Lipoic acid wamtundu wa shuga
Tikukupemphani kuti muwerenge nkhaniyi pamutuwu: "lipoic acid mu shuga" ndi ndemanga kuchokera kwa akatswiri. Ngati mukufuna kufunsa funso kapena kulemba ndemanga, mutha kuchita izi pansipa, nkhaniyo itatha. Katswiri wathu wamtundu wa endoprinologist adzakuyankhirani.
Lipoic (thioctic) acid umaphatikizidwa ndi kagayidwe kazachilengedwe ndipo umalimbikitsa kusintha kwa glucose kukhala mphamvu. Ndi antioxidant ndipo imathandizira kuti mitundu yosiyanasiyana yaulere ipite. Izi zimapezeka muzakudya zambiri, koma ambiri amalangizidwa kuti azimwa mosiyana, monga gawo limodzi la chithandizo chovuta kwambiri cha matenda ashuga. Momwe mungatenge mankhwala a lepic acid ngati mtundu wa 2 wodwala matenda ashuga adzauzidwa ndi endocrinologist.
Kanema (dinani kusewera). |
Ndi matenda a shuga omwe akupita patsogolo komanso pang'onopang'ono akamakula m'magazi a shuga, mphamvu yamanjenje imawonongeka. Mavuto amayamba chifukwa cha kupangika kwa zinthu za glycolised zomwe zimakhudza misempha. Chifukwa cha kuchuluka kwa shuga m'magazi, kufalikira kwa magazi kumawonjezereka, chifukwa, kukonza minyewa kumachepa.
Kanema (dinani kusewera). |
Kuzindikiritsidwa kwa matenda a diabetesic neuropathy kungachitike ngati pali zizindikiro zoyenera:
- kudumphira m'magazi,
- dzanzi la miyendo
- kumva m'miyendo, mikono,
- kupweteka
- chizungulire
- mavuto ndi erection mwa amuna
- mawonekedwe a kutentha kwadzuwa, kudzimbidwa, kukhumudwa kwambiri, ngakhale ndi chakudya chochepa chomwe chidadyedwa.
Kuti mupeze matenda olondola, ma reflexes amayendera, kuthamanga kwa mitsempha kumayesedwa, electromyograph imapangidwa. Mukatsimikizira neuropathy, mutha kuyesa kusintha matenda pogwiritsa ntchito α-lipoic acid.
Lipoic acid ndi mafuta acid. Ili ndi sulufule yambiri. Ndi madzi ndi madzi sungunuka, amatenga nawo mbali pakapangidwe ka cell membrane ndipo amateteza maselo a cell ku pathological zotsatira.
Lipic acid amatanthauza ma antioxidants omwe amatha kuletsa zotsatira za kusintha kwaulere. Amagwiritsidwa ntchito pochiza matenda ashuga a polyneuropathy. Katunduyo ndi wofunikira chifukwa:
- amatenga nawo mbali pakuchepa kwa shuga ndikuchotsa mphamvu,
- imateteza maselo a cell ku zotsatira zoyipa zama radicals aulere,
- ili ndi mphamvu ya insulin: imawonjezera zochitika zaonyamula shuga mu cytoplasm of cell, ikuthandizira njira yamatenda a glucose omwe amapangidwa ndi minofu,
- ndi antioxidant wamphamvu, wofanana ndi mavitamini E ndi C.
Ichi ndi chimodzi mwazinthu zabwino kwambiri zothandizira odwala matenda ashuga. Nthawi zambiri amalimbikitsa poika mankhwala okwanira. Amawerengedwa kuti ndi antioxidant wabwino, chifukwa asidi awa:
- odzipereka ku chakudya
- Amasinthidwa maselo kuti akhale omasuka,
- kawopsedwe kochepa
- ili ndi ntchito zosiyanasiyana zoteteza.
Mukamamwa, mutha kuthana ndi mavuto angapo omwe amadza chifukwa cha kuwonongeka kwa makulidwe amtundu wa oxidative.
Mthupi, thioctic acid imagwira ntchito zotsatirazi:
- imalepheretsa zowopsa zaulere zamagetsi ndikuisokoneza njira ya makutidwe ndi okosijeni,
- imabwezeretsa ndikupangitsa kuti igwiritsenso ntchito antioxidants amkati: mavitamini C, E, coenzyme Q10, glutathione,
- chimamangirira zitsulo zakumwa zoziziritsa kukhosi ndikuchepetsa kupanga ma free radicals.
Asidi omwe atchulidwa ndi gawo limodzi lachitetezo cha thupi. Chifukwa cha ntchito yake, ma antioxidants ena amabwezeretsedwa, atha kutenga nawo gawo mu kagayidwe ka nthawi yayitali.
Malinga ndi dongosolo la biochemical, chinthu ichi ndi chofanana ndi mavitamini a B. Mu 80-90s ya zaka zapitazi, asidi awa amatchedwa mavitamini a B, koma njira zamakono zapangitsa kuti amvetsetse kuti ili ndi mitundu yosiyanasiyana ya biochemical.
Acid imapezeka mu ma enzymes omwe amathandizira kukonza zakudya. Ikapangidwa ndi thupi, kuchuluka kwa shuga kumachepa, ndipo ndizofunikira kwambiri kwa odwala matenda ashuga.
Chifukwa cha antioxidant zotsatira ndi kumangika kwa ma radicals aulere, zovuta zawo pazovuta zimalepheretsedwa. Thupi limachepetsa kukalamba ndipo limachepetsa kupsinjika kwa oxidative.
Acid iyi imapangidwa ndi minofu ya chiwindi. Amapangidwa kuchokera ku chakudya chomwe chikubwera. Kuti muwonjezere kuchuluka kwake, tikulimbikitsidwa kugwiritsa ntchito:
- nyama yoyera
- broccoli
- sipinachi
- nandolo zobiriwira
- Tomato
- Brussels imamera
- mpunga.
Koma pazinthu, izi zimagwirizanitsidwa ndi amino acid a mapuloteni (ndiwo, lysine). Ili ndi mtundu wa R-lipoic acid. Kuchulukitsa kwakukulu, antioxidant iyi imapezeka mu ziwalo za nyama zomwe zimagwira ntchito kwambiri. Kuzungulira kwakukulu, kumatha kupezeka impso, chiwindi ndi mtima.
Pokonzekera thioctic acid, imaphatikizidwa mwaulere mawonekedwe. Izi zikutanthauza kuti sizimagwirizana ndi mapuloteni. Mukamagwiritsa ntchito mankhwala apadera, kuchuluka kwa asidi m'thupi kumawonjezera nthawi 1000. Ndikosatheka kupeza 600 mg pazinthu izi kuchokera ku chakudya.
Akonzekereratu kukonzekera kwa lipoic acid a shuga:
Musanagule chinthu, funsani ndi dokotala.
Popeza mwasankha kusintha magwiritsidwe a shuga ndi ziwalo ndi machitidwe mothandizidwa ndi lipoic acid, muyenera kumvetsetsa dongosolo la kudya. Zinthu zina zimapezeka mwanjira ya mapiritsi kapena makapisozi, zina mwa njira yothetsera kulowetsedwa.
Pazifukwa zodzitetezera, mankhwalawa amatchulidwa ngati mapiritsi kapena mapiritsi. Iwo aledzera katatu patsiku kwa 100-200 mg. Ngati mumagula mankhwalawa muyezo wa 600 mg, ndiye kuti mlingo umodzi patsiku uzikhala wokwanira. Mukamamwa zowonjezera ndi R-lipoic acid, ndikokwanira kumwa 100 mg kawiri patsiku.
Kugwiritsa ntchito mankhwala molingana ndi chiwembuchi kungalepheretse zovuta za matenda ashuga. Koma muyenera kumwa mankhwalawa kokha pamimba yopanda kanthu - ola limodzi musanadye.
Mothandizidwa ndi asidi, mutha kuyesa kuchepetsa kuwonetsa kwa zovuta monga matenda a shuga. Koma chifukwa cha izi, kayendetsedwe ka intravenous mu mawonekedwe a njira zapadera m'malo ambiri kwanthawi yayitali.
Izi zimaphatikizidwa pakuphatikizidwa kwa ma multivitamini ena mpaka 50 mg. Koma kukwaniritsa zabwino pa thupi la munthu wodwala matenda ashuga komanso kudya acid mu Mlingo woterewu ndizosatheka.
Limagwirira zake mankhwala a matenda ashuga neuropathy
Zotsatira za antioxidant za lipoic acid zatsimikiziridwa ndi maphunziro ambiri. Amachepetsa kupsinjika kwa oxidative ndipo amathandizira thupi.
Ndi neuropathy, iyenera kuperekedwa kudzera m'mitsempha. Chithandizo cha nthawi yayitali chimapereka zotsatira. Mitsempha yomwe yakhudzidwa ndi kupitirira kwa shuga kuchokera pamaukidwe amkokedwe wa glucose pang'onopang'ono imachira. Njira yakukonzanso kwawo kwathandizira.
Anthu odwala matenda ashuga ayenera kudziwa kuti matenda ashuga a polyneuropathy amawoneka ngati matenda osinthika. Chachikulu ndikusankha njira yoyenera yothandizira ndikutsatira malangizo onse a madokotala. Koma popanda zakudya zapadera za carb, kuchotsa shuga ndi zovuta zake sizingathandize.
Mothandizidwa ndi pakamwa pa cy-lipoic acid, kuphatikiza kwakukulu kumawonedwa pambuyo pa mphindi 30-60. Amatengeka mwachangu m'magazi, koma amathandizidwanso mwachangu. Chifukwa chake, mukamamwa mapiritsi, kuchuluka kwa shuga kumakhala kosasinthika. Kuzindikira kwa minofu kupita ku insulin kumawonjezeka pang'ono.
Ndi mlingo umodzi wa 200 mg, bioavailability wake ali pamlingo wa 30%. Ngakhale ndi chithandizo chopitilira masiku ambiri, chinthu ichi sichimadziunjikira m'magazi. Chifukwa chake, kuudya pofuna kuthana ndi kuchuluka kwa glucose ndikosatheka.
Ndi kukhuthala kwa mankhwalawa, mlingo wofunikira umalowa m'thupi mkati mwa mphindi 40. Chifukwa chake, ntchito yake imachulukitsidwa. Koma ngati chiphuphu cha matenda a shuga sichingatheke, ndiye kuti zilembo za matenda ashuga zidzabweza pakapita nthawi.
Anthu ena amalimbikitsa kumwa mapiritsi a zakudya a lipoic acid. Kupatula apo, amatenga nawo gawo pama metabolism a mafuta ndi mafuta. Koma ngati simutsatira mfundo zachakudya zoyenera, kukana masewera olimbitsa thupi, kusiya kulemera mopitirira muyeso ndimamwa mapiritsi sikugwira ntchito.
Kukonzekera mankhwala a thioctic acid nthawi zina kumachitika limodzi ndi kukonzekera zotsatira zoyipa:
- mavuto a dyspeptic
- mutu
- kufooka.
Koma amawoneka, monga lamulo, ndi mankhwala osokoneza bongo.
Odwala ambiri amayembekeza kuti athetse matenda a shuga pomwa mankhwalawa. Koma kukwaniritsa izi ndizosatheka. Kupatula apo, siziunjikira, koma imakhala ndi nthawi yochepa yochizira.
Monga gawo la zovuta mankhwala, endocrinologist angalimbikitse kugwiritsa ntchito lipoic acid kwa odwala matenda ashuga. Chida ichi ndi antioxidant, chimachepetsa zovuta zoyipa zama radicals omasuka m'thupi.
Udindo wa lipoic acid mthupi
Lipoic kapena thioctic acid amagwiritsidwa ntchito kwambiri pamankhwala. Mankhwala ozikidwa pa mankhwalawa amagwiritsidwa ntchito kwambiri pochiza matenda amtundu wa 2 komanso matenda a shuga. Komanso, mankhwalawa amagwiritsidwa ntchito popanga zovuta za matenda a chitetezo cha m'thupi komanso matenda am'mimba.
Lipoic acid adasiyanitsidwa koyamba ndi chiwindi cha ng'ombe mu 1950. Madotolo awona kuti phula ili limathandizira pakuchitika kwa mapuloteni m'thupi.
Chifukwa chiyani a lepic acid amagwiritsidwa ntchito ngati matenda a shuga a 2? Izi ndichifukwa choti thunthu limakhala ndi zinthu zingapo zothandiza:
- Lipoic acid amathandizira pakuphulika kwa mamolekyulu a shuga. Zakudyazi zimakhudzidwanso pantchito ya ATP mphamvu synthesis.
- Mankhwala ndi antioxidant wamphamvu. Pogwira ntchito yake, siyotsika ndi vitamini C, tocopherol acetate ndi mafuta a nsomba.
- Thioctic acid amathandizira kulimbikitsa chitetezo chokwanira.
- Nutrient ali ndi katundu wotchedwa insulin. Zinapezeka kuti chinthucho chimathandizira kuwonjezeka kwa zochitika zamkati zamatumbo a glucose mu cytoplasm. Izi zimakhudza njira yogwiritsira ntchito shuga mu minofu. Ichi ndichifukwa chake lipoic acid imaphatikizidwa ndi mankhwala ambiri amtundu wa 1 komanso matenda a shuga a 2.
- Thioctic acid imawonjezera kukana kwa thupi chifukwa cha ma virus ambiri.
- Nutrient imabwezeretsa antioxidants amkati, kuphatikizapo glutatitone, tocopherol acetate ndi ascorbic acid.
- Lipoic acid amachepetsa mavuto omwe amayambitsidwa ndi poizoni pama cell cell.
- Nutrient ndi sorbent yamphamvu. Zatsimikiziridwa mwasayansi kuti chinthucho chimamangiriza poizoni ndi magulu awiri azitsulo zolemera muzitsulo za chelate.
Mkuyesa kambiri, zidapezeka kuti alpha lipoic acid imakulitsa chidwi cha maselo kuti apange insulin. Izi ndizofunikira makamaka kwa matenda ashuga amtundu 1. Thupi limathandizanso kuchepetsa thupi.
Izi zidatsimikiziridwa mwasayansi mu 2003. Asayansi ambiri amakhulupirira kuti lipoic acid imatha kugwiritsidwa ntchito pa matenda ashuga, omwe amayenda ndi kunenepa kwambiri.
Ndi zakudya ziti zomwe zimakhala ndi michere
Ngati munthu ali ndi matenda ashuga, ndiye kuti ayenera kutsatira kadyedwe. Zakudyazo ziyenera kukhala zakudya zomwe zili ndi mapuloteni komanso fiber. Komanso, ndizovomerezeka kudya zakudya zomwe zimakhala ndi lipoic acid.
Ngombe ya ng'ombe ili ndi michereyi. Kuphatikiza pa thioctic acid, ilinso ndi ma amino acid opindulitsa, mapuloteni komanso mafuta osapanga. Chiwindi cha ng'ombe ziyenera kudyedwa nthawi zonse, koma zochuluka. Tsiku lomwe simuyenera kudya magalamu 100 a izi.
More lipoic acid amapezeka mu:
- Chikhalidwe. Zakudya izi zimapezeka mu oatmeal, mpunga wamtchire, tirigu. Chofunika kwambiri cha chimanga ndi buckwheat. Muli kwambiri thioctic acid. Buckwheat alinso ndi mapuloteni ambiri.
- Ziphuphu. 100 magalamu a mphodza uli ndi pafupifupi 450-460 mg wa asidi. Pafupifupi 300-400 mg wa michere ili ndi magalamu 100 a nandolo kapena nyemba.
- Mitundu yatsopano. Gulu limodzi la sipinachi limakhala pafupifupi 160-200 mg ya lipoic acid.
- Mafuta opindika. Magalamu awiri amtunduwu ali ndi pafupifupi 10-20 mg ya thioctic acid.
Idyani zakudya zokhala ndi michereyi, ndizofunikira zochepa.
Kupanda kutero, kuchuluka kwa shuga m'magazi kumatha kukwera kwambiri.
Kukonzekera kwa Lipoic Acid
Ndi mankhwala ati omwe amaphatikiza lipoic acid? Izi ndi gawo la mankhwala monga Berlition, Lipamide, Neuroleptone, Thiolipone. Mtengo wa mankhwalawa sapitilira 650-700 oyendetsa. Mutha kugwiritsa ntchito mapiritsi okhala ndi lipoic acid a matenda ashuga, koma zisanachitike muyenera kufunsa dokotala.
Izi ndichifukwa choti munthu amene amamwa mankhwalawa angafunikire insulini yochepa. Zomwe zili pamwambapa zili ndi 300 mpaka 600 mg ya thioctic acid.
Kodi mankhwalawa amagwira ntchito bwanji? Awa mankhwala ndi ofanana. Mankhwala ali ndi tanthauzo loteteza maselo. Zinthu zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimateteza ma membala am'mimba ku zotsatira za magwiridwe anthawi.
Zisonyezero zogwiritsidwa ntchito kwa mankhwalawa zochokera ku lipoic acid ndi:
- Mellitus wosadalira insulin (mtundu wachiwiri).
- Insulin-wodwala matenda a shuga a mellitus (mtundu woyamba).
- Pancreatitis
- Matenda a chiwindi.
- Matenda a shuga a polyneuropathy.
- Kuwonongeka kwamafuta kwa chiwindi.
- Coronary atherosulinosis.
- Kulephera kwa chiwindi.
Berlition, Lipamide ndi mankhwala ochokera ku gawo ili amathandizira kuchepetsa thupi. Ndiye chifukwa chake mankhwalawa amatha kugwiritsidwa ntchito pochiza matenda amtundu wa 2 shuga, omwe amayamba chifukwa cha kunenepa kwambiri. Mankhwala amaloledwa kumwa panthawi yodyera kwambiri, monga kuchepetsa kuchepa kwa calorie okwana ma kilocalories 1000 patsiku.
Kodi ndingatenge bwanji alpha lipoic acid a matenda ashuga? Mlingo wa tsiku ndi tsiku ndi 300-600 mg. Mukamasankha mlingo, ndikofunikira kuganizira zaka za odwala komanso mtundu wa matenda ashuga. Ngati mankhwala omwe ali ndi lipoic acid amagwiritsidwa ntchito pochiza kunenepa kwambiri, mlingo wa tsiku ndi tsiku umachepetsedwa mpaka 100-200 mg. Kutalika kwa mankhwalawa nthawi zambiri mwezi umodzi.
Zotsatira zosagwiritsidwa ntchito ndi mankhwalawa:
- Nthawi yonyamula.
- Thupi lawo ndi thioctic acid.
- Mimba
- Zaka za ana (mpaka zaka 16).
Ndizofunikira kudziwa kuti mankhwalawa amathandizira kudziwa zambiri za insulin. Izi zikutanthauza kuti nthawi yamankhwala, mulingo wa insulin uyenera kusinthidwa.
Berlition ndi mawonekedwe ake sizikulimbikitsidwa kuti atengedwe limodzi ndi kukonzekera komwe kumakhala ndi zitsulo zazitsulo. Kupanda kutero, mphamvu ya mankhwalawo itha kuchepetsedwa.
Mukamagwiritsa ntchito mankhwala a lipoic acid, zotsatira zoyipa monga:
- Kutsegula m'mimba
- Kupweteka kwam'mimba.
- Mseru kapena kusanza.
- Minofu kukokana.
- Kuchulukitsa kwachulukira.
- Hypoglycemia. Woopsa, matenda a shuga amayamba. Zikachitika, wodwalayo ayenera kupatsidwa thandizo mwachangu. Ndikulimbikitsidwa kugwiritsa ntchito njira ya shuga kapena kuwaza ndi shuga.
- Mutu.
- Diplopia
- Spot zotupa.
Ngati mankhwala osokoneza bongo, thupi lawo siligwirizana angayambe, mpaka anaphylactic mantha. Pankhaniyi, ndikofunikira kutsuka m'mimba ndikumwa antihistamine.
Ndipo ndemanga zanji za mankhwalawa? Ogula ambiri amati lipoic acid imagwira ntchito m'matenda a shuga. Mankhwala omwe amapanga mankhwalawa athandiza kuyimitsa zizindikiro za matendawa.Anthu amanenanso kuti kugwiritsa ntchito mankhwalawa kumawonjezera nyonga.
Madokotala amathandizira Berlition, Lipamide ndi mankhwala ofananawo m'njira zosiyanasiyana. Ambiri a endocrinologists amakhulupirira kuti kugwiritsa ntchito lipoic acid kuli koyenera, chifukwa mankhwalawo amathandizira kuti magwiritsidwe ntchito a glucose agwire.
Koma madotolo ena ali ndi lingaliro kuti mankhwala ozikidwa pa chinthuchi ndi mtundu wamba.
Lipoic acid wamitsempha
Neuropathy ndi njira yomwe magwiridwe antchito amanjenje amasokonekera. Nthawi zambiri, matendawa amakula ndi matenda amtundu wa 2 komanso matenda a shuga. Madokotala amati ichi ndi chakuti matenda ashuga amasokoneza kayendedwe ka magazi ndikuwonjezera kuyipa kwa mitsempha.
Ndi minyewa ya m'magazi, munthu amayamba kumva kutupikana miyendo, mutu ndi kugwedezeka kwa dzanja. Kafukufuku wambiri wazachipatala adawulula kuti pakupitilira kwa zamatsenga zamtunduwu, ma radicals aulere amathandiza kwambiri.
Ichi ndichifukwa chake anthu ambiri omwe ali ndi vuto la matenda ashuga amawerengedwa kuti ndi acidic. Izi zimathandizira kukhazikika kwamanjenje, chifukwa chakuti ndi antioxidant wamphamvu. Komanso, mankhwala ozikidwa pa thioctic acid amathandizira kukonza zomwe zimayambitsa mitsempha.
Ngati munthu wadwala matenda a shuga, ndiye kuti ayenera:
- Idyani zakudya zomwe zimakhala ndi lipoic acid.
- Imwani mavitamini osakanikirana ndi mankhwala othandizira. Berlition ndi Tiolipon ndi angwiro.
- Nthawi ndi nthawi, asidi wa thioctic amathandizidwa kudzera m'mitsempha yamagazi (izi ziyenera kuchitika moyang'aniridwa ndi achipatala).
Kuchitidwa panthawi yake kumatha kuchepetsa mwayi wopita patsogolo kwa kudziyimira kwamitsempha yamagazi (matenda oyenda ndi matenda a mtima). Matendawa ndi amodzi mwa odwala matenda ashuga. Kanemayo munkhaniyi akupitiliza mutu wakugwiritsira ntchito asidi mu shuga.
Sonyezani shuga yanu kapena sankhani jenda kuti muyiyikire.
Matenda a shuga
Ndi matenda a shuga omwe akupita patsogolo komanso pang'onopang'ono akamakula m'magazi a shuga, mphamvu yamanjenje imawonongeka. Mavuto amayamba chifukwa cha kupangika kwa zinthu za glycolised zomwe zimakhudza misempha. Chifukwa cha kuchuluka kwa shuga m'magazi, kufalikira kwa magazi kumawonjezereka, chifukwa, kukonza minyewa kumachepa.
Kuzindikiritsidwa kwa matenda a diabetesic neuropathy kungachitike ngati pali zizindikiro zoyenera:
- kudumphira m'magazi,
- dzanzi la miyendo
- kumva m'miyendo, mikono,
- kupweteka
- chizungulire
- mavuto ndi erection mwa amuna
- mawonekedwe a kutentha kwadzuwa, kudzimbidwa, kukhumudwa kwambiri, ngakhale ndi chakudya chochepa chomwe chidadyedwa.
Kuti mupeze matenda olondola, ma reflexes amayendera, kuthamanga kwa mitsempha kumayesedwa, electromyograph imapangidwa. Mukatsimikizira neuropathy, mutha kuyesa kusintha matenda pogwiritsa ntchito α-lipoic acid.
Zosowa zathupi
Lipoic acid ndi mafuta acid. Ili ndi sulufule yambiri. Ndi madzi ndi madzi sungunuka, amatenga nawo mbali pakapangidwe ka cell membrane ndipo amateteza maselo a cell ku pathological zotsatira.
Lipic acid amatanthauza ma antioxidants omwe amatha kuletsa zotsatira za kusintha kwaulere. Amagwiritsidwa ntchito pochiza matenda ashuga a polyneuropathy. Katunduyo ndi wofunikira chifukwa:
- amatenga nawo mbali pakuchepa kwa shuga ndikuchotsa mphamvu,
- imateteza maselo a cell ku zotsatira zoyipa zama radicals aulere,
- ili ndi mphamvu ya insulin: imawonjezera zochitika zaonyamula shuga mu cytoplasm of cell, ikuthandizira njira yamatenda a glucose omwe amapangidwa ndi minofu,
- ndi antioxidant wamphamvu, wofanana ndi mavitamini E ndi C.
Ichi ndi chimodzi mwazinthu zabwino kwambiri zothandizira odwala matenda ashuga. Nthawi zambiri amalimbikitsa poika mankhwala okwanira. Amawerengedwa kuti ndi antioxidant wabwino, chifukwa asidi awa:
- odzipereka ku chakudya
- Amasinthidwa maselo kuti akhale omasuka,
- kawopsedwe kochepa
- ili ndi ntchito zosiyanasiyana zoteteza.
Mukamamwa, mutha kuthana ndi mavuto angapo omwe amadza chifukwa cha kuwonongeka kwa makulidwe amtundu wa oxidative.
Antioxidant wodziwika bwino, yemwe amadziwikanso kuti lipoic acid - mawonekedwe ogwiritsira ntchito shuga a mitundu yonse iwiri
Mankhwala, lipoic acid imamveka kuti imatanthawuza antioxidant wamkati.
Ikafika m'thupi, imawonjezera glycogen m'chiwindi ndikuchepetsa kuchuluka kwa shuga m'magazi am'magazi, imalimbikitsa kukana kwa insulin, imatenga gawo la matenda a carbohydrate ndi lipid metabolism, imakhala ndi hypoglycemic, hypocholesterolemic, hepatoprotective ndi hypolipidemic. Chifukwa cha mankhwalawa, lipoic acid nthawi zambiri amagwiritsidwa ntchito mtundu 1 komanso matenda ashuga a 2.
Vitamini N (kapena lipoic acid) ndi chinthu chomwe chimapezeka mu khungu lililonse m'thupi la munthu. Ili ndi mphamvu zambiri za antioxidant, kuphatikiza kuthekera m'malo mwa insulin. Chifukwa cha izi, vitamini N amaonedwa ngati chinthu chapadera chomwe chochita chake chimakhala chothandiza nthawi zonse.
Mthupi la munthu, asidiyu amatengapo mbali m'machitidwe amitundu mitundu, monga:
- mapangidwe mapuloteni
- kutembenuka kwa chakudya
- kapangidwe ka lipid
- mapangidwe ofunikira michere.
Chifukwa cha machulukidwe a lipoic (thioctic) acid, thupi limasungabe kwambiri glutathione, komanso mavitamini a gulu C ndi E.ads-mob-1
Kuphatikiza apo, sipadzakhala njala komanso kusowa kwa mphamvu m'maselo. Izi zimachitika chifukwa cha luso lapadera la asidi lomwe limayamwa glucose, lomwe limatsogolera kudzaza kwa ubongo ndi minofu ya munthu.
Mankhwala, pali milandu yambiri momwe Vitamin N amagwiritsidwa ntchito. Mwachitsanzo, ku Europe nthawi zambiri amagwiritsidwa ntchito pochiza matenda amitundu mitundu, mu mtundu uwu amachepetsa kuchuluka kwa jakisoni wofunika wa insulin. Chifukwa cha kukhalapo kwa antioxidant katundu mu vitamini N, thupi la munthu limalumikizana ndi ma antioxidants ena, zomwe zimapangitsa kutsika kwakukulu kwa chiwerengero cha ma radicals omasuka.
Thioctic acid imathandizira chiwindi, imalimbikitsa kuchotsa poizoni ndi zitsulo zolemera kuchokera m'maselo, imalimbitsa chitetezo chamthupi ndi chitetezo cha mthupi.
Vitamini N imakhala ndi mankhwala othandizira ku thupi osati mwa odwala matenda a shuga; imalembedwanso mwachangu matenda amitsempha, mwachitsanzo, ndi stroke ya ischemic (pankhaniyi, odwala amachira msanga, ntchito zawo zamaganizidwe zimayenda bwino, ndipo digiri ya paresis imachepetsedwa kwambiri).
Chifukwa cha zida za lipoic acid, zomwe sizimalola ma radicals aulere kudziunjikira m'thupi la munthu, zimateteza kwambiri ma membrane a cell ndi makoma a mtima. Ili ndi mphamvu yochizira pamatenda monga thrombophlebitis, mitsempha ya varicose ndi ena.
Anthu omwe amamwa mowa mopitirira muyeso amalangizidwanso kuti atenge lipoic acid. Mowa umakhudza maselo amitsempha, chifukwa chake amatha kuyambitsa mavuto ambiri machitidwe a metabolic. Ads-mob-2 ads-pc-2A vitamini N amathandizira kubwezeretsa.
Machitidwe omwe thioctic acid ali nawo mthupi:
- odana ndi yotupa
- immunomodulatory
- choleretic
- antispasmodic,
- radioprotective.
Mitundu yodziwika bwino ya shuga ndi iyi:
- Mtundu 1 - wodalira insulin
- Mtundu 2 - insulin yodziyimira payokha.
Pozindikira, munthuyu akusokoneza magwiritsidwe ntchito a glucose m'matumbo, ndipo kuti matenda azikhala ndi magazi, wodwalayo ayenera kumwa mankhwala osiyanasiyana, ndikutsatira zakudya zapadera, zomwe zimafunika kuti muchepetse kugwiritsidwa ntchito kwa chakudya.
Poterepa, alpha-lipoic acid wamtundu wa 2 shuga amalimbikitsidwa kuti aphatikizidwe muzakudya. Zimathandizira kukhazikika kwa dongosolo la endocrine ndipo limachepetsa shuga.
Thioctic acid imakhala ndi zinthu zambiri zothandiza m'thupi zomwe zimapangitsa kuti odwala matenda ashuga akhale:
- aphwanya mamolekyulu a shuga,
- ali ndi antioxidant
- kudya pafupipafupi kumalimbitsa chitetezo cha mthupi,
- kulimbana ndi zovuta zoyambitsa ma virus,
- amachepetsa kukwiya kwa poizoni pama cell cell.
Mu pharmacology, lipoic acid kukonzekera shuga imayimiriridwa kwambiri, mitengo ku Russia ndi mayina omwe akufotokozedwa mndandanda pansipa:
- Mapiritsi a Berlition - kuchokera 700 mpaka 850 ma ruble,
- Ziphuphu zakumaso - kuchokera ku ruble 500 mpaka 1000,
- Mapiritsi a Tiogamm - kuchokera ku 880 mpaka ma ruble 200,
- Thiogamm ampoules - kuchokera ku ruble 220 mpaka 2140,
- Alpha Lipoic Acid Makapaseti - kuchokera 700 mpaka 800 ma ruble,
- Makapisozi a Oktolipen - kuchokera ku ruble 250 mpaka 370,
- Mapiritsi a Oktolipen - kuchokera ku ruble 540 mpaka 750,
- Oktolipen ampoules - kuchokera 355 mpaka 470 rubles,
- Mapiritsi a Lipoic acid - kuchokera 35 mpaka 50 ma ruble,
- Neuro lipene ampoules - kuyambira 170 mpaka 300 rubles,
- Makapisozi a Neurolipene - kuchokera ku ruble 230 mpaka 300,
- Thioctacid 600 T ampoule - kuyambira 1400 mpaka 1650 rubles,
- Mapiritsi a Thioctacid BV - kuyambira 1600 mpaka 3200 rubles,
- Mapiritsi a Espa lipon - kuyambira 645 mpaka 700 rubles,
- Espa lipon ampoules - kuyambira 730 mpaka 800 rubles,
- Tialepta Mapiritsi - kuchokera 300 mpaka 930 rubles.
Lipoic acid nthawi zambiri amagwiritsidwa ntchito popanga mankhwala ngati chinthu chowonjezera, kapena amagwiritsidwa ntchito ngati chida chachikulu pothana ndi matendawa: matenda ashuga, neuropathy, atherosclerosis, myocardial dystrophy, matenda a kutopa kwambiri.
Ziphuphu zakumaso
Nthawi zambiri amalembedwa mokwanira zokwanira (kuchokera 300 mpaka 600 milligrams patsiku). Woopsa matendawa, kukonzekera zochokera thioctic acid kutumikiridwa m`nsinga masiku khumi ndi anayi.
Kutengera ndi zotsatira zake, chithandizo china chokhala ndi mapiritsi ndi makapisozi, kapena maphunziro owonjezera a masabata awiri amatha kutumikiridwa. Mlingo wokonza nthawi zambiri umakhala wama milligram 300 patsiku. Ndi nthenda yofatsa yamatenda, Vitamini N amakhazikitsidwa nthawi yomweyo monga mapiritsi kapena makapisozi. Ads-mob-1 ads-pc-4Mitsempha, asidi wa lipoic amayenera kuperekedwa kwa ma 300-600 mamililita pa maola 24, omwe amafanana ndi ampoules amodzi kapena awiri.
Pankhaniyi, ayenera kuchepetsedwa mu saline yachilengedwe. Mlingo wa tsiku ndi tsiku umathandizidwa ndi kulowetsedwa kamodzi.
Mwanjira yam'mapiritsi ndi makapisozi, mankhwalawa amalimbikitsidwa kuti amwe mphindi 30 asanadye, pomwe mankhwalawa amayenera kutsukidwa ndi madzi okwanira.
Nthawi yomweyo, ndikofunikira kuti musalire ndi kutafuna mankhwalawa, mankhwalawo amayenera kumwa wonse. Mlingo watsiku ndi tsiku umasiyana kuchokera pa 300 mpaka 600 milligram, omwe amagwiritsidwa ntchito kamodzi.
Kutalika kwa mankhwalawa kumangoperekedwa ndi adokotala okha, koma makamaka ndi masiku 14 mpaka 28, pomwe mankhwalawa angagwiritsidwe ntchito pokonzanso mlingo wa 300 milligrams kwa masiku 60.
Palibe milandu yovuta chifukwa chakumwa kwa thioctic acid, koma ndimavuto panthawi yomwe thupi limamenyedwa ndi thupi, mavuto osiyanasiyana akhoza kubuka:
- vuto la chiwindi
- kudzikundikira kwamafuta
- kuphwanya kapangidwe ka bile,
- atherosulinotic madongosolo mumatumba.
Mankhwala okhala ndi vitamini N ndi ovuta kupeza, chifukwa amachotsedwa msanga m'thupi.
Mukamadya zakudya zomwe zimakhala ndi lipoic acid, ndizosatheka kupeza bongo wambiri.
Ndi jakisoni wa vitamini C, milandu ingachitike ndi:
- osiyanasiyana thupi lawo siligwirizana
- kutentha kwa mtima
- kupweteka pamimba,
- kuchuluka acidity m'mimba.
Kodi lipic acid yothandiza ndi iti? Momwe mungamwe mankhwalawa? Mayankho mu kanema:
Lipoic acid ili ndi zabwino zambiri komanso zowerengeka zochepa, chifukwa chake kugwiritsidwa ntchito kumalimbikitsidwa osati pamaso pa matenda aliwonse, komanso pofuna kupewa. Nthawi zambiri, amalembedwa mothandizidwa ndi matenda ashuga, pomwe amachita imodzi mwamagawo. Zochita zake zimayambitsa kutsika kwa glucose wamagazi ndikuwongolera bwino chifukwa cha kuchuluka kwa zotsatira.
- Imakhazikika pamisempha ya shuga kwa nthawi yayitali
- Imabwezeretsa kapangidwe ka insulin
Kugwiritsa ntchito lipoic acid mu shuga ndi imodzi mwazinthu zodziwika bwino za mankhwala ovuta. Kuchita bwino kwa njirayi kwatsimikiziridwa ndi maphunziro angapo omwe achitidwa kuyambira 1900. Malinga ndi zotsatira za kafukufukuyu, zidatsimikiziridwa kuti lipoic acid ndi njira yothandiza komanso yothandizirana pochiza matendawa.
Lipoic acid adachotsedwa ku chiwindi cha bovine mu 1950. Kapangidwe kake ka mankhwala kumawonetsa kuti ndi acid acid ndi sulfure yomwe ili m'maselo a thupi la munthu. Izi zikutanthauza kuti asidiyu amatha kusungunuka m'malo osiyanasiyana - madzi, mafuta, acid acid. Ndi bwino kukhala wathanzi, chifukwa:
- Acid iyi imachita mbali yayikulu mu kagayidwe, monga pokonza glucose mu mphamvu yogwiritsidwa ntchito ndi thupi.
- Mankhwalawa amadziwika kuti ndi antioxidant wamphamvu kwambiri (selenium, vitamini E, ndi zina), amene amatseka zinthu zoyipa zomwe zimatchedwa free radicals. Poyamba, poganizira kufunika kwakukulu munjira zosiyanasiyana, asidiyu amatchulidwa ngati vitamini wa gulu B. Koma sakuphatikizidwanso m'gululi.
- Zimatulutsa zotsatira zomwe zili zofanana ndi zomwe zimachitika insulin. Imathandizira njira ya kulolera kwa shuga mu cell ndikusintha mayamwidwe a glucose ndi minofu.
Bweretsani ku zomwe zalembedwa
Chimodzi mwazomwe chimayambitsa matendawa kuyambika komanso zovuta zomwe zimachitika ndikuphwanya kapangidwe ka maselo a pancreatic β-ma mawonekedwe a hyperglycemia (kuchuluka kwa glucose). Kusintha kwa mulingo wa asidi-acid kumachitika, komwe kumabweretsa kuwonongeka mumapangidwe amitsempha yamagazi ndi zotsatira zina.
Alpha lipoic acid mu shuga amatha kuletsa izi. Popeza mankhwalawa samatha kusungunuka, umagwira m'mbali zonse za thupi. Ma antioxidants otsala alibe mphamvu, chifukwa chachikulu chomwe mankhwalawa amapanga mu shuga ndi chakuti ndi antioxidant wamphamvu. Amagwiritsa ntchito mfundo iyi:
Ntchito za a-lipoic acid mthupi komanso momwe zimakhudzira chitukuko cha matenda ashuga.
- Pali cholepheretsa ma free radicals opangidwa m'thupi nthawi ya kuwonongeka kwa lipid.
- Imagwira ntchito pakati pa antioxidants, kuwapangitsa kuti achitenso kanthu.
- Choyeretsa thupi la zinthu zapoizoni, ndikuchichotsa mu izo.
- Imachepetsa kuchuluka kwa pH kuzunza ma membrane a ma cell.
Bweretsani ku zomwe zalembedwa
- Kulimbitsa chitetezo chokwanira, kukulitsa kukana kwa thupi kumatenda osiyanasiyana.
- Kutsitsa shuga.
- Kuchepetsa kuthekera kwa matendawo.
- Kupititsa patsogolo thanzi la munthu, kubweretsa thupi.
Malinga ndi zomwe apezeka, akutiicic acid amagwira ntchito bwino kwambiri ndi matenda a shuga a 2 kuposa okhala ndi matenda ashuga a mtundu woyamba. Izi ndichifukwa chakuti asidi amachepetsa misempha ya shuga popereka chitetezo cha pancreatic β-cell. Zotsatira zake, minofu kukana insulin yafupika.
Malangizo ogwiritsira ntchito lipoic acid mu shuga
Mankhwalawa amapezeka mu mawonekedwe a mapiritsi ndi mapiritsi a 100, 200, 600 mg.), Ampoules yankho la jakisoni mu mtsempha mulinso. Koma nthawi zambiri amamwa mankhwalawa pakamwa. Mlingo wa tsiku ndi tsiku ndi 600 mg., Waledzera katatu patsiku kwa mphindi 60. musanadye kapena pambuyo pa mphindi 120. pambuyo.Kumwa mankhwalawa osavomerezeka ndi zakudya, chifukwa kumamwa kwambiri.
- Hypersensitivity mankhwala.
- Zaka mpaka 6.
- Nthawi yapakati.
Bweretsani ku zomwe zalembedwa
Mankhwala a Acid komanso mankhwala osokoneza bongo amatha kuyambitsa zovuta izi: nseru, kusanza, mutu, kufooka, masoka, (chithunzi chosachita bwino), kutsika kwamwazi wamagazi, komanso kuperewera kwa magazi. Zotsatira zonse zosayenerera zimafotokozedwa mosamala mu malangizo ogwiritsira ntchito. Kwenikweni, mankhwala omwe ali ndi lipoic acid pazomwe zimapangidwa amaloledwa bwino ndi thupi.
Lipoic acid ndi chinthu chomwe chimachepetsa kubereka oxidation.
Palibe gawo limodzi lama metabolic mthupi lomwe limakhala lathunthu popanda iwo.
Zakudya zambiri zimakhala ndi antioxidant wachilengedwe.
Anthu omwe ali ndi matenda a shuga amalimbikitsidwa kuti atenge lipoic acid kuwonjezera apo, mwa njira zowonjezera zamankhwala.
Endocrinologist ithandizanso kumvetsetsa zomwe zimachitika pakumwa izi, komanso nthawi yanthawi yamankhwala.
Lipoic kapena thioctic acid (vitamini N) ndi gawo lofunikira la maselo. Popanda iyo, palibe njira yosinthira yomwe ingachitike. Pali amakonzekera ambiri a zamankhwala opangidwa pamaziko ake. Mankhwalawa amagwiritsidwa ntchito pochiza matenda ashuga.
Ubwino wa lipoic acid:
- chofunikira pakugawa molekyu ya glucose m'maselo,
- Vitamini N akutenga nawo mbali popanga ufulu wa ATP,
- antioxidant achilengedwe, amachepetsa njira zama oxidative,
- kukhazikitsa chitetezo chathupi,
- mavitamini N ali ofanana ndi insulin,
- thioctic acid - wothandizira,
- imabwezeretsa ndikuyambitsa ma antioxidants ena a ma cell,
- amachepetsa mavuto obwera chifukwa cha zoopsa zachilengedwe.
- imagwira ntchito ngati poyizoni poizoni.
Kafukufuku wa zamankhwala awonetsa kuti thioctic acid imachulukitsa kuzindikira kwa ma cell kwa pancreatic hormone - insulin. Matenda a mtundu wa Vitamini N amatithandizira kuchepa.
Makalata ochokera kwa Owerenga
Agogo anga akhala akudwala matenda a shuga kwa nthawi yayitali (mtundu 2), koma posachedwapa mavuto atuluka pamiyendo ndi ziwalo zamkati.
Mwangozi ndidapeza nkhani pa intaneti yomwe idapulumutsa moyo wanga. Zinali zovuta kuti ndione chizunzo, ndipo fungo loipa m'chipindacho linali kundiyambitsa misala.
Kupyola nthawi ya chithandizo, agogo aja adasinthanso momwe akumvera. Ananenanso kuti miyendo yake sikupweteka komanso zilonda zake sizinayende; sabata yamawa tidzapita ku ofesi ya dotolo. Falitsa ulalo wa nkhaniyo
Kwa odwala omwe ali ndi matenda ashuga, lipoic acid imagwiritsidwa ntchito ngati gawo lofunikira la zovuta mankhwala. Kukula kwa matendawa kumayendera limodzi ndi kuwonongeka kwa minyewa yam'mimba chifukwa cha kukhathamiritsa kwa oxidation ambiri. Mwazi wamagazi m'magazi amachititsa izi, ndipo wodwalayo akuipiraipira.
Lipoic acid amagwiritsidwa ntchito pochiza matenda onse a shuga. Amatchulidwa ngati mankhwala othandizira komanso ngati prophylactic. Vitamini N imayambitsa njira zama cell zomwe zimatha kuthamangitsa shuga, chifukwa chomwe ndende yake m'magazi imachepa.
Thioctic acid imachulukitsa ma cell insulin. Koma simungathe kuzigwiritsa ntchito m'malo mwa mahomoni, chifukwa mphamvu ya asidi ndiyofooka.
Momwe mungasungire shuga kukhala wabwinobwino mu 2019
Kuphatikiza pa matenda ashuga, lipoic acid imagwiritsidwa ntchito pochiza zovuta zosiyanasiyana zomwe zimabuka motsutsana ndi maziko a matenda awa.
Mavuto a shuga pa matenda omwe thioctic acid imagwiritsidwa ntchito:
Pochizira ma pathologies awa, jakisoni wothandizidwa amagwiritsidwa ntchito, omwe amatha kukonza bwino mkhalidwe wa wodwalayo.
M'masamba ogulitsa mankhwala, mutha kugula mankhwala a lipoic acid. Amapezeka ndikugulitsa komanso kugawidwa popanda kutsatira kwa dokotala. Ndikosatheka kusintha mankhwala opangira ndi zakudya, chifukwa lipoic acid samumwa bwino kwambiri kuchokera ku chakudya.
Mankhwala odziwika a thioctic acid:
Malamulo a lipoic acid amatsimikiziridwa ndi mawonekedwe a kumasulidwa kwa mankhwalawa. Monga prophylaxis, thioctic acid imatengedwa pamapiritsi. Mlingo wambiri watsiku ndi tsiku sayenera kupitirira 600 mg. Mutha kumwa mapiritsi kamodzi (600 mg) kapena kawiri pa tsiku (300 mg), m'mawa pamimba yopanda kanthu. Dongosolo lotere limathandiza kupewa zovuta zomwe zimadza ndi matenda ashuga.
Ngati lipoic acid imayikidwa pochiza matenda a pathologies, ndiye kuti njira zomwe zimayenera kuperekedwa kudzera m'mitsetse zimagwiritsidwa ntchito. Malowa ndi oyenera kuthandizira odwala matenda ashuga.
Simungasankhe mwayekha mlingo wa mankhwala ndi mulingo wa mankhwalawo. Izi zimatsimikiziridwa ndi dokotala potengera kuopsa kwa matendawa.
Palibe zochitika zolembedwa za bongo mopitirira muyeso kapena kupezeka kwa zovuta zamankhwala. Koma kuthekera kwa kuchitika kwawo kulipo.
Zotheka kuchitidwa:
Timapereka kuchotsera kwa owerenga tsamba lathu!
- kusokoneza chiwindi,
- kuchuluka kwa adipose minofu
- kusayenda kwa ndulu ndi kuperewera kwake kosakwanira mu ndulu,
- kusintha kwa mitsempha yamitsempha yamagazi,
- chopondapo tulo mu mawonekedwe a kutsegula m'mimba kapena kudzimbidwa,
- kumva mseru ndi kusanza,
- kupweteka m'mimba
- mwendo kukokana
- mutu wovuta, migraine,
- kuchuluka kwamphamvu zakunkhondo,
- kuchepa kwakukulu kwa ndende ya magazi ndi kukula kwa hypoglycemia,
- kuwonongeka kowoneka, komwe kumadziwoneka ngati gawo logawanika la zinthu,
- kupindika kwamitsempha yamagazi ndi zotupa.
Ngati muli ndi zizindikiro zotere mwa kumwa mankhwala a lepic acid, muyenera kufunsa dokotala ndipo musiyeni kumwa mankhwalawo.
Zotsatira zoyipa zimatha kuchitika chifukwa chosakonzekera bwino mankhwalawa ndikuphwanya malangizo a katswiri. Chifukwa chake, simungasinthe mwaulere mlingo komanso mankhwala.
Kukonzekera kwa asidi wa Lipoic sikuyenera kutengedwa pazotsatirazi:
- Nthawi yonyamula mkaka
- kupezeka kwa thupi lawo siligwirizana ndi zigawo zikuluzikulu za mankhwala,
- nthawi yobala mwana,
- ana osakwana zaka 16.
Mankhwala a lipoic acid omwe ali ndi insulin yodalira matenda a shuga, ndikofunikira kusintha kuchuluka kwa jakisoni wa mahomoni. Izi ndichifukwa choti kuphatikiza kwa insulin ndi thioctic acid kumayambitsa hypoglycemia.
Thioctic acid amapangidwa ndi hepatocytes a chiwindi. Kuti izi zitheke, ndikofunikira kuti zigawo zomwe zimapanga asidi zizilowa mthupi ndi chakudya.
Zakudya momwe mumakhala mankhwala a lipoic acid ambiri:
- nkhuku, nyama ya kalulu, nkhuku ndi mitundu ina ya nyama "yoyera",
- kabichi wa broccoli
- masamba sipinachi
- nandolo zobiriwira
- tomato
- Brussels imamera
- ng'ombe
- ng'ombe chiwindi
- wolakwa,
- mazira
- zopangidwa mkaka - kirimu wowawasa kapena kefir,
- kabichi yoyera
- mkuyu.
Kudya tsiku lililonse kuchokera pamndandandawu kungathandize kukwaniritsa kufunika kwa thupi kwa lipoic acid. Tiyenera kudziwa kuti chinthu ichi chimamwitsidwa bwino ndi chakudya.
Matenda a shuga amapezeka pafupifupi zaka 10 zapitazo. Zaka zoyambirira zinali mtundu 2, koma m'kupita kwa nthawi, zidasinthidwa kukhala mawonekedwe odalira insulin. Dokotala wothandizirana ndi mankhwalawa adayankhidwa kuti akonzekere mankhwala a polelo. Poganizira zakudya kwake, ndidawona kusintha pang'ono. Pambuyo pakutha kwa njira yakuwonongeka sikunatsatire.
Alexander, wazaka 44.
Ndili ndi matenda ashuga a 2. Ndakhala ndikumwa lipic acid kwa chaka chimodzi monga momwe adanenera dokotala. Ndili wokondwa kwambiri ndi chida ichi, chifukwa Kwa nthawi yayitali, kugwiritsidwa ntchito kwa glucose kumakhala kosungidwa mwa malire oyenera, ndipo thanzi limakhala labwino.
Christina, wazaka 27.
Anandiika lipoic acid ngati jekeseni wochizira matenda a shuga. Zinthu zinafika pobwerera. Kuchiza kumabweretsa zotsatira zabwino.
Svetlana, wazaka 56.
Lipoic acid ndi njira yotithandizira kusintha kagayidwe kazakudya, kamene kanali ndi vuto chifukwa cha matenda ashuga. Maselo amtundu wa Vitamini N amakhala otengeka kwambiri ndi zochita za mahomoni a kapamba. Lipoic acid umagwiritsidwa ntchito pa zovuta za matenda a shuga ndi zovuta zake. Odwala ambiri amafotokoza zotsatira zabwino pamene akumwa mankhwala a acid.
Matenda a shuga nthawi zonse amayambitsa zovuta zakupha. Mwazi wamagazi ochulukirapo ndi woopsa kwambiri.
A Alexander Myasnikov mu Disembala 2018 adapereka chidziwitso chokhudza chithandizo cha matenda ashuga. Werengani kwathunthu
Perekrest S.V., Shainidze K.Z., Korneva E.A. Kachitidwe ka mitsempha yama orexin. Mapangidwe ndi ntchito, ELBI-SPb - M., 2012. - 80 p.
Davidenkova, E.F. Genetics ya matenda a shuga a mellitus / E.F. Davidenkova, I.S. Lieberman. - M: Mankhwala, 1988 .-- 160 p.
Alexander, Kholopov und Yuri Pavlov Kukhathamiritsa kwa unamwino kwa odwala matenda ashuga phokoso / Alexander Kholopov und Yuri Pavlov. - M: LAP Lambert Academic Publishing, 2013 .-- 192 p.- Bobrovich, P.V. Mitundu yamagazi 4 - njira 4 kuchokera ku matenda ashuga / P.V. Bobrovich. - M: Potpourri, 2003 .-- 192 p.
Ndiloleni ndidziwitse. Dzina langa ndi Elena. Ndakhala ndikugwira ntchito ya endocrinologist kwa zaka zoposa 10. Ndikukhulupirira kuti pakadali pano ndili katswiri pantchito yanga ndipo ndikufuna kuthandiza alendo onse omwe amapezeka pamalowo kuti athetse zovuta osati ntchito. Zinthu zonse za tsambalo amazisonkhanitsa ndikuzikonza mosamala kuti athe kufotokoza zambiri zofunikira. Musanagwiritse ntchito zomwe zikufotokozedwa pa webusayiti, kukambirana ndi akatswiri ndizofunikira nthawi zonse.
Zotsatira pa thupi la odwala matenda ashuga
Mthupi, thioctic acid imagwira ntchito zotsatirazi:
- imalepheretsa zowopsa zaulere zamagetsi ndikuisokoneza njira ya makutidwe ndi okosijeni,
- imabwezeretsa ndikupangitsa kuti igwiritsenso ntchito antioxidants amkati: mavitamini C, E, coenzyme Q10, glutathione,
- chimamangirira zitsulo zakumwa zoziziritsa kukhosi ndikuchepetsa kupanga ma free radicals.
Asidi omwe atchulidwa ndi gawo limodzi lachitetezo cha thupi. Chifukwa cha ntchito yake, ma antioxidants ena amabwezeretsedwa, atha kutenga nawo gawo mu kagayidwe ka nthawi yayitali.
Malinga ndi dongosolo la biochemical, chinthu ichi ndi chofanana ndi mavitamini a B. Mu 80-90s ya zaka zapitazi, asidi awa amatchedwa mavitamini a B, koma njira zamakono zapangitsa kuti amvetsetse kuti ili ndi mitundu yosiyanasiyana ya biochemical.
Acid imapezeka mu ma enzymes omwe amathandizira kukonza zakudya. Ikapangidwa ndi thupi, kuchuluka kwa shuga kumachepa, ndipo ndizofunikira kwambiri kwa odwala matenda ashuga.
Chifukwa cha antioxidant zotsatira ndi kumangika kwa ma radicals aulere, zovuta zawo pazovuta zimalepheretsedwa. Thupi limachepetsa kukalamba ndipo limachepetsa kupsinjika kwa oxidative.
Acid iyi imapangidwa ndi minofu ya chiwindi. Amapangidwa kuchokera ku chakudya chomwe chikubwera. Kuti muwonjezere kuchuluka kwake, tikulimbikitsidwa kugwiritsa ntchito:
- nyama yoyera
- broccoli
- sipinachi
- nandolo zobiriwira
- Tomato
- Brussels imamera
- mpunga.
Koma pazinthu, izi zimagwirizanitsidwa ndi amino acid a mapuloteni (ndiwo, lysine). Ili ndi mtundu wa R-lipoic acid. Kuchulukitsa kwakukulu, antioxidant iyi imapezeka mu ziwalo za nyama zomwe zimagwira ntchito kwambiri. Kuzungulira kwakukulu, kumatha kupezeka impso, chiwindi ndi mtima.
Pokonzekera thioctic acid, imaphatikizidwa mwaulere mawonekedwe. Izi zikutanthauza kuti sizimagwirizana ndi mapuloteni. Mukamagwiritsa ntchito mankhwala apadera, kuchuluka kwa asidi m'thupi kumawonjezera nthawi 1000. Ndikosatheka kupeza 600 mg pazinthu izi kuchokera ku chakudya.
Akonzekereratu kukonzekera kwa lipoic acid a shuga:
Musanagule chinthu, funsani ndi dokotala.
Therapy regimen kusankha
Popeza mwasankha kusintha magwiritsidwe a shuga ndi ziwalo ndi machitidwe mothandizidwa ndi lipoic acid, muyenera kumvetsetsa dongosolo la kudya. Zinthu zina zimapezeka mwanjira ya mapiritsi kapena makapisozi, zina mwa njira yothetsera kulowetsedwa.
Pazifukwa zodzitetezera, mankhwalawa amatchulidwa ngati mapiritsi kapena mapiritsi. Iwo aledzera katatu patsiku kwa 100-200 mg. Ngati mumagula mankhwalawa muyezo wa 600 mg, ndiye kuti mlingo umodzi patsiku uzikhala wokwanira. Mukamamwa zowonjezera ndi R-lipoic acid, ndikokwanira kumwa 100 mg kawiri patsiku.
Kugwiritsa ntchito mankhwala molingana ndi chiwembuchi kungalepheretse zovuta za matenda ashuga. Koma muyenera kumwa mankhwalawa kokha pamimba yopanda kanthu - ola limodzi musanadye.
Mothandizidwa ndi asidi, mutha kuyesa kuchepetsa kuwonetsa kwa zovuta monga matenda a shuga. Koma chifukwa cha izi, kayendetsedwe ka intravenous mu mawonekedwe a njira zapadera m'malo ambiri kwanthawi yayitali.
Izi zimaphatikizidwa pakuphatikizidwa kwa ma multivitamini ena mpaka 50 mg. Koma kukwaniritsa zabwino pa thupi la munthu wodwala matenda ashuga komanso kudya acid mu Mlingo woterewu ndizosatheka.
Kusankha mitundu ya mankhwala
Mothandizidwa ndi pakamwa pa cy-lipoic acid, kuphatikiza kwakukulu kumawonedwa pambuyo pa mphindi 30-60. Amatengeka mwachangu m'magazi, koma amathandizidwanso mwachangu. Chifukwa chake, mukamamwa mapiritsi, kuchuluka kwa shuga kumakhala kosasinthika. Kuzindikira kwa minofu kupita ku insulin kumawonjezeka pang'ono.
Ndi mlingo umodzi wa 200 mg, bioavailability wake ali pamlingo wa 30%. Ngakhale ndi chithandizo chopitilira masiku ambiri, chinthu ichi sichimadziunjikira m'magazi. Chifukwa chake, kuudya pofuna kuthana ndi kuchuluka kwa glucose ndikosatheka.
Ndi kukhuthala kwa mankhwalawa, mlingo wofunikira umalowa m'thupi mkati mwa mphindi 40. Chifukwa chake, ntchito yake imachulukitsidwa. Koma ngati chiphuphu cha matenda a shuga sichingatheke, ndiye kuti zilembo za matenda ashuga zidzabweza pakapita nthawi.
Anthu ena amalimbikitsa kumwa mapiritsi a zakudya a lipoic acid. Kupatula apo, amatenga nawo gawo pama metabolism a mafuta ndi mafuta. Koma ngati simutsatira mfundo zachakudya zoyenera, kukana masewera olimbitsa thupi, kusiya kulemera mopitirira muyeso ndimamwa mapiritsi sikugwira ntchito.
Zoyipa za chida
Kukonzekera mankhwala a thioctic acid nthawi zina kumachitika limodzi ndi kukonzekera zotsatira zoyipa:
- mavuto a dyspeptic
- mutu
- kufooka.
Koma amawoneka, monga lamulo, ndi mankhwala osokoneza bongo.
Odwala ambiri amayembekeza kuti athetse matenda a shuga pomwa mankhwalawa. Koma kukwaniritsa izi ndizosatheka. Kupatula apo, siziunjikira, koma imakhala ndi nthawi yochepa yochizira.
Monga gawo la zovuta mankhwala, endocrinologist angalimbikitse kugwiritsa ntchito lipoic acid kwa odwala matenda ashuga. Chida ichi ndi antioxidant, chimachepetsa zovuta zoyipa zama radicals omasuka m'thupi.
Alpha lipoic acid ndi udindo wake m'thupi
Katunduyo adayamba kudzipatula ku chiwindi cha ng'ombe mu 1950. Kenako zidaganiziridwa kuti chinthucho chitha kukhala ndi tanthauzo pabwino la mapuloteni m'thupi. Tsopano ndikudziwika kuti ali m'gulu la acid acid ndipo ali ndi sulufuzi wophatikizika.
Kapangidwe kofananako kamatsimikiza kuthekera kwake kusungunuka m'madzi ndi mafuta. Amatenga nawo gawo popanga maselo a ma cell, amawateteza ku zotsatira za pathological.
Lipoic acid wa matenda ashuga ndiwofunika kwambiri chifukwa ali ndi zotsatirazi zochiritsa:
- Amatenga nawo gawo lakuwonongeka kwa mamolekyulu a shuga, ndikutsatira kapangidwe ka mphamvu ya ATP.
- Ndi amodzi mwa ma antioxidants achilengedwe amphamvu kwambiri limodzi ndi vit. C ndi E. Mu 1980-1990s, idaphatikizidwa ndi kuchuluka kwa mavitamini a B, koma maphunziro owonjezerawa adapangitsa kuti pakhale zovuta zomwe zimapangidwira mankhwala.
- Chimateteza maselo amthupi ku ma free radicals.
- Ili ndi katundu wofanana ndi insulin.Zimawonjezera ntchito zaomwe zimanyamula shuga mkati mwa cytoplasm ndipo zimathandizira kuti shuga ayende bwino ndi minofu. Zachidziwikire, kuopsa kwa izi ndizotsika kwambiri kuposa zomwe zimachitika pancreatic hormone, koma izi zimaloleza kuphatikizidwa ndi zovuta za mankhwalawa pochiza matenda a shuga.
Chifukwa cha mawonekedwe ake, asidi wa lipoic (thioctic) tsopano akulimbikitsidwa kukhala imodzi mwazipangizo zofunikira kwambiri. Akatswiri ena asayansi amati ndikofunika kuudya kuposa mafuta am'madzi.
Kodi asidi amagwira ntchito bwanji m'matenda a shuga?
Cholinga chachikulu cha mankhwalawa chimakhalabe ndi antioxidant. Amadziwika kuti chimodzi mwazomwe zimayambitsa matenda ashuga komanso zovuta zake ndikuwonongeka kwa maselo a pancreatic B ndikuchitika kwa hyperglycemia. Kusintha kwa acid ndi pH kupita ku mbali ya acidic kumabweretsa kuwonongeka kwa mitsempha yamagazi, zimakhala ndi mapangidwe a neuropathy, retinopathy, nephropathy ndi zotsatira zina.
Chithandizo cha matenda osokoneza bongo a mellitus omwe ali ndi lipoic acid amathandizira pakuwunika m'njira zonsezi. Popeza mankhwalawa amasungunuka mumtundu uliwonse (wamafuta ndi madzi), ntchito yake imawonekera m'malo onse a thupi. Ma antioxidants apamwamba sangathe kudzitamandira m'njira zosiyanasiyana ngati izi.
Matenda a shuga ndi zakudya zachilengedwe zomwe sizimagwiritsidwa ntchito masiku onse (zopatsa) zochokera ku Fucus zamadzi amchere, zopangidwa ndi mabungwe asayansi aku Russia, zofunikira kwambiri pakudya komanso zakudya za odwala omwe ali ndi matenda a shuga, akulu ndi achinyamata omwe. Zambiri.
Thioctic acid imagwira ntchito motengera izi:
- Imathandizira mafayilo amtundu waulere omwe amapangidwa m'thupi nthawi ya lipid peroxidation.
- Amabwezeretsa kale antioxidants amkati (glutatiton, ascorbic acid, tocopherol) kuti agwiritsenso ntchito.
- Amamangirira zitsulo zolemera ndi zinthu zina zapoizoni mu ma chelating ma cell, kuwachotsa m'thupi mwa njira yotetezeka.
- Imachepetsa kukwiya kwa pH pamitsempha yama cell.
Chifukwa chake, pambuyo pakupereka mankhwala pafupipafupi, zotsatirazi zitha kuyembekezeredwa:
- Kuchulukana kwa thupi kumatenda a bacteria komanso bacteria.
- Kuchepetsa shuga ya seramu poteteza ma cell a pancreatic B ndikuchepetsa kukana kwa zotumphukira kwa insulin. Ichi ndichifukwa chake lipoic acid wochokera ku mtundu wachiwiri wa shuga amawonetsa zotsatira zabwino kuposa mtundu woyamba wa matendawa.
- Kuchepetsa chiwopsezo cha zovuta (zotupa za ma nephrons, retina ndi malekezero ang'onoting'ono amitsempha).
- Kusintha kwakukulu mu wodwala. Kubweretsa thupi lake.
Momwe mungamwe mankhwalawo?
Kugwiritsa ntchito lipoic acid ku matenda a shuga sikungakhale kopambanitsa. Mankhwala omwe amapezeka kwambiri mwa mapiritsi kapena mapiritsi okhala ndi 100, 200, 600 mg. Pali jakisoni wambiri wokapanda kuleka. Pakadali pano, palibe umboni uliwonse womwe ungafotokozere motsimikiza njira ina yogwiritsira ntchito.
Pankhani imeneyi, odwala ndi madokotala amakonda njira yoyankhulira pakamwa. Mlingo wovomerezeka tsiku lililonse ndi 600 mg. Mutha kumwa tabu 1. m'mawa kapena atatu Mlingo tsiku lonse. Zonse zimatengera zomwe wodwala amakonda.
Ndikofunika kudziwa kuti lipoic acid imataya gawo la chakudya chake pakudya. Chifukwa chake, ndikofunikira kugwiritsa ntchito ola limodzi musanadye kapena 2 mutatha kudya. Poterepa, mlingo wonse umayamwa bwino ndi thupi.
Zovuta ndi zoyipa zimachitika
Zoyipa zazikulu za mankhwalawa ndi izi:
- Mtengo wokwera. Mlingo watsiku ndi tsiku wa mankhwalawa ndi pafupifupi $ 0,3.
- Matumba ambiri mumsika woweta. Sizachisoni, koma chifukwa chotchuka kwambiri cha thioctic acid, opanga ambiri amagulitsa malonda otsika mtengo. Chifukwa chake, njira yabwino ikhoza kukhala yoyitanitsa ku United States. Mtengo si wosiyana, koma zotsatira zake zimakhala bwino kwambiri.
Mankhwalawa amathandizidwa ndi odwala ndipo palibe mavuto omwe amawonedwa.
Zotsatira zosafunikira zingakhale:
Komabe, palibe milandu yotere yomwe sinalembetsedwe ndi mlingo wokwanira. Musanayambe mankhwala a lipoic acid, muyenera kufunsa dokotala.
Malangizo & zidule
Zambiri
OCHITSA AMBUYE! Ndi chida chapadera ichi, mutha kuthana ndi shuga ndikukhala ndi moyo mpaka kukalamba. Kawiri kudwala matenda ashuga!
Vutoli linapezeka chapakati pa zaka za m'ma 1900 ndipo limawonedwa ngati bacterium wamba. Kafukufuku wosamala adawonetsera kuti lipoic acid ili ndi zinthu zambiri zopindulitsa, monga yisiti.
Mwa kapangidwe kake, mankhwalawa ndi antioxidant - mankhwala apadera omwe amatha kusokoneza zotsatira za kusintha kwaulere. Zimakuthandizani kuti muchepetse kuchuluka kwa oxidative kupanikizika, komwe ndi kowopsa kwa thupi. Lipoic acid imatha kuchepetsa ukalamba.
Nthawi zambiri, madokotala amapereka mankhwala a shuga a mtundu wachiwiri. Ndiwothandiza kwambiri mu mtundu woyamba wa matenda. Anthu odwala matenda ashuga polyneuropathy amayankha bwino pa zamankhwala, zomwe madandaulo akuluakulu a wodwala ndi awa:
- dzanzi la miyendo
- zopweteketsa mtima
- kupweteka m'miyendo ndi kumapazi,
- kumverera kutentha m'misempha.
Phindu labwino kwambiri kwa odwala matenda ashuga ndi njira yake ya hypoglycemic. Chimodzi mwazinthu zofunika kwambiri za lipoic acid ndikuti zimatha kuchita zomwe antioxidants ena - mavitamini C, E. Izi zimathanso kukhudza matenda a chiwindi, atherosclerosis, ndi matenda amkati.
Popita nthawi, thupi la munthu limapanga asidi wocheperako. Chifukwa chake, pakufunika kugwiritsa ntchito zakudya zowonjezera. Komabe, kotero kuti palibe kukaikira za kugwiritsa ntchito mitundu yambiri yazakudya, mankhwala a lipoic acid amatha kugwiritsidwa ntchito mosiyana, popeza amapezeka piritsi.
Werengani komanso Stem Cell Diabetes Therapy
Mlingo wotetezeka ndi 600 mg patsiku, ndipo maphunzirowa sayenera kupitirira miyezi itatu.
Zakudya zowonjezera thanzi zitha kukhala ndi zovuta zambiri, zomwe zimaphatikizapo zizindikiro za dyspeptic, thupi lawo siligwirizana. Ndipo asidi amene amapezeka muzakudya ndi wopanda vuto kwa anthu onse. Chifukwa cha kapangidwe kake, kuchuluka kwa chemotherapy kwa odwala khansa nthawi zina kumatha kuchepa.
Mpaka pano, palibe deta pazomwe zimachitika chifukwa chogwiritsa ntchito mankhwalawa kwa nthawi yayitali. Koma, akatswiri amati pa nthawi yoyembekezera komanso mkaka wa m'mawere ndi bwino kukana kumwa.
Kumwa mankhwala
Mu shuga mellitus, alphalipoic acid akhoza kutchulidwa ngati prophylactic mu piritsi. Ndizothekanso kukoka mtsempha, koma uyenera kusungunuka kaye ndi mchere. Nthawi zambiri, muyezo wa mankhwalawa ndi 600 mg patsiku kuti agwiritsidwe ntchito kunja, komanso 1200 mg wa mankhwala othandizira odwala, makamaka ngati wodwalayo akhudzidwa kwambiri ndi mawonekedwe a matenda ashuga a polyneuropathy.
Osavomerezeka pambuyo chakudya. Ndikwabwino kumwa mapiritsi pamimba yopanda kanthu. Ndikofunika kulingalira kuti zochitika zapamwamba za bongo sizimamveka bwino, pomwe mankhwalawa ali ndi zovuta zochepa zoyipa ndi zotsutsana.