Ethamsylate (Etamsylate)
Mankhwalawa amayambitsa maphunziro thromboplastin ndimucopolysaccharidespotero kuwonetsera ntchito zazikuluzikulu.
Limasinthasintha kuchuluka kwa magazi, limawonjezera kukhazikika ndi kutanuka kwa makoma capillariesbwino njira kuyesa ngakhale muzombo zazing'ono komanso capillaries.
Ndizofunikira kudziwa kuti mankhwalawa samakhudza prothrombin index ndipo samathandizira maphunziro kuundana kwa magazi. Ngati wothandizirayo amalandiridwa kudzera m'mitsempha, ndiye kuti mavutowo amachitika pakangodutsa mphindi 10, jekeseni atatha, mpaka maola 6 mpaka asanu ndi atatu.
Zizindikiro zogwiritsidwa ntchito
Kodi mapiritsiwa ndi otani?
Mapiritsi a Ethamsilate amalembedwa:
- at magazi ochokera kosiyanasiyana
- at magazi a m'mimba,
- ndi kusamba,
- nthawi ya opaleshoni,
- mu mano, ophthalmology, urology, opaleshoni ndi matenda azamama,
- ndi kuvulala komanso magazi akutuluka magazi,
- polymenorea,
- matenda ashugaangiopathy,
- hemorrhagic diathesis.
Nthawi zambiri, mankhwalawa amapatsidwa mankhwala olemetsa kwa nthawi yayitali, kuti achepetse kuchepa kwa magazi ndi kupewa kupezeka kuchepa magazi.
Malangizo a Ethamsylate (Njira ndi Mlingo)
Mlingo, njira yothandizira ndi nthawi yayitali ya mankhwala iyenera kutsimikiziridwa ndi dokotala.
Malinga ndi malangizo a Ethamsylate mapiritsi, mankhwalawa amathandizidwa pakamwa pa 0,25-0,5 g (piritsi limodzi kapena awiri), logawidwa mu 3 kapena 4 waukulu. Kwa ana, mlingo wa tsiku ndi tsiku ndi 10-15 mg wa pa kilogalamu ya kulemera kwake, wogawidwa mu 3 Mlingo.
Sodium Ethamyl yankho la jakisoni imagwiritsidwa ntchito ngati majekesheni (kudzera m'mitsempha, kudzera m'mitsempha) kubwezera kapena kopanda, kutengera umboni.
Mlingo wa tsiku ndi tsiku ndi 0,125-0.25 magalamu (a ntchito 3-4), mlingo umodzi wambiri ndi 0.75 g (kholo - mpaka 0.375 g). Kugwiritsa ntchito kwakunja. Swab yomwe inanyowa pokonzekera imagwiritsidwa ntchito pachilonda.
Chidachi chimagwiritsidwanso ntchito ngati Chowona Zanyama. Mlingo wa amphaka ndi 0,1 ml wa kulemera kwa nyama, jakisoni amaperekedwa kawiri patsiku.
Zotsatira za pharmacological
Ethamsylate ndi njira yoteteza ndi kuletsa magazi. Zimakhudza gawo loyamba la limagwirira a hemostasis (kulumikizana pakati pa endothelium ndi mapulateleti). Ethamsylate imawonjezera kuphatikiza kwa kupatsidwa zinthu za m'magazi, imachepetsa kukana kwa capillary, potero imachepetsa mphamvu zake, ndipo imalepheretsa prostaglandin biosynthesis, yomwe imayambitsa kusagwirizana kwa maselo, vasodilation komanso kuchuluka kwa capillary permeability. Zotsatira zake, nthawi yakutuluka magazi imachepetsedwa kwambiri, kuchepa kwa magazi kumachepetsedwa.
Pharmacokinetics
Pambuyo pakukhazikika kwa mankhwalawa, mankhwalawa amawonongeka pambuyo pa mphindi 5 mpaka 15, zomwe zimachitika mkati mwa ola limodzi. Mankhwala amagwira ntchito kwa maola 4-6, pambuyo pake zotsatira zimatha pang'ono pang'ono. Pambuyo pokonzekera kulowetsedwa kwa etamsylate muyezo wa 500 mg, kuchuluka kwambiri m'madzi am'magazi kumachitika pambuyo pa mphindi 10 ndipo ndi 50 μg / ml.
Pafupifupi 72% ya mlingo wothandizidwa umachotsedwa mu maola 24 oyamba ndi mkodzo osasinthika. Hafu ya moyo wa etamsylate wa madzi a m'magazi ndi pafupifupi maola awiri. Ethamsylate amadutsa chotchinga ndipo amachotseredwa mkaka wa m'mawere.
Contraindication
Hypersensitivity kuti etamsylate kapena gawo lina lililonse la mankhwala, hypersensitivity kuti sodium sulfite. Mphumu ya bronchial, porphyria yacute, kuchuluka kwa magazi, kukha magazi chifukwa cha anticoagulant, hemoblastosis (lymphatic ndi myeloid leukemia, osteosarcoma) mwa ana.
Kuchiza kumayamba pokhapokha kupatula mawonekedwe a uterine fibrotic.
Kutulutsa mawonekedwe ndi kapangidwe kake
Amapangidwa monga njira yotsimikizika, yopanda utoto wa jakisoni ndi biconvex, mapiritsi oyera oyera ozungulira. Njira yothetsera vhesi imapezeka mu mamililita awiri a galasi pamakatoni. Mapiritsi amagulitsidwa m'matumba omwe amaikidwa m'mabhokisi a makatoni.
Mapiritsi | 1 tabu. |
Etamsylate | 250 ml |
Omwe amathandizira: polyvinylpyrrolidone K25, wowuma chimanga, magnesium stearate ndi lactose. |
Njira Zothetsera | 1 ml |
Etamsylate | 125 mg |
250 mg | |
Omwe amathandizira: sodium bicarbonate, sodium metabisulfite ndi madzi a jakisoni. |
Mlingo ndi makonzedwe
Pamaso pa opaleshoni, zomwe zili mu ampoules za 1-2 zimaperekedwa kudzera m'mitsempha kapena intramuscularly. Pa opaleshoni, zomwe zili ndi ma ampoules awiri a 1-2 zimaperekedwa kudzera m'mitsempha, kuyamwa kwa mankhwalawa kungathe kubwerezedwa. Pambuyo pakuchita opaleshoni, zomwe zili mumphindi za 1-2 zimaperekedwa pambuyo pa maola 6 aliwonse mpaka chiwopsezo chotaya magazi chikazimiririka.
Mu neonatology, Ethamsylate imayendetsedwa kudzera mu mnofu kapena mu mtsempha wa 12.5 mg / kg kulemera kwa thupi (0.1 ml = 12.5 mg). Kuchiza kuyenera kuyamba pakadutsa mawola awiri pambuyo pobadwa. Mankhwala kutumikiridwa aliyense b kwa maola 4 kwa okwanira mlingo wa 200 mg / kg.
Ethamsylate imatha kupakidwa pamwamba (khungu kumezanitsa, kupopera mano) pogwiritsa ntchito nsalu yosalala yothira mankhwala.
Zotsatira zoyipa
Kuchokera wamanjenje: kawirikawiri - kupweteka mutu, chizungulire, kugwedezeka, paresthesia yam'munsi.
Kuchokera pamtima dongosolo: kawirikawiri - thromboembolism, ochepa hypotension.
Kuchokera pamimba yokhudza kugaya chakudya: nseru, kusanza, kupweteka kwa epigastric, kutsekula m'mimba.
Kuchokera ku chitetezo chamthupi: kawirikawiri - thupi siligwirizana, malungo, zotupa za pakhungu, kukhumudwa kwa anaphylactic, nkhani ya angioedema yafotokozedwa. Kuchokera pakupuma dongosolo: bronchospasm.
Kuchokera endocrine dongosolo: kawirikawiri - pachimake porphyria.
Kuchokera ku minculoskeletal system: kawirikawiri - kupweteka kumbuyo.
Pa khungu: kuyabwa, urticaria.
Zina: kuchepa kwa minofu perfusion, yomwe imadziyimitsa payokha patapita kanthawi.
Zotsatira zake zonse ndizofatsa komanso zosakhalitsa.
Ana omwe amathandizidwa ndi etamsylate kuti ateteze magazi mu pachimake lymphatic ndi myeloid leukemia amatha kukhala ndi leukopenia woopsa.
Kuchita ndi mankhwala ena
Ngati Ethamsylate asakanizidwa ndi saline, iyenera kugwiritsidwa ntchito nthawi yomweyo.
Chikuonetseratu pamaso makonzedwe a reopoliglycin amaletsa odana osakanikirana zotsatira za chomaliza; makonzedwe pambuyo reopoliglyukin alibe he hetatic kwenikweni. Pulogalamu yovomerezeka ndi aminocaproic acid, vicasol.
Zolemba ntchito
Gwiritsani ntchito mosamala odwala omwe adalemba kale thrombosis kapena thromboembolism, komanso zotupa za m'mimba zomwe zimayambitsidwa ndi anticoagulant agents.
Ndi zovuta za hemorrhagic zogwirizana ndi mankhwala osokoneza bongo a anticoagulants, ndikofunikira kugwiritsa ntchito mitundu yeniyeni.
Mankhwalawa sagwira ntchito ndi kuchuluka kwa magazi.
Musanayambe chithandizo, zifukwa zina zoyipa magazi ziyenera kutchulidwa.
Etamsylate chithandizo cha odwala omwe ali ndi vuto la magazi pamagulu a magazi amayenera kuthandizidwa ndi kuyambitsa mankhwala omwe amachotsa kufooka kapena chilema cha zinthu m'magazi oyambitsidwa ndi magazi.
Ndi koletsedwa kugwiritsa ntchito mankhwalawa ngati kusintha kwa mtundu wa jakisoni.
Kutha kusinthitsa kuchuluka kwa zochita mukamayendetsa kapena kugwiritsa ntchito njira zina.
Pa chithandizo ndi Etamsylat, muyenera kusamala mukamayendetsa magalimoto kapena pogwiritsa ntchito njira zina, chifukwa chizungulire nchotheka.
Clinical Pharmacology
Imasinthasintha kuchuluka kwa capillary mu pathological process, kusintha microcirculation, kumawonjezera kuphatikiza kwa mapulateleti, ndipo kumakhala ndi hemostatic kwambiri. Ndi pa / m'mawu oyamba, zotsatira za heestatic zimayamba pambuyo pa mphindi 5 mpaka 15, mphamvu yayikulu - mutatha maola 1-2, zotsatira zimatha maola 4-6 kapena kupitilira. Ndi mawu oyambitsa / m, zotsatira zake zimachitika pang'onopang'ono.
Malangizo a Ethamsylate (jakisoni mapiritsi), mulingo
Mapiritsi amatengedwa pakamwa ndi madzi.
Mlingo umodzi wokhazikika wa akulu, malinga ndi malangizo ogwiritsira ntchito mapiritsi a Etamsylate, amachokera ku 250 mpaka 500 mg, omwe ndi okwanira 750 mg. Mlingo weniweni umatsimikiziridwa ndi dokotala payekhapayekha.
Ndi metro ndi menorrhagia, 250 mg imakhazikitsidwa maola 6 aliwonse masiku 5-10, ndiye 250 mg 2 kawiri pa tsiku kutaya magazi.
Ndi hemorrhagic diathesis ndi diabetesicangiopathies, nthawi zambiri zotchulidwa 0,25-0,5 g 1-2 pa tsiku.
Ndi matumbo, magazi a m'mapapo - 500 mg kwa masiku 5-10.
Mu matenda a diabetesicangiopathies, mapiritsi 1-2 patsiku amaperekedwa pa mlingo wa miyezi iwiri.
Mwanjira ya jakisoni, Ethamsylate imapangidwira ma intramuscular, intravenous, retrobulbar, subconjunctival, makonzedwe a pakamwa.
Akuluakulu: ndi ma opaleshoni othandizira prophylactically - mu / mu kapena / m 1 ora musanachitidwe opareshoni - 0,25-0,5 g kapena mkati, mosasamala kanthu za kudya, maola atatu musanayambe opareshoni - 0.5-0.75 g Ngati ndi kotheka - 0,25-0,5 g iv pa opaleshoni ndi prophylactically - 0.5-0.75 g iv, i / m kapena 1.5-2 g mkati, wogawana masana - atagwira ntchito.
Ana: ndi ma opaleshoni othandizira prophylactically - pakamwa, 1-12 mg / kg mu 2-mgawo waukulu wa masiku 3-5. Ngati ndi kotheka, nthawi ya opareshoni - mkati /, 8-10 mg / kg.
Jakisoni wa Ethamzilate amatha kuthira timatumba topaka (swala wosabala amakwiriridwa ndikugwiritsidwa ntchito pachilondacho).
Mu ophthalmology, mankhwalawa amaperekedwa kwa subconjunctival kapena retrobulbar - pa mlingo wa 0.125 g (1 ml 12,5% yankho).
Zotsatira zoyipa
Malangizowa amachenjeza za mwayi wopanga zotsatirapo zoyipa mukamapereka Ethamsylate:
- Kulemera m'mimba
- Chizungulire
- Kutentha kwa mtima
- Kuthamanga kwa magazi
- Hyperemia wa nkhope,
- Paresthesia yam'munsi,
- Mutu.
Contraindication
Amakanizidwa kuti apereke etamsylate pazochitika zotsatirazi:
- Hypersensitivity pamagawo a mankhwala,
- Thrombosis, thromboembolism, kuchuluka magazi
- Acute mawonekedwe a porphyria,
- Hemoblastosis (lymphatic ndi myeloid leukemia, osteosarcoma) mwa ana.
- Ndi magazi pa maziko a bongo wa anticoagulants.
Ethamsylate sayenera kugwiritsidwa ntchito ngati chithandizo chokhacho ngati wodwala ali ndi zotupa chifukwa cha anticoagulants.
Mankhwala osagwirizana ndi mankhwala ena. Osasakaniza mu syringe yomweyo ndi mankhwala ena ndi zinthu.
Bongo
Palibe zambiri zomwe zaperekedwa.
Analogs Etamsilat, mtengo pama pharmacies
Ngati ndi kotheka, Ethamsylate ikhoza m'malo mwa analogue yogwira ntchito - awa ndi mankhwala:
- Dicinon
- Etamsilat Ferein,
- Ethamsylate-KV,
- Jakisoni wa Ethamsylate 12,5%.
Posankha analogi, ndikofunikira kumvetsetsa kuti malangizo ogwiritsira ntchito Etamsilat, mtengo ndi kuwunika sikugwiranso ntchito ngati mankhwala omwewo. Ndikofunikira kupeza upangiri wa dokotala komanso kuti usasinthe popanda mankhwala.
Mtengo m'mafakitoreti aku Russia: Etamzilat jakisoni 125mg / ml 2ml 10 ampoules - kuchokera ku ma ruble 108 mpaka 153, pakadali pano palibe zambiri pamtengo wamapiritsi.
Sungani pamalo amdima. Moyo wa alumali ndi zaka zitatu.
Kugulitsa muma pharmacies ndi mankhwala.
Ndemanga zitatu za "Etamsilat"
Adandiyika kuchipatala nditachitidwa opaleshoni yayikulu, zinali zoyipa kwambiri, madotolo adati ndidatsala pang'ono kupita kudziko lina, koma Etamsilat adanditulutsa. Kutulutsa kwamkati pambuyo poti mankhwalawa atatseka ndipo ndinapulumuka.
Ethamzilate adalowetsedwa ndikutulutsa magazi, ndibwino kuposa tranexam, osachepera zidandithandizira bwino.
Panthawi ina, mankhwalawa adandithandiza kuti ndisiye magazi komanso kuti ndisamakhale ndi pakati!
Malangizo ogwiritsira ntchito Ethamsylate
Etamsilat wothandizira wa hemostatic (hemostatic) amakhala ndi angioprotective, proaggregate zochita. Mankhwalawa amathandizira kuwonjezeka kwa kukula kwa mapulateleti ndi kutuluka kwawo kuchokera kumongo. Amagwiritsidwa ntchito kuyimitsa ndikuletsa magazi a capillary ndi parenchymal, hemorretic hemorrhages, mu opaleshoni, gynecology, ophthalmic, mano, urological ndi otolaryngological pochita opaleshoni.
Mphamvu ya hetaticatic ya Etamsylate imachitika chifukwa cha kupangika kwa thromboplastin pamalo omwe awonongeka ndi chotengera komanso kuchepa kwa mapangidwe a prosthipclin m'makoma a chotengera, zomwe zimayambitsa kuyimitsidwa kapena kuchepa kwa magazi. Ntchito ya antihyaluronidase ya gawo lalikulu imalepheretsa kuwonongeka kwa mucopolysaccharides a makoma a capillaries, kumawonjezera kukana kwawo ndikuchepetsa kusokonekera. Kutenga mankhwalawa alibe vasoconstrictor kwenikweni, sikuthandizira ku thrombosis.
Kupanga ndi mawonekedwe a kumasulidwa
Mankhwala Etamsylate amapezeka mitundu iwiri ya mankhwala - mapiritsi amkamwa pakamwa ndi yankho la jakisoni wamkati kapena wamkati. Mapiritsi oyera a Convex ali ndi 250 mg pazomwe zimapangidwira (sodium ethamylate) ndi zina zothandiza (sodium hydrogen phosphate dihydrate, sodium metabisulfite, povidone, wowuma wa mbatata, calcium stearate). Atadzaza matuza kwa 50 kapena 100 zidutswa.
Malangizo a Ethamsylate (njira ndi mulingo)
Amapangidwa kuti azigwiritsa ntchito pakamwa, subconjunctival, intravenous, intramuscular and retrobulbar.
- Mu / mu, mu / m kwa 1 h musanachite opaleshoni, pofuna kupewa - 0.25-0,5 g (2-4 ml ya yankho la 12,5%). Ngati mungakhale ndi vuto la kutuluka kwa magazi pambuyo - - 0.5-0.75 g (4-6 ml) patsiku.
- Ngati ndi kotheka, 0,25-0,5 g (2-5 ml) amathandizira kudzera m'mitsempha. Pazifukwa zamankhwala - 0,25-0,5 g (2-4 ml) nthawi imodzi, kenako - 0,25 g maola 6 aliwonse. Mutha kulowa / kukapumira, ndikuwonjezera njira zachilengedwe zothandizira kulowetsedwa.
- Ndi metro ndi menorrhagia, 0,25 ga amatchulidwa maola 6 aliwonse kwa masiku 5 mpaka 10, ndiye kuti 0,25 g kawiri pa tsiku munthawi yotupa.
- Ndi hemorrhagic diathesis ndi diabetesicangiopathies, nthawi zambiri zotchulidwa 0,25-0,5 g 1-2 pa tsiku.
- Mlingo wa ntchito ya subconjunctival ndi retrobulbar ndi millilita imodzi.
Mlingo ndi makonzedwe
Kutalika kwa mankhwalawa pogwiritsa ntchito Etamsilat, dongosolo ndi mawonekedwe a makonzedwe, kuchuluka kwa kamodzi ndi tsiku ndi tsiku kumatsimikiziridwa ndi kupezeka kwa dokotala malinga ndi kupezeka kwake ndi zizindikiro zake. Mlingo womwe umalimbikitsa ndi malangizo:
- Mukamamwa pakamwa: 250-500 mg katatu pa tsiku (mlingo umodzi, wowonjezera pakamwa umachulukitsidwa mpaka 750 mg ndi zisonyezo zoyenera),
- kudzera m'mitsempha kapena m'mitsempha: 125-250 mg, jakisoni 3-4 patsiku,
- ka makulidwe a makolo: mpaka 375 mg,
- muubwana: 10-15 mg / kg patsiku, jakisoni 3 patsiku, Mlingo wofanana.
Mapale a Ethamsylate
Oral makonzedwe a mankhwala amathandizidwa kuti azichiza matenda ndi kupewa magazi omwe ali ndi matenda ashuga microangiopathies ndi diathesis. Ethamzilate yolemetsa kwa nthawi yayitali komanso pochiza matenda ammbuyo imalimbikitsidwanso pakamwa. Malonda omwe angachitike:
- Metro ndi menorrhagia pa msambo ndi mankhwala osokoneza bongo uterine magazi - 0,5 g kamodzi maola 6, njira ya mankhwala - masiku 5-12. Poteteza - piritsi 1 kanayi patsiku pamagazi, komanso masiku awiri otsatira.
- Matenda a shuga angiopathy - mapiritsi 1-2 katatu patsiku, mankhwala 2-3 miyezi.
- Kupewera kwa vuto la kutuluka kwa magazi - mapiritsi a 6-8 patsiku ndi kufananiza kwa Mlingo uliwonse kwa maola 24.
Etamsylate mu ampoules
Jakisoni wa Ethamsilate amagwiritsidwa ntchito popewa kutulutsa magazi isanachitike kapena itatha opaleshoni yokhala ndi ziwonetsero zoyenera (2-4 ml intramuscularly kapena kudzera m'mitsempha, ola limodzi asanachitidwe opaleshoni). Ngati pali chiopsezo chakutuluka kwa magazi pambuyo pa mankhwalawa, 4-6 ml patsiku ndi mankhwala. Njira zomwe mungagwiritse ntchito:
- hemorrhagic diathesis - 1.5 g, jekeseni imodzi patsiku, nthawi yayitali 5 masiku,
- mu ophthalmology - 0,125 g (1 ml ya yankho) subconjunctival kapena retrobulbar,
- mu Chowona Zanyama - 0,5 ml pa kilogalamu ya kulemera kwa nyama kawiri pa tsiku.
Etamsylate pa nthawi yapakati
Pa mimba, etamsylate imayikidwa mosamala. Simalimbikitsidwa kuti mugwiritse ntchito pa trimester yoyamba. Ngati pali kuwonongeka kapena kuwonongeka pangozi pambuyo pake, imagwiritsidwa ntchito limodzi ndi Progesterone poyang'anira kuchuluka kwa magazi nthawi zonse. Kusankhidwa kwake kuyenera kuchitika ndi dokotala yemwe akutsogolera kutenga pakati, kudzipereka yekha pakubwera kumabweretsa zotsatirapo zoyipa kwa thanzi la mayi kapena mwana wosabadwayo.
Kuyanjana kwa mankhwala
Sizovomerezeka kusakaniza yankho la Ethamsylate mu syringe yomweyo ndi mankhwala ena. Mothandizanso pamodzi ndi gulu la mankhwala la dextrans, ndikamayambitsa mankhwala omwe ali ndi mulingo wa 10 mg / kg ola limodzi pamaso pa oyang'anira, kuchepa kwa antiplatelet kungatheke, makonzedwe atakhala kuti sanatchulidwe kwakukulu. Ntchito yovomerezeka yophatikizidwa ndi aminocaproic acid, sodium menadione bisulfite.
Zotsatira zoyipa ndi bongo
Njira ya mankhwalawa pogwiritsa ntchito Ethamsilate nthawi zambiri imalekeredwa bwino, malinga ndi malangizo, tsiku lililonse. Palibe milandu ya bongo yomwe imanenedwa, ndi magazi ovuta omwe amayamba chifukwa cha mankhwala opatsirana ambiri, kugwiritsa ntchito mankhwala enieniwo kukuwonetsedwa. Zotsatira zoyipa za kumwa mankhwalawa:
- kumva kusasangalala kapena kuwotcha pachifuwa,
- kutentha kwa mtima
- kupweteka m'mimba
- kuchepa magazi
- kutsika kwa kupanikizika kwa intracranial,
- nkhope
- mutu ndi chizungulire,
- ochepa matenda oopsa
- kutsitsa magazi a systolic,
- paresthesia a khungu (dzanzi, kumva kugunda) kwa m'munsi malekezero.
Migwirizano yogulitsa ndikusunga
Ethamsylate imagawidwa muma pharmacies monga adanenera dokotala. Sungani zinthuzo kuti zisafike kwa ana, pamalo amdima, pa kutentha osaposa 25 ° C. Moyo wa alumali - zaka ziwiri kuyambira tsiku lomwe lasonyezedwa pa phukusi.
Analogue yathunthu yokhayo ya mankhwala a Ethamsilate ndi Dicinon. Zotsatira zoyipa zimachitika kapena ngati munthu wapezeka kuti watsala ndi vuto linalake, ndiye kuti amuchotsa pamankhwala ena omwe amathandizawa:
Mtengo wa Etamzilat
Mutha kugula Etamsylat mu pharmacy kapena pazachuma zapadera pa intaneti, kukonza njira yakunyumba. Mtengo wapakati wamitundu yonse yotulutsidwa:
Mtengo wamitundu, m'm ruble
Njira yothetsera kulowetsedwa mu mnofu ndi mtsempha, ma ampoules No. 10 2 ml 12.5%
Oksana, wazaka 28. Ethamsilate ku dokotala wazachipatala amandilimbikitsanso kuti nditenge kubadwa kwachiwiri chifukwa cha kuwonjezeka kwa magazi ndi kuphwanya nthawi yayitali. Ndinkamwa mapiritsi molingana ndi chiwembu chokhazikitsidwa - mapiritsi 4 pa maola 6 aliwonse masiku asanu ndi atatu oyamba azungulira. Chilichonse chosinthika kale m'mwezi wachiwiri wolandila, maphunzirowa adapita kumapeto. Panalibe mavuto.
Anna, wazaka 42. Ndi kutaya magazi muchiberekero pambuyo pathupi, mapangidwe a jekeseni a Ethamsilate adalembedwa - jekeseni awiri patsiku kwa masiku 7. Kutulutsa magazi kuyima pambuyo pa jakisoni woyamba. Malonda ake ndi otsika mtengo, anachitapo kanthu mwachangu, kunalibe zotsatirapo zake, mkhalidwe wabwinobwino pakati pa maphunziro sanasinthe. Anakukwapula m'mitsempha, analekerera njirayo bwino.
Marina, wazaka 33. Pa nthawi yoyembekezera, adasungidwa pamasabata 18 chifukwa chowala mwamphamvu. Ethamzilate anali jekeseni kudzera masiku awiri (ampoule kawiri pa tsiku), kenaka masiku enanso angapo intramuscularly pa tsiku. Pogona ponsepo, kutuluka magazi patatha masiku atatu. Kupitilira apo, kutenga pakati sikunachitike, mwana ali ndi thanzi.
Mtengo mumafakisi
Mtengo wa Etamzilat wa phukusi limodzi ndikuchokera ku ma ruble 108.
Malongosoledwe patsamba lino ndi mtundu wosavuta wa mtundu wazovomerezeka zamankhwala. Chidziwitsocho chimaperekedwa kuti chizidziwitso chokha komanso sikuti chitsogozo chodzidzipangira nokha. Musanagwiritse ntchito mankhwalawa, muyenera kufunsa katswiri kuti mudziwe malangizo omwe amavomerezedwa ndi wopanga.