Momwe mungagwiritsire ntchito mankhwala gabagamm?

Mankhwala othandizira antiepileptic.
Kukonzekera: GABAGAMMA®
The yogwira mankhwala: gabapentin
ATX Encoding: N03AX12
KFG: Anticonvulsant
Nambala yolembetsa: LSR-002222/07
Tsiku lolembetsa: 12/17/07
Mwini reg. acc.: WORWAG PHARMA GmbH & Co KG

Kutulutsa mawonekedwe Gabagamm, ma CD ndikuphatikizira ndi mankhwala.

Makapisozi a gelatin olimba, No. 3, yoyera, zomwe zili m'mapilogalamu - oyera.

1 zisoti.
gabapentin
100 mg

Omwe amathandizira: lactose, wowuma chimanga, talc, gelatin, titanium dioxide, iron oxide chikasu, iron oxide ofiira.

Ma PC 10 - matuza (2) - mapaketi a makatoni.
Ma PC 10 - matuza (5) - mapaketi a makatoni.
Ma PC 10 - matuza (10) - mapaketi a makatoni.

Makapisozi olimba a gelatin, No. 1, wachikasu, zomwe zili m'mapilogalamuwa ndizopera zoyera.

1 zisoti.
gabapentin
300 mg

Omwe amathandizira: lactose, wowuma chimanga, talc, gelatin, titanium dioxide, iron oxide chikasu, iron oxide ofiira.

Ma PC 10 - matuza (2) - mapaketi a makatoni.
Ma PC 10 - matuza (5) - mapaketi a makatoni.
Ma PC 10 - matuza (10) - mapaketi a makatoni.

Makapisozi a gelatin olimba, No. 0, lalanje, zomwe zimapezeka m'mabotolo ndi ufa oyera.

1 zisoti.
gabapentin
400 mg

Omwe amathandizira: lactose, wowonda wa chimanga, talc, gelatin, oxide wa titanium, iron oxide chikasu, iron oxide ofiira.

Ma PC 10 - matuza (2) - mapaketi a makatoni.
Ma PC 10 - matuza (5) - mapaketi a makatoni.
Ma PC 10 - matuza (10) - mapaketi a makatoni.

Kufotokozera kwa ZOTHANDIZA ZABWINO.
Zonse zomwe zaperekedwa zimangoperekedwa kuti mudziwe bwino za mankhwalawo, muyenera kufunsa dokotala zokhudzana ndikugwiritsa ntchito.

Pharmacological zochita za gabagamm

Mankhwala othandizira antiepileptic. Kapangidwe kazomwe amapangira mankhwala ndi ofanana ndi GABA, yomwe imakhala ngati mkhalapakati wodziwika pakatikati wamanjenje. Makina a zochita za gabapentin amakhulupirira kuti ndi osiyana ndi anticonvulsants ena omwe amagwiritsa ntchito ma GABA synapses (kuphatikizapo valproate, barbiturates, benzodiazepines, GABA transaminase inhibitors, GABA uptake inhibitors, GABA agonists ndi GABA mankhwala osokoneza bongo. Kafukufuku wa in vitro awonetsa kuti gabapentin amadziwika ndi kukhalapo kwa malo atsopano omangika a peptide mu minyewa yamatumbo amtundu, kuphatikizapo hippocampus ndi ubongo wa cortex, womwe ungakhale wokhudzana ndi ntchito ya anticonvulsant ya gabapentin ndi zotumphukira zake. Makulidwe ochulukirapo a gabapentin samamangiriridwa ku mankhwala ena wamba ndi ma neurotransmitter receptors muubongo, kuphatikiza ndi GABAA-, GABAB-, benzodiazepine receptors, glutamate receptors, glycine kapena N-methyl-D-aspartate (NMDA) receptors.

Pomaliza, magwiridwe antchito a gabapentin sanakhazikitsidwe.

Pharmacokinetics wa mankhwala.

Gabapentin amatengedwa kuchokera m'mimba. Pambuyo kumeza Cmax gabapentin mu plasma imatheka pambuyo maola 2-3. Mtheradi bioavailability pafupifupi 60%. Kulandila nthawi yomweyo monga chakudya (kuphatikiza omwe ali ndi mafuta ochulukirapo) sikukhudza ma pharmacokinetics a gabapentin.

Gabapentin samanga mapuloteni a plasma ndipo ali ndi Vd ya 57.7 L. Odwala omwe ali ndi khunyu, kuchuluka kwa gabapentin m'madzi amchere ndi 20% ya plasma yolingana ndi plasma kumapeto kwa nthawi ya dosing.

Gabapentin amangochotseredwa ndi impso zokha. Palibe zizindikiro za biotransformation la gabapentin mu thupi la munthu. Gabapentin samalimbikitsa oxidases omwe amapezeka mu metabolism ya mankhwala. Kuchotsa kufotokozedwa bwino pogwiritsa ntchito mtundu wa mzere. T1 / 2 imakhala yodziyimira payekha pakapita maola atatu.

Kuvomerezeka kwa Gabapentin kumachepetsedwa mwa okalamba komanso odwala omwe ali ndi vuto laimpso. Mlingo wa kuwongolera mosalekeza, plasma ndi chilolezo cha impso cha gabapentin ndizofanana molunjika kupangira chilolezo chain.

Gabapentin amachotsedwa ku plasma ndi hemodialysis.

Kuzungulira kwa plasma gabapentin mwa ana kunali kofanana ndi akulu.

Zisonyezero zogwiritsidwa ntchito:

Chithandizo cha kupweteka kwa neuropathic kwa anthu azaka zopitilira 18, monotherapy ya kukomoka pang'ono komanso popanda kuyamwa kwachiwiri kwa akuluakulu ndi ana azaka zopitilira 12, monga chida china chowonjezera pakukhudza pang'ono komanso popanda kuchita kwachiwiri kwa akuluakulu ndi ana azaka zitatu ndi achikulire.

Zotsatira zoyipa za Gabagamm:

Pa mbali ya dongosolo chapakati mantha ndi zotumphukira mantha dongosolo: amnesia, ataxia, chisokonezo, incoordination, maganizo, chizungulire, dysarthria, kuchulukitsidwa irritability mantha, nystagmus, kugona, maganizo nthenda, kugwedeza, khunyu, amblyopia, diplopia, hyperkinesia, cholimbikitsa, zofooketsa kapena kusowa kwa chidwi, paresthesia, kuda nkhawa, kudana, kusokonekera.

Kuchokera pamimba yodutsamo: kusintha kwa madontho a mano, kutsekula m'mimba, kudya kwambiri, mkamwa owuma, nseru, kusanza, kupweteka kwa m'mimba, kupweteka kwam'mimba, kapamba, kusintha kwa mayesero a chiwindi.

Kuchokera ku hemopoietic dongosolo: leukopenia, kuchepa kwa maselo oyera a magazi, thrombocytopenic purpura.

Kuchokera kupuma dongosolo: rhinitis, pharyngitis, chifuwa, chibayo.

Kuchokera ku minculoskeletal system: myalgia, arthralgia, mafupa a mafupa.

Kuchokera pamtima dongosolo: ochepa matenda oopsa, mawonetseredwe a vasodilation.

Kuchokera kwamikodzo dongosolo: kwamikodzo thirakiti matenda, kwamikodzo incinuence.

Zotsatira zoyipa: erythema multiforme, matenda a Stevens-Johnson.

Dermatological zimachitika: kukula kwa khungu, ziphuphu, kuyabwa, zotupa.

Zina: kupweteka kumbuyo, kutopa, kufalikira kwa edema, kusabala, asthenia, malaise, kutupa kwa nkhope, kunenepa kwambiri, kuvulala mwangozi, asthenia, matenda ofanana ndi chimfine, kusinthasintha kwa shuga m'magazi, mwa ana - kachilombo ka virus, otitis media.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere.

Maphunziro okwanira komanso osamalitsa pa chitetezo cha gabapentin pa nthawi yoyembekezera komanso mkaka wa m'mawere mwa anthu sanachitike. Ngati ndi kotheka, ntchito pa nthawi ya pakati ndi mkaka wa m`mawere ayenera kuwunika mosamala zabwino zomwe zingachitike pakubwera kwa mayiyo ndi kuopsa kwa mwana wosabadwayo kapena khanda.

Gabapentin amachotseredwa mkaka wa m'mawere. Mukamagwiritsa ntchito mkaka wa m`mawere, mawonekedwe a gabapentin wakhanda samakhazikitsidwa.

Malangizo apadera ogwiritsira ntchito Gabagamm.

Kutha kwadzidzidzi kwa mankhwala oletsa kuperewera kwa odwala omwe ali ndi gawo logwidwa kumatha kuyambitsa vuto. Ngati ndi kotheka, sinthani mlingo, lekani gabapentin kapena m'malo mwake ndi wina wothandizirayo azikhala pang'onopang'ono kwa sabata limodzi.

Gabapentin si chithandizo chokwanira cha kukomoka kopweteka.

Kuphatikizidwa ndi ma anticonvulsants, zotsatira zoyesa zamkodzo wa mkodzo wabodza zanenedwa. Kuti mudziwe mapuloteni mumkodzo, tikulimbikitsidwa kugwiritsa ntchito njira yodziwika yolimbitsa mpweya wa sulfosalicylic acid.

Odwala omwe ali ndi vuto laimpso, komanso odwala omwe ali ndi hemodialysis, ayenera kusintha njira.

Odwala okalamba angafunikire kusintha kwa mankhwalawa a gabapentin chifukwa chakuti m'gulu ili la odwala kuchepa kwa impso ndikotheka.

Kuchita bwino komanso chitetezo cha mankhwala a ululu wa neuropathic mwa odwala omwe ali ndi zaka zosakwana 18 sizinakhazikitsidwe.

Mphamvu ndi chitetezo cha gabapentin monotherapy pochotsa kugwidwa kwakanthawi kwa ana osaposa zaka 12 ndi zina zowonjezera ndi gabapentin pochotsa kugwidwa pang'ono kwa ana osaposa zaka 3 sizinakhazikitsidwe.

Munthawi ya chithandizo musalole kumwa mowa.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Asanadziwe momwe munthu angachitire chithandizo, wodwala ayenera kupewa zoopsa zomwe zimakhudzana ndi kufunika koika mtima komanso kuwonjezereka kwa ma psychomotor.

Kutulutsa mafomu ndi kapangidwe kake

Mankhwalawa amapangidwa mwa mawonekedwe a makapisozi, wokutira ndi chipolopolo cholimba cha gelatin, pakukonzekera pakamwa.

Zida zamankhwala zimakhala ndi 100, 300 kapena 400 mg yogwira ntchito ya gabapentin. Monga zida zina zopangira chipolopolo chakunja zimagwiritsidwa ntchito:

• talcum ufa
• shuga mkaka
• wowuma chimanga
• titanium dioxide.

Kutengera Mlingo, makapisozi amasiyanitsidwa ndi mitundu: pamaso pa 100 mg ya gabapentin, kuphatikiza kwa gelatin kumakhalabe koyera, pa 200 mg ndi chikasu chifukwa cha utoto wozikidwa ndi iron oxide, ndipo 300 mg ndi lalanje. Mkati mwa makapisozi mumapezeka ufa oyera.

Mankhwalawa amapangidwa mwa mawonekedwe a makapisozi, wokutira ndi chipolopolo cholimba cha gelatin, pakukonzekera pakamwa.

Contraindication

Mankhwalawa sanatchulidwe ngati pali chiwopsezo cha minyewa ya wodwalayo kupita ku zinthu zina za Gabagamm. Chifukwa cha kupezeka kwa kuphatikizika kwa lactose, mankhwalawa amadziwitsidwa kuti agwiritsidwe ntchito kwa odwala omwe ali ndi cholowa cha mkaka wa shuga ndi galactose, chifukwa cha kuperewera kwa lactase ndi malabsorption a monosaccharides.

Momwe mungatenge Gabagamm

Mankhwala amatengedwa pakamwa, mosasamala kanthu za kudya. Ngati mukufuna kusiya mankhwala, muyenera kusiya kugwiritsa ntchito Gabagamm pang'onopang'ono sabata limodzi. Mankhwala osokoneza bongo omwe ali ndi kuchuluka kwa mankhwalawa amachitika ngati wodwalayo watopa, kuchepa thupi kapena kuchepa kwambiri kwa wodwalayo, kuphatikizapo kufooka panthawi yobwezeretsa pambuyo poti muwonjezere. Muzochitika zotere, ndikofunikira kuyamba ndi mlingo wa 100 mg.

Njira yochizira imakhazikitsidwa ndi adotolo kutengera mtundu wa wodwalayo komanso chithunzi cha chipatala.

Ndi matenda ashuga

Mankhwalawa sakukhudzanso shuga wa plasma ndipo sasintha mahandidwe obisika a insulin ndi ma cell a beta a kapamba, chifukwa chake palibe chifukwa chofuna kupatuka pamankhwala omwe amalimbikitsidwa a matenda a shuga.

Zowawa za Neuropathic A. B. Danilov. Kupweteka kwamitsempha. Kuzindikira ndi kuchiza matenda opweteka

Matumbo

Zotsatira zoyipa zamagetsi zimadziwika ndi zochitika zotsatirazi:

• kupweteka kwa epigastric
• kukomoka
• kusanza, kutsegula m'mimba, kusanza,
• kutupa kwa chiwindi
• kuchuluka kwa hepatocytic aminotransferases,
• jaundice kumbuyo kwa hyperbilirubinemia,
• kapamba
• dyspepsia ndi pakamwa lowuma.

Monga mbali yakugwa kwa m'mimba, matenda a anorexia angachitike.
Flatulence ndi chizindikiro cha zotsatira zoyipa za mankhwalawa.
Pancreatitis imatha kuwonekanso ngati mavuto.

Pakati mantha dongosolo

Ndi zoletsa zamanjenje, ndizotheka:

• chizungulire
• kuphwanya kwamtundu wa mayendedwe,
• choreoathetosis,
• kutayika kwa malingaliro
• kuyerekezera
• Kutayika kwa kuwongolera m'maganizo,
• kuchepa kwa chizindikiritso, malingaliro operewera,
• paresthesia.

Nthawi zina, amnesia amakula, kufalikira kwa khunyu kumawonjezeka.

Njira za Chithandizo cha Khunyu

Palibe njira ina yothandizira chithandizo cha mankhwala a khunyu. Kuzindikira matenda aubongo kumachitika pogwiritsa ntchito zida zamakono zamankhwala. Nthawi zambiri, chithandizo chamankhwala chimaphatikizapo kumwa mankhwala omwe amalimbikitsa ntchito ya chotupa cham'mimba, amachepetsa mphamvu ya mapangidwe amitsempha yamagazi.

Masiku ano, mankhwalawa akhunyu osiyanasiyana, chifukwa khunyu imatha kudziwonetsa mosiyanasiyana (kamodzi pachaka kapena kangapo patsiku), antiepileptic, anticonvulsant mankhwala amagwira ntchito. Chizindikiro chachikulu cha kuyamba kwa kukomoka ndikuchita kupweteka kwa minofu, kusokonezeka kwa dongosolo logaya chakudya ndi kukodza, kusiya kukumbukira, kuzindikira zenizeni, kuiwalika kukumbukira, kulawa, kumva, masomphenya.

Mankhwala amathandiza kupewa kukomoka isanakwane. Nthawi zambiri, madokotala amalankhula za mankhwalawa "Gabagamm." Malangizo ogwiritsira ntchito, ma analogues, ndemanga za akatswiri ndi abale a anthu omwe ali ndi khunyu za mankhwala adzakambidwa pansipa.

Mankhwala "Gabagamma": mawonekedwe a kumasulidwa, kapangidwe

Chifukwa chake, tiyeni tiwone zonse zomwe zikuphatikizapo malangizo azachipatala kuti azigwiritsa ntchito. "Gabagamma" ndi kapisozi kolimba ka gelatin koyera, kaso kapena lalanje. Ndikofunikira kudziwa kuti mtundu wa izi umawonetsa kuchuluka kwa chinthu chomwe chikugwira ntchito.

Chifukwa chake, m'matumba oyera, gabapentin 100 mg, chikasu 300 mg, lalanje 400 mg. Chifukwa chake, m'malo onsewo, kuphatikizira kwa mankhwala kumayikidwa.

Mankhwala "Gabagamma" amapezekanso m'mapiritsi okhala ndi filimu. Kugwiritsa ntchito bwino kwa mankhwalawa mu ubongo sikudalira mtundu wa mankhwala.

Mitundu ya mankhwala a Gabagamm imapangidwa ku Germany ndi kampani yopanga mankhwala Woezag Pharma GmbH & Co KG. Mankhwala achijeremani ndi abwino kwambiri. Chifukwa chake, pafupifupi zabwino zokhazokha zomwe zimapezeka pazokhudza makapisozi ndi mapiritsi a "Gabagamm".

Mankhwala osokoneza bongo

Kuti mumvetsetse momwe mankhwala othandizira amagwiritsidwira ntchito, muyenera kuphunzira mosamala malangizo onse omwe ali ndi malangizo ogwiritsira ntchito. "Gabagma", monga tafotokozera pamwambapa, ndimankhwala osokoneza bongo. Mphamvu yake yogwira ntchito imafanana ndi a GABA blockers - gamma-aminobutyric acid ogwiritsidwa ntchito pochiza matenda aubongo. Komabe, kagwiritsidwe kake ka mankhwalawa ndizosiyana pamlingo wa thupi. Gabapentin sisonkhanitsa kapena kuchotsa GABA m'thupi. Amamangirira gawo la α2-δ gawo la mayendedwe a calcium odalira mphamvu yamagetsi, chifukwa chomwe kuchepa kwa kayendedwe ka calcium ions, kamene kamakhudzidwa ndi zochitika zathupi zomwe zimayambitsa kupweteka kwa neuropathic. Poyerekeza ndi chithunzi chithunzichi, kapangidwe ka GABA kakulirakulira, kumasulidwa kwa ma neurotransmitters a gulu la monoamine kumapanikizika.

Pazambiri kuchuluka kwa gabapentin m'mwazi zimatheka patatha maola awiri kapena atatu pambuyo pa kuperekedwa. Kudya sizikhudzana ndi mayamwa.

Malinga ndi malangizo ogwiritsira ntchito, "Gabagamma" imachotsedwa m'thupi pambuyo pa maola asanu mpaka asanu ndi awiri, mosasamala kanthu za kuchuluka kwa impso, ndi impso zosasinthika.

Kwa anthu omwe ali ndi matenda a chiwindi ndi impso, mankhwalawa amachotsedwa ndi hemodialysis.

Mlingo woyenera

Malangizo okonzekera Gabagamm kuti agwiritse ntchito amayang'ana kwambiri kuti atha kutengedwa nthawi yomweyo ndi mankhwala ena antiepileptic, ndipo samakhudza kugwira ntchito kwa njira zakulera zapakamlomo, makamaka zomwe zimakhala ndi norethindrone kapena ethinyl estradiol. Komanso sizowopsa kumwa mankhwalawa omwe amalepheretsa impso za gabapentin ndi impso.

Mankhwala a gulu la antacid amachepetsa kwambiri kukhudzana kwa gabapentin, kotero amawotenga patatha maola awiri atatha kutsata.

Mankhwala "Gabagamma" amalimbikitsa kutenga malangizo kuti agwiritsidwe ntchito molingana ndi mlingo wina, womwe ungasinthidwe ndi adokotala wokha. Kudya kwa mapiritsi ndi makapisozi sikumamangidwa pakudya, chinthu chachikulu ndikutsata kwawo ndikumamatira pakati pa Mlingo wa nthawi yodziwikiratu kuti mupewe kuchuluka kwa mankhwalawa.

Pansipa afotokozeredwa momwe mungamwe mankhwalawa "Gabagamma", zomwe zikugwiritsidwa ntchito zikulimbikitsidwa kuti zisasinthe.

Ndi ululu wa neuropathic, achikulire amakhazikitsidwa ndi 900 mg ya gabapentin patsiku. Mlingowu umagawika katatu ndipo umatengedwa pafupipafupi, osapitilira maola 12. Ngati ndi kotheka, mlingo umatha kuwonjezeka mpaka 3600 mg wa patsiku.

Ndi kukomera pang'ono komwe kumawonetsedwa kwa akulu ndi ana opitirira zaka khumi ndi ziwiri, mlingo womwewo umayikidwa - kuchokera 900 mg mpaka 3600 mg, wogawidwa m'malo atatu tsiku lililonse.

Pakulephera kwa impso, mlingo umachepetsedwa malinga ndi mtengo wa QC (ml / min). Akafika:

- oposa 80, ndiye kuti mlingo wa gabapentin ndi 900-3600 mg,

- 50-79, ndiye kuti 600-1800 mg amatengedwa,

- 30-49, Mlingo wa 300-900 mg,

- 15-29, yalimbikitsa 150-600 mg,

- osakwana 15, motero, 150-300 mg wa gabapentin.

Mlingo wa Gabagamm wa 300 mg umaperekedwa kwa odwala a hemodialysis. Malangizo ogwiritsidwira ntchito amalimbikitsa kuti wodwala atenge 200 mg ya gabapentin pambuyo pa njira iliyonse ya maola anayi oyeretsa. Kutenga mankhwalawo kumayendetsedwa ndi kuyang'aniridwa ndi dokotala.

Malangizo a "Gabagamma" a mankhwalawa amalimbikitsa kuti odwala omwe akudwala kwambiri komanso odwala omwe ali ndi vuto lochepa thupi azitha kulandira 100 mg pambuyo pochita opaleshoni yovuta kwambiri.

Zochita Zoyipa Zomwe Zimayambitsa Mankhwala

Zotsatira zoyipa za mankhwala "Gabagamm" zimatsimikiziridwa ndi malangizo omwe angagwiritsidwe ntchito. Mapiritsi a Gabapentin sakhala otetezeka. Amatha kuyambitsa kupatuka kwakukulu mu thanzi.

Nawo mndandanda wawo, womwe umawonetsedwa ndi malangizo ogwiritsira ntchito mankhwalawa "Gabagamma", ndemanga za odwala ambiri ndi abale awo:

- mawonetseredwe a zizindikiro za matenda, tizilombo toyambitsa matenda, chibayo, kutupa kwa ma genitourinary system, otitis media,

- zotupa zoyipa ndi kuyabwa,

- kuchuluka kudya kapena kuchepa kwake, zomwe zimayambitsa matenda a anorexia,

- kusokonezeka kwa mitsempha, kukwiya, kuyerekezera zinthu, kusokonezeka kwa malingaliro, kusowa kwa kuganiza, kusokonezeka kwa malingaliro,

- kunjenjemera, kufooka, kugona, kupweteka pamutu, kukomoka, kusowa kwa Reflex sign, kuiwala kukumbukira,

- Kuchepa kwa masomphenya.

- kukomoka kwa mtima, kupanikizika kwakukulu,

- rhinitis, bronchitis, pharyngitis,

- nseru, kupweteka m'mimba ndi m'mimba, kutsegula m'mimba, jaundice,

- kutupa kwa thupi, ziphuphu zakumaso thupi lonse,

- kuphatikizika ndi kupweteka kwa minofu thupi lonse.

- kusabala kwa amuna, gynecomastia,

- kudumpha m'magazi a odwala matenda ashuga,

- nkhanza za ana ndi ma hyperkinesis.

Monga mukuwonera, mankhwalawa "Gabagamma" si mtundu wamankhwala omwe angatengedwe popanda mankhwala a dokotala. Zovuta zolimbitsa thupi kwambiri zitha kupezeka ngati mukulingalira nokha.

Mankhwala othandizira antiepileptic: zili bwino?

Masiku ano, makampani opanga mankhwala amapanga mankhwala angapo antiepileptic. Zitha kukhala ndi gabapentin kapena zinthu zina zomwe zimagwira bwino mu ubongo.

Pakati pawo, ndizosatheka kusiyanitsa zabwino kapena zoipa. Mlandu uliwonse wa khunyu ndi munthu payekha, ndipo madokotala onse amaletsa izi, kupereka mankhwala kuti athandize wodwala.

Mankhwala otsatirawa ndi fanizo la mankhwala a "Gabagamma": makapisozi "Neurotin" (Germany), "Gapentek" (Russia), "Tebantin" (Hungary), "Topiomat" (Russia), "Katena" (Croatia).

Zizindikiro za pharmacological ndizofanana ndi makapisozi a Algerika ndi Lyric, omwe amaphatikiza pregabalin, mapiritsi a Wimpat okhala ndi lacosamide, mapiritsi a Levitsit okhala ndi levetiracetam, ndi mapiritsi a Paflugeral.

Mankhwala "Gabagamm": malingaliro a madokotala

Kuchokera pamndandanda waukulu wa mankhwala othandizira antiepileptic, madokotala nthawi zambiri amapereka mankhwala a Gabagamm kwa odwala awo. Chifukwa chiyani, ngati pamashelefu apachipatala mungapeze mankhwala ambiri otsika mtengo kuti muthane nawo?

Chowonadi ndi chakuti ndimapiritsi a "Gabagamma" omwe amawunikira madokotala amakhala apamwamba komanso othandiza kwambiri. Ngakhale mndandanda waukulu wazovuta zoyipa za thupi la wodwalayo kuti uchiritsidwe ndi mankhwalawa, chisonyezo chochititsa chidwi cha anthu omwe abwerera m'moyo wonse sasiya kugwiritsa ntchito.

Popeza chizolowezi chowongolera mayadi awo ndikofunikira kwa dotolo, kuyang'ana kwambiri pamankhwala opangidwa ndi Germany, ngakhale ndi okwera mtengo. Madokotala amalimbikitsa kugwiritsa ntchito ana.

Mwachilengedwe, zoyipa za mankhwalawa sizingachitike mwa zonse. Koma madokotala ambiri amazindikira kugona tulo kwa odwala awo, kukhumudwa, kupweteka kwa mutu. Nthawi zambiri, zizindikirozi zimatha pambuyo pochita mankhwalawa ndi gabapentin.

Chidwi chachikulu chimaperekedwa kwa madokotala pochiza ana. Popereka mankhwala, madokotala nthawi zonse amasanthula chithunzi cha thanzi la mwana kuti asaonjezere zovuta zake kapena kukhala pafupi ndi zovuta.

Ndemanga za Mankhwala

Pali odwala ambiri omwe ali ndi matenda a khunyu omwe adakumana ndi mapiritsi a Gabagamm pa thanzi lawo. Ndemanga za anthu zimafotokoza za kusapeza bwino komanso phindu la mankhwalawo.

Achibale omwe akusamalira odwala amalephera kuzindikira, ambiri amadandaula za kupweteka mutu, nseru, kugwedezeka ndi chizungulire. Komabe, molingana ndi maziko a zovuta izi, kupita patsogolo kumawonedwa poyerekeza ndi kuchepa kwa pafupipafupi kwa kugwidwa khunyu.

Amawonetsedwa malo osokoneza bongo komanso mkwiyo wambiri ukamatha mlingo wa mankhwalawo umachepa. Mankhwalawa amakhala ndi mphamvu pang'onopang'ono, zomwe zimakhudza thupi, ndiye kuti simukuyenera kuyembekezera kuti zotsatira zabwino zimatenga mphamvu yoyamba. Kuti musinthe zinthu zabwino muyenera kupita kukalandira chithandizo. Zotsatira zakugwiritsa ntchito mankhwalawa "Gabagamma" ndizokhutitsidwa ndi masauzande odwala. Makolo a ana omwe ali ndi matenda a khunyu amayamika kwambiri kampani yopanga mankhwala ku Germany chifukwa cha mankhwala abwino. Kupatula apo, aliyense ayenera kukhala ndi mwayi wokhala ndi thanzi labwino, makamaka m'badwo wachinyamata.

Nkhaniyi idafufuza za mankhwala a antiepileptic, anticonvulsant "Gabagamm", omwe akuwonetsa kuti mankhwalawa adapangitsa kuthana bwino ndi matenda osokoneza bongo a ubongo wa munthu. Kuchita bwino kwa mankhwalawa kumatsimikiziridwa ndi ziwerengero zochititsa chidwi za milandu yochira, pomwe zaka makumi awiri zapitazo khunyu lidanenedwa ngati matenda osachiritsika.

Masiku ano, chifukwa cha kuyesayesa kwa mabungwe azachipatala, zitha kutsimikizira kuti khunyu ikhoza kuwongoleredwa moyenera, chiwonetsero chawo chitha kupewedwa ngati mankhwala ogwira mtima atengedwa.

Izi sizothandiza. Mankhwala achijeremani amatha kugulidwa popanda zovuta ku pharmacy yanyumba iliyonse ndipo osakana kwa abale anu ndi anzanu pamankhwala abwino omwe amalimbikitsa kuti zotsatira zake zitheke.

Ponena za ma fanizo ake, ndiye kuti pakati pawo palinso mankhwala ambiri oyenera. Kodi ndi mankhwala ati omwe amafunsidwa kwa wodwala, sasankhidwa ndi wodwalayo kapena abale, koma ndi dokotala wopita. Makamaka zikafika pamatenda azeru monga khunyu.

Nthawi zambiri, chomwe chiri choyenera chimatsimikiziridwa ndi njira yoyeserera mosalekeza komanso kafukufuku wazotheka kuti achire. Mankhwala "Gabagamma" ndi mtsogoleri wazabwino, koma izi sizitanthauza kuti khunyu sikhala yothandiza kwa ena.

Masiku ano, kwakhala kotheka kuchiza "matenda achilendo" chifukwa chamankhwala ambiri ogwira mtima omwe amapangidwa ndi makampani onse azachipatala ndi achilendo.

Mankhwala

Mankhwala anticonvulsant a m'badwo wachiwiri ndi analogue ya GABA, yomwe, ngakhale akufanana, sikuti amagonist a GABA receptors ndipo samakhudza kagayidwe ka GABA.

Sichimanga kwa benzodiazepine receptors ndi glutamate ndi glycine receptors. Gabapentin amamangirira ku α2-σ kugawa kwa njira za calcium, zomwe zimapangitsa kutsika kwa magazi a calcium ions, omwe amathandizira kukulitsa kupweteka kwa neuropathic. Njira ina yothetsera ululu ndi kuwonjezeka kwa kapangidwe ka GABA.

Simalumikizana ndi mayendedwe a sodium, monga carbamazepine ndi phenytoin. Mankhwalawo poyambirira ankapangira mankhwala khunyupambuyo pake adagwiritsidwa ntchito ngati chithandizo kupweteka kwa m'mimba. Imalekereredwa bwino ndi odwala.

Zotsatira zoyipa

• mutu kukokanakutengeka mtima amnesiachisokonezo kuyerekezerakugona kapena kugona. kukhumudwankhawa
• kuwonongeka kwamawonekedwe diplopia, otitis mediatinnitus
• minofu dystoniakuphwanya Reflex nystagmus,
• kuthamanga kwa magazi, palpitations,
• chisangalalo, nseru, kupweteka m'mimba, kapamba, kukomoka, kutsegula m'mimba kapena kudzimbidwakukamwa kowuma, kusanza, kuchuluka kwa "chiwindi" transaminases, jaundice, chiwindi,
• leukopeniakuvulaza thrombocytopenia,
• arthralgiakupweteka kumbuyo myalgia,
• kutsokomola kupuma movutikira, pharyngitis, bronchitis, chibayo,
• ziphuphuzotupa pakhungu ndi kuyabwa, kukokoloka kwachisangalalo,
• kwamikodzo kusagonja kusabala.

Kutulutsa mawonekedwe ndi kapangidwe kake

Mlingo wa Gabagamm - makapisozi olimba a gelatin:

• 100 mg: kukula No. 3, oyera,
• 300 mg: kukula No. 1, chikasu
• 400 mg: kukula 0, lalanje.

Zolemba za Capsule: ufa oyera.

Kudzaza kwa kapisozi: 10 ma PC. mu chithuza, pamatafulidwe okhala ndi matuza 2, 5 kapena 10.

Zogwira pophika: gabapentin, mu kapisozi 1 - 100, 300 kapena 400 mg.

Zowonjezera: titanium dioksidi, talc, wowuma chimanga, gelatin, lactose, utoto wa iron utayidi wofiira ndi wachikasu.

Kuchokera ku genitourinary system

Nthawi zina, odwala omwe amatha kugwira matendawa amatha kudwala matenda amkodzo, amachepetsa ma erections, enuresis (kukodza kwamikodzo), komanso kulephera kwa impso.

Nthawi zina, odwala omwe amatha kugwira matendawa amatha kudwala matenda amkodzo thirakiti.

Zokhudza mphamvu pakuwongolera njira

Poganizira kuopsa kwa mayankho osavomerezeka mu chapakati mantha dongosolo (CNS) munthawi yamankhwala othandizira, tikulimbikitsidwa kuti muchepetse kugwira ntchito ndi zida zowopsa kapena zovuta, kuyendetsa galimoto komanso kuchita zinthu zomwe zimafunikira chidwi komanso kuthamanga kwa mayendedwe ake kuchokera kwa wodwalayo.

Malangizo apadera

Ngakhale kuti palibe achire achire ndi gabapentin mankhwala, pali chiopsezo cha kubwereranso minofu kukokana kwa odwala omwe ali ndi gawo lochita kupweteka. Ndikofunika kukumbukira kuti mankhwalawa si chida chothandiza polimbana ndi khunyu.

Ndi chithandizo chophatikizidwa ndi Morphine, amafunika kuwonjezera kuchuluka kwa Gabagamm atatha kufunsa dokotala. Pankhaniyi, wodwalayo ayenera kuyang'aniridwa mosamalitsa kuchipatala kuti ateteze kuyambika kwa zizindikiro za kukhumudwa kwa chapakati mantha dongosolo. Ndi kukula kwa zizindikiro za matenda amanjenje, ndikofunikira kuchepetsa mlingo wa mankhwalawa.

Ndi chithandizo chophatikizidwa ndi Morphine, amafunika kuwonjezera kuchuluka kwa Gabagamm atatha kufunsa dokotala.

M'maphunziro a labotale, zotsatira zoyipa zabodza la kukhalapo kwa proteinuria zitha kulembedwa, chifukwa chake, poika Gabagamma palimodzi ndi anticonvulsants ena, ndikofunikira kufunsa ogwira ntchito labotale kuti achite kafukufuku mwanjira yeniyeni kuti akonzekere sulfosalicylic acid.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Zotsatira zamankhwala pazotsatira za mankhwalawa pakukonzekera kwa embryonic sizinachitike. Chifukwa chake, gabapentin imalembedwa kwa amayi apakati pokhapokha ngati pali zovuta zambiri, pomwe zotsatira zoyipa za mankhwalawo kapena zoopsa ku moyo wa mayi zimaposa chiopsezo cha kugwiriridwa kwa fetal.

Gabapentin amawonetsedwa kwa amayi apakati omwe ali ndi vuto kwambiri.

Mankhwala othandizira amatha kupaka mkaka wa mayi, kotero kuyamwitsa kuyenera kusiyidwa pakumwa mankhwala.

The ntchito aimpso kuwonongeka

Pamaso pa kulephera kwa impso, mulingo wa mankhwalawa umasinthidwa malinga ndi chilolezo cha creatinine (Cl).

Gabagamma, malangizo ogwiritsira ntchito (Njira ndi Mlingo)

Mankhwala amatengedwa pakamwa.

Ndi ululu wa neuropathic Mlingo woyambirira wa 900 mg / tsiku., wogawidwa 3 waukulu. Ngati ndi kotheka, pang'onopang'ono muwonjezeke mpaka 3600 mg / tsiku, omwe ndi mlingo waukulu tsiku lililonse. Monga lamulo, kuchepa kwa ululu kumayambira sabata la 2, komanso kuchepa kwakukulu mu sabata la 4.

Chifukwa cha kukokana Mankhwalawa amayambanso ndi 300 mg katatu patsiku, ndikuwonjezera mlingo wa 3600 mg / tsiku. pamaphwando atatu. Mankhwalawa mopanda mantha angagwiritsidwe ntchito limodzi ndi ma anticonvulsants ena, pomwe kuchuluka kwa gabapentin mu seramu sikuwongolera.

Odwala ofooka, pambuyo kufalikira kwa chiwalo, ndimalemera ochepa, kuchuluka kwamankhwala kumachitika pang'onopang'ono, pogwiritsa ntchito mankhwalawa 100 mg. Kuchepetsa Mlingo kapena kugwiritsa ntchito mankhwala kumachitika pang'onopang'ono sabata limodzi.

Pa chithandizo, kuyendetsa galimoto kuyenera kupewedwa.

Bongo

Ndi mankhwalawa chifukwa cha limodzi mlingo waukulu, Zizindikiro za mankhwala osokoneza bongo zimawonekera.

• chizungulire
• mawonekedwe amtundu wamtundu wokhala ndi gawo la zinthu,
• vuto la kulankhula
• ulesi,
• kugona
• kutsegula m'mimba

Chiwopsezo chowonjezeka kapena chowonjezereka cha zovuta zina. Wovutitsidwayo amayenera kugonekedwa kuchipatala kuti amuchotsere m'mimba, malinga ndi momwe makapisozi amatengedwa pakamwa maola 4 omaliza. Chizindikiro chilichonse cha bongo chimatha kudzera mwa chithandizo. Hemodialysis ndiyothandiza.

Ndi mankhwala osokoneza bongo ambiri, kugona kungachitike.

Kuchita

Ndi olowa mankhwala morphine Kuwonjezeka kwa mlingo wa gabapentin ndikofunikira. Komabe, ndikofunikira kuwunikira zizindikiro za kukhumudwa kwapakati pamanjenje, monga kugona.

Kuchita ndi phenobarbital, carbamazepine, phenytoin ndi valproic acid osawonedwa.

Ntchito ndi kulera kwamlomo sizikhudzanso pharmacokinetics ya mankhwala onse awiri. Phwando maantacid, zotayidwa ndi okhala ndi magnesium kuchepa kwa bioavailability wa gabapentin amadziwika. Kutenga kwa mankhwalawa kumafalikira nthawi.

Khalid sizikhudza kutuluka kwa gabapentin. Kutsika kwake pang'ono kumadziwika mukamatenga cimetidine.

Kupweteka kwamitsempha m'mimba mwa akulu

Mlingo woyamba wa Gabagamm ndi 900 mg.Ngati ndi kotheka, mlingo umakulitsidwa pang'onopang'ono. Mlingo wapamwamba wa tsiku ndi tsiku ndi 3600 mg.

Mutha kuyamba kulandira chithandizo mwachangu ndi mlingo wa 900 mg - 300 mg katatu patsiku, kapena mutha kutsatira njira yotsatirayi: tsiku loyamba - 300 mg kamodzi, tsiku lachiwiri - 300 mg kawiri patsiku, tsiku lachitatu - 300 mg katatu patsiku .

Kukakamira pang'ono mwa akulu ndi ana azaka 12

Pagawo lililonse ogwira Gabagamm tsiku lililonse amatha kusiyanitsa pakati pa 900-3600 mg.

Kumayambiriro kwa mankhwalawa, mutha kukupatsani mlingo wa 900 mg - 300 mg katatu patsiku, kapena muonjezere pang'onopang'ono mlingo malinga ndi chiwembu chomwe tafotokozachi. Kupitilira apo, ngati kuli kotheka, pitilizani kuonjezera mlingo. Mlingo wovomerezeka waukulu ndi 3600 mg mu 3 mgawani.

Pofuna kupewa kukomoka mobwerezabwereza, nthawi yayitali pakati pa mulingo sayenera kupitirira maola 12.

Kuyenderana ndi mowa

Panthawi yamankhwala, mumaletsedwa kumwa mowa. Ethanol mu kapangidwe ka zakumwa zoledzeretsa zimakhala ndi mphamvu zoletsa zamkati mwa dongosolo lamanjenje ndipo zimachulukitsa zotsatira zoyipa.

The fanizo la mankhwala akuphatikiza:

Kusinthira ku mankhwala ena amaloledwa pokhapokha kukaonana ndi azachipatala ndi mphamvu zochepa za Gabagamm kapena kuwoneka ngati pali zovuta zina.

Monga analogue, mutha kugwiritsa ntchito Neurontin.

Mimba komanso kuyamwa

Ziwopsezo za khunyu komanso antiepileptic

Chiwopsezo cha kubereka kwa ana a azimayi ogwidwa ndi khunyu chikukula chifukwa cha zinthu ziwiri ndi ziwiri. Kukula kwambiri kwa milomo yofinya, kuphwanya kapangidwe ka mtima ndi chubu la neural. Multicomponent antiepileptic mankhwala atha kuphatikizidwa ndi chiwopsezo chachikulu cha zovuta zapamadzi poyerekeza ndi monotherapy. Izi zikufotokozera kufunika kogwiritsa ntchito mitundu yamagulu a monotherapy ngati nkotheka. Amayi onse oyembekezera komanso azimayi omwe ali ndi zaka zakubadwa omwe amafunikira antiepileptic chithandizo ayenera kukhala ndi upangiri wofunsa asanayambe. Pokonzekera kukhala ndi pakati, ndikofunikira kuganiziranso za kufunika kwa kupatsa mankhwala antiepileptic. Kuchotsa lakuthwa kwa antiepileptic mankhwala nkosavomerezeka, chifukwa izi zimatha kubweretsa ndikumayipa kwambiri thanzi la mayi ndi mwana. Kuchedwa kwa chitukuko cha ana kuchokera kwa amayi omwe ali ndi khunyu ndikosowa. Ndikosatheka kusiyanitsa ngati kuchedwa kuyambukira kumachitika chifukwa cha zovuta zamtundu, zinthu zina, khunyu mwa mayi, kapena kumwa mankhwala oletsa antiepileptic.

Chiwopsezo chokhudzana ndi mankhwala a gabapentin

Palibe deta yokwanira yogwiritsira ntchito gabapentin mwa amayi apakati. Kafukufuku wazinyama awonetsa kuti mankhwalawa ali ndi poizoni ku njira yobereka. Chiwopsezo chomwe chingakhalepo kwa anthu sichikudziwika.

Gabapentin sayenera kugwiritsidwa ntchito panthawi yomwe ali ndi pakati pokhapokha ngati phindu lomwe lingakhalepo kwa mayi likuwonetsa bwino lomwe kuwopsa kwa mwana wosabadwayo.

Palibe lingaliro limodzi loti ngati gabapentin amatengedwa ndi amayi pa nthawi ya khunyu amatha kuwonjezera mwayi wokhala ndi matenda obadwa nawo kwa ana.

Gabapentin amachotseredwa mkaka wa m'mawere. Popeza kuchuluka kwa mankhwalawa kwa makanda sikunaphunzire, kuyang'anira kwa gabapentin kwa amayi oyamwitsa kuyenera kuchitika mosamala. Kugwiritsa ntchito gabapentin mwa amayi oyamwitsa kumakhala koyenera pokhapokha ngati phindu la mayi limaposa chiwopsezo cha mwana.

Mlingo ndi makonzedwe

Pogwiritsa ntchito pakamwa.

Gabapentin akhoza kumwedwa ndi chakudya kapena payokha, kapukusiyu ayenera kumeza lonse ndikusambitsidwa ndi madzi okwanira (kapu yamadzi).

Poyamba kugwiritsa ntchito mankhwalawa, mosasamala kanthu za mawonekedwe, mapangidwe a mlingo, umagwiritsidwa ntchito pa Gawo 1. Dongosolo ili likulimbikitsidwa kwa akulu ndi achinyamata azaka 12 ndi akulu. Ndondomeko ya kumwa kwa ana osakwana zaka 12 imaperekedwa mosiyana.

Kuchotsa kwa Gabapentin kuyeneranso kuchitidwa pang'onopang'ono, mosasamala kanthu za mawonekedwe, kwa sabata limodzi.

Chithandizo cha khunyu nthawi zambiri chimatenga nthawi yayitali. Mulingo woyenera kwambiri umatsimikiziridwa ndi dokotala, kutengera mphamvu ndi kulolerana kwa munthu payekha.

Akuluakulu ndi achinyamata (woposa zaka 12)

Mlingo wogwira mtima wa khunyu (m'maphunziro azachipatala) amachokera ku 900 mpaka 3600 mg / tsiku. Chithandizo chimayamba ndi kupatsidwa mlingo wa mankhwalawa, monga momwe tafotokozera 2, kapena mlingo wa 300 mg katatu patsiku patsiku la 1. Kenako, kutengera kupirira kwa munthu aliyense payekha komanso kugwiranso ntchito kwake, mlingowo ukhoza kuwonjezeredwa ndi 300 mg / tsiku lililonse masiku 2 mpaka 3 mpaka kufika pa 3600 mg / tsiku. Kwa odwala ena, kuchepetsedwa pang'ono kwa gabapentin kungakhale kofunikira. Nthawi yochepa kwambiri kuti mufikire mlingo wa 1800 mg / tsiku ndi sabata 1, 2400 mg / tsiku - masabata awiri, 3600 mg - masabata atatu.

Pazoyesa zanthawi yayitali zotseguka, mlingo wa 4800 mg / tsiku umaloledwa bwino ndi odwala. Mlingo wa tsiku ndi tsiku uyenera kugawidwa m'magawo atatu. Pazikhala pakati Mlingo wa mankhwala sayenera kupitirira maola 12 kuti kupewa kusokonezeka anticonvulsant mankhwala ndi kupewa kupezeka.

Ana a zaka za ku b ndi kupitilira.

Mlingo woyambira wa mankhwalawa uyenera kukhala 10-15 mg / kg / tsiku. Mlingo wogwira ntchito uyenera kupezeka mwa kutumiza mankhwalawa mkati mwa masiku atatu. Mlingo wothandiza wa gabapentin mwa ana azaka 6 ndi akulu ndi 2 5 - 3 5 mg / kg / tsiku. Zatsimikiziridwa kuti mlingo wa 50 mg / kg / tsiku unkaperekedwa moyenera ndi odwala pazoyeserera zazitali zamankhwala. Mlingo wa tsiku ndi tsiku uyenera kugawidwa magawo ofanana (3 pakudya katatu patsiku), nthawi yayitali yolumikizira pakati pa mankhwala sayenera kupitirira maola 12.

Palibe chifukwa chowunikira kuchuluka kwa serum gabapentin. Gabapentin angagwiritsidwe ntchito limodzi ndi mankhwala ena antiepileptic osawopa kusintha kuchuluka kwa mankhwalawa mu plasma.

Kupweteka kwapakati pa neuropathic Akuluakulu

Chithandizo chimayamba ndi kuperekedwa kwa mlingo wa mankhwalawa, monga tafotokozera pa tebulo 1. Kuyamba kwa 900 mg / tsiku. Iyenera kugawidwa m'magawo atatu. Kenako, kutengera kupirira kwa munthu aliyense payekha komanso kugwiritsa ntchito bwino, mlingowo umatha kuwonjezeredwa ndi 300 mg / tsiku tsiku lililonse lililonse la 2-3 mpaka 3600 mg / tsiku. Kwa odwala ena, kuchepetsedwa pang'ono kwa gabapentin kungakhale kofunikira. Nthawi yayifupi kwambiri kuti mufikire mlingo wa 1800 mg / tsiku - sabata 1, 2400 mg / tsiku - masabata awiri, 3600 mg / tsiku - masabata atatu. Kuchita bwino ndi chitetezo cha gabapentin pochizira zowawa za neuropathic (mwachitsanzo, kupweteka kwa matenda a shuga Ngati wodwalayo akufunika chithandizo chotalikirapo (chopitilira miyezi isanu) ndi gabapentin kupweteka kwa neuropathic, dokotala amayenera kuwunika momwe wodwalayo aliri asanapite kuchipatala.

Gwiritsani ntchito m'magulu a odwala odwala mwapadera

Kwa odwala omwe ali ndi vuto lalikulu kapena zina zoyipa (kuchepa thupi, kuthana, ndi zina zotere), kutumizirana magazi kuyenera kuchitidwa pang'onopang'ono, mwina pochepetsa mlingo wa mankhwalawa kapena powonjezera kuchuluka pakati pa kuchuluka kwa mankhwala.

Gwiritsani ntchito odwala okalamba (woposa zaka 65)

Odwala okalamba nthawi zina amafunika kusankha kwa munthu kuti athandize kuti achepetse matenda a impso (onani Gome 2). Kwa odwala okalamba, kukula kwa kuwodzera, zotumphukira edema ndi asthenia nthawi zambiri kumawonedwa. Gwiritsani ntchito odwala omwe ali ndi impso.

Odwala omwe ali ndi vuto laimpso komanso / kapena odwala hemodialysis amafunikira kusankha kwa mankhwalawa (onani Gome 2). Kwa odwala awa, makapisozi 100 a gabapentin amagwiritsidwa ntchito nthawi zambiri.

Kugwiritsa ntchito kwaumwini pa hemodialysis

Kwa odwala omwe ali ndi anuria omwe akudwala hemodialysis omwe sanalandirepo gabapentin kale, mlingo wokhuthala uyenera kukhala 300-400 mg. Pakadutsa pakulimbikitsa, odwala hemodialysis amapatsidwa 200-300 mg maola 4 aliwonse a hemodialysis. Patsiku lopanda hemodialysis, gabapentin sayenera kumwedwa.

Mankhwala okonza a gabapentin a hemodialysis odwala amatsimikizika potsatira malangizo omwe ali mu Gawo 2. Kuphatikiza pa mlingo wokonzanso, odwala a hemodialysis amalimbikitsidwa kumwa 200 mg wa 200 pakadutsa maola 4 aliwonse.

Zolemba zogwiritsira ntchito

Kukopa pa kuyendetsa magalimoto ndikugwira ntchito ndi makina ndi makina.

Gabapentin atha kukhudza kuyendetsa galimoto komanso makina. Gabapentin amakhudza dongosolo lamkati lamanjenje ndipo amatha kuyambitsa kugona, chizungulire, kapena zizindikiro zina. Chifukwa chake, gabapentin, ngakhale ikagwiritsidwa ntchito monga momwe adanenera, imatha kuchepetsa kuthamanga ndikulepheretsa kuyendetsa magalimoto kapena kugwira ntchito m'mafakitale owopsa. Izi zimachitika makamaka kumayambiriro kwa mankhwalawa ndikuwonjezera mlingo wa mankhwalawo komanso mukamamwa mowa.

Njira zopewera kupewa ngozi

Kukhumudwa ndi kusintha kwamawonedwe kumawonedwa mwa odwala omwe ali ndi antiepileptic mankhwala. Kufufuza kwa meta kovutikira koyeserera kosiyanasiyana, koyesedwa m'malo ndi mankhwala a antiepileptic kwawonetsa kuwonjezeka pang'ono kwa chiopsezo cha malingaliro odzipha komanso machitidwe. Makina a kuwonjezekaku sakudziwika, ndipo zomwe zilipo sizimapatula mwayi wowonjezera chiopsezo chodzipha mukamamwa mankhwala othandizira antiepileptic.

Odwala ayenera kuyang'aniridwa kwambiri kuti athe kuzindikira zizindikiro za kukhumudwa, malingaliro ofuna kudzipha, kapena machitidwe munthawi yake. Ngati zizindikiro za kukhumudwa ndi / kapena malingaliro ofuna kudzipha kapena mawonekedwe atawonekera, odwala ayenera kulangizidwa kuti apite kuchipatala msanga.

Kulekeratu mwadzidzidzi kwa gabapentin sikulimbikitsidwa, chifukwa izi zingapangitse kuchuluka kwa khunyu. Ngati dokotala akukhulupirira kuti mlingo wa mankhwalawa kapena kuchepetsedwa kwa mlingo wake uyenera kukhala pang'onopang'ono ndipo umatha sabata 1.

Gabapentin sichimawoneka chothandiza mankhwalawa.

Monga ma anticonvulsants ena, mwa odwala nthawi zambiri kukomoka kumawonjezeka kapena mitundu yatsopano ya kukomoka imatha kuoneka pakumwa mankhwala a gabapentin.

Kuyesa kuletsa kugwiritsa ntchito mankhwala othandizira antiepileptic kuti musinthe kwa gabapentin monotherapy mwa odwala omwe amalandila angapo antiepileptic mankhwala sikuyenda bwino.

Pogwiritsa ntchito mankhwala a anticonvulsant, kuphatikiza gabapentin, milandu yokhwima yoopsa, yoopsa yokhudza matenda a hypersensitivity, monga DEES'S syndrome (zotupa pakhungu limodzi ndi eosinophilia, malungo komanso zodziwika bwino).

Kuwonetsedwa koyambirira kwa kusintha kwa hypersensitivity, monga fever kapena lymphadenopathy, kumatha kuchitika pamene zotupa sizinafotokozedwe. Ngati zizindikiro zomwe zili pamwambazi zikuwonekera, wodwalayo amayenera kumuyesa dokotala nthawi yomweyo. Ngati sizotheka kukhazikitsa zifukwa zina zomwe zimayambitsa chitukuko cha matendawa, gabapentin iyenera kusiyidwa.

Mukamapereka mankhwala a gabapentin kwa odwala omwe ali ndi matenda a shuga, ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi ndipo ngati kuli kotheka, sinthani mankhwala a hypoglycemic.

Zizindikiro za kapamba zikawoneka, mankhwalawa ayenera kuyimitsidwa.

Pa mankhwala, simungathe kumwa mowa.

Zotsatira zakugwiritsa ntchito kwa nthawi yayitali (kupitirira masabata 36) kwa gabapentin pamaphunziro, luntha, ndi chitukuko mwa ana ndi achinyamata sizinaphunzitsidwe mokwanira.

Zotsatira za mayeso ochepetsa kuchuluka kwa mapuloteni mumkodzo pogwiritsa ntchito timiyeso titha kukhala zabodza. Chifukwa chake, ngati kuli kotheka, ndikulimbikitsidwa kuti mupange mawunikidwe owonjezera pogwiritsa ntchito njira zina (njira ya Biuret, njira ya turbidimetric, zitsanzo ndi utoto).

Gabagamm ili ndi lactose. Odwala omwe ali ndi matenda achilendo, mwachitsanzo, ndi tsankho lactose, kuperewera kwa lappase, glucose - galactose malabsorption, sayenera kumwa mankhwalawa.

Ndemanga pa Gabagamm

Izolda Veselova, wazaka 39, St. Petersburg

Makapisozi a Gabagamma adalembedwa mogwirizana ndi nthambi za neuralgia 2. Dotoloyo anati mlingo wake umakhazikitsidwa kutengera mtundu wa zabwino. M'malo mwanga, ndinayenera kutenga makapisozi 6 patsiku. Iyenera kuchitika mosamala: kumayambiriro kwa mankhwalawa, idayamba ndi makapisozi awiri kwa masiku 7, pambuyo pake mlingowo unakula. Ndimaona kuti ndi njira yothandiza ya kukhudzika. Sindinazindikire zovuta zilizonse panthawi ya chithandizo. Kukokana kunayima.

Dominika Tikhonova, wazaka 34, Rostov-on-Don

Adatenga Gabagamma monga adanenedwa ndi katswiri wazokhudza matenda amitsempha yama bongo. Carbamazepine sanali kuchita bwino pa vuto langali. Makapisozi anathandizira ndimazinthu oyamba. Njira ya mankhwala osokoneza bongo idatenga miyezi itatu kuyambira Meyi Meyi. Ngakhale kuti ali ndi matenda osachiritsika, kupweteka ndi zizindikiro za matenda zidutsa. Chojambula chokha ndicho mtengo. Kwa mabotolo 25 ndinayenera kulipira ma ruble 1200.