Insuman Rapid

Wopanga - Sanofi-Aventis (France), Sanofi

Mutu: Insuman® Rapid GT, Insuman® Rapid GT

Zopangidwa: 1 ml ya njira yopanda mbali ya jakisoni ili ndi 100 IU ya insulin ya anthu.
Omwe amathandizira: m-cresol, sodium dihydrogen phosphate dihydrate, glycerol, sodium hydroxide, hydrochloric acid, madzi a jakisoni.

Machitidwe Insuman Rapid GT imakhala ndi insulin, yofanana mu insulin ya anthu komanso yopezeka ndi ma genetic engineering. Kutsitsa kwa shuga kumachitika msanga, mkati mwa mphindi 30, ndikufikira pakatha maola 1-4 mutatha kugwiritsa ntchito mankhwalawa. Zotsatira zimatha kwa maola 7-9. Insuman Rapid GT ikhoza kusakanikirana ndi ma insulin onse a anthu kuchokera ku Hoechst Marion Roussel, kupatula ma insulin omwe amafunsidwa kuti ayendetse pampu.

Zisonyezero zogwiritsidwa ntchito: Insulin-wodwala matenda a shuga. Insuman Rapid GT imawonetsedwa pochiza matenda ashuga komanso ketoacidosis, komanso kuti akwaniritse zolipiritsa za metabolic odwala omwe ali ndi matenda osokoneza bongo a m'mbuyomu -, intra -, komanso nthawi ya postoperative.

Njira yogwiritsira ntchito: Insuman Rapid GT nthawi zambiri imaperekedwa kwa mphindi 15-20 asanadye chakudya. Mgwirizano wamankhwala mankhwala amaloledwa. Tsamba la jakisoni liyenera kusinthidwa nthawi iliyonse. Insuman Rapid GT imatha kutumikiridwa kudzera mu mankhwalawa a hyperglycemic coma ndi ketoacidosis, komanso kukwaniritsa kufotokozera kwa kagayidwe kachakudya ka pre-, intra- komanso postoperative nyengo kwa odwala omwe ali ndi matenda osokoneza bongo. Insuman Rapid GT sigwiritsidwe ntchito mitundu yosiyanasiyana ya mapampu a insulini (kuphatikizira omwe amaikidwira), momwe amaumbira silicone.

Zotsatira zoyipa: Nthawi zina atrophy kapena hypertrophy ya adipose minofu imatha kuchitika malo a jekeseni, omwe amatha kupewedwa ndikusintha malo a jekeseni nthawi zonse.

Nthawi zina, kufupika pang'ono kumatha kupezeka pamalowo jakisoni, ndikusowa ndikupitilira mankhwala. Ngati erythema yofunika ikakhazikitsidwa, limodzi ndi kuyabwa ndi kutupa, ndikufalikira mwachangu mpaka pamalo a jakisoni, komanso zotsatira zina zovuta pazigawo za mankhwala (insulin, m-cresol), ndikofunikira kudziwitsa dokotala mwachangu, monga nthawi zina Kuchita kotereku kukhoza kuwononga moyo wa wodwalayo.

Kusintha kwakukulu kwa Hypersensitivity kumachitika kawirikawiri. Amathanso kuphatikizidwa ndi chitukuko cha angioedema, bronchospasm, kugwa kwa magazi komanso kusowa kwa anaphylactic. Hypersensitivity reaction imafunikira kukonza mwachangu pakanthawi kovomerezeka ndi insulin komanso kukhazikitsidwa kwa njira zoyenera zadzidzidzi.

Mwina kupangika kwa ma antibodies ku insulin, komwe kungafune kusintha kwa mlingo wa insulin. Ndiwothekanso kusungidwa kwa sodium komwe kumayamba chifukwa cha kutupa kwa minofu, makamaka mukamaliza kumwa mankhwalawa.

Zoyipa: Hypersensitivity reaction insulin kapena zilizonse zothandiza za mankhwala, pokhapokha ngati insulin yofunikira. Zikatero, kugwiritsa ntchito Insuman Rapid GT kumatheka pokhapokha pakumuyang'anirani mosamala ndipo ngati kuli kotheka, kuphatikiza ndi anti-allergen.

Zochita Zamankhwala: Kuchepetsa mphamvu ya insulin kumatha kuwonedwa limodzi ndi insulin ndi corticotropin, corticosteroids, diazoxide, heparin, isoniazid, barbiturates, nicotinic acid, phenolphthalein, phenothiazine, phenytoin, diuretics, danazrogen, estrogen, estrogen. zotulutsa. Odwala omwe amalandila insulin ndi clonidine, reserpine kapena mchere wa lithiamu, zonse zimafooketsa komanso zomwe zimapangitsa kuti ntchito ya insulin iwoneke. Pentamidine imatha kuyambitsa hypoglycemia kenako hyperglycemia. Kumwa mowa kumatha kuyambitsa hypoglycemia kapena kuchepetsa shuga wochepa wokhala m'magazi kuti akhale woopsa. Kulekerera kwa mowa kwa odwala omwe amalandira insulin kumachepetsedwa. Mitundu yovomerezeka ya zakumwa ziyenera kutsimikiziridwa ndi dokotala. Uchidakwa wambiri, komanso kugwiritsa ntchito mankhwala osokoneza bongo mopitirira muyeso, umatha kukhudza glycemia. Ma Beta-blockers amawonjezera chiopsezo cha hypoglycemia ndipo, pamodzi ndi othandizira ena achifundo (clonidine, guanethidine, reserpine) amatha kufooketsa kapena ngakhale kufinya chiwonetsero cha hypoglycemia.

Mimba ndi kuyamwa: Chithandizo cha Insuman Rapid GT ziyenera kupitilizidwa pa nthawi yapakati. Pa nthawi yoyembekezera, makamaka pambuyo pa trimester yoyamba, kuwonjezereka kwa insulin kuyenera kuyembekezeredwa. Komabe, pambuyo pobadwa, kufunika kwa insulin nthawi zambiri kumatsika, komwe kumabweretsa chiwopsezo chachikulu cha hypoglycemia. Panthawi yoyamwitsa, palibe malamulo oletsa insulin. Komabe, kusintha kwa mlingo ndi kadyedwe kungafunikire.

Malo osungirako: Sungani kutentha kwa + 2 ° C mpaka + 8 ° C. Pewani kuzizira, popewa kulumikizana mwachindunji ndi botolo ndi zipupa za chipinda chaulere kapena chosungira pozizira.

Chosankha: Mochenjera, mankhwalawa amasankhidwa kwa odwala omwe ali ndi vuto laubwino wa m'magazi molingana ndi mtundu wa ischemic komanso mitundu yayikulu ya matenda a mtima a ischemic. Kufunika kwa insulin kungasinthe mukasinthira mtundu wina wa insulini (mukachotsa insulin ya nyama kuchokera ku Insuman Rapid, mlingo umachepetsedwa), ndikusintha kwa zakudya, kutsegula m'mimba, kusanza, kusintha kwa chizolowezi chochita zolimbitsa thupi, matenda a impso, chiwindi, ndulu ya pituitary, chithokomiro England, kusintha kwa malo a jekeseni. Wodwalayo ayenera kudziwitsidwa za zomwe zimachitika mu vuto la hypoglycemic, za zizindikiro zoyambirira za kukomoka kwa matenda ashuga komanso kufunika kofotokozera dokotala za kusintha kulikonse pamatenda ake.

Kutengera ndi chithunzi cha chipatala, wodwalayo amatenga mankhwala osiyanasiyana.

Pazinthu zomwe zimafuna chithandizo cha insulin, jakisoni wa hypoglycemic ndi mankhwala. Imodzi mwa mankhwalawa ndi Insuman Rapid GT.

Makhalidwe wamba

Insuman Rapid ndi mankhwala opangira matenda a shuga. Amapezeka mu mawonekedwe amadzimadzi ndikugwiritsa ntchito jakisoni.

Muzochita zamankhwala, imagwiritsidwa ntchito ndi mitundu inanso ya insulin. Amasankhidwa kuti akhale ndi matenda ashuga amtundu 1 komanso mtundu wa matenda ashuga wa 2 osagwira mapiritsi ochepetsa shuga, tsankho lawo kapena zotsutsana.

Homoni amakhala ndi vuto la hypoglycemic. Kuphatikizika kwa mankhwalawa ndi insulin yaumunthu ndi 100% solubility yochepa. Thupi limapezeka mu labotale ndi genetic engineering.

Sungunuka insulini - yogwira mankhwala. Zotsatirazi zidagwiritsidwa ntchito ngati chowonjezera: m-cresol, glycerol, madzi oyeretsedwa, hydrochloric acid, sodium hydroxide, sodium dihydrogen phosphate dihydrate.

Mankhwala

Insuman amachepetsa shuga. Zimatengera mankhwala okhala ndi nthawi yofulumira komanso yochepa.

Zotsatira zake zikuyembekezeka theka la ola jakisoni atatha mpaka maola 7. Kuzindikira kwakukulu kumawonedwa pa ora la 2 pambuyo pothandizidwa ndi subcutaneous.

Chomwe chimagwira chimagwira ma cell receptor kuti apange insulin receptor zovuta. Zimatsutsa kaphatikizidwe wama michere ofunikira ndikuti timalimbikitse njira zamagetsi. Zotsatira zake, kuyamwa ndi kuyamwa kwa glucose ndi thupi kumakulitsidwa.

• kumapangitsa kaphatikizidwe wa mapuloteni,
• zimalepheretsa kuwonongeka kwa zinthu
• timaletsa glycolenolysis ndi glyconeogeneis,
• timapititsa patsogolo mayendedwe ndi mayamwidwe a potaziyamu,
• Amasintha kaphatikizidwe wamafuta achilengedwe m'chiwindi ndi zimakhala,
• Imachepetsa kuwonongeka kwa mafuta,
• bwino zoyendera ndi mayamwidwe amino acid.

Zizindikiro ndi contraindication

Mankhwalawa amalembedwa motere:

• DM 1 (fomu yodalira insulin) ndi DM 2,
• zochizira zovuta kwambiri,
• kuthetsa matenda a shuga,
• kulandira malipiro opatsirana pokonzekera ndi pambuyo pa opareshoni.

Hormoni sinafotokozedwe motere:

• aimpso / chiwindi kulephera,
• kukana kwachangu,
• stenosis of coronary / ubongo mitsempha,
• tsankho la mankhwala,
• anthu omwe ali ndi matenda oyanjana,
• anthu omwe amapitilira retinopathy.

Zofunika! Ndi chisamaliro chachikulu, odwala matenda ashuga okalamba ayenera kumwedwa.

Malangizo ogwiritsira ntchito

Kusankha ndi kusintha kwa mankhwalawa kumatumizidwa payekhapayekha. Dotolo amamutsimikizira kuchokera kuzowonetsa shuga, kuchuluka kwa zochita zolimbitsa thupi, mkhalidwe wa kagayidwe kazachilengedwe. Wodwalayo amapatsidwa malangizo poyesa kusintha kwa glucose.

Mlingo wa tsiku ndi tsiku wa mankhwalawa, poganizira kulemera kwake, ndi 0,5 IU / kg.

Hormoni imayendetsedwa kudzera m'mitsempha, intramuscularly, subcutaneally. Njira yogwiritsira ntchito subcutaneous kwambiri. Jakisoni amachitika mphindi 15 asanadye.

Ndi monotherapy, pafupipafupi kayendetsedwe ka mankhwala amakhala pafupifupi katatu, nthawi zina amatha kufikira kangapo patsiku. Tsamba la jakisoni limasintha nthawi ndi nthawi mkati mwake. Kusintha kwa malo (mwachitsanzo, kuchokera pamanja mpaka pamimba) kumachitika pambuyo pofunsa dokotala. Kwa subcutaneous makonzedwe a mankhwala, tikulimbikitsidwa kugwiritsa ntchito cholembera.

Zofunika! Kuyamwa kwa zinthu kumasiyana malinga ndi jakisoni malo.

Mankhwalawa akhoza kuphatikizidwa ndi insulin yayitali.

Maphunziro a kanema wa syringe-cholembera insulin

Kusintha kwa Mlingo

Mlingo wa mankhwalawa ungasinthidwe milandu:

• ngati moyo ukusintha
• kuchuluka kwa chidwi ndi ntchito yogwira,
• kusintha kwa odwala
• mukamasintha kuchokera ku mankhwala ena.

Nthawi yoyamba mutasintha chinthu china (mkati mwa masabata awiri), kuyendetsa bwino shuga kumalimbikitsidwa.

Kuchokera pamitengo yapamwamba yamankhwala ena, ndikofunikira kusinthana ndi mankhwalawa moyang'aniridwa ndi achipatala.

Mukasintha kuchokera ku nyama kupita ku insulin yaumunthu, kusintha kwamankhwala kumachitika.

Kuchepetsa kwake kumafunikira pagulu lotsatira la anthu:

• shuga woyika kale pamankhwala,
• kumwa mankhwala mosamala kwambiri,
• makonzedwe a kupangika kwa dziko la hypoglycemic.

Malangizo apadera ndi odwala

Mimba ikachitika, chithandizo cha mankhwala sichimaleka. Chidacho sichidutsa placenta.

Ndi mkaka wa m`mawere, palibe zoletsedwa. Chowonadi chachikulu ndichakuti insulin dosing ikusinthidwa.

Pofuna kupewa kukhudzika kwa hypoglycemic, chithandizo cha okalamba omwe ali ndi mankhwalawa chimachitika mosamala.

Anthu omwe ali ndi vuto la chiwindi / impso amasinthira ku Insuman Rapid ndikusintha mlingo woyang'aniridwa ndi katswiri.

Kutentha kwa njira yovulazidwa kuyenera kukhala 18-28ºº. Insulin imagwiritsidwa ntchito mosamala mu matenda opatsirana pachimake - kusintha kwa mlingo kumafunika pano. Mukamamwa mankhwalawo, wodwalayo sapatula mowa. Zitha kuyambitsa hypoglycemia.

Zofunika! Makamaka chidwi ndi kumwa mankhwala ena. Zina mwazo zimatha kuchepetsa kapena kuwonjezera mphamvu ya Insuman.

Mukamamwa mankhwalawa, wodwalayo ayenera kumvetsera mosamala kusintha kwina kulikonse. Izi ndizofunikira kuti chizindikiritso cha nthawi yake chizindikiritso cha hypoglycemia chichitike.

Kuwunikiranso kwambiri zamagulu a glucose kumalimbikitsidwanso. Chiwopsezo cha hypoglycemia chogwiritsidwa ntchito ndi mankhwalawa chimakhala chachikulu mwa anthu omwe ali ndi shuga yochepa. Wodwala nthawi zonse azikhala ndi glucose 20 g.

Mosamala kwambiri, tengani:

• ndimankhwala amodzimodzi,
• likasamutsidwa kupita ku insulin ina,
• Anthu omwe amakhala ndi shuga
• okalamba
• anthu omwe amapanga pang'onopang'ono hypoglycemia,
• ndi matenda amisala.

Zindikirani! Mukasinthira ku Insuman, kuunika kwa kulekerera kwamankhwala kumachitika. Mlingo wochepa wa mankhwalawa umalowetsedwa m'njira zina. Kumayambiriro kwa makonzedwe, kuwukira kwa hypoglycemia kumatha kuoneka.

Zotsatira zoyipa ndi bongo

Izi zotsatirazi zoyipa zimasiyanitsidwa ndi makonzedwe:

Pakakhala mankhwala osokoneza bongo, wodwalayo amatha kutsitsa shuga mpaka otsika. Ndi mawonekedwe ofatsa, 15 g shuga ayenera kumwedwa.

Fomu yayikulu ya kukomoka, kutuluka kwa chikumbumtima kumafuna kuyambitsidwa kwa glucagon (intramuscularly). Mwinanso kuyambitsa kwa dextrose (kudzera m'mitsempha).

Pambuyo kukhazikika kwa mkhalidwe wa wodwalayo, ndikofunikira kumwa mankhwala osungirako okwanira. Kwa nthawi yayitali atachotsa zizindikiro za hypoglycemia, kuwunikira zomwe zofunikira pakufunika, popeza kuwonetseredwa kwachiwiri ndikotheka. Mwapadera, wodwalayo amagonekedwa m'chipatala kuti apenye.

Kuchita ndi mankhwala ena

Popanda upangiri wa dokotala, kugwiritsa ntchito mitundu inanso ya mankhwala osavomerezeka sikulimbikitsidwa. Amatha kuchulukitsa kapena kuchepetsa mphamvu ya insulin kapena kupangitsa kuti pakhale zovuta.

Kutsika kwa mphamvu ya mahomoni kumawonedwa ndikugwiritsira ntchito njira zakulera, ma glucocorticosteroids mahomoni (progesterone, estrogen), diuretics, mankhwala angapo a antipsychotic, adrenaline, mahomoni a chithokomiro, glucagon, barbiturates.

Kukula kwa hypoglycemia kumatha kuchitika limodzi ndi mankhwala ena othandizira odwala matenda ashuga. Izi zikugwira ntchito pa maantibayotiki a sulfonamide, Mao inhibitors, acetylsalicylic acid, fibrate, testosterone.

Mowa ndi mahomoni amachepetsa shuga mpaka pamavuto, amachititsa hypoglycemia. Mlingo wovomerezeka ndi dokotala. Muyeneranso kusamala pakumwa mankhwala oletsa - - kudya kwawo mopitirira muyeso kumakhudza kwambiri shuga.

Pentamidine imatha kuyambitsa zochitika zosiyanasiyana - hyperglycemia ndi hypoglycemia. Mankhwala amatha kupweteketsa mtima. Makamaka mwa anthu omwe ali pachiwopsezo.

Zindikirani! Alumali moyo wa yankho mu syringe cholembera si zoposa mwezi. Tsiku la kudya koyamba kwa mankhwala liyenera kudziwika.

Mankhwala ozindikiritsa (ofananitsa fomu yotulutsira komanso kupezeka kwa gawo lomwe limagwira ntchito) akuphatikiza: Actrapid Hm, Vosulin-R, Insuvit N, Rinsulin-R, Humodar, Farmasulin N. Mankhwalawa amaphatikizapo insulin ya anthu.

Chikhumbo cha munthu chokhala ndi moyo wathanzi, kuletsa kugwiritsa ntchito zinthu zovulaza, kuchita masewera olimbitsa thupi komanso kusapezeka kwa zizolowezi zoyipa ndizofunikira kwambiri kuti pakhale thanzi laumunthu nthawi zambiri. Komabe, nthawi zina, mosiyana ndi malingaliro aliwonse, munthu amene amagwiritsa ntchito bwino thanzi lake mosamala, amakumana ndi vuto lalikulu la metabolic. Kodi zingachitike bwanji ngati munthu sanamwe, sanamwe mowa mopitirira muyeso, kupewa nkhawa ndikuchita masewera olimbitsa thupi? Cholinga chake, mwatsoka, chagona mu chibadwa chamtsogolo, chomwe ndicho chofunikira kudziwa pamenepa, umboni womwe ungakhale matenda a matenda a shuga 1. Kodi chodabwitsa cha matenda awa ndi chiyani ndipo ndi makina ake amakula?

Kodi matenda ashuga ndi chiani?

Mtundu woyamba wa matenda a shuga ndi matenda omwe amayamba chifukwa cha kufa kwa maselo ena omwe amapanga insulini ya mahomoni mu kapamba. Kutha kwa maselo ndi kuchepa kwa insulini kumayambitsa vuto lalikulu la metabolic njira ndi hyperglycemia.

Pankhaniyi, wodwalayo akhoza kumva zotsatirazi:

Matendawa, osapezeka pa nthawi yake, amatha kutsogolera impso, mtima, kudula miyendo ngakhale kufa. Ichi ndichifukwa chake ndikofunikira kwambiri kuti munthu agwiritse matendawa ndikangofunika kuti ayambe kulandira chithandizo munthawi yake.

Kodi ndichifukwa chiyani insulin ndi yofunika kwambiri kwa thupi?

Popeza matenda amtunduwu amawonekera motsutsana ndi kusowa kwa insulin, ndiye kuti chithandizo chamankhwala chiyeneranso kugwirizananso ndi kubwezeretsanso kuchepa kwa timadzi ta m'thupi totere. Komabe, poyambira ndikofunikira kumvetsetsa kuti ntchito yake ndi yotani?

Ntchito zomwe amathetsa ndi izi:

• Kuwongolera kuwonongeka kwa glucose, komwe ndi gwero lalikulu la zakudya zamafupa am'mimba ndi ma neurons aubongo.
• Phatikizani kulowerera kwa glucose kudzera m'makoma a minofu ya minofu.
• Kusintha kukula kwa mapangidwe a mafuta ndi mapuloteni, kutengera zosowa za thupi.

Popeza insulini ndiye hormone yokhayo yomwe imagwira ntchito zosiyanasiyana komanso zosiyanasiyana, ndiyofunikira kwambiri m'thupi la munthu. Ichi ndichifukwa chake ndi matenda ashuga, wodwalayo amakakamizidwa kutenga chinthu chomwe mawonekedwe ake ali pafupi ndi timadzi timeneti. Mankhwalawa amapulumutsa wodwalayo pakukula kwa ziwalo zamkati ndi mitsempha yamagazi.

Mitundu ya insulin

Kusiyana kwakukulu pakati pa kufananizira kwa insulin ya anthu masiku ano ndi zifukwa izi:

• Zomwe mankhwalawa amapangidwa.
• Kutalika kwa mankhwalawa.
• Mlingo wa kuyeretsedwa kwa mankhwalawa.

Mwa kapangidwe kake, kukonzekera kumatha kugawidwa ngati ndalama zomwe zimaperekedwa kuchokera ku ng'ombe, zomwe nthawi zambiri zimayambitsa mavuto ndi chifuwa, kuchokera ku nkhumba ndikupezeka ndi genetic engineering. Mankhwalawa amaphatikizapo, mwachitsanzo, Germany Insulin Rapid GT.

Malinga ndi nthawi yowonekera, mankhwalawa amagawidwa m'mitundu yotere:

• Insulin yochepa, yomwe imaperekedwa kotala la ola limodzi asanadye, kuti ifanane ndi kukula kwa mahomoni mwa munthu wathanzi atatha kudya. Ndalamazi ndi monga Insulin Insuman Rapid.
• Yaitali, yomwe imayenera kutumikiridwa kamodzi kapena kawiri pa tsiku, kuti athe kutsata kupangika kwa mahomoni.

Nthawi zambiri, mitundu yonse iwiri ya mahomoni imaperekedwa kwa wodwala kuti akwaniritse zofunikira za thupi tsiku ndi tsiku. Komabe, kwa anthu omwe sangathe kuwongolera mkhalidwe wawo chifukwa cha ukalamba kapena matenda amisala, muyezo woyeserera wa mankhwala umaperekedwa. Wodalirika komanso wowonetsetsa kusintha kwa mkhalidwe wake, munthu amatha kuwerengera payekha mlingo wa Short Insulin Rapid.

Zomwe amamwa mankhwalawo

Kumwa mankhwala osokoneza bongo kumathandizira wodwala kuti azitha kukonza yekha zakudya, osadalira kwambiri zakudya komanso zochita za tsiku ndi tsiku. Kuti muchite izi, ndikofunikira kuwerengera moyenera kuchuluka kwa chakudya komanso kuchuluka kwa shuga m'magazi musanadye.

Kulandila kwa Insulin Insuman Rapid GT kumatha kusintha kwambiri moyo wa wodwalayo, chifukwa zimapangitsa kuti muzitha kuganizira za mtundu wa moyo wa munthu, chakudya chake.

Njira yogwiritsira ntchito mankhwalawa ndi muyezo, komanso mawonekedwe a kuvomereza ndi contraindication, ayenera kuphunziridwa mosamala malinga ndi malangizo a Insulin Rapid, komanso kukambirana ndi dokotala. Chofunikanso kwambiri ndikuti wodwalayo athe kuwerengetsa moyenera mankhwalawo.

Insuman Rapid GT ndi mankhwala okhala ndi insulin yocheperapo ya anthu omwe amagwiritsidwa ntchito pochiza matenda osokoneza bongo kapena zovuta zake.

Kodi mawonekedwe a Insuman Rapid GT ndi mafomu ake ndi chiyani?

Mankhwala Insuman Rapid GT amapangidwa mwanjira yankho lomveka bwino. Imaperekedwa m'mak cartridge, syringe penseli kapena m'mabotolo. Kugulitsa kumalamulidwa ndi udokotala.

Kodi ntchito ya Insuman Rapid GT ndi chiyani?

Insuman Rapid GT ndi insulin yochepa. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa ndizofanana ndi mahomoni amunthu omwe amapangidwa ndi islet zida za kapamba. M'mafakitale, gawo lomwe limagwiritsidwa ntchito ndi mankhwalawa limapangidwa ndikuyambitsa mitundu yapadera yamtundu wa BK12 wa bacterium yodziwika bwino - Escherichia coli.

Insulin yopangidwa mu thupi la munthu, komanso ma genetic engineering, imatha kulimbikitsa kusintha kwa anabolic, komanso njira zoletsa za catabolic. Mothandizidwa ndi chinthu ichi, kayendedwe ka glucose kupita ku minofu kumakulitsidwa, komwe kumapangitsa kuti glycogen apangidwe minofu ya minofu kapena ma cell a chiwindi. Kuphatikiza apo, njira zomwe zimapangira kupanga adipose minofu (lipogeneis) zimayendetsedwa.

Kachiwiri, insulini imachepetsa mphamvu pazomwe zimapangidwa ndi glucose synthesis kuchokera kuzinthu zina, makamaka kuchokera ku minofu ya adipose (gluconeogeneis), yomwe imachepetsa shuga.

Simungathe kunyalanyaza zovuta zamaproteni kagayidwe. Mothandizidwa ndi insulin, kuyenda kwa ma amino acid m'chipinda kumawonjezera, zomwe zimapangitsa njira za anabolic kupangira mapuloteni.

Pambuyo subcutaneous makonzedwe, hypoglycemic zotsatira zimayamba pambuyo 30 mphindi. Kwambiri achire zotsatira amapangidwa 1 mpaka 4 maola ntchito. Mphamvu ya mankhwalawa imatha kwa maola 7 mpaka 9.

Kodi zikuwonetsa chiyani kugwiritsa ntchito Insuman Rapid GT?

Kukhazikitsidwa kwa Insuman Rapid GT ndikotheka pamaso pa matenda otsatirawa:

Mtundu uliwonse wa matenda ashuga ofuna insulin
Kuthana ndi zovuta za matenda a shuga mwanjira ya ketoacidosis kapena chikomokere,
Kulimbitsa odwala omwe ali ndi matenda ashuga atatha kuchitapo kanthu opaleshoni.

Ndikukukumbutsani kuti chithandizo chokwanira cha matenda ashuga sichingatheke popanda kuyang'aniridwa ndi katswiri wazodziwa. Ndi endocrinologist wokhayo yemwe ayenera kupereka mankhwalawa ndikuwunika mphamvu ya mankhwalawa.

Kodi zotsutsana za Insuman Rapid GT ndi ziti?

Kugwiritsa ntchito mankhwalawa ndikosavomerezeka pamaso pa zinthu zotsatirazi:

Mikhalidwe iriyonse yamatsenga,
Kusalolera kwamunthu aliyense pachinthu chilichonse chogulitsa.

Contraindication wothandizirana: kukalamba, matenda a chiwindi ndi impso, matenda a m'mitsempha, chotupa chamkati, ngozi yowonjezera retinopathy.

Kodi ntchito ndi Mlingo wa Insuman Rapid GT ndi ziti?

Njira yoyendetsera, komanso mlingo weniweni wa mankhwalawa imatsimikiziridwa ndi katswiri, ndipo zimatengera zinthu zingapo: kuchuluka kwa glucose, kudya ndi zochitika zolimbitsa thupi, mtundu wa zochita, zaka, kulemera kwa thupi ndi zina zotero.

Mankhwalawa ayenera kuthandizidwa kupatula mphindi 10 mpaka 15 asanadye. Tsambalo la jakisoni liyenera kusinthidwa pafupipafupi, apo ayi mapangidwe ophatikizika am'mimba (zisindikizo) kapena zochitika za dystrophic ndizotheka.

Pakukhazikitsa mankhwala, kutsogolo kwa khoma lam'mimba kapena gawo la ntchafu nthawi zambiri amasankhidwa. Momwe makonzedwe a mankhwalawa ayenera kuvomerezedwera ndi katswiri, popeza kufalikira kwa jakisoni kungasinthe kuchuluka kwa kuchiritsika kwa achire.

Overdose wa Insuman Rapid GT

Ngati bongo, kupuma mwachangu ndi palpitation, kufooka, tinnitus, "kuwuluka" pamaso pa maso, nseru, kusanza, nkhawa yayikulu, mwina kumverera kwa njala, nthawi zina kugunda kwamphamvu, kumangidwa kwa kupuma, komanso kupunduka kwa minofu ya mtima, kukomoka komanso ngakhale kufa. .

Chithandizo chimatengera wodwala. Ndi kuuma pang'ono, shuga amatha kusintha pogwiritsa ntchito zakudya zomwe zili ndi shuga wokwanira.

Woopsa milandu, mankhwala othandizira amafunikira mwa njira yoyambitsira mayankho a glucose komanso njira zina zothandizira.

Zotsatira zoyipa za Insuman Rapid GT ndi chiyani?

Nthawi zambiri, mawonekedwe am thupi lawo amawonekera mwa mawonekedwe a bronchospastic phenomena, angioedema, anaphylactic reaction, ndi mawonekedwe a khungu.

Zotsatira zina zoyipa: edema, kuchepa kwa magazi, kusokonezeka kowoneka kosiyanasiyana, mawonekedwe a dystrophic m'dera loyang'anira.

Momwe mungasinthire Insuman Rapid GT, ndi ma analogi ati?

Mankhwala Actrapid HM, Rinsulin R, Biosulin R, Human insulin, Ryzodeg, Rosinsulin R, Humulin Regular, Gensulin R, Gansulin R, kuwonjezera, Insulin ya anthu, Actrapid, Vozulim-R, komanso Insuran R ndi fanizo.

Tidasanthula mankhwala a Insuman Rapid GT, malangizo ogwiritsira ntchito mankhwalawa. Kwakukulu, matenda a shuga ndi njira yapadera pamoyo, kuwonjezera pa kugwiritsa ntchito mankhwalawa, amawerengedwa kuti amachepetsa zakudya zamagulu a chakudya kuchokera kuzakudya, zolemba zolimbitsa thupi, kuyendera kwa nthawi ndi nthawi kwa katswiri ndikuwonetsetsa kuchuluka kwa shuga m'magazi.

Mlingo ndi makonzedwe

Kusankhidwa kwa mlingo wa insulin mwa wodwala kumachitika ndi dokotala payekha, kutengera zakudya, mulingo wakuchita zolimbitsa thupi. Mlingo wa insulin umatsimikizika molingana ndi kuchuluka kwa shuga m'magazi, komanso pamaziko a kuchuluka kwa zochitika zolimbitsa thupi ndi mkhalidwe wa metabolism ya carbohydrate. Chithandizo cha insulin chimafuna kudziphunzitsa koyenera kwa wodwala. Dokotala amayenera kupereka malangizo ofunikira kangati kuti azindikire kuchuluka kwa shuga m'magazi ndipo, mwina, mkodzo, ndikuwapatsanso malangizo oyenera osintha zakudya kapena machitidwe a insulin. Mlingo wamba wa insulin tsiku lililonse umachokera ku 0,5 mpaka 1.0 ME pa kilogalamu ya thupi la wodwalayo, ndipo 40-60% ya mlingo umagwera insulin yaumunthu yokhala nthawi yayitali. Posintha kuchokera ku insulin ya nyama kupita ku insulin ya anthu, kuchepetsedwa kwa insulin kungafunike. Kusintha kuchokera ku mitundu ina ya insulin kupita ku mankhwalawa kutha kuchitika kokha moyang'aniridwa ndi achipatala. Makamaka kuyang'anira mkhalidwe wa kagayidwe kazachilengedwe ndikofunikira mu masabata oyambilira pambuyo pa kusintha kumeneku.

Insuman Rapid GT nthawi zambiri imaperekedwa kwa mphindi 15-20 asanadye chakudya. Mgwirizano wamankhwala mankhwala amaloledwa. Tsamba la jakisoni liyenera kusinthidwa nthawi iliyonse. Kusintha kwa jekeseni (mwachitsanzo, kuyambira pamimba mpaka ntchafu) kuyenera kuchitika pokhapokha mukaonana ndi dokotala. Insuman Rapid GT imatha kutumikiridwa kudzera mu mankhwalawa a hyperglycemic coma ndi ketoacidosis, komanso kukwaniritsa kufotokozera kwa kagayidwe kachakudya ka pre-, intra- komanso postoperative nyengo kwa odwala omwe ali ndi matenda osokoneza bongo. Insuman Rapid GT sigwiritsidwe ntchito mitundu yosiyanasiyana ya mapampu a insulini (kuphatikizira omwe amaikidwira), momwe amaumbira silicone. Osasakaniza Insuman Rapid GT ndi insulin ya ndende ina (mwachitsanzo, 40 IU / ml ndi 100 IU / ml), ndi insulini yoyambira nyama kapena mankhwala ena. Gwiritsani ntchito mayankho omveka okha, opanda khungu la Insuman Rapid GT popanda zozizwitsa zilizonse. Kumbukirani kuti kuchuluka kwa insulini mu vial ndi 100 IU / ml, kotero muyenera kugwiritsa ntchito syringes zapulasitiki zopangidwira insulin. Syringe siyenera kukhala ndi mankhwala ena aliwonse kapena zotsalira zake. Pamaso gawo loyambirira la insulin kuchokera pambale, chotsani kapulasitiki (kukhalapo kwa kapuyo ndi umboni wa vial wosatsutsana). Njira yothetsera jakisoni iyenera kukhala yowonekera komanso yopanda utoto.

Asanatenge insulini kuchokera ku vial, mpweya wofanana ndi mankhwala omwe amaperekedwa ndi insulin umayamwa mu syringe ndikujowina mu vial (osalowa madzi). Kenako vala yokhala ndi syringe imasinthidwa mozungulira ndi syringe ndipo kuchuluka kwa insulini kumatengedwa. Pamaso jakisoni, chotsani thovu lakumanzere mu syringe. Khungu limatengedwa pamalo a jakisoni, singano imayikidwa pansi pakhungu, ndipo insulin imayamwa pang'onopang'ono. Pambuyo pa jekeseni, singano imachotsedwa pang'onopang'ono ndipo tsamba lamalowo limakanikizidwa ndi swab ya thonje kwa masekondi angapo. Tsiku lokhala ndi insulin kit kuchokera pa vial iyenera kulembedwa pa cholembera cha vial. Mutatsegula mabotolo amatha kusungidwa pa kutentha osaposa + 25 ° C kwa masabata anayi pamalo otetezedwa ku kuwala ndi kutentha.

Zolemba zogwiritsira ntchito

Ngati vuto la glycemic likulephera kapena ngati matendawa ali ndi vuto la hyper- kapena hypoglycemia, musanaganize zosintha muyezo wa insulin, onetsetsani kuti mwalamulira insulin, onetsetsani kuti insulin ili ndi njira yolimbikitsira ndi zina zonse zomwe zingakhudze zotsatira za insulin. Popeza kuperekera kwa munthawi yomweyo mankhwala angapo (onani gawo la "Kuyanjana ndi Mankhwala Ena") kungafooketse kapena kukulitsa mphamvu ya Hypoglycemic ya mankhwala a Insuman® Rapid GT, palibe mankhwala ena omwe ayenera kumwedwa panthawi yomwe amagwiritsa ntchito popanda chilolezo chadokotala.

Hypoglycemia. Hypoglycemia imachitika ngati mlingo wa insulin uposa kufunika kwake. Chiwopsezo cha kukhala ndi hypoglycemia ndi chachikulu pamayambiriro a chithandizo cha insulin, mukasinthira kukonzekera kwina kwa insulin, mwa odwala omwe ali ndi shuga yayitali m'magazi. Monga ndi ma insulin onse, chisamaliro chapadera chiyenera kutengedwa ndikuwunika kwambiri kuchuluka kwa shuga m'magazi omwe odwala hypoglycemic episode angakhale ndi vuto lapadera la matenda, monga odwala omwe ali ndi vuto lalikulu la mitsempha kapena matenda a mitsempha (chiwopsezo cha mtima kapena matenda a m'magazi a hypoglycemia), akulimbikitsidwa. , komanso odwala omwe ali ndi proliferative retinopathy, makamaka ngati sanachite nawo mankhwala opatsirana pogwiritsa ntchito mankhwala a laser, popeza ali ndi chiopsezo chocheperako amaurosis (kwathunthu khungu) ndi chitukuko cha hypoglycemia.

Pali zizindikiro ndi zodwala zina zomwe ziyenera kuwonetsa kwa wodwala kapena ena za kukhala ndi hypoglycemia. Izi zimaphatikizapo thukuta lomwe limakulirakulira, chinyezi pakhungu, tachycardia, kusokonezeka kwa mtima, kuchuluka kwa magazi, kupweteka pachifuwa, kunjenjemera, nkhawa, njala, kugona, kusokonezeka kwa tulo, mantha, kukhumudwa, kusazolowereka, zosadziwika bwino, nkhawa, paresthesia mkamwa ndi kuzungulira pakamwa, kutsekeka kwa khungu, kupweteka mutu, kusokonekera kwa kayendedwe ka kayendedwe, komanso kuchepa kwa minyewa yamitsempha yamagazi (kufooka kwa mawu ndi masomphenya, zizindikiro zakuwala) ndi zomveka zachilendo. Ndi kuchepa kwakukulu kwa ndende ya glucose, wodwalayo amatha kulephera kudziletsa komanso ngakhale kuzindikira. Zikatero, kuzizira ndi chinyezi pakhungu kumatha kuonedwa, ndipo kupweteka kumawonekeranso. Chifukwa chake, wodwala aliyense yemwe ali ndi matenda a shuga omwe amalandila insulin ayenera kuphunzira kuzindikira zizindikiro zomwe ndi chizindikiro cha kukhala ndi hypoglycemia. Odwala omwe nthawi zonse amayang'anira kuchuluka kwa shuga m'magazi samatha kukhala ndi hypoglycemia. Wodwala yekha amatha kukonza kuchepa kwa kuchuluka kwa shuga m'magazi omwe adazindikira mwa kudya shuga kapena chakudya chokhala ndi Malangizo apamwamba ogwiritsira ntchito: m chakudya. Pazifukwa izi, wodwalayo ayenera kukhala ndi 20 g shuga nthawi zonse. Mokulira kwambiri kwa hypoglycemia, jakisoni wokhazikika wa glucagon akuwonetsedwa (omwe angathe kuchitidwa ndi dokotala kapena antchito oyamwitsa). Pambuyo pakusintha kokwanira, wodwalayo ayenera kudya. Ngati hypoglycemia singathetsedwe mwachangu, ndiye kuti dokotala akuyenera kuyitanidwa mwachangu. Ndikofunikira kudziwitsa dokotala mwachangu za kukula kwa hypoglycemia kuti apange chisankho pakufunika kusintha kwa insulin.Kulephera kutsatira zakudya, kudumphira jakisoni wa insulin, kuchuluka kwa insulini chifukwa cha matenda opatsirana kapena matenda ena, komanso kuchepa kwa zochitika zolimbitsa thupi kungapangitse kuwonjezeka kwa ndende yamagazi (hyperglycemia), mwina ndi kuchuluka kwa matupi a ketone m'magazi (ketoacidosis). Ketoacidosis imatha kumatha maola ochepa kapena masiku. Pazizindikiro zoyambirira za metabolic acidosis (ludzu, kukodza pafupipafupi, kulephera kudya, kutopa, khungu lowuma, kupuma kwambiri komanso kuthamanga, chidwi cha acetone ndi glucose mkodzo), chithandizo chamankhwala chofunikira ndichofunikira.

Pakusintha dokotala (mwachitsanzo, nthawi yakuchipatala chifukwa cha ngozi, kudwala panthawi ya tchuthi), wodwalayo ayenera kudziwitsa dokotala kuti ali ndi matenda ashuga. Odwala ayenera kuchenjezedwa za machitidwe omwe zizindikiro zakuchenjeza za chitukuko cha hypoglycemia zingasinthe, osatchulika kapena kusapezeka kwathunthu, mwachitsanzo: ndi kusintha kwakukulu kwa kayendetsedwe ka glycemic, ndi kukula kwapang'onopang'ono kwa hypoglycemia, odwala okalamba, odwala omwe ali ndi vuto la neuronomic, mbiri yayitali ya matenda ashuga, odwala omwe amalandila chithandizo nthawi yomweyo ndimankhwala ena (onani gawo "Kuyanjana ndi mankhwala ena s). Zochitika zoterezi zimatha kuyambitsa kukula kwa hypoglycemia (komanso kutayika kwa magazi) wodwalayo asanadziwe kuti akupanga hypoglycemia. Ngati ma glycosylated hemoglobin apezeka bwino, muyenera kuganiziranso kuti zingatheke kukhala ndi gawo la hypoglycemia lomwe limachitika mobwerezabwereza.

Kuchepetsa chiopsezo cha hypoglycemia, wodwalayo ayenera kutsatira mosamala mlingo woyenera ndi zakudya zopatsa thanzi, kupereka jakisoni wa insulin ndikuchenjezedwa za zizindikiro za kukhala ndi hypoglycemia. Zinthu zomwe zimawonjezera kutsimikizira kwa chitukuko cha hypoglycemia zimafuna kuwunikira mosamala ndipo zingafune kusintha kwa mlingo. Zina mwazinthuzi ndi monga: kusintha kwa gawo la kayendetsedwe ka insulini, kuwonjezeka kwa chidwi cha insulin (mwachitsanzo, kuchotsa kwa nkhawa), zachilendo (kuchuluka kapena kuchita zinthu zolimbitsa thupi nthawi yayitali), matenda amtundu wamkati (kusanza, kutsegula m'mimba), chakudya chosakwanira, kudya chakudya, kumwa mowa, Matenda ena a uncocrensated endocrine (monga hypothyroidism ndi kusakwanira kwa anterior pituitary kapena adrenal cortex insuffence), kugwiritsa ntchito mankhwala ena (onani gawo "Kuyanjana ndi mankhwala ena"). Matenda apakati Pano okhala ndi matenda oyenda limodzi, mphamvu ya metabolic yofunika imafunikira. Nthawi zambiri, kuyesedwa kwa mkodzo kupezeka kwa matupi a ketone kumasonyezedwa, ndikusintha kwa insulin nthawi zambiri ndikofunikira. Kufunika kwa insulin nthawi zambiri kumachuluka. Odwala omwe ali ndi matenda amtundu wa 1 ayenera kupitiliratu kudya pang'ono, ngakhale atangomaliza kudya pang'onopang'ono kapena ngati akusanza, ndipo sayenera kusiya kumwa mankhwala a insulin.

Zotsatira zamtanda. Mwa kuchuluka kwakukulu kwa odwala omwe ali ndi hypersensitivity kupita ku insulin ya nyama, ndizovuta kusinthira kwa insulin yaumunthu chifukwa cha mtanda wa immunological wa insulini ya anthu ndi insulin yochokera nyama. Ndi chidwi chowonjezeka cha wodwalayo kuti apange insulin yakuchokera kwa nyama, komanso m-cresol, kulekerera kwa mankhwala a Insuman® Rapid GT kuyenera kuwunikiridwa kuchipatala pogwiritsa ntchito mayeso a intradermal. Ngati pakuyesedwa kwa insulin ya insulin ya munthu kumadziwika, zotsatira zake, monga Arthus, ndiye kuti chithandizo china chikuyenera kuyang'aniridwa ndi achipatala.

Kukopa pa kuyendetsa magalimoto kapena njila zina. Mphamvu ya wodwalayo yokhazikika komanso kuthamanga kwa zochitika zama psychomotor zitha kusokonezeka chifukwa cha hypoglycemia kapena hyperglycemia, komanso chifukwa chododometsa. Izi zimatha kukhala pachiwopsezo china chake munthawi yomwe maluso amafunikira (magalimoto oyendetsa kapena njira zina). Odwala ayenera kulangizidwa kuti asamale komanso kupewa hypoglycemia poyendetsa. Izi ndizofunikira kwambiri kwa odwala omwe achepetsa kapena kusazindikira zizindikiro zomwe zikuwonetsa kukula kwa hypoglycemia, kapena okhala ndi zochitika zapafupipafupi za hypoglycemia. Mwa odwalawa, funso loti akhoza kuwayendetsa ndi magalimoto kapena njira zina ayenera kusankha payekha.

Kuchita ndi mankhwala ena

Kugwiritsira ntchito mosiyanasiyana ndi othandizira pakamwa a hypoglycemic, angiotensin kutembenuza ma enzyme inhibitors, disopyramide, fibrate, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, propoxyphene, salicylates, amphetamine, anabolic steroids ndi abambo phenylphosphamphometrate, hemclophosphinometrate, hemclophosphometormin, hemocorhlometromu, hosphorphormines. , somatostatin ndi mawonekedwe ake, sulfonamides, tetracyclines, tritocqualin kapena trophosphamide Hypoglycemic zotsatira za insulin ndikuwonjezera kutengera kwa chitukuko cha hypoglycemia.

The ntchito kuphatikiza a corticotropin, corticosteroids, danazol, diazoxide, okodzetsa, glucagon, isoniazid, estrogens ndi progestogens (monga kupezeka mu kulera zosiyanasiyanazi kuphatikiza), opangidwa kuchokera phenothiazine, kukula timadzi, mankhwala sympathomimetic (mwachitsanzo, wa epinephrine, salbutamol, terbutaline), chithokomiro timadzi, barbiturates, nicotinic acid, phenolphthalein, phenytoin zotumphukira, doxazosin akhoza kufooketsa hypoglycemic zotsatira za insulin. Beta-blockers, clonidine, mchere wa lithiamu ukhoza kukhala wowonjezera kapena kufooketsa mphamvu ya hypoglycemic ya insulin.

Ethanol imatha kukhala yothandiza kapena kufooketsa mphamvu ya insulin. Kudya kwa Ethanol kumatha kuyambitsa hypoglycemia kapena kuchepetsa malangizo ochepa otsika: Magazi a glucose mpaka oopsa. Kulekerera kwa Ethanol mwa odwala omwe amalandira insulin kumachepetsedwa. Mitundu yovomerezeka ya zakumwa ziyenera kutsimikiziridwa ndi dokotala. Ndi makonzedwe munthawi yomweyo, kukulitsa kwa hypoglycemia ndikotheka, komwe nthawi zina kumatha kukhala hyperglycemia. Akaphatikizidwa ndi othandizira achifundo, monga beta-blockers, clonidine, guanethidine ndi reserpine, kufooka kapena kusapezeka kwathunthu kwa zizindikiro za Reflex (poyankha hypoglycemia) kutsegulira kwamanjenje kwamanjenje kumatha.

Contraindication

Hypoglycemia. Hypersensitivity reaction insulin kapena chilichonse chothandiza cha mankhwala. Ngati muli ndi amodzi mwa matenda kapena mikhalidwe imeneyi, onetsetsani kuti mukumana ndi dokotala musanagwiritse ntchito mankhwalawa. Chenjerani: Pakakhala kulephera kwa impso (mwina kuchepa kwa insulin chifukwa cha kuchepa kwa insulin metabolism). Odwala okalamba (kuchepa kwapang'onopang'ono kwa ntchito ya impso kungayambitse kuchepa kwa insulin kosowa). Odwala omwe ali ndi vuto la chiwindi (kufunika kwa insulin kumatha kuchepa chifukwa kuchepa kwa kuthekera kwa gluconeogeneis ndi kuchepa kwa insulin metabolism). Odwala omwe ali ndi stenosis yamphamvu kwambiri ya ubongo ndi matenda amitsempha yama cell (hypoglycemic episode atha kukhala ndi kufunikira kwapadera kwamankhwala, popeza pali chiopsezo cha mtima kapena matenda a mtima) a hypoglycemia. Odwala omwe ali ndi prinifosic prolifative retinopathy, makamaka omwe sanalandire chithandizo ndi Photocoagulation (laser therapy), popeza ali ndi chiopsezo chochepa kwamayurosis okhala ndi hypoglycemia wathunthu - khungu lathunthu. Odwala omwe ali ndi matenda ophatikizana (popeza matenda omwe amakumana nawo nthawi zambiri amawonjezera kufunika kwa insulin).

Ngati muli ndi amodzi mwa matenda kapena mikhalidwe imeneyi, onetsetsani kuti mukumana ndi dokotala musanagwiritse ntchito mankhwalawa. Mimba komanso mkaka wa m`mawere - Chithandizo ndi Insuman® Rapid GT panthawi yapakati iyenera kupitilizidwa. Insulin siyidutsa chotchinga. Kusunga moyenera kagayidwe kazakudya panthawi yonse yoyembekezera ndikovomerezeka kwa azimayi omwe ali ndi matenda ashuga asanabadwe, kapena amayi omwe apanga matenda a shuga. Kufunika kwa insulin panthawi yapakati kumatha kuchepa panthawi yayitali ya kubereka ndipo nthawi zambiri kumawonjezeka panthawi yachiwiri komanso yachitatu ya kutenga pakati. Pambuyo pobadwa, insulini ikucheperachepera (chiwopsezo cha hypoglycemia). Pa nthawi ya pakati komanso makamaka mukabereka mwana, kuwunika mosamala kuchuluka kwa shuga m'magazi kumafunika. Ngati muli ndi pakati kapena mukufuna kubereka, onetsetsani kuti mwadziwitsa dokotala. Panthawi yoyamwitsa, palibe zoletsa pazotsatira za insulin, komabe, mlingo wa insulin komanso kusintha kwa zakudya kungafunike.

Bongo

Zizindikiro: Kugwiritsa ntchito kwambiri insulini mwachitsanzo, kuphatikiza insulin yochulukirapo poyerekeza ndi chakudya kapena mphamvu zomwe zimagwiritsidwa ntchito, zimatha kuyambitsa hypoglycemia yayitali komanso nthawi yayitali. Chithandizo: Zochitika zofatsa za hypoglycemia (wodwalayo amadziwa) zitha kuyimitsidwa pakumeza chakudya. Kusintha kwa mlingo wa insulin, kudya, komanso zolimbitsa thupi kungafunike. Ziwonetsero zoopsa za hypoglycemia ndi chikomokere, kukomoka kapena kuchepa kwa mitsempha zimatha kuyimitsidwa ndi kutsekeka kapena kupindika kwa glucagon kapena kulowetsedwa kwa njira yokhazikika ya dextrose. Mu ana, kuchuluka kwa dextrose kutumikiridwa kumayikidwa molingana ndi kulemera kwa thupi la mwana. Pambuyo pakuwonjezera kuchuluka kwa shuga m'magazi, kuthandizira kudya zakudya zamagulu ndi kuwunika kungafunike, popeza pambuyo poti kuchipatala chithetsa zizindikiro za hypoglycemia, kukhazikikanso kwake ndikotheka. Mlandu wa hypoglycemia wowopsa kapena wotalika potsatira jakisoni wa glucagon kapena dextrose, tikulimbikitsidwa kuti kulowetsedwa kuchitike ndi yankho lozama la dextrose pofuna kupewa kukonzanso kwa hypoglycemia. Mu ana aang'ono, ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magazi, molingana ndi chitukuko chachikulu cha hyperglycemia. Pazinthu zina, ndikulimbikitsidwa kuti odwala azigonekedwa m'chipinda cha odwala osamala kwambiri kuti athe kuwonetsetsa momwe aliri.

Chithandizo: soluble insulin (maumboni amtundu wa anthu) 3.571 mg (100 IU),Othandizira: metacresol (m-cresol) - 2.7 mg, sodium dihydrogen phosphate dihydrate - 2.1 mg, glycerol 85% - 18.824 mg, sodium hydroxide (kusintha pH) - 0.576 mg, hydrochloric acid (kusintha pH) - 0,232 mg, madzi d / ndi - mpaka 1 ml

Zotsatira zoyipa Insuman Rapid GT

Kuchokera pamtima: pafupipafupi osadziwika - kuchepa kwa magazi.

Kuchokera kumbali ya kagayidwe ndi zakudya: nthawi zambiri - kutupa, kusadziwika pafupipafupi - kusungidwa kwa sodium. Zotsatira zomwezi zimatheka ndikusintha kwa kusakwanira kwa kagayidwe kachakudya chifukwa chogwiritsa ntchito kwambiri insulin.

Kuchokera kumbali ya gawo la masomphenyawo: kusunthika sikudziwika - kusokonezeka kowoneka kwakanthawi (chifukwa chakusintha kwakanthawi kwa ma mandala amaso ndi ma index awo othandizanso), kuwonongeka kwakanthawi machitidwe a matenda ashuga (chifukwa cha insulin yayikulu pakukonzanso kwakukulu pakulamulira kwamatenda a glycemic), makamaka osakhalitsa alandire chithandizo cha Photocoagulation (laser mankhwala).

Pa khungu ndi subcutaneous minofu: pafupipafupi sizikudziwika - kukula kwa lipodystrophy pamalo opangira jakisoni ndikuchepetsa kwa insulin. Kusintha komwe kumayambira jakisoni m'malo olimbikitsira kungathandize kuchepetsa kapena kusiya izi.

Zovuta ndi zovuta zina pamalo opangira jakisoni: pafupipafupi sizikudziwika - redness, ululu, kuyabwa, urticaria, kutupa kapena kutupa pakhungu. Zinthu zomwe zimatchulidwa kwambiri ndi insulini pamalo opangira jakisoni nthawi zambiri zimatha patatha masiku angapo kapena milungu ingapo.

Zizindikiro mwachitsanzo, insulin yochulukirapo, mwachitsanzo, kuyambitsa insulin yochulukirapo poyerekeza ndi chakudya kapena mphamvu, imatha kubweretsa hypoglycemia yayitali komanso nthawi yayitali.

Chithandizo: Zolemba zofatsa za hypoglycemia (wodwalayo amadziwa) zitha kuyimitsidwa ndikutenga chakudya mkati. Kusintha kwa mlingo wa insulin, kudya, komanso zolimbitsa thupi kungafunike. Ziwonetsero zoopsa za hypoglycemia ndi chikomokere, kukomoka kapena kuwonongeka kwa mitsempha zitha kuyimitsidwa ndi / m kapena s / c makonzedwe a glucagon kapena i / v ndi yankho la dextrose. Mu ana, kuchuluka kwa dextrose kutumikiridwa kumayikidwa molingana ndi kulemera kwa thupi la mwana. Pambuyo pakuwonjezera kuchuluka kwa shuga m'magazi, kudya zakudya zopatsa mphamvu komanso kuunika kungafunike, popeza Pambuyo pakuwonekera kachipatala pakutha kwa zizindikiro za hypoglycemia, kuyambiranso kwake ndikotheka. Milandu ya hypoglycemia yoopsa kapena yotalika potsatira jekeseni wa glucagon kapena dextrose, tikulimbikitsidwa kuti njira yotsika kwambiri ya dextrose imayikiridwa kuti tipewe kukonzanso kwa hypoglycemia. Mu ana aang'ono, ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magazi, molingana ndi chitukuko chachikulu cha hyperglycemia. Pazinthu zina, ndikulimbikitsidwa kuti wodwala azigonekedwa m'chipinda cha odwala osamala kwambiri kuti athe kuyang'anitsitsa momwe alili komanso kuwunika komwe akupitiliza kuchipatala.

Kugwiritsa ntchito mosiyanasiyana ndi mankhwala am'mlomo a hypoglycemic, ACE inhibitors, disopyramide, fibrate, fluoxetine, Mao inhibitors, pentoxifylline, propoxyphene, salicylates, amphetamine, anabolic steroids ndi mahomoni ogonana amuna, cybenzoline, phenophosphamine, phenophosphamine ndi phenophosphamine ake analogues, sulfonamides, tetracyclines, tritokvalin kapena trophosphamide amatha kupititsa patsogolo hypoglycemic zotsatira za insulin komanso draspolozhennost hypoglycemia.

The ntchito munthawi yomweyo corticotropin, corticosteroids, danazol, diazoxide, okodzetsa, glucagon, isoniazid, oestrogens ndi gestagens (mwachitsanzo, kupezeka PDA), phenothiazine ofanana nawo, kukula timadzi, mankhwala sympathomimetic (mwachitsanzo, wa epinephrine, salbutamol, terbutaline), mahomoni a chithokomiro, barbiturates, nicotinic acid, phenolphthalein, mankhwala a phenytoin, doxazosin imatha kufooketsa mphamvu ya insulin.

Beta-blockers, clonidine, mchere wa lithiamu ukhoza kukhala wowonjezera kapena kufooketsa mphamvu ya hypoglycemic ya insulin.

Ethanol imatha kupanga kapena kufooketsa mphamvu ya hypoglycemic ya insulin. Kudya kwa Ethanol kumatha kuyambitsa hypoglycemia kapena kuchepetsa shuga wambiri m'magazi kuti akhale owopsa.Kulekerera kwa Ethanol mwa odwala omwe amalandira insulin kumachepetsedwa. Dokotala ayenera kudziwa kuchuluka kovomerezeka kwa Mowa.

Pogwiritsa ntchito munthawi yomweyo ndi pentamidine, kukula kwa hypoglycemia ndikotheka, komwe nthawi zina kumatha kukhala hyperglycemia.

Pogwiritsa ntchito munthawi yomweyo ndi othandizira achifundo, monga beta-blockers, clonidine, guanethidine ndi reserpine, kufooka kapena kusapezeka kwathunthu kwa zizindikiro za Reflex (poyankha hypoglycemia) kuyambitsa kwamachitidwe amanjenje amanjenje ndikotheka.

Mankhwalawa amayenera kusungidwa pamalo amdima, osatheka ndi ana pa kutentha kwa 2 ° C mpaka 8 ° C. Moyo wa alumali: zaka ziwiri.

Mankhwala Opezeka

HOECHST MARION ROUSSEL Aventis Pharma Deutschland GmbH Aventis Pharma Deutschland GmbH / Sanofi-Aventis Vostok, Sanofi-Aventis Deutschland GmbH / Sanofi-Aventis Vosto Sanofi-Aventis Vostok, ZAO

Mikhalidwe yapadera

• 1 ml sungunuka wa insulin (maumboni amtundu wa anthu) 3.571 mg (100 IU) Othandizira: metacresol (m-cresol) - 2.7 mg, sodium dihydrogen phosphate dihydrate - 2.1 mg, glycerol 85% - 18.824 mg, sodium hydroxide (kusintha pH) - 0.576 mg, hydrochloric acid (kusintha pH) - 0,232 mg, madzi d / i - mpaka 1 ml. soluble insulin (genetic engineering) 3.571 mg (100 IU) Othandizira: metacresol (m-cresol), sodium dihydrogen phosphate dihydrate, glycerol 85%, sodium hydroxide (kusintha pH), hydrochloric acid (kusintha pH), madzi / ndi. soluble insulin (genetic engineering) 3.571 mg (100 IU) Othandizira: metacresol (m-cresol), sodium dihydrogen phosphate dihydrate, glycerol 85%, sodium hydroxide (kusintha pH), hydrochloric acid (kusintha pH), madzi / ndi.

Insuman Rapid GT Zowonetsa

• - monga gawo la zovuta za kukomoka pang'ono, mwachisawawa, popanda odwala, omwe ali ndi matenda a khunyu wazaka 16 ndi akulu. Wimpat ® mu mawonekedwe a infusions amalembedwa pokhapokha ngati mankhwala ndi osatheka kutenga mkati

Insuman Rapid GT zotsutsana

• - hypoglycemia, - hypersensitivity zimachitika ku insulin kapena chilichonse chothandiza cha mankhwala. Mochenjera, mankhwalawa ayenera kugwiritsidwa ntchito ngati mankhwalawa amalephera (kuchepa kwa insulin chifukwa cha kuchepa kwa insulin metabolism), mwa odwala okalamba (kuchepa kwapang'onopang'ono kwa ntchito yaimpso kungayambitse kuchepa kwakukulu kwa insulin), mwa odwala omwe ali ndi vuto la insulin (insulin ingafunike kuchepa chifukwa cha kuchepa kwa kuthekera kwa gluconeogeneis ndi kuchepa kwa insulin kagayidwe kake, mwa odwala omwe ali ndi vuto lalikulu la mitsempha ya m'mimba ndi mitsempha ya m'magazi (hypog zigawo zamatenda zimatha kukhala ndizofunikira zamankhwala, popeza pali chiopsezo cha mtima kapena matenda a mtima (hypoglycemia) mwa odwala omwe ali ndi proliferative retinopathy (makamaka omwe sanalandire chithandizo ndi Photocoagulation (laser therapy), popeza ali ndi chiopsezo chocheperapo kapenaurosis yokhala ndi hypoglycemia - khungu lathunthu ,

Insuman Rapid GT mavuto

• Hypoglycemia Hypoglycemia, njira yodziwika bwino ya mankhwala a insulin, imatha kupezeka ngati mlingo wa insulin woperekedwa umapitilira kufunikira kwake. Magawo obwerezabwereza a hypoglycemia angayambitse kukula kwa zizindikiro zamitsempha, kuphatikizapo chikomokere, kukokana. Kukhalitsa kwa nthawi yayitali kapena koopsa kwa hypoglycemia kumatha kukhala pachiwopsezo cha moyo. Odwala ambiri, zizindikiro ndi mawonekedwe a neuroglycopenia atha kukhala patsogolo ndi zizindikiro za Reflex (poyankha kukulitsa hypoglycemia) kutsegulira kwa mtima wamanjenje. Nthawi zambiri, ndi kuchepa kwambiri kapena kuchepa msanga kwa kuchuluka kwa shuga m'magazi, chodabwitsa cha kutseguka kwa mphamvu yamanjenje yomvera chisoni ndikuonetsa zizindikiro zake. Ndi kuchepa kwakukulu kwa kuchuluka kwa shuga m'magazi, kukulitsa kwa hypokalemia (zovuta kuchokera ku mtima) kapena kukula kwa edema yamatumbo. Otsatirawa ndi zochitika zoyipa zomwe zimawonedwa m'mayesero azachipatala omwe amadziwika ndi magulu a organic komanso kuchepa pafupipafupi:

Malo osungira

• khalani pamalo owuma
• Sungani kuzizira (t 2 - 5)
• osayandikira ana
• sungani pamalo amdima

Zambiri zoperekedwa ndi State Register of Medicines.

• Brinsulrapi MK, Brinsulrapi Ch, Insulin Actrapid, Levulin

Matenda a shuga ndi matenda oopsa omwe amakhudza anthu ochulukirapo tsiku lililonse. Zotsatira zake zimachitika chifukwa cha madzi ndi chakudya m'thupi la munthu.

Zotsatira zake, ntchito ya kapamba, yomwe imatulutsa insulin, imalephera. Hormoni iyi imakhudzidwa ndikupanga shuga mu glucose, ndipo popanda thupi thupi sangachite izi.

Chifukwa chake, shuga amadziunjikira m'magazi a wodwalayo, kenako amawatsitsa ndi mkodzo wambiri. Pamodzi ndi izi, kagayidwe kamadzi kamasokonezedwa, zomwe zimapangitsa kuchoka kwa madzi ambiri kudzera mu impso.

Mpaka pano, mankhwala amatha kupereka m'malo ambiri, omwe akupezeka mu njira yothetsera jakisoni. Chimodzi mwazida zoterezi ndi Insuman, yomwe tikambirana m'nkhaniyi.

Insuman Rapid GT - cholembera chomwe chili ndi yankho la kugwiritsa ntchito limodzi. Amatanthauzira ku gulu la mankhwala omwe ali ofanana ndi insulin yaumunthu. Za ndemanga za Insuman Rapid GT ndizambiri. Imatha kupanga kufooka kwa ambulensi amkati, omwe amapangidwa m'thupi ndi matenda ashuga.

Komanso, mankhwalawa amatha kutsitsa shuga m'magazi a anthu. Mankhwalawa amagwiritsidwa ntchito ngati jakisoni wa subcutaneous. Kuchitikaku kumachitika pakadutsa mphindi 30 kuchokera pakulowetsedwa, kumafika pakadutsa ola limodzi kapena awiri ndipo kumatha kupitirira, kutengera mlingo wa jakisoni, pafupifupi maola asanu kapena asanu ndi atatu.

SUSP. Insuman Bazal GT (syringe cholembera)

Insuman Bazal GT ilinso m'gulu la mankhwala omwe ali ofanana ndi insulin yaumunthu, amakhala ndi nthawi yayitali yochitapo kanthu ndipo amatha kupanga chifukwa chosowa insulin ya insulin yomwe imapangika mthupi la munthu.

About insulin Insuman Bazal GT ndemanga za odwala alinso abwino. Mankhwala amatha kutsitsa shuga. Mankhwalawa amathandizidwa mosavuta, zotsatira zake zimawonedwa kwa maola angapo, ndipo mphamvu yakeyo imatheka pambuyo pa maola anayi kapena asanu ndi limodzi. Kutalika kwa zochita zimatengera mlingo wa jakisoni, monga lamulo, zimasiyanasiyana maola 11 mpaka 20.

Zizindikiro zogwiritsidwa ntchito

• wodwala matenda ashuga
• acidosis
• shuga mellitus chifukwa cha zinthu zosiyanasiyana: opareshoni, matenda omwe amatsatiridwa ndi malungo, omwe ali ndi vuto la metabolic, atabereka mwana.
• predkomatoznoe mkhalidwe, womwe ndi chifukwa cha kusakhalitsa kwa chikumbumtima, gawo loyamba la chitukuko cha chikomokere.

• insulin yodalira matenda a shuga
• shuga yokhazikika yokhala ndi zosowa zochepa za insulin,
• kuchitira ena mwankhanza chithandizo.

Makanema okhudzana nawo

About nuances of use of insulin mankhwala Insuman Rapit ndi Basal mu kanema:

Insuman imagwiritsidwa ntchito pochiza odwala matenda a shuga mellitus. Ndizofanana ndi insulin yaumunthu. Amachepetsa shuga ndipo amapangitsa kuchepa kwa insulin. Amapezeka ngati yankho lomveka bwino la jakisoni. Mlingo, monga lamulo, umaperekedwa kwa wodwala aliyense payekhapayekha, wowerengeredwa pamaziko a mawonekedwe a matendawa.

Insulin "Insuman Rapid GT" ithandizanso kupereka msanga-kuchepetsa msanga zinthu zomwe zimachitika mphindi iliyonse. Kupatula apo, matenda ashuga ndi matenda oopsa omwe nthawi zambiri amachititsa kufa kapena kulumala. Kuti mupeze yankho la panthawi yake, othandizira osasinthika ndi jakisoni wa insulin yofulumira.

Kapangidwe ndi mfundo zowonetsera thupi

Mu 1 ml ya mankhwala muli:

• 100 IU ya insulin yosungunuka yofanana ndi anthu, omwe amafanana ndi 3,571 mg ya mahomoni amunthu.
• Zowonjezera:
  • glycerol 85%,
  • metacresol
  • sodium hydroxide
  • hydrochloric acid
  • sodium dihydrogen phosphate dihydrate,
  • madzi osungunuka.

Mankhwala a hypoglycemic "Insuman Rapid GT" amatanthauza insulin yochepa. Dzinalo Losayenerana Padziko Lonse (INN) -. Akatswiri opanga magesi a Gene adatha kusungunuka kwathunthu, ofanana ndi anthu, insulini. Imakhala ndi njira yochizira, yokhala ndi maola 9. Mphamvu yochepetsera shuga imadziwonekera pakatha mphindi 30, ikufika pachimake, pafupifupi, pambuyo pa maola awiri ndi atatu, kutengera kagayidwe ndi ntchito ya impso.

Mankhwala amakhudza thupi motere:

Mankhwala amathandizira kupanga glycogen.

• amathandiza kuchepetsa shuga
• imayambitsa kaphatikizidwe kazakudya,
• Imathandizira kukhutitsa maselo amwazi ndi potaziyamu
• amaletsa kusweka kwa lipid,
• imathandizira njira yosinthira shuga kuchokera ku chakudya chamafuta kukhala mafuta acids,
• amakwaniritsa maselo okhala ndi ma amino acid,
• kumawonjezera mapangidwe a glycogen,
• bwino kugwiritsa ntchito mankhwala omaliza a shuga kagayidwe,
• amachepetsa kuchuluka kwa njira za catabolic.

Syringe cholembera "Solostar" yogwiritsidwa ntchito kamodzi ingapangitse kuti magwiritsidwe ntchito a insulin akhale ochepa. Sichitenga nthawi yayitali komanso mosamala kukoka mankhwalawo mu syringe ya insulin: jakisoni yayamba kale jakisoni.

Zizindikiro ndi malangizo ogwiritsa ntchito

Insulin yovomerezeka imasonyezedwa kuti igwiritsidwa ntchito:

• odwala omwe amadalira insulin omwe ali ndi matenda a shuga,
• pochotsa matenda a hyperglycemic coma ndi kuchiza ketoacidosis,
• ngati cholowa pakuthandizira opaleshoni ya matenda ashuga.

Kuti mupeze mankhwala molondola, ndibwino kuti muwerenge malangizo musanawagwiritse ntchito.

Kuti muchepetse kuopsa kwa muyezo wolakwika wa mankhwalawa musanagwiritse ntchito, sikokwanira kungowerenga malangizo oti mugwiritse ntchito. Ndikofunikira kufunsa dokotala ndikuwerengera payekha payekha, zomwe zimatengera zinthu zambiri. Zambiri mwa izo ndi:

• kuchuluka kwa zochita zolimbitsa thupi za wodwala,
• kakhalidwe
• chakudya
• jenda, zaka komanso kulemera
• kumwa mankhwala ena
• kukhalapo kwa matenda osachiritsika.

Tiyenera kudziwa kuti ngati chimodzi mwazina zomwe zalembedwazo zasinthidwa, muyenera kufunsa dokotala kuti mupezenso kuchuluka kwa mankhwalawa. Ngakhale kusintha pang'ono kwa thupi kumatha kubweretsa zotsatirapo zosasangalatsa ngati simusintha mlingo wa insulin nthawi.

Malangizowa ali ndi malangizo onse kwa odwala onse:

• Mankhwalawa amaperekedwa pansi pa khungu musanadye kwa mphindi 15-20.
• Popewa kutulutsa khungu, ndikofunikira kupaka jakisoni m'malo osiyanasiyana nthawi zonse.
• Mtengo wa metabolism ndi pafupifupi 50% ya tsiku lililonse la insulin.
• Patsiku, thupi limafunikira insulini ndi 0,5-1.0 IU pa 1 kg yakulemera kwa thupi.
• Mankhwalawa amatha kuthandizidwa kudzera mu kuyang'aniridwa ndi madokotala kuchipatala.

Kodi mankhwalawa amagwira ntchito bwanji?

Insuman ndi insulin yopangidwa ndi anthu. Pa kukula kwa mafakitale, timadzi timene timapanga timabakiteriya. Poyerekeza ndi ma insulins omwe amagwiritsidwa ntchito kale, kupanga ma genetic kumakhala ndi zotsatira zokhazikika komanso kuyeretsa kwapamwamba.

M'mbuyomu, cholinga cha mankhwala a insulin chinali kulimbana ndi imfa. Ndi kuyamba kwa insulin ya anthu, vutoli lasintha. Tsopano tikulankhula zochepetsera chiopsezo cha zovuta komanso moyo wathunthu wa odwala. Zachidziwikire, kuti izi zitheke pama insulin analogs ndizosavuta, koma pa Insuman yolipira chindapusa cha shuga ndiyotheka. Kuti muchite izi, muyenera kuwerenga mosamala malangizo a mankhwalawo, momwe amagwirira ntchito, kuphunzira ndikusintha panthawi yake.

Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale

Matenda a shuga ndi omwe amayambitsa pafupifupi 80% yonse yamikwingwirima ndi kuduladula. Anthu 7 mwa anthu 10 amafa chifukwa cha mitsempha ya mtima kapena ubongo. Pafupifupi nthawi zonse, chifukwa chomaliza chomaliza ndi chimodzimodzi - shuga wamwazi.

Shuga akhoza ndipo amayenera kugwetsedwa, apo ayi. Koma izi sizichiritsa matendawa, koma zimangothandiza kulimbana ndi kufufuza, osati zomwe zimayambitsa matendawa.

Mankhwala okhawo omwe amalimbikitsidwa mwalamulo kwa odwala matenda ashuga komanso ogwiritsidwa ntchito ndi endocrinologists pantchito yawo ndi Ji Dao shuga patch.

Kugwiritsa ntchito bwino kwa mankhwalawa, kuwerengera malinga ndi njira yokhazikika (kuchuluka kwa odwala omwe achiwonjezere kuchuluka kwa odwala omwe ali pagulu la anthu 100 omwe adachitiridwa chithandizo):

• Matenda a shuga - 95%
• Kuthetsa kwa mitsempha thrombosis - 70%
• Kuthetsa kwa kugunda kwamtima kwamphamvu - 90%
• Kuthana ndi kuthamanga kwa magazi - 92%
• Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku - 97%

Opanga Ji Dao si bungwe lazamalonda ndipo amalipiridwa ndi boma. Chifukwa chake, tsopano wokhala aliyense ali ndi mwayi wopeza mankhwalawo kuchotsera 50%.

Kuphatikizika kwa mahomoni mu kapamba amoyo wathanzi ndikosakhazikika. Kutulutsa kwakukulu kwa insulin kumachitika poyankha glucose omwe amalowa m'mitsempha yamagazi kuchokera ku chakudya. Komabe, ngati munthu ali ndi njala kapena akugona, ndiye kuti pali insulin m'magazi, ngakhale itakhala yochepa kwambiri - pamlingo wotchedwa basal. Kupanga kwa timadzi timene timayamwa ndi matenda ashuga, mankhwala othandizira amayamba. Izi nthawi zambiri zimafuna mitundu iwiri ya insulin. Mulingo woyambira umatsata Insuman Bazal, imalowa m'magazi pang'onopang'ono, kwa nthawi yayitali komanso magawo ang'onoang'ono. Shuga mutatha kudya amapangidwira kuti muchepetse Insuman Rapid, yomwe imafikira zombo mwachangu kwambiri.

Makhalidwe oyerekeza a Insumans:

Zizindikiro		Wofulumira GT	Bazal GT
Kupanga		Insulin yaumunthu, zigawo zomwe zimachepetsa mayankho amawonongeka, zinthu zofunika kukonza acidity. Odwala matendawa ayenera kudziwa bwino mndandanda wonse wa omwe afotokozedwamo.	Kupangitsa kuti mahomoni azitha kuzizira pang'onopang'ono kuchokera ku minofu yaying'ono, protamine sulfate imawonjezedwanso kwa iye. Kuphatikiza kumeneku kumatchedwa insulin-isophan.
Gululi		Mwachidule	Yapakatikati (yowerengedwa motalika mpaka insulin analogues)
Mbiri yakuchita, maola	woyamba	0,5	1
	nsonga	1-4	3–4, nsonga yachepa.
	nthawi yonse	7-9	11-20, kuchuluka kwa mlingo, kumatenga nthawi yayitali.
Zizindikiro		Mankhwala a insulin a mtundu 1 komanso matenda a shuga a mtundu wa 2. Kuwongolera zovuta zamatenda a shuga, kuphatikiza osagwirizana ndi insulin. Kwakanthawi kochepa kochulukira kwamafuta. Pakanthawi povomerezeka kuti pakhale mapiritsi ochepetsa shuga.	Kungokhala ndi shuga wodalira insulin. Itha kugwiritsidwa ntchito popanda Rapid HT ngati zofunikira za insulin ndizochepa. Mwachitsanzo, kumayambiriro kwa mankhwala a insulin, lembani matenda ashuga a 2.
Njira zoyendetsera		Kunyumba - modzidzimuka, kuchipatala - kudzera m'mitsempha.	Pokhapokha ndi syringe cholembera kapena U100 insulini syringe.

Malamulo ogwiritsira ntchito

Kufunika kwa insulin ndi munthu aliyense payekha wodwala matenda ashuga. Monga lamulo, odwala omwe ali ndi matenda amtundu 2 komanso kunenepa kwambiri amafunikira mahomoni ambiri. Malinga ndi malangizo ogwiritsira ntchito, pafupifupi patsiku, odwala amapaka jekeseni 1 mpaka 1 kilogalamu ya mankhwala. Chiwerengerochi chikuphatikiza Insuman Bazal komanso Rapid. Insulin yochepa imakhala 40-60% ya zosowa zonse.

Insuman Bazal

Popeza Insuman Bazal GT imagwira ntchito osakwana tsiku limodzi, muyenera kuyikamo kawiri: m'mawa mutatha kuyeza shuga komanso musanagone. Mlingo wa makina aliwonse amawerengedwa mosiyana. Pazomwezi, pali mitundu yapadera yomwe imaganizira kukhudzidwa kwa mphamvu ya ma cell ndi glycemia. Mlingo woyenera uyenera kusunga kuchuluka kwa shuga panthawi yomwe wodwala matenda ashuga ali ndi njala.

Insuman Bazal ndi kuyimitsidwa, panthawi yosungirako imatulutsa: yankho lomveka limatsalira pamtunda, gawo loyera lili pansi. Pamaso pa jekeseni iliyonse, mankhwala osokoneza bongo muyenera kusakaniza bwino . Momwe kuyimitsidwa kumayambira, ndiye kuti mlingo womwe umafunawo udzalembetsedwa. Insuman Bazal ndiyosavuta kukonzekera kuposa makina ena apakati. Kupangitsa kusanganikirana, ma cartridge amakhala ndi mipira itatu, zomwe zimapangitsa kuti zikwaniritse bwino homogeneity wa kuyimitsidwa pamitundu 6 yokha ya cholembera.

Okonzeka kugwiritsa ntchito Insuman Bazal ali ndi utoto woyera. Chizindikiro cha kuwonongeka kwa mankhwalawa ndi mapepala, makristali, ndi mawonekedwe amtundu wina mu cartridge atasakanikirana.

Njira yolowetsera

Insuman imapangidwa ndi wopanga mu mawonekedwe a Mbale 5 ml, 3 ml cartridgeges ndi syringe pens. M'magulitsa ogulitsa ku Russia, ndizosavuta kugula mankhwala omwe amaikidwa mu zolembera za SoloStar syringe. Amakhala ndi 3 ml ya insulin ndipo sangathe kugwiritsidwa ntchito mankhwala atatha.

Momwe mungalowere Insuman:

1. Kuchepetsa ululu wa jakisoni ndikuchepetsa chiopsezo cha lipodystrophy, mankhwala omwe ali mu cholembera amayenera kukhala otentha kwambiri.
2. Asanagwiritse ntchito, katiriji amayang'aniridwa mosamala kuti awone zowonongeka. Kuti wodwala asasokoneze mitundu ya insulini, zolembera za syringe zimalembedwa ndi mphete za utoto zofanana ndi utoto wa zolembedwa paphukusili. Insuman Bazal GT - wobiriwira, Rapid GT - chikasu.
3. Insuman Bazal imakulungidwa pakati pa kanjedza kangapo kuti isakanikane.
4. Akutenga singano yatsopano pa jakisoni aliyense. Gwiritsani ntchito ntchito yanu kuwonongeka. Masingano ali konsekonse ali ngati zolembera za SoloStar: MicroFine, Insupen, NovoFine ndi ena. Kutalika kwa singano kumasankhidwa malinga ndi kukula kwa mafuta ochulukirapo.
5. Cholembera cha syringe chimakulolani kuti muzimudula kuyambira 1 mpaka 80 mayunitsi. Insumana, kulondola kwa dosing - 1 unit. Mwa ana ndi odwala omwe amakhala ndi zakudya zochepa zamagulu ochulukirapo, kufunikira kwa mahomoni kungakhale kochepa kwambiri, amafunikira kulondola kwapamwamba pakukhazikitsa. SoloStar siyabwino pamilandu yotere.
6. Insuman Rapid makamaka idalaswa m'mimba, Insuman Bazal - ntchafu kapena matako.
7. Pambuyo pakuyambitsa yankho, singano imasiyidwa m'thupi kwa masekondi 10 ena kuti mankhwalawo asayambe kutulutsa.
8. Mukatha kugwiritsa ntchito, singano imachotsedwa. Insulin imawopa kuwala kwa dzuwa, chifukwa chake muyenera kutseka cartridge mwachangu ndi kapu.

Zotsatira zoyipa

Ngati mankhwalawa amaperekedwa kuposa momwe amafunikira, zimachitika. Ndi omwe ali ndi vuto lotsatira kwambiri la insulin, mosasamala mtundu wa insulin yomwe imagwiritsidwa ntchito. Hypoglycemia imangokulira msanga, chifukwa chake ngakhale madontho pang'ono a shuga omwe amakhala pansi pazoyenera ayenera kuthetsedwa nthawi yomweyo.

Zotsatira zoyipa za Insuman mulinso:

Doctor of Medical Science, Mutu wa Institute of Diabetesology - Tatyana Yakovleva

Ndakhala ndikuphunzira matenda a shuga kwa zaka zambiri. Zimakhala zowopsa anthu ambiri akamwalira, ndipo makamaka amakhala olumala chifukwa cha matenda ashuga.

Ndithamangira kunena mbiri yabwino - Endocrinological Research Center ya Russian Academy of Medical Sayansi yakwanitsa kupanga mankhwala omwe amachiritsa odwala matenda ashuga mellitus. Pakadali pano, kugwiritsa ntchito bwino kwa mankhwalawa kuyandikira 98%.

Nkhani ina yabwino: Unduna wa Zaumoyo wateteza kukhazikitsidwa kwa pulogalamu yapadera yomwe imalipira mtengo wapamwamba wa mankhwalawa. Ku Russia, odwala matenda ashuga mpaka pa Epulo 23 (kuphatikiza) nditha kuipeza - Kwa ma ruble 147 okha!

1. Chiwopsezo kwa zigawo za yankho. Nthawi zambiri zimafotokozedwa poyabwa, redness, zotupa m'dera loyang'anira. Nthawi zambiri (malinga ndi malangizo, zosakwana 1%) anaphylactic zimachitika: bronchospasm, edema, dontho dontho, mantha.
2. Kusungidwa kwa sodium. Nthawi zambiri zimawonedwa kumayambiriro kwa chithandizo, pamene shuga kuchokera pamitundu yambiri imatsika kupita kwazonse. Hypernatremia imayendera limodzi ndi edema, kuthamanga kwa magazi, ludzu, kusokonekera.
3. Kapangidwe ka ma antibodies kupita ku insulin mthupi kumadziwika ndi chithandizo chambiri cha insulin. Poterepa, kuchuluka kwa Insuman kumafunikira. Ngati mlingo womwe mukufuna ndi waukulu kwambiri, wodwalayo amamuthandizira mtundu wina wa insulin kapena mankhwala a immunosuppress.
4. Kusintha kwakukulu pakubwezeretsanso shuga kungayambitse kuwonongeka kwakanthawi.

Nthawi zambiri, thupi limazolowera pang'onopang'ono insulin, ndipo matupi awo sagwirizana. Ngati zotsatira zoyipa zikuopseza moyo (anaphylactic shock) kapena sizimatha patatha masabata awiri, ndibwino kuti muthane ndi mankhwalawo. Insuman Bazal GT - kapena, Rapid GT -, kapena Humulin Regular. Mankhwalawa amasiyana muziperekazi. Mbiri yakuchitachita ndi yomweyo kwa iwo. Akadwala insulin yaumunthu, amasinthira ku insulin analogues.

Mtengo wa Insuman ndi wofanana ndi mtengo wamisonkho yake. Mankhwala omwe amapezeka m'matende a syringe amatenga ruble 1100. pa 15 ml (mayunitsi 1500, ma cholembera asanu). Isofan-insulin imaphatikizidwa pamndandanda wazamankhwala ofunika, momwe odwala matenda ashuga alili kuthekera kolandila kwaulere .