Kodi chimathandiza Siofor ndi chiyani? Malangizo, mtengo, ndemanga ndi fanizo

Siofor ndi mankhwala ochokera pagulu la Biguanide. Chofunikira chachikulu ndi metformin, yomwe yakhala ikugwiritsidwa ntchito pochiza matenda ashuga kwa zaka zambiri.

Mosiyana ndi othandizira ena odwala matenda ashuga, mankhwalawa amachepetsa kupanga shuga m'magazi a chiwindi, amalepheretsa mayamwidwe ake kuchokera kumtunda kwa m'mimba, amawonjezera kufunikira kwa minofu, komanso amachepetsa kuchepa kwa insulin mthupi.

Zotsatira zazikulu za kumwa mankhwalawa:

• kutsitsa ndikukhazikika pamlingo wa glycosylated hemoglobin ndi glucose wamagazi,
• kuchuluka kwa glucose ndimisempha,
• kuchuluka kulolera kwa shuga.

• Amachepetsa kuchepa kwambiri komanso ochepa kwambiri a lipoproteins,
• imakhala ndi antioxidant komanso zoteteza kumatenda a cell,
• amatero kulemera kwa thupi kunenepa kwambiri.

Mankhwalawa amagwiritsidwa ntchito pochiza matenda a shuga a mtundu wachiwiri.

Mitundu ya kumasulidwa kwa mankhwala

Mankhwalawa ali ndi mitundu ingapo yomasulidwa, ndipo onse amaikidwa, zomwe zimapangitsa kuti mankhwalawo akhale abwino kwambiri kumwa kunyumba.

• Siofor 500 - mapiritsi oyera, okwera, otsekemera, osindikizidwa m'matumba apadera a zidutswa khumi ndi zisanu, makatoni aliwonse okhala ndi matuza awiri kapena asanu ndi atatu,
• Siofor 850 - mapiritsi oyera, oblong, nawonso wokutira, atanyamula matumba a zidutswa khumi ndi zisanu, m'katoni kalikonse kutengera matuza awiri mpaka eyiti,
• Siofor 1000 - mapiritsi oyera okhala ndi mawonekedwe ang'ono pansi, ali ndi chipolopolo, amakhalanso ndi matuza a zidutswa khumi ndi zisanu, mu phukusi limodzi kuchokera ku matuza awiri mpaka eyiti okhala ndi mapiritsi.

Contraindication

Kufotokozera kwa mankhwala aliwonse kumaphatikiza chaputala pa contraindication. Palibe chidwi ndi gawo ili la maphunziro, pali chiopsezo chachikulu cha zovuta zamitundu mitundu.

Zotsatira zamagwiritsidwe ntchito a Siofor ngati othandizira odwala matenda ashuga:

• congenital hypersensitivity pamagawo a mankhwala,
• mtundu 1 matenda a shuga, wodalira insulin,
• pambuyo pa hyperglycemia,
• zotchulidwa ketoacids,
• mankhwalawa: kugunda kwa mtima, kugwiritsidwa ntchito kwa poizoni ndi kugunda kwa mtima.
• zosokoneza pamiyeso yamagetsi yamagetsi,
• kutopa ndi matenda a anorexia,
• kuwonongeka kwakukulu kwa thupi loposa 40%,
• kutaya magazi kwa malita oposa theka ndi theka,
• opaleshoni ya opaleshoni wamba kapena ya msana,
• matenda opatsirana a genitourinary dongosolo ndi bronchopulmonary dongosolo,
• matumbo kutsekeka kwa spastic kapena ziwalo,
• zam'mimba motility matenda,
• maldigestion ndi malabsorption,
• matenda a endocrine dongosolo: thyrotooticosis, autoimmune chithokomiro, matenda amkuwa, matenda a shuga ogwedezeka,
• febrile syndrome
• kumwa kwa nthawi yayitali ndi chitukuko cha poyizoni wa mowa,
• kusuta
• pakati pamiyala yonse itatu,
• yoyamwitsa
• gulu la zaka mpaka khumi ndi anthu azaka zopitilira 60
• zotupa zam'mimba ndi mafupa a zilonda zoyipa ndi chosaopsa.

Mlingo umatengera ngati mankhwalawo adzagwiritsidwa ntchito limodzi ndi ena othandizira odwala matenda ashuga. Mlingo woyenera kwambiri amasankhidwa ndi endocrinologist atakayezetsa kuchipatala. Mankhwalawa amatha kukhala ndi 0,5, 0,85 ndi 1 gramu ya chinthu chachikulu.

Chithandizo cha Siofor chokha

Amayamba kumwa mankhwalawa ndi 0,5 magalamu kamodzi kapena kawiri pa tsiku kapena 0,85 magalamu kamodzi patsiku. Masabata awiri pambuyo poyambira kukhazikitsa, pakalibe zotsatira zoyipa, onjezani mlingo pang'onopang'ono mpaka magalamu 1.5-2. Mukamachulukitsa pang'onopang'ono kuchuluka kwa mankhwalawo, ndiye kuti zotsatirapo zake zimayambitsa matenda ochepa.

Kuphatikiza mankhwala

Nthawi zambiri, kuphatikiza kwa siofor ndi insulin kumagwiritsidwa ntchito popanga shuga. Nthawi yomweyo, amayamba kumwa mapiritsi ndi 0,5 ga magalamu, sabata iliyonse amawonjezera ndi theka la gramu mpaka amafikira mlingo wamba wa tsiku ndi tsiku (magalamu 3-4). Chiwerengero cha jakisoni wa insulini chimatsimikiziridwa poyesa shuga m'magazi.

Malangizo ogwiritsira ntchito

Siofor, omwe malangizo ake ogwiritsira ntchito samayambitsa zovuta zinazake, amatengedwa kamodzi kapena kawiri patsiku (kutengera mlingo womwe wafotokozedwa ndi katswiri). Ndikulimbikitsidwa kumwa mapiritsi musanadye chakudya chachikulu, ndikutsuka ndi kapu yamadzi oyera. Sizovomerezeka kumwa piritsi ndi mowa, zipatso zosapsa kapena msuzi wa masamba, komanso zinthu monga mkaka, chifukwa izi sizingasokoneze mphamvu ya kuchiritsa kwa chinthucho.

Malangizo apadera

Ngati mankhwalawa adapangidwa kuti aphatikizidwe ndi sulfonylurea zotumphukira kapena insulin, amafunika kuganizira kuchuluka kwa shuga m'magazi nthawi zosiyanasiyana masana. Ndikofunikanso kuyesa mayeso a glycosylated hemoglobin.

Pambuyo kumwa mankhwalawa, tikulimbikitsidwa kuti mupeze mkodzo wambiri ndi zamanjenje pakapita miyezi isanu ndi umodzi, komanso kudziwa kuchuluka kwa kusefedwa kwa glomerular. Kuyeserera uku kumakupatsani mwayi wodziwa momwe impso zimayambira komanso momwe mankhwalawo amathandizira mu kwamikodzo.

Ngati wodwala ali ndi matenda am'mapapo, matenda a chiwindi, kapena matenda opatsirana komanso matenda a parasitic, muyenera kudziwitsa dokotala wanu za izi ndikufunsani njira zamankhwala ena.

Ngati wodwalayo akufufuzidwa ndikuyambitsa kusintha kwa radiology kapena opaleshoni, mankhwalawo amathetsedwa masiku awiri isanachitike.

Kuyamwitsa sikugwirizana ndi kumwa mankhwalawa. Ndemanga za akatswiri zimatsimikizira kuti mankhwalawa amamuchotsa mkaka wa m'mawere. Pokonzekera kutenga pakati pakatha miyezi ingapo mutatha kumwa mankhwalawa, muyenera kudziwitsa adotolo za izi ndikupanga zina.

Kugwirizana kwa mankhwala ndi mankhwala ena

Mankhwala angapo akapezeka m'thupi nthawi imodzi, izi zimatha kusintha zotsatira zake. Matenda a shuga omwe ndi ovuta kuwongolera amatsogolera pakugwiritsa ntchito othandizira angapo a hypoglycemic nthawi imodzi, zomwe zingayambitse zovuta zina.

Zotsatira zamgwirizano wa Siofor ndi mankhwala ena:

• loop, thiazide ndi potaziyamu woleketsa okodzetsa amachepetsa kuchepa kwa shuga,
• glucocorticosteroids, kulera kwa mahomoni, mankhwala osokoneza bongo a akazi ndi amuna (omwe ali ndi testosterone, estrogens) zimawononga ntchito ya hypoglycemic,
• nifedipine, nicardipine amonjezera kuyamwa kwa mankhwalawa kumtunda kwam'mimba,
• insulin ndi zinthu monga insulin, kukonzekera kwa sulfonylurea kumawonjezera mphamvu ya mankhwalawo ndipo kumatha kupweteka.
• antidepressants, angiotensin-converting enzyme inhibitors ndi maantibayotiki ena amawonjezera mphamvu ya siofor,
• Mukamamwa cimetidine, mankhwala am'mimba amisokoneza, omwe angayambitse ketoacidosis,
• kumwa mowa kumawonjezera chiopsezo cha dziko la ketoacidotic kangapo,
• Zinthu zokhala ndi ayodini wokhala ndi ayodini kuphatikizika ndi siofor zimatha kuyambitsa mavuto ambiri ndi Quincke's edema komanso chitukuko cha anaphylactic.

Zotsatira zoyipa

Siofor 500 imatha kuyambitsa mavuto ena, omwe mikhalidwe yake ndi iliyonse yamankhwala. Ambiri aiwo amawuka chifukwa cha machitidwe amomwe munthu amagwirira ntchito pazinthu zazikulu komanso zowonjezera za mankhwala ndi zolandilira thupi.

Zotsatira zoyipa kuchokera pa kutenga Siofor:

• dyspepsia paziwonetsero zonse: Zizindikiro za kutentha pamtima ndi kuwawa mkamwa, malamba,
• kutsegula kwa gag reflex, nseru,
• kudzimbidwa,
• kusokonezeka kwa mpweya m'mimba m'munsi,
• ndikuluma m'mimba,
• kumva kukhuta mutatha kudya chakudya chochepa,
• kununkhira kowawa wowopsa kwa malovu ndi kukhudza chitsulo,
• kuchepa kwambiri kwa shuga m'magazi, zomwe zimatsogolera mikhalidwe ya hypoglycemic,
• syncope ndi syncope
• migraines ndi migraine vertigo,
• ulesi, mantha,
• kuwonda
• kupsinjika kwakutali, ndikutsatira mwamtopola,
• hematopoiesis: megaloblastic anemia,
• kusintha kwa machitidwe
• kugwedezeka kwamphamvu,
• kugona kwambiri kapena kusowa tulo,
• kuyabwa pakhungu,
• kusenda khungu
• zidzolo pakhungu ndi pakhungu,
• matupi awo sagwirizana ndi: Matupi a Quincke, kuwopsa kwa anaphylactic,
• kukula kwa pachimake aimpso kulephera,
• kukula kwa matenda a chiwindi osagwira.

Mankhwala ali pagulu lamtengo wapakati. Ndondomeko yamitengo m'mizinda yosiyanasiyana yapadziko lapansi imasiyana pang'ono. Monga m'mizinda yayikulu ndi m'chigawo, mtengo umatengera mlingo womwe dokotala wakupatsani. Zosiyana pamtengo wa Siofor 500 ndi Siofor 1000 ndizofunikira kwambiri.

Mtengo wapakati m'mizinda padziko lonse lapansi:

1. Ku Moscow ndi dera la Moscow, mankhwalawa amatha kupezeka pamtengo wa 340 mpaka 850 rubles.
2. Ku St. Petersburg, mtengo wa mankhwalawa udzachokera ku ruble 350 mpaka 850.
3. M'masitolo azachipatala mumzinda wa Chelyabinsk siofor amachokera ku 265 mpaka 340 rubles.
4. Mankhwala a Novosibirsk amagulitsa mankhwalawa pamtengo wa ma ruble 215 mpaka 800.
5. Ku Lipetsk ndi dera la Lipetsk, munthu akhoza kupereka kuchokera ku 212 mpaka 840 rubles mankhwala.
6. Mankhwala mu Rostov-on-Don amawonetsa mankhwala amtengo pamtengo kuchokera pa 347 rubles mpaka 860.
7. Ku Vladivostok, mutha kugula mapiritsi awa pamtengo wa 234 mpaka 836 rubles.

Siofor, monga mankhwala aliwonse, ali ndi mawonekedwe ake. Ambiri aiwo amasiyana m'maiko opanga. Mitundu ina ya mankhwalawa imasintha pang'ono pazomwe zimapangidwa, zomwe zimapangitsa kuti azitha kulandira ndalama zambiri kwa anthu ena.

Mofanizira waukulu wa mankhwala:

1. Glucophage ndi mankhwala opangidwa ku France omwe ali ndi zosiyana zina pazinthu zothandizira za mankhwalawo. Mtengo muma pharmacies ndi 122 mpaka 322 rubles.
2. Bagomet, mosiyana ndi mankhwala ena, ali ndi zoletsa zina zakagwiritsidwe ntchito: kwa anthu azaka zopitilira makumi asanu ndi limodzi zimaperekedwa mosamala kwambiri. Gawo la mitengoyo limachokera ku ma ruble 110 mpaka 340.
3. Glycon ndi mankhwala aku Canada. Komanso, monga ma analogu ena, imakhala ndi metformin, koma imapezeka mu mawonekedwe a mapiritsi omwe amaikidwa m'mabotolo. M'mafakitare mungapeze pamtengo wokongola wa ma ruble 219.
4. Glyminfor ndi mankhwala ochokera ku kampani yopanga mankhwala ku India. Amayambitsa zovuta zina zomwe zimakhudzana ndi vuto la m'mimba ntchito. Ndemanga za mankhwalawa ndizosakanikirana. Mtengo wolimbikitsidwa muma pharmacies ndi ma ruble 200.
5. Forom Pliva - ali ndi kusintha kwakung'ono mu kapangidwe ka anthu ochulukirapo. Mtengo wotsiriza m'mafakitore ndi ma ruble 250.
6. Metfogamma ndi mankhwala achi Germany. Kugwiritsa ntchito nthawi yayitali, kumayambitsa kuchepa kwa vitamini. Kugulitsidwa ku malo ogulitsa mankhwala pamtengo wa 180 mpaka 660 rubles.
7. Metformin yayitali - mosiyana ndi metformin yokhazikika, ili ndi mphamvu yayitali. Mtengo wake umachokera ku ruble 135 mpaka 262.

Bongo

Mukamamwa mankhwalawo kuposa momwe wodwala amalimbikitsira, wodwalayo amakhala ndi lactic acidosis (kusintha kwa acid-based usawa).

Zizindikiro zazikulu za lactic acidosis:

• nseru
• kusanza
• kutsegula m'mimba
• kupweteka m'mimba
• kuchuluka kwa mpweya,
• kupweteka kwa minyewa ya spasmodic
• kumverera kwa kusowa kwa mpweya.

N`zothekanso kukula kwa hypoglycemia, kudutsa mu hypoglycemic chikomokere. Vutoli limaphatikizidwa ndi kutayika kwa chikumbumtima, kupsinjika kwa mawonekedwe am'mimba, thumbo losakhazikika, thukuta lozizira komanso kupuma kwabasi.

Thandizo loyamba la hypoglycemia ndi lactic acidosis - shuga wambiri pakamwa komanso kudzera m'mitsetse.

Mutha kugwiritsa ntchito shuga kapena uchi pang'ono. Zitatha izi, wodwalayo amayenera kupita kuchipatala chapadera, komwe akamupeza ndi hemodialysis kuti amuchotsere zinthu zomwe zimagwira mthupi.

Siofor ndi mankhwala othandiza kwambiri a hypoglycemic omwe ali ndi zabwino komanso zofunikira zingapo. Ndikofunika kukumbukira kuti, choyambirira, Siofor 500 ndi Siofor 1000 amathandizira kuchepetsa shuga wamagazi, ndipo kudalira ndemanga za omwe amawagwiritsa ntchito ngati mankhwala ochepetsa thupi sikuyenera. Chithandizo chilichonse chimayenera kufotokozedwa ndikuvomerezedwa ndi katswiri.

Kutulutsa mawonekedwe ndi kapangidwe kake

Siofor imapezeka mu mawonekedwe a mapiritsi okhala ndi mawonekedwe oyera a filimu.

Zomwe zimagwiritsidwa ntchito ndi metformin hydrochloride. Voliyumu yake pokonzekera ndi 500 mg, 850 mg kapena 1000 mg, othandizira: povidone, hypromellose, magnesium stearate, filimu ating: macrogol 6000, hypromellose, titanium dioxide.

Mankhwala

Siofor, malangizo ogwiritsira ntchito amatsimikizira izi, zimapereka kuchepa kwa shuga komanso kutsika kwa shuga m'magazi. Simalimbikitsa kubisalira kwa insulin chifukwa chake sikumabweretsa hypoglycemia.

Kuchita kwa metformin (yogwira pophika) mwina kutengera njira izi: kuchepa kwa shuga m'magazi chifukwa cha kuletsa kwa gluconeogeneis ndi glycogenolysis, kuwonjezeka kwamatenda a insulin ndipo, chifukwa chake, kusintha kwamphamvu kwa glucose m'matenda ndi kugwiritsidwa ntchito kwake, kulepheretsa kwa mayamwidwe a glucose .

Mapiritsi a Siofor a 500 mg, 850 mg kapena 1000 mg pazochita zawo pa glycogen synthetase amalimbikitsa syntracellular glycogen synthesis. Kuthekera kwamapuloteni onse amtundu wa glucose odziwika bwino kumawonjezeka.

Mosasamala kanthu za kuchuluka kwa glucose m'magazi, mankhwalawa ali ndi phindu pa metabolidi ya lipid, zomwe zimapangitsa kuchepa kwa cholesterol yonse, cholesterol yotsika kwambiri komanso triglycerides.

Mankhwala "Siofor": malangizo a momwe angagwiritsire ntchito

Malangizo ndi mlingo wa mankhwalawo, komanso nthawi yayitali ya mankhwala, amatsimikiziridwa ndi adotolo potengera kuchuluka kwa shuga m'magazi a wodwala.

Akuluakulu Ndi monotherapy, muyeso woyenera wa mankhwalawa ndi 500 mg (1/2 piritsi ya Siofor 1000 kapena 1. Siofor 500) kawiri pa tsiku kapena 850 mg (piritsi limodzi la Siofor 850) nthawi imodzi tsiku.

Patatha masiku 10-15 chiyambireni kumwa mankhwalawa, kuchuluka kwina kwa mankhwalawa (pang'onopang'ono) kumatheka malinga ndi kuchuluka kwa shuga m'magazi kwa pafupifupi tsiku lililonse mapiritsi a 3-4. 500 mg, mapiritsi 2-3. 850 mg aliyense, mapiritsi awiri Siofor 1000 mg.

Pankhaniyi, mlingo woyenera wovomerezeka ndi 3000 mg patsiku wogawidwa mu 3 Mlingo.

Kwa odwala omwe akupatsidwa mlingo waukulu wa mankhwala (2000-3000 mg patsiku), m'malo mwake mapiritsi awiri ndi otheka. 500 mg piritsi limodzi 1000 mg.

Mukasamutsa odwala ku mankhwala osokoneza bongo ndi mankhwala ena a antidiabetes, ndikofunikira kusiya kumwa kaye ndikuyamba kumwa mapiritsi a Siofora pamankhwala omwe ali pamwambawa.

Pogwiritsa ntchito mankhwalawa limodzi ndi insulin, muyezo woyambira ndi 500 mg 1-2 kawiri pa tsiku kapena 850 mg 1 nthawi patsiku. M'tsogolomu, mlingo umakulitsidwa pang'onopang'ono mpaka pafupifupi tsiku lililonse:

• 3-4 mapiritsi Siofor 500 mg
• Mapiritsi 2-3 850 mg aliyense
• 2 tabu. 1000 mg aliyense.

Chitani izi pakadutsa sabata limodzi. Mlingo wa insulin umakhazikitsidwa potengera kuchuluka kwa shuga m'magazi. Mlingo woyenera wovomerezeka ndi 3000 mg patsiku wogawidwa pawiri.

Ana azaka zapakati pa 10 mpaka 18.Mlingo woyambirira wophatikizidwa ndi insulin ndi monotherapy ndi 500 mg ndi pafupipafupi 1 nthawi patsiku kapena 850 mg 1 nthawi patsiku.

Patatha masiku 10-15 chiyambireni chithandizo, kuwonjezereka kwa mankhwalawa kumatheka malinga ndi kuchuluka kwa shuga m'magazi. Mlingo wovomerezeka wa ana ndi 2000 mg patsiku logawidwa mu Mlingo wa 2-3. Mlingo wa insulin umatsimikizika poganizira kuchuluka kwa shuga m'magazi.

Zotsatira zoyipa

Kumwa mankhwalawa kumatha kuyambitsa zotsatirazi zotsatirazi:

• zotupa pakhungu
• anemia yam'magazi,
• kusowa kwa chakudya
• kusanza, kusanza,
• kutsegula m'mimba
• chisangalalo
• kupweteka m'mimba
• kukoma kwazitsulo mkamwa
• hypoglycemia (kuphwanya njira yeniyeni),
• Ndi chithandizo chotalika, kupanga B12 hypovitaminosis (malabsorption) ndikotheka,
• munthawi zina (ndi mankhwala osokoneza bongo, pamaso pa matenda omwe kugwiritsa ntchito mankhwalawa akuphatikizidwa, ndi uchidakwa), lactic acidosis ingayambike (imafuna kusiya kwa mankhwalawa).

Mndandanda wa mankhwalawa "Siofor"

Zofananira zonse zogwira ntchito:

1. Sofamet.
2. Fomu.
3. Metospanin.
4. Metfogamma 1000.
5. NovoFormin.
6. Metfogamm 500.
7. Metphogamm 850.
8. Glyminfor.
9. Methadiene.
10. Metformin.
11. Bagomet.
12. Glucophage.
13. Glucophage Kutalika.
14. Forin Pliva.
15. Langerine.
16. Metformin hydrochloride.
17. Nova Met.
18. Glycon.
19. Glformin.

Maholide ndi mtengo

Mtengo wapakati wa Siofor ku Moscow ndi 322 rubles. Ku Kiev, mutha kugula mapiritsi (500 mg No. 60) kwa 179 hhucnias, ku Kazakhstan - kwa 1595 tenge. Ku Minsk, malo ogulitsa mankhwala amapatsa Siofor 850 No. 60 kwa 9-10 bel. ma ruble. Imapezeka ku pharmacies ndi mankhwala.

Pafupifupi Siofor 1000, 850, 500, ndemanga za madokotala ndizabwino kwambiri, koma akatswiri amatsimikizira kuti mankhwalawa amayenera kumwedwa kokha ndi odwala omwe ali ndi matenda osokoneza bongo, osakhala athanzi, otaya anthu olemera. Mankhwalawa amathandizanso kubwezeretsa shuga moyenera komanso, anthu omwe ali ndi matenda ashuga omwe amamwa mankhwalawa amachepetsa thupi.

Pa intaneti mungapezeko ndemanga zambiri za iwo omwe achepetsa thupi mothandizidwa ndi chida ichi, omwe amati mukamamwa, chidwi chanu chimachepa. Komabe, mavuto amayenera kukumbukiridwa. Simungamwe mankhwalawo popanda mankhwala a dokotala.