Malangizo a Insugen-R (Nthawi zonse)

Tsambali limapereka mndandanda wazonse za Insugen-R analogi (Wokhazikika) mwa kapangidwe kake ndi chisonyezo chogwiritsa ntchito. Mndandanda wama analogi otsika mtengo, mutha kuyerekezeranso mitengo muma pharmacies.

• Mndandanda wotsika mtengo kwambiri wa Insugen-R (Wokhazikika):NovoRapid Flexpen
• Mndandanda wotchuka kwambiri wa Insugen-R (Wokhazikika):Rinsulin P
• Gulu la ATX: Insulin (munthu)
• Zosakaniza / yogwira: insulin yamunthu
  

Mukamawerengera mtengo wake zotupa zotsika mtengo Insugen-R (Wokhazikika) mtengo wocheperako womwe umapezeka mumndandanda wamapulogalamu omwe amaperekedwa ndi ma pharmacies adaganiziridwa

Popeza mndandanda wamankhwala osokoneza bongo kutengera manambala a mankhwala omwe apemphedwa kwambiri

Analogs popanga ndi chisonyezo chogwiritsidwa ntchito

Mndandanda womwe uli pamwambapa wa analogies ya mankhwala, omwe akuwonetsa m'malo Insugen-R (Wokhazikika), ndizabwino kwambiri chifukwa zimakhala ndi zinthu zomwe zimagwirizana ndipo zimagwirana molingana ndi chisonyezo chogwiritsidwa ntchito

Analogs mwa chisonyezo ndi njira yogwiritsira ntchito

Kuphatikizika kosiyanasiyana, kungagwirizane mukuwonetsa komanso momwe mungagwiritsire ntchito

Kodi mungapeze bwanji analogue yotsika mtengo ya mankhwala okwera mtengo?

Kuti mupeze chiwonetsero chotsika mtengo cha mankhwala, chofananira kapena chofanana, choyambirira timalimbikitsa kulabadira kapangidwe kake, zomwe ndi zinthu zomwezo zomwe zikugwiritsidwa ntchito ndikuwonetsa. Zomwe zimagwiritsidwanso mosiyanasiyana ndi mankhwalawa zimawonetsa kuti mankhwalawo ndi ofanana ndi mankhwalawo, monga mankhwala ena kapena mitundu ina. Komabe, musaiwale za zovuta zomwe zimagwiritsidwa ntchito ndi mankhwala ofanana, omwe angakhudze chitetezo ndi kugwiranso ntchito. Musaiwale za malangizo a madotolo, kudzipereka nokha kungawononge thanzi lanu, chifukwa chake onani dokotala wanu musanagwiritse ntchito mankhwala.

Mtengo wa Insugen-R (Wokhazikika)

Pamasamba omwe ali pansipa mutha kupeza mitengo ya Insugen-R (Nthawi zonse) ndikupeza zamankhwala omwe ali pafupi ndi mankhwala

• Mtengo wa Insugen-R (Wokhazikika) ku Russia
• Mtengo wa Insugen-R (Wokhazikika) ku Ukraine
• Mtengo wa Insugen-R (Wokhazikika) ku Kazakhstan

Malangizo a Insugen-R (Nthawi zonse) ogwiritsira ntchito

mankhwala

dyucha recovina: insulin (munthu),

1 ml rozchinu kubwezera anthu a insulin (DNA recombinant) - 40 MO kapena 100 MO.

mawu owonjezera: metacresol, glitserin, 10% rosin acid ndi hydrochloric acid, kapena 10% rosin sodium hydroxide, madzi a inoculation.

Sposib zastosuvannya kuti dozi

Mlingo wa mankhwalawa umaperekedwa kwa wodwala wa dermal payekha pa dermal maalum vipad pamayeso a shuga. Kufunika kwa jakisoni mankhwala kumachokera ku 0,5 mpaka 1 MO / kg / patsiku chifukwa chogwiritsa ntchito wodwalayo ndi glucose glucose.

Іnsugen- (Wokhazikika) kulowa p_dshkіrno mu mafuta kl_tikin wamimba, phewa pa stegna. Uthengawu ndi wofuna kuteteza mkati mwa zigawo za anatomical ngati pali njira yatsopano yosinthira, kuti tisunge chitukuko cha lipodystrophy.

Zoyambitsidwa mu minofu yamafuta am'mimba yam'mimba spry є shvidkі chogwira mankhwalawa m'zigawo ndikuyambitsa komaliza.

Sizotheka kupereka mankhwalawa mkati.

Mankhwalawa amaperekedwa kamodzi kapena kawiri dob.

Mankhwala kutumizidwa 30 hv pamaso іdi, bagato uglevodov.

Insulin yotentha, yomwe imayambitsidwa, ili ndi mlandu wa butyd 18 ° С mpaka 25 ° С.

Asanayambe mankhwala: Atatembenuka, kenaka adatha maphunziro a syringe, insulin, kugwiritsa ntchito botolo: 40 MO / ml kapena 100 MO / ml. Ma syringes a Vicoristovuvati sofunikira kwenikweni kuti athe kumaliza maphunziro, omwe amatha kuganizira kwambiri botolo lopatsidwa.

1. nembanemba wa humic samasamba ndi utoto wa thonje, wothira mowa wa mankhwala.

2. Botolo lotumphuka, kuti mutha kuyanjananso, kuti mutha kuwona komanso osabwezera nyumba yachitatu. M'mbuyomu, mankhwalawa ndi osavomerezeka.

3. Lowani mu syringe nthawi zambiri, mlingo ndi wofanana, mlingo uyenera kutumikiridwa.

4. Tengani syringe mu botolo ndi insulini.

5. Botolo la skupity ndikudzaza syringe ndi insulin yofunika.

Lowaninso, ngati babu silili mu syringe yochulukirapo, lembaninso mlingo.

6. Yambitsani inіsіlіn pіdshkіrno.

Yak kukhazikitsa Denmark іnsulіn:

• Lowani pini ndi zala ziwiri, lowani pini ndi pini ndikulowa mu syringe,

• Gwiritsani ntchito cholinga kwa masekondi 6 ndi kutalika kwa masekondi 6 ndikuyanjanitsa, zomwe zingayambitse mawu oyamba, kupambana

• Monga lamulo, pamtunda wa shkiri, pankapezeka chitetezo, kotero kuti iwo adaphwanya golk, kufinya siketi yonse ya shkiri ndi swab thonje.

Poyambitsa Insugenu-Reg (wokhazikika), makatoni amafunika kukhala ndi cholembera cha vikoristovuvati INSUPen yokhala ndi buku la malangizo lazomwe zingakhalepo ndi cholembera. Osadzazanso katoni. INSUPen imasankhidwa kokha ma Vikings omaliza. Moyenera suvorotrimatsya іnstrucіі virobnika shodo vikoristannya syringe zolembera INSUPen.

Zochita

Pobichn_ efekti, pov'yazanі z vlivom pamtengo wogulitsa chakudya: Hypoglycemia (zochulukirapo, zophimba zazikulu za shkirnih, mantha, kunjenjemera, nkhawa, nevichna vtea ndi kufooka, kusokonezeka kwa ulemu, chisokonezo, kunyalanyaza, bata). Kutembenuka gіpoglіkemіya kumatha kubweretsa theka kuwala kwa khothi.

Zotsatira zoyipa: pafupipafupi - kropiv'yanka, shkіrniy visip, uzhe r_dko - anaphylactic zochita.

Zokhudza: Zotsatira za mziwopsezo (redundancy, scging, overrating the lead), muyenera kusiya kuyankhula panthawi yogulitsa, infrequently - subdystrophy.

Інші: pa machira a zamankhwala amadzichitira chipongwe, zomwe zimapangitsa kuti zikhale zowonongeka.

Makamaka zimachitikira odwala omwe amafunika kuwumitsa mankhwala Insugen- (Wokhazikika), є, makamaka, amakhala ndi mankhwala osokoneza bongo komanso kupatsidwa mphamvu ndi insulin.

Kwambiri

Zizindikiro: Hypoglycemia (zochulukirapo, zophimba zazikulu za shkirnih, mantha, kunjenjemera, nkhawa, nevichna vtea ndi kufooka, kusokonezeka kwa ulemu, chisokonezo, kunyalanyaza, bata).

Likuvannya: mutha kupepuka gіpoогlіkemіy patsєnt ndikuyika nokha, mutenga pakatikati pa glucose, zukor kapena bagati wokhala ndi zakudya zamatumbo a gruel (pats tikulimbikitsidwa kuti nthawi zonse azinyamula zucor, malt, tiyi, zipatso). Mukugwa kwambiri, wodwalayo akadutsa wodwala, lowetsani 40% ya dextrose, glucagon (0.5-1 mg) mkati. Ndikupangira kuti ulandire uthengawu kwa zipani za Chipani kuti uvomereze ngongoleyo, yomwe ndi Bugatu pogwiritsa ntchito mafuta, kuti uzikumbukira kukonzanso kwa uthengawo.

Zastosuvannya munthawi ya vіtnostі і chaka

Ndilibe ukwati wapadera wogwira insulin panthawi yomwe muli ndi matenda ashuga, zidutswa za insulin za anthu sizimalowa placenta. Munthawi ya ntchito yayikulu kwambiri pachaka komanso kukulitsa mawu onse ofunikira, kudekha kwa msasawo ndikofunikira kuti muwoneke mtima, komanso kuwongolera kuchuluka kwa shuga m'magazi. Kufunika kwa insulin, monga lamulo, kumatsitsidwa mu trimester yoyamba ndikuwonjezeka pang'onopang'ono mu zina ndi zitatu zachitatu za vaginosti. Kwa ola limodzi, ndizitha kuchita popanda kusokoneza. Ponseponse, titha kuwachepetsa mwachangu. Mukamalemba za zofunikira zachuma, sinthani mpaka mutagulika, mtundu wa buv kuti utembenuke. Mu nthawi ya mkaka wa m`mawere (thoracic vigodovuvannya) Іnsugen- (Wokhazikika) akhoza zasosovuvatsya popanda obmezhen (oyambitsa іnsulіnu mayi, scho chaka є, sangathe kulingalira kuwopsa kwa ana). Mapuloteni, mutha kukhala ndi kufunika kwa mlingo woyenera wa mankhwalawa.

Insulin ilibe mkaka wa m'mawere.

Mlingo wa mankhwalawa umaperekedwa kwa wodwalayo payekhapayekha pakhungu lomwe limayambitsa khungu kuti athe kukhazikika kwa shuga komanso kuuma kwa zosafunikira za ogula.

Zina zastosuvannya

Mapulogalamu okhala ndi insulin amatha kukhala ndi kovpachok ya pulasitiki yaying'ono, yomwe muyenera kudziwa musanalowe mu insulin. Wodwalayo walangizidwa kuti akhale ndi njoka, koma kapchak adzakhala wosachotsedwa ntchito, vin ali ndi vuto posatembenuza botolo kukhala mankhwala.

Pamakhalidwe azithandizo, kuyenera kosalekeza kwa glucose koyenera ndikofunikira.

Palibe vuto kusiya, koma mankhwala osokoneza bongo owonjezereka, makamaka matenda a shuga a shuga, angayambitse matenda oopsa a shuga komanso matenda ashuga a ketoacidosis. Mokweza, zizindikiro zoyambirira za hyperglichia zimawonetsedwa ndi kutalika kwa decilcohodin mu masiku. Amawonetsedwa ndiuma mkamwa, kupopera, nthawi zambiri sechovypuskannya, nseru, kupindika, kutsekeka, kupunduka komanso kuwuma kwa shkiri, kusowa kwa chilankhulo, kununkhira kwa acetone akamwalira. Hyperglycemia yokhala ndi mtundu wa matenda a shuga I amellicus angayambitse kukula kwa msasa wopulumutsa moyo - matenda ashuga ketoacidosis. Kugwidwa kwa Suputny, makamaka kosapweteka komanso kukhala bwino, chifukwa chogwiritsa ntchito kwambiri ngati galu wotentha, kuti athe kufunikira wodwala insulin. Koretsiya dozi іnsulіnu mogozhe butchi ayenera kukhala, Komanso, matenda zbіlshuє kupikisana zolimbitsa thupi abo zmіnyuє mode grubuvannya. Kuyambukira mtundu umodzi wa insulini kupita ku yomaliza kumapangitsa kuti wodwala azingokhala.

Mankhwala sangafike kulowetsedwa rosinov.

Pakufunika kupezerapo mwayi mchitidwewu, monga wodwala akukhalabe wowopsa, makamaka kubwezera shuga ndi chakudya.

Pakufunika kulandira upangiri kuchokera kwa anthu nthawi ya matenda, kupsinjika kwa m'maganizo, kulandira chithokomiro mosalamulirika, komanso nthawi zambiri ola limodzi la opareshoni.

Kufunika kwalandilidwe kungasinthidwe panthawi yamtundu wa nirok, koma kuti amvetsetse ntchito zochepa, magwiridwe a mipando ya nadnirkovo, kapena hypophysis.

Vz зmodiya ndi іnshimi lіkarskimi matimu omwe іnshі amawona

Hypoglycemic ikuwonetsa mphamvu zama MAO, osagwiritsa ntchito beta-adrenergic yoletsa, sulfanilamides, anabolic steroids, tetracycline, klofibrat, cyclophosphamide, phenol,

Hypoglycemic effect imachepetsa njira zolerera za pakamwa, glucocorticoid, mahomoni a chithokomiro, diuretics ya thiazine, heparin, kukonzekera kwa lifiyamu, mankhwala antidepressants.

Mu malo oyamba, malo osungirako ndalama ndi malipiro atha kufooka, motero mphamvuyo imalimbikitsidwa.

Ethanol, kupha tizilombo toyambitsa matenda kwapadera kumachepetsa ntchito ya insulin.

Atsogoleri azachipatala

Mankhwala Іnsugen- (Wokhazikika) - chomwe chimayambitsa kufupikitsa kwakanthawi kwa DNA ya anthu.

Naybіlsh yofunika dієu іnsulіnu ulation malamulo kagayidwe kachakudya. Ndikudziwa kuti nditha kutenga glucose m'magazi, kulimbikitsa kukoka kwa glucose pogwiritsa ntchito zotumphukira (makamaka mafupa aminyewa ndi minyewa ya adipose), komanso kugwiritsa ntchito glucose kukoka kwa glucose (gluconeogenesis).

Odwala omwe ali ndi matenda a shuga a m'magazi, mankhwalawa amachepetsa njira zonse, amapaka metabolism, amawonjezera kuthamanga, komanso azizungulira matenda ashuga.

cob wa dії - kutalika kwa pivodini,

pazabwino: pambuyo 2-5 wazaka,

triviality dії: zaka 4 mpaka 6.

Pharmacokinetics. Insulin m'magazi a nthawi ya amayi kumapeto kwa Disembala decilka hvilin. Njira yodzaza ofesi ya zigawozi ndi: kukonza mawu oyamba ndi oyambitsa.

Umovi zberigannya

Zberigati pamalo osavomerezeka ndi ana, pakapangidwe koyambirira, kutentha kwa 2 ° C mpaka 8 ° C, kuti asazizidwe.

Sizingatheke kunena kuti kukonzekera kutha kwa zabwino zomwe zikuwonetsedwa pamaphukusi. Sizingatheke kupaka mankhwalawa; monga lamulo, ngati simupeza botolo la vial, osaphimba;

Kulongedza. 10 ml pa botolo. Botolo 1 pa paketi iliyonse.

1 ml ya inoculum ya vial ndi mphamvu ya 40 MO;

3 ml pa cartridge. Makatiriji asanu pachimake, chithunthu chimodzi pa paketi limodzi.

1 ml ya maziko a inoculation a cartridge ndi 100 MO ya anthu (DNA recombinant).