Kodi Meldonium ndi chiyani? Malangizo, mitengo ndi malingaliro

• jakisoni: madzi oyera, opanda utoto (5 ml aliyense m'milomo yopanda utoto yopanda utoto ndi mphete ya notch / kink, kapena popanda dontho ndi lingano / kink, ma ampoules 5 kapena 10 pamzere wamtundu / makatoni okhala ndi makatoni, pamatayala a bolodi 1) kapena matreti awiri a mizere / makatoni, kwa ma ampoule omwe ali ndi mphete ya kink kapena dontho ndi notch, mpeni wokwanira / zoperewera zimaphatikizidwa m'khitimu),
• makapisozi: gelatin yolimba, 250 mg - kukula No. 1, wokhala ndi thupi ndi kapu yoyera, 500 mg - kukula No. 00, wokhala ndi thupi loyera ndi kapu yachikasu, zofunikira - oyera a hygroscopic crystalline ufa wokhala ndi fungo linalake (10 iliyonse mu contour mapaketi amtundu, pamatoni a makatoni atatu kapena 6).

Paketi iliyonse ilinso ndi malangizo ogwiritsira ntchito Meldonium.

Muli 1 ml ya yankho:

• yogwira mankhwala: meldonium dihydrate - 100 mg,
• gawo lothandiza: madzi a jakisoni - mpaka 1 ml.

Kaphatikizidwe 1 kapisozi:

• yogwira mankhwala: meldonium dihydrate - 250 kapena 500 mg,
• othandizira: calcium stearate, colloidal silicon dioxide (aerosil), wowuma mbatata,
• 250 mg kapisozi kaphatikizidwe kazinthu: thupi ndi chivindikiro - gelatin ndi titanium dioxide,
• kapisozi kaphatikizidwe 500 mg: mlandu - gelatin ndi titanium dioxide, kapu - gelatin, mpweya wa titanium, utoto, dzuwa chikasu ndi chikasu cha quinoline.

Mankhwala

Gawo lomwe limagwiritsa ntchito mankhwalawa - meldonium dihydrate, ndi analogue ya kachitidwe ka gamma-butyrobetaine. Thupi limalepheretsa kuchuluka kwa ma cell a activated mitundu ya acid acids (omwe amachokera ku acylcarnitine ndi acylcoenzyme A), amachepetsa kuyendetsa mafuta ambiri ma cell mwa ma membrane am'mimba, amachepetsa kaphatikizidwe ka carnitine, ndipo amalepheretsa gamma-butyrobetaine hydroxynase. Chifukwa cha kuchepa kwa ndende ya carnitine, kaphatikizidwe kamene kamakhala ndi gamma-butyrobetaine, chinthu chomwe chili ndi vasodilating katundu, chimachitika.

Muzochitika za ischemia, Meldonium imabwezeretsa bwino momwe magwiritsidwe ntchito a mpweya ndikuperekera ma cell ndikugwiritsanso ntchito, komanso imalepheretsa kuphwanya kayendedwe ka angiotensin-akatembenuka enzyme (ATP). Kuphatikiza apo, mankhwalawa amayambitsa njira ya glycolysis, ikuchitika popanda kugwiritsa ntchito mpweya.

Chifukwa cha momwe amagwirira ntchito, Meldonium imakhala ndi zotsatirapo zake zamankhwala: kumawonjezera mphamvu yogwira ntchito, kumachepetsa kuwonetsa kwa thupi ndi kwamaganiza kwambiri, kuyambitsa minofu ndi chitetezo chamthupi, komanso kukhala ndi mtima wamtima.

Mu kuwonongeka kwa pachimake ischemic myocardial, mankhwalawa amalepheretsa mapangidwe a necrotic zone ndikuchepetsa nthawi ya kukonzanso. Mu milandu ischemic cerebrovascular ngozi (onse pachimake ndi aakulu), imalimbikitsa kugawa magazi m'malo mokomera ischemic malo ndipo imapangitsa magazi kutuluka kwambiri poyang'ana ischemia. Ndi kulephera kwa mtima, kumawonjezera kukhudzika kwa mtima, kumachepetsa pafupipafupi kuukira kwa angina, ndikukulitsa kulolerana kochita masewera olimbitsa thupi.

Kuchita bwino kwa Meldonium pankhani ya dystrophic ndi mtima pathological kwatsimikiziridwa.

Mankhwalawa ali ndi mphamvu yokhudza kupweteka kwamkatikati yamanjenje. Amachotsa magwiridwe antchito a dongosolo lodziyimira pawokha komanso amanjenje munthawi yochotsa odwala omwe ali ndi chidakwa.

Pharmacokinetics

Ndi mtsempha wamkati, meldonium imadziwika ndi bioavailability mwamtheradi - 100%. Kuzungulira kwakukulu (Cmax) mu plasma kumafikiridwa nthawi yomweyo jekeseni.

Mukamamwa pakamwa, kukhudzana kwa meldonium ndi 78%. Cmax mu plasma imawonedwa patatha maola 1-2 mutatenga kapisozi.

Mankhwala amakonzedwa kuti apange mitundu iwiri yayikulu ya metabolites yomwe imatsitsidwa ndi impso. Kuchotsa theka-moyo (T_1/2) itha kukhala kuyambira maola atatu mpaka 6

Zizindikiro zogwiritsidwa ntchito

Yankho ndi makapisozi:

• matenda a mtima (angina pectoris, myocardial infarction), mtima kulephera, mtima zam'maganizo kumbuyo kwa mawonekedwe a dishormonal - monga mbali ya zovuta mankhwala,
• pachimake komanso matenda osokonekera a cerebrovascular (cerebrovascular insufficiency, stroke) - monga gawo la zovuta mankhwala,
• kusiya achire matenda osokoneza bongo - kuwonjezera pa mankhwalawa enieni a uchidakwa wamphamvu,
• Kuchepetsa magwiridwe, kusokonezeka kwa malingaliro ndi thupi (kuphatikiza osewera).

Kuphatikiza apo, yankho - monga gawo la zovuta mankhwala:

• hemophthalmus ndi retinal hemorrhage osiyanasiyana etiologies,
• retinopathies a osiyanasiyana etiologies (kuphatikizapo matenda ashuga ndi hypertonic),
• thrombosis ya chapakati retine mtsempha ndi nthambi zake.

Zowonjezera za makapisozi: nthawi yothandizira (pofuna kuthamangitsa njira zokonzanso).

Contraindication

• kuchuluka kwazovuta zamkati (chifukwa cha kufooka kwaposachedwa ndi zotupa za intracranial),
• wazaka 18
• mimba
• kuyamwa
• Hypersensitivity pamagawo a mankhwala.

Meldonium iyenera kugwiritsidwa ntchito mosamala kwa odwala omwe ali ndi chiwindi chodwala komanso / kapena matenda a impso.

Yankho la jakisoni

Jakisoni wa Meldonium amathandizidwa ndi intramuscularly (i / m), intravenously (i / v) kapena parabulbarno.

Kukhazikitsidwa kwa mankhwalawa kumalimbikitsidwa m'mawa, chifukwa cha chitukuko cha chidwi.

Njira yoyendetsera, kuchuluka kwa Meldonium ndi nthawi yayitali yogwiritsira ntchito, dokotala amakhazikitsa payekha kutengera zomwe zikuwonetsa komanso kuopsa kwa vutolo.

Zovuta za matenda a mtima:

• myocardial infarction: iv mu ndege ya 500-1000 mg pa tsiku limodzi kapena awiri jakisoni,
• khansa ya angina pectoris yokhala ndi matenda a mtima, kuchepa kwa mtima ndi mtima chifukwa cha kusokonezeka kwa mahomoni: iv mu jet ya 500-1000 mg patsiku mu jekeseni limodzi kapena awiri kwa masiku 10 mpaka 14, ndiye kuti wodwalayo amapatsidwa mawonekedwe amkamwa. Njira yonse ya chithandizo ndi milungu 4-6.

Mankhwala ophatikizika a ngozi zamisala:

• pachimake gawo: iv 500 mg kamodzi patsiku kwa masiku 10 ndi kupititsa kwa wodwala kupita kukamwa kwamankhwala. Njira yonse ya chithandizo ndi masabata 4-6,
• aakulu mawonekedwe a matendawa: iv 500 mg kamodzi patsiku kwa masiku 10, kenako nkusamutsa wodwalayo pakamwa mankhwala. The ambiri maphunziro a 4-6 milungu, motsutsana ndi dokotala 2-3 pachaka maphunziro mobwerezabwereza maphunziro.

• matenda a ophthalmic: parabulbarno 50 mg pakatha masiku 10,
• uchidakwa wambiri: mu / mu kapena mu / mamilimita 500 kawiri pa tsiku kwa masiku 7-10,
• kuchuluka kwa zamaganizidwe ndi kuthupi: mu / mu kapena mu / m 500 mg 1 nthawi patsiku kwa masiku 10 mpaka 14. Ngati ndi kotheka, bwerezani maphunzirowa patatha milungu iwiri.

Mwanjira ya makapisozi, meldonium iyenera kumwa mkamwa musanadye.

Malangizo othandizira:

• kusokonezeka kwa magazi kupita ku ubongo: 500-1000 mg patsiku (makamaka mu theka loyamba la masanawa) kwa milungu 6,
• matenda a mtima osakhazikika, angina wokhazikika (monga gawo la mankhwala osokoneza bongo): 500-1000 mg patsiku limodzi kapena awiri Mlingo wambiri kwa masabata 4-6,
• Cardialgia chifukwa cha fatormonal myocardial dystrophy: 250 mg kawiri pa tsiku kwa masiku 12,
• kusiya mowa syndrome: 500 mg 4 pa tsiku kwa masiku 7-10,
• kuchepa kwa ntchito, kuchuluka kwa malingaliro ndi thupi, kuthamanga kwakanthawi kogwira ntchito: 250 mg 4 pa tsiku kwa masiku 10-14, ngati ndi kotheka, bwerezani chithandizo pambuyo masabata 2-3,
• kuchuluka kwa masewera othamanga: 500-1000 mg kawiri pa tsiku musanaphunzitsike masiku 14 mpaka 14 pakukonzekera, masiku 10 mpaka 14 pa mpikisano.

Mankhwala

Metabolism enhancer, gamma-butyrobetaine analogue. Imalepheretsa gamma-butyrobetaine hydroxynase, imalepheretsa kaphatikizidwe ka carnitine ndi kayendedwe ka mautali amafuta ambiri kudzera mumitsemvu yama cell, ndikulepheretsa kudzikundikira kwa mitundu yamafuta yama asidi mu maselo - zotumphukira za acylcarnitine ndi acylcoenzyme A.

Mikhalidwe ya ischemia, imabwezeretsa bwino momwe magwiritsidwe ntchito a mpweya ndikuperekera ma cell, imalepheretsa kuphwanyidwa kwa kayendedwe ka ATP, ndipo nthawi yomweyo imayambitsa glycolysis, yomwe imachitika popanda kugwiritsa ntchito mpweya.

Zotsatira zakuchepa kwa ndende ya carnitine, gamma-butyrobetaine yokhala ndi masodilating amapangidwe kwambiri. Limagwirira ntchito limazindikira kusiyanasiyana kwake zotsatira zake zamankhwala: kuwonjezeka kwa mphamvu, kuchepetsa mphamvu ya kupsinjika kwa malingaliro ndi thupi, kutseguka kwa minofu ndi kusakhazikika pakulimbitsa thupi, mtima.

Kugwiritsa ntchito bwino

Pankhani ya kuwonongeka kwa pachimake kwa ischemic ku myocardium, kumachepetsa mapangidwe a necrotic zone ndikufupikitsa nthawi yokonzanso. Ndi kulephera kwa mtima, kumawonjezera kuchepa kwa mtima, kumathandizira kulolerana, komanso kumachepetsa pafupipafupi matenda a angina.

Mu pachimake komanso matenda a ischemic matenda amitsempha yamagazi amatulutsa magazi mozungulira ischemia, amathandizira kugawa magazi mokomera dera la ischemic. Kugwiritsa kwa mtima ndi dystrophic matenda a fundus.

Imakhala ndi kukhudzika kwa chapakati mantha dongosolo, amachotsa magwiridwe antchito a mantha amthupi mwa odwala omwe ali ndi uchidakwa woperewera.

Kodi Meldonium ndi chiyani?

Zisonyezero zogwiritsidwa ntchito zimaphatikizapo zovuta mankhwala:

• kuchulukitsa kwakuthupi,
• maganizo achire mu zakumwa zoledzeretsa,
• Matenda a mtima wa Ischemic,
• Kuchepetsa magwiridwe
• ngozi zamisala,
• adalandir
• kukonzanso ntchito pambuyo.

Zomwe makonzedwe a parabulbar amathandizira kuchokera:

• retin vein thrombosis,
• retinopathies (matenda ashuga ndi hypertonic),
• retinal hemorrhage
• zovuta zamagazi mu retina.

Malangizo ogwiritsira ntchito

Meldonium imalimbikitsidwa kuti itengedwe m'mawa, chifukwa imatha kupanga zosangalatsa. Mlingo umayikidwa payekha kutengera zisonyezo ndi njira yoyendetsera.

Mukamwa, pakamwa limodzi ndi 0,25-1 g, kuchuluka kwa kayendetsedwe kake komanso nthawi yayitali ya chithandizo kumatengera zomwe akuwonetsa.

0,5 ml ya jekeseni yankho ndi kuchuluka kwa 500 mg / 5 ml kutumikiridwa parabulbarly kwa masiku 10.

Ndi mtsempha wa magazi makonzedwe, mlingo ndi 0,5-1 g 1 nthawi patsiku, nthawi ya mankhwala zimatengera zikuwonetsa.

Ochita masewera amapatsidwa chithandizo chobwezeretsa malingana ndi njira zapadera kuphatikiza ndi njira zina. Odziwika mwapadera ngati dope.

Momwe mungatengere ndi matenda?

1. Ngati kufalikira kwa matenda a ubongo, Meldonium imalimbikitsidwa nthawi yochulukirapo ya 0,5 g kamodzi patsiku kwa masiku 10, kenako osungidwa - 0,5 g tsiku lililonse kwa masiku 14 mpaka 14.
2. Mu mtundu wa ngozi ya ubongo. Njira yothetsera jakisoni imaperekedwa intramuscularly pa 0,5 g kamodzi patsiku kapena kutumikiridwa pakamwa pa 0,25 g (pafupipafupi makonzedwe amatengera kuuma kwa mkhalidwe wa wodwalayo).
3. Kuchotsa matenda kumafuna njira yochizira ndi Meldonium kwa masiku 7-10. Kenako wodwalayo akuwonetsedwa kumwa kwa mankhwalawa kwa nthawi yayitali, 0,5 g mkati kapena nthawi ziwiri.
4. Ndi khola la angina pectoris, masiku oyamba atatu a 3 ndi 3 ali 3,5 ga katatu. Kenako amatengedwa pakamwa kawiri pa sabata pa tsiku la 0,25 ga katatu. Kutalika kwa mankhwalawa ndikuchokera ku milungu 4 mpaka 6.
5. Ndi cardialgia, kuphatikiza ndi dishormonal myocardial dystrophy, mankhwalawa amathandizidwa kudzera m'njira ya jet kamodzi patsiku, 0,5-1 g kapena IM mpaka 2 pa tsiku, 0,5 g patatha masiku 10 mpaka 14, mawonekedwe a kapisozi adayikidwa 0.25 mg m'mawa ndi madzulo, chithandizo chimapitilizidwa kwa masiku ena 12.
6. Ndi mawonekedwe osasunthika a angina pectoris ndi infrction ya myocardial, Meldonium imagwiritsidwa ntchito kudzera m'mitsempha ya ndege ya 0,5 g kapena 1 g kamodzi patsiku. Pambuyo pake, amalembedwa pakamwa: masiku 3-4 - 0,25 ga 2 kawiri, ndiye masiku 2 pa sabata 0,25 g katatu pa tsiku.
7. Pankhani ya mtima matenda a fundus, retinal dystrophy, Meldonium ndi zotchulidwa retrobulbarly ndi subconjunctively pa 0,05 g pakapita masiku 10.
8. Matenda osalephera a mtima, mankhwalawa amaperekedwa mu jet tsiku lililonse pamankhwala a 0.5-1 g kapena m'malo ndi jakisoni wa 0.5 g mpaka 2 kawiri pa tsiku. Pambuyo masiku 10-14 chithandizo, wodwalayo amasamutsidwa 0,5 g makapu, omwe amatenga nthawi 1 m'mawa. Njira ya mankhwalawa imachokera ku milungu 4 mpaka 6.

Ana pa mimba ndi mkaka wa m`mawere

Meldonium sinafotokozeredwe kwa amayi apakati, chifukwa sizinali zotheka kutsimikizira chitetezo chake kwa mayi ndi mwana. Ngati mukufunikira kupereka mankhwala kwa mayi woyamwitsa, ndiye panthawi ya chithandizo, kuyamwitsa kumayimitsidwa: sizikudziwika ngati chinthucho chimalowa mkaka.

Mwa ana ndi achinyamata ochepera zaka 18, kugwiritsa ntchito bwino kwa meldonium sikunakhazikitsidwe. Meldonium mu mawonekedwe a makapisozi amatsutsana kuti agwiritsidwe ntchito mwa ana ndi achinyamata osakwana zaka 18, mu mawonekedwe a madzi ana osakwana zaka 12.

Malangizo apadera

Gwiritsani ntchito mosamala matenda a chiwindi ndi / kapena impso, makamaka kwa nthawi yayitali.

Pazaka zambiri pazachidziwitso cha infarction yokomera ndi kusakhazikika kwa angina m'madipatimenti a mtima imawonetsa kuti meldonium sakhala njira yoyamba yothandizira odwala pachimake coronary syndrome.

Makhalidwe wamba

Meldonium ndi chinthu chomwe ndi gawo la mankhwala ambiri. Koma ena opanga mankhwala opanga mankhwala amadzimasulira ngati mankhwala odziyimira pawokha, popeza ali ndi mphamvu ya metabolic ndi antihypoxic, zimakhudza bwino mitsempha ndi mtima.

Meldonium ndi mankhwala a gulu la metabolic othandizira. Dzinalo losagwirizana padziko lonse lapansi limafanana ndi chinthu chomwe chimagwira - Meldonium.

Zokhudza thupi ndi pharmacokinetics

Kugwiritsa ntchito kwa Meldonium mu mtima ndi mankhwala amafotokozedwa ndi zomwe ali nazo. Kamodzi m'thupi, imagwira mbali zingapo nthawi imodzi:

• normalization kagayidwe,
• Imachepetsa minofu necrosis, imalimbikitsa kuchira msanga ku vuto la mtima,
• Imalimbikitsa kukhudzika kwa mtima, imawonjezera kukana kwake kuchita zolimbitsa thupi,
• amachepetsa kuchulukana kwa angina,
• imathandizira magazi mu ubongo,
• chimalimbikitsa chitetezo chokwanira
• imathandizanso kuonetsa matenda amisala, nkhawa kwambiri,
• Amasintha magwiridwe, kupirira,
• amathetsa zizindikiro zochotseka zomwe zidatulukira poyambira kumwa kwa nthawi yayitali.

Mankhwala ali ndi zabwino zambiri. Koma sikulimbikitsidwa kuti mugwiritse ntchito popanda kufunsa dokotala. Sankhani bwino kuchuluka kwa mankhwala omwe akatswiri okhawo amatha kudziwa.

Kutulutsa fomu, mtengo

Pamsika wamankhwala, pali mitundu iwiri:

• Makapisozi - okhala ndi mawonekedwe a cylindrical okhala ndi malekezero a hemispatical a mtundu woyera. Amayikidwa m'maselo a 10 zidutswa. Chiwerengero cha matuza mumpukutuwo ndi 3 kapena 6.
• Njira yothetsera - imagwiritsidwa ntchito kudzera m'mitsempha, intramuscularly kapena parabulbarno. Kuikidwa mu 5 ml ampoules. Kuchuluka kwa zomwe zili mu phukusi ndi 10.

Mtengo wa Meldonium umatengera mtundu wa kumasulidwa kwake, dera logulitsa ndi wopanga (Gome 1).

Gome 1 - Mtengo m'mafakitala a zigawo zosiyanasiyana

Mtengo wa mapiritsi a Meldonium ndi ofanana ndipo umachokera ku 156 mpaka 205 rubles. Kuti mugule mankhwalawa, muyenera kupatsa dokotala mankhwala.

Zigawo

Makapisozi ali ndi 250 kapena 500 mg yogwira ntchito ndi zinthu zake:

• colloidal silicon dioxide,
• wowuma mbatata
• magnesium wakuba.

Limagwirira zake ntchito mankhwala

Chigoba cha kapisozi chimapangidwa kuchokera:

• glycerin
• madzi
• sodium lauryl sulfate,
• titanium dioxide
• gelatin.

The ampoule ndi Meldonium yankho lili ndi 0,5 g yogwira ntchito. Chowonjezera china cha mankhwala a mawonekedwe awa ndi madzi okha.

Zizindikiro ndi contraindication

Kukula kwa Meldonium ndi kotakata. Amalembera matenda a kupuma dongosolo ndi maso, mtima pathologies ndi mtima. Mankhwala atha kuperekedwa:

• vuto la mtima
• angina pectoris,
• Cardialgic syndrome yoyambitsidwa ndi kutsika kwa thupi kwa minofu ya mtima,
• ochepa ogwira ntchito
• kusokonezeka kwakukulu kwa kayendedwe ka magazi mu retina,
• kutopa kwa thupi,
• kulephera kwa mtima,
• magazi m'matumbo a retina ochokera kosiyanasiyana,
• ischemic stroke
• Matenda am'mbuyo, omwe ndi zovuta za matenda a shuga, matenda oopsa,
• discirculatory encephalopathy,
• chifuwa
• kupezeka kwa magazi m'zigawo zikuluzikulu za retina,
• kusiya mowa,
• mphumu ya bronchial.

Meldonium imagwiritsidwanso ntchito pambuyo pakuchita opaleshoni - kuti ifulumizitse njira yobwezeretsanso komanso kukonza minofu yambiri.

Monga mankhwala onse, mankhwalawa ali ndi contraindication. Zomwe zimapatula mwayi wogwiritsidwa ntchito ndizophatikiza:

• kuthamangitsidwa pamatumbo,
• tsankho pamagawo a mankhwala,
• zaka za ana (asanafike zaka 18, kumwa mankhwala osavomerezeka).

Odwala ndi matenda a chiwindi ndi impso ndi mankhwala mankhwala mosamala. Kugwiritsa ntchito kwa Meldonium pamaso pa contraindication koletsedwa: izi zimawopseza kukhala ndi thanzi labwino, kukulira kwa zovuta zotsutsana ndi maziko a matenda oyambitsidwa.

Momwe mungawerengere kuchuluka kwa mapiritsi ndi yankho?

Kuchuluka kwa mankhwalawa amatengera wodwala ndi mtundu wa matenda ake.

Mlingo wovomerezeka wa Meldonium mu mowa wochotsa mowa ndi 500 mg. Amatengedwa pakamwa kapena kubayidwa m'mitsempha. Poyambirira, mankhwalawa amagwiritsidwa ntchito mpaka 4 pa tsiku, chachiwiri - osaposa 2 times. Kutalika kwa mankhwalawa ndi masabata 1.5.

Ndi kutopa kwakuthupi, komanso pambuyo pakuchita opaleshoni, ndikofunikira kumwa Meldonium kanayi pa tsiku. Mlingo umodzi ndi 0,25 g. Koma mutha kugwiritsa ntchito yankho. Amabayidwa m'mitsempha kapena minofu ya gluteus yambiri 0,5-1 g.

Pafupipafupi makonzedwe a mankhwala kudzera m`mitsempha kamodzi pa tsiku. Ndikokwanira kuphatikiza mankhwalawa katatu patsiku. Dongosolo lotere la mankhwala limatsatiridwa kwa masabata 1.5-2. Ngati akuwonetsa, chithandizo chimabwerezedwa pambuyo pa masiku 14 mpaka 14.

Odwala omwe ali ndi vuto lalikulu la magazi m'magazi amagwiritsa ntchito mankhwalawa malinga ndi chiwembuchi: masiku 10, yankho la mankhwalawa mu kuchuluka kwa 500 mg patsiku limalowetsedwa m'mitsempha, pambuyo pake amatenga kapisozi kwa masabata ena a 2-3. Mlingo komanso pafupipafupi kumwa mankhwalawa sizisintha.

Poyerekeza ndi momwe mankhwalawo amathandizira ndi Meldonium, zotsatira zosangalatsa zingachitike. Chifukwa chake, ndibwino kugwiritsa ntchito m'mawa. Makapisozi amaledzera musanadye, ndi madzi ambiri.

Matenda a mtima

Meldonium sakuphatikizidwa m'gulu la mankhwala osankhidwa pochiza matenda a mtima, mtima wamitsempha yama cell: ngati mankhwala odziyimira pawokha satha ntchito. Kugwiritsidwa ntchito kwake kumayesedwa ngati gawo limodzi la zovuta zochizira matenda a angina pectoris, infarction ya myocardial, cardialgia ndi minofu ya mtima kulephera.

Odwala omwe ali ndi khola la angina pectoris amatenga 250 mg a meldonium katatu patsiku kwa masiku 3-4. M'tsogolomu, mankhwalawa amagwiritsidwa ntchito malinga ndi chiwembu chomwecho, koma kawiri pa sabata. Njira ya chithandizo ndi miyezi 1-1.5.

Zochizira za cardialgia, zomwe zimawonekera chifukwa cha kudwala kwa mtima, ndikulimbikitsidwa kuyambitsa Meldonium mu mitsempha kapena minofu pa mlingo wa 500 mg. Poyambirira, thunthu limagwiritsidwa ntchito kamodzi patsiku, lachiwiri - kawiri pa tsiku. Mankhwalawa amatenga masabata 1.5-2. Pambuyo pa nthawi imeneyi, imwani mapiritsi. Mlingo wawo watsiku ndi tsiku ndi 500 mg (mapiritsi awiri okhala ndi 250 mg yogwira ntchito). Iagawidwa pawiri. Chithandizo chimapitilizidwa kwa masiku ena 12.

Ndi kulowetsedwa kwa myocardial, angina osakhazikika m'masiku oyamba a chithandizo, Meldonium imagwiritsidwa ntchito kudzera m'mitsempha: 0.5-1 g yankho limayendetsedwa. Masiku atatu otsatirawa, tengani makapisozi: 250 mg kawiri pa tsiku. Pambuyo pa nthawi imeneyi, pafupipafupi kumwa mankhwalawa amachulukitsa katatu, koma umagwiritsidwa ntchito pakapita masiku atatu aliwonse.

Omwe adapezeka ndi vuto la mtima akudwala amadziwika kuti ali ndi njira ya Meldonium yothetsera masiku 10-14. Mlingo komanso pafupipafupi kugwiritsa ntchito kwake ndi 0.5-1 g ndi 1 kapena 2 kawiri pa tsiku, motero. Pambuyo pa masabata awiri, makapisozi amatchulidwa muyezo womwewo. Kutalika konse kwa chithandizo ndi miyezi 1-1.5.

Meldonium imathandizira kuperekera kwa myocardium, minofu ya m'magazi ndi magazi ndi mpweya, imathandizira njira zama metabolic, ndikuwonjezera kupirira. Chifukwa chake, sagwiritsidwira ntchito mu mankhwala, komanso zamasewera.

Tiyenera kumvetsetsa kuti Meldonium siyikukhudza mwachindunji kuwonjezeka kwa minofu kuchuluka kwa osewera, imayimitsa zizindikiro zowonjezera, imalimbikitsa mphamvu ya thupi, yomwe imalola kukulitsa maphunziro komanso nthawi yayitali.

Limagwirira a zochita za mankhwalawa amatengera kuyimitsa zotsatira za carnitine, zomwe zimakupatsani mwayi wosinthira thupi kuyamwa ndikuyamba kugwiritsa ntchito shuga mphamvu.

Mlingo woyenera wa mankhwalawa panthawi yochita masewera olimbitsa thupi ndi 0,5-1 gm.Mapiritsi amayenera kuledzera kawiri pa tsiku kwa theka la ola musanaphunzire. Kutalika kwa mankhwalawa ndikuchokera ku milungu iwiri mpaka itatu.

Kwa nthawi yayitali, Meldonium adatengedwa ndi osewera padziko lonse lapansi kuti awonjezere kulolerana. Koma lero ndizoletsedwa kuzigwiritsa ntchito pamasewera akatswiri. Kuyambira mu 2016, adadziwika kuti ndi doping. Chifukwa cha kugwiritsidwa ntchito kwake kumawopseza kusayenerera kwa zaka 4.

Kuchepetsa thupi

Masiku ano, munthu amatha kupeza malingaliro oti Meldonium amathandizira kuchepetsa kunenepa. Kodi zili choncho? Imagwira nawo mu mawonekedwe a cellular, motero mphamvu yonse ya thupi, chifukwa cha antioxidant katundu, detoxifying.

Cholesterol chabwino komanso choyipa

Njira izi zitha kuchepetsa kwambiri cholesterol yoyipa mthupi, komabe ndikofunikira kumvetsetsa kuti monga njira yodziyimira yothana ndi mapaundi owonjezera, sikuthandiza. Kuti mukwaniritse zomwe mukufuna, ndikofunikira kuphatikiza phwando lake ndi masewera olimbitsa thupi: kulimbitsa thupi, kuthamanga, kuthamanga, kuthamanga. Izi zithandiza kukonza kagayidwe kazinthu komanso momwe thupi limayankhira kupsinjika, ndipo zimabweretsa kuwonda.

Ndikofunikira kutenga Meldonium m'mapiritsi kuti muchepetse thupi musanayambe kuchita masewera olimbitsa thupi a 0,5-1. Muyenera kumwa mankhwalawa m'mawa: kumwa usiku kumatha kubweretsa kusowa tulo.

Meldonium, malangizo ogwiritsira ntchito (Njira ndi Mlingo)

Makapisozi Meldonium-MIK kutengedwa pakamwa komanso pokhudzana ndi kuthekera kosangalatsa, tikulimbikitsidwa kuti mudzatenge m'mawa. Mlingo komanso kuchuluka kwa makonzedwe amasankhidwa payekha.

Ndi matenda amtima - 500 mg-1000 mg patsiku. Chithandizo chimatenga mpaka milungu isanu ndi umodzi.

Mu ngozi ya cerebrovascular - 500 mg kamodzi patsiku, patapita masabata 4-6.

At achire syndrome - 500 mg 4 pa tsiku.

Ndi kuchuluka kwa thupi - 250 mg kanayi pa tsiku, masiku 14.

Bongo

Mankhwalawa ali ndi poizoni pang'ono ndipo milandu ya bongo yambiri sikuchitika kapena ndizosowa kwambiri. Kukula kumatheka hypotension, tachycardia, mutu, chizungulire ndi kufooka wamba. Mankhwala othandizira amachitika.

Kuchita

Imawonjezera ntchito ya antihypertensive, antianginal mankhwala, mtima glycosides.

Mwina kuphatikiza ndi antianginal mankhwala, anticoagulants, antiarrhythmic mankhwala ndi okodzetsa.

Ndi munthawi yomweyo kugwiritsa ntchito Nitroglycerin, alpha blockers, Nifedipinezotumphukira vasodilators ayenera tachycardia ndi ochepa hypotension.

Osagwiritsa ntchito nthawi yomweyo ndi mankhwala ena okhala meldonium.

Ndemanga za Meldonia

Kukhazikitsidwa kwa mankhwala mankhwalawa matenda a mtima kumachepetsa ndi 55,6% kuchuluka kwa khunyu angina pectoris ndi zofunika tsiku lililonse nitroglycerin ndi 55.1%. Amasintha bwino mgwirizano myocardium osagwirizana ndi kugunda kwa mtima, amachepetsa kusinthasintha HERE. Mankhwalawa ali ndi poizoni wambiri ndipo samayambitsa zovuta zoyipa.

Poona ndemanga za odwala, mankhwalawa adathandizidwa Matenda a mtima wa Ischemic kuphatikiza ndi antianginal ndi antihypertensive mankhwala. Ndikofunikira kuti mankhwalawa adapangidwira odwala omwe ali ndi zaka zachikulire ndipo amalekerera bwino.

• «... Ndawonjezera mapiritsi a Meldonium a angina pectoris, pamapiritsi ena. Zowonekera pambuyo pa masabata atatu»,
• «... Ndinatenga kangapo patsiku 2 pambuyo pa sitiroko yama cell yaying'ono. Anamweka mwezi ndi theka - kuyankhula bwino, kulimba»,
• «... Ndimatenga maphunziro katatu pachaka. Nditha kuzitchula kuti ndizofunikira kwa aliyense. Ndili ndi angina pectoris komanso kuthamanga kwa magazi»,
• «... Mwanayo ali ndi chaka chimodzi, watopa kwambiri. Pondipangira katswiri wamitsempha, ndimatenga Meldonium kawiri pa tsiku. Ndimamwa sabata limodzi lokha ndipo ndimamva bwino»,
• «... Ndidalimbikitsidwa ndi katswiri wazokhudza mitsempha (matenda a "kutopa"). Mabakiteriya opukutidwa. Mankhwala abwino, amabwerera mphamvu mofulumira»,
• «... Ndazindikira kuti kutenga Meldonium kumawonjezera chidwi, ngakhale kuchira pang'ono»,
• «... Patatha masiku 7 nditamwa mankhwalawa, mutu wanga unayamba chizungulire».

Analogs a mankhwala Meldonium

Kapangidwe kamene kamayimira fanizo:

1. Vasomag.
2. Meldonium dihydrate.
3. Idrinol
4. Meldonium Organics (Binergia, Eskom).
5. Angiocardyl.
6. 3- (2,2,2-Trimethylhydrazinium) propionate dihydrate.
7. Cardionate
8. Midolat.
9. Medatern.
10. Melfort.
11. Mildronate

Zochizira kuchuluka kwa thupi ndi malingaliro, kuchira kwamthupi, analogi ndi mankhwala:

1. Lamivit.
2. Kutulutsa kwa Eleutherococcus.
3. Gypsy.
4. Yantavit.
5. Falkamine.
6. Ascovite.
7. Galavit.
8. Centrum.
9. Cardionate
10. Achimor.
11. Hepargin.
12. Triovit.
13. Idrinol
14. Eltacin.
15. Corilip.
16. Ribonosin
17. Vazoton (L-arginine).
18. Vasomag.
19. Selmevit.
20. Pikovit forte.
21. Berocca Kuphatikiza.
22. Pantogam.
23. Heptolexin.
24. Mildronate
25. Vitatress.
26. Ubiquinone compositum.
27. Valeocor Q10.
28. Pikovit.
29. Coudewita.
30. Carnitine.
31. Dibikor.
32. Trekrezan.
33. Vitaspectrum.
34. Elkar.
35. Riboxin
36. Vitamax
37. Pantocalcin.
38. Ma antioxidants okhala ndi ayodini.
39. Cytoflavin.
40. Cropanol.
41. Neoton.
42. Nagipol.
43. Mexicoidol.
44. Jeriton.
45. Oligovit.
46. Duovit.
47. Encephabol.
48. Kudesan.
49. Metaprot.
50. Zowonjezera ndi chitsulo.
51. Asvitol.
52. Inosine.
53. Vitrum Plus.
54. Chuma cha Leriton.
55. Drops Beresh Plus.
56. Coenzyme compositum.

Pa nthawi yoyembekezera

Kutha kwa Meldonium kulowa mkati mwa placenta ndi mkaka wa m'mawere, momwe zimakhudzira mwana wosabadwayo komanso kukula kwa mwana sizikumveka bwino. Chifukwa chake, malinga ndi malangizo, kugwiritsa ntchito kwake sikulimbikitsidwa kwa amayi apakati komanso amayi oyamwitsa.

Ngakhale zili zochepa zomwe zafotokozedwa pamwambapa, lero Meldonium nthawi zina amagwiritsidwa ntchito pochiritsa amayi apakati. Zizindikiro zitha kukhala:

Fetoplacental kuchepa. Izi matenda amayamba chifukwa kuphwanya magazi a m'mimba, chifukwa chake mwana wosabadwayo. Mkhalidwe wowopsa ungayambitse imfa ya mwana. Izi ndizovuta kuthana, chifukwa chake, ngati njira yodzidzimutsa, Meldonium nthawi zina imalembedwa, yomwe imachepetsa kufunikira kwa okosijeni m'maselo a mayi ndi mwana wosabadwayo, kupewa kukula kwa hypoxia, komanso kupewa kuledzera.

Kulephera pantchito, makamaka kwakanthawi kochepa, chifukwa cha momwe thupi la mayi limakhudzira kwambiri, ndipo mwana amakumana ndi vuto la hypoxia. Izi zimatha kubweretsa mavuto akulu, ngakhale kufa.

Meldonium imakupatsani mwayi wolimbitsa ntchito yamanjenje ya mkazi yemwe ali ndi pakati ndi mwana wosabadwa, komanso kusintha njira yobereka. M'pofunika kunena kuti mankhwalawa samapereka mpweya wowonjezera m'maselo, koma amachepetsa kufunika kwake.

Ndemanga za madotolo za meldonium

Mankhwala "Meldonium", omwe molekyulu yake imakhudzidwa ndi kuphatikiza mamolekyu amagetsi (Adenositol triphosphate), kuphatikiza mavitamini a B, amaphatikiza bwino mankhwala osapatsirana a antiidal omwe amathandizira dorsopathies ochokera kumayendedwe osiyanasiyana.

Zokhudza momwe odwala amakhudzidwira pomvera kuti adayikidwa "doping" (1 nthawi).

Zimagwira ngati mukudziwa kuti ndi chifukwa chani muyenera kusankha. Popeza kuti mankhwalawa ndi osadetseka kwambiri ndipo akhoza kukhala ndi vuto la placebo sayeneranso kuiwalika, chifukwa tikamapereka mankhwala, nthawi zambiri timapereka mankhwala othandizira.

Sitha kugwiritsidwa ntchito mu monotherapy, odwala ambiri amasangalala, koma ena samamva momwe zimakhalira.

Mankhwala, monga, masiku ano ambiri, ali ndi chidziwitso chabwino cha kulolera, panalibe zoyipa zilizonse, amalekerera mosavuta odwala ngakhale molumikizana ndi chithandizo chachikulu cha concomitant, komabe, ngakhale atakhala umboni, simutha mwanjira ina kuti musamve ndi piritsi yomwe imachiritsa makamaka, ali pafupi ndi zowonjezera za bio, mavitamini.

Mankhwala otsika mtengo, oyeserera nthawi, komanso othandiza

Kuti mupeze kufunika komwe mukufunikira, muyenera kumwa monga adokotala adanenera, muyezo wabwino komanso nthawi yoyenera. Ngati vutoli silikukhutiritsa - nthawi zambiri si vuto la mankhwalawa, koma kutanthauzira kolakwika kwa matendawa kapena kuperewera kwa mankhwala.

Meldonium ndi wabwino kwambiri kukonzekera kagayidwe kachakudya matenda a mtima. Mankhwalawa ndi othandizira makamaka kuphatikiza ma pathologies awa, omwe nthawi zambiri amapezeka mwa odwala okalamba. Kuchita bwino kwa "Meldonium" kukufotokozedwa ndikuti kumathandizira kukulitsa kwa mitsempha yamagazi ya microvasculature ndikuwongolera kayendedwe ka ATP ndi oxygen, zomwe ndizofunikira pakudya mokwanira kwa maselo amitsempha ndi maselo am'mnyewa wamtima. Ndimagwiritsanso ntchito bwino mankhwalawa mankhwalawa ovuta a VVD, polyneuropathies, zotsatira za kuvulala pamutu ndi matenda ena amitsempha. Choyamba, ndikulembera mankhwalawo mu jekeseni wa 5.0 - 10,0 kudzera m'mitsempha N 10, kenako m'mapiritsi 250 mg kawiri pa tsiku kwa mwezi wina. Mankhwalawa atatha, odwala amawona kuchepa kwa chizungulire, kusasangalala mu mtima, kuchepa kwa magazi, kuchepa kwa dzanzi m'manja ndi m'miyendo, kuwonjezeka kwa magwiridwe antchito, komanso kuwonjezeka kuzolowera kupsinjika kwa thupi ndi kwamaganizidwe.

Nthawi zina odwala omwe ali ndi phosiposic kapena asthenic physique, omwe poyamba anali ndi kuthamanga kwa magazi, kuchepa kosafunikira kwa magazi kumawonedwa.Nthawi zina, odwala omwe ali mgulu lotsatira la mankhwalawo anali ndi mawonekedwe owoneka a dyspeptic, omwe, makamaka, adakonzedwa mothandizidwa ndi gastroprotectors.

Mankhwala ali ndi zoyipa ndi contraindication. Tengani zokhazo zomwe dokotala wakupatsani.

Mankhwala amalekeredwa bwino. Ndikulembera odwala omwe ali ndi mtima wodwala, ngati sichotsutsana. Odwala pazaka zilizonse amalolera bwino. Ndimakonda mphamvu yofewa komanso yokhalitsa. Kungoyenera kutsatira malangizo ndikutenga mwezi umodzi. Mutha kuyamba kutsitsa iv, kenako mumapikapu.

Mankhwala omwe alibe chithandizo chofunikira kwambiri chachipatala samaphatikizidwa muzitsogozo zamankhwala zakunja zilizonse. Zotsatira zoyesereratu za placebo, zomwe zimayesa kudzipangira zokha pakulimbitsa thupi, sizinawone zotsatira zake.

Osataya ndalama zanu pachabe.

Bwino kutsatira zakudya zoyenera, kugona ndi kuchita masewera olimbitsa thupi.

Sindinasangalale ndi zoti madokotala ndi odwala ena amawona masewera akungodzipangira ngati mankhwala.

Meldonium sinapangidwe kuti ichiritse matenda. Umboni wake mu zamtima mulibe. Ndikukayikira kuti pokhudzana ndi zamtundu wina, nazonso.

Ngati mukufuna mphamvu yakanthawi ndikuwonjezera ntchito pakukweza thupi - ndiye, mwina, meldonium ichita. Ochita masewera akudziwa izi. Koma izi sizitanthauza kuti meldonium "amachiritsa" china.

Posachedwa, adayamba kupereka mankhwala ndi Meldonium. Makamaka, ndinayesa kulimbikitsa kumwa mankhwalawa kwa wodwala yemwe ali ndi mtundu wa amyotrophic lateral sclerosis (nthawi zambiri ndimatenda omwe amapita patsogolo mwachangu), ndipo, chodabwitsa changa, wodwalayo adazindikira zabwino za mankhwalawa. Kuphatikiza apo, mankhwalawo ali ndi mtengo wotsika mtengo.

Mankhwala okwera mtengo, odwala adazindikira zabwino zosiyanasiyana. (M'mikhalidwe yovuta komanso yamavuto). Kuwonjezeka kwa mphamvu ndi kusintha pang'ono kwamaonekedwe zinaonekera. Amawonjezera kupirira ndi zolumikizana zamtima.

Pamafunika kuyeserera koyambirira kwa dokotala wa othandizira ndikuwongolera kuvomereza.

Zotheka

Zotsatira zoyipa pakugwiritsa ntchito sizimachitika kawirikawiri. Koma nthawi zina pamakhala kusokonezeka kwa mtima ndi dongosolo lamanjenje, khungu komanso kugaya chakudya. Amawoneka ngati awa:

• tachycardia
• Kusiyana kwa kuthamanga kwa magazi,
• dziko lokondwa
• mawonekedwe owoneka
• redness, kuyabwa ndi kutupa kwa khungu.

Ngati kugwiritsa ntchito Meldonium sikutheka, amaloledwa ndi mankhwala omwe ali ndi kapangidwe kofananako kapena kagwiritsidwe kofananako.

Zapangidwe

Mumsika wa pharmacology, mumakhala ma analogues ena monga Meldonium:

1. Medatern. Mankhwalawa amaperekedwa mu mawonekedwe a kapisozi. Amagwiritsidwa ntchito pakuchepa kwa mphamvu yogwira ntchito, kupsinjika kwa malingaliro ndi thupi, matenda amtima ndi mitsempha yamagazi, kusokonezeka kwa magazi muubongo. Makapisozi okhala ndi 250 mg yogwira ntchito angagulidwe ma ruble 300-350.
2. Mildronate Mankhwala opangidwa kuti apititse patsogolo kagayidwe, mphamvu zamagetsi. Amapezeka m'mapiritsi ndi mawonekedwe a yankho. Ili ndi zisonyezo ndi malire omwe angagwiritsidwe ntchito ngati Meldonium. Mtengo wapakati wa mankhwalawa: ma ruble a 600-700. - Makapisozi 60 okhala ndi 500 mg yogwira ntchito, pafupifupi ma ruble 300. - Makapisozi 40 okhala ndi 250 mg ya Meldonium. Mtengo wa yankho ndi 355-370 rubles.

Palinso mitundu ina ya Meldonium - Vasomag, Midolat. Mfundo zoyendetsera, zisonyezo ndi zoletsa ndizofanana kwa iwo. Mankhwalawa amasiyana m'dziko lomwe adachokera komanso mtengo wake.

Kukonzekera ndi mfundo yofananira

Mndandanda wazomwe zikuyimira pazomwe zimaperekedwa zikuphatikizapo:

Preductal ndi anti-ischemic, antianginal mankhwala. Gawo lake lalikulu ndi trimetazidine dihydrochloride. Amapezeka m'mapiritsi okhala ndi 20 kapena 35 mg yogwira mankhwala.

Amagwiritsidwa ntchito mu mtima, ophthalmic ndi otolaryngological zochita: ndi angina pectoris, zovuta za chorioretinal ndi vestibulo-cochlear zovuta za chikhalidwe cha ischemic. Osavomerezeka kwa ana, amayi oyembekezera komanso amayi oyamwitsa. Mtengo wapakati wa mankhwala ndi ma ruble 1700.

Riboxin ndi mankhwala osakhala a steroidal okhala ndi metabolic, antiarrhythmic ndi antihypoxic. Amagwiritsidwa ntchito pamavuto amisala yamtima, atherosulinosis, matenda am'mtima, poyizoni mowa, zilonda zam'mimba ndi m'mimba.

Mankhwala amathandizira kagayidwe, kusintha kagayidwe kakang'ono ka magazi ndi mpweya, kumawonjezera kulimba kwa thupi pakuchita masewera olimbitsa thupi. Mtengo wa malonda umachokera ku ma ruble 20. (zimatengera mtundu wa kumasulidwa).

Mexicoidol - imapezeka mu mawonekedwe a yankho, mapiritsi, komanso mano. Amalembedwa kwa odwala omwe ali ndi VVD, atherosulinosis, ngozi ya ubongo, matenda a mano (phala) ndi matenda omwe minofu ya hypoxia imachitika. Mutha kugula mankhwala otsukira mano kwa ma ruble 200. Mtengo wa mapiritsi ndi yankho limachokera ku 256 ndipo kuchokera ku ma ruble 506, motsatana.

Musanalowe m'malo a Meldonium ndi ma analogues oyendetsedwa kapena mankhwala omwe ali ndi mfundo yofananira, ndikofunikira kukaonana ndi dokotala.

Umboni wa odwala za meldonia

Zaumoyo kwa onse! Ndikufuna kuyika masenti anga 5 a "Meldonius"! Nthawi yoyamba yomwe ndidamwa maphunziro a masiku 30 a 1000 mu 2017! Zotsatira zake zinali zabwino! Popeza kuti kulibenso mphamvu zochoka pabedi, kale pa tsiku lachitatu ndinakwera bizinesi, ngati munthu wameza! Kenako ndinali ndi zaka 60, miyezi isanu ndi umodzi ndidapitilira maphunziro, koma 500 patsiku. ndipo sindimamva changu! Komabe, ndikulimbikitsa iwo omwe akuvutika ndi kufooka komanso depresnyakom! Tsopano pali yopangidwa ndi Russia, yogula kale ndikuyamba kutenga! Kuphuka, kuperewera kwa vitamini, ulesi ndi zina zomwe zimabweretsa ndi zilonda zam'mimba! Boom nkhondo? Boom!

Ndimagwira ntchito usiku, ndimatenga Meldonium nthawi zina 25-30 makapisozi 250 patsiku, amathandizira kuti asagone. Ngakhale palibe mavuto, ndimatenga mwezi.

Anadutsa njira ya jakisoni 10 kudzera m'mitsempha. Panali zoopsa m'malo a mtima. Kukanikiza, kupweteka kwa ululu, kufupika pakulimbitsa thupi, kufooka m'mawa. Atatha ECG, adotolo adapereka majekeseni a Meldonium. Kuleza mtima ndikwabwino, kunalibe mavuto. Nditangolandira jakisoni, ndinamva mwayi wopumira kwambiri. ECG yobwerezedwa idawonetsa kusintha kwakukulu. Pakumayambiriro, chaka chotsatira, atavomerezedwa ndi dokotala, adabwereza maphunzirowo. Yothandiza.

Anthu omwe amalankhula zopanda pake kwa mankhwalawa ndi abodza. Kapenanso musavutike kuwerenga malangizo. Ndinagula makapisozi 40 mgulu la 250 mg. Ndimamwa makapisozi 2 m'mawa. Mlingo wa wothamanga wamasewera ndi magalamu 0,5 okha patsiku. Mphamvu yowoneka kwambiri. M'mbuyomu, zinali zovuta kwambiri kuti ndiziyang'anira bizinesi yanga komanso kuchita masewera olimbitsa thupi nthawi yomweyo. Tsopano nditha kuchita bizinesi ndi masewera tsiku lililonse. Sichikhala kale zowawa komanso kuchepetsa minofu. Ndikaweruka kuntchito, ndimatha kuthamanga ndikukwera njinga kwa ma kilomita 8-12. Kapena pitani kukaphunzitsidwa mphamvu. Zina zomwe ndidazindikira - njira yothandizira kupuma komanso kuperekera kwa okosijeni ndi magazi ndiyabwino. Momwe ndimapumira pang'ono, ndayamba kale kutha. Kumene nthawi zambiri sindimatha kuthawirako chifukwa chopanda mphamvu, tsopano ndikuthamanga. Masewera adayamba kubweretsa chisangalalo, ndipo osakhala ufa usanachitike kapena utamaliza ntchito yonse yopatsa mphamvu. Mlingo 0,5 g patsiku. Ndipo osapitilira 1 gramu ya prof. othamanga! Kupanda kutero, sipakhala zotsatira.

Ndinaphunzira zaka ziwiri zapitazo ndipo ndinali ndi nkhawa kwambiri komanso ndimavutika kwambiri. Kuyankhulana ndi dokotala, ndidamufunsa za mankhwalawa komanso ngati zingandithandizire polimbana ndi nkhawa komanso kutopa. Adandipatsa yankho labwino ndipo adati ichi ndi chida champhamvu chogwedezera thupi lanu. Ndimayamika dokotala uyu. Kupsinjika komwe kwatsalira, ndipo malingaliro abwino adadzalowa m'malo mwake, komanso kufunitsitsa kuchitapo kanthu ndikuyenda! Zachidziwikire, Meldonium ndiyothandiza ndipo palibe njira yochizira mankhwalawa kwambiri. M'pofunikanso kunena kuti muyenera kutsatira malangizo ogwiritsira ntchito Meldonium. Mankhwala osokoneza bongo amakutsogoletsani mkhalidwe woipa. Chifukwa chake, ngati ndinu wolimbikira ntchito ndipo mulibe katswiri wazolimbitsa thupi, ndipo mukuvutika ndi kutopa ndi kukhumudwa, ndiye kuti Meldoniy angokupangitsani kukhala bwino!

Ndili kuchipatala cha mtima. Kusokonezeka kwa kayendedwe ka mtima, fibrillation pamaso pa thyrotooticosis. Mobwerezabwereza. Nthawiyi, potaziyamu mankhwala enaake okhala ndi meldonium adayikidwa. Pa tsiku lachiwiri ndinamva kusintha. Pambuyo masiku 10 ndi ECG yowongolera pali kusintha. Ndikupangira!

Ndimalephera kugwiritsa ntchito mankhwala osokoneza bongo komanso matenda oopsa. Nthawi ndi nthawi ndimayeserera mankhwala atsopano. Ndidayesa Meldonium. Pa tsiku lachiwiri, arrhythmia, tachycardia, masomphenya osawoneka adawonekera. Kupsinjika kunatsikira mpaka ku 160. Ndili ndi vuto pambuyo pakuthira mankhwala othandizira. "Meldonium" ndizosangalatsa. Ndikuyamwa, ndidagona bwino kwambiri. Kotero izi sizachidziwikire, koma sizinkandiyendera. Ndili ndi sabata limodzi lokha. Ndiyesanso pamlingo wotsika komanso m'mawa wokha.

Ndimamwa "Mildronate" kuchokera ku osteochondrosis ya msana, imathandiza, koma muyenera kumwa malinga ndi malangizo osachepera mwezi, chizungulire ndi kufooka zimachoka, ndipo mutu wanga ukumveka. Ndinaikamo majekeseni 10 m'mitsempha, kenako mapiritsi. Ndikoyenera kuyesa.

Ndimagwira ntchito zolemetsa ngati "ankachita masewera", mokondweretsa. Mitundu ina yowonetsera pompopompo sikuyenera kuyembekezeredwa, koma zizindikiro zamphamvu zakula bwino, kuchira pambuyo pakuphunzitsidwa kumachitika mwachangu, mkhalidwe wamthupi watukuka. Ndili ndi zaka 43.

Mankhwala abwino! Anandibwezeretsa ku moyo! Mphamvu zidachulukirachulukira! Chaka chatha ndidamaliza maphunziro mu kasupe, tsopano ndikubwereza!

Ndipo chaka chimenecho ndidazindikira chomwe Meldonius ali, pomwe adayamba kukambirana za othamanga. Sindinadziwe chomwe chinagulitsidwa ku pharmacy. Ndinazindikira, ndinayesa. Ichi ndiye chipulumutso changa. Chowonadi ndi chakuti m'zaka zaposachedwa matenda amtundu wanga akuipiraipira. Ngati khomo lachiberekero makamaka, kenako kufooka thupi lonse. Ndimamva ngati wokalamba. ali ndi zaka 43. Chifukwa chake "Cardionate" (meldonium) tsopano wandipulumutsa. Zimapatsa mphamvu, ndikhala ndi moyo tsopano. Ndamwa ma CD. Ndimamva bwino. Komanso mpaka kufalikira kotsatira (kuchokera posowa tulo komanso kutopa kwambiri). Ndimaganiza kuti amangopatsa mphamvu, zimapezeka kuti zilonda zimadutsa mwachangu. Ndipo madokotala amangoyang'ana pa ntchito zake. Ndipo ambiri angathe kuzichita. Contraindication, ngati, kokha arrhythmia ndi matenda a impso ndi chiwindi. Chaka chimenecho, ndikupita kwa a neuropathologist kuti apangana ndi cervical chondrosis, ndidachotsa kukokoloka ndi meldonium ndikumuuza. Mwina adzalangiza ena.

Meldonium imakhala ndi zotsutsana pamthupi la othamanga. Kuthekera kwake kopititsa patsogolo kukhudzika kwa anthu athanzi alibe umboni wokwanira. M'mayeso amodzi okha opangidwa ndi okalamba omwe ali ndi zaka zopitilira 60 ndi angina pectoris, meldonium adawonetsa kuyeserera pakuchita zolimbitsa thupi.

Nthawi zonse ndimagwira ntchito molimbika, ndimaganiza kuti sindidzatopa, koma ana atatu ndi womaliza maphunziro, mwachidziwikire, adachita chinyengo. Amamva kusayenda bwino kwamtima, ECG idawulula choletsa chinthucho. Zinakhala zowopsa pa 37. Dotolo wodziwika ndi meldonium, wolimbikitsidwa kuposa khofi, wakhazikika ndi mphamvu, ndichisoni maphunziro ake adzatha posachedwa. Mankhwala a supermen, ndidathandizadi.

Ndili ndi mikwingwirima iwiri, Ndameza miyala yofewa m'matumba mpaka ndidazindikira - zonsezi ndizopanda pake. Mapiritsi osagwira ntchito.

Tikumanga nyumba ndi mchimwene wanga, makamaka tokha. Anayamba kusasangalala, adapita kwa dotolo, ndipo adapezeka kuti watopa kwambiri komanso watopa. Analimbikitsa kuti agone m'chipatala kwa sabata limodzi. Anandibaya ndi mankhwala "Meldonium." Mankhwala abwino kwambiri, mphamvu zimabweranso pamaso pathu. Pambuyo pa masiku angapo ndinali wathanzi komanso wamphamvu, komabe ndinakakamizika kulandira chithandizo mpaka kumapeto. M'masiku awiri oyamba, chowonadi chinapatsidwanso dontho la shuga, koma "Meldonium" wandithandiza kwambiri. Tsopano ndagulanso mapiritsi - Ndizomwera pakakhala katundu wolemera.

Ndadziwa ndikugwiritsa ntchito Meldonium kwa nthawi yayitali. Popeza kuti analogi yolowera pamalowo ndi yokwera mtengo kwambiri, ndipo mankhwalawo amandithandiza bwino, ndinayenera kupeza ina. Ndikufuna kudziwa makamaka momwe meldonium ikuwongolera magwiridwe antchito - zimandikhudza bwino kwambiri! Ingotsimikizirani kuti muyambe kukambirana ndi katswiri wazamtima.

Kufotokozera kwapfupi

Meldonium ndi chinthu chogwira ntchito cha mankhwala otchuka a Mildronate (adzalembedwe pano mosiyana), amenenso ndi mankhwala odziimira pawokha opangidwa ndi fakitale yopanga mankhwala ku Pharmstandard. Meldonium imayamba pa cellular kusinthika kwakukhudzana kwa zamankhwala, zochitika ndi kusintha komwe kumakhudza kagayidwe kazakudya ndikulola kugwiritsa ntchito mankhwalawa onse mu njira ya "solo" komanso monga gawo la chithandizo chophatikizidwa m'malo osawoneka bwino kwenikweni, mankhwalawa mtima ndi ocular matenda, mankhwalawa achire zizindikiro ndi kukonza asthenic zinthu. Makina ochitapo kanthu a mankhwalawa sangathe kumvetsetsa kwathunthu ndi munthu yemwe sanadziwike zinsinsi zazachilengedwe: meldonium imalepheretsa enzyme gamma-butyrobetaine hydro oxygenase, yomwe imakhudzana ndi kapangidwe ka carnitine, zomwe zimapangitsa kuti pakhale kuchuluka kwa gamma-butyrobetaine, yomwe ili ndi zinthu zopanda pake. Koma izi sizopindulitsa zonse za meldonium: imalepheretsa kuyenda kwamafuta amtali kudzera mu membrane ya cell, imathandizira kupezeka komanso kuwonjezereka mu maselo a mitundu yogwira ya mafuta acids, omwe ndi acyl coenzyme A ndi acyl carnitine. Ndipo ngati sichidziwika bwino kwa owerenga ambiri kuti ndi mtundu wanji uwu, ndiye kuti muyenera kukhala oleza mtima ndikupitilizabe kuwerenga. Chimodzi mwazinthu zazikulu kwambiri zokhudzana ndi meldonium ndikukonzanso kwa kusakanikirana pakati pa kuperekera kwa okosijeni ku maselo ndikuwadyedwa pansi pazovuta za ischemia (The Great Soviet Encyclopedia imapereka tanthauzo lolondola komanso lomveka bwino la matenda amtunduwu - magazi m'deralo).

Mankhwala amaletsa kuphwanya kayendedwe ka gawo lalikulu lamphamvu la khungu - ATP, pomwepo ndikuyambitsa anaerobic glycolysis. Ndi ischemia ya minofu ya mtima, meldonium imachedwetsa mapangidwe a necrosis zone, amafupikitsa nthawi yokonzanso. Kugwira ntchito kwa mtima kosakwanira, kumakulitsa kukhudzika kwa minofu ya mtima, kumapatsa wodwalayo mphamvu yolekerera yolimba, ndikuchepetsa pafupipafupi angina pectoris. Pa gawo lodzizindikira, meldonium imawonjezera kugwira ntchito, imayendetsa dongosolo lamkati lamanjenje, imayendetsa chitetezo chokwanira, komanso imachepetsa kupsinjika kwakuthupi ndi kwamaganizidwe.

Meldonium imapezeka mu mawonekedwe a makapisozi ndi yankho la jakisoni. Fomu ya pakamwa imatengedwa musanadye.Mlingo, pafupipafupi komanso kutalika kwa makonzedwe zimatsimikizika ndi matenda enaake ndipo zimatha kukhala zosiyanasiyana: mwachitsanzo, nthawi ya meldonium mu mtima kulephera, ngozi yokhazikika ya angina pectoris kapena matenda a cerebrovascular is 4-6 milungu, ndi cardialgia - masiku 12, kusiya mowa - 7-16 Masiku 10, ndi kuchepetsedwa magwiridwe antchito komanso monga thandizo mu masewera - masiku 10-21.

Pharmacology

Metabolism enhancer, gamma-butyrobetaine analogue. Imalepheretsa gamma-butyrobetaine hydroxynase, imalepheretsa kaphatikizidwe ka carnitine ndi kayendedwe ka mautali amafuta ambiri kudzera mumitsemvu yama cell, ndikulepheretsa kudzikundikira kwa mitundu yamafuta yama asidi mu maselo - zotumphukira za acylcarnitine ndi acylcoenzyme A.

Mikhalidwe ya ischemia, imabwezeretsa bwino momwe magwiritsidwe ntchito a mpweya ndikuperekera ma cell, imalepheretsa kuphwanyidwa kwa kayendedwe ka ATP, ndipo nthawi yomweyo imayambitsa glycolysis, yomwe imachitika popanda kugwiritsa ntchito mpweya. Zotsatira zakuchepa kwa ndende ya carnitine, gamma-butyrobetaine yokhala ndi masodilating amapangidwe kwambiri. Limagwirira ntchito limazindikira kusiyanasiyana kwake zotsatira zake zamankhwala: kuwonjezeka kwa mphamvu, kuchepetsa mphamvu ya kupsinjika kwa malingaliro ndi thupi, kutseguka kwa minofu ndi kusakhazikika pakulimbitsa thupi, mtima.

Pankhani ya kuwonongeka kwa pachimake kwa ischemic ku myocardium, kumachepetsa mapangidwe a necrotic zone ndikufupikitsa nthawi yokonzanso. Ndi kulephera kwa mtima, kumawonjezera kuchepa kwa mtima, kumathandizira kulolerana, komanso kumachepetsa pafupipafupi matenda a angina. Mu pachimake komanso matenda a ischemic matenda amitsempha yamagazi amatulutsa magazi mozungulira ischemia, amathandizira kugawa magazi mokomera dera la ischemic. Kugwiritsa kwa mtima ndi dystrophic matenda a fundus. Imakhala ndi kukhudzika kwa chapakati mantha dongosolo, amachotsa magwiridwe antchito a mantha amthupi mwa odwala omwe ali ndi uchidakwa woperewera.

Zotsatira zoyipa

Kuchokera pamtima dongosolo: kawirikawiri - tachycardia, kusintha magazi.

Kuchokera kumbali ya chapakati mantha dongosolo: kawirikawiri - psychomotor mukubwadamuka.

Kuchokera pamimba yogaya: kawirikawiri - zizindikiro za dyspeptic.

Thupi lawo siligwirizana: kawirikawiri - kuyabwa pakhungu, redness, zidzolo, kutupa.

Kwa pakamwa kapena mtsempha wa magazi: monga mbali ya zovuta za matenda a mtima (kuphatikiza mu osewera), nthawi yothandizirana kuti ipititse patsogolo kukonzanso, matenda obwera chifukwa cha uchidakwa wophatikizana ndi mankhwala ZMA).

Mwa makonzedwe a parabulbar: kusokonezeka kwakukulu kwa mitsempha m'matumbo a retina, hemophthalmus ndi retinal hemorrhages a etiology osiyanasiyana, thrombosis ya chapakati kwamitsempha yam'mimba komanso nthambi zake, retinopathy yamitundu yosiyanasiyana (kuphatikizapo diabetes komanso hypertonic) - pokhapokha pakayendetsedwe ka parabulbar.

Kodi Meldonium ndi chiyani?

Meldonium, yomwe imadziwikanso kuti Mildronate, ndi mankhwala omwe amafulumizitsa kagayidwe ka thupi. Idapangidwa kale mu 1975 ndi pulofesa wa zamankhwala azachipatala, Ivar Kalvins, yemwe masiku ano ndi mutu wa imodzi mwa madipatimenti a Latvia Institute ku Riga. Pakufufuza kwake, a Kalvins adapeza chinthu china chapadera, chomwe ndi gamma-butyrobetaine, chomwe chili ndi chofunikira chogawa zinthu zama cell ngati thupi liziwonjezedwa nthawi zonse. Modma-butyrobetaine wosinthidwa wapanga maziko a Meldonium dihydrate, yomwe ndi gawo lalikulu la Mildronate.

Kapangidwe ndi mfundo zoyenera kuchitidwa ndi Mildronate

Chiyambireni, Mildronat wabweretsa chidwi pakati pa ankhondo ndi othamanga - onse masewera ndi akatswiri. Inkagwiritsidwa ntchito kwambiri pafupifupi m'maiko onse a post-Soviet, chifukwa anthu anali ndi chikhulupiliro chazinthu zodabwitsa za Meldonius, makamaka, kuthekera kwake kokweza mphamvu zamthupi komanso kuthamanga kwa kuzindikira kwa anthu. Komabe, palibe umboni wa asayansi pankhaniyi.

Komabe, mu 2016, Mildronate adadziwika kuti ndi mankhwala omwe amaletsedwa kwa osewera pamasewera akulu. Nthawi yomweyo, kutchuka kwa mankhwalawa pakati pa anthu wamba kwachuluka. Kufunika kosasinthika kwa Mildronate chifukwa cha mankhwala ake.

Chifukwa chake, zinthu zofunikira za Meldonium zimaphatikizaponso kuthekera kwake kuteteza minofu ya mtima kuti isavalidwe kwambiri. Munthawi iliyonse ya moyo wa munthu, mphamvu zimatha, ndiye kuti mphamvu zamkati zamthupi zimawotchedwa. Zida izi zimapangidwa ndi mafuta ndi glycogen. Thupi likagwira ntchito kwanthawi yayitali pamlingo wopatsa mphamvu, maselo amayamba kuvutika chifukwa chosowa mpweya, ndipo kuchepa kwa michere sikothandiza. Kuchita glycogen kumafuna kuyeserera pang'ono, pomwe mafuta amawotchera pang'onopang'ono. Ndi vuto la kuperewera kwa okosijeni, maselo alibe nthawi yosinthira mafuta, ndichifukwa chake thupi "lotsekedwa" ndi zinthu zovunda zowonongeka. Izi zimabweretsa chiopsezo cha matenda osiyanasiyana a mtima, mwachitsanzo, matenda a mtima.

Mildronate salola mafuta kuti azikonzedwa ngati wina akumana ndi vuto la oxygen. Imayambitsa kusweka kwa glycogen, potero imatulutsa mphamvu mwachangu ndikusungira zatsalira za oxygen m'maselo. Mwachidule, malo a Meldonium ndikuyika munthu m'njira yopulumutsa mphamvu ndikulola kuti thupi lizigwira ntchito osavulaza mtima.

Komabe, zopindulitsa za Mildronate sizingokhala ndi izi. Mankhwalawa atha kubweretsa zabwino zambiri m'masewera, komanso othandizira pakuchiza matenda osiyanasiyana.

Ubwino wa Mildronate kwa abambo ndi amayi

Popeza katundu wa Meldonium amathandizira kupirira kupsinjika kwakuthupi popanda kuvulaza thanzi, limagwirizana ndi kupewa ischemia limodzi ndi akatswiri odziwa ntchito. Kuphatikiza apo, imateteza maselo amtima kuti asamavute pasadakhale, kumawonjezera kukana kwaumunthu pamavuto ndi kupsinjika.

Njira zina zochizira Mildronate zimaphatikizaponso kuthamangitsa magazi mu ubongo ndi retina, mogwirizana ndi zomwe nthawi zambiri amalembera kupewa magazi.

Malangizo oyendetsera ndi muyezo Mlingo wa Mildronate

M'mafakitala ambiri, Mildronate angagulidwe mumitundu yosiyanasiyana: amagulitsidwa mumapiritsi ndi mapiritsi a 250 ndi 500 mg, komanso monga njira yothetsera jakisoni. Mukamamwa mankhwalawa, muyenera kutsatira mosamala malangizo kuti muchepetse chiopsezo cha zovuta zoyipa. Mlingo wa Mildronate zimatengera cholinga chake. Mutha kuwerengera nokha mlingowo, pa 20 mg wa Mildronate pa 1 kg yolemera, koma ndibwino kufunsa akatswiri poyamba.

Kugwiritsa ntchito kwa Mildronate

Mildronate amagwiritsidwa ntchito ndi anthu azaka zopitilira 18 pazikhalidwe zosiyanasiyana zathanzi, ngakhale atakhala kuti ndi amuna kapena akazi. Monga lamulo, limalembedwa kwa othamanga kapena ogwira ntchito zamaganizo, koma limadziwikanso kwa omwe ali ndi vuto la matenda osokoneza bongo komanso kusokonezeka kwa dongosolo la mtima, matenda oopsa komanso anthu omwe amadalira mowa.

Kwa othamanga

Mapindu a Mildronate adzayamikiridwa makamaka ndi okonda moyo wokangalika. Imabwezeretsa kagayidwe ka oxygen m'misempha panthawi yophunzirira mwakhama, imalepheretsa kudziunjikira kwa poizoni komanso zotayidwa kuchokera ku cellular metabolism, komanso kuteteza maselo kuti asawonongedwe mwadzidzidzi.

Kubwezeretsa mphamvu, othamanga ayenera kumwa makilogalamu 250 mg kanayi pa tsiku kwa masabata awiri. Phindu looneka lidzabweretsanso maphunziro a jekeseni a 2 a Mildronate - 500 mg kamodzi patsiku.

Ndi zidakwa

Meldonium imakhala ndi zotsatira zabwino pakatikati patimatenda amanjenje ndipo nthawi zambiri imagwiritsidwa ntchito polimbana ndi kudalira mowa, chifukwa imathandizira kukhazikika pamalingaliro am'maganizo komanso imathandizira kupirira Zizindikiro za "draal syndrome".

Zochizira zakumwa zoledzeretsa, Mildronate amagwiritsidwa ntchito pa mlingo wa 500 mg. Amatengedwa kanayi pa tsiku kwa masabata 1 mpaka awiri.

Jakisoni wa Mildronate amakhalanso ndi chithandizo chamankhwala. Panthawi imeneyi, njirayi imagwiridwa 2 pa tsiku pa 500 mg panthawi yomweyo.

Ndi mtima arrhythmias

Mildronate watsimikizira kufunikira kwake pangozi zapamtima. Zimawonjezera kuchuluka kwa kugunda kwa mtima, potero kuletsa kukula kwa angina pectoris, kusintha magazi. Pofuna kupewa matenda a mtima, Mildronate amagwiritsidwa ntchito m'mapiritsi a 0,5 - 1 g patsiku. Nthawi yolimbikitsidwa ndi 1 - 1.5 miyezi.

Kuchokera kutopa

Mildronate amathandizidwanso kuti azitha kutopa kwambiri komanso kuwonjezeka chifukwa chokhala ndi nkhawa komanso thupi. Phindu lake pamatenda amenewa ndi kukhathamiritsa magazi ndi okosijeni, chifukwa chakuchulukitsidwa kwa ntchito, munthu amakhala wolimba komanso amakhala ndi zovuta zina.

Kodi ndizotheka kuchepetsa thupi mothandizidwa ndi Mildronate

Nthawi zina, mapiritsi a Mildronate amagwiritsidwa ntchito pochotsa mapaundi owonjezera, koma pamenepa, muyenera kusamala mukamamwa mankhwalawo kuti m'malo mopindulitsa, musavulaze thupi. Zomwe Meldonium imathandizira kuchepa kwa thupi chifukwa cha kayendetsedwe ka kagayidwe, koma siyivomerezedwa mwapadera kutiigwiritse ntchito ngati chida chodziimira nokha! Mildronate ali ndi zotsatira zoyenera kuphatikiza masewera olimbitsa thupi komanso kudya mokwanira.

Zotsatira zoyipa ndi Mildronate

Mwa zabwino zake zonse mthupi laumunthu, Mildronate imatha kuvulaza kwambiri thupi ngati mupitilira muyeso kapena kuudya popanda malangizo a dokotala. Meldonium ili ndi mndandanda wautali wazotsatira zomwe zingayambitse mavuto ambiri. Komabe, zimawoneka kawirikawiri, ndipo malinga ndi malamulo ogwiritsira ntchito, kuvulaza kuchokera kwa iwo kumachepetsedwa. Mwa zina mwa mbali mwa Mildronate ndi monga:

• malamba, kutentha kwache,
• kusanza ndi kusanza
• kulemera m'mimba
• tachycardia
• hypotension
• kutupa ndi zotupa,
• khungu lawo siligwirizana,
• kuyabwa

Kuphatikiza apo, Mildronate ndiyowopsa m'mawu a akatswiri: osewera, kugwiritsidwa ntchito kwake kungakhale kodzaza ndi kusayenerana ndi mpikisano, chifukwa Meldonium ndi amodzi mwa mankhwala oletsedwa a WADA.

Kugwirizana kwa Mildronate mowa

Pakadali pano, palibe zotsutsana mwachindunji ndi kugwiritsa ntchito Mildronate kuphatikiza mowa. Komabe, ambiri ogwira ntchito zachipatala salimbikitsa kuphatikiza Meldonium ndi zinthu zomwe zili ndi mowa kuti mupewe mavuto. Mowa ungasokoneze phindu la mankhwala, ndipo nthawi zina magwiritsidwe a Mildronate angayambitse kuchuluka kwa kuledzera ndikupangitsa kudumpha m'magazi. Kwa thupi lamunthu wathanzi, ndizotheka kuti sipangakhale vuto lililonse kuchokera kuphatikiza kwa Meldonium ndi mowa, koma kusintha koteroko sikungapindulitse odwala omwe ali ndi matenda oopsa.

Analogs a Meldonium

Mwakutero, ma analogues a Mildronate pakadali pano kulibe, ngakhale kuyesera kuti mupeze wothandizira wina yemwe ali ndi malo omwewo samayima. Mwa kuchuluka kwakukulu kwa zinthu, trimetazidine imatha kudziwika, yomwe ntchito zake ndi zofanana ndi Meldonium, ndiko kuti, kukondoweza kwa kagayidwe, koma lingaliro lake limagwira mosiyanasiyana. Kuphatikiza apo, amadziwikanso ngati mankhwala oletsedwa pamasewera.

Koma, ngakhale ali ndi mbiri yachisoni, Meldonium imatha kupezeka m'masitolo ogulitsa mankhwala, komanso mitundu ina yambiri ya mankhwala, omwe amaphatikizira gawo la Meldonium dihydrate. Zina mwa izo ndi:

• Angiocardyl
• Vasomag,
• Idrinol
• Cardionate
• Medatern
• Midolat
• Mildroxin ndi ena.