Oryol Region, chomwe chimachita mkombero wathunthu, ndikupanga zolembera zodzala ndi zotsekemera. Ntchitoyi idakhazikitsidwa ndi kampani yapadziko lonse Sanofi, yomwe imagulitsa kwambiri mankhwala omwe amachiza matenda a shuga.

Komabe, mbewuyo siipanga zinthuzo zokha. Mwanjira youma, thupilo limagulidwa ku Germany, pambuyo pake makristasi amunthu, mawonekedwe ake ndi mbali zina zothandizira zimaphatikizidwa kuti apeze kuyimitsidwa kwa jekeseni. Chifukwa chake, kupanga kwa insulin yaku Russia ku Orel kumachitika, pomwe ma insulin amakonzekera mwachangu komanso nthawi yayitali amapangidwa, mtundu womwe umakwaniritsa zofunikira zonse za nthambi ya Germany.

WHO ikuvomereza kuti mayiko omwe ali ndi anthu opitilira 50 miliyoni, azikonza okha mahomoni. Izi zikuthandizira odwala matenda ashuga kuti asakhale ndi zovuta kugula insulin.

Kuphatikiza apo, insulin imapangidwa ndi Geropharm, mtsogoleri wopanga mankhwala opangidwa ndi majini ku Russia. Kupatula apo, wopanga yekhayo ndi amene amapanga zinthu zapakhomo m'njira zamankhwala ndi zinthu.

Mankhwalawa amadziwika ndi munthu aliyense yemwe ali ndi matenda ashuga. Izi zikuphatikiza Rinsulin NPH (mphamvu yapakatikati) ndi Rinsulin P (zochita zazifupi). Kafukufuku adachitidwa kuti athe kuwunika momwe ndalamazo zimagwirira ntchito, pomwe panali kusiyana kwakukulu pakati pa kugwiritsa ntchito mankhwala a insulin ndi mankhwala akunja.

Chifukwa chake, odwala matenda ashuga amatha kudalira insulin yaku Russia popanda kuda nkhawa ndi thanzi lawo.