Insulin Tujeo SoloStar yatsopano: ndemanga za anthu odwala matenda ashuga

Insulin yatsopano imapereka chitetezo champhamvu kwambiri cha glycemic mkati mwa maola 24 ndi chiopsezo chochepa cha hypoglycemia poyerekeza ndi
Ndi mankhwala Lantus ,,,

Moscow, Julayi 12, 2016 - Kampani ya Sanofi yalengeza kulandira satifiketi yolembetsa ku Russia ya mankhwalawa Tujo SoloStar ® (insulin glargine 300 IU / ml), insulin insulin yayitali ikuvomerezedwa kuti igwiritsidwe ntchito pochiza matenda amtundu wa 1 ndi mtundu wa 2 wa akuluakulu. Gulu loyamba la insulin yatsopano likuyembekezeka ku Russia mu Seputembara 2016.

Malinga ndi NATION All-Russian Epidemiological Study ku Russia, odwala pafupifupi 6 miliyoni omwe ali ndi matenda a shuga a 2. Oposa 50% odwala samachita bwino kwambiri m'magazi a glycemia.

“Kwa zaka pafupifupi zana limodzi, njira zochizira matenda a shuga zapangidwa. Munthawi yonseyi, sitinachite bwino pakubwezeretsa, komanso tinapeza zambiri za sayansi zomwe zimatsegula zatsopano za matendawa ndikupangitsa zolinga zamankhwala kukhala zofunitsitsa. Kubwera kwa mankhwala abwino pothana ndi matenda ashuga, timapeza chida chomwe chimatiloleza kukhazikitsa zolinga zakupambaniratu pochiza matenda ashuga, omwe cholinga chake ndi kupititsa patsogolo thanzi komanso moyo wa odwala athu. Masiku ano, mankhwalawa ndi insulin ya Tujeo, ndipo tili ndi mwayi wogwiritsa ntchito njira zake zopangira zamankhwala ku Russia. Malinga ndi deta yomwe ilipo kale, Tujeo ali ndi maubwino malingana ndi kuchuluka kwa kuchuluka kwa hypoglycemia komanso kusuntha kwa kulemera kwa thupi poyerekeza ndi insulin Lantus, komanso kusunga cholowa chake pokhudzana ndi chitetezo chamtima komanso chidziwitso cha oncological. Takhala ndi luso la zaka zambiri ndikugwiritsa ntchito insulin glargine 100 IU, lero tili ndi mwayi wodziwa mtundu watsopano wa glargine, "watero a MV Shestakova, Mlembi Wofananira wa Russian Academy of Sayansi, Mtsogoleri wa bungwe la matenda ashuga, FSBI ESC.

Kulembetsa mankhwala kwatsopano kwakhazikitsidwa pazotsatira za pulogalamu yofufuza zamankhwala ya EDITION, yomwe ili mndandanda wa mayeso akuluakulu apadziko lonse a III kuti athe kuwunika bwino komanso chitetezo cha Tujeo poyerekeza ndi Lantus, pomwe odwala opitilira 3,500 adatenga nawo gawo. Mu maphunziro, insulin yatsopano idawonetsedwa moyenera komanso mawonekedwe abwino otetezeka. Kugwiritsidwa ntchito kwa Tujeo kumayendera limodzi ndi chiopsezo chochepa cha hypoglycemia mwa anthu odwala matenda ashuga. Insulin yatsopano idawonetsanso mawonekedwe okhazikika pazochitika komanso kusinthasintha kwapakati pa glycemic poyerekeza ndi Lantus kwa maola 24 kapena kuposa 4.

"Kukula kwa insulin yatsopano pamakampani a kampaniyi ndikofunikira kwambiri pa mbiri ya matenda ashuga a Sanofi pafupifupi 100. Tipitiliza kupanga ndi kugulitsa mankhwala atsopano kuti tikwaniritse zosowa za anthu odwala matenda ashuga. Tujeo wokhala ndi mbiri yayitali kwambiri komanso yotalikilapo, yofanana ndi Lantus insulin ndikuyenda bwino, ingathandize kukulitsa odwala omwe akwaniritsa zofuna zawo .. Sitongopereka mankhwala atsopano pamsika wa Russia, komanso mwa dongosolo la Pharma 2020 Tinaliyika mu fakitale ya Sanofi-Aventis Vostok, kuyambira ndikulemba kwachiwiri mu 2016.Kuzungulira kwathunthu kwakonzedwera chaka cha 2018, ”adayankha Oksana Monzh, wamkulu wa mabizinesi okonzekera endocrine Sanofi Russia.

About Tujeo

Tujeo amaimira m'badwo waposachedwa wa insulin wakale. Mankhwalawa ali ndi katatu kuchuluka kwa magawo omwe amagwira ntchito mu 1 ml ya yankho (300 IU / ml), yomwe imasintha kwambiri5. Tujeo imapereka pang'onopang'ono insulini ndikutulutsa kwake pang'ono pang'onopang'ono m'magazi, komanso mphamvu yayitali, yomwe imayambitsa kuwongolera kodalirika kwamagazi a shuga kwa maola 24 ndi chiopsezo chotsika cha hypoglycemia poyerekeza ndi Lantus 1, 2, 3, 4.

Tujeo idavomerezedwa kuti igwiritsidwe ntchito m'maiko 5, m'maiko 34, kuphatikiza mayiko mamembala a EU, Iceland, Liechtenstein, Norway, Japan ndi USA.

About Sanofi

Sanofi ndi m'modzi mwa atsogoleri padziko lonse azamisala. Kampaniyo imapanga ndikugwiritsa ntchito njira zothetsera zomwe zimakwaniritsa zosowa za odwala padziko lonse lapansi. Sanofi wakhala akugwira ntchito ku Russia kwa zaka 45. Kampaniyo imagwiritsa ntchito anthu opitilira 2,000 ku Russia. Masiku ano, Sanofi ndi m'modzi mwa atsogoleri pamsika wama Russia wopereka mankhwala, kupatsa odwala ake mitundu ingapo yamankhwala oyamba monga ma shuga, oncology, matenda amtima, matenda amkati, matenda amkati wamanjenje, katemera komanso osowa matenda.

Za fakitale ya Sanofi-Aventis Vostok

Mu 2010, kampani yapamwamba kwambiri ya Sanofi-Aventis Vostok CJSC idakhazikitsidwa ku Oryol Region. Ichi ndiye chomera choyamba komanso chokhacho ku Russia kuti chipange insulin yotsogola kwambiri. Kukula kwa chomera ndikokwanira kukwaniritsa zosowa zamisika ya Russia ndi mayiko a CIS mu insulin yamakono. Mu Julayi 2015, chomera cha Sanofi-Aventis Vostok chadutsa bwino kuyesa kwa ku Europe ndikulandila setifiketi ya GMP ku European Medicines Agency (EMA), yomwe ingalore kutumiza kwa insulin komwe kumapangidwa ku Orel kupita ku mayiko a European Union.

Za matenda ashuga

Matenda a shuga ndi matenda oopsa osachiritsika, omwe amafala padziko lonse lapansi. Oposa 400 miliyoni padziko lapansi ali ndi matenda a shuga pakadali pano, ndipo pofika chaka cha 2040, malinga ndi akatswiri, chiwerengero chawo chidzaposa 640 miliyoni. Izi ndi pafupifupi mamiliyoni 10 miliyoni pachaka chilichonse.

Zambiri pa kuchuluka kwa anthu odwala matenda ashuga ku Russia mpaka posachedwapa zakhala zochepa kwambiri chifukwa cha kusowa kwa maphunziro akulu am'matenda, popeza momwe kalembedwe ka odwala kamakhudzidwira zimawerengera milandu yopezeka.

Chifukwa cha NATION, kafukufuku woposerapo waukulu kwambiri ku Russia, zambiri zomwe zidakwaniritsidwa zimapezeka koyamba pa mtundu 2 wa matenda ashuga ku Russia, omwe ndi 5.4%, ndiye kuti pafupifupi 6 miliyoni anthu 6. Mwa awa, opitilira theka sakudziwa za matenda awo, ndipo pafupifupi 40% ali pagawo lowalipira. Pafupifupi 20% yaanthu ali pachiwopsezo, popeza ali ndi prediabetes. Kafukufuku wa NATION adakhazikitsidwa ndi Federal State Budgetary Institution Endocrinological Research Center ngati gawo la chikumbutso chomwe chidasainidwa pakati pa Federal State Budgetary Institution of the National Science Center ndi Sanofi Russia pa February 28, 2013 ku Kremlin pamaso pa Purezidenti waku Russia V. Putin ndi France F. Hollande.

Matenda a shuga ali ndi ndalama zambiri. Pafupifupi 12% ya bajeti yonse yathanzi imagwiritsidwa ntchito pa matenda ashuga padziko lapansi. Matenda a shuga ndi zovuta zake ndi zina mwazomwe zimayambitsa kulumala ndi kufa kwa anthu, kuphatikizapo omwe ali ndi zaka zogwira ntchito. Ndalama zomwe amalipira odwala omwe ali ndi vuto la matenda ashuga ndizokwera kwambiri kuposa zolipira odwala popanda zovuta. Mfundo zazikuluzikulu zomwe zikuwongolera kuwongolera chuma cha matenda ashuga kukupitilizabe kupeza nthawi, komanso chithandizo chamankhwala chokhacho komanso chotetezeka ndi mankhwala amakono, kuphatikiza m'badwo waposachedwa wa insulin.

Development department Sanofi Russia
+7 (495) 721-14-00
[email protected]

Yki-Järvinen H, et al. Chisamaliro cha Matenda a shuga 2014, 37: 3235-3243.

Kunyumba P., et al. Kusamalira Matenda a shuga 2015, 38: 2217-2225.

Ritzel, R. et al. Matenda a shuga. Metab. 2015, 17: 859-867.

Becker RH, et al. Kusamalira Matenda a shuga 2015, 38 (4): 637-643.

Malangizo ogwiritsira ntchito Tugeo SoloStar®

Kafukufukuyu adachitika pachitukuko cha Federal State Budgetary Institution Endocrinological Sayansi Center (ESC) ya Ministry of Health of the Russian Federation mothandizana ndi Sanofi Russia kuti athe kuwunika momwe matenda ashuga a 2 alili ku Russia mu 2013-2014.

Dedov I., et al. Kuwonekera kwa Type 2 shuga mellitus (T2DM) mwa anthu akulu achi Russia (kuphunzira NATION). Kafukufuku wa Matenda a shuga ndi Zochita Zachipatala 2016, 115: 90-95.

International Diabetes Federation. IDF Diabetes Atlas, 7th. Brussels, Belgium: International Diabetes Federation, 2015. http://www.diabetesatlas.org.

Omelyanovsky V.V., Shestakova M.V., Avksentieva M.V., Ignatieva V.I. Zochitika zachuma za matenda ashuga machitidwe apanyumba. Tekinoloje Yachipatala: Kuunika ndi Kusankha, 2015, No. 4 (22): 43-60.

Chifukwa chiyani tikufunika majakisoni?

Matenda a shuga a Mtundu Wachiwiri amadziwika chifukwa cha kuchepa kwa kapamba komanso kuchepa kwa ntchito ya maselo a beta, omwe ali ndi udindo wopanga insulin.

Kuchita izi sikungakhudze magazi a glucose. Izi zitha kumveka chifukwa cha glycated hemoglobin, yomwe imawonetsa kuchuluka kwa shuga m'miyezi 3 yapitayi.

Pafupifupi onse odwala matenda ashuga ayenera kusamala ndi nthawi zonse chizindikiritso chake. Ngati ichulukitsa malire a zomwe zili munthawiyo (motsutsana ndi chithandizo cha mapiritsi a nthawi yayitali), ndiye njira yofunika kwambiri yosinthira kukonzekera insulin.

Pafupifupi 40 peresenti ya odwala matenda ashuga a 2 amafunikira jakisoni wa insulin.

Achibale athu omwe ali ndi matenda a shuga, pitani jakisoni zaka 12 mpaka 15 atatha matendawa. Izi zimachitika pakuwonjezeka kwa shuga komanso kuchepa kwa hemoglobin ya glycated. Komanso kuchuluka kwa odwalawa kumawonjezera matendawa.

Madokotala amafotokozera njirayi mwakulephera kukwaniritsa miyezo yapadziko lonse lapansi, ngakhale kuli kwina kwamakono kwamakono. Chimodzi mwazifukwa zazikulu izi ndi kuwopa odwala matenda ashuga a jekeseni a moyo.

Ngati wodwala yemwe ali ndi matenda osokoneza bongo sakudziwa kuti insulin ndiyabwino, akukana kusintha jakisoni kapena kusiya, ndiye kuti amakhala ndi shuga wambiri. Mkhalidwe wotere ungayambitse kukula kwa zovuta pa thanzi ndi moyo wa munthu wodwala matenda ashuga.

Ma hormone osankhidwa bwino amathandizira kuti wodwalayo akhale ndi moyo wathunthu. Chifukwa cha zida zamakono zapamwamba zomwe zingagwiritsidwenso ntchito, zidatha kuchepetsa kusasangalala komanso kupweteka kuchokera ku jakisoni.

Kulakwitsa kwa Matenda A shuga

Sikuti mankhwala a insulin nthawi zonse amalimbikitsidwa ngati mutapanda kusunga insulin yanu. Chifukwa china chingakhale izi:

• chibayo
• chimfine
• Matenda ena akuluakulu
• kulephera kugwiritsa ntchito mankhwala pamapiritsi (ndimomwe thupi limagwirira chakudya, mavuto a chiwindi ndi impso).

Kusunthira jakisoni kutha kuchitika ngati wodwala matenda ashuga akufuna kukhala moyo wabwino kapena, osatha kutsatira njira yokhazikika komanso yotsika ya carb yotsika.

Jekeseni sangathe mwanjira iliyonse yazaumoyo. Mavuto aliwonse omwe akanakhalapo pakubwera kwa jakisoni amathanso kungoona ngati mwangozi komanso mwangozi. Komabe, musataye nthawi yomwe pali insulin yambiri.

Chomwe chimapangitsa izi siziri insulini, koma kukhalapo nthawi yayitali ndimagazi osavomerezeka a shuga. Ayi, molingana ndi ziwerengero zamayiko osiyanasiyana, mukasinthana ndi jakisoni, nthawi yayitali yomwe munthu amakhala ndi moyo ndi kuchuluka kwake.

Ndi kuchepa kwa kuchuluka kwa hemoglobin wa glycated ndi 1 peresenti, mwayi wa zovuta zotsatirazi zimachepa:

• myocardial infarction (14 peresenti),
• kudula kapena kufa (43%),
• michere yamavuto (37 peresenti).

Kutalika kapena kufupikitsa?

Kuti mupeze kubisala kwapansi, ndichizolowezi kugwiritsa ntchito insulin. Mpaka pano, pharmacology imatha kupereka mitundu iwiri ya mankhwalawa. Itha kukhala insulin ya nthawi yayitali (yomwe imagwira ntchito mpaka maola 16) ndi kuwonetsa nthawi yayitali (nthawi yayitali kuposa maola 16).

Mahomoni a gulu loyamba amaphatikizapo:

1. Gensulin N,
2. Humulin NPH,
3. Insuman Bazal,
4. Protafan HM,
5. Biosulin N.

Kukonzekera kwa gulu lachiwiri:

Levemir ndi Lantus amasiyana kwambiri ndi mankhwala ena onse chifukwa amakhala ndi nthawi yosiyanitsidwa ndi thupi la odwala matenda ashuga ndipo amawonekeratu. Insulin ya gulu loyamba ndi yoyera matope. Asanagwiritse ntchito, zomwe zimagwiritsidwa ntchito ndi iwo ziyenera kugulitsidwa mosamala pakati pa kanjedza kuti mupeze yankho lofanana ndi mitambo. Kusiyanaku kumachitika chifukwa cha njira zosiyanasiyana zopangira mankhwala.

Ma insulini ochokera pagulu loyamba (nthawi yayitali) ndiwopamwamba. Mwanjira ina, nsanja ya chisautso imatha kuyambika pakuchita kwawo.

Mankhwala ochokera ku gulu lachiwiri samadziwika ndi izi. Ndizinthu izi zomwe ziyenera kukumbukiridwa posankha mulingo woyenera wa insulin. Komabe, malamulo apadera a mahomoni onse ndi ofanana.

Kuchuluka kwa nthawi yayitali insulini iyenera kusankhidwa kuti ipangitse kuchuluka kwa shuga m'magazi pakati pa zakudya zovomerezeka. Mankhwala amaphatikizapo kusinthasintha kakang'ono pamtunda kuchokera pa 1 mpaka 1.5 mmol / L.

Ngati mlingo wa insulini udasankhidwa bwino, ndiye kuti shuga ya magazi sayenera kugwa kapena kuchuluka. Chizindikiro ichi chiyenera kuchitika kwa maola 24.

Insulin yotalikilapo iyenera kubayidwa pang'onopang'ono mpaka ntchafu kapena matako. Chifukwa chakufunika koyamwa mosavuta komanso pang'onopang'ono, jakisoni m'manja ndi m'mimba ndizoletsedwa!

Zilonda m'malo awa zimapatsa zotsatirazi. Insulin yochepa-yoika, yomwe imagwiritsidwa ntchito pamimba kapena mkono, imapereka chiwongola dzanja chokwanira panthawi yomwe imayamwa chakudya.

Momwe mungaswe usiku?

Madokotala amalimbikitsa kuti odwala matenda ashuga ayambe jekeseni wa insulin nthawi yayitali. Komanso, onetsetsani kuti mukudziwa komwe mungabayire insulin. Ngati wodwalayo sakudziwa momwe angachitire izi, ayenera kumwedwa mosiyanasiyana maola atatu aliwonse:

Ngati nthawi iliyonse wodwala yemwe ali ndi matenda ashuga akadumphadumpha zizindikiritso za shuga (utachepa kapena kuwonjezeka), ndiye pamenepa, mlingo womwe ukugwiritsidwa ntchito uyenera kusintha.

Muzochitika zoterezi, ziyenera kukumbukiridwa kuti kuwonjezeka kwa glucose sikuti nthawi zonse kumachitika chifukwa cha kuchepa kwa insulin. Nthawi zina izi zimatha kukhala umboni wa latent hypoglycemia, yomwe yamveka ndi kuwonjezeka kwa glucose.

Kuti mumvetsetse chifukwa cha kuchuluka kwa shuga usiku, muyenera kuganizira bwino nthawi yonseyo. Poterepa, pakufunika kuwunika kuchuluka kwa glucose kuyambira 00.00 mpaka 03.00.

Ngati pakhala kuchepa mkati mwake munthawiyi, ndiye kuti pali chifukwa chotchedwa "pro-bending" chobisika. Ngati ndi choncho, ndiye kuti mlingo wa insulin wa nocturnal uyenera kuchepetsedwa.

Aliyense endocrinologist anganene kuti chakudya chimakhudza kwambiri kuwunika kwa insulin mthupi la wodwala matenda ashuga. Kuyerekeza kolondola kwambiri kwa kuchuluka kwa insulin ya basal kumatheka pokhapokha ngati palibe shuga m'magazi omwe amabwera ndi chakudya, komanso insulini yokhala ndi nthawi yayitali.

Pachifukwa ichi, musanayanize insulini yanu usiku, ndikofunikira kudumpha chakudya chanu chamadzulo kapena kudya chakudya chamadzulo kwambiri kuposa masiku onse.

Ndikwabwino kusagwiritsira ntchito insulin yayifupi kuti mupewe chithunzi chowoneka ngati cha thupi.

Kuti mudziyang'anire, ndikofunika kusiya kumwa mapuloteni ndi mafuta nthawi yamadzulo komanso musanayang'ane shuga.Ndikwabwino kupatsa chidwi ndi zinthu zamafuta.

Izi ndichifukwa choti mapuloteni ndi mafuta zimatengedwa ndi thupi pang'onopang'ono ndipo zimatha kuwonjezera kwambiri misempha ya shuga usiku. Mkhalidwewo, umakhala cholepheretsa kupeza zotsatira zoyenera za insulin ya usiku.

Zambiri

Insulin imagwira ntchito yofunika kwambiri m'thupi. Tili othokoza kuti maselo ndi minyewa ya ziwalo zamkati zimalandira mphamvu, chifukwa chomwe zimatha kugwira bwino ntchito ndikugwira ntchito yawo. Zikondwererozi zimaphatikizidwanso pakupanga insulin. Ndipo ndikukula kwa matenda aliwonse omwe amachititsa kuti maselo ake awonongeke, amayamba chifukwa chakuchepa kwa kapangidwe ka timadzi tambiri timeneti. Zotsatira zake, shuga yemwe amalowa mthupi mwachindunji ndi chakudya sakhala m'magazi ndipo amakhala m'magazi momwe amapangira michere. Ndipo chimayamba matenda a shuga.

Koma ndi zamitundu iwiri - yoyamba ndi yachiwiri. Ndipo ngati ndi matenda a shuga 1 pakakhala kuperewera kwina kapena kokwanira, ndiye kuti ndi matenda amtundu wa 2, vuto losiyanako pang'ono limachitika mthupi. Zikondazo zimapitilizabe kupanga insulini, koma maselo amthupi amasiya kuzimva, chifukwa amasiya kuyamwa mphamvu zonse. Potengera maziko awa, shuga samatha mpaka kumapeto komanso amakhazikika m'magazi.

Ndipo ngati mu kugwiritsa ntchito mankhwala a DM1 pogwiritsa ntchito insulin yopanga, mu DM2, kukhalabe ndi shuga wokwanira m'magazi, ndikokwanira kungotsatira njira yochiritsira, yomwe cholinga chake ndikuchepetsa kuchuluka kwa kudya tsiku ndi tsiku kwa chakudya chambiri.

Koma nthawi zina, ngakhale ndi matenda a shuga a mtundu wachiwiri, kutsatira zakudya sikumabweretsa zotsatira zabwino, chifukwa pancreas "imatopa" komanso amasiya kutulutsa timadzi tambiri tambiri. Pankhaniyi, kukonzekera kwa insulin kumagwiritsidwanso ntchito.

Amapezeka m'mitundu iwiri - mapiritsi ndi mayankho a intradermal management (jekeseni). Ndipo polankhula za zomwe zili bwino, insulini kapena mapiritsi, ziyenera kudziwidwa kuti majekeseni ali ndi chiwonetsero chachikulu kwambiri mthupi, chifukwa zomwe zimagwira zimathandizira kulowa mu kayendedwe kazinthu ndikuyamba kuchita. Ndipo mapiritsi a insulin amayambira kulowa m'mimba, pambuyo pake amapezeka kuti amapanga timitsempha ndipo kenako amalowa m'magazi.

Kugwiritsira ntchito kukonzekera kwa insulin kuyenera kuchitika pokhapokha atakambilana ndi katswiri

Koma izi sizitanthauza kuti insulini m'mapiritsi ilibe ntchito zochepa. Zimathandizanso kuchepetsa magazi a m'magazi komanso zimathandizira kukonza zomwe zimachitika wodwalayo. Komabe, chifukwa chochepa pang'onopang'ono, sioyenera kugwiritsidwa ntchito mwadzidzidzi, mwachitsanzo, poyambika kwa hyperglycemic coma.

Mwachidule kuchita insulin

Insulin Aspart ndi dzina lake lazamalonda

Insulin yochepa-yankho ndi yankho la crystalline zinc-insulin. Chowonjezera chawo ndichakuti amachita mthupi la munthu mwachangu kwambiri kuposa mitundu ina ya kukonzekera kwa insulin. Koma nthawi yomweyo, nthawi yawo yochita umatha mwachangu momwe zimayambira.

Mankhwalawa amalowetsedwa subcutaneous theka la ola musanadye njira ziwiri - intracutaneous kapena intramuscular. Kuchuluka kwa kugwiritsidwa ntchito kwawo kumatheka pambuyo pa maola 2-3 mutatha kutsata. Monga lamulo, mankhwala osokoneza bongo omwe amagwiritsidwa ntchito posachedwa amagwiritsidwa ntchito limodzi ndi mitundu ina ya insulin.

Insulin Yapakatikati

Mankhwalawa amasungunuka pang'ono pang'onopang'ono m'matumbo amkati ndipo amatengeka ndi kayendedwe kazinthu, chifukwa chomwe zimakhala ndi mphamvu kwambiri kuposa ma insulin omwe amangokhala osachita kanthu. Nthawi zambiri pochita zamankhwala, insulin NPH kapena tepi ya insulin imagwiritsidwa ntchito. Yoyamba ndi yankho la makristasi a zinc-insulin ndi protamine, ndipo chachiwiri ndi chosakanikirana chomwe chimakhala ndi kristalo ndi amorphous zinc-insulin.

Limagwirira zake zochita insulin

Insulini yapakatikati ndiyachinyama ndi anthu. Ali ndi ma pharmacokinetics osiyanasiyana. Kusiyana pakati pawo ndikuti insulin yakuchokera kwa anthu imakhala ndi hydrophobicity yayikulu kwambiri ndipo imagwirizana bwino ndi protamine ndi zinc.

Pofuna kupewa zoyipa zomwe zimagwiritsidwa ntchito ndi insulin ya nthawi yayitali, iyenera kugwiritsidwa ntchito mosamalitsa malinga ndi chiwembu - 1 kapena 2 kawiri pa tsiku. Ndipo monga tanenera pamwambapa, mankhwalawa nthawi zambiri amaphatikizidwa ndi ma insulin achidule. Izi ndichifukwa choti kuphatikiza kwawo kumapangitsa kuti mapuloteni azisakanikirana bwino ndi zinc, chifukwa chomwe kunyowa kwa insulin yocheperako kumachepetsedwa kwambiri.

Ndalamazi zimatha kusakanikirana pawokha, koma ndikofunikira kuti muzitsatira. Komanso mumasitolo ogulitsa mumatha kugula zinthu zosakanikirana zomwe ndizosavuta kugwiritsa ntchito.

Kuchita insulini kwa nthawi yayitali

Gulu la mankhwala omwe ali ndi mankhwala ali ndi kuyamwa pang'ono pang'onopang'ono m'magazi, motero amachitapo kanthu kwa nthawi yayitali. Izi amachititsa kuti magazi azikhala ndi shuga tsiku lililonse. Zimayambitsidwa nthawi 1-2 patsiku, mlingo umasankhidwa payekhapayekha. Zitha kuphatikizidwa ndi insulin zazifupi komanso zapakati.

Njira zogwiritsira ntchito

Mtundu wa insulini yotani ndi kuchuluka kwake, ndi dokotala yekhayo amene amasankha, potengera mawonekedwe a wodwalayo, kuchuluka kwa kuchuluka kwa matenda ndi kupezeka kwa zovuta ndi matenda ena. Kuti mudziwe kuchuluka kwake kwa insulin, ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magazi pambuyo pa kayendetsedwe kake.

Malo abwino kwambiri a insulin ndi khola lam'madzi pamimba.

Ponena za mahomoni omwe amayenera kupangidwa ndi kapamba, kuchuluka kwake kuyenera kukhala pafupifupi magawo 30 mpaka 40 patsiku. Zomwezo zimafunikira kwa odwala matenda ashuga. Ngati ali ndi vuto losakwanira pancreatic, ndiye kuti mlingo wa insulini ungafike pamagawo 30-50 patsiku. Nthawi yomweyo, 2/3 yake iyenera kugwiritsidwa ntchito m'mawa, ndi nthawi yonse yamadzulo, chakudya chisanachitike.

Zofunika! Ngati pali kusintha kuchokera ku nyama kupita ku insulin yaumunthu, mlingo wa tsiku ndi tsiku wa mankhwalawa uyenera kuchepetsedwa, chifukwa insulin ya munthu imatengedwa ndi thupi bwino kwambiri kuposa nyama.

Malangizo abwino kwambiri omwera mankhwalawa amadziwika kuti amaphatikiza insulin yochepa komanso yapakati. Mwachilengedwe, njira yogwiritsira ntchito mankhwalawa imadaliranso izi. Nthawi zambiri pamachitidwe otere, njira zotsatirazi zimagwiritsidwa ntchito:

• kugwiritsa ntchito nthawi imodzimodziyo insulini yochepa komanso yaying'ono pamimba yopanda kanthu m'mawa asanadye chakudya cham'mawa, ndipo madzulo kumangokhala mankhwala osakhalitsa (musanadye chakudya chamadzulo) amawayika ndikatha maola ochepa - ochita masewera olimbitsa thupi,
• Mankhwala okhala ndi kanthu kwakanthawi amagwiritsidwa ntchito tsiku lonse (mpaka kanayi pa tsiku), ndipo asanagone, jakisoni wa mankhwala a nthawi yayitali kapena yayifupi amatumizidwa,
• pa 5-6 a.m. insulin ya sing'anga kapena nthawi yayitali imayendetsedwa, ndipo musanadye chakudya cham'mawa komanso chakudya chilichonse chotsatira - chochepa.

Ngati dotolo adapereka mankhwala amodzi kwa wodwala, ndiye kuti ayenera kugwiritsidwa ntchito mosamalitsa. Chifukwa, mwachitsanzo, insulin yochepa imayikidwa katatu patsiku masana (omaliza asanagone), pakati - kawiri pa tsiku.

Zotsatira zoyipa

Mankhwala osankhidwa moyenera ndi mlingo wake pafupifupi sizipangitsa kukhalapo kwa mavuto. Komabe, pali zochitika zina pamene insulin yokha siyili yoyenera kwa munthu, ndipo pamenepa mavuto ena angabuke.

Kupezeka kwa zotsatira zoyipa mukamagwiritsa ntchito insulin nthawi zambiri kumayenderana ndi kupezeka kwa mankhwala osokoneza bongo, kosayenera pakukonzekera kapena kusungidwa kwa mankhwalawa

Nthawi zambiri, anthu amasintha okha pawokha, ndikuwonjezera kapena kuchepetsa kuchuluka kwa insulini, zomwe zimapangitsa kuti ziwonetsero zomwe sizingachitike. Kuchulukitsa kapena kutsika kwa mankhwalawa kumadzetsa kusinthasintha kwa shuga m'magazi mbali imodzi kapena imodzi, mwakutero kumayambitsa kukula kwa hypoglycemic kapena hyperglycemic coma, yomwe imatha kubweretsa mwadzidzidzi.

Vuto lina lomwe odwala matenda ashuga nthawi zambiri amakumana nalo ndi zovuta zomwe zimachitika, zomwe zimachitika kawirikawiri chifukwa cha insulini yoyambira nyama. Zizindikiro zawo zoyambirira ndizowoneka ngati kuyabwa ndi kuwotcha pamalo a jekeseni, komanso khungu la khungu ndi kutupa kwawo. Zikakhala kuti zizindikiro ngati izi zikuwoneka, muyenera kufunsa chithandizo kuchokera kwa dokotala ndikusintha kuti mupeze insulin kuchokera kwa anthu, koma nthawi yomweyo muchepetseni.

Atrophy ya adipose minofu ndi vuto lofanananso kwa odwala matenda ashuga ndi kugwiritsa ntchito insulin nthawi yayitali. Izi zimachitika chifukwa chakuwongolera pafupipafupi kwa insulin pamalo amodzi. Izi sizimayambitsa mavuto ambiri kuumoyo, koma malo omwe jakisoni amayenera kusinthidwa, popeza mulingo wawo wolowetsa umakhala wolakwika.

Pogwiritsa ntchito insulin kwa nthawi yayitali, mankhwala osokoneza bongo amathanso kuchitika, omwe amawonetsedwa ndi kufooka kwa mutu, kupweteka mutu, kutsika kwa magazi, ndi zina zambiri. Pankhani ya mankhwala osokoneza bongo, ndikofunikira kufunsa dokotala nthawi yomweyo.

Mwachidule

Pansipa tikambirana mndandanda wa mankhwala omwe amapezeka ndi insulin omwe amagwiritsidwa ntchito nthawi zambiri pochiza matenda a shuga. Amaperekedwa pazidziwitso zokhazokha, simungathe kuzigwiritsa ntchito popanda chidziwitso cha dokotala mulimonse. Kuti ndalamazo zigwire bwino ntchito, ziyenera kusankhidwa mokhazikika!

Yabwino kwambiri yochezera pang'ono insulin. Muli insulin yaumunthu. Mosiyana ndi mankhwala ena onse, imayamba kuchita zinthu mwachangu kwambiri. Pambuyo pakugwiritsidwa ntchito, kuchepa kwa shuga m'magazi kumawonedwa pambuyo pa mphindi 15 ndipo kumakhalabe m'malo ena owonekera kwa maola atatu.

Humalog mu mawonekedwe a cholembera

Zizindikiro zazikulu pakugwiritsira ntchito mankhwalawa ndi izi:

• shuga wodalira matenda a shuga
• Matupi awo sagwirizana ndi insulin ina.
• hyperglycemia
• kukana kugwiritsa ntchito mankhwala ochepetsa shuga,
• shuga wodalira insulin asanafike opaleshoni.

Mlingo wa mankhwalawa amasankhidwa payekha. Kumayambiriro kwake kumatha kuchitika pang'onopang'ono komanso m'njira zamitsempha. Komabe, kupewa mavuto kunyumba, tikulimbikitsidwa kupatsana mankhwala pokhapokha musanadye.

Mankhwala osokoneza bongo amakono, kuphatikiza Humalog, ali ndi zotsatira zoyipa. Ndipo pankhaniyi, mwa odwala ndi momwe amagwiritsidwira, mankhwalawa nthawi zambiri amapezeka, kuchepa kwa masomphenya, matupi ndi milomo. Kuti mankhwala azigwira ntchito pakapita nthawi, ayenera kusungidwa bwino. Ndipo izi ziyenera kuchitidwa mufiriji, koma siziyenera kuloledwa kuziziritsa, chifukwa pamenepa malonda amataya katundu wake wochiritsa.

Insulin Lizpro ndi dzina lake lazamalonda
Matenda a shuga

Insuman Rapid

Mankhwala enanso okhudzana ndi ma insulin osankha mwachidule kutengera timadzi ta munthu. Mphamvu ya mankhwalawa imafika pachimake patatha mphindi 30 kuchokera pakukonzekera ndipo imapereka chithandizo chokwanira kwa thupi kwa maola 7.

Insuman Rapid ya subcutaneous makonzedwe

Chochita chimagwiritsidwa ntchito mphindi 20 musanadye chilichonse. Pankhaniyi, tsamba la jakisoni limasintha nthawi iliyonse. Simungapereke jakisoni m'malo awiri. Ndikofunikira kuti musinthe nthawi zonse. Mwachitsanzo, nthawi yoyamba imachitika m'chigawo chamapewa, chachiwiri m'mimba, chachitatu pamphaka, etc. Izi zimapewe kuwonongeka kwa minofu ya adipose, yomwe wothandizirayo amakwiya.

Biosulin N

Mankhwala osokoneza bongo omwe amalimbikitsa chinsinsi cha kapamba. Ili ndi mahomoni ofanana ndi anthu, omwe amalekeredwa mosavuta ndi odwala ambiri ndipo samasangalatsa kwambiri mawonekedwe. Zochita za mankhwalawa zimachitika ola limodzi pambuyo pakukonzekera ndikufika pachimake patatha maola 4-5 jekeseni. Imakhalabe yothandiza kwa maola 18-20.

Zingachitike kuti munthu atalowetsa mankhwalawa ndi mankhwala ofanana, ndiye kuti akhoza kudwala hypoglycemia. Zinthu monga kupsinjika kwambiri kapena kudya zakudya zodumphadwala kumatha kuyambitsa kuwonekera kwake atagwiritsidwa ntchito ndi Biosulin N. Chifukwa chake, ndikofunikira kwambiri poigwiritsa ntchito kuyeza miyezo ya shuga ya magazi nthawi zonse.

Gensulin N

Zimatanthauzanso ma insulin apakati omwe amawonjezera kupanga kwa ma pancreatic. Mankhwalawa amaperekedwa mosavuta. Kugwiranso ntchito kwake kumapezekanso ola limodzi pambuyo pa kukhazikitsa ndipo kumatenga maola 18-20. Nthawi zambiri zimayambitsa kupezeka kwa zotsatira zoyipa ndipo zimatha kuphatikizidwa mosavuta ndi ma insulin omwe amakhala nthawi yayitali kapena osakhalitsa.

Zosiyanasiyana zamankhwala Gensulin