Kodi pali kusiyana kotani pakati pa aspirin ndi acetylsalicylic acid?

Kodi acetylsalicylic acid ndiofanana ndi asipirini? Kodi pali kusiyana kwakukulu pakati pa mankhwalawa? Aspirin ndi acetylsalicylic acid amagwiranso ntchito zomwezo, ndipo amagwiritsidwa ntchito pazinthu zamankhwala monga mtima, kuchiritsa, kuchita opareshoni. Aspirin ndi dzina lamalonda la acetylsalicylic acid.

Mapiritsi a Aspirin ali m'gulu la mankhwala omwe si a anti -idalidal anti-yotupa, mankhwala othandizira omwe ali acetylsalicylic acid. Imapezeka mwanjira ya mapiritsi, omwe ali ndi 500 mg yogwira ntchito, limodzi ndi wowuma wa chimanga ndi cellcrystalline cellulose. Makamaka, mankhwalawa amagwiritsidwa ntchito ngati mankhwala osokoneza bongo, komanso antipyretic.

Kutenga mapiritsi awa pakamwa, mu mulingo wa 300 mg mpaka 1 g, kumachepetsa ululu, kumathandizanso kupweteka m'misempha ndi malo olumikizirana mafupa, komanso limakupatsani mwayi wochepetsa kukhalapo kwa kutentha pang'ono, mwachitsanzo, kuzizira kapena chimfine. Mlingo womwewo umagwiritsidwa ntchito kuti muchepetse kutentha kwa thupi.

Mphamvu za mankhwalawa zimaloleza kuti zigwiritsidwenso ntchito ngati mukutupa kwambiri, pomwe Mlingo wokwera umagwiritsidwa ntchito kuposa mankhwala ena onse.

Mankhwala angagwiritsidwenso ntchito poletsa mapangidwe magazi, omwe amakwaniritsidwa mwa kupondereza mapangidwe ophatikizika am'magazi.

Mukamamwa mankhwalawa, pali zotsutsana zotsatirazi:

Kugwiritsa ntchito mankhwalawa ndizoletsedwa pamaso pa zinthu zomwe sizigwirizana ndi zonse zomwe zimagwira palokha komanso pazinthu zake. Kuphatikiza apo, sikulimbikitsidwa kupereka mankhwalawa kuti mugwiritse ntchito ngati mukupezeka magazi.

Otsatirawa amatengedwa ngati milandu yotsutsana:

mogwirizana makonzedwe ant antagagants,
osakwanira enzyme ya cytosolic,
matenda a mphumu
kuwonongeka kwaimpso,
kukhalapo kwa matenda osachiritsika am'mimba ndi duodenum,
matenda ashuga
gout
osakwana zaka 12
mimba
yoyamwitsa.

Pamaso pa chimodzi mwa ziwonetserozo za wachibale, mankhwala angathe kumwedwa pokhapokha ngati dokotala walandira.

Kuwonetsedwa kwa zoyipa kumatha kuchitika mwa mawonekedwe a hypersensitivity mu mawonekedwe a totupa pakhungu, komanso kuchepa kwamapulasitiki m'magazi komanso kumachitika kupweteka m'mimba. Zowonetsera zawo zilizonse zimafuna kuti atuluke ndi kulandira chithandizo kwa adokotala.

Kulandila kwa aspirin, malinga ndi malangizo, kumachitika mkati mwa chakudya, ndikatsuka ndimadzi okwanira. Malire a kudziwongolera popanda kukambirana ndi dokotala ndi ochepa masiku 5. Mu gawo limodzi, amamulembera kuchuluka kuchokera pa 300 mg mpaka 1 g, kuti atha kubwereza pambuyo pa maola 4-8. Mlingo wokwanira tsiku lonse ndi 4g.

Acetylsalicylic acid

Mankhwalawa amapezeka mu khabati yamankhwala mabanja ambiri.

Kutchulidwa koyamba kwa acetylsalicylic acid kunayambira kumapeto kwa zaka za zana la 19, ndipo zimagwirizanitsidwa ndi dzina la chemist wachichepere Felix Hoffman, yemwe panthawiyo anali wogwira ntchito ku kampani yopanga mankhwala a Bayer. Malingaliro ake akulu anali kupeza mankhwala omwe angathandize bambo ake kuchepetsa ululu m'malo mwake. Uku kunali kusankha kwa sodium salicylate kwa wodwala. Chokha chomwe chidabweza chinali kulephera kwa wodwalayo kuti atenge, chifukwa chakuti mankhwalawa adayambitsa kupweteka kwa m'mimba.

Patatha zaka ziwiri, patent ya mankhwala omwe amatchedwa aspirin adapezeka ku Berlin, komwe acetylsalicylic acid imagwira ngati chinthu chogwira ntchito.

Mankhwalawa ali ndi mphamvu yotsutsa-yotupa, ya analgesic ndi antipyretic, ndipo, nthawi yomweyo, amalepheretsa njira zamagulu ena.

Zizindikiro zapadera zogwiritsidwa ntchito

Kusamala makamaka kuyenera kuchitika pofotokoza kwa odwala omwe ali ndi matenda osiyanasiyana a chiwindi ndi impso, mphumu ya bronchi, zilonda zam'mimba komanso magazi m'matumbo.

Gwiritsani ntchito ngakhale Mlingo wochepa ungachepetse uric acid excretion, womwe umayambitsa matenda a gout mwa odwala omwe amakonda matendawa. Ngati ndi kotheka, kugwiritsa ntchito nthawi yayitali kuyenera kuyang'aniridwa ndi dokotala wanu ndikuwunika kuchuluka kwa hemoglobin.
Masiku 5-7 asanachitidwe opareshoni komanso nthawi yotsiriza, mankhwalawa ayenera kuyimitsidwa.
Kugwiritsa ntchito: Mankhwala a gululi amagwiritsidwa ntchito pa angina pectoris, chiwopsezo chachikulu cha kugunda kwamtima, matenda a mtima.

Zotsatira zoyipa

Kugwiritsa ntchito nthawi yayitali kungayambitse kusokonezeka kwamitsembere yamanjenje monga chizungulire, tinnitus, ndi kuwonongeka kwa mawonekedwe. Pangakhalenso kuwonjezeka kwa magazi nthawi, kuwonongeka kwa impso, ndi kulephera kwaimpso. Muyenera kusamala mukamamwa mankhwalawa amayi apakati.

Kodi ndi zofanana kapena zofanana?

Kodi pali kusiyana pakati pa mankhwalawa? Ngati muzolowera malangizo amomwe mankhwalawa amagwiritsa, ndiye kuti kusiyana kwake ndi mlingo. Aspirin akupezeka mu gawo la 100, 300 ndi 500 mg. Acetylsalicylic acid amapangidwa monga mapiritsi, omwe 250 ndi 500 mg.

Mankhwala

Mphamvu ya analgesic imachitika chifukwa cha zonse zapakati komanso zotumphukira. Ngati zotupa zachepa, zimachepetsa kutentha poyenda pamalo opatsirana kutentha.

Kukakamira ndi kuphatikiza kwa mapulateletikomanso thrombosis kuchepa chifukwa cha kuthekera kwa ASA kupondereza kaphatikizidwe ka thromboxane A2 (TXA 2) m'mapulateleti. Zoletsa kaphatikizidwe prothrombin (coagulation factor II) mu chiwindi ndipo - muyezo woposa 6 g / tsiku. - amachulukitsa PTV.

Pharmacokinetics

Mafuta a mankhwala atatha kumwa mkatikati ali pafupi kwathunthu. Nthawi yochotsa theka la ASA yosasinthika siyopitilira mphindi 20. TCmax ASA mu - 10-20 mphindi, salicylate yonse yochokera - kuyambira 0.3 mpaka maola 2.0.

Pafupifupi 80% ya dziko lomangidwa acetylsalicylic ndi salicylic acid. Ntchito yachilengedwe imapitilira ngakhale chinthucho chikakhala kuti chili m'mapuloteni.

Wopangidwira m'chiwindi. Amachotsa impso. Kutupa kumakhudzidwa ndi mkodzo pH: akaphatikizika, amachepetsa, ndipo akamera, amakula.

Magawo a Pharmacokinetic zimatengera kukula kwa mlingo womwe umamwa. Kuthetsa kwa thupilo sikuwonekera. Komanso, mu ana a 1 chaka cha moyo, poyerekeza ndi achikulire, amayamba pang'onopang'ono.

Contraindication

Kulandila ASA ndikotsutsana mu:

Mphumu,
pa kuchuluka zotupa ndi zotupa zodyera kumimba,
magazi am'mimba / m'mimba,
kusowa kwa Vitamini K,
hemophilia, hypoprothrombinemia, hemorrhagic diathesis,
Kuperewera kwa G6PD,
matenda oopsa a portal,
Kulephera kwa impso / chiwindi
mawa
munthawi yamankhwala (ngati mlingo wa sabata umaposa 15 / mg),
gouty nyamakazi, gout,
(miyezi itatu yoyambilira ndi itatu ndiyotsutsana kotheratu),
Hypersensitivity kwa ASA / salicylates.

Kugwiritsa ntchito ASA mu cosmetology

Acetylsalicylic acid chigoba chakumaso chimakupatsani mwayi kuti muchotse kutupa, muchepetse kutupa, chotsani redness, chotsani masanjidwe akufa a maselo akufa ndi ma pores oyera.

Mankhwalawa amawuma khungu ndipo amasungunuka kwambiri m'mafuta, zomwe zimapangitsa kuti ikhale yoyenera kugwiritsidwa ntchito ngati mankhwala a ziphuphu: mapiritsi osungunuka ndi madzi, oikidwa pazinthu zopaka pankhope kapena owonjezera kuti apangidwe ndimasamba amaso.

Acetylsalicylic acid kuchokera ziphuphu imagwira ntchito bwino limodzi ndi mandimu kapena uchi. Yothandiza kuthetsa mavuto a khungu ndi chigoba ndi dongo.

Kukonzekera chigoba cha mandimu-mapiritsi, mapiritsi (6 zidutswa) amangoyika pansi ndi madzi atsopano pokhapokha utapezeka waukulu. Kenako mankhwalawo amawonekera ziphuphu zoyipa natsalira mpaka atawuma.

Chigoba chokhala ndi uchi chimakonzedwa motere: mapiritsi (zidutswa zitatu) amasungunuka ndi madzi, kenako, ndikasungunuka, osakanizidwa ndi supuni ya tiyi ya 0,5-1.

Kuti akonze dongo, mapiritsi 6 ofinidwa a ASA ndi supuni ziwiri (supuni) za dongo loyera / buluu ziyenera kusakanikirana ndi madzi ofunda.

Bongo

Mankhwala osokoneza bongo atha kuchokera ku:

chithandizo chautali cha ASA,
limodzi makonzedwe a mankhwala okwanira.

Chizindikiro cha bongo ndi salicylism syndrome, yowonetsedwa ndi malaise, hyperthermia, tinnitus, nseru, kusanza.

Olimba limodzi spasms, kusokonekera, kuchepa mphamvu kwa madzi, mapapu osakhala a cardiogenic, kuphwanya kwa CBS, kudabwitsa.

Ngati odwala a ASA ali ndi vuto lalikulu, wozunzidwayo ayenera kugonekedwa kuchipatala msanga. Mimba yake imatsukidwa, kupatsidwa, kufufuzidwa ndi CBS.

Kutengera momwe WWTP ilili komanso kuchuluka kwa madzi ndi ma elekitirodi, kuyambitsa mayankho kungapangidwe, sodium citrate ndi sodium bicarbonate (monga kulowetsedwa).

Ngati mkodzo pH ndi 7.5-8.0, ndipo kuchuluka kwa madzi am'magazi opitilira 300 mg / l (mwa mwana) ndi 500 mg / l (mwa munthu wamkulu), chisamaliro chofunikira chimafunikira zamchere zamchere.

Ndi kuledzera kwambiri kuchitidwa, kubwezeretsa madzi am'madzi, kupereka mankhwala.

Kuchita

Kupititsa patsogolo kuopsa kukonzekera kwa barbiturate,valproic acid, methotrexateZotsatira zamankhwala otulutsa pakamwa, zamwano, mankhwala a sulfa.

Zofooka okodzetsa (potaziyamu-wotaya ndi kutulutsa kwina), antihypertensive mankhwala ACE zoletsauricosuric othandizira.

Ndi munthawi yomweyo kugwiritsa ntchito mankhwala antithrombotic, manga,anticoagulants kumawonjezera mwayi wokhetsa magazi.

GCS imathandizira poizoni wa ASA pa mucous nembanemba wamimba m'mimba, kuwonjezera kukula kwake ndikuchepetsa ndende ya plasma.

Ikagwiritsidwa ntchito nthawi yomweyo ndi mchere, Li imakulitsa kuchuluka kwa plasma ya Li + ions.

Imapititsa patsogolo poledzera wama mowa pakhungu la m'mimba m'mimba.

Malangizo apadera

Mankhwala ayenera kugwiritsidwa ntchito mosamala mwa anthu omwe ali ndi matenda a impso ndi chiwindi, ndi magazi ochulukirapo, mtima wosakhazikika, munthawi ya mankhwala opatsirana, komanso anthu omwe ali ndi mbiri yakale yazotupa ndi zotupa m'mimba ndi / kapena m'mimba / magazi m'matumbo.

Ngakhale muyezo yaying'ono, ASA imachepetsa kuchulukitsa. uric acidkuti odwala omwe atengeke mosavuta amatha kuyambitsa kuwopsa gout.

Mukamamwa mankhwala ochuluka a ASA kapena kufunika kwa chithandizo chanthawi yayitali ndi mankhwalawa, ndikofunikira kuwunika pafupipafupi msanga dokotala.

Monga othandizira-kutupa, kugwiritsa ntchito ASA muyezo wa 5-8 g / tsiku. ochepa chifukwa chowonjezeka chiopsezo chotsatira cham'mimba.

Kuchepetsa magazi munthawi ya opareshoni komanso munthawi ya kugwira ntchito, kutenga salicylates kumaimitsidwa masiku 5-7 musanachite opareshoni.

Mukamamwa ASA, muyenera kukumbukira kuti mankhwalawa amatha kumwa kwa masiku osaposera 7 popanda kufunsa dokotala. Monga antipyretic ASA, amaloledwa kumwa osaposa masiku atatu.

Mankhwala okhala ndi chinthu

ASA ikalira, singano zopanda utoto kapena monoclinic polyhedra yokhala ndi kukoma wowawasa pang'ono amapangidwa. Ma kristalo amakhazikika mlengalenga, koma ndi chinyezi chowonjezereka, pang'onopang'ono hydrolyze mpaka salicylic ndi acetic acids.

Thupi lomwe limapangidwa ndi mawonekedwe oyera ndi ufa wa makristalo oyera. Maonekedwe akununkhira amchere acetic ndikuwonetsa kuti chinthucho chimayamba hydrolyze.

kachilombo , popeza kuphatikiza koteroko kumatha kuyambitsa mkhalidwe wowopsa wa mwana - Matenda a Reye.

Mwa makanda, salicylic acid imatha kulowa m'malo chifukwa albin bilirubin ndi olimbikitsa chitukuko encephalopathy.

ASA imalowa mosavuta m'madzi onse amthupi ndi zimakhala, kuphatikiza zamadzimadzi, zotumphukira ndi peritoneal fluid.

Pamaso pa edema ndi kutupa, kulowa kwa salicylate kulowa kolumikizira kwamkati kumathandizira. Mu siteji ya kutupa, m'malo mwake, imachepera.

Gwiritsani ntchito panthawi yoyembekezera komanso poyamwitsa

Acetylsalicylic acid amatsutsana panthawi yapakati. Makamaka m'miyezi yoyamba komanso yomaliza ya bere. Mu magawo oyambilira, kumwa mankhwalawa kumatha kuwonjezera mwayi wokhala ndi vuto lakubadwa, pambuyo pake - kutenga kwambiri mimba ndi kufooketsa ntchito.

ASA ndi ma metabolites ang'onoang'ono amalowera mkaka. Pambuyo popereka mankhwala mwangozi, mavuto sanawonedwe mwa makanda, chifukwa chake, monga lamulo, kusokonezeka kwa kuyamwitsa sikofunikira.

Ngati mayi akuwonetsedwa chithandizo chamanthawi yayitali ndi ASA yayikulu, ndikofunikira kuti muchepetse chiwindi B.

Malangizo ogwiritsira ntchito:

Acetylsalicylic acid ndi mankhwala omwe amatchulidwa odana ndi kutupa, antipyretic, analgesic ndi antiaggregant (amachepetsa kuphatikiza kupatsidwa zinthu za m'magazi).

Ndi chinthu chomwecho

Aspirin ndi acetylsalicylic acid ndi amodzi amodzi. Mtundu wamalonda wa dzinalo - aspirin, wavomerezedwa padziko lonse lapansi, koma mayina a analogues, mankhwala ophatikizika a salicylic acid mu kutulutsa kwadziko lonse - pafupifupi 400 (mopyrine, aspilite, apo-asa, ndi zina). Ma salicylates amapezeka ku bark ya msondodzi, womwe wagwiritsidwa ntchito ngati mankhwala ochizira matenda ochizira malungo, kufinya, komanso kupweteka.

Amawaganizira kuti ndi nambala 1 wa mankhwala ammutu komanso kutentha kwambiri kwa thupi. Komanso acetylsalicylic acid ali ndi anti-yotupa, choletsa kupanga ma prostaglandins - oyimira njira yotupa mthupi.

Mphamvu ya antipyretic ya asidi imeneyi imatheka chifukwa chakulepheretsa kugwira ntchito pakati paubongo komwe kumayang'anira thermoregulation. Kutentha kukakwezeka kwambiri ndikuvulaza thupi, piritsi mwachangu ndipo kwa maola angapo "limagogoda" pazikhalidwe zokhazikika.

Malingaliro a madotolo

Dmitry Vladimirovich, dokotala wa opaleshoni ya mtima: “Mankhwala othandiza komanso otsika mtengo oteteza matenda a mtima. Ndikupangira mapiritsi okhala ndi mankhwala othandizira kuti achepetse zovuta m'matumbo a m'mimba. "

Konstantin Vitalievich, phlebologist: "Mankhwalawa apitilizabe kuthandizira kuzizira, zizindikiro zakuchoka ndi ma syndromes opweteka. Mukamagwiritsa ntchito nthawi yayitali, mumatha kudwala zilonda zam'mimba, zomwe zingathe kutaya magazi ambiri m'mimba. "

Sergey Alexandrovich, wazachipatala: “Aspirin imatha kudziwika ngati mankhwala a zaka zana lino, omwe ali ndi zabwino zake ndi zotsatirapo zake zoyipa. Simungathe kuzitenga mopepuka, poganiza kuti ndizofanana ndi mavitamini. Imapatsirana chifukwa cha matenda aimpso komanso chiwindi. ”

Ndemanga za Odwala pa Aspirin ndi Acetylsalicylic Acid

Denis, wazaka 25Rostov: “Aspirin yakhala mankhwala ofunika kwambiri kwa ine, nthawi zambiri, kugwa ndimakonda kugwira chimfine ndikugwiritsa ntchito ngati antipyretic komanso anti-kutupa. Sindikumvanso kuti mankhwala ali ndi vuto lililonse. ”

Irina Fedorovna, wazaka 43, Ryazan: "Acetylka ndi mankhwala akale, otsimikiziridwa, nthawi zonse amakhala mu nduna yanga yamankhwala. Nditangomva kuti ndikudwala, ndimachita monga abambo anga: ndimamwa mapiritsi awiri usiku ndi m'mawa bwino komanso zatsopano. "

Natalia, wazaka 30, Tula: “Mankhwalawa ndi achikale, kangapo konse komwe amathandizira ndi chimfine! Agogo anga amamwa ndi kupweteka minofu ndi mafinya, akuti, amathandiza. Chokhacho ndikuti sichitha kugwiritsidwa ntchito ndi amayi oyembekezera mu 1 ndi 3 trimesters, komanso nthawi yakusamba. Masks ofunikira a Aspirin amayeretsa ndi kupewetsa khungu. ”

Aspirin ndi kapangidwe kake

Malinga ndi gulu lomwe ambiri amavomereza, Aspirin amatchulidwa kuti ndi anti-kutupa, analgesic wothandizila wambiri. Kuphatikiza pa kuchitapo kanthu pazopweteka, mankhwalawa amagwiritsidwa ntchito kupewa mtima.

Mitundu yotulutsidwa ya Aspirin ndiyosiyanasiyana. Mankhwalawa amapezeka mu mawonekedwe a sungunuka komanso mapiritsi wamba. Mosasamala za mtundu wa kumasulidwa, gawo lalikulu la Aspirin ndi acetylsalicylic acid, lomwe limayang'anira gawo lalikulu la mankhwala.

Kamodzi m'thupi, chophatikizika chimakonzedwa kwathunthu kuchokera m'mimba. Chifukwa cha ntchito ya chiwindi komanso ma enzymes ake, asidi acetylsalicylic amasinthidwa kukhala metabolite yayikulu. Ndi zomwe amachita zomwe zimathandizira kuchepetsa kutentha kapena kuchepetsa ululu. Ndi ntchito yolumikizidwa ya chamoyo chonse, chinthucho chimachotsedwa kwathunthu pasanathe masiku atatu.

Mu pharmacology yamakono, acetylsalicylic acid imapezeka ndi kulumikizana kwa salicylic ndi asidi a sulfure ndi acetic anhydride. Ma makhiristo omwe amakhazikitsidwa amasakanizidwa ndi wowuma ndikupeza mankhwala odziwika bwino.

Zotsatira za pharmacological

Mankhwalawa amathandizanso kupweteka, kutentha komanso kutupazimasokoneza kusokonekera.

Gulu la pharmacological: NSAIDs.

Pharmacodynamics ndi pharmacokinetics

Acetylsalicylic acid - ndi chiyani?

Acetylsalicylic acid ndi salicylic ester wa acetic (ethanoic) acid.

Njira zamitundu ya acetylsalicylic acid ndi (ASA) - C₉H₈O₄.

Khodi ya OKPD 24.42.13.142 (acetylsalicylic acid wothira mankhwala ena).

Kupeza ASA

Popanga ASA, njira yodziyimira ndi ethanoic acid imagwiritsidwa ntchito.

Mankhwala

Mphamvu ya analgesic imachitika chifukwa cha zonse zapakati komanso zotumphukira. Ngati zotupa zachepa, zimachepetsa kutentha poyenda pamalo opatsirana kutentha.

Pharmacokinetics

Pafupifupi 80% ya dziko lomangidwa acetylsalicylic ndi salicylic acid. Ntchito yachilengedwe imapitilira ngakhale chinthucho chikakhala kuti chili m'mapuloteni.

Wopangidwira m'chiwindi. Amachotsa impso. Kutupa kumakhudzidwa ndi mkodzo pH: akaphatikizika, amachepetsa, ndipo akamera, amakula.

Magawo a Pharmacokinetic zimatengera kukula kwa mlingo womwe umamwa. Kuthetsa kwa thupilo sikuwonekera. Komanso, mu ana a 1 chaka cha moyo, poyerekeza ndi achikulire, amayamba pang'onopang'ono.

Zizindikiro zamagwiritsidwe: chifukwa chiyani mapiritsi a acetylsalicylic acid amathandiza?

Zisonyezo zakugwiritsa ntchito acetylsalicylic acid ndi:

matenda febrile matenda opatsirana ndi yotupa,
nyamakazi,
rheumatism,
zotupa zotupa myocardiumchifukwa cha immunopathological reaction,
ululu ochokera kumayendedwe osiyanasiyana, kuphatikiza kupweteka kwa dzino (kuphatikiza mutu wokhudzana ndi vuto lochotsa mowa), kupweteka kwa minofu ndi minyewa, neuralgia, migraines,nseru.

Komanso Asipirin (kapena acetylsalicylic acid) imagwiritsidwa ntchito ngati prophylactic ngati ikuwopseza thrombosis,thromboembolism, MI (pamene mankhwalawa amalembera kupewa kwachiwiri).

Contraindication

Kulandila ASA ndikotsutsana mu:

Mphumu,
pa kuchuluka zotupa ndi zotupa zodyera kumimba,
magazi am'mimba / m'mimba,
kusowa kwa Vitamini K,
hemophilia, hypoprothrombinemia, hemorrhagic diathesis,
Kuperewera kwa G6PD,
matenda oopsa a portal,
Kulephera kwa impso / chiwindi
mawa
munthawi yamankhwala (ngati mlingo wa sabata umaposa 15 / mg),
gouty nyamakazi, gout,
(miyezi itatu yoyambilira ndi itatu ndiyotsutsana kotheratu),
Hypersensitivity kwa ASA / salicylates.

Zotsatira zoyipa

Zotsatira zoyipa za mankhwala a ASA zimatha kuchitika motere:

Pogwiritsa ntchito nthawi yayitali, tinnitus imawoneka, kuchepa kwa makutu kumachepa, kupenya kwam'maso kumayipa, chizungulire chimachitika ndipo, ndimalo waukulu, mutu. Kuyamwa ndikothekanso. chisangalalokusanza bronchospasm.

Acetylsalicylic acid, malangizo (Njira ndi Mlingo)

At rheumatism yogwira Akuluakulu odwala amapatsidwa 5 mpaka 8 g ya ASA patsiku. Kwa mwana, mlingo umawerengeredwa kutengera kulemera. Monga lamulo, zimasiyana kuchokera pa 100 mpaka 125 mg / kg / tsiku. Kuchulukana kwa ntchito - 4-5 p.

Masabata 1-2 atatha maphunzirowa, mlingo wa mwanayo umachepetsedwa mpaka 60-70 mg / kg / tsiku, kwa odwala akuluakulu, mlingo umakhala womwewo. Pitilizani mankhwala ayenera kupitilira masabata 6.

Malinga ndi malangizo ogwiritsira ntchito acetylsalicylic acid, mankhwalawa ayenera kusiyidwa pang'onopang'ono kwa milungu iwiri.

Acetylsalicylic acid wothandizira pamutu komanso ngati njira yothetsera kutentha imayikidwa pakadontho kotsika. Chifukwa chake, ndi ululu ndi machitidwe Mlingo wa 1 mlingo wa munthu wamkulu - kuchokera 025 mpaka 1 g ndi kuchuluka kwa ntchito kuchokera ku 4 mpaka 6 ma ruble patsiku.

Tiyenera kukumbukira kuti ngati mutu ulibe mutu, ASA imakhala yothandiza kwambiri ngati ululuwu ukukwiya chifukwa cha kuchuluka kwa ICP (intracranial anzawo).

Kwa ana, mlingo woyenera kwambiri nthawi ndi 10-15 mg / kg. Kuchulukana kwa ntchito - 5 tsa / Tsiku.

Kuchiza sikuyenera kupitilira milungu iwiri.

Pochenjeza thrombosis ndi embolism ASA kutenga 2-3 tsa / tsiku. 0,5 g iliyonse.Kukonzanso zinthu zamatsenga (kwa kuchepetsedwa), mankhwalawa amatengedwa nthawi yayitali pa 0,15-0.25 g / tsiku.

Kwa mwana wamkulu wazaka zisanu, mlingo umodzi ndi 0,25 g, ana azaka zinayi amaloledwa kupereka 0,2 g ya ASA kamodzi, ana azaka ziwiri - 0,1 g, ndi wazaka chimodzi - 0,05 g.

Sizoletsedwa kupatsa ana kwa ASA kuchokera ku kutentha komwe kumakweza kumbuyo kachilombo. Mankhwalawa amagwira ntchito pa ubongo womwewo ndi chiwindi monga ma virus ena, komanso kachilombo zimapangitsa mwana kukulaMatenda a Reye.

Kugwiritsa ntchito ASA mu cosmetology

Acetylsalicylic acid chigoba chakumaso chimakupatsani mwayi kuti muchotse kutupa, muchepetse kutupa, chotsani redness, chotsani masanjidwe akufa a maselo akufa ndi ma pores oyera.

Acetylsalicylic acid kuchokera ziphuphu imagwira ntchito bwino limodzi ndi mandimu kapena uchi.Yothandiza kuthetsa mavuto a khungu ndi chigoba ndi dongo.

Chigoba chokhala ndi uchi chimakonzedwa motere: mapiritsi (zidutswa zitatu) amasungunuka ndi madzi, kenako, ndikasungunuka, osakanizidwa ndi supuni ya tiyi ya 0,5-1.

Kuti akonze dongo, mapiritsi 6 ofinidwa a ASA ndi supuni ziwiri (supuni) za dongo loyera / buluu ziyenera kusakanikirana ndi madzi ofunda.

Bongo

Mankhwala osokoneza bongo atha kuchokera ku:

chithandizo chautali cha ASA,
limodzi makonzedwe a mankhwala okwanira.

Chizindikiro cha bongo ndi salicylism syndrome, yowonetsedwa ndi malaise, hyperthermia, tinnitus, nseru, kusanza.

Olimba limodzi spasms, kusokonekera, kuchepa mphamvu kwa madzi, mapapu osakhala a cardiogenic, kuphwanya kwa CBS, kudabwitsa.

Ngati odwala a ASA ali ndi vuto lalikulu, wozunzidwayo ayenera kugonekedwa kuchipatala msanga. Mimba yake imatsukidwa, kupatsidwa, kufufuzidwa ndi CBS.

Kutengera momwe WWTP ilili komanso kuchuluka kwa madzi ndi ma elekitirodi, kuyambitsa mayankho kungapangidwe, sodium citrate ndi sodium bicarbonate (monga kulowetsedwa).

Ngati mkodzo pH ndi 7.5-8.0, ndipo kuchuluka kwa madzi am'magazi opitilira 300 mg / l (mwa mwana) ndi 500 mg / l (mwa munthu wamkulu), chisamaliro chofunikira chimafunikira zamchere zamchere.

Ndi kuledzera kwambiri kuchitidwa, kubwezeretsa madzi am'madzi, kupereka mankhwala.

Kuchita

Kupititsa patsogolo kuopsa kukonzekera kwa barbiturate,valproic acid, methotrexateZotsatira zamankhwala otulutsa pakamwa, zamwano, mankhwala a sulfa.

Zofooka okodzetsa (potaziyamu-wotaya ndi kutulutsa kwina), antihypertensive mankhwala ACE zoletsauricosuric othandizira.

Ndi munthawi yomweyo kugwiritsa ntchito mankhwala antithrombotic, manga,anticoagulants kumawonjezera mwayi wokhetsa magazi.

GCS imathandizira poizoni wa ASA pa mucous nembanemba wamimba m'mimba, kuwonjezera kukula kwake ndikuchepetsa ndende ya plasma.

Ikagwiritsidwa ntchito nthawi yomweyo ndi mchere, Li imakulitsa kuchuluka kwa plasma ya Li + ions.

Imapititsa patsogolo poledzera wama mowa pakhungu la m'mimba m'mimba.

Malonda ogulitsa

Zogulitsa za OTC.

Chinsinsi mu Latin (chitsanzo):

Rp: Acidi acetylsalicylici 0,5
D. t. d. N 10 mu tabu.
S. 1 piritsi 3 r. / Tsiku litatha kudya, kumwa madzi ambiri.

Malo osungira

Mapiritsi amayenera kusungidwa m'malo owuma pamtunda wotsika ndi 25 ° C.

Tsiku lotha ntchito

Malangizo apadera

Ngakhale muyezo yaying'ono, ASA imachepetsa kuchulukitsa. uric acidkuti odwala omwe atengeke mosavuta amatha kuyambitsa kuwopsa gout.

Mukamamwa mankhwala ochuluka a ASA kapena kufunika kwa chithandizo chanthawi yayitali ndi mankhwalawa, ndikofunikira kuwunika pafupipafupi msanga dokotala.

Monga othandizira-kutupa, kugwiritsa ntchito ASA muyezo wa 5-8 g / tsiku. ochepa chifukwa chowonjezeka chiopsezo chotsatira cham'mimba.

Kuchepetsa magazi munthawi ya opareshoni komanso munthawi ya kugwira ntchito, kutenga salicylates kumaimitsidwa masiku 5-7 musanachite opareshoni.

Mukamamwa ASA, muyenera kukumbukira kuti mankhwalawa amatha kumwa kwa masiku osaposera 7 popanda kufunsa dokotala. Monga antipyretic ASA, amaloledwa kumwa osaposa masiku atatu.

Mankhwala okhala ndi chinthu

Thupi lomwe limapangidwa ndi mawonekedwe oyera ndi ufa wa makristalo oyera. Maonekedwe akununkhira amchere acetic ndikuwonetsa kuti chinthucho chimayamba hydrolyze.

kachilombo , popeza kuphatikiza koteroko kumatha kuyambitsa mkhalidwe wowopsa wa mwana - Matenda a Reye.

Mwa makanda, salicylic acid imatha kulowa m'malo chifukwa albin bilirubin ndi olimbikitsa chitukuko encephalopathy.

ASA imalowa mosavuta m'madzi onse amthupi ndi zimakhala, kuphatikiza zamadzimadzi, zotumphukira ndi peritoneal fluid.

Pamaso pa edema ndi kutupa, kulowa kwa salicylate kulowa kolumikizira kwamkati kumathandizira. Mu siteji ya kutupa, m'malo mwake, imachepera.

Acetylsalicylic acid ndi mowa

Mowa pa nthawi ya ASA ndiwotsutsana. Kuphatikizikaku kungayambitse magazi am'mimba komanso m'matumbo, komanso kupweteka kwakukulu kwa hypersensitivity.

Kodi acetylsalicylic acid wa hangover ndi chiyani?

ASA ndiwothandiza kwambiri kwa hangover, chifukwa cha antiplatelet zotsatira za mankhwala.

Komabe, muyenera kukumbukira kuti kumwa mapiritsi ndibwino kuti musamwe mowa, koma pafupifupi maola awiri phwando lisanachitike. Izi zimachepetsa chiopsezo cha maphunziro. micothrombi zing'onozing'ono zaubongo ndipo - gawo - minofu edema.

Gwiritsani ntchito panthawi yoyembekezera komanso poyamwitsa

ASA ndi ma metabolites ang'onoang'ono amalowera mkaka. Pambuyo popereka mankhwala mwangozi, mavuto sanawonedwe mwa makanda, chifukwa chake, monga lamulo, kusokonezeka kwa kuyamwitsa sikofunikira.

Ngati mayi akuwonetsedwa chithandizo chamanthawi yayitali ndi ASA yayikulu, ndikofunikira kuti muchepetse chiwindi B.

Malangizo ogwiritsira ntchito:

Acetylsalicylic acid ndi mankhwala omwe amatchulidwa odana ndi kutupa, antipyretic, analgesic ndi antiaggregant (amachepetsa kuphatikiza kupatsidwa zinthu za m'magazi).

Zotsatira za pharmacological

Limagwirira ntchito acetylsalicylic acid ndi chifukwa amatha kuletsa kapangidwe ka prostaglandins, omwe amathandiza kwambiri pakupanga njira zotupa, kutentha thupi ndi kupweteka.

Kuchepa kwa chiwerengero cha ma prostaglandins pakatikati pa thermoregulation kumabweretsa vasodilation ndi kuwonjezeka kwa thukuta, komwe kumayambitsa antipyretic mphamvu ya mankhwalawa. Kuphatikiza apo, kugwiritsa ntchito acetylsalicylic acid kungachepetse chidwi cha kutsika kwa mitsempha kwa opweteketsa mtima mwakuchepetsa mphamvu ya ma prostaglandins pa iwo. Mukamamwa, kuchuluka kwambiri kwa acetylsalicylic acid m'magazi kumatha kuwonedwa pambuyo pa mphindi 10-20, ndikupanga chifukwa cha metabolic ya salicylate pambuyo pa maola 0.3-2. Acetylsalicylic acid imachotsedwa kudzera mu impso, theka la moyo ndi mphindi 20, theka la moyo wa salicylate ndi maola 2.

Zisonyezo zogwiritsa ntchito acetylsalicylic acid

Acetylsalicylic acid, zomwe zikuwonetsa chifukwa cha katundu wake, zalembedwa kuti:

pachimake rheumatic fever, pericarditis (kutukusira kwa membrane wamkati wamtima), nyamakazi yodutsitsa (kuwonongeka kwa minyewa yolumikizana ndi ziwiya zazing'ono), chorea chorea (chowonetsedwa ndi contractions ya minyewa yosadzipereka), kavalidwe ka Dressler (kuphatikiza kwa pericarditis ndi kutupa kwa pleural kapena chibayo),
ululu wammbuyo yofatsa kwambiri pakati: migraine, mutu, mano, kupweteka msambo, matenda am'mimba, neuralgia, kupweteka kwa mafupa, minofu,
Matenda a msana limodzi ndi ululu: sciatica, lumbago, osteochondrosis,
febrile syndrome
kufunika kwa kulolerana ndi mankhwala omwe amaletsa kutupa kwa odwala omwe ali ndi "aspirin triad" (kuphatikiza mphumu ya bronchial, polyps ndi kusalolerana kwa acetylsalicylic acid) kapena "asipirin",
kupewa myocardial infarction mu mitima matenda kapena kupewa kuyambiranso,
Kukhalapo kwa zinthu zomwe zingayambitse vuto losawonongeka, matenda a mtima, matenda osakhazikika,
prophylaxis ya thromboembolism (chotchinga chotengera ndi thrombus), mitral valavu yovunda pamtima, mitral valve prolapse (kukomoka), michere yotupa (kutayika kwa mphamvu ya minofu ya atria kuti igwiritse ntchito molumikizana),
pachimake thrombophlebitis (kutupa kwa khoma la mitsempha ndi mapangidwe a thrombus kutsekereza lumen mkati mwake), pulmonary infarction (kutsekeka kwa chotchinga chotengera chopatsa mapapo).

Malangizo ogwiritsira ntchito acetylsalicylic acid

Mapiritsi a acetylsalicylic acid adapangira kuti azigwiritsidwa ntchito pakamwa, tikulimbikitsidwa kuti muzidya pambuyo pakudya ndi mkaka, madzi abwinobwino kapena mchere wamchere.

Akuluakulu, acetylsalicylic acid akulimbikitsidwa kugwiritsa ntchito mapiritsi a 3-4 patsiku, mapiritsi a 1-2 (500-1000 mg), okhala ndi mapiritsi a 6 tsiku lililonse (3 g). Kutalika kwakukulu kogwiritsa ntchito acetylsalicylic acid ndi masiku 14.

Pofuna kukonza zofunikira za magazi, komanso choletsa kuphatikizika kwa mapulateleti, piritsi la acetylsalicylic acid patsiku limayikidwa miyezi ingapo. Ndi myocardial infarction komanso kupewa sekondale yotupa, malangizo a acetylsalicylic acid amalimbikitsa kumwa 250 mg patsiku. Mphamvu yamphamvu ya cerebrovascular and ubongo wa thromboembolism imalimbikitsa kutenga piritsi la ety acetylsalicylic acid ndikusintha pang'onopang'ono kwa mapiritsi ku mapiritsi awiri patsiku.

Acetylsalicylic acid amalembedwa kwa ana mwanjira imodzi: wamkulu kuposa zaka 2 - 100 mg, zaka 3 za moyo - 150 mg, wazaka zinayi - 200 mg, wamkulu kuposa zaka 5 - 250 mg. Ndikulimbikitsidwa kuti ana atenge acetylsalicylic acid katatu patsiku.

Zofanana za Aspirin ndi Acetylsalicylic Acid Mapangidwe

Chosakaniza chophatikizika mu kukonzekera konseku ndi acetylsalicylic acid (salicylic acetic acid ester) pa mlingo wa 500 mg / 1 tabu. Malinga ndi mankhwala a pharmacological, amadziwika kuti ndi zinthu zopanda mankhwala monga anti -idalidal.

Zochita za mankhwalawa zimakhazikitsidwa ndizomwe zimapangitsa panthawi imodzi mitundu iwiri ya cycloo oxygenase (mitundu 1 ndi 2). Kuchepa kwa kutentha kwa thupi ndi mpumulo wa zowawa (zolumikizana, minofu ndi mutu) ngati zovuta za thupi zimagwirizanitsidwa ndi kuphatikizika kwa kapangidwe ka COX-2. COX-1 imakhudzidwa ndikupanga ma prostaglandins, chifukwa chake, kuponderezedwa kwa kaphatikizidwe kake kumayambitsa zovuta zomwe zimakhudzana ndi kuwonongeka kwa minofu ya cytoprotection. Koma nthawi yomweyo acetylsalicylic acid amalepheretsa kaphatikizidwe ka thromboo oxygenase.

Chizindikiro chakugwiritsa ntchito kwa Aspirin (kapena ASA) ndikupewa wa thrombosis ndi embolism, momwe amachepetsa chiopsezo cha myocardial infarction ndi ischemic stroke.

Kubwezeretsanso mkhalidwe wa odwala omwe ali ndi mitsempha ya varicose mutatenga ASA kumachitikanso mogwirizana ndi kuletsa kwa kaphatikizidwe ka thromboxanes ndi kuchotsedwa kwa chimodzi mwazomwe zimayambitsa kukulitsa kwamitsempha - kukula kwa magazi (kukulitsa kukhuthala kwake komanso chizolowezi chopanga magazi).

Mlingo wa mankhwala

Lamulo loti mutenge Aspirin ndi acetylsalicylic acid ndilofanana ndipo zimatengera chisonyezo chachikulu chogwiritsa ntchito, komanso mikhalidwe yaumoyo wa anthu. Katswiri aliyense angatsimikizire kuti mulingo wa mankhwalawa ndiwopadera payekha.Komabe, munkhwala ndimakonda kugwiritsa ntchito njira zingapo:

Kuti athetse ululu wammbuyo mwa munthu wamkulu (woposa zaka 15), piritsi limodzi (500 kapena 1000 mg) limagwiritsidwa ntchito. The pakati pakati Mlingo ayenera kukhala osachepera 4 maola, ndipo maphunzirowo amatenga osaposa masiku 5.
Ngati munthu akufunika kuchepetsa malungo, ndiye kuti mankhwalawa amalembedwa mpaka masiku atatu. Kuti mukwaniritse zomwe mukufuna, mankhwalawa amatsukidwa ndi madzi ambiri.
Poletsa mtima ndi matenda a mtima, piritsi limodzi limayikidwa patsiku kapena tsiku lililonse. Kutalika kwa maphunzirowa kumatsimikiziridwa ndi dokotala wopita.

Madokotala amalimbikitsa kumwa mankhwalawa mukatha kudya. Izi zimapangitsa kuti chinthu chogwira ntchito chizikhala cholowa komanso chothandiza pakuchiritsa, popanda kuvulaza mucosa. Sikoyenera kupereka mankhwala kwa inu nokha;

Kuyerekezera Mankhwala

Aspirin kapena acetylsalicylic acid, ndibwino bwanji? Sizingatheke kupeza yankho lenileni la funso ili. Mwakutero, mankhwalawa amasiyana kokha mwa mtundu wa kumasulidwa ndi mlingo wa chinthu chachikulu chogwira ntchito.

Mankhwalawa ndi ofanana pakapangidwe, chizindikiritso cha Aspirin ndi acetylsalicylic acid ndichinthu chomwecho, chomwe chimapangitsa kuti mankhwalawa asinthane. Kusiyanitsa kwakukulu pakati pa mankhwalawo ndi mtengo, zomwe zimatengera wopanga, kuchuluka kwa asidi piritsi ndi mawonekedwe a kumasulidwa. Acetylsalicylic acid, monga lamulo, amagulitsidwa pang'ono mtengo kuposa Aspirin ofanana.

Ngati munthu samvera zigawo za Aspirin, ndiye kuti kumwa acetylsalicylic acid kumapangidwanso kwa iye. Komabe, pharmacology yamakono imakhala ndi mitundu yambiri ya mitundu, yomwe m'malo mwake imatha kusintha salicylic acid.

Ma Analogs a "Aspirin" ndi acetylsalicylic acid:

Chuma
"Paracetamol".
"Egithromb" (wopambana kwambiri pamafanizo ena pamtengo).
Movalis (ofanana pamtengo kupita ku Egithromb).

Pafupifupi, mtengo wa Aspirin umasiyana kuchokera ku ma ruble 70 mpaka ma ruble 500.

Zowonjezera zosangalatsa

Akatswiri amalimbikitsa kutsatira malamulo ena omwe amateteza thupi momwe angathere, popanda kuchepetsa kugwiritsa ntchito mankhwalawa:

Ngati phale laphwanyidwapo, ndiye kuti zochita zake zidzafulumira.
Ndikofunika kuteteza mucosa wam'mimba ku zochita za acetylsalicylic acid. Piritsi imatengedwa pokhapokha chakudya.
Kumbukirani kuwonjezera kuchuluka kwa magazi, komwe kumachepetsa kugwiritsa ntchito Aspirin musanachite opareshoni, ngakhale musanapite kwa dokotala wamano. Mankhwalawa amalekanitsidwa osagwiritsidwa ntchito sabata limodzi asanachite opareshoni.
Mankhwala amachepetsa kuchulukitsidwa kwa uric acid, ofunikanso kuganizira ndi thanzi lanu.

Kutsatira moyenera malangizo a dokotala kumathandiza kupewa njira zosafunikira m'thupi, popanda kuchepetsa kugwiritsa ntchito bwino mankhwala.

Zowonjezera

Malinga ndi malangizowo, acetylsalicylic acid sungasungidwe m'malo omwe kutentha kwa mpweya kumatha kukwera pamwamba pa 25 ° C. Pamalo owuma komanso kutentha kwa firiji, mankhwalawa adzakhala oyenera zaka 4.

Mankhwala odziwika kwambiri, a aspirin, adatchuka chifukwa chogwira ntchito pakampani yopanga mankhwala a Bayer, omwe mu 1893 adapanga ukadaulo wopangira mankhwalawa. Dzina lamalonda "Aspirin" lidapangidwa pamaziko a kalata "A" (acetyl) ndi "Spiraea" - mayina a chomera cha meadowsweet ku Latin. Mankhwala othandizira, acetylsalicylic acid, adayamba kupatulidwa kuchokera pachomera ichi.

Mankhwala otchuka kwambiri, aspirin, atchuka kwambiri pakampani yopanga mankhwala ya Bayer.

Katundu wa Aspirin

Mankhwala, makungwa a msondodzi anali wotchuka ngati chida chothandiza chomwe chimathandizira kutentha.Komabe, mankhwala omwe adakhazikikapo adadzetsa zotsatirapo zosasangalatsa, zomwe adadziwonetsa mu mseru komanso kupweteka kosaletseka pamimba.

Acetylsalicylic acid (ASA) - dzina lina la Aspirin - idapezedwa koyamba kuchokera ku bark ya msondodzi koyambirira kwa zaka za m'ma 1900. Pofika pakati pa zaka zana zija, njira yokhala ndi mchere wa salicylic acid idapezeka. Kwa nthawi yoyamba, zitsanzo za ASK zomwe zimakhala zoyenera kugwiritsa ntchito zachipatala zinalandiridwa ndi ogwira ntchito ku Bayer. Kampaniyi idayamba kugulitsa mankhwalawo pansi pa dzina la Aspirin.

Pambuyo pake, makampani ena adakhalanso ndi ufulu wogulitsa mankhwalawo, omwe adalola kuti mankhwalawo afikire kumashelufu onse azamankhwala padziko lapansi.

Acetylsalicylic acid, kapena Acidum acetylsalicylicum (dzina lachi Latin lotchedwa Aspirin), anali yekhayo mankhwala panthawiyo omwe anali m'gulu la mankhwala omwe si a steroidal omwe ali ndi zotsutsana ndi kutupa. Mankhwalawa anali phindu lenileni la mankhwala. Ndi chithandizo chake, kuchuluka kwa omwe amwalira chifukwa cha malungo kunachepa kwambiri, ndipo atatha kuthana ndi magazi a Aspirin, anthu anapeza mwayi wokhala ndi moyo wabwinobwino atadwala matenda a mtima, matenda a sitiroko, ndi zina zambiri.

Acetylsalicylic acid (dzina lachiwiri ndi Aspirin) lilidi ndi katundu wapadera. Mu 70s, zidawululidwa kuti zimatha kupondereza zochitika za prostogladins. Chifukwa cha nyumbayi, Aspirin amachotsa zotupa chifukwa cha zomwe zimachitika panjira yake.

Mphamvu ya analgesic ndi kuchotsedwa kwa kutentha kumachitika chifukwa cha kusokonekera kwa madera aubongo omwe amachititsa kuti kuzindikiritsa kupweteka komanso kutulutsa kuziziritsa.

Chizindikiro chinanso chogwiritsa ntchito ndikuwonjezereka kwa nkhawa ndi kupweteka kwa m'mutu. Ndi makonzedwe apadera a Aspirin, zakumwa zamagazi, ndi mipata m'matumbo zimakulanso, zomwe zimalepheretsa kukula kwa mtima, stroko kwa odwala omwe ali ndi chizolowezi chopanga magazi.

Acetic acid salicylic ester (monga Aspirin amatchedwa mwanjira ina) amagwiritsidwa ntchito kwambiri tsiku ndi tsiku. Piritsi limodzi lidzachepetsa vutoli. Makamaka pa izi, muyenera kugula mankhwala a Alka-Seltzer kapena Aspirin UPSA (dzina lamankhwala a hangover, lomwe lili ndi acetylsalicylic acid).

Ndizofunikira kudziwa kuti, malinga ndi kafukufuku yemwe anachitika ku Oxford University, kugwiritsidwa ntchito mwadongosolo kwa Aspirin kumachepetsa chiopsezo chotenga ma oncology mu gland ya mammary, Prostate, esophagus, mapapu ndi mmero.

Acetylsalicylic acid (dzina la Aspirin) itha kugwiritsidwa ntchito palokha, kapena kuphatikiza ndi mankhwala ena. Masiku ano, pali ndalama zambiri momwe zimakhalira - Citramon, Askofen, Asfen, Coficil, Acelisin. Tengani mankhwalawa nokha komanso osakaniza ndi mankhwala ena.

Aspirin chifukwa cha chimfine

Aspirin, kapena acetylsalicylic acid, ndi mankhwala omwe amachepetsa msanga ululu wowopsa wazomwe zimachokera ndipo zimakhudza kuyipa kwa chidwi. Kuphatikiza pa zinthuzi, mankhwalawa amaperekedwa kwa magazi kuwonda kwambiri chifukwa anthu amakonda kuziluka m'magazi. Aspirin chifukwa cha chimfine chimagwiritsidwanso ntchito nthawi zambiri, chifukwa amatha kuthana ndi malungo, mwachangu kuchepetsa zisonyezo za kutentha.

Zomwe mlingo wa acetylsalicylic acid umayenera kugwiritsidwa ntchito pozizira, kodi pali zotsutsana pazomwe tikugwiritsa ntchito, timaphunziranso.

Mwapeza cholakwika? Sankhani ndikusindikiza Ctrl + Lowani

Kodi mankhwalawa "Aspirin"
Momwe mungamwere mapiritsi
Ndi mankhwalawa omwe angathe kumwa mankhwalawa
Kodi othandizira kukhetsa magazi

Thandizo la acid

Sikuti aliyense amadziwa kuti gawo lalikulu la mankhwalawa ndi salicylic acid, ochotsedwa mu chitsamba chapadera chotchedwa siprea, chomwe chimafotokoza kupezeka kwa dzina lodziwika bwino "Aspirin".Chofanana chomwechi chimapezekanso mmera zina zambiri, monga peyala, jasmine kapena msondodzi, womwe umagwiritsidwa ntchito mwachangu ku Egypt ndipo amafotokozedwa ngati mankhwala amphamvu ndi a Hippocrates okha.

Zochizira

Pambuyo pa kutenga acetylsalicylic acid mthupi, hyperemia imachepa, kuchuluka kwa ma capillaries kumalo otupa kumachepa - zonsezi zimayambitsa kuwonekera kwa analgesic komanso anti-kutupa. Mankhwalawa amalowa m'matumbo onse ndi madzi, kunyowa kumachitika m'matumbo ndi chiwindi.

Zochita za acetylsalicylic acid:

imakhala yolimbana ndi zotupa-m'masiku 24-48 atatha mankhwala,
amathetsa kupweteka pang'ono mpaka pang'ono,
Amachepetsa kutentha thupi, osakhudza kuchita bwino,
acetylsalicylic acid imachepetsa magazi, imasokoneza kuphatikiza kwa mapulateleti - katundu pa minofu yamtima imachepa, chiwopsezo cha matenda amtima chimachepa.

Mankhwalawa atha kuthandizidwa kuti muchepetse thrombosis, stroko, kuchepetsa chiopsezo cha kusokonezeka kwa magazi mu ubongo.

Tcherani khutu! Mphamvu ya antiplatelet ya ASA imawonedwa pakatha masiku 7 pambuyo pa kumwa kamodzi. Chifukwa chake, mankhwalawa sangathe kuledzera asana opaleshoni, posachedwa kusamba.

Amakonda kutenga acetylsalicylic acid zoletsa (ziletsa) mapangidwe a magazi (ziwunda za magazi), zomwe zitha kutsekereza lumen ya mtsempha wamagazi. Izi pafupifupi zimachepetsa chiopsezo cha matenda amtima.

Chifukwa cha zochitika zambiri, acetylsalicylic acid amagwiritsidwa ntchito pochiza komanso kupewa matenda osiyanasiyana obwera chifukwa cha ana ndi ana opitilira zaka 15.

Zomwe zimathandiza acetylsalicylic acid:

mavuto omwe amayendera limodzi ndi matenda opatsirana komanso otupa,
rheumatism, nyamakazi, pericarditis,
migraine, mano, minofu, kupweteka, msambo, neuralgia,
kupewa matenda amtima, kugwidwa ndi mavuto azungulire, kuchuluka kwamitsempha yamagazi,
kupewa magazi kuwundana ndi chibadwa cha thrombophlebitis,
angina pectoris.

ASAs imaphatikizidwa ndi zovuta kuchiza pneumonia, pleurisy, osteochondrosis, lumbago, zolakwika za mtima, mitral valve prolfall. Mankhwalawa amalimbikitsidwa kuti agwiritsidwe ntchito ngati zizindikiro zoyambirira za chimfine, chimfine chawoneka - zimathandizira thukuta, zomwe zimapangitsa kuti zinthu zikhale bwino.

Uphungu! Aspirin ndi imodzi mwamankhwala abwino kwambiri ochotsera vuto la hangover; mankhwalawa amachepetsa magazi, amachotsa mutu ndi kutupa, komanso amachepetsa kupanikizika kwa intracranial.

Acetylsalicylic acid wamutu wodziwika bwino umatchedwa aspirin kapena piritsi ya mutu. Ndi anti-yotupa komanso antipyretic.

Ndikotheka kutenga aspirin kwa amayi apakati komanso oyembekezera, ana

Acetylsalicylic acid amaswa ana osaposa zaka 14, popeza mankhwalawa amatha kuthamangitsa bilirubin, omwe angayambitse encephalopathy mu makanda, aimpso kwambiri ndi hepatic pathologies kwa ana asukulu zam'mbuyo komanso achinyamata. Mlingo wa ana ndi 250 mg kawiri patsiku, mlingo wovomerezeka tsiku lililonse ndi 750 mg.

Acetylsalicylic acid amaletsedwa kokhazikika panthawi yomwe mayi ali ndi nthawi yoyambirira - mankhwalawa ali ndi mphamvu ya teratogenic, angayambitse kukula kwa zolakwika za mtima wa mwana mwa ana, kugawanika kwa khansa yapamwamba.

Tcherani khutu! ASA nthawi zambiri imayambitsa kusokonezeka koyambirira.

N`zosatheka kutenga acetylsalicylic acid, paracetamol ngakhale mu 3 trimester - mankhwalawa amayambitsa matenda oopsa a pulmonary mu fetus, omwe amachititsa kukula kwa ma pathologies mu airways, magazi opatsika.Kugwiritsa ntchito ASA panthawiyi kungayambitse magazi kwambiri muchiberekero.

Mukamayamwa, simungatenge ASA, popeza asidi amalowa mkaka, omwe angayambitse thanzi labwino la mwana, kukula kwa mayankho amphamvu.

Mu mawonekedwe a trimester yachiwiri, kuvomerezedwa ndikotheka, koma pokhapokha ngati pali umboni wakuthwa komanso ndi chilolezo chodwala, kuvomerezedwa ndizosaloledwa panthawi yomaliza kubereka mwana

Malangizo ogwiritsira ntchito acetylsalicylic acid

ASA iyenera kumwedwa mutatha kudya, kuti musayambitse kuwonongeka m'matumbo, mutha kumwa ndi madzi opanda mpweya kapena mkaka. Mlingo wokhazikika ndi mapiritsi 1-2 pa 2 kawiri pa tsiku, koma osapitirira 1000 mg nthawi imodzi. Simungamwe mapiritsi oposa 6 patsiku.

Momwe mungatenge ASA pazinthu zina:

Kwa kuwonda kwa magazi, ngati prophylactic motsutsana ndi vuto la mtima - 250 mg tsiku lililonse kwa miyezi iwiri. Muzochitika zadzidzidzi, kuchuluka kwa mlingo wa mpaka 750 mg ndikuloledwa.
Acetylsalicylic acid kuchokera kumutu - ndikokwanira kumwa 250-500 mg wa ASA, ngati kuli kotheka, mutha kubwereza mlingo pambuyo maola 4-5.
Ndi chimfine, kuzizira, kutentha, mano - 500-1000 mg wa mankhwalawa maola 4 aliwonse, koma osaposa mapiritsi 6 patsiku.
Kuti muchepetse kupweteka msambo - kumwa 250-500 mg wa ASA, ngati ndi kotheka, bwerezani pambuyo pa maola 8-10.

Uphungu! Imwani Aspirin ndi kuwonjezeka pang'ono kwa magawo ochepa, ngati palibe mankhwala a antihypertensive omwe ali pafupi.

Mbiri pang'ono

Acetylsalicylic acid adapezeka koyamba kumapeto kwa zaka za m'ma 18 ndi Fris Hoffman, chemist wachichepere, yemwe panthawiyo ankagwira ntchito ku Bayer. Anafunitsitsadi kukhala ndi chida chomwe chithandiza bambo ake kuthetsa ululu wolumikizana. Lingaliro la komwe angayang'ane mawonekedwe omwe adafunikira, adalimbikitsidwa ndi adokotala a abambo ake. Adalamulira sodium salicylate kwa wodwala wake, koma wodwalayo sakanatha kutero, popeza anakwiya kwambiri m'mimba.

Pambuyo pazaka ziwiri, mankhwala ngati Aspirin adasindikiza ku Berlin, kotero acetylsalicylic acid ndi Aspirin. Awa ndi dzina lofupikitsidwa: prefix "a" ndi gulu la acetyl lomwe lalumikizidwa ndi salicylic acid, muzu "spir" umawonetsa spiric acid (mtundu uwu wa asidi umapezeka mwanjira ya ether muzomera, umodzi wawo ndi spirea), ndipo mathero ndi "mu" masiku amenewo, omwe amagwiritsidwa ntchito ngati mayina a mankhwala.

Aspirin: mankhwala

Amapezeka kuti acetylsalicylic acid ndi Aspirin, ndipo molekyulu yake imakhala ndi asidi awiri omwe amagwira ntchito: ma salicylic ndi acetic. Ngati mumasunga mankhwalawo firiji, ndiye kuti pamakhala chinyezi chambiri chimasokonekera mosavuta m'magulu awiri a asidi.

Ichi ndichifukwa chake kapangidwe ka "Aspirin" nthawi zonse kamakhala ndi ma acetic ndi salicylic acid, patapita nthawi yochepa gawo lalikulu limakhala laling'ono. Alumali moyo wa mankhwalawa zimatengera izi.

Kumwa mapiritsi

Aspirin atalowa m'mimba, kenako mpaka mu duodenum, madzi ochokera m'mimba sachitapo kanthu chifukwa mankhwalawo amasungunuka bwino kwambiri. Pambuyo pa duodenum, imalowetsedwa m'magazi, ndipo pokhapokha pakusintha kwake, salicylic acid imamasulidwa. Pomwe thupilo limafikira m'chiwindi, kuchuluka kwa ma asidi amachepetsa, koma zotumphukira zawo zam'madzi zimakhala zochulukirapo.

Ndipo akudutsa ziwiya za thupi, amafika impso, pomwe amapakidwa ndi mkodzo. Kutulutsa kwa Aspirin kumatsalira mlingo wochepa - 0,5%, ndipo ndalama zotsalazo ndi metabolites. Ndi omwe ali omwe achire popanga mankhwala. Ndikufunanso kunena kuti mankhwalawa ali ndi zotsatira 4 zochizira:

Kupewa kwa magazi.
Anti-yotupa katundu.
Antipyretic zotsatira.
Kumvera ululu.

Acetylsalicylic acid ili ndi gawo lalikulu, malangizowa ali ndi malingaliro atsatanetsatane ogwiritsira ntchito. Onetsetsani kuti mumazolowera kapena kuonana ndi dokotala.

Aspirin: ntchito

Tidazindikira momwe acetylsalicylic acid amagwira ntchito. Kuchokera pazomwe amathandizazi, tidzamvetsetsa.

Lemberani ululu.
Kutentha kwambiri.
Ndi mitundu yosiyanasiyana yotupa.
Mankhwalawa komanso kupewa rheumatism.
Kwa kupewa thrombosis.
Kupewa kugwidwa ndi matenda a mtima.

Mankhwala abwino kwambiri ndi acetylsalicylic acid, mtengo wake udzasangalatsanso aliyense, chifukwa ndiwotsika komanso umasinthasintha mkati mwa ma ruble kutengera wopanga ndi kipimo.

Aspirin: nkhondo yolimbana ndi magazi

Mapazi a magazi amapezeka m'malo amitsempha yamagazi komwe kumapangitsa kuwonongeka kwa makoma. M'malo awa, ulusi umakhala wowonekera womwe umamangiriza maselo wina ndi mnzake. Mitsempha yamagazi imachedwetsedwa pa iwo, yomwe imapangitsa chinthu chomwe chimathandizira kumamatira, ndipo m'malo oterowo chotchinga chimasweka.

Nthawi zambiri, mthupi lathanzi, thromboxane imatsutsidwa ndi chinthu china - uhule, silimalola kuti maselo a magazi aphatikizane ndipo, motsutsana, amachepetsa mitsempha yamagazi. Panthawi yomwe chotengera chiwonongeka, mphamvu pakati pazinthu ziwirizi zimasuntha, ndipo uhule umangopanga. Thromboxane imapangidwa mopitirira muyeso, ndipo chovala chamapulogalamu chimakula. Chifukwa chake, magazi amayenda m'madzi tsiku lililonse pang'onopang'ono. Mtsogolomo, izi zimatha kudzetsa matenda a stroke kapena kugunda kwa mtima. Ngati acetylsalicylic acid amatengedwa nthawi zonse (mtengo wa mankhwalawo, monga momwe taonera kale, ndiwotsika mtengo), ndiye kuti zonse zimasintha kwambiri.

Ma acids omwe amapanga Aspirin amalepheretsa kukula kwa thromboxane komanso amathandizira kuchotsa mthupi. Chifukwa chake, mankhwalawa amateteza mitsempha yamagazi m'magazi, koma zimatenga pafupifupi masiku 10 kuti amwe mankhwalawo, chifukwa pokhapokha ngati mapepalawa apezanso mphamvu yokumamatira.

"Aspirin" monga wotsutsa-yotupa ndi painkiller

Mankhwalawa amasokonezeranso njira yotupa yomwe imayendetsa thupi, imalepheretsa kutuluka kwa magazi kupita kumalo otupa, komanso zinthu zomwe zimapangitsa kupweteka. Ali ndi kuthekera kokuthandizira kupanga kwa histamine ya histamine, yomwe imachepetsa mitsempha yamagazi ndikuwonjezera kutuluka kwa magazi kupita ku malo othandizira. Zimathandizanso kulimbitsa makoma a zotengera zoonda. Zonsezi zimapangitsa anti-yotupa komanso analgesic kwenikweni.

Monga momwe tidadziwira, asidi acetylsalicylic amathandiza polimbana ndi kutentha. Komabe, uwu si mwayi wake wokhawo. Imagwira mu mitundu yonse ya kutupa ndi kupweteka komwe kumachitika mthupi la munthu. Ichi ndichifukwa chake mankhwalawa amapezeka kwambiri m'matumba a mankhwala apakhomo.

"Aspirin" wa ana

Acetylsalicylic acid amalembera ana pamawonekedwe otentha, matenda opatsirana komanso otupa komanso kupweteka kwambiri. Tengani mosamala ndi ana osakwana zaka 14. Koma kwa iwo omwe afika pa tsiku la 14, mutha kutenga theka la piritsi (250 mg) m'mawa ndi madzulo.

"Aspirin" amatengedwa mukatha kudya, ndipo ana ayenera kupera piritsi ndi kumwa madzi ambiri.

Pomaliza

Chifukwa chake mwachidule. Kodi chimathandiza acetylsalicylic acid ndi chiyani? Mankhwalawa amathandizira polimbana ndi malungo, magazi kuwundana, ndiwothandiza kwambiri kutsutsana ndi zotupa komanso pakhungu.

Ngakhale kuti mankhwalawa ali ndi zotsutsana zazikulu kwambiri kuti agwiritse ntchito, amalonjeza tsogolo labwino. Pakadali pano, asayansi ambiri akuyang'ana zowonjezera izi zomwe zingachepetse kuwonongeka kwa mankhwalawa pazinthu zina. Amakhulupiriranso kuti mankhwala ena sangathe kuthamangitsa Aspirin, koma, m'malo mwake, azitha kugwiritsa ntchito zatsopano.

Aspirin ndi bwenzi lowopsa koma lokhulupirika

Mwina, mutafunsa aliyense wa ife kuti atchuleni mankhwala odziwika bwino, aliyense adzakumbukira mankhwala omwewo. Piritsi lodabwitsa ili muubwana latipulumutsa ife ku matenda otentha kwambiri, ndipo ana okhwima kale akumuthokoza chifukwa chobwezeretsa moyo m'mawa - m'mawa, pambuyo paphwando ndi kumwa kwina kosafunikira. Anthu ena amadziwa kuti kwa anthu achikulire, madokotala nthawi zambiri amapereka mankhwala awa - ochepa Mlingo, koma tsiku lililonse. Kodi pali ntchito zambiri kwambiri pa kobiri limodzi ndi mtengo wotsika mtengo?

Ndipo kuchiritsa kwodabwitsaku kumakhalanso ndi dzina loyipa - akuti lingayambitse kupweteka m'mimba, ndipo sikuloledwa kwa ana kuti aperekenso. Aliyense amakumbukira zotsatsa pa TV - za mapiritsi a effeedcent, omwe amati ndi abwino kuposa masiku onse, koma akukhulupirira kuti kuchokera kwa iwo ndikuti palinso zowonongeka zina.

Kodi ndi mtundu wanji wa mankhwalawa? Zachidziwikire, aspirin.

Katundu wa Aspirin

Kodi mapiritsi amodzi amodzi angathandize bwanji nthawi imodzi ndi matenda opatsirana, rheumatism, migraines ndi matenda amtima?

Acetylsalicylic acid ilidi ndi katundu wapadera. Imatha kuletsa ntchito ya ma cycloo oxygenase enzymes (COX-1, COX-2, etc.), yomwe imayang'anira kapangidwe ka oyimira pakati otupa - ma prostaglandins. Chifukwa cha machitidwe a aspirin, mphamvu yamphamvu yotupa imachepa, yomwe imatsogolera pakufika kwake. Izi ndizofunikira makamaka poti kutupa kumakhala kovulaza thupi - mwachitsanzo, ndi matenda amitsempha.

Zotsatira za antipyretic ndi analgesic za aspirin zimagwirizanitsidwa ndi kukhumudwitsa komwe kumayambitsa magawo a ubongo, omwe amachititsa kuti akatswiri azindikire komanso azindikire kupweteka. Chifukwa chake, pakatentha kwambiri, pamene boma la malungo silikuthandizanso, koma limangovulaza thupi, tikulimbikitsidwa kumwa mapiritsi.

Aspirin amakhudza maselo am'magazi - mapulateleti, amachepetsa kuthekera kwawo kumamatirana ndikupanga ziwalo zamagazi. Kugwiritsa ntchito mankhwalawa pafupipafupi, magaziwo amakhala ndi "ziwiya" pang'ono, ndipo zotupa zimachepa pang'ono, zomwe zimapangitsa kuti magazi azithanso kukakamira komanso kupweteka kwa mutu, komanso kuthandiza popewa matenda a mtima, stroko ndi thromboembolism mwa odwala omwe ali ndi vuto la thrombosis.

Zotsatira zoyipa

Tsoka ilo, chiphunzitso cha aspirin chilinso ndi zifukwa. Chowonadi ndi chakuti kuponderezedwa kwa ntchito ya cycloo oxygenases (ma enzymes) kumakhala ndi vuto - imodzi mwa michereyi, COX-1, imayang'anira magwiridwe antchito a maselo am'mimba. Kutseka kwake kumayambitsa kuphwanya kukhazikika kwa khoma la m'mimba ndipo kumathandizira kukulitsa zilonda.

Pamene mbali iyi ya aspirin itapezeka, kuchuluka kwa momwe amagwiritsidwira ntchito kunali kocheperako: malingana ndi malamulo amakono, sinafotokozedwe kwa anthu omwe ali ndi zilonda zam'mimba. Kuphatikiza apo, mphumu ya bronchial ndiyo kuphwanya kukhazikitsidwa kwa acetylsalicylic acid. zaka zapakati pa ana osakwana zaka 12 pamaso pa matenda a tizilombo (chifukwa chokhala ndi matenda a Reye).

Opanga ndi aspirin ayesa kuchepetsa zovuta m'matumbo a m'mimba poyambira kupanga mitundu ya mapiritsi omwe amasungunuka m'madzi musanagwiritse ntchito. Komabe, zokhudza zonse zotsatira za mankhwalawo atamwa komanso kuvulaza kwake kwakukulu kwa mapiritsiwo - citric acid - pa enamel yamazino, zabwino za mawonekedwe atsopano sizinasinthidwe ndikulakwitsa kwake.

Obadwa kwa Aspirin

Koma palibe chifukwa chazovutazi - mpaka pano, akatswiri a zamankhwala aphunzira kulekanitsa zomwe zimapangitsa kupondereza ntchito ya COX yamitundu yosiyanasiyana. Mankhwala akuwoneka pamsika omwe amatha, popanda kuvulaza m'mimba, amasankha mwanzeru ma enzymes omwe amachititsa kutupa. Mankhwalawa adapanga gulu lawung'ono wosankha COX-2, ndipo tsopano akugulitsidwa kwambiri pansi pa mayina osiyanasiyana ogulitsa.

Zotsatira zina za aspirin zidatengedwanso ngati maziko a mankhwala amakono odana ndi kutupa, ma pinkiller ndi othandizira ma antiplatelet. Koma acetylsalicylic acid, ngakhale mwanjira ina yotengera "mbadwo wopita patsogolo," imakhalabe pamakanda a malo ogulitsa mankhwala ndi zida zamankhwala omwe amalembedwa m'magulu azachipatala. Ndikufuna kunena - pamsonkho, koma chifukwa chake ndi prosaic kwambiri - idakali njira yotsika mtengo kwambiri yochepetsera kutentha, kuchepetsa ululu komanso kupewa kukula kwa matenda amtima.

Mitundu, mayina ndi mitundu yotulutsira Aspirin

1. Mapale otsogola pakamwa,

2. Mapiritsi ogwiritsira ntchito mphamvu pakutha kwa madzi.

Mphamvu ya mapiritsi a Aspirin 1000 ndi Aspirin Express - 500 mg acetylsalicylic acid,
Mphamvu za mapiritsi a Asweringin C - 400 mg ya acetylsalicylic acid ndi 240 mg wa vitamini C,
Mapiritsi a mkamwa Aspirin - 500 mg,
Aspirin Cardio mapiritsi - 100 mg ndi 300 mg.

Zotsatirazi zimaphatikizidwa m'mitundu yosiyanasiyana ya Aspirin monga zinthu zothandizira:

Mphamvu za mapiritsi a Ascesin 1000, Aspirin Express ndi Aspirin C - sodium citrate, sodium carbonate, sodium bicarbonate, citric acid,
Mapiritsi amkamwa Aspirin - microcrystalline cellulose, wowuma chimanga,
Mapiritsi a Aspirin Cardio - mapadi, mapesi, chimanga, methaconic acid ndi ethyl acrylate kopolymer 1: 1, polysorbate, sodium lauryl sulfate, talc, triethyl citrate.

Kuphatikizika kwa ma synogms ena onse ndi ma generics, omwe amatanthauzanso, kutchulika dzina "Aspirin", kuli kofanana ndi omwe adapatsidwa pamwambapa. Komabe, anthu omwe akudwala chifuwa kapena kusalolerana kwa zinthu zilizonse ayenera kuwerenga mosamala kapangidwe ka Aspirin kosonyezedwa papepala lomwe lidayikidwa pa mankhwalawo.

Aspirin mapiritsi ogwira ndi pakamwa makonzedwe - zikuonetsa

1. Chizindikiro chogwiritsa ntchito popumira ululu wa kutulutsa kosiyanasiyana ndi zoyambitsa:

3. Matenda opatsirana (rheumatism, rheumatic chorea, nyamakazi yamatumbo, myocarditis, myositis).

4. Collagenoses (systemic sclerosis, scleroderma, systemic lupus erythematosus, ndi zina).

5. Pochita za allergologists ndi ma immunologists kuti achepetse chidwi cha anthu komanso mapangidwe a kulekerera kosalekeza kwa anthu omwe ali ndi "mphumu ya" aspirin "kapena" aspirin triad. "

Aspirin Cardio - zikuonetsa

Kupewa koyambirira kwa kulowerera kwa myocardial mwa anthu omwe ali pachiwopsezo cha chitukuko chake (mwachitsanzo, ndi matenda osokoneza bongo, matenda oopsa, kuthana ndi mafuta m'thupi, kunenepa kwambiri, kusuta, okalamba opitilira zaka 65),
Kupewa kwa myocardial infarction,
Kuletsa stroko,
Kupewa kwa matenda osokoneza bongo
Kupewa kwa thromboembolism pambuyo pakuchita opaleshoni yamitsempha yamagazi (mwachitsanzo.
Kupewa kwamitsempha yayikulu,
Kupewa kwa thromboembolism kwa chotupa cha m'mapapo ndi nthambi zake,
Kupewa kwa thrombosis ndi thromboembolism ndi kukhudzana kwanthawi yayitali,
Angina osakhazikika komanso odalirika
Atherosulinotic zotupa za m'matumbo a coronary (matenda a Kawasaki),
Aortoarteritis (matenda a Takayasu).

Nkhope ya nkhope ya Ziphuphu (chigoba ndi Aspirin)

Choyeretsa khungu ndikuchotsa mawanga akuda
Kuchepetsa kupanga mafuta ndi tiziwitsi tating'ono,
Makumi makumi atatu
Amachepetsa kutupa,
Imaletsa mapangidwe a ziphuphu ndi ziphuphu,
Amathetsa edema
Zimathetsa ziphuphu
Ikuchotsa maselo akufa;
Amakhala khungu.

Kunyumba, njira yosavuta kwambiri komanso yothandiza yogwiritsira ntchito Aspirin kusintha kapangidwe ka khungu ndikuchotsa ziphuphu ndi masks ndi mankhwalawa.Pokonzekera, mutha kugwiritsa ntchito mapiritsi wamba opanda chipolopolo, ogula ku pharmacy. Chophimba kumaso ndi Aspirin ndi mtundu wochepetsetsa wamankhwala omwe amapangika, motero amalimbikitsidwa kuti asachite mopitilira katatu pa sabata, ndipo masana mutagwiritsa ntchito zodzikongoletsera, musakhale pakayang'anitsitsa dzuwa.

1. Kwa khungu lamafuta ambiri ndi mafuta. Chigoba chimatsuka pores, chimachepetsa khungu ndikuchepetsa kutupa. Grind mapiritsi 4 a Aspirin kukhala ufa ndikuusakaniza ndi supuni yamadzi, onjezerani supuni ya uchi ndi mafuta a masamba (maolivi, mpendadzuwa, ndi zina). Ikani zosakaniza zakumaso ndikuzisuntha ndikusenda masekondi kwa mphindi 10, ndiye muzimutsuka ndi madzi ofunda.

2. Zachilengedwe kuti ziume khungu. Maski amachepetsa kutupa ndikufetsa khungu. Grind mapiritsi atatu a Aspirin ndikusakaniza ndi supuni ya yogati. Ikani zosakaniza zomalizidwa kumaso, chokani kwa mphindi 20 ndikutsuka ndi madzi ofunda.

3. Kwa vuto khungu ndi kutupa kwambiri. Chimakechi chimachepetsa kutukusira komanso chimalepheretsa mawonekedwe a ziphuphu zatsopano. Kuti akonze chigoba, mapiritsi angapo a Aspirin ali pansi ndikuthiridwa ndimadzi kufikira atapangidwa, omwe amamuwuza ziphuphu kapena ziphuphu ndikusiya kwa mphindi 20, ndikatsuka.

Zotsatira zoyipa

1. Matumbo:

Kupweteka kwam'mimba
Kuchepetsa mseru
Kubweza
Kutentha kwa mtima
Kutulutsa magazi m'mimba (chopondera chakuda, kusanza ndi magazi, magazi amatsenga mu ndowe),
Kuchepetsa magazi
Zilonda zam'mimba komanso zam'mimba.
Kuchulukitsa kwa ma enzymes a chiwindi (AsAT, AlAT, etc.).

2. Pakati mantha dongosolo:

Kutaya magazi ambiri
Kutulutsa kwa kutulutsa kuthekera kosiyanasiyana (nose, gingival, uterine, etc.),
Hemorrhagic purpura,
Mapangidwe a hematomas.

4. Zotsatira zoyipa:

Ma Analogs a Aspirin

Aspivatrin mapiritsi ogwira,
Mapiritsi a Aspen ndi mapiritsi ogwira ntchito,
Mapiritsi a Aspitrin,
Asprovit effervescent mapiritsi,
Acetylsalicylic acid mapiritsi,
Mapiritsi a Atsbirin ogwira ntchito,
Mapiritsi a Nekstrim Fast,
Mapiritsi olimbitsa thupi a Taspir,
Mapiritsi a Upsarin Upsa
Fluspirin mapiritsi ogwira ntchito.

Mgwirizano wa Aspirin C ndi awa:

Aspivit effeedcent mapiritsi,
Aspirate C ogwiritsa mapiritsi,
Asprovit C ogwira ntchito mapiritsi
Upsarin Upsa wokhala ndi mapiritsi a Vitamin C a mphamvu.

Kuyanjana kwa Aspirin Cardio ndi awa:

Aspirin ndi Aspirin Cardio - mtengo

Aspirin C ogwiritsa mapiritsi 10 - 165 - 241 ma ruble,
Aspirin Express 500 mg 12 zidutswa - 178 - 221 rubles,
Mapiritsi a Aspirin amkamwa makonzedwe, 500 mg 20 zidutswa - 174 - 229 rubles,
Aspirin Cardio 100 mg 28 mapiritsi - 127 - 147 ma ruble,
Aspirin Cardio 100 mg 56 mapiritsi - 225 - 242 ma ruble,
Aspirin Cardio 300 mg 20 mapiritsi - 82 - 90 ma ruble.

Kodi pali kusiyana kotani pakati pa ASPIRIN ndi Acetylsallicylic Acid Mapiritsi.

koma analgin (metamizole sodium kapena sodium mchere (2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl) methylamino methanesulfonic acid, mankhwala ochokera ku gulu la antipyrine) pazonsezi alibe chilichonse chochita! awa ndi mankhwala osiyana ndi ena onse, komanso analgesic ndi antipyretic, koma kapangidwe kake kake ndizosiyana kotheratu! mwa njira, inali yoletsedwa kale pafupifupi m'maiko onse kuti apange ndi kugulitsa chifukwa cha zotsatira zoyipa

Aspirin ndi mankhwala osokoneza bongo a anti-yotupa-NSAID. Amakhulupirira kuti dzina loti "Aspirin" limapangidwa ndi magawo awiri: "a" - kuchokera ku acetyl ndi "spir" - kuchokera ku Spiraea (monga chomera cha meadowsweet chimatchedwa Latin, kuchokera pomwe salicylic acid adadzipatula kumene).

Kwa zaka zopitilira 100, Aspirin wakhala akugwiritsidwa ntchito ngati mankhwala ngati antipyretic ndi analgesic. Ndi kangati kamene timamwa piritsi la Aspirin pa kutentha ndi kuwawa. Mankhwalawa okwera mtengo komanso othandiza kwambiri ayenera kupezeka m'banja la aliyense m'nyumba yanyumba yamankhwala.

Machitidwe.Anti-yotupa, antipyretic ndi analgesic. Zizindikiro. Rheumatism, kupweteka mutu, mano, myalgia, neuralgia, malungo, thrombophlebitis, kupewa myocardial infarction. Njira yoyendetsera ndi kumwa. Mankhwala amatengedwa pakamwa pambuyo chakudya. Piritsi imaphwanyidwa ndikutsukidwa ndi madzi ambiri, makamaka mkaka. Akuluakulu amalamula 0,3-1 g pa mlingo mpaka pazokwanira tsiku lililonse la 4 g ana kwa tsiku lililonse malinga ndi zaka: mpaka miyezi 30 - 0.025-0.05 g kuyambira zaka ziwiri mpaka zaka 4 - 0,2-0, 8 g kuchokera zaka 4 mpaka zaka 10 mpaka 1 g kuchokera zaka 10 mpaka 15pet-0.5-1,5 g. Mlingo wa tsiku ndi tsiku umagawidwa muyezo waukulu. Zotsatira zoyipa. Dyspepsia, kutulutsa magazi m'mimba, tinnitus, kumva kusamva, thupi lawo siligwirizana, zotsutsana ndi ACETYL SALICYLIC ACID (ASPIRINE). . Zilonda zam'mimba ndi duodenal, chizolowezi chowukha magazi, gout, matenda a impso, pakati. ACETYL SALICYLIC ACID (ASPIRINE

Acetylsalicylic acid amadziwika kwambiri pansi pa dzina la mtundu wa Bayer "Aspirin".

Njira yamachitidwe

Acetylsalicylic acid imalepheretsa kupangika kwa ma prostaglandins ndi ma thromboxanes, chifukwa ndi cholepheretsa kusintha kwa cycloo oxygenase (PTGS), puloteni yotengera zochita zawo. Acetylsalicylic acid imagwira ntchito ngati acetylating ndipo imalumikiza gulu la acetyl kumalo otsalira a serine omwe ali pakati pa cycloo oxygenase.

Machitidwe a antiaggregant

Mbali yofunika kwambiri ya acetylsalicylic acid ndi kuthekera kwake ndi mphamvu ya antiplatelet, i.e. ziletsa zokha komanso kuti mukulumize kuphatikizira kwa maplateni.

Zinthu zomwe zimakhala ndi antiplatelet zotsatira zake zimagwiritsidwa ntchito ngati mankhwala popewa kuwonongeka kwa magazi mwa anthu omwe ali ndi vuto losakanizira lamatumbo, ngozi yamitsempha, ndi mawonetseredwe ena a atherosulinosis (mwachitsanzo, angina pectoris, claudication yapakati pake, komanso oopsa pamtima. Chiwopsezochi chimawerengedwa kuti ndi "chokwera kwambiri" pamene chiwopsezo chokhala ndi infrction yam'mimba yopanda magazi kapena kufa chifukwa cha matenda amtima pazaka 10 zikubwera kuposa 20%, kapena chiopsezo cha kufa chifukwa cha matenda amtima aliyense (kuphatikiza stroko) m'zaka 10 zikubwerazi.

Ndi vuto la magazi, mwachitsanzo, ndi hemophilia, kuthekera kwa kutulutsa magazi kumakulanso.

Aspirin, ngati njira yoyambira ndi yachiwiri ya prophylaxis ya atherosulinosis, ingagwiritsidwe ntchito bwino muyezo / tsiku, mlingo wake umagwiritsidwa ntchito moyenera pakukula kwake / chitetezo.

Zotsatira zoyipa

Mankhwala osokoneza bongo tsiku lililonse otseguka: 4 ga. Olemba mbiri ya zamankhwala amakhulupirira kuti kugwiritsidwa ntchito kwakukulu kwa aspirin (mzere) kunachulukitsa kufa kwa mliri wa chimfine cha 1918. Mukamagwiritsa ntchito mankhwalawa, thukuta labodza limatha kuyambanso, tinnitus ndi kusamva kwamakutu, angioedema, khungu ndi zina zomwe zimayambitsa thupi.

Otchedwa ulcerogenic (kuchititsa kuwoneka kapena kukulitsa zilonda zam'mimba ndi / kapena zilonda zam'mimba) mchitidwewo umakhala wofanana mpaka wina kapena magulu amitundu yonse ya mankhwala othandizira kutupa: onse corticosteroid komanso osakhala a steroidal (mwachitsanzo, butadione, indomethacin, etc. Imafotokozedwa osati kokha ndi kuphatikizika kwa mphamvu (kuletsa kwa kusintha kwa magazi, zina), komanso ndi kukwiya kwake kwachindunji pamatumbo a m'mimba, makamaka ngati mankhwalawa imwani ngati mapiritsi osagwedezeka. Izi zimagwiranso ntchito kwa sodium salicylate .Kutalika, popanda kuyang'aniridwa ndi achipatala, kugwiritsa ntchito acetylsalicylic acid, zotsatira zoyipa monga kusokonezeka kwa magazi ndi kuwonongeka kwa m'mimba zimatha kuwonedwa.

Kuti muchepetse ulcerogenic zotsatira ndi kutuluka kwa m'mimba, muyenera kumwa acetylsalicylic acid (ndi sodium salicylate) mutatha kudya, tikulimbikitsidwa kupera miyala komanso kumwa madzi ambiri (makamaka mkaka). Komabe, pali umboni kuti magazi am'mimba amatha kupezekanso ndi acetylsalicylic acid mukatha kudya. Sodium bicarbonate imathandizira kutulutsa masalicylates ambiri mthupi, komabe, kuti achepetse mkwiyo pamimba, amayamba kumwa madzi amchere a mchere kapena njira ya sodium bicarbonate pambuyo pa acetylsalicylic acid.

Kunja, mapiritsi acetylsalicylic acid amapangidwa kuchokera ku chipolopolo (chosagwira asidi) kuti apewe kulumikizana mwachindunji ndi ASA ndi khoma la m'mimba.

Pogwiritsa ntchito salicylates kwanthawi yayitali, mwayi wokhala ndi vuto la kuchepa magazi uyenera kukumbukiridwa ndipo kuyezetsa magazi mwadongosolo kuyenera kuchitidwa ndipo magazi ayenera kuyang'aniridwa ndowe.

Chifukwa cha zovuta zomwe zimayambitsa thupi, kusamala kuyenera kugwiritsidwa ntchito popereka acetylsalicylic acid (ndi salicylates) kwa anthu omwe ali ndi chidwi chambiri ndi penicillin ndi mankhwala ena "allergenic".

Ndi chiwopsezo chowonjezereka cha acetylsalicylic acid, mphumu ya aspirin imatha kupezeka, popewa ndi kuchiza komwe njira zochotsera zakumwa zimapangidwira pogwiritsa ntchito kuchuluka kwa aspirin.

Tiyenera kudziwa kuti mothandizidwa ndi acetylsalicylic acid, mphamvu ya anticoagulants (zotumphukira za coumarin, heparin, etc.), mankhwala ochepetsa shuga (omwe amachokera ku sulfonylureas) amawonjezeka, chiwopsezo cha kutaya magazi m'mimba chikuwonjezereka pamene kugwiritsidwa ntchito kwa corticosteroids ndi mankhwala osapatsirana a anti-yotupa (NSAIDs). Mphamvu ya furosemide, uricosuric agents, spironolactone imakhala yofooka.

Mu ana ndi amayi apakati

Pokhudzana ndi deta yoyeserera ya teratogenic mphamvu ya acetylsalicylic acid, tikulimbikitsidwa kuti tisapereke mankhwala ndi kukonzekera komwe muli nako kwa akazi mu miyezi itatu yoyambirira ya pakati.

Kumwa mankhwala osapweteka a narcotic (aspirin, ibuprofen ndi paracetamol) panthawi yapakati kumawonjezera chiopsezo cha kusabereka kwamtundu wamwamuna mwa anyamata obadwa mwanjira ya cryptorchidism. Zotsatira za kafukufukuyu zikuwonetsa kuti kugwiritsa ntchito nthawi imodzi kwamankhwala awiri mwa atatu omwe atchulidwa pa nthawi ya pakati kumawonjezera mwayi wokhala ndi mwana ndi cryptorchidism mpaka nthawi 16 poyerekeza ndi azimayi omwe sanamwe mankhwalawa.

Pakadali pano, pali umboni wa chiopsezo cha kugwiritsidwa ntchito kwa acetylsalicylic acid mu ana ndi cholinga chochepetsa kutentha panthawi ya fuluwenza, kupuma kwamphamvu ndi matenda ena achisoni pokhudzana ndi milandu ya chitukuko cha Reye's syndrome (Reye) (hepatogenic encephalopathy). Ma pathogenesis omwe amapanga chitukuko cha Reye's syndrome sakudziwika. Matendawa amapitilira ndi kukula kwa pachimake chiwindi cholephera. Ziwopsezo za matenda a Reye pakati pa ana ochepera zaka 18 ku United States ndi pafupifupi 1: pomwe chiwopsezo cha imfa chimaposa 36%.

Katundu wa zinthu

Acetylsalicylic acid ndi oyera ang'ono ngati makhitala ofiira kapena ufa wowoneka ngati galasi, wosungunuka pang'ono m'madzi kutentha kwa chipinda, sungunuka m'madzi otentha, sungunuka mosavuta mu mowa, mayankho a caustic ndi carbonic alkalis.

Acetylsalicylic acid amawola nthawi ya hydrolysis kukhala salicylic ndi acetic acids. Hydrolysis imachitika ndi kuwiritsa yankho la acetylsalicylic acid m'madzi a 30 s. Pambuyo pozizira, salicylic acid, osasungunuka bwino m'madzi, imatulutsa mawonekedwe a makhwala a fluffy singano.

Kuchuluka kwa acetylsalicylic acid kumachitika chifukwa cha kukokomeza kwa Cobert pamaso pa sulfuric acid (magawo awiri a sulfuric acid, gawo limodzi la reagent la Cobert): yankho limatembenuka pinki (nthawi zina amafunikira). Acetylsalicylic acid amachita pamenepa amakhala wofanana ndi salicylic acid.

Aspirin ndi mankhwala osagwiritsa ntchito mankhwala osokoneza bongo omwe amathandizira kuchepetsa ululu, kuchepetsa kutentha thupi, komanso ngati prophylaxis ya thrombosis.

The yogwira mankhwala - acetylsalicylic acid - ali ndi analgesic (analgesic), antipyretic, waukulu Mlingo - odana ndi kutupa kwenikweni. Imakhala ndi antiaggregant (kuletsa mapangidwe a magazi a magazi).

Njira yayikulu yogwiritsira ntchito acetylsalicylic acid ndi inactivation yosasinthika (kuponderezana kwa zochitika) ya cycloo oxygenase enzyme (puloteni yomwe imakhudzana ndi kapangidwe ka prostaglandins m'thupi), chifukwa chomwe kuphatikiza kwa ma prostaglandins kusokonezeka. (Prostaglandins ndi zinthu zamoyo zomwe zimapangidwa m'thupi. Udindo wawo m'thupi umasinthasintha, makamaka, amachititsa kuti mawonekedwe a ululu azitupa komanso azitupa.

Nthawi zambiri, aspirin wokwanira Mlingo waukulu (300 mg - 1 g) amagwiritsidwa ntchito kuchepetsa kutentha kwa odwala omwe ali ndi vuto la kupuma kwamatendawa komanso chimfine, kuchepetsa minofu, molumikizana komanso kumutu.

Kodi Aspirin amathandizira ndi otsogola?

Nthawi zambiri, mankhwalawa amathandiza kulimbana ndi hangover syndrome. Mapiritsi okhala ndi mphamvu ndi oyenera kusungunuka m'madzi ndikumwa. Amapangidwa mwapadera kuti athane ndi zisonyezo za hangover ndipo ali ndizowonjezera zapadera (zowonjezera ndi vitamini C) zomwe zimakhala ndi zovuta pakhungu.

Choyamba, Aspirin "amawunikira magazi" ndikuchepetsa kuthamanga kwa mkati, chifukwa pomwe wodwalayo amasangalala pambuyo poti wayamba.

Amadwala mutu ndipo kuzindikira kwake kumamveka bwino. Kuphatikiza apo, mowa umayambitsa makulidwe amwazi, omwe amatha kuyambitsa magazi m'mitsempha, ndi acetylsalicylic acid, m'malo mwake, amawumitsa.

Malangizo ogwiritsira ntchito mlingo wa Aspirin

Mapiritsi okhala ndi mapiritsi pamtunda wa 325 mg (400-500 mg ndi pamwambapa) adapangidwa kuti azigwiritsidwa ntchito ngati analgesic komanso anti-yotupa - mu Mlingo kuchokera 50 mpaka 325 mg - makamaka ngati mankhwala a antiplatelet.

Mapiritsi ochiritsira amatengedwa pakamwa ndi madzi ambiri (galasi), mapiritsi am'madzi oyendetsedwa kale amasungunuka mu kapu yamadzi (mpaka kuthetseratu ndi kuyeretsa kwake).

Akuluakulu ndi ana opitilira zaka 15 zokhala ndi ululu wamatenda ofatsa pang'ono komanso athanzi, malangizo ogwiritsira ntchito amalimbikitsa mlingo wa Aspirin:

Mlingo umodzi kuchokera 500 mg mpaka 1 g,
muyeso umodzi umodzi ndi 1 g,
pazipita tsiku lililonse 3 mg.

Pazotheka pakati Mlingo wa mankhwala ayenera kukhala osachepera maola 4.

Nditha kumwa aspirin mpaka liti? Kumwa mankhwalawa (popanda kufunsa dokotala) sikuyenera kupitirira masiku 7 mutapatsidwa mankhwala osokoneza bongo komanso masiku opitilira 3 ngati antipyretic.

Kupititsa patsogolo magazi m'thupi - kuyambira 150 mpaka 250 mg patsiku kwa miyezi ingapo.

Ndi kulowetsedwa kwa myocardial, komanso kupewa kwachiwiri kwa odwala pambuyo panjira ya infarction, Aspirin amatengedwa pa mlingo wa 40 mpaka 325 mg 1 nthawi patsiku (nthawi zambiri 160 mg).

Monga zoletsa za kuphatikiza kwa maselo ambiri - 300-325 mg tsiku lililonse kwa nthawi yayitali.

Ndi kusokonezeka kwamphamvu kwa cerebrovascular in men, ubongo wa thromboembolism - 325 mg patsiku ndi kuwonjezeka pang'onopang'ono mpaka 1 1 patsiku. Popewa kubwereranso - 125-300 mg patsiku.

Pofuna kupewa thrombosis kapena kung'ambika kwa aortic shunt, 325 mg maola 7 aliwonse kudzera mu chubu cham'mimba, ndiye kuti 325 mg pamlomo katatu katatu patsiku (nthawi zambiri amaphatikizidwa ndi dipyridamole, yemwe umathetsedwa pakatha sabata, akupitilira chithandizo chanthawi yayitali ndi ASA.

Pakadali pano, kugwiritsa ntchito Aspirin ngati mankhwala osokoneza bongo tsiku lililonse la 5-8 g ndi ochepa, chifukwa chakuwoneka bwino kwa zotsatira zoyipa m'matumbo (NSAIDs gastropathy).

Pamaso pa opaleshoni, kuti muchepetse magazi munthawi ya opaleshoni komanso munthawi ya opaleshoni, muyenera kuletsa kudikirira masiku 5-7 ndikuuza dokotala.

Pogwiritsa ntchito mankhwala a Aspirin kwa nthawi yayitali, kuyezetsa magazi komanso kuyeserera kochita zamatsenga kumayenera kuchitika.

Ngakhale Mlingo wocheperako, amachepetsa kuyamwa kwa uric acid m'thupi, komwe kungapangitse kuti chiwopsezo cha matenda otupa atuluke mosavuta.

Analogs Aspirin, mtengo pama pharmacies

Ngati ndi kotheka, mutha kusintha Aspirin ndi analogue yogwira mankhwala - awa ndi mankhwala:

Mukamasankha analogi, ndikofunikira kumvetsetsa kuti malangizo ogwiritsira ntchito Aspirin, mtengo ndi kuwunika kwa mankhwala omwe ali ndi zotsatira zofananira sizikugwira ntchito. Ndikofunikira kupeza upangiri wa dokotala komanso kuti usasinthe popanda mankhwala.

Mtengo m'mafakitale aku Russia: mapiritsi am'madzi a Aspirin amafotokozera 500mg 12pcs. - kuchokera ku ruble 230 mpaka 305, mapiritsi 300 mg 20 ma PC. - kuchokera ku ruble 75 mpaka 132, malinga ndi mafakitale a 932.

Sungani pamalo owuma pa kutentha osaposa 30 ° C. Moyo wa alumali ndi zaka 5. Migwirizano yachokere ku malo ogulitsa mankhwala - popanda kulandira mankhwala.

Kuyanjana kwa mankhwala osokoneza bongo

Acetylsalicylic acid timapitiriza poizoni zimatha methotrexate, komanso osafunika zotsatira za triiodothyronine, narcotic analgesics, sulfanilamides (kuphatikiza co-trimoxazole), NSAIDs ena, thrombolytics - kupatsidwa zinthu za m'magazi inhibitors, hypoglycemic ya pakamwa makonzedwe, anticoagulant. Nthawi yomweyo, imafooketsa mphamvu ya okodzetsa (furosemide, spironolactone), mankhwala a antihypertensive, komanso uricosuric mankhwala (probenecid, benzbromarone).

Mukaphatikizidwa ndi mankhwala okhala ndi ethanol, mowa ndi glucocorticosteroids, zotsatira zowonongeka za ASA pamatumbo am'mimba zimawonjezeka, zomwe zimapangitsa kuti magazi azituluka m'matumbo.

Acetylsalicylic acid imachulukitsa ndende ya lithiamu, barbiturates ndi digoxin m'thupi pogwiritsa ntchito munthawi yomweyo. Maantacid, omwe amaphatikizapo aluminium ndi / kapena magnesium hydroxide, amachepetsa ndikuchepetsa kuyamwa kwa ASA.

Kodi aspirin ndi yabwino kapena yoipa kwa thupi?

Ubwino wa Aspirin ndikuti umathandizira bwino ngati analgesic, antipyretic komanso anti-kutupa othandizira. Mlingo wocheperako, umagwiritsidwa ntchito poletsa kukula kwa mtima.

Masiku ano ndiokhawo komwe kumagwirizana, kugwiritsa ntchito bwino komwe kumagwiritsidwa ntchito panthawi yovuta kwambiri ya ischemic stroke (matenda obanika) kumathandizidwa ndi mankhwala ofotokoza umboni.

Ndi kugwiritsa ntchito pafupipafupi, chiopsezo cha khansa ya colorectal, komanso khansa ya prostate, mapapu, esophagus ndi mmero, chimachepetsedwa kwambiri.

Mbali yofunikira pakupindulitsa kwa Aspirin ndikuti imalepheretsa COX, enzyme yomwe imakhudzidwa ndi kapangidwe ka thromboxanes ndi Pg. Kugwira ntchito ngati acetylating, ASA imalumikizidwa ndi zotsalira za serine pakatikati kogwira gulu la COX acetyl. Izi zimasiyanitsa mankhwalawo ndi ena a NSAIDs (makamaka, kuchokera ku ibuprofen ndi diclofenac), omwe ali m'gulu la COX inhibitors.

Omanga a thupi amagwiritsa ntchito kuphatikiza kwa Aspirin-Caffeine-Broncholitin ngati chowotchera mafuta (osakaniza awa amawonedwa kuti ndiye amayambitsa onse owotcha mafuta). Amayi apanyumba adapeza kugwiritsidwa ntchito kwa ASA m'moyo watsiku ndi tsiku: zomwe zimagwiritsidwa ntchito nthawi zambiri zimagwiritsa ntchito kuchotsa zothimbirira thukuta zovala zoyera komanso kuthirira dothi lomwe lakhudzidwa ndi bowa.

Aspirin adapezanso mapindu a maluwa - piritsi lophwanyika limawonjezeredwa ndi madzi akamafuna kuti azidula mbewu yayitali.

Amayi ambiri amagwiritsa ntchito piritsi ngati njira yolerera: piritsi imaperekedwa kwa mphindi 10 mpaka 15 musanayambe PA kapena kuisungunula m'madzi kenako ndikutsegula ndi yankho lake. Kuchita bwino kwa njira yodzitetezera ku pakati sikunafufuzidwe, komabe, akatswiri azamankhwala satsutsa ufulu wokhala nawo.Nthawi yomweyo, madotolo amazindikira kuti mphamvu zakulera zotere zimangokhala 10%.

Phindu ndi zovuta za Aspirin zimadalira kugwiritsa ntchito moyenera ndikutsatira malangizowo, ndipo ngakhale kuli kwazambiri zofunikira, mankhwalawo amatha kukhala ovulaza. Chifukwa chake, kuponderezana ndi ntchito ya COX kumayambitsa kuphwanya umphumphu wa makhoma am'mimba chimbudzi ndipo ndikuthandizira kukulitsa zilonda zam'mimba.

Komanso, ASA yoopsa imatha kukhala ya ana osakwana zaka 12. Ngati agwiritsidwa ntchito ngati mwana ali ndi kachilomboka, mankhwalawa amatha kuyambitsa matenda a Reye, matenda omwe amawopseza moyo wa odwala.