Mapiritsi, okhala ndi zokutira kwamafuta oyera, amakhala osatha, ali ndi ngozi, osanunkhiza.

Omwe amathandizira: hypromellose (1500CPS), hypromellose (5CPS), povidone (K25), magnesium stearate, macrogol 6000, titanium dioxide.

Ma PC 10 - matuza (3) - mapaketi a makatoni.
Ma PC 10 - matuza (12) - mapaketi a makatoni.
20 ma PC. - matuza (6) - mapaketi a makatoni.

Oral hypoglycemic mankhwala

Oral hypoglycemic mankhwala ochokera pagulu la Biguanide. Amalepheretsa gluconeogeneis m'chiwindi, amachepetsa mayamwidwe m'matumbo, imathandizira kugwiritsidwa ntchito kwa glucose, komanso imakulitsa chidwi cha minofu kuti insulini. Zisakhudze kubisalira kwa insulin ndi ma cell a kancre.

Lowers triglycerides, LDL.

Imakhazikika kapena kuchepetsa thupi.

Ili ndi fibrinolytic mwina chifukwa chokakamira minofu ya plasminogen activator inhibitor.

Pambuyo pakukonzekera pakamwa, metformin imatengedwa kuchokera m'mimba. Bioavailability mutatenga muyezo mlingo 50-60%. C max pambuyo pakamwa makonzedwe amapezeka pambuyo 2 maola

Sizikugwirizana ndi mapuloteni a plasma. Amadziunjikira mu ndulu zakumaso, minofu, chiwindi, ndi impso.

Amatulutsidwa popanda mkodzo. T 1/2 ndi maola 1.5-4.5.

Pharmacokinetics mu milandu yapadera yamankhwala

Ndi matenda aimpso, kuwonongeka kwa mankhwalawa ndikotheka.

Contraindication Metfogamma 850

- matenda ashuga ketoacidosis, matenda a shuga, chikomokere,

- Zowopsa zaimpso,

- mtima ndi kupuma kulephera, pachimake gawo la kulowerera kwam'mnyewa, kuwonongeka kwa mtima pachimake, kuchepa mphamvu kwa thupi, uchidakwa komanso zina zomwe zingapangitse kukula kwa lactic acidosis,

- lactic acidosis ndi mbiri yake,

- opaleshoni yayikulu ndikuvulazidwa (mu izi, chithandizo cha insulin chimasonyezedwa),

- chiwindi ntchito,

- poyizoni mowa,

- lactic acidosis ndi mbiri yake,

- gwiritsani ntchito osachepera masiku awiri asanafike komanso masiku awiri mutapanga maphunziro a radioisotope kapena x-ray ndikukhazikitsa ma iodine okhala ndi zosiyana pakati,

- kutsatira zakudya zochepa zopatsa mphamvu (zosakwana 1000 cal / tsiku),

- mkaka wa m'mawere (yoyamwitsa),

- Hypersensitivity ku zigawo za mankhwala.

Sitikulimbikitsidwa kugwiritsa ntchito mankhwalawa odwala omwe ali ndi zaka zopitilira 60 omwe amagwira ntchito zolimbitsa thupi, chifukwa chowonjezera chiopsezo cha lactic acidosis.

Mlingo ndi kayendetsedwe ka Metfogamm 850

Khazikikani payekhapayekha, poganizira kuchuluka kwa shuga m'magazi.

Mlingo woyambirira nthawi zambiri umakhala 850 mg (1 tabu.) / Tsiku. Kuwonjezereka kwapang'onopang'ono kwa mlingo kumatheka kutengera mphamvu ya mankhwala. Mlingo wokonza ndi 850-1700 mg (mapiritsi 1-2) / tsiku. Mlingo wambiri watsiku ndi tsiku ndi 2550 mg (mapiritsi atatu).

Mlingo wa tsiku ndi tsiku wopitirira 850 mg tikulimbikitsidwa mu Mlingo 2 wogawanika (m'mawa ndi madzulo).

Odwala okalamba, mlingo woyenera sayenera kupitirira 850 mg / tsiku.

Mapiritsi amayenera kumwedwa ndi chakudya chonse, kutsukidwa ndi madzi pang'ono (kapu yamadzi).

Mankhwalawa adapangira kuti azigwiritsa ntchito kwa nthawi yayitali.

Chifukwa chowonjezera chiopsezo cha lactic acidosis, mu zovuta zazikulu za metabolic, mlingo uyenera kuchepetsedwa.

Zotsatira zoyipa Metphogamm 850

Kuchokera pamimba: kukhumudwa, kusanza, kupweteka kwam'mimba, kutsegula m'mimba, kusowa kwa chakudya, zotsekemera pakamwa siziyenera kuimitsidwa, ndipo zizindikiro zimatha paokha osasinthanso mlingo wa mankhwalawa, pafupipafupi komanso kuwopsa kwa zovuta zake kumatha kuchepetsedwa pang'onopang'ono. Mlingo wa metformin), kawirikawiri - kupatuka kwa maselo a chiwindi, hepatitis (kudutsa atasiya mankhwala).

Thupi lawo siligwirizana: zotupa pakhungu.

Kuchokera ku endocrine system: hypoglycemia (mukamagwiritsa ntchito mankhwala osakwanira).

Kuchokera kumbali ya kagayidwe: kawirikawiri - lactic acidosis (imafuna kuleka kwa chithandizo), ndikugwiritsa ntchito nthawi yayitali - hypovitaminosis B 12 (malabsorption).

Kuchokera pa hemopoietic dongosolo: nthawi zina - megaloblastic anemia.

Zizindikiro: fatact lactic acidosis imayamba. Zomwe zimayambitsa kukula kwa lactic acidosis amathanso kukhala cumulation wa mankhwalawa chifukwa cha kuwonongeka kwa impso. Zizindikiro zoyambirira za lactic acidosis ndi mseru, kusanza, kutsegula m'mimba, kutsitsa kutentha kwa thupi, kupweteka kwam'mimba, kupweteka kwa minofu, mtsogolomo kumatha kuwonjezera kupuma, chizungulire, chikumbumtima chosautsa komanso kugona.

Chithandizo: ngati pali zizindikiro za lactic acidosis, chithandizo ndi Metfogamma 850 ziyenera kuyimitsidwa nthawi yomweyo, wodwalayo ayenera kuchipatala mwachangu ndipo, atatsimikiza kuti ali ndi lactate, atsimikizireni matendawa. Hemodialysis imathandiza kwambiri pochotsa lactate ndi metformin m'thupi. Ngati ndi kotheka, chitani mankhwala othandizira.

Mankhwala ophatikiza ndi sulfonylureas, hypoglycemia imayamba.

Pogwiritsa ntchito munthawi yomweyo ndi sulfonylurea zotumphukira, ma acarbose, insulin, NSAIDs, ma inhibitors a MAO, oxytetracycline, ma inhibitors a ACE, clofibrate zotumphukira, cyclophosphamide ndi beta-blockers, ndizotheka kuwonjezera mphamvu ya hypoglycemic ya metformin.

Pogwiritsa ntchito munthawi yomweyo ndi GCS, kulera kwapakamwa, epinephrine (adrenaline), sympathomimetics, glucagon, mahomoni a chithokomiro, thiazide ndi loopback diuretics, phenothiazine zotumphukira ndi nicotinic acid, kuchepa kwa mphamvu ya hypoglycemic ya metformin ndikotheka.

Cimetidine amachepetsa kuchotsedwa kwa metformin, chifukwa chomwe chiopsezo cha lactic acidosis chikuwonjezeka.

Metformin itha kufooketsa mphamvu ya ma anticoagulants (zotumphukira za coumarin).

Ndi munthawi yomweyo makonzedwe ndi Mowa, kukula kwa lactic acidosis ndikotheka.

Ndi munthawi yomweyo kugwiritsa ntchito nifedipine kumathandizira mayamwidwe a metformin, C max, amachepetsa kuchotsa.

Mankhwala a Cationic (amlodipine, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren, vancomycin) omwe amatulutsidwa m'mapikisano olimbana ndi machitidwe ogwiritsira ntchito ma tubular ndipo, ngati atachira, amatha kuonjezera C maxformform ndi 60%.

Munthawi yogwiritsira ntchito mankhwalawa, zizindikiro za impso ziyenera kuyang'aniridwa. Osachepera 2 pachaka, komanso maonekedwe a myalgia, zomwe zimakhala mu plasma ziyenera kutsimikiziridwa.

Ndikotheka kugwiritsa ntchito Metfogamma ® 850 kuphatikiza ndi zotumphukira za sulfonylurea kapena insulin, makamaka kuwunika kwamisempha yamagazi ndikofunikira.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Mukamagwiritsidwa ntchito ngati monotherapy, mankhwalawa sasokoneza luso loyendetsa magalimoto ndikugwira ntchito ndi zida.

Metformin ikaphatikizidwa ndi mankhwala ena a hypoglycemic (sulfonylurea derivatives, insulin), mikhalidwe ya hypoglycemic imatha kukhala ndi kuthekera kwakutha kuyendetsa magalimoto ndi zochitika zina zowopsa zomwe zimafuna chidwi chochulukirapo komanso kuthamanga kwa zochitika zama psychomotor.

Mankhwalawa amayenera kusungidwa kuti ana asawatenthe pa kutentha osaposa 25 ° C. Moyo wa alumali ndi zaka 4.

Metfogamm 1000: malangizo ogwiritsira ntchito, mtengo, mapiritsi a shuga

Matenda a shuga ndi matenda a kagayidwe kamene kamayambitsa matenda a hyperglycemia. Matenda a shuga ndi amtundu wa 2 - wodalira insulin komanso osadalira insulini.

Kutengera kwa chibadwa, kudya kosasamala, kunenepa kapena zina zomwe zimagwirizanitsidwa zimatha kutsogolera matendawa. Pochiza matenda osokoneza bongo omwe amadalira matenda a shuga, mankhwalawa amagwiritsidwa ntchito omwe ali ndi vuto la hypoglycemic.

Chimodzi mwa mankhwala abwino kwambiri amtunduwu ndi mapiritsi a Metphogamm. Gawo lomwe limagwiritsa ntchito mankhwalawa ndi metformin. Mankhwalawa amapezeka mosiyanasiyana. Zodziwika kwambiri ndi 850 ndi 1000 mg. Metphogamm 500 imagulitsidwanso m'masitolo ogulitsa mankhwala.

Kodi mankhwalawo ndi angati? Mtengo umatengera kuchuluka kwa metformin pamankhwala. Kwa Metfogamma 1000 mtengo ndi 580-640 rubles. Metfogamm 500 mg imawononga ndalama pafupifupi 380-450 rubles. Pa Metfogamma 850 mtengo umayambira ku ruble 500. Ndikofunika kudziwa kuti mankhwalawa amaperekedwa pokhapokha ngati mwalandira mankhwala.

Amapanga mankhwala ku Germany. Ofesi yoimira boma ili ku Moscow. Mu 2000s, kupanga mankhwala kunakhazikitsidwa mumzinda wa Sofia (Bulgaria).

Kodi mfundo yokhudza kugwiritsa ntchito mankhwala osokoneza bongo ndi iti? Metformin (gawo lomwe limagwiritsa ntchito mankhwalawa) amachepetsa kuchuluka kwa shuga m'magazi. Izi zimatheka ndikupondereza gluconeogenesis m'chiwindi. Metformin imathandizanso kugwiritsidwa ntchito kwa glucose mu minofu ndikuchepetsa kuyamwa kwa shuga kuchokera m'mimba.

Ndizofunikira kudziwa kuti mukamagwiritsa ntchito mankhwalawa, kuchuluka kwa cholesterol ndi LDL mu seramu yamagazi kumachepetsedwa. Koma Metformin sikusintha kuchuluka kwa lipoproteins. Mukamagwiritsa ntchito mankhwalawa mutha kuchepetsa thupi. Mwachilengedwe, 500 mg 850, ndi 100 mg metogram amagwiritsidwa ntchito pamene kudya sikumathandiza kuchepetsa thupi.

Metformin samangoyendetsa shuga wamagazi, komanso imakweza kwambiri magazi a fibrinolytic.

Izi zimatheka ndikupondereza mtundu wa plasminogen inhibitor.

Kodi kugwiritsa ntchito mankhwalawa a Metfogamm 500 kulungamitsidwa nthawi ziti? Malangizo ogwiritsira ntchito akuti mankhwalawa amayenera kugwiritsidwa ntchito pochiza matenda ashuga a 2 omwe samatengera insulin. Koma Metfogamma 1000, 500 ndi 800 mg ayenera kugwiritsidwa ntchito pochiza odwala omwe samakonda ketoacidosis.

Momwe mungamwe mankhwalawo? Mlingo wake umasankhidwa molingana ndi kuchuluka kwa shuga m'magazi. Nthawi zambiri, mlingo woyambira ndi 500-850 mg. Ngati mankhwalawa amagwiritsidwa ntchito kuti azikhala ndi shuga wamba, ndiye kuti tsiku lililonse mlingo ungakulitse mpaka 850-1700 mg.

Muyenera kumwa mankhwalawa Mlingo 2 wogaŵanika. Kodi ndiyenera kumwa mankhwalawo kwa nthawi yayitali bwanji? Kwa Metfogamma 850, malangizowo samawongolera kutalika kwa mankhwalawa. Kutalika kwa chithandizo kumasankhidwa payekha ndipo zimatengera zinthu zambiri.

Mu Metfogamma 1000, malangizo ogwiritsira ntchito amawongolera zotsutsana zotere kuti mugwiritse ntchito:

• Matenda a shuga ketoacidosis.
• Kusokonekera mu ntchito ya impso.
• Kulephera kwa mtima.
• Cerebrovascular ngozi.
• Uchidakwa wambiri
• Kuthetsa madzi m'thupi.
• The pachimake gawo la myocardial infarction.
• Kuchepa kwa chiwindi.
• Poizoni woledzera.
• Lactic acidosis
• Mimba
• Nthawi yonyamula.
• Allergy to metformin ndi zigawo zothandizira za mankhwalawa.

Kuwona kwa madotolo kumawonetsa kuti mankhwalawa sayenera kugwiritsidwa ntchito pakudya kochepa kalori, komwe kumaphatikizapo kumwa zosakwana calories 1000 patsiku. Kupanda kutero, mankhwalawa Metfogamma 1000 amatha kubweretsa zovuta zazikulu, mpaka chifuwa cha matenda ashuga.

Mankhwala nthawi zambiri amavomerezedwa ndi odwala. Koma ndimakonda kugwiritsa ntchito mankhwalawa.

1. Megaloblastic anemia.
2. Kuphwanya munjira yogaya chakudya. Metfogamma 1000 ingayambitse kukula kwa zizindikiro za dyspeptic, nseru, kusanza ndi kutsekula m'mimba. Komanso pakuthandizira mankhwalawa, kulawa kwazitsulo kumatha kuwonekera pakamwa.
3. Hypoglycemia.
4. Lactic acidosis.
5. Thupi lawo siligwirizana.

Kukula kwa lactic acidosis kumawonetsa kuti ndikwabwino kusokoneza njira yamankhwala.

Vutoli likachitika, chithandizo chamankhwala chiyenera kutengedwa nthawi yomweyo.

Kodi metfogamma 1000 imagwirizana bwanji ndi mankhwala ena? Malangizowo akuti mankhwalawa amatha kuchepetsa chithandizocho pogwiritsa ntchito anticoagulants.

Sitikulimbikitsidwa kugwiritsa ntchito mankhwala a shuga limodzi ndi Mao inhibitors, ACE inhibitors, exofibrate zotumphukira, cyclophosphamides kapena beta-blockers. Ndi kulumikizana kwa metformin ndi mankhwala omwe ali pamwambawa, chiopsezo chowonjezeka cha hypoglycemic chikuwonjezeka.

Ndi ma fanizo opambana kwambiri a Metfogamm 1000? Malinga ndi madotolo, njira zabwino kwambiri ndi izi:

• Glucophage (ma ruble 220-400). Mankhwalawa ali bwino ngati Metfogamm. Gawo lomwe limagwiritsa ntchito mankhwalawa ndi metformin. Mankhwalawa amathandizira kuchepetsa magazi a magazi ndikuwonjezera chidwi cha zotumphukira za insulin.
• Glibomet (ma ruble a 320-480). Mankhwala tikulephera lipolysis mu adipose minofu, kumalimbikitsa mphamvu zotumphukira zimakhala kuti zochita insulin ndipo amachepetsa shuga.
• Siofor (380-500 rubles). Mankhwala amalepheretsa kuyamwa kwa shuga m'matumbo, amathandizira kugwiritsa ntchito shuga m'matumbo a minofu ndikuchepetsa kupanga kwa shuga m'chiwindi.

Mankhwalawa omwe ali pamwambawa amalimbikitsidwa kuti agwiritsidwe ntchito ndi mtundu wachiwiri wa matenda osokoneza bongo a insulin. Mukamasankha analogue, muyenera kufunsa dokotala, chifukwa mankhwalawa ochepetsa shuga amatha kuyambitsa lactic acidosis. Kanemayo munkhaniyi akupitiliza mutu wakugwiritsa ntchito Metformin pa matenda ashuga.

1. 
   Berger M., Starostina EG, Jorgens V., Dedov I. Mchitidwe wa insulin, Springer, 1994.
2. 
   Vasyutin, A. M. Bweretsani chisangalalo cha moyo, kapena Momwe mungachotsere matenda ashuga / A.M. Vasyutin. - M: Phoenix, 2009 .-- 224 p.
3. 
   Balabolkin M.I. Endocrinology. Moscow, yosindikiza nyumba "Mankhwala", 1989, 384 pp.
4. Bulynko, S.G. Zakudya zamankhwala komanso zakudya zamagulu a kunenepa kwambiri komanso matenda a shuga / S.G. Bulynko. - Moscow: Russia State Humanitarian University, 2004. - 256 p.

Ndiloleni ndidziwitse. Dzina langa ndi Elena. Ndakhala ndikugwira ntchito ya endocrinologist kwa zaka zoposa 10. Ndikukhulupirira kuti pakadali pano ndili katswiri pantchito yanga ndipo ndikufuna kuthandiza alendo onse omwe amapezeka pamalowo kuti athetse zovuta osati ntchito. Zinthu zonse za tsambalo amazisonkhanitsa ndikuzikonza mosamala kuti athe kufotokoza zambiri zofunikira. Musanagwiritse ntchito zomwe zikufotokozedwa pa webusaitiyi, kufunsana ndi akatswiri ndizofunikira nthawi zonse.

Kutulutsa mafomu ndi kapangidwe kake

Mapiritsi ozungulira, omwe amaphatikizidwa ndi filimu ndipo alibe fungo lenileni la piritsi. Chofunikira chachikulu ndi metformin hydrochloride 850 mg. Zowonjezera: sodium carboxymethyl wowuma, silicon dioxide, magnesium stearate, chimanga wowuma, povidone, hypromellose, macrogol 6000, titanium dioxide, talc, propylene glycol.

Mapiritsi amadzaza matuza, zidutswa 10 chilichonse. Phukusi la makatoni lili ndi matuza 3, 6 kapena 12 ndi malangizo a mankhwalawo. Palinso mapaketi okhala ndi mapiritsi 20 mchimake. M'katoni 6 matuza otere amadzaza.

Zotsatira za pharmacological

Mankhwala ndi a gulu la Biguanides. Ndi mankhwala a hypoglycemic omwe amapangidwira pakamwa.

Chithandizo chogwira ntchito chimathandizira kulepheretsa kwa gluconeogeneis, omwe amapezeka m'maselo a chiwindi. Kuperewera kwa shuga m'magazi am'mimba kumachepetsedwa, ndipo kugwiritsidwa ntchito kwake mu minofu yamipweya kumangokulira. Kuzindikira kwa minofu kuti insulin iwonjezeke.

Metfogamma ndi m'gulu la Biguanides. Ndi mankhwala a hypoglycemic omwe amapangidwira pakamwa.

Chifukwa chogwiritsa ntchito mapiritsi, kuchuluka kwa ma triglycerides ndi lipoproteins kumachepa. Nthawi yomweyo, kulemera kwa thupi kumakhala kochepa ndipo kumakhala koyenera kwa nthawi yayitali. Mankhwala amalepheretsa zochita za zoletsa wa plasminogen activator, zomwe zimapangitsa kuti mankhwala atchulidwe ka fibrinolytic.

Pharmacokinetics

Metformin imalowetsedwa kuchokera kumimba yokumba pakanthawi kochepa. Bioavailability ndi kuthekera kumangiriza mapuloteni amwazi ndizochepa.Mankhwala ochuluka kwambiri m'madzi a m'magazi amawonedwa patatha maola angapo. Mankhwalawa amatha kudziunjikira minofu ya minyewa, chiwindi, gland ndi impso. Excretion imachitika pogwiritsa ntchito impso kusefedwa, popanda kusintha. Kuchotsa theka-moyo ndi 3 maola.

Contraindication

Pali zotsutsana zingapo pamene mankhwalawa sangathe kugwiritsidwa ntchito:

• Hypersensitivity zigawo zikuluzikulu,
• matenda ashuga ketoacidosis,
• matenda a shuga
• chikomokere
• kuwonongeka kwaimpso,
• kulephera kwa mtima ndi kupuma,
• lactic acidosis
• mimba
• Nthawi yonyamula mkaka
• othandizira opaleshoni
• chiwindi ntchito,
• poyizoni wazakumwa zoledzeretsa,
• radiology yosiyanitsa masiku awiri isanayambe kapena itatha mankhwala,
• kutsatira zakudya zochepa zama calorie.

Sichikulimbikitsidwa kugwiritsa ntchito kwa anthu azaka zopitilira 60 ogwila ntchito yayikulu, angayambitse lactic acidosis.

Matumbo

Matenda a dongosolo logaya chakudya: kutsegula m'mimba, kusanza, kusanza, kupweteka m'mimba, kulawa kwazitsulo pamkamwa, kutsekemera. Zizindikiro izi zimatha patatha masiku ochepa okha.

Pogwiritsa ntchito kwa nthawi yayitali mankhwala a Medfogamm 850 kapena kuwonongeka kwa mankhwalawa, zotsatira zingapo zovuta zimachitika zomwe zimafuna kusintha kwa mankhwalawa kapena kusinthira mankhwalawa.

Kuchokera kumbali ya kagayidwe

Lactic acidosis, hypovitaminosis komanso kuyamwa kwa vitamini B12.

Nthawi zina, thupi limagwidwa ngati zotupa pakhungu.

Amayi oyembekezera omwe ali ndi matenda a shuga a 2 sayenera kuthandizidwa ndi metformin.

Gwiritsani ntchito pa nthawi yoyembekezera

Amayi oyembekezera omwe ali ndi matenda a shuga a 2 sayenera kuthandizidwa ndi metformin. Kukhalabe ndi glucose wamba, insulin ina imachitika. Izi zimachepetsa chiopsezo kwa mwana wosabadwayo.

Chithandizo chogwira msanga chimapita mkaka wa m'mawere, zomwe zimatha kusokoneza thanzi la mwana. Chifukwa chake, kwa nthawi ya mankhwala, ndibwino kusiya kuyamwitsa.

Gwiritsani ntchito mu ukalamba

Zimafunika kusamala, chifukwa anthu azaka zopitilira 65 ali pachiwopsezo chachikulu cha kukhala ndi hypoglycemia, lactic acidosis, matenda aimpso, chiwindi ndi mtima. Chifukwa chake, mlingo uyenera kusinthidwa kwa wodwala aliyense payekhapayekha, poganizira kuyambika kwa zovuta za matenda ashuga.

Mankhwala a Metfogamma 850 ali osavomerezeka kwa ana ochepera zaka 10.

Zokhudza mphamvu pakuwongolera njira

Pogwiritsa ntchito mapiritsi molumikizana ndi othandizira ena a hypoglycemic, zizindikiro za hypoglycemia zitha kuchitika, zomwe zimakhudza kuthamanga kwa zochitika zama psychomotor komanso ndende. Chifukwa chake, kwa nthawi ya mankhwalawa, ndibwino kukana kuyendetsa paokha.

Kugwiritsa ntchito kwa vuto la chiwindi

Mapiritsi angagwiritsidwe ntchito pokhapokha ngati pali kufooka kwa chiwindi. Pakulephera kwambiri kwa chiwindi, mankhwala ndi oletsedwa.

Kulephera kwambiri kwa chiwindi, kutenga Metfogamma ndi koletsedwa.

Mankhwala ochulukirapo a Metfogamm 850

Mukamagwiritsa ntchito Metfogamm pa mlingo wa 85 g, palibe zizindikiro za bongo zomwe zimawonedwa. Ndi kuwonjezeka kwa mlingo wa mankhwalawa, kukula kwa hypoglycemia ndi lactic acidosis ndikotheka. Pankhaniyi, kuyipa kwakusaku. Pambuyo pake, wodwalayo amatha kukhala ndi malungo, kupweteka m'mimba ndi mafupa, kupumira mwachangu, kusowa chikumbumtima komanso chikomokere.

Zizindikirozi zikawoneka, mankhwalawo amasiya pomwepo, wodwala amapezeka kuchipatala. Mankhwala amachotsedwa m'thupi ndi hemodialysis.

Kuchita ndi mankhwala ena

Pogwiritsa ntchito munthawi yomweyo kugwiritsa ntchito mankhwala ambiri a sulfonylurea, insulin, MAO ndi ACE zoletsa, cyclophosphamide, mankhwala osokoneza bongo a anti-yotupa, zotumphukira zotumphukira, ma tetracyclines komanso ma beta-blockers, zotsatira za hypoglycemic zimagwiritsidwa ntchito.

Glucocorticosteroids, sympathomimetics, epinephrine, glucagon, ma OC ambiri, mahomoni a chithokomiro, diuretics ndi zotumphukira za nicotinic acid zimapangitsa kuchepa kwa vuto la hypoglycemic.

Cimetidine amachedwetsa kuyamwa kwa metformin, yomwe nthawi zambiri imabweretsa kukula kwa lactic acidosis. Chithandizo chogwiritsidwa ntchito chimafooketsa mphamvu yogwiritsira ntchito ma anticoagulants, makamaka a coumarin.

Nifedipine imawonjezera mayamwidwe, koma imachepetsa kuchotsedwa kwa zinthu zogwira ntchito mthupi. Digoxin, morphine, Quinine, Ranitidine ndi Vancomycin, omwe amatsekeredwa makamaka m'matumba, ndimankhwala omwe amapezeka nthawi yayitali amawonjezera nthawi ya mankhwala.

Kuyenderana ndi mowa

Zakumwa zoledzeretsa sizingaphatikizidwe ndi zakumwa zoledzeretsa, monga mogwirizana ndi ethanol amalimbikitsa kukula kwa lactic acidosis.

Mapiritsi a Metphogamma sangaphatikizidwe ndi zakumwa zoledzeretsa, monga mogwirizana ndi ethanol amalimbikitsa kukula kwa lactic acidosis.

Pali mankhwala omwe alowa m'malo omwe ali ndi kufanana pakapangidwe kake:

• Bagomet,
• Glycomet
• Glucovin,
• Chikwanje,
• Glumet
• Dianormet 1000,500,850,
• Diaformin,
• Insulor,
• Langerin
• Meglifort
• Meglucon
• Metamine
• Metformin Hexal,
• Metformin Zentiva,
• Metformin Sandoz,
• Metformin Teva,
• Metformin
• Panfort
• Siofor
• Zucronorm,
• Emnorm Er.

Madokotala amafufuza

Minailov AS, wazaka 36, ​​wazachipatala wa ku endocrinologist, ku Yekaterinburg: "Nthawi zambiri ndimasankha Metphogamma kukhala odwala matenda ashuga onenepa kwambiri 850. Amasunga shuga bwino. Ndi yabwino kutenga, monga Mlingo wa tsiku lililonse amatengedwa 1 nthawi. Mtengo wotsika mtengo, anthu amatha kulipirira. ”

Pavlova MA, wazaka 48, wodziwika za endocrinologist, Yaroslavl: "Ndimayesetsa kutsogoza metfogam mosamala. Mankhwala amakumana ndi zovuta, sikuti nthawi zonse amaloledwa ndipo nthawi zina amayambitsa zosafunikira. Ngati matenda ena aliwonse akamakula pa nthawi ya mankhwalawa, ndimatha kumwa mankhwalawo. ”

Ndemanga za Odwala

Roman, wazaka 46, Voronezh: “Zaka zingapo zapitazo ndinapezeka ndi matenda a shuga. Metphogamm 850 idalembedwa mapiritsi nditatha kuyesera mankhwala ena angapo, ndipo sanasunge shuga. Ndikhutira ndi zomwe zachitika. ”

Oleg, wazaka 49, Tver: "Ndakhala ndikumwa mankhwalawo kwa theka la chaka kale. Kusanthula ndi kwabwinobwino. Komabe, ndimayendera pafupipafupi endocrinologist, chifukwa ngakhale "chimfine" cha banal chimatha kuyambitsa mavuto ambiri mukamamwa mankhwalawa. "

Ndemanga za kuchepetsa kunenepa

Katerina, wazaka 34, ku Moscow: “Malingana ngati sindimangopanga zakudya, sikokwanira kuti ndichepetse thupi, koma ndi kulemera kwambiri, sikunali kutali ndi matenda a shuga. Dotolo adatumiza mankhwalawa m'mapiritsi - Metfogamma 850. Poyamba zonse zidayenda bwino, koma patatha miyezi ingapo impso zanga zidayamba kupweteka. Ndinaleka kumwa mankhwalawa ndikubwereranso pachakudya. Ndidatsimikizira ndekha kuti mankhwalawa amafunika kuti odwala matenda ashuga azikhala ndi shuga, osatinso kuchepetsa thupi. ”

Metformin: malangizo ogwiritsira ntchito kuchepa thupi

Poyamba, Metformin poyambirira adapangidwa kuti azithandiza odwala omwe ali ndi matenda a shuga mellitus. Pambuyo pake, pophunzira za mankhwalawa, zisonyezo zina zidawululidwa, mwachitsanzo, chithandizo cha kunenepa kwambiri komanso kunenepa kwambiri. Koma kodi ndiwothandiza kwa anthu onenepa kwambiri opanda matenda ashuga? Kuti tichite izi, tiyenera kumvetsetsa momwe mankhwalawa amagwirira ntchito komanso chifukwa chake kunenepa kwambiri kumachitika.

Ngati mukufuna kuphunzira mokwanira machitidwe onse a metformin, ndikupangira kuti muwerenge kaye nkhani yowunika "Metformin: momwe imagwirira ntchito." Munkhaniyi sindiyankhula za zonse zomwe zilipo, koma ndingolankhula zokhudzana ndi kuchepa thupi.

Chifukwa cha zomwe metformin "imathandizira" kuchepa thupi

Ndinganene motsimikiza 99% kuti pafupifupi anthu onse onenepa kwambiri amakhala ndi vuto la kusamva bwino kwa insulin pakapita nthawi. Insulin ndi timadzi tating'onoting'ono tokhala ndi glucose m'maselo. Pazifukwa zina, maselo samalowanso insulin ndipo glucose sangathe kulowa m'maselo. Zotsatira zake, ziphuphu zimapatsidwa chizindikiro kuti ziwonjezere kupanga kwa insulin ndipo zimayamba kulowa m'magazi.

Izi zimapangitsa kuti mafuta asamale kwambiri, chifukwa kusungidwa kwamafuta kumakhala kosavuta komanso mwachangu. Zomwe zimapangitsa kuti maselo asiye kumva kuti ali ndi insulin yambiri, koma ochulukirapo amakhala ndi mafuta ochulukirapo. Maselo amadzaza ndi shuga ndipo amayesa kuzimitsa osazindikira insulin. Zinafika poti insulini nthawi zambiri sili ndi mlandu uliwonse, chifukwa adangochita ntchito yake.

Zotsatira zake, zimachulukirachulukira, ndipo zimayamba kuchuluka, zimadana kwambiri ndi maselo amthupi. Likukhalira kuzungulira koyipa komwe kumabweretsa kunenepa kwambiri, kukana insulini ndi hyperinsulinism.

Metformin imakhudzana ndi zotumphukira za insulin, ndikuchepetsa ndikubwerera mulingo wake wachilengedwe. Izi zimabweretsa kuyamwa kwabwinobwino kwa glucose ndi maselo ndipo sikulola kuti insulini ipangidwe mwambiri, zomwe zimatanthawuza kusunga mafuta.

Mwachidule, metformin imagwira ntchito pochita zina mwa insulin pochotsa insulin. Kuphatikiza apo, metformin imakhala yofooka yothandizanso - kuchepetsa kulakalaka (anorexigenic athari). Ndi zomwe aliyense amaganiza za iye akayamba kumwa mankhwalawo.

Komabe, izi ndizofooka kwambiri kotero kuti sizimamvekanso ndi aliyense. Chifukwa chake dalirani izi, kutali kwambiri, zotsatira za mankhwalawo sizoyenera.

Kodi ikhoza kuchepetsa kulemera ndi metformin: kuwerengetsa kwa dotolo

Ngakhale kutsitsa shuga kochepa, chifukwa chakuti kumalimbikitsa kuyamwa kwa shuga ndi maselo, metformin sikuti nthawi zonse imabweretsa kuwonda. Ndinganene kuti izi ndizosowa kwambiri ndipo sizifotokozedwa.

Ngati mukuganiza kuti kumwa mapiritsi awiri patsiku, koma osachita zina zilizonse kuti muchepetse kunenepa, mumataya mafuta 30 makilogalamu, ndiye ndiyenera kukukhumudwitsani. Metformin ilibe katundu. Zabwino kwambiri pamenepa mungotaya mapaundi ochepa.

Ndipo momwe mungatengere metformin kuti muchepetse kunenepa

Kumbukirani kuti metformin sindiwo mapiritsi amatsenga omwe amathetsa ma kilogalamu anu mozizwitsa, ndipo pakadali pano mukudya mkate wachikhumi womwe uli pa sofa. Ndi njirayi, palibe chida chomwe chidzagwira ntchito. Kusintha kofananirako kwa moyo wanu, komwe kumaphatikizapo zakudya, kuyenda ndi malingaliro, zomwe zimatha kubweretsa zotsatira zenizeni.

Titha kunena kuti moyo watsopano ndi wofunikira kwambiri, ndipo metformin imangothandiza. Mankhwalawa siwopanda ndipo nthawi zambiri mungathe kuchita popanda iwo. Izi sizikugwira ntchito pazomwe zimalemera kwambiri komanso shuga. Koma ngati muli ndi kunenepa kwambiri komanso popanda matenda ashuga, zimakhala bwino kumangokhala m'maganizo kuti mupewe mapiritsi, ndiye kuti muchite bwino.

Ndi metformin iti kuti musankhe? Metformin Richter kapena Metformin Teva, ndipo mwina Metformin Canon

Pakadali pano, pamsika wamankhwala pali makampani ambiri omwe amapanga mapiritsi otere. Mwachilengedwe, kampani iliyonse imatulutsa metformin pansi pa dzina la malonda, koma nthawi zina amatchedwanso "Metformin", mathero amangowonjezeredwa omwe amawonetsa dzina la kampaniyo. Mwachitsanzo, metformin-teva, metformin-canon kapena metformin-richter.

Palibe kusiyana kwakukulu mu mankhwalawa, chifukwa chake mutha kusankha iliyonse. Ndingonena kuti ngakhale pali zinthu zomwezo, zina zowonjezera zingakhale zosiyanasiyana ndipo pazomwe zimachitika zimatha kuwonedwa, ngakhale metformin imakhalanso ndi zovuta. Werengani nkhani yomwe ndidalimbikitsa pamwambapa.

Momwe mungamwe metformin kuti muchepetse thupi

Muyenera kuyamba ndi mlingo wa 500 mg kamodzi. Mankhwalawa ali ndi mitundu yosiyanasiyana - 500.850 ndi 1000 mg. Ngati mukufuna kuyamba ndi mlingo waukulu, mudzamva kukongola konse kwamatenda oyipa, omwe amakhala makamaka amisala osokoneza bongo kapena, ku Russia, matenda am'mimba. Onjezani mlingo pang'onopang'ono ndi 500 mg pa sabata.

Mlingo wambiri watsiku ndi tsiku umatha kukhala 3,000 mg, koma monga lamulo, madokotala ndi ine pakati pawo ali ndi malire a 2000 mg. Kupitilira kuchuluka kumeneku, kugwirako ntchito kumakhala kochepa, ndipo mavuto ake akuwonjezeka.

Mankhwala amatengedwa nthawi ya chakudya kapena itatha. Amalembedweratu asanagone - mankhwalawa alinso olondola ndipo ali ndi malo oti akhale. Zotsatira zoyipa zikaoneka ndipo sizinadutse pambuyo pa masabata awiri kuyambira pomwe munayambira, ndiye kuti mankhwalawa siabwino kwa inu ndipo ayenera kusiyidwa.

Metformin: kuwunika kwa kunenepa

Sindinali waulesi kwambiri ndipo ndinakwera pamagulu ndi malo omwe kulumikizana pakati pa kuchepetsa thupi ndi komwe amagawana zomwe akumana nazo. Pempholi lidatulutsa mphamvu ya metformin. Ndikukupatsirani ndemanga zenizeni za anthu kuti musawafunse pamaneti. Ndemanga zambiri sizabwino. Zomwe zimakhala zabwino nthawi zambiri zimalimbikitsa mtundu wina wa mankhwala kapena kugwiritsa ntchito njira zina kupatula metformin. Ine sindinalamulire ndemanga; zitha kukhala ndi zolakwika zosiyanasiyana.

Unikani Na. 1 (pakutsimikizira mawu anga)

Mverani, ngati mumatsatira malangizo olimbitsa thupi mu metformin .. ndiye kuti metformin palokha siyofunika)))))))))))

Unikani Na. 2 (osati onse odwala matenda ashuga)

Mayi anga, omwe ali ndi matenda ashuga, amamwa metformin. Ndipo china chake sachepa naye. = -))))))))) Chinyengo china.

Unikani Na. 3 (zotsatira z zero ndi zotsatiranso, chinthu chachikulu ndikubweretsa mawu)

Ndinaganiza z kumwa Metformin kuti muchepetse thupi, chifukwa amati imaletsa chakudya. Ndinkamwa mogwirizana ndi malangizo, pang'onopang'ono ndikuwonjezera muyezo. Ndiyenera kunena nthawi yomweyo kuti sindimadwala matenda ashuga kapena matenda aliwonse kuti ndizinena motsimikiza. Ndipo, zoona zake, sindinazindikire zotsatira pambuyo pa mwezi umodzi. Winalemba kuti ali ndi zovuta zake, kuti mutha kudwala ngati mumamwa osapangana naye. Chilichonse chinali bwino ndi ine, kapena m'malo mwake, mwanjira iliyonse - kuti ndinamwa zomwe sindinachite. Mwina ili ngati mankhwala, koma kuchepa thupi - 0. Chifukwa chake sindinganene motsimikiza kuti ndiyenera kutero kapena ayi. Koma pofuna kuchepetsa thupi, ayi.

Unikani Na. 4 (zidakumana ndi zovuta)

Inemwini, njirayi sinali yoyenera kwa ine, mavuto anga amatumbo, komanso nseru sizinayende ngakhale mlingo utachepa, ndinasokoneza maphunziro. Palibenso kuyesera.

Unikani Na. 5 (sagwira ntchito popanda chakudya)

Ndinkamwa molingana ndi zidziwitso zachipatala ndipo sindinachepetse thupi popanda kudya. ndi zakudya, inde, ndachepa, koma glucophage alibe chochita ndi izo

Chifukwa chake, ndikuganiza kuti aliyense adamvetsetsa kuti kukonzekera kwa metformin si piritsi labwino kapena zakudya zowonjezera zatsopano, osati owotchera mafuta, osati othandizira mafuta m'matumbo, koma mankhwala akulu omwe ali ndi zisonyezo zachindunji. Ndipo lingaliro lalikulu lomwe ndimafuna kuti ndikufotokozereni kuti metformin sithandiza popanda kusintha kadyedwe, koma monga mankhwala ena kuthana ndi kunenepa kwambiri. Ndi metformin komanso moyo watsopano, kuchepa thupi kumakhala kosangalatsa, m'njira zina kumakhala kosavuta.

Ndipo popeza pali mwayi wopeza zotsatira popanda mankhwala, ndiye kuti simukuyenera kuyamba kumwa metformin nthawi yomweyo? Chemistry yocheperako imatanthawuza thanzi lochulukirapo! Ndizo zonse. Amvera kulandira zolemba zatsopano ndi maimelo ndikudina mabatani azama media pansipa.

Ndi chisangalalo ndi chisamaliro, endocrinologist Lebedeva Dilyara Ilgizovna

* Zambiri sizigwira ntchito kwa anthu omwe amaphatikiza kulemera kwambiri, matenda ashuga kapena zovuta zina za metabolism ya carbohydrate. Kulandiridwa kwa metformin mu nkhaniyi kumachitika chifukwa cha kuwonetsa mwachindunji, monga hypoglycemic.

Metfogamm 850: malangizo ogwiritsira ntchito, ndemanga

Pambuyo pa chaka chatsopano, ndidapeza (mwa mwayi) ndemanga yokhudza mankhwalawa. Ndinawerenga ndemanga ndi malangizo ndipo ndinasankha kuyesa ndekha ndikugula. Koma ndisanagule, ndidakambirana ndi dokotala ndipo ndidamufunsa momwe Metfogamma 850 imagwirira ntchito pakuchepetsa thupi.

Zinapezeka kuti mankhwalawa amalembedwa kwa anthu onenepa kwambiri ndipo chifukwa cha thanzi sangathe kudzipatsa chakudya. Mwachitsanzo, chilonda cham'mimba, shuga, ndi zina zambiri.Kukonzekera kumakhala ndi zinthu zomwe sizimalola shuga ndi mafuta kuti zimidwe 100%. Amangotulutsidwa m'matumbo.

Mapiritsi oterowo siokwera mtengo - ma ruble 340 okha a 30 zidutswa. Muyenera kumwa mapiritsi awiri patsiku. Ndinkatenga 1 m'mawa, 1 madzulo. Ndikwabwino kuyambitsa maphunzirowa kuyambira kumapeto kwa sabata, chifukwa m'masiku oyambira matumbo amayeretsedwa bwino ndipo simungathe kupita kutali ndi kuchimbudzi.

Sindinapeze vuto lililonse. Thanzi lake ndilabwino, palibe chomwe chimapweteka. Kwa masiku 15, ndimatha kuchepa thupi msanga ndi 5 kg. Za ine - izi ndizotsatira zabwino popanda zakudya ndi masewera.

Koma simungatenge Metphogamm 850 mosalekeza. Ndikofunikira kupatsa thupi kupumula kwa mwezi osachepera. Kwa ine ndekha, ndinapeza mapiritsi abwino kwambiri azakudya. Ndiwotsika mtengo, zikuwonekeratu momwe amagwirira ntchito ndipo amathandizira. Chifukwa chake tsopano ndimangogula mankhwalawa.