Ndi chiyani chabwino kutenga ndi matenda a shuga a Metformin kapena glucophage?

Matenda a shuga ndi matenda osapweteketsa a endocrine omwe amayamba chifukwa cha kusowa kwa insulin kapena kuchepa kwa chidwi cha maselo kwa icho, ndikudzipanga bwino. Nthawi zambiri, matenda ashuga amakhumudwitsa kuchuluka kwa zovuta zomwe zimachitika. Timalongosola zochepa za izo: kuchepa kwa mawonekedwe owoneka. hepatic ndi aimpso kulephera. Matenda a m'chiberekero. kapamba. matenda a mtima, mitsempha yamagazi ndi kupezeka kwa thrombosis.

Mavutowa amakula pakapita nthawi, koma ndimankhwala okwanira, matupi awo amatha kuchepetsedwa, ndipo nthawi zina amasintha. Ichi ndichifukwa chake mankhwala antidiabetic adapangidwa. Monga Metformin ndi Glucofage. Tsopano lingalirani chilichonse mwatsatanetsatane.

Metformin ndi mankhwala antidiabetes omwe ndi am'kalasi khwawa. Kuchita kwake kumatsimikiziridwa ndi kuthekera kuchepetsera kutumiza kwa ma elekitironi kwa ma cell ma mitochondria, komwe kumabweretsa kuwonjezeka kwa glucose. Chifukwa cha izi, glycogen zomwe zimakhala m'maselo a chiwindi zimachulukana, ndipo zimakhazikika m'maselo a minofu ndi matumbo.

Mankhwala amachititsa kusintha kwa chiŵerengero cha womangidwa insulin kuti amasuke, pofuna kuwonjezera chomaliza. Kuwonjezeka kwa proinsulin ya mahomoni kumawonedwanso. Mankhwalawa amathandizira kuchepetsa shuga.

Chifukwa cha kuthekera kwa mankhwalawa kukulitsa chidwi cha maselo kuti apange insulin popanda kulimbikitsa kudzipanga kwake ndi ma cell a pancreatic, kumalepheretsa chitukuko cha hyperinsulinemia, chomwe chimapangitsa kwambiri kunenepa kwambiri komanso mtima ndi zovuta za matenda ashuga.

Mukamatengedwa pafupipafupi, Metformin imathandizira kuchepetsa kulemera kwa thupi popewa kudya komanso kulimbikitsa glycolysis.

Ili ndi katundu woletsa kukula kwa kuchuluka kwa makoma amitsempha yamagazi, ndikothandiza pa mtima ndi m'mitsempha yamagazi.

Metformin imagwiritsidwa ntchito ngati gawo la chithandizo chovuta kwambiri cha matenda a shuga 1 amtundu wa insulin. Pochiza matenda a shuga a mtundu wa 2, angagwiritsidwe ntchito ngati mankhwala oyamba a antiidiabetes. Metformin imathandiza kwambiri pochiza matenda ashuga ovuta chifukwa cha kunenepa kwambiri.

Glucophage ndi mankhwala osokoneza bongo a m'gulu la Biguanides. Zochita zake zogwira ntchito zimayambitsa kutsika kwa glucose, popanda kuwonjezera mahomoni ake omwe. Popanda kuyambitsa zotsatira za hypoglycemic.

Glucophage imakhudza thupi m'njira zitatu:

1. Poletsa gluconeogeneis ndi glyconolysis, amachepetsa kupanga shuga m'magazi a chiwindi.
2. Amakweza minofu cell insulin.
3. Kuchepetsa mayamwidwe m'matumbo.

Mosasamala za kuchuluka kwa shuga, mankhwalawo amachepetsa cholesterol, amathandizira mafuta acid kukhala gwero lenileni lamafuta, ndipo amathandizira kuthandizira kunenepa kwambiri.

Pazitali kwambiri pazogwira ntchito zimafikiridwa patatha maola atatu mutakhazikitsa. Achibale bioavailability ndi makumi asanu ndi limodzi peresenti. Mafuta mankhwala pafupifupi osadalira kudya.

• Monga chithandizo chachikulu cha matenda a shuga a mtundu 2, komanso kulephera kwa njira zina zamankhwala.
• Monga mbali ya zovuta mankhwala pochiza ana ndi achinyamata.
• Mankhwalawa matenda amtundu wa 2 shuga, ovuta kwambiri ndi kukhalapo kwa owonda kwambiri.

General zimatha mankhwala

Izi zikuphatikiza:

• Metformin ndi Glucofage ndi mankhwala antidiabetes. Cholinga chake chachikulu ndikuchepetsa kuchuluka kwa shuga, popanda kuwonjezera kudzipanga kwawo kwa insulin.
• Mankhwala amagwiritsidwa ntchito kupewera ndikuchiza zovuta zokhudzana ndi matenda a shuga.
• Mankhwalawa onse amathandizira kuchiza kunenepa kwambiri komwe kumayambitsa matenda a shuga.
• Mankhwala omwe ali pamwambawa ali ndi bioavailability womwewo ndi mayamwidwe.
• Metformin ndi Glyukofazh ali m'gulu la mitengo yomweyo.

Mankhwalawa alibe zosiyana zambiri. Nayi ena a iwo:

1. Malinga ndi malangizo, Metformin imagwiritsidwa ntchito pochiza matenda onse a shuga, ndipo Glucophage ndi yachiwiri yokha.
2. Metformin imalimbikitsa kuchuluka kwa glycogen mu chiwindi ndi minofu, ndipo glucophage ilibe katundu wotere.
3. Metformin imagwiritsidwa ntchito pochiza odwala achikulire okha, ndipo glucophage amagwiritsidwa ntchito pochiza ana ndi achinyamata.
4. malinga ndi malangizo, kudya zakudya zambiri kumatha kukhudza bioavailability wa Metformin, kudya zakudya sizimakhudza bioavailability wa Glucofage.

Zisonyezero zogwiritsira ntchito mankhwala

Choyambirira chomwe muyenera kulabadira mukamakambirana za kusiyana kwa mankhwalawa ndikuwonetsa momwe aliyense angagwiritsire ntchito.

Glucophage Amalandira kwa anthu odwala matenda ashuga a mtundu 2, ngati zakudya sizikhala ndi zotsatirapo zabwino. Komanso, mankhwalawa amatha kuthandiza odwala omwe, chifukwa cha kunenepa kwambiri, amakhala kuti amalimbana ndi insulin. Pankhaniyi, glucophage imaphatikizidwa ndi insulin.

Ponena za Metformin, mndandanda wazowonetsa kugwiritsidwa ntchito kwake ndikutali pang'ono. Metformin imagwiritsidwa ntchito:

1. Chithandizo cha matenda a shuga a mtundu woyamba ndi wachiwiri.
2. Kuyang'anira shuga wamagazi ngati matenda atha, ndipo kudya ndi kuchita masewera olimbitsa thupi sizithandiza.
3. Chithandizo cha ovary ya polycystic, komanso mothandizidwa ndi dokotala, motsogozedwa ndi iye.

Metformin, monga Glucofage, imachepetsa kuchuluka kwa shuga m'magazi am'magazi, komanso m'njira zingapo nthawi imodzi. Imafooketsa mayamwidwe am'magazi ndipo imathandizira kusokonekera kwake m'thupi. Mothandizidwa ndi chinthu ichi, minofu imakhudzidwa kwambiri ndi insulin, kuphatikiza kwake kwakukulu sikuchitika, kotero kunenepa kwambiri sikumayamba.

Mwa zina, Metformin imathandizira pamagetsi.

Glucophage ndi Metformin, pali kusiyana kotani?

Kupukusidwa ndi impso mkodzoKuphatikizidwa kwambiri m'mimba, kudya chakudya kumachepetsa kukula kwa njirayo,

Pafupifupi gawo limodzi mwa magawo atatu a yogwira ntchito imapukutidwa kudzera mu impso.Njira zogwiritsira ntchitoPakamlomo pokhaPakamlomo pokhaKuthamangaChithandizo chogwirira chimatha kufika patatha maola awiri ndi awiriPambuyo maola 2,5, kuchuluka kwa metformin m'magazi kumakhala kwakukulu, pambuyo pa maola 24-48, ndende imakhala yokhazikikaAnalogiBagomet, Glformin, Diaformin, Siofor, FormetinBagomet, Glycon, Gliminform, Glformin, NovoforminTerms a Tchuthi cha PharmacyKupezeka kokha ndi mankhwalaKupezeka kokha ndi mankhwalaKutalika kwavomerezedwaZimatengera kuchuluka kwa shuga m'magaziKutsimikiziridwa ndi dokotala kutengera kuchuluka kwa shuga m'magaziContraindication

• chidwi chamunthu chogwira ntchito,
• chikomokere kapena precomatosis
• mitundu yosiyanasiyana ya acidosis,
• matenda a impso ndi chiwindi
• kuchuluka kwa matenda aliwonse
• uchidakwa wambiri,
• kuvulala
• nthawi ya pakati komanso yoyamwitsa,
• opareshoni

• tsankho limodzi ndi zigawo za mankhwala,
• osakwana zaka khumi ndi zisanu
• acidosis
• coma ndi precomatose state,
• zigawenga
• kusowa kwamadzi
• matenda a impso (kuphatikizapo adrenal gland) ndi chiwindi,
• myocardial infaration
• odwala matenda ashuga phazi
• matenda opatsirana
• chikhalidwe chododometsa
• Zakudya zama hypocaloric
• uchidakwa wambiri,
• malungo
• mimba ndi mkaka wa m`mawere

Kodi ndi bwino kusankha?

Metformin ili ndi zambiri zowonetsa kuti imagwiritsidwa ntchito, mankhwala ake ndiwofalikira komanso odalirika, koma pamodzi ndi izi, mankhwalawa ali ndi zotsutsana zambiri.

Glucophage imaloledwa kuti idyedwe nthawi zambiri, koma nthawi yomweyo sioyenera kuthandizira matenda ena omwe Metformin adalembedwa.

Ndizosatheka kunena mosasamala kuti ndi iti mwa mankhwalawa omwe ndi abwino - onse ali ndi zabwino komanso zovuta zawo. Mankhwala okhawo ayenera kukhala adokotala okha.

Ngakhale kudziwa kusiyana pakati pa zinthuzi, muyenera kufunsa dokotala. Adzakhala ndi chidwi ndi njira zonse, magawo abwino komanso olakwika a mankhwalawa komanso machitidwe a thupi lanu.

Zambiri zamankhwala oyamba

Hypoglycemic wothandizila kukonzekera pakamwa monga mapiritsi. Glucophage imakhala ndi metformin hydrochloride monga gawo lake lalikulu. Kuphatikizika kwake kumadalira mlingo womwe umasankhidwa ndipo ukhoza kuchokera ku 0,5 g mpaka 1 g pa unit imodzi. Kuphatikiza apo, Glucophage imapatsidwa zina zowonjezera:

• Opadra KLIA kuti apange chipolopolo (filimu),
• Mmagnia wakuba,
• Povidone K 30.

Kuphatikizika kwa zosakaniza za mankhwala sikuyambitsa kupangidwira kwa insulin. Zodabwitsazi sizikhudza momwe munthu aliri mu mawonekedwe a hypoglycemic. Mankhwalawa amachepetsa kuchuluka kwa shuga, mosasamala nthawi yakudya ndi chakudya. Zotsatira zamankhwala, kuyendetsa ma membrane oyendetsa glucose kumayenda bwino; sikuti amatengeka kwambiri m'matumbo. Wodwala amapezeka ndi kusintha kwamphamvu kwa insulin minyewa, ndipo glucose amapangidwa m'chiwindi pang'onopang'ono.

Njira zonsezi zimakhudza osati thanzi la wodwalayo, komanso kulemera kwake. Madokotala pakapita maphunziro ambiri apeza kuti mapaundi owonjezera amachoka pang'ono kapena amakhala osasinthika pamlingo womwewo, zomwe zilinso zabwino kwa wodwalayo.

Kukhazikitsa kwa mankhwalawa Glucofage kumawonetsa kuti mankhwala amalembedwa kwa anthu odwala matenda ashuga a 2, ngati tebulo lamankhwala lingagwiritsidwe ntchito silikupatsani zotsatira zomwe mukufuna ndi masewera. Gwiritsani ntchito odwala omwe ali ndi kunenepa kwambiri. Kulandila kutha kuchitika mwa njira yayikulu komanso yokhayo ya mankhwala kapena kuphatikiza ndi insulin ya ana kuyambira zaka 10 komanso mankhwala a insulin ndi hypoglycemic zochizira odwala akulu.

Onetsetsani kuti mwawerengera: Malangizo atsatanetsatane ogwiritsira ntchito mankhwala a Siofor

Kapangidwe ndi kachitidwe ka zochita

Glucophage ili ndi metformin. M'malo mwake, Glucophage ndi mankhwala onse omwe ali ndi dzina la Metformin ndi ofanana, oyamba okha ndi mankhwala omwe ali ndi chizindikiro, ndipo ena onse ndi ma generics (ma generics, ichi ndi chiani?). Ndiwopanga omwe ndi kusiyana pakati pa mankhwala amtundu wina ndi wina.

Amayendedwe a metformin amatengera zotsatirazi zotsatirazi:

• Kuchepetsa kwa shuga ndi shuga ena m'matumbo a lumen,
• Kuchepetsa shuga wa chiwindi,
• Kuchulukana kwamphamvu kwa thupi lathu kupita ku insulin,
• Matenda a magazi lipids (amalepheretsa kukula kwa zovuta mu mawonekedwe a vasoconstriction ndi atherosclerosis),
• Zimalepheretsa kulemera.

Zochitika zonsezi zamankhwala zimaloleza odwala omwe ali ndi shuga kuti achepetse kuchuluka kwa insulini ndikusintha momwe alili. Mankhwalawa ndi abwino makamaka pochiza odwala matenda ashuga okalamba kapena onenepa kwambiri.

Palibe zosiyana pazomwe zikuwonetsedwa pakugwiritsa ntchito Metformin ndi Glucofage. Mankhwalawa amagwiritsidwa ntchito pochiza matenda amishuga amtundu wa 2 (ogwirizana ndi vuto la minofu yolumikizira insulin).

Contraindication ndi zoyipa

Ngakhale imagwira ntchito kwambiri, mankhwalawa ali ndi zotsutsana zosiyanasiyana:

• Kusalolera payekha,
• Ral pathology (kulephera kwaimpso),
• Hepatic pathology (cirrhosis, chiwindi kulephera),
• Kulephera kwa mtima (kukula kwa dyspnea panthawi yolimbitsa thupi, kutupa pamiyendo, m'mimba kapena m'mapapo),
• Kulephera kuwunikira (ntchito ya m'mapapo),
• Acute myocardial infaration,
• Ngozi yamitsempha yamagazi kwambiri,
• Anemia
• Matenda opatsirana
• Opaleshoni yayikulu kapena kuvulala
• Mowa
• Mimba komanso kuyamwa,
• Ana kapena ukalamba.

Mwa zosafunikira zomwe mungagwiritse ntchito mankhwalawa, mutha kupeza:

• Kuchepetsa thupi
• Kutsekula m'mimba, mseru, kutulutsa,
• Kutsika kosalamulirika kwa shuga m'magazi,
• Zotupa pakhungu.

Mankhwala onse awiriwa amapezeka mu mawonekedwe a mapiritsi. Kuti muyerekeze zowoneka bwino, ndikofunikira kuganizira mitengo ya phukusi la zidutswa 60.

Glucophage ingagulidwe kwa:

• 500 mg - 130 - 170 r,
• 500 mg Kutalika (kuchitapo kanthu) - 400 - 500 r,
• 750 mg Kutalika - 400 - 500 r,
• 850 mg - 150 - 250 r,
• 1000 mg - 250 - 350 r,
• 1000 mg Kutalika - 700 - 800 r.

Mitengo ya Metformin imasiyana ndi wopanga. Mapiritsi okwera mtengo kwambiri amasiyana ndi kampani Teva ndi Gideon Richter. Mtengo wamankhwala

• 500 mg - 110 - 300 r,
• 850 mg - 140 - 300 r,
• 1000 mg - 170 - 350 r.

Metformin, Siofor, Glucophage - ndibwino?

Chithandizo china chomwe chili ndi metformin pakuphatikizika kwake ndi Siofor. Monga mankhwala awiri omwe tawerengapo kale, ali ndi zofanana zonse.

Mankhwala onse ochepetsa shuga, akuluakulu pa metformin, amagwira ntchito mofanananira ndipo asonkhanitsa ndemanga zambiri kuchokera kwa madotolo ndi odwala. Pakati pawo, ndizosatheka kusankha oyimilira abwino kwambiri kapena oyipitsitsa - onse ali ndi ntchito yofanana. Kusankhidwa kwa mankhwalawa kumapangidwira wodwala aliyense payekhapayekha, kutengera luso lake, zomwe amakonda. Kusiyana kwake ndi Glucofage Long, komwe kumatha kumwa kamodzi kapena kawiri patsiku, pomwe Metformin imalembedwa mu 2 mpaka 3 Mlingo. Kugwiritsa ntchito mankhwalawa kwakanthawi kumapangitsa kuti odwala azikhala omasuka.

Nkhani yabwino ndiyakuti mankhwalawa onse amasinthana ndipo ngati kuli kotheka, mutha kusintha kuchokera ku Siofor kupita ku Glucophage, kuchokera ku Glucophage kupita ku Metformin, etc. Nthawi zina kusintha kwakung'ono kwa mankhwalawa kungafunike. Mukasinthana ndi piritsi limodzi kupita ku lina, muyenera kuwongolera kuchuluka kwa shuga m'magazi.

Mu shuga, onse a Glucofage ndi Metformin amawonetsa zotsatira zabwino. Ndi mankhwala oyenera, nthawi zambiri zimatha kuchepetsa shuga osati magazi okha, komanso mlingo wa insulin.

Metformin kapena Glucophage - ndibwino kuti muchepetse kunenepa?

Kugwiritsa ntchito mankhwalawa pofuna kuchepetsa thupi ndi nkhani yovuta. Ngati pali kulemera kwakukulu, komwe kumalumikizidwa ndi minofu yolumikizidwa ku insulin, ndiye kuti kugwiritsa ntchito Metformin kapena Glucofage kudzakhala koyenera. Koma chilichonse chomwe agwiritse ntchito ziyenera kuchitika mosamalitsa pazifukwa zamankhwala. Palibe kulemera kowonjezera komwe kumayenera kusinthidwa ndi mankhwala ngati palibe zifukwa zabwino zamtundu wamtunduwo pamtima, chiopsezo chotenga matenda a shuga, kuphatikizika kwa zina, ndi zina zambiri.

Mbali “yakuda” pa nkhaniyi ndi kugwiritsa ntchito mankhwalawa mosasamala. Pali ma forum ndi maupangiri ambiri komwe amalimbikitsidwa kugwiritsa ntchito mankhwala ochepetsa shuga kuti muchepetse kunenepa kwambiri. Zotsatira zake, azimayi omwe safunika kucheperachepera kapena amatha kuchepa thupi pogwiritsa ntchito zakudya zoyenera komanso masewera amatenga metformin. Izi zimabweretsa zovuta zambiri chifukwa cha kutsika lakuthwa kwa shuga m'magazi - kuyambira chizungulire chofewa mpaka kukomoka.

Kuyerekeza kwapakati pa mankhwala

Onse a Glucofage ndi Metformin ndi amodzi a mankhwala okhala ndi metformin. Onse othandizira a hypoglycemic amapangidwa mwanjira ya mapiritsi amkamwa mwachizolowezi komanso chokhazikika chamasulidwe achinthu. Muyenera kumwa mankhwalawa nthawi yomweyo monga kudya kadzutsa ndi / kapena chakudya chamadzulo, komanso njira yogwiritsira ntchito nthawi 3, komanso chakudya chamasana.

Zotsatira zazikulu za mankhwala ndikupondereza kupangika kwa glucose m'maselo a chiwindi (amakhudza glycogenolysis ndi gluconeogeneis). Izi zimakuthandizani kuti muchepetse shuga m'magazi, osalola kuti iwonjezeke mpaka kukhala ovuta. Ndikofunikira kuti thunthu metformin isalimbikitse kapangidwe ka insulin. Chifukwa chake, kutenga Glucofage ndi Metformin ndichizindikiro chodziwikiratu pakuchiza / kupewa matenda osokoneza bongo omwe amadalira matenda a shuga.

Zotsatira za metformin m'thupi:

• imawonjezera kukhudzika kwa zolandilira zotengera insulin ku mahomoni,
• kulephera kuthetsa pakamwa pouma ndi zizindikiro zina za hyperglycemia,
• imathandizira kukonzanso kwa glucose ndi ulusi wa minofu,
• linalake kapena loletsa kulemera,
• Ambiri odwala omwe ali ndi kunenepa kwambiri chifukwa cha matenda ashuga, kuwonda kwambiri,
• amachepetsa cholesterol, mafuta a triglyceride, lipDr lipoproteins,
• Imachepetsa mayamwidwe am'magazi m'mimba,
• imachepetsa kumverera kwanjala.

Mphamvu yotsitsa shuga ya metformine imakhala yapamwamba kuposa zinthu zina za hypoglycemic. Chifukwa chake, Glucofage, Metformin ndi mayendedwe awo amtheradi ali ndi chithandizo chokwanira kwambiri pamlingo wofanana. Kusiyana kwakukulu pazotsatira za zomwe zimachitika pokhapokha kugwiritsa ntchito zachinyengo.

Mankhwala osiyanasiyana

Mankhwalawa onse amapangidwa ndi opanga mayiko osiyanasiyana.Chifukwa chake, ali ndi kusiyana kochepa mu mitundu ya kumasulidwa ndi mtengo wake. Kumayambiriro kwa Novembala 2018, mtengo wa Metformin umasiyanasiyana pakati pa 9―608 rubles, ndi Glucofage - 43―1500 rubles. Kusiyana kwake kumatengera kuchuluka kwa mankhwalawa, nthawi ya mankhwalawa, malo opangira, kuchuluka kwa mapiritsi amodzi phukusi limodzi.

Zosiyanasiyana za othandizira a hypoglycemic pagome:

Kuyerekeza gawo

Mlingo wa metformin piritsi limodzi lokhala ndi mulingo wamba wamasulidwe

500 mg, 850 mg, 1000 mg

500 mg, 850 mg, 1000 mg

Mlingo wa metformin piritsi limodzi lokhathamiritsa

500 mg, 750 mg, 850 mg, 1000 mg

500 mg, 750 mg, 1000 mg

Mitundu ya zokutira piritsi

Mlingo wachilengedwe wamtundu wa Metformin umatulutsidwa popanda kuyala kapena ndi filimu kapena enteric zokutira

Mapiritsi a Glucophage ndi filimu

Mapiritsi otetezedwa osungika amakhala ovomerezeka-kapena amapangidwa popanda iwo

Glucophage Long amamasulidwa popanda chipolopolo

Malo opangira

Russia: Izvarino Pharma, Biochemist, Canonpharm Production, Vertex, Rapharma, Biosynthesis, Ozone, Medisorb

France: Merck Sante

Spain, Germany: Merck

Belarus: Chomera cha Borisov cha Madokotala

Czech Republic, Slovakia: Zentiva

Hungary: a George Richter

Ma Synonyms a Metformin ndi Glucofage

Gliformin, Langerin, Diaformin, Metfogamma, Siofor, Metospanin, Sofamet, Novoformin, Formmetin, ma analogues ena onse (mankhwala omwe ali ndi gawo limodzi la metformine)

Kukonzekera kwazinthu ziwiri zomwe zimakhala ndi metformine

Galvus Met, Bagomet Plus, Glimecomb, Amaril M, Avandamet, Yanumet

Anosological analogues (mankhwala omwe ali ndi vuto la hypoglycemic)

Vildagliptin, Glibenclamide, Glyclazide, Glimepiride, Rosiglitazone, Sitagliptin

Yang'anani! Kuchita kwa mapiritsi a Metformin nthawi imodzi sikuloledwa kuonjezera Glucofage. Othandizira onsewa ndiofananira mwamtheradi wina ndi mnzake, motero, bongo la metformin limachitika.

Kugwiritsa ntchito mankhwala

Glucophage kapena Metformin podzichiritsa kapena kuti achepetse kulemera kwa thupi kumayikidwa pakadalibe zotsatira za zakudya komanso masewera olimbitsa thupi. Mankhwalawa aliwonse amagwiritsidwa ntchito pochiza / kupewa hyperglycemia, mtundu wa 2 matenda a shuga, prediabetes, komanso kuchuluka kwa insulin. Pankhani ya kunenepa kwambiri, polycystic ovary, matenda a shuga 1 ndi matenda ena, imodzi mwa mankhwalawa imaphatikizidwa ndi zovuta.

Ndalama zoyenera kutenga Glucofage kapena Metformin:

• Mapiritsi a nthawi zonse amatulutsidwa - ndi chakudya m'mawa kapena madzulo, maola 12 aliwonse (chakudya cham'mawa ndi chakudya chamadzulo), m'mawa / chakudya chamadzulo / madzulo, nthawi yamadzulo.
• Mapiritsi otsekemera - panthawi imodzi ndi chakudya 1 nthawi / tsiku.

Palibe zosiyana poyerekeza Glucofage ndi Metformin molingana ndi njira yogwiritsira ntchito. Mapiritsi amatengedwa ndi chakudya katatu kapena tsiku, kutsukidwa ndi madzi 150-200 ml. Mankhwala othandizira tsiku lililonse ndi 500-3000 mg. Sizoletsedwa kupitilira kuchuluka kwa chinthu 3 3 metformine / maola 24: padzakhala mankhwala ochulukirapo omwe amakhala ndi zovuta zowopsa m'moyo.

Zotsatira zoyipa zamankhwala

Palibe kusiyana pakati pa Metformin ndi Glucophage pakuwonetsa zovuta, popeza mankhwalawa onse ali ndi metformin.

Metformin ya zinthu zomwe zimayambitsa:

• kusanza
• nseru
• kutulutsa (phokoso),
• kupweteka m'mimba, matumbo,
• chimbudzi kapena mafinya,
• kulawa kosokoneza
• erythema
• chitsulo
• anorexia (kusowa kwa chakudya),
• lactic acidosis,
• megaloblastic anemia (chifukwa cha mayamwidwe a vitamini B₉, B₁₂),
• dermatitis
• urticaria.

Pakuwunika kochepa, pali mawu akuti Glucophage amachititsa zotsatira zoyipa zochepa poyerekeza ndi Metformin. Uku ndikutanthauzira kolakwika kwa chidziwitso, chifukwa mankhwalawa onse ali ndi zomwezo mumtundu womwewo. Kusiyana kwa zotsatirapo kumachitika katatu: mankhwala osakhalitsa amatengedwa thupi litakhala kuti limazolowera mapiritsi wamba, munthuyo amalekerera metformin bwino kapena saphwanya malamulo a kudya mankhwalawo.

Contraindication chifukwa chomwa mankhwalawo

Glucophage sichimatchulidwa konse ndi Metformin, chifukwa awa ndi fanizo lathunthu . Mankhwalawa amaletsedwa kugwiritsidwa ntchito ngati akutsutsana ndi kapangidwe kake, ndipo amaletsedwa ana osakwana zaka 10. Mankhwalawa sagwiritsidwa ntchito kawirikawiri panthawi yapakati komanso pakubala. Ngati amamulembera mayi woyamwitsa, mwanayo amamugulitsa chakudya ndi mwana wakhanda.

Zotsutsana zina ndi malire:

• Zakudya zomwe zili ndi kalori yofanana ndi chizindikiro cha ≤ 1000 kcal,
• kusowa kwamadzi
• matenda aimpso, chiwindi,
• kupuma / kulephera kwa mtima ndi zina zomwe zimayambitsa hypoxia,
• uchidakwa kapena uchidakwa. (metformin siyigwirizana ndi Mowa),
• ma virus, bakiteriya ndi matenda ena opatsirana,
• matenda ashuga ketoacidosis, chikomokomo, kholo,
• vuto la hypoglycemic,
• metabolic kapena lactic acidosis,
• kuvulala, kugwira ntchito m'malo akuluakulu a thupi.

Kuchepetsa kwakanthawi kutenga Metformin kapena Glucofage ndi chithandizo cha opaleshoni kapena kuwunika pogwiritsa ntchito njira yokhala ndi ayodini. Mapiritsi a Metformine amasiya kumwa masiku angapo njirayi isanachitike.

Mankhwala osokoneza bongo

Mukachulukitsa tsiku lililonse kuposa 3 ga kapena kumwa Glucophage nthawi imodzi ndi Metformin, bongo limachitika. Amawonetsedwa ndi kukula kwa lactic acidosis.

Zizindikiro za mankhwala osokoneza bongo a Metformin kapena Glucofage:

• kusakhala ndi chidwi, kulephera kudya,
• kupweteka kwa angina
• kupweteka kwa minofu, kukokana,
• chisokonezo
• youma mucous nembanemba
• Zizindikiro za hepatitis (chikasu cha pakhungu, sclera),
• kulephera kupuma
• vuto la kugona
• kulephera kwa mtima
• kusanza
• kutsegula m'mimba
• kupweteka kwam'mimba
• osangalatsa,
• Matenda osakwanira
• metabolic acidosis.

Chifukwa cha kusowa kwa chithandizo chamankhwala, hyperlactacidemic chikomokere ndi imfa zimachitika. Mankhwala osokoneza bongo a Glucophage kapena Metformin amachotsedwa ndi hemodialysis limodzi ndi makonzedwe a mankhwala a dalili.

Ndemanga za ena

Endocrinologists amati odwala omwe ali ndi matenda ashuga amatha kulekerera kayendetsedwe ka mapiritsi a Metformin kapena Glucofage nthawi zambiri poyerekeza ndi mankhwala omwewo ndi chiwopsezo chamasulidwa. Zizindikiro za dyspepsia zimawonekera kumayambiriro kwa mankhwalawa, kotero milungu iwiri yoyambirira anthu ayenera kumwa mankhwalawa.

Mwa anthu omwe ali ndi shuga wamba, Glucofage ndi Metformin amaloledwa kugwiritsidwa ntchito poyeretsa thupi, mankhwalawa am'mimba mwa polycystic kapena matenda ena. Kutengera zofunikira za malangizo ndi malingaliro a dokotala, palibe kuwonongeka kwaumoyo pazotsatira za hypoglycemia kapena kukula kwa lactic acidosis.

Popeza mankhwalawa onse ali ndi katundu omwewo, posankha mankhwala abwino kwambiri, dokotala amatengera kuchuluka kwa kumasulidwa kwa chinthucho. Pazovuta zovuta, mapiritsi a nthawi yayitali amalimbikitsidwa. Odwala ambiri amagula Metformin chifukwa imawononga ndalama zochepa kuposa Glucofage.

Pambuyo pake

Zambiri pazamankhwala zimatengedwa kuchokera ku zolemba zamankhwala ndi zolemba za opanga, zowonjezeredwa ndi kuyesa kwa malingaliro a madokotala, odwala ndi anthu omwe amagwiritsa ntchito chida chocheperako. Zambiri zomwe zalembedwa mu Metformin, Glucofage ndi mayendedwe awo zimaperekedwa pofuna kudziwa. Mulingo woyenera wa mankhwala, mlingo ndi nthawi ya maphunzirowa ayenera kulimbikitsidwa ndi endocrinologist kapena kupita kwa dokotala wina.

Zindikirani! Asayansi akupitilizabe kufufuza za mankhwala a metformin. Tsopano zatsimikizika kuti ndizothandiza popewa khansa zamtundu uliwonse, chithandizo cha kusaberekanso, matenda amkati, matenda amtima, matenda a senile.

Vidal: https://www.vidal.ru/d drug/metformin-5
Radar: https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGu>

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Zambiri pazomwe zikuchitidwa ndi Metformin

Mankhwala othandizira odwala matenda a shuga ndi mankhwala a pakamwa a hypoglycemic. Chopanga chachikulu ndi metformin hydrochloride womwewo mu mtundu womwewo wa mtundu wakale. Mndandanda wazopeza zimasiyana pamakonzedwe awa. Chifukwa chake, mu mapiritsi awa muli zinthu monga:

• Propylene glycol,
• Povidone
• Talc,
• Wowuma chimanga
• Titanium dioxide ndi ena

Polyethylene glycol 400 ndi 6000, komanso hypromellose, amagwiritsidwa ntchito kupanga chovala cha filimuyo. Mankhwala amathandizidwanso kwa odwala omwe ali ndi mtundu wofanana ndi matenda a shuga 2, koma amtundu wa insulin wokha, ngati palibe chifukwa chochita zolimbitsa thupi. Amagwiritsidwa ntchito ngati othandizira othandizira pochizira komanso mapiritsi ena a hypoglycemic.

Kuyerekezera Mankhwala

Ngati mukuganiza zomwe zingakuthandizeni kuchepetsa kunenepa: Metformin kapena Glucofage, muyenera kuganizira kuwonongeka kwachiwiri. Mankhwala amatha kuzolowera zochitika zina. Ndiye kuti, Glucophage imapanga chiwonetsero cha mphamvu yake ya hypoglycemic pokhapokha kuchuluka kwa glucose m'magazi a anthu kukwera. Ngati chizindikirochi ndichabwinobwino, palibe chifukwa chotsikirira, ndiye kuti thupi silimachitanso chimodzimodzi.

Kusiyana pakati pa mankhwalawo kuli mkati mwake momwe kukulira kwamphamvu kwa minofu yaumunthu kum insulin. Chifukwa chodziwikiratu kwa zinthu zomwe zimagwira, kuyamwa kwa glucose ndi thirakiti lam'mimba ndikutsekedwa, zomwe zimapangitsa kuchepa kwa magazi. Madokotala amati mankhwalawa Glucofage amagwira ntchito mwachangu, zomwe zimapangitsa kuti minye ya wodwalayo isakanikirane ndi zigawo zina za mankhwala.

Metformin, nayenso, siyitsogolera pakupanga insulini, motero glucose satsika kwambiri. Njira yodziwikitsira ndizosiyana ndi zomwe zimagwiritsidwa ntchito ndi mankhwala akale. Zotsatira zake, metformin hydrochloride imakhala munjira yopanga shuga, kuletsa njirayi, yomwe imapangitsa kutsika kwa kuchuluka kwa zinthu. Nthawi yomweyo, kuchuluka kwa glucose amene amakhala m'magazi a wodwala akamadya kumachepa. Zonsezi zimakhala cholepheretsa mapangidwe a matenda a shuga, kupatula kukula kwa chikomokere mwa iye.

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Chifukwa chake, poganizira zamomwe zimapangidwira mankhwala a Glucofage ndi Metformin, zitha kukhazikitsidwa kuti kusiyana kwake ndi kachitidwe ka zochita pa thupi la munthu. Koma izi ndizotalikira kusiyanasiyana konse. Madokotala nthawi zambiri amapereka metformin kuti alembe 1 ndikulemba matenda ashuga a 2, anthu omwe ali ndi kunenepa kwambiri. Mu mankhwala, kuphatikiza kwa mankhwalawa ndi insulin kumapezeka.

Mukamasankha njira yamankhwala, katswiri adzaonetsa mawonekedwe a Metformin - kupewa mavuto komanso kukulitsa kwa matenda a mtima.

Ndipo tsopano mwatsatanetsatane ku funso loti Glucophage amasiyana bwanji ndi Metformin. Zikuwoneka kuti ndizofanana zomwe zikuwonetsa: kusowa kwa zotsatira za chithandizo cha matenda ashuga komanso kugwiritsa ntchito zakudya, zolimbitsa thupi, koma matenda a mtundu 2 wokha. Kuphatikiza apo, Glucophage Long imakhala ndi mphamvu yayitali, yomwe imawonetsa pang'onopang'ono zomwe zimagwira ndipo zimakhudzanso thupi la munthu. Opanga samalepheretsa kugwira ntchito kwa mankhwalawa chifukwa chosiyana ndi mankhwala a Metformin omwe amagwira ntchito mwachangu.

Mankhwala Glucophage Long amawoneka muubwino wambiri:

• Kumanga michere ya protein,
• Matendawa mabiliyoni ambiri,
• Bwino amachepetsa ndende ya magazi,
• Amachotsa mavuto ndi zovuta zama metabolic.

Koma ngakhale mndandanda wosangalatsa woterewu samapangitsa mankhwalawo kukhala osiyana ndi ena. Satha kusintha chakudya chokwanira kwa wodwala matenda ashuga.

Mankhwalawa alibe zabwino zokha, Glucophage poyerekeza ndi Metformin amataya pang'ono potsatira zotsatira zoyipa. Nthawi zambiri, mankhwalawa siabwino kwa odwala, chifukwa chake ndizosatheka kuti mudzipatseni nokha mankhwala, ndipo ngati pali zizindikiro zosasangalatsa panthawi yopereka chithandizo, muyenera kufunsa dokotala.

Mtengo wa mankhwalawa umavutitsanso odwala, chifukwa Metformin ndi yotsika mtengo. Koma okwera mtengo kwambiri ndi Glucophage Long. Ndi dokotala wokhayo amene angadziwe zobisika za kusiyana pakati pa mayina ogulitsawa pafupifupi chithandizo chofanana. Kusiyanitsa pakati pawo ndikochepa, koma cholinga chake chimatengera magawo angapo a anthu:

• Mtundu wa matenda ashuga
• Gawo la kunenepa kwambiri,
• M'badwo wodwala
• Kuphatikizika kwa mankhwala omwe amayenera kumwa panthawi ya mankhwala,
• Mayendedwe ophatikizidwa
• Hypersensitivity kwa wotchuka wina, etc.

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Kuletsedwa kotheratu

Mankhwala onse omwe amapangidwa pamaziko a metformin hydrochloride ali ndi zotsutsana zingapo komanso zoyipa, ndipo kugwiritsa ntchito molakwika kumatha kuyambitsa mavuto ena. Iyenera kuthandizidwa makamaka ngati mayi angagwiritse ntchito mapiritsi a zakudya izi.

Ngakhale pali kusiyana pang'ono pakati pa mankhwala Glucofage ndi Metformin, onse awiriwa amatha kuyambitsa mavuto:

• Kuthekera kwa matenda a anorexia kukuchulukirachulukira,
• Zimabweretsa kuchepa kwakukulu kwa vitamini B, ndipo izi zimakakamiza wodwala kuti atenge mankhwala ena owonjezera,
• Zizindikiro zoyipa (kutsegula m'mimba, kusanza, kupweteka m'mimba),
• Chiwopsezo chotenga ma pathologies am'mimba,
• Matenda a pakhungu (zotupa, mafupa),
• Anemia
• Kusintha kwa kukoma (mwachitsanzo, kukoma kwachitsulo).

Kukhazikika kwa mankhwalawa kumapangitsa kuti thupi lizikundana, ndipo izi zimapanga lactic acidosis. Mkhalidwe wa matenda a impso ukuwonjezereka. Simungathe kupereka mankhwalawa kwa amayi apakati ndi amayi omwe akuyamwitsa. Ndi kusalolera chimodzi mwazigawo, mankhwalawa samamwa. Mankhwala oterewa amatsutsana ndikulephera kwa mtima, ndimomwe amalembera m'mbuyomu.