Mankhwala atsopano pochiza matenda a shuga a 2

Aliyense amadziwa kuti matenda ashuga amagawidwa m'mitundu iwiri. Mtundu wa shuga wodalira insulin 1 amadziwika ndi zovuta m'matumbo, omwe amasiya kutulutsa insulin kapena samatulutsa zokwanira. Pankhaniyi, mankhwala obwezeretsera omwe ali ndi mankhwala ngati a insulin amagwiritsidwa ntchito. Mtundu wachiwiri wa matenda ashuga, insulini imapangidwa mokwanira, koma ma cell a cell sangathe kuyamwa. Pankhaniyi, mankhwala a shuga ayenera kusintha shuga m'magazi ndikulimbikitsa kugwiritsidwa ntchito kwa shuga.

Mankhwala othandizira odwala omwe samadalira insulin amadziwika chifukwa cha wodwala, msinkhu wake, kulemera kwake komanso kupezeka kwa matenda olimba. Ndizachidziwikire kuti mankhwalawa omwe amaperekedwa pochizira matenda amishuga a 2 sayenera kwenikweni kwa odwala matenda ashuga omwe insulin yake siyipangidwa. Chifukwa chake, ndi akatswiri okhawo omwe angasankhe chida choyenera ndikudziwa njira zamankhwala zoyenera.

Izi zingathandize kuchepetsa kuchepa kwa matendawa komanso kupewa zovuta zazikulu. Ndi mankhwala ati a shuga omwe ali bwino komanso othandiza? Ndikovuta kupereka yankho losatsimikizika pafunso ili, chifukwa mankhwala omwe ali ndi vuto labwino kwa wodwala m'modzi amatsutsana kwathunthu ndi linzake. Chifukwa chake, tiyesetsa kupereka chidule cha mankhwala otchuka a shuga ndikuyamba ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda a shuga a 2.

Lemberani mankhwala a shuga atatu

Odwala omwe ali ndi matenda amtundu wa 2 amatha kupita popanda mapiritsi ochepetsa shuga kwa nthawi yayitali ndikukhalabe ndi shuga yamagazi pokhapokha ngati akutsatira zakudya zamagulu ochepa komanso kuchita masewera olimbitsa thupi okwanira. Koma zosungirako zamkati za thupi sizikhala zopanda malire ndipo zikafooka, odwala ayenera kusintha kuti amwe mankhwala.

Mankhwala ochiza matenda amisala 2 a shuga amadziwika kuti zakudya sizipereka zotsatira ndipo shuga wamagazi akupitilira kuchuluka kwa miyezi itatu. Koma nthawi zina, ngakhale kumwa mankhwala akumwa sikothandiza. Kenako wodwalayo amasinthira jakisoni wa insulin.

Mndandanda wamankhwala a matenda a shuga a 2 ndiwambiri kwambiri, onse amatha kugawidwa m'magulu akulu akulu:

Chithunzi: mankhwala osokoneza bongo a matenda a shuga 2

  1. Ma siriagog ndi mankhwala omwe amachititsa kuti insulin itulutsidwe. Nawonso, amagawika m'magulu awiri: masoka a sulfonylurea (Diabeteson, Glurenorm) ndi meglitinides (Novonorm).
  2. Sensitizer - mankhwala omwe amachititsa chidwi cha minyewa pakutsata insulin. Amagawidwanso m'magulu awiri: Biguanides (Metformin, Siofor) ndi thiazolidinediones (Avandia, Aktos).
  3. Alfa glucosidase zoletsa. Mankhwala omwe ali mgululi ali ndi udindo wokhazikitsa kuyamwa kwa matumbo m'matumbo ndikuchotsedwa kwawo mthupi (Acarbose).
  4. Mankhwala a mtundu wachiwiri wa matenda am'badwo watsopano ndi ma insretin. Izi zikuphatikizapo Januvia, Exenatide, Lyraglutide.

Tikhazikike pagulu lililonse la mankhwala:

Sulfonylureas

Chithunzi: Zochokera ku Sulfonylurea

Kukonzekera kwa gululi lakhala likugwiritsidwa ntchito pochita zachipatala kwa zaka zoposa 50 ndipo ndi koyenera. Amakhala ndi hypoglycemic chifukwa cha mwachindunji maselo a beta omwe amapanga insulin mu kapamba.

Zimachitika zomwe zimachitika m'magawo am'magazi zimapereka kutulutsidwa kwa insulin ndikutulutsa kwake m'magazi. Mankhwala osokoneza bongo omwe ali mgululi amalimbikitsa chidwi cha maselo ku glucose, amateteza impso kuwonongeka, komanso amachepetsa chiopsezo cha zovuta zam'mitsempha.

Nthawi yomweyo, kukonzekera kwa sulfonylurea kumachepetsa maselo a pancreatic, kumayambitsa zovuta zoyipa, kulemera, kudzimbidwa, ndikuwonjezera chiopsezo cha machitidwe a hypoglycemic. Samagwiritsidwe ntchito mwa odwala omwe ali ndi matenda a shuga a pancreatic, ana, amayi apakati komanso oyamwitsa.

Pakumwa mankhwala, wodwala amayenera kutsatira zakudya zamafuta ochepa ndikumangiriza kudya mapiritsi ake. Oimira otchuka a gululi:

Glycvidone - mankhwalawa ali ndi zotsutsana zochepa, motero, amapatsidwa mankhwala omwe odwala samapereka zotsatira zomwe akufunazo komanso okalamba. Zochitika zochepa zoyipa (kuyabwa pakhungu, chizungulire) zimasinthidwanso. Mankhwalawa akhoza kuikidwa ngakhale ndi kulephera kwa aimpso, chifukwa impso sizichita nawo gawo lanyama kuchokera m'thupi.

  • Maninil - amadziwika kuti ndi mankhwala amphamvu kwambiri a kapamba mu shuga. Amapangidwa ngati mapiritsi omwe amakhala ndi mitundu yosiyanasiyana ya yogwira (1.75, 3.5 ndi 5 mg) ndipo amagwiritsidwa ntchito pamagulu onse a shuga. Kutha kuchepetsa kuchuluka kwa shuga kwa nthawi yayitali (kuyambira maola 10 mpaka 24).
  • Diabetes mankhwalawa amagwira ntchito makamaka mu gawo la 1 la kupanga insulin. Kuphatikiza apo amapereka chitetezo chodalirika cha mitsempha yamagazi ku zowopsa za glucose.
  • Amaryl ndiye mankhwala abwino kwambiri a matenda ashuga amtundu wa 2. Mosiyana ndi mankhwala ena omwe amachepetsa shuga, sizimapangitsa kuti muchepetse kunenepa komanso zimakhala ndi zotsatirapo zoipa pamtima ndi m'mitsempha yamagazi. Ubwino wa mankhwalawa ndikuti amachotsa insulin pang'ono m'magazi, zomwe zimapewe kukula kwa hypoglycemia.
  • Mtengo wapakati wa kukonzekera kwa sulfonylurea ndi wochokera ku ma ruble 170 mpaka 300.

    Meglitinides

    Mfundo zoyenera kuchita ndi gulu ili la mankhwala ndikulimbikitsa kupanga kwa insulin ndi kapamba. Kugwiritsa ntchito bwino kwamankhwala kumadalira kuchuluka kwa glucose m'magazi. Mukakhala ndi shuga, insulin yambiri imapangidwa.

    Oimira meglitinides ndi kukonzekera kwa Novonorm ndi Starlix. Ndiwo m'badwo watsopano wamankhwala, amadziwika ndi zochita zazifupi. Mapiritsi ayenera kumwedwa kwa mphindi zochepa asanadye. Mankhwalawa amawerengedwa monga gawo la zovuta za matenda a shuga. Amatha kuyambitsa mavuto monga kupweteka kwam'mimba, kutsegula m'mimba, matupi awo sagwirizana ndi hypoglycemic.

    1. Novonorm - dokotala amasankha mlingo wa mankhwalawo payekha. Piritsi imatengedwa katatu patsiku, musanadye. Novonorm amachepetsa shuga m'magazi bwino, kotero ngozi yotsika ndi shuga m'magazi ndi yochepa. Mtengo wa mankhwalawa umachokera ku ma ruble a 180.
    2. Starlix - pazipita mphamvu ya mankhwala zimachitika mphindi 60 pambuyo makonzedwe ndipo kumakhala kwa 6-8 maola. Mankhwalawa ndi osiyana chifukwa samapangitsa kuchulukitsa, sakhala ndi vuto pa impso ndi chiwindi. Mlingo umasankhidwa payekha.

    Mankhwalawa a matenda a shuga a 2 amalepheretsa shuga kutuluka kwa chiwindi ndipo amathandizira kuti mayamwidwe abwino komanso kusuntha kwa glucose m'maselo ndi minyewa yamthupi. Mankhwala a gululi sangagwiritsidwe ntchito ngati 2 odwala matenda ashuga omwe ali ndi vuto la mtima kapena la impso.

    Kuchita kwa Biguanides kumatenga maola 6 mpaka 16, amachepetsa kuyamwa kwa shuga ndi mafuta kuchokera m'matumbo ndipo samayambitsa kugwa kwamphamvu m'magazi. Amatha kuyambitsa kusintha kwamakomedwe, nseru, kutsekula m'mimba. Mankhwala otsatirawa ndi a gulu la Biguanides:

    1. Siofor. Mankhwalawa nthawi zambiri amawalembera odwala omwe ali ndi kunenepa kwambiri, chifukwa kumwa mapiritsi kumathandizira kuchepetsa thupi. Mlingo wapamwamba kwambiri wa mapiritsi tsiku lililonse ndi 3 g, imagawidwa pawiri. Mulingo woyenera wa mankhwala amasankhidwa ndi adokotala.
    2. Metformin. Mankhwala amachepetsa kuyamwa kwa glucose m'matumbo ndikuti amathandizira kugwiritsidwa ntchito kwake mu zotumphukira.Mapiritsi amaloledwa bwino ndi odwala, amatha kuikidwa limodzi ndi insulin ndi kunenepa kwambiri. Dokotala amasankha mlingo wa mankhwalawo payekha. Chotsutsana pa kugwiritsa ntchito Metformin ndimtundu wa ketoacidosis, matenda akulu a impso, komanso nthawi yokonzanso atachitidwa opaleshoni.

    Mtengo wamba wa mankhwalawa umachokera ku ma ruble 110 mpaka 260.

    Thimang

    Mankhwala osokoneza bongo a shuga m'gululi, komanso ma biguanides, amathandizira kuyamwa kwa glucose ndi minofu ya thupi ndikuchepetsa kumasulidwa kwa shuga ku chiwindi. Koma mosiyana ndi gulu lakale, ali ndi mtengo wokwera kwambiri ndi mndandanda wazotsatira zoyipa. Izi ndi kulemera kwakukulu, kusokonekera kwa mafupa, chikanga, kutupa, kusokoneza ntchito za mtima ndi chiwindi.

    1. Aktos - chida ichi chitha kugwiritsidwa ntchito ngati mankhwala amodzi pochiza matenda a shuga a 2. Kuchita kwa mapiritsiwo ndi cholinga chowonjezera kukhudzika kwa minyewa kupita ku insulin, kuchepetsa kapangidwe ka shuga m'chiwindi, kumachepetsa chiopsezo cha kuwonongeka kwa mtima. Mwa zovuta za mankhwalawa, kuwonjezeka kwa thupi panthawi ya makonzedwe kumadziwika. Mtengo wamankhwala amachokera ku ruble 3000.
    2. Avandia - othandizira amphamvu a hypoglycemic omwe zochita zake zimayang'ana kukonza njira zama metabolic, kutsitsa shuga m'magazi ndikuwonjezera chidwi cha minofu ku insulin. Mapiritsi amatha kugwiritsidwa ntchito ngati matenda a shuga a 2 monga monotherapy kapena kuphatikiza ndi ena othandizira a hypoglycemic. Mankhwalawa sayenera kuperekedwa chifukwa cha matenda a impso, pakakhala pakati, paubwana komanso hypersensitivity kwa yogwira mankhwala. Mwa zina zoyipa zomwe zimachitika, mawonekedwe a edema ndi kuphwanya ntchito za mtima ndi zida zamagayidwe amadziwika. Mtengo wapakati wamankhwala amachokera ku ruble 600.

    Alpha Glucosidase Inhibitors

    Mankhwala ofananawo a shuga amalepheretsa kupanga enzyme yapadera yamatumbo yomwe imasungunula zovuta zamimba. Chifukwa cha izi, kuchuluka kwa mayamwidwe a polysaccharides kumachepetsedwa kwambiri. Awa ndi mankhwala amakono ochepetsa shuga, omwe kwenikweni alibe zotsatira zoyipa, samayambitsa matenda am'mimba komanso kupweteka kwam'mimba.

    Mapiritsi ayenera kumwedwa ndi chakudya choyamba, amachepetsa shuga komanso samakhudza maselo a pancreatic. Kukonzekera kwa nkhondoyi kumatha kugwiritsidwa ntchito limodzi ndi othandizira ena a hypoglycemic ndi insulin, koma chiwopsezo cha kuwonetsa kwa hypoglycemic chikuwonjezeka. Oyimira bwino a gululi ndi Glucobay ndi Miglitol.

    • Glucobai (Acarbose) - mankhwalawa amalimbikitsidwa kuti atengedwe ngati shuga atakwera kwambiri atangodya. Mankhwalawa amalekeredwa bwino, samayambitsa kuwonjezeka kwa thupi. Mapiritsi amalembedwa ngati mankhwala othandizira kuti athandize pakudya chamafuta ochepa. Mlingo umasankhidwa payekhapayekha, tsiku lililonse mumatha kumwa 300 mg ya mankhwalawa, ndikugawa Mlingo uwu mu 3 waukulu.
    • Miglitol - Mankhwala amapatsidwa odwala omwe ali ndi digiri ya 2 matenda a shuga, ngati zakudya ndi zolimbitsa thupi sizingachitike. Mapiritsi akulimbikitsidwa kuti atenge pamimba yopanda kanthu. Contraindication chithandizo ndi Miglitol ndi mimba, ubwana, matenda a m'matumbo, kupezeka kwa hernias yayikulu. Nthawi zina, wothandizirana ndi hypoglycemic amakwiya. Mtengo wa mankhwala omwe ali mgululi amasiyana kuchokera 300 mpaka 400 ma ruble.

    M'zaka zaposachedwa, m'badwo watsopano wa mankhwala wawoneka, omwe amatchedwa dipeptidyl peptidase inhibitors, omwe kuchitapo kwawo ndikukuwonjezera kupanga kwa insulini kutengera kukhudzana kwa glucose. Mu thupi lathanzi, zopitirira 70% za insulini zimapangidwa moyenera mothandizidwa ndi mahomoni a insretin.

    Zinthu izi zimayambitsa zochitika monga kutulutsidwa kwa shuga ku chiwindi ndikupanga insulin ndi maselo a beta. Mankhwala atsopano amagwiritsidwa ntchito ngati njira yokhayokha kapena amaphatikizidwa ndi zovuta kuchipatala.Amatsitsa bwino kuchuluka kwa glucose ndikutulutsa masitolo a insretin kuti athane ndi shuga.

    Imwani mapiritsi mukamadya kapena mukatha kudya. Amalekeredwa bwino ndipo samathandizira kulemera. Gulu la ndalama izi limaphatikizapo Januvia, Galvus, Saksagliptin.

    Januvia - mankhwalawa amapangidwa mwa mapiritsi okhala ndi mankhwala okhala ndi mphamvu ya 25, 50 ndi 100 mg. Mankhwalawa amayenera kumwa kamodzi kokha patsiku. Januvia samayambitsa kulemera, amathandizira glycemia bwino pamimba yopanda kanthu komanso pakudya. Kugwiritsa ntchito mankhwalawa kumachepetsa kukula kwa matenda ashuga komanso kumachepetsa chiopsezo cha zovuta zotheka.

  • Galvus - yogwira mankhwala - vildagliptin, imalimbikitsa ntchito ya kapamba. Pambuyo pa kayendetsedwe kake, katulutsidwe ka ma polypeptides ndi chidwi cha maselo a beta kumakulitsidwa, ndikupanga insulin. Mankhwalawa amagwiritsidwa ntchito ngati monoterium, kuthandizira zakudya ndi zolimbitsa thupi. Kapena kutumikiridwa pamodzi ndi othandizira ena a hypoglycemic.
  • Mtengo wapakati wa Januvia ndi ma ruble 1,500, Galvus - 800 rubles.

    Odwala ambiri omwe ali ndi matenda a shuga a 2 amawopa kusinthira insulin. Komabe, ngati chithandizo chamankhwala ena ochepetsa shuga sichikupatsani chifukwa shuga amakwera pang'onopang'ono mpaka 9 mmol / l mukatha kudya mkati mwa sabata, muyenera kuganizira za kugwiritsa ntchito mankhwala a insulin.

    Ndi zizindikiro zotere, palibe mankhwala ena a hypoglycemic omwe amatha kukhazikika. Kunyalanyaza malangizo azachipatala kumabweretsa zovuta zowopsa, chifukwa chifukwa chokhala ndi shuga yokhazikika chiwopsezo chokhala ndi kulephera kwa impso, zovuta kwambiri, kutayika kwa malingaliro ndi zinthu zina zomwe zimayambitsa kulumala kumakulitsidwa kwambiri.

    Mankhwala ena a shuga

    Chithunzi: Matenda Osiyanasiyana a shuga - Diabenot

    Chimodzi mwazomwe mungagwiritse ntchito ndi mankhwala a matenda a shuga a Diabenot. Ichi ndichopanga cha magawo awiri opangidwa motengera zomera zotetezeka. Mankhwalawa adapangidwa ndi akatswiri azamankhwala aku Germany ndipo amangotuluka kumene pamsika waku Russia.

    Makapisozi a Diabenot amathandizira kugwira ntchito kwa maselo a pancreatic beta, kusintha njira zama metabolic, kuyeretsa magazi ndi magazi, kuchepetsa shuga, kupewa kukula kwa zovuta ndi chitetezo chokwanira.

    Kumwa mankhwalawa kungathandize kupanga insulini, kupewa glycemia ndikubwezeretsa ntchito za chiwindi ndi kapamba. Mankhwalawa alibe zotsutsana ndi zoyipa zilizonse. Tengani makapisozi kawiri patsiku (m'mawa ndi madzulo). Mankhwalawa akugulitsidwa mpaka pano pa tsamba lovomerezeka la wopanga. Werengani zambiri ndi malangizo ogwiritsa ntchito ndi ndemanga za makapisozi a Diabenot apa.

    Mtundu wa mankhwala a matenda ashuga 1

    Mankhwala omwe amagwiritsidwa ntchito pochiza matenda amtundu wa shuga amatha kugawidwa m'magulu awiri: awa ndi ofunikira a insulin ndi mankhwala ena omwe amathandizidwa kuti athetse matenda omwe amakhalanso amodzi.

    Ndizololedwa kulandira insulin, kutengera kutalika kwa zochita, m'mitundu ingapo:

    Insulin yochepa - imakhala nthawi yayitali ndipo imakhala ndi chodwala pakatha mphindi 15 kuchokera pakulowetsedwa.

  • Insulini yapakatikati - imayendetsedwa pafupifupi maola 2 mutatha kukhazikitsa.
  • Insulin yayitali - imayamba kugwira ntchito patatha maola 4-6 jakisoni.
  • Kusankhidwa kwa mankhwala oyenera, kusankha kwa mankhwala ndi njira zochizira kumachitika ndi endocrinologist. Mankhwala a insulini amachitika mwa kubaya kapena kupaka insulini, yomwe imaperekera Mlingo wambiri wa mankhwala m'thupi.

    Mankhwala ochokera ku gulu lachiwiri lomwe amagwiritsidwa ntchito pochiza matenda amtundu wa 1 amaphatikizapo:

    Chithunzi: ACE zoletsa

    ACE inhibitors - kuchitapo kwawo ndikofunikira kuti magazi akhale athanzi komanso kupewa mavuto abwera chifukwa cha mankhwala ena a impso.

  • Mankhwala omwe machitidwe awo cholinga chake ndi kuthana ndi matenda am'mimba omwe amayambitsidwa ndi matenda a shuga 1. Kusankhidwa kwa mankhwalawa kumatengera mtundu wamavuto ndi zizindikiro zamatenda. Dokotala wothandizila amakupatsani mankhwala.
  • Ndi chizolowezi cha matenda amtima, mankhwala amalembedwa omwe amayimitsa zizindikiro za matendawa ndikuthandizira ntchito ya mtima ndi mitsempha yamagazi.
  • Matenda a shuga nthawi zambiri amakhala ndi matendawa. Pofuna kuthana ndi mawonetseredwe awa, mankhwala amasankhidwa omwe amachepetsa cholesterol yamagazi.
  • Zizindikiro za zotumphukira zikaonekera, mankhwalawa omwe ali ndi mankhwala ochita kupanga amagwiritsidwa ntchito.
  • Chithandizo chovuta kwambiri cha matenda a shuga amtundu woyamba 1 ndicholinga chothandiza wodwalayo komanso kupewa mavuto. Matenda a shuga masiku ano amaonedwa kuti ndi matenda osachiritsika, motero pangafunike kumwa mankhwala ochepetsa shuga kapena kulandira chithandizo cha insulini m'moyo wonse.

    Ndemanga za Chithandizo

    Unikani Na. 1

    Chaka chatha ndidapezeka ndi shuga wambiri. Dokotalayo adamulembera zakudya zowonjezera ndikuwonjezera zolimbitsa thupi. Koma ntchito yanga ndiyakuti sizikhala zotheka nthawi zonse kudya zakudya panthawi. Kuphatikiza apo, kulibe nthawi yoti makalasi azilimbitsa thupi.

    Koma ndidayesetsabe kutsatira malangizo azachipatala ndipo ndimayang'anira kuchuluka kwa shuga m'magazi. Kwa nthawi yayitali zinali zotheka kuti zizikhala zovomerezeka, koma posachedwa kuchuluka kwa shuga kwakhala kokwezeka kwambiri ndipo sizinatheke kuti abweretse.

    Chifukwa chake, adotolo adatinso mankhwala ochepetsa shuga a Miglitol. Tsopano ndimamwa mapiritsi tsiku lililonse, ndipo shuga wanga wayamba kuchepa, ndipo thanzi langa layamba bwino.

    Dina, St. Petersburg

    Ndili ndi matenda ashuga omwe ndimakumana ndi zovuta, nditakhala pa insulin. Nthawi zina pamakhala zovuta ndi kugula kwa mankhwalawo, ndipo yonseyo mutha kukhala ndi moyo. Ndili ndi matenda ashuga amtundu wa 2, poyamba adapereka mankhwala ochepetsa shuga, zakudya, masewera olimbitsa thupi. Chithandizo choterechi chimakhala ndi zotsatira zake, koma pamapeto pake, regimenyi idasiya kugwira ntchito ndipo ndidasinthira jakisoni wa insulin.

    Ndimayesedwa chaka chilichonse, ndimayang'ana m'maso, chifukwa pamakhala chiopsezo cha kuwonongeka kwa retin, ndimayang'ananso njira zina zodzitetezera.

    Ndikudwala matenda ashuga a 2 mtundu. Tsopano kutenga Acarbose. Mapiritsi amayenera kuledzera ndi zakudya. Amalekeredwa bwino, samatulutsa zotsatira zoyipa, ndipo koposa zonse, mosiyana ndi mankhwala ena ochepetsa shuga, samathandizira kupeza mapaundi owonjezera.

    Ngakhale mankhwalawa amathandizira bwino, inde, kuphatikiza zakudya zamagulu ochepa zopatsa mphamvu ndikuchepetsa kudya zakudya zosavuta zamafuta.

    Gulu la mankhwala

    Ndi chitukuko cha matenda ashuga amtundu 2, odwala samalandira mankhwala mwachangu. Pongoyambira, kudya mokhazikika komanso kuchita masewera olimbitsa thupi mokwanira kuti muziwongolera shuga. Komabe, zochitika ngati izi sizimapereka zabwino nthawi zonse. Ndipo ngati siziwoneka mkati mwa miyezi iwiri, tengani chithandizo chamankhwala.

    Mankhwala onse ochizira matenda a shuga amagawika m'magulu angapo:

    • chinsinsi, chimalimbikitsa kuphatikiza kwa insulini ndi ma cell a beta a kapamba, amagawidwa kukhala sulfonylureas ndi megoitinides,
    • masisitimu, omwe amathandizira kukulitsa chidwi cha maselo amthupi kuti apange insulini, ali ndi magawo awiri - biguanides ndi thiazolidinediones,
    • alpha-glucosidase zoletsa zomwe zimapangitsa kuti pakhale kusweka, mayamwidwe ndi michere yamafuta m'thupi,
    • maretretin, omwe ndi mankhwala obwera kumene omwe ali ndi zotsatira zingapo mthupi.

    Malangizo

    Kumwa mankhwala a matenda a shuga a mtundu wachiwiri ndi cholinga chokwaniritsa zolinga izi:

    Chepetsani minofu insulin.

    Yambitsani ntchito ya insulin synthesis.

    Pewani kuyamwa kwatsopano kwa shuga m'magazi.

    Bweretsani mulingo wa lipid mu thupi kukhala labwinobwino.

    Therapy iyenera kuyamba ndi mankhwala amodzi. M'tsogolomu, kuyambitsidwa kwa mankhwala ena ndikotheka. Ngati zotsatira zomwe mukufuna sizingatheke, dokotala amalimbikitsa wodwala kulandira insulin.

    Magulu akuluakulu a mankhwala osokoneza bongo

    Kumwa mankhwala osokoneza bongo a shuga 2 ndichofunikira kuti mukhale ndi thanzi. Komabe, tisaiwale za kukhala ndi moyo wathanzi komanso kudya zakudya zoyenera. Komabe, sianthu onse omwe amatha kuphatikiza mphamvu ndikudzikakamiza okha kuti akhale moyo watsopano. Chifukwa chake, kukonza madokotala kumafunika nthawi zambiri.

    Kutengera ndi zochizira, odwala matenda a shuga amatha kutumikiridwa mankhwala ochokera m'magulu otsatirawa:

    Mankhwala omwe amachotsa kukana kwa insulin ndi thiazolidinediones ndi biguanides.

    Mankhwala omwe amathandizira kupanga insulin m'thupi ndi ma dongo komanso sulfonylureas.

    Kukonzekera kokhala ndi kuphatikizika ndi ma insretinomimetics.

    Mankhwala omwe amapezeka ndi odwala matenda a shuga:

    Biguanides ndi mankhwala opangidwa ndi metformin (Glucofage, Siofor).

    Zotsatira zamankhwala zimatheka pogwiritsa ntchito njira zotsatirazi:

    Mukakonza glycogen, komanso mapuloteni ndi chakudya, kaphatikizidwe kamatenda amachepa.

    Minofu imayamba kugwiritsidwa ntchito ndi insulin.

    Mu chiwindi, shuga amawonjezera mawonekedwe a glycogen amawonjezeka.

    Shuga amalowa m'magazi ochepa.

    Glucose amalowa m'maselo ndi minyewa yamkati yamkati yambiri.

    Kumayambiriro kwa chithandizo cha mankhwala ndi biguanides, odwala amakumana ndi zovuta kuchokera kugaya chakudya. Komabe, pakatha masiku 14 iyimitsidwa, ndiye muyenera kuyiyang'anira. Ngati izi sizingachitike, ndiye kuti muyenera kulumikizana ndi katswiri yemwe amasintha njira zochizira.

    Zotsatira zoyipa izi ndi monga:

    Maonekedwe a kukoma kwazitsulo mkamwa.

    Sulfonylurea

    Zotumphukira za Sulfonylurea zimatha kumangiriza ku beta receptors mu cell ndikuthandizira kupanga insulin. Mankhwalawa ndi monga: glycidone, glurenorm, glibenclamide.

    Kwa nthawi yoyamba, mankhwalawa amatchulidwa muyezo wotsika kwambiri. Kenako, masiku opitilira 7, amawonjezedwa pang'onopang'ono, ndikubweretsa mtengo womwe mukufuna.

    Zotsatira zoyipa za kutenga mankhwala a sulfonylurea:

    Kutsika kwakuthwa m'magazi a magazi.

    Mawonekedwe otupa m'thupi.

    Kugonjetsedwa kwa dongosolo logaya chakudya.

    Ma Clinides amaphatikizapo kukonzekera kwa Nateglinide ndi Repaglinide. Zotsatira zake ndikuwonjezera kupanga kwa insulin mu kapamba. Zotsatira zake, ndikotheka kuwongolera kuchuluka kwa glucose m'magazi mutatha kudya.

    Incretinomimetics

    Mitundu ya incretin ndimankhwala omwe amatchedwa Exenatide. Kuchita kwake ndikufuna kuwonjezera kupanga insulin, yomwe imatheka chifukwa cha kutsekeka kwa shuga m'magazi. Nthawi yomweyo, kupanga glucagon ndi mafuta achilengedwe m'thupi kumachepa, njira yogaya chakudya imachepetsa, motero wodwala amakhala nthawi yayitali. Ma incretinomimetics ndi mankhwala ophatikiza pamodzi.

    Choyipa chachikulu chomwa kumwa ndi mseru. Monga lamulo, pakatha masiku 7-14 kuyambira chiyambi cha mankhwala, mseru umasowa.

    B-glucose zoletsa

    Acarbose ndi mankhwala ochokera ku gulu la b-glucosidase inhibitors. Acarbose sakusankhidwa kuti akhale mankhwala othandizira pochizira matenda ashuga, koma izi sizimachepetsa mphamvu yake. Mankhwala samalowa m'magazi ndipo samakhudza njira yopanga insulin.

    Mankhwalawa amalowa mu mpikisano ndi chakudya kuchokera ku chakudya. Zomwe zimagwira zimagwira ma enzyme omwe thupi limapanga kuti ligwetse zakudya zamafuta. Izi zimathandiza kuti achepetse kuchuluka kwake, komwe kumalepheretsa kulumpha kwakukulu m'magazi a shuga.

    Kanema: Dongosolo la Malysheva "Mankhwala okalamba. ACE zoletsa "

    Mankhwala osakanikirana

    Mankhwala othandizira odwala matenda a shuga amakhala ndi zovuta: Amaril, Yanumet, Glibomet. Amachepetsa kukana insulini ndipo amalimbikitsa kapangidwe kazinthu izi m'thupi.

    Amaryl imathandizira kupanga insulin ndi kapamba, komanso imakulitsa chiwopsezo cha maselo amthupi kwa icho.

    Ngati zakudya ndi kudula kwa mankhwala a hypoglycemic sikuloleza kuchita bwino, ndiye kuti wodwala amayikidwa Glibomet.

    Yanumet imalepheretsa shuga kugwa kwambiri m'magazi, zomwe zimalepheretsa shuga. Kulandila kwake kumakupatsani mwayi wowonjezera othandizira kudya komanso kuphunzitsa.

    Mankhwala obwera mwatsopano

    DPP-4 inhibitors ndi m'badwo watsopano wamankhwala omwe amathandizira odwala matenda a shuga. Sizikhudza kupanga kwa insulin ndi maselo a beta, koma amateteza polypeptide inayake ya glucan kuti isawonongedwe ndi enzyme DPP-4. Glucan-polypeptide iyi ndiyofunikira pakuchita bwino kwa kapamba, chifukwa imapangitsa kupanga insulin. Kuphatikiza apo, ma Dhib-4 ma inhibitors amathandizira magwiridwe antchito a mahomoni a hypoglycemic pochita ndi glucagon.

    Ubwino wa mankhwala am'badwo watsopano ndi monga:

    Wodwalayo alibe kuchepa kwenikweni kwa shuga m'magazi, chifukwa atatha kubwezeretsa kuchuluka kwa glucose kuzinthu zachilendo, mankhwalawa amasiya kugwira ntchito.

    Mankhwala osokoneza bongo samathandizira kuti muchepetse kunenepa.

    Zitha kugwiritsidwa ntchito ndimankhwala ena kupatula insulin ndi insulin receptor agonists.

    Choyipa chachikulu cha zoletsa za DPP-4 ndichakuti zimathandizira kusokoneza chimbudzi cha chakudya. Izi zimawonetsedwa ndi kupweteka kwam'mimba ndi mseru.

    Ntchitoyi siyikulimbikitsidwa kumwa mankhwalawa. Mayina a mankhwala am'badwo watsopano: Sitagliptin, Saksagliptin, Vildagliptin.

    Agonists a GLP-1 ndi mankhwala a mahomoni omwe amalimbikitsa kupanga insulin ndikuthandizira kubwezeretsa kapangidwe ka maselo owonongeka. Mayina a mankhwala: Viktoza ndi Baeta. Kudya kwawo kumapangitsa kuti anthu azinenepa kwambiri. AgP-1 agonists akupezeka monga njira zovomerezeka.

    Kanema: AgPP-1 agonists: kodi onse ndi ofanana?

    Kukonzekera kochokera ku mbewu

    Nthawi zina odwala matenda a shuga, wodwalayo amalimbikitsidwa kuti azikonzekera pogwiritsa ntchito mankhwala azitsamba. Amapangidwa kuti azichulukitsa kuchuluka kwa shuga m'magazi. Odwala ena amatenga zakudya zowonjezera zakudya zamankhwala odzaza, koma kwenikweni sizili choncho. Sadzalola kuchira.

    Komabe, sayenera kukanidwa. Mankhwalawa amathandizira kukonza thanzi la wodwalayo, koma chithandizo chiyenera kukhala chokwanira. Amatha kutengedwa pa gawo la prediabetes.

    Insulin ndi mankhwala azitsamba odziwika bwino kwambiri. Kuchita kwake ndikufuna kuchepetsa kuchuluka kwa kuyamwa kwa shuga m'matumbo. Izi zimachepetsa mulingo wake m'magazi.

    Kulandila kwa Insulin kumakupatsani mwayi wothandizira kupanikizika ndikuwongolera kulemera kwa wodwalayo. Itha kuthandizidwa onse kupewa matenda ashuga amtundu wa 2, komanso mankhwala ena. Ngati simukusokoneza njira yochizira, ndiye kuti mutha kukwaniritsa kusintha kwamisempha yamagazi. Pankhaniyi, ndikofunikira kutsatira chakudya osasiya njira zachipatala.

    Zolemba za insulin

    Ngati wodwala ali ndi matenda a shuga kwa zaka zambiri (kuyambira 5 mpaka 10), ndiye kuti wodwalayo amafunikira mankhwala enaake apadera. Odwala oterewa amapatsidwa jekeseni wa insulin kwakanthawi kapena mosalekeza.

    Nthawi zina insulin imapangidwa ngakhale zaka 5 zisanachitike. Dokotala amasankha motere ngati mankhwala ena sangalole kukwaniritsa zomwe mukufuna.

    M'mbuyomu, anthu omwe amamwa mankhwala osokoneza bongo ndikutsatira zakudya anali ndi chindoko kwambiri.Pomwe adalembedwa insulin, odwala awa kale anali ndi zovuta za matenda ashuga.

    Kanema: Mankhwala a shuga a insulin:

    Masiku ano, insulin imadziwika kuti ndiyo chinthu chothandiza kwambiri kutsitsa shuga. Mosiyana ndi mankhwala ena, ndizovuta kwambiri kulowa, komanso mtengo wake umakhala wokwera.

    Pafupifupi 30-40% ya odwala onse omwe ali ndi matenda ashuga amafunikira insulin. Komabe, lingaliro la insulin mankhwala liyenera kupangidwa kokha ndi endocrinologist malinga ndi kufufuza kwathunthu kwa wodwalayo.

    N`zosatheka kuzengereza ndi matenda a shuga. Makamaka olabadira zaumoyo wawo ayenera kukhala anthu onenepa kwambiri, omwe ali ndi vuto la kapamba, kapena otengera chibadwa cha matenda ashuga.

    Mankhwala ochepetsa shuga ndi oopsa chifukwa amatha kupangitsa kuti magazi achepe. Chifukwa chake, tikulimbikitsidwa kuti odwala ena azikhala ndi shuga pamlingo wokwanira (5-100 mmol / l).

    Chithandizo cha achikulire

    Ngati odwala okalamba akudwala matenda ashuga, ndiye kuti ayenera kusankhidwa ndi chisamaliro chapadera. Nthawi zambiri, odwala oterewa amalimbikitsidwa kumwa mankhwala okhala ndi metformin.

    Chithandizo ndi zovuta ndi mfundo zotsatirazi:

    Mu ukalamba, kuphatikiza pa matenda ashuga, munthu nthawi zambiri amakhala ndi zina zofanana ndi zina.

    Sikuti wodwala aliyense wokalamba angathe kugula mankhwala okwera mtengo.

    Zizindikiro za matenda ashuga zimatha kusokonezedwa ndikuwonetsedwa kwa matenda osiyana.

    Nthawi zambiri, matenda ashuga amapezeka mochedwa kwambiri, pomwe wodwala amakhala ndi zovuta kwambiri.

    Popewa matenda ashuga osapezeka m'mimba koyambirira, magazi amayenera kuperekedwa pafupipafupi kwa shuga atatha zaka 45-55. Matenda a shuga ndi matenda oopsa omwe amatha kutsatiridwa ndi zovuta m'magulu a mtima, kwamikodzo ndi hepatobiliary system.

    Zovuta zovuta za matendawa zimaphatikizaponso kutayika kwamaso ndikuduladula miyendo.

    Mavuto omwe angakhalepo

    Ngati chithandizo cha matenda amtundu wa 2 chachedwa, ndiye kuti zimakhudzana ndi ngozi zovuta. Chifukwa chake, zizindikiro zoyambirira za matendawa ziyenera kukhala chifukwa chowunikira kwathunthu.

    Njira yosavuta kuyeza shuga wamagazi ndikuyitenga kuchokera ku chala chanu kapena kuchokera mu mtsempha. Ngati matendawa atsimikiziridwa, ndiye kuti dokotala amasankha njira imodzi payekha yopangira mankhwala.

    Iyenera kumangidwa potsatira mfundo izi:

    Mafuta a m'magazi amafunika kuyezedwa pafupipafupi.

    Wodwala ayenera kukhala ndi moyo wokangalika.

    Choyambirira ndichakudya.

    Kumwa mankhwala kuyenera kukhala mwadongosolo.

    Zingatheke kuthandizira kuchuluka kwa shuga m'magazi ndi njira yophatikizira yamankhwala.

    Ngati malingaliro azachipatala sanatsatidwe, ndiye kuti chiwopsezo chokhala ndi zotsatirazi zimawonjezeka:

    Matenda a shuga a retinopathy omwe amawonongeka.

    Njira zochizira zikasankhidwa moyenera, zimatha kupewa matendawa ndikupewa zovuta zina. Mankhwala amatha kuperekedwa ndi adokotala okha.

    Mapiritsi otchuka kwambiri ochepetsa shuga

    Gome ili pansipa likufotokoza za mapiritsi otchuka kwambiri ochepetsa shuga.

    Mapiritsi Atiwiti Otchuka a 2:

    Gulu ndi chachikulu yogwira pophika

    Gulu - mankhwala a sulfonylurea (glycoslazide)

    Gulu - sulfonylureas (glibenclamide)

    Maziko - metformin (gulu - Biguanides)

    Gulu - DPP-4 inhibitor (maziko - sitagliptin)

    Gulu la DPP-4 inhibitor (kutengera vildagliptin)

    Maziko - liraglutide (gulu - glucagon-ngati peptide-1 receptor agonists)

    Gulu - mankhwala a sulfonylurea (maziko - glimepiride)

    Gulu - lembani 2 sodium glucose transporter inhibitor (base - dapagliflosin)

    Gulu - lembani 2 glucose transporter inhibitor (base - empagliflozin)

    Mankhwala ochizira matenda a shuga a 2 akhoza kukhala m'magulu otsatirawa:

    Glucagon-ngati peptide-1 receptor agonists.

    Dipeptidyl peptinase-4 zoletsa (glisitins).

    Lembani 2 sodium glucose transporter inhibitors (glyphlozines). Awa ndi mankhwala amakono.

    Kukonzekera kwa kuphatikiza, komwe nthawi yomweyo kumakhala zinthu ziwiri zazikulu.

    Kodi njira yabwino kwambiri yothetsera matenda a shuga ndi iti?

    Chimodzi mwa mankhwala othandiza kwambiri ndi Metformin. Sichimayambitsa zovuta zoyipa. Komabe, odwala nthawi zambiri amatsekula m'mimba. Kuti mupewe kupindika, pang'onopang'ono muyenera kuwonjezera kuchuluka kwa mankhwalawa. Komabe, Metformin, ngakhale ili ndi zopindulitsa, sizingathetse shuga. Munthu ayenera kukhala ndi moyo wathanzi.

    Metformin imatha kutengedwa ndi odwala ambiri omwe ali ndi matenda ashuga. Sichikuperekedwa kwa anthu omwe ali ndi vuto la impso, komanso matenda enaake. Analogue yochokera kunja kwa Metformin ndi mankhwala Glucofage.

    Mankhwala osakanikirana a shuga Yanumet ndi Galvus Met ndi mankhwala othandiza, koma mtengo wake ndi wokwera.

    Matenda a shuga a Type 2 nthawi zambiri amakula chifukwa chakuti thupi silitha kuyamwa chakudya chamafuta komanso chakudya. Chifukwa chake, ndi kuchuluka kwa shuga m'magazi, ndikofunikira kusintha kwambiri moyo wanu ndi zakudya. Mankhwala okha sikokwanira.

    Wodwala akapanda kusiya zinthu zovulaza, ndiye kuti zotsalira za kapamba zimatha posakhalitsa. Insulin yomwe iliyo idzasiya kupangidwa kwathunthu. Panthawi imeneyi, palibe mankhwala, ngakhale okwera mtengo kwambiri, omwe angathandize. Njira yokhayo yomwe ingakhalire jakisoni wa insulini, apo ayi munthuyo atha kudwala matenda ashuga ndipo amwalira.

    Odwala omwe ali ndi matenda a shuga sakhala ndi moyo mpaka nthawi yomwe mankhwalawo amaleka kugwira ntchito. Nthawi zambiri odwala oterewa amayamba kugundidwa ndi mtima kapena kuwonongeka, ndipo osati kulephera kwathunthu kwa kapamba kuchita ntchito zake.

    Mankhwala aposachedwa a shuga

    Nthawi zambiri, mankhwala ochizira matenda amtundu wa 2 amavomerezeka ngati mapiritsi. Komabe, kukulira kwa mankhwala aposachedwa kwambiri monga ma jakisoni kungasinthe kwambiri zinthu. Chifukwa chake, asayansi omwe amagwira ntchito ku kampani ya Danish a Novo Nordiks adapanga mankhwala omwe amachepetsa insulin, omwe amagwira ntchito molingana ndi chinthu chomwe chimatchedwa liraglutide. Ku Russia amadziwika kuti Viktoza, ndipo ku Europe amapangidwa pansi pa dzina la Saksenda. Adavomerezedwa ngati mankhwala atsopano ochizira matenda a shuga kwa odwala omwe ali ndi kunenepa kwambiri komanso BMI yoposa 30.

    Ubwino wa mankhwalawa ndikuti umathandiza kulimbana ndi kunenepa kwambiri. Izi ndizosowa kwa mankhwalawa. Ngakhale kunenepa kwambiri kumatha kuchititsa kuti matenda ashuga azikhala kwambiri. Kafukufuku akuwonetsa kuti kugwiritsa ntchito liraglutide kuloleza kuchepetsa kulemera kwa odwala ndi 9%. Palibe mankhwala ochepetsa shuga omwe "angadzitamande" chotere.

    Mu 2016, kafukufuku adamalizidwa pomwe anthu 9,000 adatenga nawo gawo. Zinatha zaka 4. Zinapangitsa kutsimikizira kuti kutenga liraglutide kumapangitsa kuti muchepetse chiopsezo chokhala ndi matenda amtima. Pamenepo, chitukuko cha Novo Nordics sichinamalize. Asayansi apereka chinthu china chatsopano chochizira matenda a shuga otchedwa Semaglutide.

    Pakadali pano - mankhwalawa ali pachiyeso cha zamankhwala, koma tsopano gulu lonse la asayansi lazindikira. Izi ndichifukwa choti Semaglutide amatha kuchepetsa mwayi wokhala ndi matenda amtima mwa odwala omwe ali ndi matenda ashuga. Maphunzirowa anali okhudza odwala 3,000. Kuchiza ndi mankhwala atsopano amenewa kunatenga zaka ziwiri.Zinali zotheka kukhazikitsa kuti chiopsezo cha matenda a mtima ndi sitiroko chatsika ndi 26%, zomwe ndizabwino kwambiri.

    Odwala onse omwe ali ndi matenda a shuga ali pachiwopsezo cha matenda a mtima ndi sitiroko. Chifukwa chake, chitukuko cha asayansi aku Danish chimatha kutchedwa kuti chitukuko chenicheni, chomwe chidzapulumutsa miyoyo ya anthu ambiri. Onse liraglutide ndi semaglutide amayenera kuthandizidwa pang'onopang'ono. Kuti mukwaniritse zochizira, muyenera kuyika jakisoni imodzi yokha pa sabata. Chifukwa chake, tsopano titha kunena motsimikiza kuti shuga si chiganizo.

    Za adotolo: Kuyambira 2010 mpaka 2016 Othandizira pachipatala chachipatala chapakati chaumoyo Na. 21, mzinda wa elektrostal. Kuyambira mu 2016, agwira ntchito ku malo ozindikira matenda No. 3.

    Ndi mankhwala ati omwe amachiza matenda amtundu woyamba?

    Chithandizo chachikulu cha matenda a shuga 1 ndi insulin. Mwa odwala ena, kagayidwe kakang'ono ka glucose kamakhala kobvuta. Pankhaniyi, adokotala atha kukupatsani mapiritsi okhala ndi metformin, kuphatikiza jakisoni wa insulin. Mankhwalawa mwa anthu onenepa kwambiri amachepetsa kufunika kwa insulini komanso kusintha shuga. Musayembekezere mothandizidwa ndi mapiritsi kuti musiye kwathunthu jakisoni wa insulin.

    Chonde dziwani kuti metformin imayikidwa pakati pa anthu omwe apezeka ndi matenda a shuga, omwe kusefukira kwa impso kumatsika kuposa 45 ml / min. Kwa odwala matendawa a mtundu woyamba, kumwa mankhwalawa kulibe ntchito. Kuphatikiza pa metformin, mapiritsi ena aliwonse omwe ali ndi matenda amtundu wa 1 sagwira ntchito. Mankhwala ena onse ochepetsa shuga ndi othandizira matenda a shuga 2 okha.

    Momwe mungachiritsire matenda a shuga a 2 opanda madokotala ndi mankhwala?

    Zomwe muyenera kuchita:

    1. Sinthani ku chakudya chamafuta ochepa.
    2. Mvetsetsani mapiritsi otchuka a shuga omwe ali ovulaza. Kanani kuzitenga nthawi yomweyo.
    3. Mwakuthekera, ndikwanzeru kuyamba kumwa mankhwala omwe ndi otsika mtengo komanso osavulaza, chinthu chogwira ntchito chomwe ndi metformin.
    4. Chitani masewera olimbitsa thupi osachepera.
    5. Kuti mubweretse shuga kwa anthu athanzi 4.0-5,5 mmol / L, mungafunike jakisoni wambiri wa insulin mu Mlingo wotsika.

    Njirayi imakulolani kuti muthane ndi matenda amtundu wa 2 popanda kumwa mapiritsi owopsa komanso kulankhulana pang'ono ndi madokotala. Ndikofunikira kuti azitsata boma tsiku ndi tsiku, kuti azikhala ndi moyo wathanzi. Palibe njira yosavuta yodzitetezera ku zovuta za matenda ashuga lero.



    Insulin kapena mankhwala: momwe mungadziwire njira yamankhwala?

    Cholinga chamankhwala othandizira odwala matenda ashuga ndi kuthandiza kuti shuga azikhazikika ku 4.0-5,5 mmol / L, monga momwe zimakhalira ndi anthu athanzi. Choyamba, zakudya zamafuta ochepa zimagwiritsidwa ntchito pamenepa. Imakhala ndi mapiritsi ena, omwe amaphatikizika ndi metformin.

    Kuchita masewera olimbitsa thupi kumathandizanso - osachepera kuyenda, komanso kuthamanga. Izi zimatha kutsitsa shuga mpaka 7-9 mmol / L. Jakisoni wochepa wa insulin amafunika kuwonjezeredwa kuti abweretse kuchuluka kwa shuga m'magoli.

    Musakhale aulesi kubayirira insulin ngati mukufuna. Kupanda kutero, vuto la matenda ashuga lipitiliza kukula, ngakhale pang'ono ndi pang'ono.

    Mukaphunzira kupanga jakisoni mwachangu, pomwepo, ndiye kuti sangakhale wopweteka. Kuti mumve zambiri, onani "Insulin Administration: Kuti ndi Motani."

    Chithandizo cha boma chimalimbikitsa odwala matenda ashuga kuti azidya zakudya zopanda pake, kenako ndikubaya mankhwala akuluakulu a insulin kuti athetse shuga wambiri. Njirayi imabweretsa odwala kumanda ali ndi zaka zapakati, kuchepetsa nkhawa zomwe amapeza pantchito zapenshoni.

    Kodi mungandipangirekonso mankhwala a gawo loyamba la matenda ashuga kuti asadutse?

    Onani chithandizo chothandiza cha matenda ashuga amtundu wa 2. Mukayamba kugwiritsa ntchito kumayambiriro kwa matendawa, ndiye kuti mutha kukhala ndi shuga, monga anthu athanzi, popanda jakisoni wa insulin.

    Osayesa kuchiritsa matenda anu a shuga kamodzi kokha komanso mothandizidwa ndi mapiritsi ena ochulukitsa.Mankhwala othandiza komanso otetezeka kuposa kukonzekera kwa metformin kulibe.

    Mankhwala amakono amakono komanso okwera mtengo ali ndi malire. Kuchita kwawo ndi kofatsa, ndipo zotsatirapo zake zimakhala zazikulu.

    Ndi mankhwala ati ochepetsa magazi omwe ali m'badwo wotsiriza?

    Mankhwala atsopano ochepetsa shuga amtundu wa 2 sodium glucose cotransporter inhibitors. Ophunzirawa ali ndi mankhwala osokoneza bongo a Forsig, Jardins ndi Invokana. Osathamangira kukagula iwo ku pharmacy kapena kuyitanitsa pa intaneti ndikutumiza. Mapiritsi awa ndiokwera mtengo komanso amayambitsa zovuta zoyipa. Unikani zambiri mwatsatanetsatane za iwo, kenako osankha momwe angawathandizire.

    Mankhwala 2 a shuga amtundu wanji samayambitsa mavuto?

    Metformin imathandizira odwala matenda ashuga ndipo nthawi zambiri samayambitsa zovuta zoyipa. Kuchokera pakugwiritsa ntchito mapiritsi awa pali m'mimba. Koma zitha kupewedwa ngati mugwiritsa ntchito mitunduyi yolimbikitsidwa pang'onopang'ono. Ndi mapindu ake onse, metformin sili vuto lina lokhudza matenda ashuga ndipo sangathe kusintha kusintha kwa moyo wathanzi.

    Metformin imakhala yotetezeka kwa odwala onse, kupatula kwa odwala omwe amalephera kwambiri ndi impso. Onaninso zotsutsana musanayambe mankhwala ndi mankhwalawa. Glucophage ndi njira yoyambira yoikika ya metformin. Galvus Met ndi Yanumet ndi amphamvu, koma mapiritsi ophatikiza odula kwambiri.

    Pafupifupi mankhwala ena onse amtundu wa matenda ashuga a 2, kupatula metformin, amachititsa zotsatira zoyipa komanso zoyipa. Kapena osathandiza, ndi ma dummies. Werengani za gulu lirilonse la mankhwala omwe adalipo pansipa patsamba lino.


    Zoyenera kuchita ngati palibe mankhwala omwe akuthandizira kuchepetsa shuga?

    Matenda a 2 a shuga amapezeka makamaka chifukwa chosalolera chakudya, komanso chifukwa chokhala phee. Kuchuluka kwa shuga kwa magazi kuyenera kumalimbikitsa wodwalayo kusintha moyo wabwino, osangomwa mankhwala.

    Wodwala matenda ashuga akapitiliza kudya zakudya zosavomerezeka, kapamba wake amatha kutopa. Kupanga insulin yanu kumatha. Pambuyo pake, palibe mapiritsi, ngakhale atsopano kwambiri komanso okwera mtengo kwambiri, sangathandizenso kuchepetsa shuga. Kufunika koyamba kuti mupeze jakisoni wa insulin, apo ayi abwera ndi matenda a shuga komanso imfa.

    Odwala omwe ali ndi matenda a shuga a mtundu wachiwiri samakhala ndi moyo kuti awone mankhwalawa atasiya kuthandiza. Nthawi zambiri vuto la mtima kapena kugunda limawapititsa kumanda chamba chisanathe.

    Mankhwala abwino kwambiri a shuga 2 a odwala okalamba ndi ati?

    Vuto lalikulu la odwala okalamba omwe ali ndi matenda a shuga a 2 ndi kusowa kwa chilimbikitso. Ngati palibe chikhumbo chotsatira boma, ndiye kuti mapiritsi abwino kwambiri komanso okwera mtengo sangathandize. Achinyamata nthawi zambiri amalephera kukonza chiwongolero cha matenda ashuga mwa makolo achikulire chifukwa cha kusawalimbikitsa, komanso nthawi zina chifukwa cha matenda a dementia. Okalamba omwe ali ndi chidwi chokhala ndi moyo wautali komanso wopanda olumala amagwiritsa ntchito bwino njira zamankhwala othandizira odwala matenda ashuga zomwe zafotokozedwa patsamba lino. Mankhwala a Metformin amawathandiza.

    Mankhwalawa atha kutumwedwa ndi odwala matenda ashuga omwe sanakhale ndi nthawi yokhala ndi kulephera kwa impso.

    Kodi ma diuretics abwino ndi ati kwa odwala matenda ashuga?

    Zakudya zama carb zotsika zimachotsa madzimadzi ochuluka mthupi, zimachepetsa edema kapena kuzichotsa kwathunthu, kuphatikiza kuthamanga kwa magazi. Izi zimachitika mwachangu komanso zamphamvu. Imayamba kuonekera pakatha masiku awiri kapena atatu. Ndi kuthekera kwakukulu, chifukwa cha kusintha kwa zakudya, mudzatha kukana kuthira okodzetsa, ndipo nthawi yomweyo mankhwala ena othandizira matenda oopsa komanso kulephera kwa mtima.

    Ngati komabe edema yaying'ono imakuvutitsani nthawi ndi nthawi, funsani kuti taurine ndi chiyani. Chida ichi chimagwira ntchito pazakudya zowonjezera zakudya.Mwa okodzetsa ovomerezeka, pokhapokha ngati Indapamide ichulukitsa zochizira matenda amtundu wa 2. Ndipo zina zonse zimakhudza shuga wamagazi. Pambuyo posintha kudya chamafuta ochepa, kufunikira kwenikweni kumawatenga kokha mwa odwala omwe ali ndi vuto la mtima kwambiri. Werengani apa momwe mungachiritsire matendawa kwathunthu kuti mukwaniritse bwino.

    Kodi pali mankhwala othandiza kuyeretsa mtsempha wamagazi a matenda ashuga?

    Mankhwala ndi njira zoyeretsera ziwiya masiku ano zilibe. Ma charlatans okha ndi omwe angakulonjezeni kuti muyeretsa ziwiya zanu za malo atherosclerotic. Mwachidziwikire, m'zaka zochepa, njira zimapangidwa kuti ziyeretse komanso kupangitsanso mitsempha yamagazi. Koma mpaka nthawi ino ndikofunikira kupulumuka. Mpaka nthawi imeneyo, khalani ndi moyo wathanzi kuti mupewe matenda a atherosulinosis. Tsatirani malangizo a matenda ashuga omwe amapezeka patsamba lino tsiku lililonse.

    Ndi kuzizira kotani komwe kungatengedwe ndi odwala matenda ashuga?

    Chitani nawo popewa ndi kuchiza chimfine pogwiritsa ntchito njira zomwe zafotokozedwa m'buku la Komarovsky, "Health's Child and Common Sense of jamaa".

    Njirazi sizigwira ntchito kwa ana okha, komanso kwa akulu. Nthawi zambiri ndi chimfine, anthu amatenga paracetamol kapena aspirin. Mwambiri, mankhwalawa samakhudza shuga wamagazi mwa odwala matenda a shuga. Sayenera kukhala mwa mtundu wa manyumwa okoma. Musatengeke kwambiri ndi mapiritsi a antipyretic omwe amagulitsidwa pa counter. Ngati vuto la wodwalayo silikuyenda bwino patapita masiku ochepa, pitani kuchipatala.

    Kuzizira ndi matenda ena opatsirana, monga lamulo, kumawonjezera shuga m'magazi odwala matenda ashuga ndikuchepetsa chidwi cha minofu kuti insulin. Odwala a shuga a Type 2 akulimbikitsidwa kuti apange jekeseni wa insulin, ngakhale atakhala kuti sakonda. Kupanda kutero, chimfine chitha kukulitsa matendawa kwa moyo wanu wonse. Imwani madzi ambiri ndi tiyi wa zitsamba, chifukwa cha chimfine, pamakhala chiwopsezo chachikulu cha matenda a shuga omwe amayamba chifukwa cha kuperewera kwa madzi m'thupi.

    Kodi mungandilangizireko mankhwala opangira matenda ashuga?

    Pokhudzana ndi dzanzi m'miyendo yoyambitsidwa ndi matenda amitsempha ya m'mimba, palibe mankhwala omwe amathandiza. Njira yokhayo yothanirana ndi chithandizo chokwanira cha matenda ashuga pogwiritsa ntchito njira zomwe zafotokozedwera patsamba lino. Ndikofunikira kuti shuga asungidwe mkati mwa 4.0-5.5 mmol / L. Ngati mutha kuyendetsa bwino kuchuluka kwa shuga, ndiye kuti zizindikiro za neuropathy zidzatha pakapita nthawi. Nkhani yabwino ndiyakuti ichi ndi chosinthika. Madokotala ena amakonda kupereka nicotinic acid, reopoliglyukin, pentoxifyline, actovegin ndi mankhwala ena ambiri ofanana. Awa si mankhwala, koma zakudya zowonjezera mphamvu zomwe sizothandiza. Samathandiza konse, amatha kuyambitsa ziwopsezo zina ndi zina.

    Kuchepetsa ululu m'miyendo, dokotala atha kukulemberani:

    • antidepressants (serotonin reuptake inhibitors),
    • opiates (tramadol),
    • anticonvulsants (pregabalin, gabapentin, carbamazepine),
    • lidocaine wa.

    Mankhwala onsewa ali ndi zovuta zoyipa. Zitha kugwiritsidwa ntchito pokhapokha ngati akuwongolera ndi dokotala. Yesani kuchita popanda iwo konse. Mavuto ndi ziwiya zamiyendo nthawi zambiri amagwirizanitsidwa ndi systemic atherosulinosis, yomwe imasokoneza kayendedwe ka magazi mthupi lonse. Mwambiri, atatenga kuyesedwa kwa magazi kwa cholesterol, dokotala amupatsa mankhwala omwe amapezeka.

    Kodi njira yabwino yochizira cholesterol yapamwamba mu shuga ndi iti?

    Mankhwala akuluakulu a cholesterol okwanira ndi ma statins. Amayikidwa kuti aletse kukula kwa atherosulinosis, kupewa matenda a mtima ndi sitiroko. Odwala omwe ali ndi matenda ashuga, mankhwalawa amawonjezera shuga wamagazi ndi 1-2 mmol / L. Komabe, amatha kuchepetsa kwambiri vuto la kugunda kwa mtima ndi sitiroko. Chifukwa chake, chiŵerengero cha zovulaza kuti chizipindula nthawi zambiri chimakonda chithandizo ndi mapiritsi awa. Mutha kudziwa zambiri za ma statins apa. Dziwani ngati zili zomveka kuti mutenge.

    Magulu ena a mankhwalawa ndi mafakiteriya, othandizira ma bile acid, komanso mankhwala a Ezetimibe, omwe amaletsa kuyamwa kwa cholesterol ya chakudya m'mimba. Mankhwalawa amatha kutsitsa cholesterol yamagazi, koma samachepetsa kufa, mosiyana ndi ma statins. Sayenera kumwedwa kuti asawononge ndalama zamapiritsi okwera mtengo komanso kuti asayang'anitsidwe ndi zotsatila zake.

    Onani vidiyo ya Dr. Bernstein yokhudza momwe matenda ashuga, cholesterol yayikulu, ndi kuchepa kwa mahomoni a chithokomiro zimalumikizidwa. Mvetsetsani momwe mungawerengere chiopsezo cha vuto la mtima ndi zizindikiro za "zoyipa" komanso "zabwino" cholesterol m'magazi. Dziwani za chiopsezo cha mtima ndi misempha chomwe muyenera kuyang'anira, kupatula cholesterol.

    Kodi bambo wodwala matenda ashuga atha kutenga Viagra kapena mankhwala ena osathandiza?

    Zotsatira zakufufuza zikunena kuti Viagra, Levitra ndi Cialis sizimakhudza njira yoyipa ya shuga, kapenanso kusintha kayendedwe kake. Choyamba, yesani mankhwala oyamba omwe amagulitsidwa ku malo ogulitsa mankhwala. Pambuyo pake, mutha kutenga chiopsezo cholamula anzanu achi India otsika mtengo pa intaneti ndikufanizira momwe amagwirira ntchito ndi mapiritsi oyambirirawo. Ndalama zonsezi zimagwira ntchito kwa munthu aliyense payekhapayekha, ndizosatheka kulosera zamtsogolo. Fufuzani zotsutsana musanagwiritse ntchito Viagra, Levitra ndi Cialis.

    Funsani momwe kuchuluka kwa testosterone m'magazi anu kumasiyanirana ndi msinkhu wanu wachilengedwe. Ngati ndi kotheka, funsani katswiri wa urologist kuti muwongolere. Dr. Bernstein adanenanso kuti kukweza testosterone m'magazi pazaka zapakati pa zaka kumasintha shuga wa magazi mwa amuna omwe ali ndi matenda a shuga a 2. Osayesa kumwa mapiritsi a "potraestine" potency, omwe amagulitsidwa m'masitolo ogonana, ndipo makamaka, kuyesa mosasamala ndi zowonjezera za testosterone.

    Mankhwala 2 a shuga: gulu

    Mutha kupita ku malangizo a mankhwalawa omwe amakusangalatsani. Koma ndikwabwino kuti ndiyambe kuwerenga kuti ndi magulu ati a mankhwalawa a mtundu wachiwiri wa shuga omwe alipo, momwe amachitira, momwe amasiyana, zabwino ndi zovuta zawo. Lotsatira ndi chidziwitso chofunikira chomwe madokotala ndi opanga mapiritsi angafune kubisala kwa odwala. Mankhwala a shuga a Type 2 ndi msika waukulu, madola mabiliyoni pachaka pakupita ndalama. Mankhwala ambiri amapikisana nawo. Ambiri aiwo ndi okwera mtengo, amathandiza bwino, komanso amavulaza odwala. Dziwani chifukwa chake adokotala amakupatsirani mankhwala ena, osati ena.

    Dzina lamankhwalaGulu, chinthu chogwira ntchito
    DiabetesSulfonylureas (Glyclazide) Derivatives
    ManinilDerivatives of sulfonylureas (glibenclamide)
    Siofor ndi GlyukofazhBiguanides (metformin)
    JanuviaDipeptidyl peptidase-4 inhibitor
    (sitagliptin)
    GalvusDipeptidyl peptidase-4 inhibitor
    (vildagliptin)
    VictozaGlucagon-ngati Peptide-1 Receptor Agonist (liraglutide)
    AmarilSulfonylurea zotumphukira (glimepiride)
    ForsygaType 2 sodium glucose cocransporter inhibitor (dapagliflozin)
    JardinsType 2 sodium glucose cocransporter inhibitor (empagliflozin)

    Mankhwala a shuga a Type 2 agawidwa m'magulu otsatirawa:

    • Biguanides (metformin)
    • Derivatives of sulfonylureas (CM)
    • Ma glinids (meglitinides)
    • Pangamira (glitazones)
    • Α-glucosidase zoletsa
    • Glucagon ngati Peptide Receptor Agonists - 1
    • Dipeptidyl Peptidase-4 Inhibitors (Gliptins)
    • Type 2 sodium glucose cocransporter inhibitors (glyphlosins) - mankhwala aposachedwa
    • Mankhwala osakanikirana okhala ndi zosakaniza ziwiri zogwira ntchito
    • Insulin

    Pansipa amafotokozedwa mwatsatanetsatane lililonse la maguluwa, magawo amapereka mndandanda wa mankhwala omwe adatumizidwa kunja ndi mtengo wawo. Werengani malangizo oti mugwiritsire ntchito mapiritsi omwe mudawalemba. Dziwani kuti ndi a gulu liti, kenako werengani zabwino zake, zovuta zake, zisonyezo, zotsutsana, zoyipa.

    Metformin (Siofor, Glucofage)

    Metformin, yomwe ndi gawo la gulu la Biguanide, ndiye piritsi lachiwiri la shuga. Chida ichi chakhala chikugwiritsidwa ntchito kuyambira m'ma 1970, chakhala chikuvomerezedwa ndikuvomerezedwa ndi mamiliyoni a odwala. Zatsimikizira kugwira ntchito kwake komanso chitetezo. Metformin imachulukitsa chidwi cha minyewa kupita ku insulin, komanso imachepetsa kupanga shuga m'chiwindi. Chifukwa cha izi, shuga m'magazi amatsitsidwa mwa odwala matenda ashuga omwe onenepa kwambiri. Metformin sangathe kuchiritsa matenda ashuga kwathunthu, koma amachedwetsa kukula kwa zovuta komanso amachepetsa chiopsezo cha matenda amtima.

    Odwala nthawi zambiri amapeza zabwino zonsezi popanda zovuta zoyipa. Zowona, pakhoza kukhala matenda otsegula m'mimba komanso matenda ena am'mimba. Zolemba za mankhwala a Glucophage ndi Siofor amafotokoza momwe mungapewere. Dr. Bernstein akuti mankhwala oyambilira Glucofage amakhala olimba kuposa Siofor, ndipo ngakhale zili zochepa, fanizo lotsika mtengo la mayiko a CIS. Odwala ambiri olankhula Chirasha okhala ndi matenda a shuga a 2 amatsimikizira izi. Ngati mungakwanitse kutenga Glucophage yotsimikiziridwa bwino, ndibwino kuti musayese Siofor ndi mapiritsi ena otsika mtengo a Metformin.

    Ma glinids (meglitinides)

    Glinides (meglitinides) ndi mankhwala omwe ali ofanana ndi sulfonylureas. Kusiyanako ndikuti amayamba kuchita zinthu mwachangu, koma zotsatira zake zimakhala zakanthawi. Malangizowa akutsimikizira kuti odwala matenda ashuga amwe mankhwalawa musanadye kuti shuga asadzuke pakudya. Amawalembera odwala omwe amadya mosasamala. Clinides amayenera kutayidwa pazifukwa zomwezo ndi mankhwala a sulfonylureas. Amachepetsa kapamba, amayambitsa kuchuluka kwa thupi. Mulole shuga wotsika kwambiri azitsogolera ku hypoglycemia. Mwambiri, kuonjezera ngozi yakufa.

    MankhwalaZogwira ntchitoMa analogi okwera mtengo kwambiri
    NovoNormRepaglinideDiaglinide
    StarlixNateglinide-

    Α-glucosidase zoletsa

    Α-glucosidase inhibitors ndi mankhwala omwe amalepheretsa kuyamwa kwa chakudya cham'mimba. Pakadali pano, gululi limaphatikizapo imodzi yokha ya mankhwala a Glucobay mu Mlingo wa 50 ndi 100 mg. Zomwe zimagwira ndi acarbose. Odwala samakonda kuti mapiritsiwa ayenera kumwedwa katatu patsiku, samathandiza kwenikweni ndipo nthawi zambiri amachititsa kuti m'mimba musakhale bwino. Mwachidziwitso, Glucobay amayenera kuchepetsa thupi, koma machitidwe ake palibe kuchepa kwa anthu onenepa omwe amathandizidwa ndi mapiritsi awa. Kudya zakudya zamafuta ndikugwiritsa ntchito mankhwala nthawi yomweyo kuti tilepheretse kuyamwa kwawo ndikopenga. Ngati mutsatira zakudya zama carb otsika, ndiye kuti palibe chifukwa chogwiritsira ntchito acarbose komanso kuvutika chifukwa cha zotsatira zake zoyipa.

    Glucagon ngati Peptide Receptor Agonists - 1

    Glucagon-ngati peptide-1 receptor agonists ndi mankhwala amtundu wa 2 wa matenda am'badwo waposachedwa. Zokha, zimakhudza kwambiri shuga wamagazi, koma amachepetsa chilakolako cha kudya. Chifukwa chakuti wodwala matenda ashuga amadya pang'ono, kuwongolera kwake kumayenda bwino. Glucagon ngati peptide - 1 receptor agonists amachepetsa kuyenda kwa chakudya chodyedwa kuchokera m'mimba kupita m'matumbo, ndikukulitsa kumverera kwodzaza. Dr. Bernstein akuti mankhwalawa ndi abwino kwa odwala omwe ali ndi vuto la kusasamala. Tsoka ilo, amapezeka jakisoni ngati insulin. Mapiritsi, kulibe. Ngati mulibe vuto lakudya, sizomveka kuwamveka.

    MankhwalaZogwira ntchitoPafupipafupi
    VictozaLiraglutideKamodzi patsiku
    BaetaExenatide2 pa tsiku
    Baeta LongExenatide wokhala ndi nthawi yayitaliKamodzi pa sabata
    LycumiaLixisenatideKamodzi patsiku
    KukhazikikaDulaglutideKamodzi pa sabata

    Glucagon-like peptide-1 receptor agonists ndi mankhwala atsopano omwe ndi okwera mtengo koma osagulitsika mtengo. Mankhwalawa angayambitse kapamba, koma chiwopsezo ndichochepa.Kwa odwala omwe ali ndi matenda a shuga a mtundu wachiwiri omwe ali ndi vuto losakonda kusamala, akhoza kukhala othandiza kwambiri. Amapatsirana odwala matenda ashuga omwe ali kale ndi kapamba. Panthawi yamankhwala, amafunika kuyeserera magazi pafupipafupi kuti ateteze pancreatic amylase. Ngati zotsatirapo zake zikukula, siyani kumwa mankhwalawo.

    Mankhwala a Bayeta, omwe amagwiritsidwa ntchito pafupipafupi kawiri pa tsiku, ndi osavuta kugwiritsa ntchito pochita. Zomwe mwakumana nazo pogwiritsa ntchito Victoza, zomwe muyenera kuziba kamodzi patsiku. Jekeseni wotsekemera amayenera kuperekedwa musanadye, pomwe wodwalayo ali pachiwopsezo chachikulu cha kudya kwambiri. Odwala ambiri omwe ali ndi matenda amtundu wa 2 amakhala ndi chizolowezi chomadya kwambiri madzulo, usiku, koma izi sizofanana kwa aliyense. Glucagon-ngati peptide - agonists 1 omwe amafunika kulowetsedwa kamodzi pa sabata awonekera posachedwa. Mwina atha kukhala othandiza kwambiri pakulimbitsa chakudya.

    Dipeptidyl Peptidase-4 Inhibitors (Gliptins)

    Dipeptidyl peptidase-4 inhibitors (glyptins) ndi mankhwala atsopano a mtundu 2 wa shuga, omwe amapezeka kumapeto kwa 2010s. Amatsitsa shuga wamagazi popanda kufooketsa kapamba komanso chiopsezo cha hypoglycemia. Mapiritsi awa nthawi zambiri samayambitsa zotsatira zoyipa, koma sizotsika mtengo, koma amachita mopanda mphamvu. Zitha kuthandizidwa ndi Glucophage kapena Siofor, ngati kukonzekera kwa metformin sikungathandize mokwanira, ndipo simukufuna kuyambitsa jakisoni wa insulin. Ma gliptins sachepetsa kudya, mosiyana ndi glucagon-peptide - 1 receptor agonists. Nthawi zambiri zimapangitsa kuti wodwalayo asamalemere - sizimapangitsa kuti ziwonjezeke kapena kuchepa thupi.

    MankhwalaZogwira ntchito
    JanuviaSitagliptin
    GalvusVildagliptin
    OnglisaSaxagliptin
    TrazentaLinagliptin
    VipidiaAlogliptin
    SaterexGozogliptin

    Ma Patent a Gliptin sanathere ntchito. Chifukwa chake, ma analogi otsika mtengo a dipeptidyl peptidase-4 inhibitors sanapezekepo.

    Lembani 2 sodium glucose cocransporter zoletsa

    Mtundu 2 wa sodium glucose cocransporter inhibitors (glyphlosins) ndi mankhwala aposachedwa omwe amachepetsa shuga la magazi. Ku Russian Federation, mankhwala oyamba kuchokera pagululi adagulitsidwa mu 2014. Odwala onse omwe ali ndi matenda amtundu wa 2 omwe amasangalala ndi nkhani zamankhwala awo samvera kwambiri glyphlosins. Kukhala kofunikira kwa inu kumvetsetsa momwe mankhwalawa amagwirira ntchito. Mwa anthu athanzi, shuga yamagazi amasungidwa m'malo osiyanasiyana a 4-5-5,5 mmol / L. Ngati ikwera mpaka 9-10 mmol / l, ndiye kuti gawo lina la glucose limapita ndi mkodzo. Chifukwa chake, m'magazi ake amachepetsa. Kugwiritsa ntchito mitundu 2 ya sodium glucose cotransporter zoletsa kumapangitsa impso kuti zitsitse shuga mu mkodzo ngakhale ndende yake m'magazi ndi 6-8 mmol / l. Glucose, yemwe thupi silingathe kuyamwa, amatulutsidwa mkodzo mwachangu, m'malo mozungulira magazi ndikuwonjezera kukula kwa zovuta za shuga.

    MankhwalaZogwira ntchito
    ForsygaDapagliflozin
    JardinsEmpagliflozin
    AttokanaKanagliflozin

    Glyphlosins sikuti ndi vuto la matenda ashuga amtundu wa 2. Ali ndi zolakwika zazikulu. Odwala amakhumudwa kwambiri ndi mtengo wawo wokwera. M'zaka zikubwerazi, munthu sayenera kuyembekezera kuwoneka kwa mtengo wotsika mtengo wa mankhwala aposachedwa. Kupatula mtengo, pali vuto la mavuto.

    Glyphlosins samayambitsa mavuto akangomaliza kukonzekera. Pafupipafupi kuyendera kuchimbudzi (polyuria) kukuchulukirachulukira. Pakhoza kukhala kuchepa thupi, makamaka odwala matenda ashuga, komanso kuchepa kwakukulu kwa magazi. Awa ndi mavuto ang'onoang'ono. Zotsatira zake zazitali ndizowopsa. Kukhalapo kwa glucose mu mkodzo kumapangitsa malo abwino kuti chitukuko cha bowa ndi mabakiteriya azisungunuka ku urethra. Ili ndi vuto lafupipafupi komanso lalikulu la odwala omwe ali ndi matenda a shuga a 2 omwe amathandizidwa ndimankhwala a Forsig, Jardins kapena Invokana.

    Choyipa koposa, ngati ma virus amafika impso kudzera mu urethra ndikupangitsa pyelonephritis.Kutupa kwa matenda a impso kumakhala kosatheka. Kumwa maantibayotiki olimba atha kumuwumitsa, koma osakuwonongerani. Akamaliza maphunzirowo, mabakiteriya omwe ali mu impso amayambiranso msanga mzimu wawo womenya nkhondo. Ndipo pakupita nthawi, amatha kuyamba kukana maantibayotiki.

    Yang'anirani zakudya zamafuta ochepa zomwe zimathandiza komanso sizivulaza. Ngati sichoncho, ndiye kuti zingakhale zomveka kupereka mankhwala a Forsig, Invokan ndi Jardins kwa odwala matenda ashuga. Popeza zakudya zabwino komanso zaulere zili m'manja mwanu, palibe chifukwa chomwera ndi glyphlosins. Pyelonephritis ndi tsoka losasinthika. Matenda amadzimadzi a m'mimba nawonso samabweretsa chisangalalo. Musadziyike pachiwopsezo chosafunikira. Zakudya, mapiritsi a metformin, zolimbitsa thupi, ndi jakisoni wochepa wa insulin ndizokwanira kuthana ndi matenda amtundu wa 2.

    Mankhwala osakanikirana a shuga a mtundu 2

    MankhwalaZinthu zogwira ntchito
    Galvus Met Vildagliptin + Metformin
    Janumet Sitagliptin + metformin
    Kutalika kwa ComboglizSaxagliptin + Metformin Wochedwa
    GentaduetoLinagliptin + metformin
    ChikalakalaInsulin degludec + liraglutide

    38 ndemanga pa "Mankhwala A shuga

    Moni, Seryozha! Ndili ndi zaka 63, zolemera makilogalamu 82. Kwa mwezi ndi theka, mukamadya zakudya zamafuta ochepa, shuga osala kudya amatsikira ku 6-7, nthawi zina kutsika. Kuchotsa piritsi loyipa la Amaril. Tsopano ndimatenga glucophage 1000, ma PC 2 patsiku, mapiritsi ena awiri a Galvus ndi Levemir amaba magawo 18 usiku ndi 8 m'mawa. Ndiuzeni, ndikasiyanitse chiyani paphwando? Dokotala samalangiza kalikonse; amasemphana ndi zakudya zamafuta ochepa. Ndili ndi insulin yanga yanga mthupi langa - pamlingo wa 2.7-10.4, zotulukazo zake ndi 182.80. Komanso C-peptide ndi 0.94 ng / ml pamlingo wa 0.78-5.19. Ndataya 7 kg. Chonde ndiuzeni yankho la funso langa. Ndipo tikukuthokozani kwambiri chifukwa chakudya!

    Sanawonetse kutalika, koma, mwina, si basketball, pali zolemetsa zochuluka.

    kusala kudya kumachepa mpaka 6-7, nthawi zina kutsika. Kuchotsa piritsi loyipa la Amaril.

    Ndili ndi insulin yanga yanga mthupi langa - pamlingo wa 2.7-10.4, zotulukazo zake ndi 182.80. Komanso C-peptide ndi 0.94 ng / ml pamlingo wa 0.78-5.19.

    M'magazi anu, makamaka ndi insulin yomwe imabayidwa yomwe imazungulira. Zotsatira zakuwunikira kwa C-peptide ndizochepa. Izi zikutanthauza kuti pali insulini yopanga pang'ono. Koma izi ndizabwino koposa nthawi yomwe sizipangidwa konse! Samalirani kapamba wanu mwa kutsata zakudya zamafuta ochepa. Sungani ndi jakisoni wa insulin, ngati pakufunika.

    Ndiuzeni, ndikasiyanitse chiyani paphwando?

    Ndimayesa kuletsa Galvus, makamaka kuti ndisunge ndalama.

    Ndibwino kuti muganize zowonjezera zolimbitsa thupi kuposa kuchepetsa mapiritsi.

    Kukana jakisoni wa mankhwala Levemir - osawerengetsa kwenikweni. Ngati mukukwanitsa kuchita izi kwa nthawi yayitali, ikani insulini pafupi ndi matenda kapena chimfine.

    Kutalika kwanga ndi masentimita 164. Ndimalandira mapiritsi aulere, chifukwa ndine wolumala. Ndipo, momwe ndikumvera, chilichonse chimakhala chofanana. Ndipo ngati shuga ndi ochepa, ndiye chiyani?

    Ndimalandira mapiritsi aulere chifukwa ndalemala

    Wokondedwa wogulitsa mankhwala kwaulere - khalani ndi moyo wabwino

    momwe ndikumvera, zonse zimakhala zofanana.

    Sindingadalire m'malo mwanu

    Ndipo ngati shuga ndi ochepa, ndiye chiyani?

    Pankhaniyi, muyenera kuchepetsa mlingo wa insulin.

    Mutha kukumana ndi vutoli ngati muwonjezera zochitika zolimbitsa thupi.

    Mwa anthu omwe amakhala ndi moyo wongokhala, chidwi cha insulini chimacheperanso pakapita nthawi, m'malo mochulukirachulukira. Mlingo, m'malo mwake, uyenera kuchuluka.

    Moni Ndili ndi zaka 58, kutalika 173 masentimita, kulemera kwa makilogalamu 81, pantchito yausilikali, ndimagwira. Type 2 shuga kuyambira 2011. Matendawa: Matenda amitsempha yama mtima, matenda a mtimaKuti ndimalipire matenda a shuga, ndimaba jakisoni wa Levemir m'mayunitsi 14 ndipo ndimatenga Glucofage 2 kawiri pa tsiku, pa 850 mg. Shuga samakhala wokwera kuposa 7-8. Cardiologist adandipatsa mankhwala: Concor, Enam, Dibikor, Zilt ndi Atoris. Kodi mankhwalawa amadetsa matenda anga a shuga? Momwe ndikumvera, Concor imasokoneza kufalikira kwaziphuphu, ndipo Atoris amenya chiwindi. Tithokoze chifukwa cha yankho lanu!

    Momwe ndikumvera, Concor imasokoneza kufalikira kwaziphuphu

    Zotsatira zomwe mudawonetsera sizothandiza. Concor yoyambirira yaku Germany ya Concor ndi imodzi mwazabwino kwambiri komanso zosasokoneza beta-blockers. Ngati muli ndi umboni weniweni, pitilizani kuutenga.

    Kodi ndikufunika kutenga ma statins, pezani apa - Ht. //Centr-zdorovja.com/statiny/

    Cardiologist adandipatsa mankhwala: Concor, Enam, Dibikor, Zilt ndi Atoris. Kodi mankhwalawa amadetsa matenda anga a shuga?

    Mwawonetsedwa mankhwala amakono omwe ali ndi zovuta zochepa. Sakhala ndi vuto lililonse la glucose metabolism.

    Matendawa: Matenda amitsempha yama mtima, matenda a mtima

    Chiwopsezo cha kufa chifukwa cha vuto la mtima kapena kulephera kwa mtima ndi kwambiri. Chifukwa chake, ndibwino kumwa mankhwala mwakhama.

    Ndikadakhala kuti ndikadakhala inu, ndikadawerenga nkhani yokhudza kupewa matenda a mtima - http://centr-zdorovja.com/profilaktika-infarkta/ - ndikuchita zomwe ukunena kuwonjezera pa kumwa mapiritsi. Ndi kusintha kwa kukhala bwino komanso zizindikiro za kuthamanga kwa magazi, mutha kupatsa pang'ono pang'onopang'ono mlingo wa mankhwala. Mwina ena mwa iwo adzasiyidwa kwathunthu. Koma kutsatira izi siziyenera kutero. Cholinga chachikulu ndikudziteteza ku vuto la mtima ndi kukula kwa kulephera kwa mtima.

    Palibe chomwe muyenera kunyadira nacho, chifukwa Zizindikiro ndizokwera nthawi 1.5 kuposa anthu athanzi. Phunzirani mtundu wachiwiri wa mankhwala othandizira odwala matenda ashuga - http://endocrin-patient.com/lechenie-diabeta-2-tipa/ - ndikuthandizidwa nawo.

    Wokondedwa Sergey, ndikufuna malangizo anu. Ndili ndi zaka 62, kulemera kwa 55 makilogalamu, kutalika masentimita 164. Ndakhala ndikudwala matenda ashuga a 2 kwa zaka 8. Kuphatikiza apo, autoimmune chithokomiro ndi hypothyroidism ndi zaka 15. Sindingathe kutsitsa shuga lero. Zakudya ndi masewera sizithandiza mokwanira. Ndikulowera moyo wokangalika, sindidandaula chilichonse, koma hemoglobin ya glycated ndi 10.6%. Ndibaya mankhwala a Viktoza 1.2 m'mawa, ndimakhalanso ndi Glucophage 1000 madzulo. Zakudya zama carb otsika, komabe C-peptide idatsikira ku 0.88. Mantha kwambiri! Dokotala wakomweko akuumirira kuti azachipatala azifulumira kuti asankhe insulin. Koma ndimakhala ku Lugansk, ndimavuto onse omwe amabwera. Ndimawopa insulini kwambiri, koma ndikufuna kukhala ndi moyo kwambiri! Kuyembekezera mawu owona. Zikomo

    Ndili ndi zaka 62, kulemera kwa 55 makilogalamu, kutalika masentimita 164. Ndakhala ndikudwala matenda ashuga a 2 kwa zaka 8.

    Mukudziwa molakwika. Matenda anu amatchedwa matenda a shuga a LADA. Muyenera kubaya insulin pang'ono. Inde, inde, kutsatira kwambiri zakudya zamafuta ochepa.

    Ine jekeseni wa mankhwala Viktoza 1.2 m'mawa, komabe ndimatenga Glucophage 1000 madzulo.

    Zida zonsezi ndi zopanda ntchito kwa inu. Amapangidwira anthu onenepa kwambiri, mafuta ambiri mthupi.

    Sindikumvetsa zomwe mukuopa. Insulin siyabwino kwambiri kuposa jakisoni wa Viktoza omwe mumachita kale.

    Kuthamanga pa insulin!

    Shuga ya m'mawa nthawi zonse imakhala 7-8, masana imatsika mpaka 5-6. Tsiku lililonse, kupanikizika m'mawa ndi 179/120. Ndimamwa verapamil - itayamba kuoneka ngati yachilendo. Cholesterol 7 - Ndikutenga atorvastatin. Ndimatenga Concor kuchokera pamtima wanga. Ndimayesetsa kutsatira zakudya, koma nthawi zina shuga amakwera kufika pa 12-13. Tsopano zaka 10. Ndili ndi zaka 59, kutalika 164 cm, 60 cm. Tithokoze yankho.

    Kuti mupeze yankho, muyenera kufunsa funso.

    Zaka 66 zaka, kutalika 153 masentimita, kulemera 79 makilogalamu. Ndili ndi matenda a shuga a mtundu wa 2 kwa zaka 10. Ndinkakonda kumwa metformin, shuga umatha 8-10. Tsopano, kuchuluka kwa kusefukira kwa impso kwatsika mpaka 39, motero metformin inathetsedwa. Ndimatenga gliclazide 120 mg m'mawa, komanso galvus m'mawa ndi madzulo. Mishuga ya shuga imachokera ku 9.5 mpaka 12 pamimba yopanda kanthu. Pa upangiri wa endocrinologist, mayunitsi 14 a Lantus anali olumikizidwa. Komabe, msuzi wa shuga sukusintha modabwitsa. Kuthamanga kwamahatchi kumachitika pafupipafupi mpaka 16 pakati pa tsiku. Kodi chifukwa chiyani insulin siyothandiza? Ponena za iye, kuti atabayidwa - jekeseni wa shuga sanasinthe. Panalibe kusintha kwakukulu pakudya. Chifukwa chiyani Kodi ndizomveka kupitilirabe kubayirira insulin ngati sikuchepetsa kwambiri shuga. Kapena ndizotheka popanda iwo pamapiritsi omwewo?

    Mwinanso kuwonongeka chifukwa chophwanya malamulo osungira, zambiri - http://endocrin-patient.com/hranenie-insulina/

    Kodi ndizomveka kupitilirabe kubayirira insulin ngati sikuchepetsa kwambiri shuga. Kapena ndizotheka popanda iwo pamapiritsi omwewo?

    Mumawerenga tsambali ndipo mukupitilirabe kumwa gliclazide. Komanso kuchepa kwa kusefukira kwa impso mpaka 39 ml / min sikukuchititsani mantha. Izi zikutanthauza kuti mulingo woyenera wokwanira. Kupereka uphungu uliwonse sikuwona mfundo.

    Ndili ndi zaka 54. Kutalika kwa 172 cm, kulemera kwa 90 kg. Ndikudwala pafupifupi chaka. Zotsatira zoyesedwa - glycosylated hemoglobin 9.33%, C-peptide 2.87. Ndimamwa metformin 500 mg, piritsi limodzi katatu patsiku ndikudya. Shuga amakhala ndi 6.5-8, koma nthawi zina, makamaka madzulo, zimachitika 9.8-12.3. Mwinanso ndiyenera kukulitsa mlingo madzulo? Zikomo

    Mwinanso ndiyenera kukulitsa mlingo madzulo?

    Muli ndi hemoglobin wokwera kwambiri. Kufunika koyamba kuti mupeze jekeseni wa insulin, kenako ndikuganiza zokulitsa mapiritsi.

    Zikomo kwambiri. Ndikukufunirani zabwino padziko lapansi. Malowa ndi abwino. Ndaphunzira zinthu zambiri zothandiza. Iyemwini zaka 35 sanali kudwala. Ndipo tsopano, matenda ashuga. Koma ichi sichiri matenda. Adasintha moyo wake. Zikomo ndi tsamba lanu.

    Zikomo chifukwa cha ndemanga. Padzakhala mafunso - funsani, musachite manyazi.

    Yankho lomaliza kwa Anatoly sizodziwikiratu. Ngati C-peptide 2.87, mwachiwonekere, insulin yake imapangidwa mokwanira ndipo vuto ndikuti maselo samazindikira. Nanga bwanji kuwonjezerapo ndi jakisoni? Bwanji osachulukitsa mlingo wa metformin? Kodi hemoglobin ya glycated palokha si yopweteka? Ndipo kutsika kwake kumachitika kwambiri, ngakhale shuga wabwinobwino m'magazi. Bwanji kuthamangitsa chizindikiro ichi - chimodzimodzi, mwachangu sichitha. Zikomo

    Yankho lomaliza kwa Anatoly sizodziwikiratu. Ngati C-peptide 2.87, mwachiwonekere, insulin yake imapangidwa mokwanira

    Wodwala uyu ali ndi shuga wambiri wamwazi. Amafunikira kuwombera pansi ndi jakisoni wa insulin. Kupanda kutero, matendawa angayambike. Ngati muli ndi mwayi, pakapita nthawi mutha kukana jekeseni tsiku ndi tsiku, kuwongolera matenda a shuga okha ndi zakudya, mapiritsi ndi maphunziro a thupi. Kubaya jakisoni kuposa kufa ndi zovuta za shuga.

    Kodi hemoglobin ya glycated palokha si yopweteka?

    Mafuta am'magazi amawonongeka osati hemoglobin yokha, komanso mapuloteni ena, omwe amatsogolera pakupanga zovuta za shuga

    Bwanji osachulukitsa mlingo wa metformin?

    Izi zitha kuchitika, komabe muyenera kubayirira insulin pankhaniyi.

    Mzimayi, wazaka 58, kutalika 154 cm, kulemera 78 kg, shuga adawululidwa posachedwa, pafupifupi miyezi itatu yapitayo. Endocrinologist adalemba 850 mg metformin pambuyo pa chakudya cham'mawa komanso chamadzulo, komanso subetta kanayi pa tsiku. Kodi mudamvapo chilichonse chokhudza subetta, mankhwala othandiza kapena ayi? Ndinawerenga patsamba limodzi kuti izi ndizakudya zomwe sizothandiza. Mwa njira, shuga yothamanga sikugwera pansi 8. Ndimasunga chakudya.

    Kodi mudamvapo chilichonse chokhudza subetta, mankhwala othandiza kapena ayi? Ndinawerenga patsamba limodzi kuti izi ndizakudya zomwe sizothandiza.

    Ichi ndi njira yothetsera vuto. Osamapita kwa dotolo yemwe adamulamula panonso. Yesani kukalipira dokotala uyu pa intaneti, kulikonse komwe kungatheke.

    Mwa njira, shuga osala kudya satsika pansi 8. Ndimasunga chakudya.

    Yesetsani magazi a C-peptide - http://endocrin-patient.com/c-peptid/. Ngati ndi kotheka, yambani kubayitsa insulini mu Mlingo wochepa.

    Ndili ndi zaka 83, kutalika kwa 160 cm, kulemera 78 kg. Ndimakhala pamtunda wa 1200 m, zachidziwitso, hypoxia. Matenda a shuga adayamba mchaka cha 2001, adatha zaka 10 chifukwa cha chakudya komanso kukhala pagombe, ndiye kuti a Diabeteson MV adalembedwa. Ndakhala ndikuletsa matenda oopsa posachedwapa ndi mapiritsi a Concor - 12.5 mg m'mawa, masana - Lozap, sizithandiza nthawi zonse. Kupanikizika kumadzuka usiku. Chokani posachedwa 65-70. Hypothyroidism, mankhwala sanapangidwe chifukwa cha kulekerera bwino, zikuwoneka kuti linayamba kale kwambiri. Myocardial dystrophy, kukulira kumanzere kwa atrium, aortic mitral valavu kusakwanira 2 tbsp. Pyelonephritis mu chikhululukiro.

    Kodi m'malo Diabeteson? Mankhwala onse ali ndi zotsutsana. Ndidayesa Glucophage, koma ndikuopa chifukwa cha impso. Ndimayesetsa kudya zakudya zamafuta ochepa, koma sizikhala bwino. Palibe wofunsa, palibe endocrinologist mkati mwa radius ya 100 km. Inde, shuga 6-7.

    Izi zikutanthauza kuti impso zawonongeka kwambiri.Zingakhale bwino kumayesa magazi ndi mkodzo.

    Ndidayesa Glucophage, koma ndikuopa chifukwa cha impso.

    Kodi m'malo Diabeteson? Mankhwala onse ali ndi zotsutsana.

    Mwachidziwitso, muyenera kusintha kwambiri moyo wanu. Pafupifupi - muli ndi zaka zambiri ndipo zovuta zina sizingasinthe. Choyipa kwambiri, impso zimawonongeka. Sizokayikitsa kuti mudzatha kuchita bwino kwambiri. Ndikukulangizani kuti musiye zonse monga zili.

    Moni, moni. Kodi ndingamwe mankhwala Trazhenta? Sindinapeze chidziwitso patsambalo. Zikomo patsogolo.

    Kodi ndingamwe mankhwala Trazhenta?

    Choyamba, muyenera kubweretsa mlingo wa metformin tsiku lililonse. Kenako, ngati mukufuna komanso kupezeka kwa mwayi wazachuma, mutha kuwonjezera mankhwalawa. Kapena ena ofanana nawo, ochokera pagulu lomweli. Ngati mulingo wa c-peptide m'magazi ndi wotsika, ndiye kuti mapiritsi onsewa sangakupulumutseni kuti musabayidwe insulin, kuwonjezera pakutsatira zakudya.

    Moni. Amayi ali ndi zaka 65, kutalika 152 cm, kulemera 73 kg, adataya kulemera kwakukulu mwezi watha, matenda a shuga adawululidwa sabata ndi theka lapitalo. M'mawa, shuga osala kudya anali 17.8 mmol, adotolo adatchulanso piritsi limodzi la Jardins m'mawa ndi 2 glucophage Long 750 mg wamadzulo. Lero m'mawa, shuga osala kudya ndi 9.8., Madzulo layamba kufika ku 12. Kodi ndizotheka kuti muchoke kukatenga ma jardins ndikusintha kokha ku glucophage? Kodi angachite bwanji? Zimagwirizana ndi zakudya. Glycated hemoglobin 11.8%.

    Amayi ali ndi zaka 65, kutalika 152 masentimita, kulemera kwa 73 kg, adatopa kwambiri mwezi watha, matenda a shuga adawululidwa

    Monga lamulo, anthu okalamba amakana kusintha, kotero kusintha chiwongolero chawo cha shuga sikungatheke. Simuyenera kugwiritsa ntchito nthawi yambiri ndi kuchita izi.

    Mutha kupewa mavuto kunyumba ngati muwerenga tsamba lino mosamala ndikutsatira malangizowo.

    Ndili ndi zaka 53, kutalika 163 cm, kulemera kwa makilogalamu 83. Type 2 shuga mellitus adapezeka 3 masiku apitawa, mulingo wa HbA1c mpaka 6.5%, kunenepa kwambiri kochokera kumakanidwe osakanikirana. Tafotokozedwa tebulo 9 Pambuyo pa miyezi itatu, kuyesedwa kwa glycosylated hemoglobin. Ndikumvetsetsa kuti kulemera kwambiri komwe ndidapeza pazaka ziwiri zapitapo kunagwira ntchito. Zachidziwikire, ndidzachichotsa. Koma, ndichifukwa chiyani madokotala endocrinologist sanandipatse mankhwala alionse?

    Kulemera kwambiri komwe ndidapeza m'zaka ziwiri kunandithandizanso. Zachidziwikire, ndidzachichotsa.

    chifukwa chiyani dokotala sanandipatse mankhwala alionse kwa endocrinologist?

    Cholinga cha adotolo ndikukukankhirani kutali mwachangu. Ndikuganiza kuti, munjira mudakali ndi mzera waukulu.

    Ndi okhawo omwe angakhale ndi chidwi chopulumutsa odwala matenda ashuga.

    Moni Sergey!
    Amayi ali ndi zaka 83, akudwala matenda a shuga 2. Nthawi yotsiriza adatenga glybomet m'mawa ndipo nthawi ya 5 p.m., adayika levemir 10 usiku. Mwazi wa magazi unkayendetsedwa bwino. Panali sitiroko pakugwa. Ananena kuti pambuyo pa stroke, kutenga Metformin ndizoletsedwa. Amayala mayunitsi a M50 6 m'mawa, magawo 4 madzulo, pang'onopang'ono kuchuluka kwa mayeso kukhala magawo 34 patsiku, shuga anali 15-18 mpaka 29. Miyezi iwiri yamazunzo, tsopano levemir abwerera usiku wa mayunitsi 14, m'mawa ndi masana, mapiritsi a 3.5 adatengedwa. M'mawa, shuga adakwanitsa 9, anali 13, koma masanawa adadzuka mpaka 15. Patsamba lanu ndawerenga kuti maninil ali ndi zotsatira zoyipa. Ndikupemphani kuti mualangize zomwe zingasinthidwe ndi mannil pamenepa, zomwe zimaphatikizidwa ndi levemir. Ndikhala wokondwa kwambiri yankho lanu. Zikomo

    Amayi ali ndi zaka 83, akudwala matenda a shuga 2.

    Monga lamulo, ndi anthu okalamba ndibwino kusiya zonse monga zilili, chifukwa amakana kusintha.

    Muli ndi chibadwa choyipa. Ngati muwerenga tsambalo mosamala ndikutsatira malangizowo, mutha kupewa matenda ashuga kunyumba, kulumala ndi kufa msanga.

    Zambiri zothandiza m'nkhaniyi komanso mayankho a akatswiri Sergey Kushchenko mu ndemanga - zikomo. Koma mafunso adatsala. About Diabeteson kwalembedwa kuti sizithandiza, koma zimapweteka. Glucophage ndikulimbikitsidwa, koma akuti ndikoyenera kuwopa ngati pali zovuta ndi impso.

    Zomwe ndingagwiritse ntchito kwa amayi anga omwe ali ndi shuga 14.4, ngati akadali ndi kuthamanga kwa magazi, amasiya chamitsempha cha m'mimba, chifuwa cham'mimba, pyelonephritis, ndipo tsopano akuwathandizira mu urology ya cystitis ndi levofloxacin dropper. Kuchokera pazotanganidwa, madotolo adapanga jakisoni wa Dibazole ndi mapiritsi a Valodip. Chifukwa cholandirira chakudya Mezim.

    Kwa sabata limodzi kuchipatala - osagona. Ndimakonda kumwa mapiritsi ogona Sonnat - kodi ndizotheka tsopano?

    Amayi ali ndi zaka 62, kulemera kwake ndi makilogalamu 62, monga kutalika kwa 164 cm.Pazaka zingapo zapitazi, adachepetsa makilogalamu 7-10 ndipo masomphenya ake adatsika. Kukoka pafupipafupi usiku kwawonekera posachedwa. Sindinatsatirepo chakudya ndipo sindinamwe mankhwala a shuga, chifukwa sindinakayikire za izi.

    Kodi pali kusiyana kotani pakati pa Lada ndi mtundu wachiwiri wa matenda ashuga? Ndi iti kwa ife? Zakudya zayamba. Dotolo adayambitsa Dibazol, Actiseril, Nootropil, ogona Moyo. Thandizani kupulumutsa Amayi.

    Zomwe ndingagwiritse ntchito kwa amayi anga omwe ali ndi shuga 14.4, ngati akadali ndi kuthamanga kwa magazi, amasiya chamitsempha yamagazi, chifuwa chachikulu cha chotupa, pyelonephritis. Pazaka zingapo zapitazi, adachepetsa makilogalamu 7-10 ndipo masomphenya ake adatsika. Kukoka pafupipafupi usiku kwawonekera posachedwa.

    Kwa sabata limodzi kuchipatala - osagona. Ndimakonda kumwa mapiritsi ogona Sonnat - kodi ndizotheka tsopano?

    Sindikudziwa, kukaonana ndi dokotala

    Kodi pali kusiyana kotani pakati pa Lada ndi mtundu wachiwiri wa matenda ashuga? Ndi iti kwa ife?

    Muli ndi T2DM yakale, yosinthira ku T1DM.

    Kodi ndizotheka kuti matenda ashuga amtundu wa 2 asinthe kupita kumalo osala kudya okwanira cyclic? Njira iti yomwe ndiyothandiza kwambiri mwakuthupi - masiku kapena atatu? Kapena kutsatira mndandanda wamasiku onse wa 8/16, komwe maola 8 ndi nthawi yopumula ndipo maola 16 ndi nthawi yopumira?

    Kodi ndizotheka kuti matenda ashuga amtundu wa 2 asinthe kupita kumalo osala kudya okwanira cyclic?

    Kusala kudya sikuti kuthana ndi vuto la anthu odwala matenda ashuga, koma kumawonjezera phokoso.

    Ngati simukukonda kufa ndi njala, musadzikakamize, koma ingotsatira zakudya zamafuta ochepa zomwe zafotokozedwa patsamba lino. Ngati mukufunabe kufa ndi njala, chabwino, yesani, kukhala ndi thanzi. Musaiwale kuyang'anira shuga ndikuyika insulin yayitali ngati pakufunika.

    Masana abwino
    Mwamuna wanga ali ndi matenda ashuga a 2, amatenga theka la 2 m'mawa, m'mawa. Kusala shuga inali 5-5.5. Pakazizira, shuga adakwera 14 ndipo sabwerera wamba. Kulandila kunakulirakonso mlingo wonse wa 2 mg. Kuyambira lero, timayesa dzira lomwe limakhala ndi mandimu ochokera ku wowerengeka. Mwina mungasinthane ndi mankhwala ena? Diabetes kapena metformin?

    Ndapereka imelo yanu ku kampani yothandizana nayo yomwe ikuchita zamaliro. M'masiku akubwerawa mudzalumikizidwa ndikupatsidwa mawonekedwe abwino.

    Ndadwala ndi DM 2 kwazaka 16. Shuga anali wabwinobwino kale. Koma posachedwa, m'mimba yopanda 13.7. Ndimalola Metformin 1000 ndi Diabeteson MV. Ndili ndi matenda khumi ndi awiri omwe adadziwika kuyambira mchaka cha 1986, ndine wobweretsa madzi mu ngozi ya Chernobyl. Kuyambira 2006, adasiya kuyendera zipatala. Ndikupangidwa ndekha. Zowona, ndalama zambiri zimachoka. Ndikupita kuchipatala cha Ministry of Emergency Situations, ndidayitanidwa posachedwa. Ndili ndi zaka 69. Hypertension, ischemia, angina pectoris, hyperthyroidism. Ndinayesa mankhwala okwera mtengo - osagwiritsa ntchito. Kangapo konse anagonjera kukopa achinyengo pa intaneti - zopanda nzeru. M'mbuyomu kutaya thupi kuyambira 149 kg mpaka 108 kg. Tsopano braked. Wokhulupirira, ine ndisala kudya zaka 20: Upangiri zoyenera kuchita. Zikomo

    Zonsezi zikufotokoza

    Kuthetsa mavuto ndi cholowa cha malo anu.

    Glucophage ndi Glucophage Kutalika kwa Type 2 shuga

    Mankhwala Glucofage amatha kuchepetsa kuchepa kwamphamvu kwa chakudya

    Mtundu woyamba wa mankhwalawa umatengera mankhwala omwe amachepetsa kwambiri kuyamwa kwa chakudya chamafuta, omwe amakhala ndi phindu pa kapamba. Mlingo wapamwamba wa Glucophage ndi 500 kapena 850 mg yogwira ntchito, yomwe ikuyenera kugwiritsidwa ntchito mpaka katatu patsiku. Tengani mankhwalawo ndi chakudya kapena mukangomaliza kudya.

    Popeza mapiritsiwa amayenera kumwedwa kangapo patsiku, chiopsezo cha zotsatirapo zake chimakula kwambiri, chomwe odwala ambiri sakonda. Kuti achepetse kupsa mtima kwa mankhwalawa pathupi, mawonekedwe a Glucophage adasintha. Njira yotalikilapo yamankhwala imakuthandizani kuti mumwe mankhwalawa kamodzi kokha patsiku.

    Mbali ya Glucofage Long ndikutulutsa pang'onopang'ono, komwe kumaletsa kulumpha kwamphamvu mu metformin m'magazi a madzi am'magazi.

    Yang'anani!Mukamagwiritsa ntchito mankhwala a Glucofage, kotala la odwala limatha kukhala ndi zizindikiro zosasangalatsa mu mawonekedwe a matumbo colic, kusanza komanso kulawa kwamphamvu kwamkamwa. Ndi zotsatirazi zoyipa, muyenera kusiya mankhwalawo ndikuthandizira mankhwala.

    Mankhwala a Type II a shuga

    Mankhwalawa ndi a gulu la a GLP-1 receptor agonists. Amagwiritsidwa ntchito ngati syringe yopangidwa mwapadera, yomwe ndi yabwino kupereka jakisoni ngakhale kunyumba.Baeta ili ndi mahomoni apadera omwe ali ofanana ndendende ndi zomwe chakudya chamagaya chimapanga chakudya chikalowa. Kuphatikiza apo, pali kukondoweza pa kapamba, chifukwa chomwe amayamba kupanga insulin mwachangu. Jakisoni amayenera kupanga ola limodzi asanadye. Mtengo wa mankhwalawa umasiyanasiyana 4800 mpaka 6000 rubles.

    Imapezekanso mu syringe, koma chifukwa cha formula yowonjezera imakhala ndi mphamvu yayitali mthupi lonse. Izi zimakuthandizani kuti mupeze jakisoni kamodzi patsiku, komanso ola limodzi musanadye. Mtengo wapakati wa Victoza ndi ma ruble 9500. Mankhwala ayenera kuvomerezedwa mufiriji yokha. Ndikofunikanso kuyambitsa nthawi yomweyo, zomwe zimakupatsani mwayi wothandizira ntchito yam'mimba komanso kapamba.

    Mankhwala amapezeka piritsi. Mtengo wapakati wa phukusi limodzi ndi ma ruble 1700. Mutha kumwa Januvia mosasamala za chakudya, koma ndikofunikira kuchita izi pafupipafupi. Mlingo wapamwamba wa mankhwalawa ndi 100 mg yogwira ntchito kamodzi patsiku. Kuchiza ndi mankhwalawa kumatha kuchitika ngati mankhwala okhawo oponderezera zizindikiro za matenda ashuga, komanso kuphatikiza ndi mankhwala ena.

    Mankhwala ndi a mankhwala a gulu la zoletsa DPP-4. Tikaledzera monga zovuta, odwala ena nthawi zina amakhala ndi mtundu woyamba wa matenda a shuga, omwe amakakamiza odwala kumwa insulin nthawi zonse akangodya. Onglisa amagwiritsidwa ntchito ngati monotherapy komanso kuphatikiza pamodzi. Ndi mitundu iwiri ya chithandizo, mlingo wa mankhwalawa ndi 5 mg yogwira ntchito kamodzi patsiku.

    Zotsatira zakugwiritsa ntchito mapiritsi a Galvus zimapitirira kwa tsiku limodzi

    Mankhwalawa amakhalanso a gulu la DPP-4 zoletsa. Gwiritsani ntchito Galvus kamodzi pa tsiku. Mlingo woyenera wa mankhwalawa ndi 50 mg yogwira ntchito, mosasamala kanthu za kudya. Mphamvu ya kugwiritsa ntchito mapiritsi imapitirira tsiku lonse, zomwe zimachepetsa mphamvu ya mankhwalawa thupi lonse. Mtengo wamba wa Galvus ndi ma ruble 900. Monga momwe anachitira Onglisa, kukula kwa matenda ashuga amtundu 1 ali m'gulu la zovuta zomwe zimagwiritsidwa ntchito ndi mankhwalawa.

    Yang'anani!Mankhwalawa amalimbikitsa zotsatira zamankhwala ndi Siofor ndi Glucofage. Koma kufunikira kwa kugwiritsidwa ntchito kwawo kuyenera kufotokozedwa mu chilichonse.

    Mankhwala othandizira chidwi cha maselo ku insulin

    Mankhwala amapezeka mu mawonekedwe a mapiritsi mu 15 mpaka 40 mg yogwira ntchito. Ndondomeko komanso mlingo wa wodwala aliyense umasankhidwa payokha poganizira glucose wamagazi. Nthawi zambiri, chithandizo chimayamba ndi mlingo wa 15 mg, kenako lingaliro lingachitike pakufunika kokulirapo kwa Actos. Mapiritsi ndi oletsedwa kugawana ndi kutafuna. Mtengo wapakati wa mankhwala ndi ma ruble 3000.

    Zimapezeka kwa anthu ambiri, zomwe zimagulitsidwa pamtengo phukusi la ma ruble 100-300. Mankhwalawa amayenera kumwa mwachangu ndi chakudya kapena pambuyo pake. Mlingo woyamba wa yogwira mankhwala ndi 0,5 mg kawiri tsiku lililonse. Amaloledwa kutenga mlingo woyambirira wa 0,87 mg wa formin, koma kamodzi patsiku. Pambuyo pake, mlingo wa sabata iliyonse umakulitsidwa pang'onopang'ono mpaka umafika 2-3 g. Ndi zoletsedwa mwamphamvu kupitirira muyeso wa chinthu yogwira mu magalamu atatu.

    Mtengo wapakati wa mankhwala ndi ma ruble 700. Glucobay mwanjira ya mapiritsi amapangidwa. Mlingo wachitatu wa mankhwalawa amaloledwa tsiku lililonse. Mlingo umasankhidwa mwa aliyense payekha, poganizira kuyezetsa magazi. Pankhaniyi, ikhoza kukhala 50 kapena 100 mg ya chinthu chachikulu. Tengani Glucobai ndi chakudya choyambirira.Mankhwala amakhalabe ndi ntchito kwa maola asanu ndi atatu.

    Mankhwalawa awonekera posachedwa m'mashelefu apabizinesi ndipo sanalandirebe kufalitsa kokwanira. Kumayambiriro kwa mankhwalawa, odwala amalimbikitsidwa kumwa piouno kamodzi pa tsiku Mlingo wa 15 mg yogwira ntchito. Pang'onopang'ono, mlingo wa mankhwalawa ukhoza kuwonjezeka mpaka 45 mg imodzi. Muyenera kumwa piritsi nthawi yayikulu chakudya nthawi yomweyo. Mtengo wapakati wa mankhwala ndi ma ruble 700.

    Zotsatira zazikulu mukamagwiritsa ntchito mankhwalawa zimatheka pothandizira odwala omwe ali ndi matenda osokoneza bongo omwe ali ndi kunenepa kwambiri. Mutha kutenga Astrozone osasamala chakudya. Mlingo woyambirira wa mankhwalawa ndi 15 kapena 30 mg yogwira ntchito. Ngati ndi kotheka komanso kusathandiza kwa mankhwalawa, dokotala angaganize kuwonjezera mlingo wa tsiku lililonse mpaka 45 mg. Mukamagwiritsa ntchito Astrozone mu zochitika zosowa kwambiri, odwala amapanga zotsatira zoyipa mwanjira yowonjezera kuchuluka kwa thupi.

    Yang'anani!Gululi la mankhwalawa lingathenso kutumikiridwa pophatikiza chithandizo cha Siofor ndi Glucofage, koma ndikofunikira kumuwunika wodwalayo momwe angathere kuti muchepetse zovuta.

    Mapiritsi a shuga - mndandanda wa mankhwala abwino kwambiri

    Mapiritsi a shuga amasankhidwa kutengera mtundu wamatenda, omwe amagawidwa m'mitundu iwiri: wodalira insulin komanso osafuna kuyambitsa insulin. Musanayambe chithandizo, werengani kagawidwe ka mankhwala ochepetsa shuga, kapangidwe ka zochita za gulu lililonse ndi contraindication kuti mugwiritse ntchito.

    Kumwa mapiritsi ndi gawo limodzi la moyo wa anthu odwala matenda ashuga.

    Mfundo za chithandizo cha matenda ashuga ndizosunga shuga pamlingo wa 4.0-5,5 mmol / L. Kuti muchite izi, kuwonjezera pa kutsatira zakudya zamafuta ochepa komanso kuchita masewera olimbitsa thupi pafupipafupi, ndikofunikira kumwa mankhwala oyenera.

    Mankhwala ochizira matenda a shuga amagawika m'magulu akulu akulu.

    Mankhwalawa odwala matenda ashuga ali ndi vuto la hypoglycemic chifukwa kuwonetsedwa kwa maselo a beta omwe ali ndi vuto lopanga insulin mu kapamba. Njira za gululi zimachepetsa chiwopsezo cha impso ntchito ndi kukula kwa matenda amtima.

    Maninil - mapiritsi otsika mtengo a odwala matenda ashuga

    Mndandanda wazomwe zimachokera ku sulfonylurea:

    Mankhwala a anthu odwala matenda ashuga a gululi ndi ofanana mu njira zochizira zotumphukira zotuluka za sulufayiti ndikuthandizira kupanga insulin. Kuchita kwawo kumatengera shuga.

    Novonorm ndiyofunikira pakupanga insulin

    Mndandanda wa meglitinides abwino:

    Pochiza matenda a shuga omwe amadalira insulin, meglitinides sagwiritsidwa ntchito.

    Mankhwala a gululi amateteza kutulutsa shuga kwa chiwindi komanso amathandizira kuti magazi ake azilowa mosavuta.

    Mankhwala osokoneza bongo wabwino

    Magulu amakulu othandiza kwambiri:

    Amadziwikanso ndi zotsatira zomwezo pakathupi monga biguanides. Kusiyana kwakukulu ndikokwera mtengo komanso mndandanda wosangalatsa wazotsatira zoyipa.

    Mankhwala okwera mtengo komanso ogwira mtima a shuga

    Izi zikuphatikiza:

    Thiazolidinediones alibe zotsatira zabwino mankhwalawa a mtundu 1 matenda a shuga.

    Mankhwala obwera mwatsopano omwe amathandizira kuwonjezera insulin ndikupanga shuga ku chiwindi.

    Galvus ndiyofunikira kuti amasule shuga ku chiwindi

    Mndandanda wa glyptins ogwira:

    Januvia kuti muchepetse magazi

    Othandizira amakono othandizira odwala matenda ashuga amalepheretsa kupanga enzyme yomwe imasungunula michere yambiri, potero imachepetsa kuthana kwa polysaccharides. Ma Inhibitors amadziwika ndi zovuta zochepa komanso amakhala otetezeka kwa thupi.

    Izi zikuphatikiza:

    Mankhwala omwe ali pamwambawa atha kumwa mankhwala osakanikirana ndi mankhwala a magulu ena ndi insulin.

    M'badwo waposachedwa wa mankhwala omwe amachepetsa shuga m'magazi.Mankhwala a gululi amachititsa impso kuti zimveke shuga ndi mkodzo panthawi yomwe kuchuluka kwa shuga m'magazi kumayambira 6 mpaka 8 mmol / l.

    Chida chofunikira chochepetsera shuga

    Mndandanda wa Glyphlosins Wothandiza:

    Mankhwala omwe amaphatikiza metformin ndi glyptins. Mndandanda wa njira zabwino kwambiri zophatikiza mitundu:

    Osamwa mankhwala osakanikirana mosafunikira - yesetsani kukonda mitundu yayikulu yakanthawi yayitali.

    Kuphatikiza kwa matenda ashuga

    Insulin kapena mapiritsi - ndibwino kwa matenda ashuga?

    Mankhwalawa amtundu wa shuga 1 a matenda a shuga, insulin imagwiritsidwa ntchito, mankhwalawa amtundu wa 2 a mawonekedwe osavuta amachokera pakumwa mankhwala kuti achulukitse shuga.

    Ubwino wa mapiritsi poyerekeza ndi jakisoni:

    • kugwiritsa ntchito mosavuta komanso posungira,
    • kusapeza bwino pakalandilidwa,
    • kuyang'anira kwachilengedwe kwachilengedwe.

    Ubwino wa jakisoni wa insulin ndi njira yothanirana mwachangu komanso kuthekera kosankha mtundu wabwino kwambiri wa insulin kwa wodwala.

    Jakisoni wa insulin amagwiritsidwa ntchito ndi odwala omwe ali ndi mtundu wa 2 shuga mellitus ngati mankhwala osokoneza bongo sawapereka bwino ndipo atatha kudya glucose amakwera mpaka 9 mmol / L.

    Jakisoni wa insulin amagwiritsidwa ntchito pokhapokha ngati mapiritsi sathandizira

    “Kwa zaka zitatu ndakhala ndikudwala matenda ashuga. Kuthetsa shuga m'magazi, kuphatikiza jakisoni wa insulin, ndimatenga mapiritsi a Metformin. Kwa ine, iyi ndi njira yabwino kwambiri yothandizira odwala matenda ashuga pamtengo wotsika mtengo. Mnzake amamwa mankhwalawa kuntchito kuti azichiritsa matenda a shuga a 2 ndipo ndiwosangalala. ”

    “Ndili ndi matenda ashuga a 2, omwe ndimawagwiritsa ntchito kwa zaka zingapo ndi mankhwala a Januvia, komanso a Glucobaya. Poyamba, mapiritsiwa andithandiza, koma posachedwa matenda anga adakulirakulira. Ndidasintha insulin - index ya shuga idatsikira ku 6 mmol / l. Ndimasangalalanso kudya ndikupita nawo kumasewera. ”

    "Malinga ndi zotsatira za mayeso, adotolo adawulula kuti ndili ndi shuga wambiri. Chithandizocho chinali monga zakudya, masewera, ndi Miglitol. Ndakhala ndikumwa mankhwalawa kwa miyezi iwiri tsopano - kuchuluka kwa shuga kwayamba kuchita bwino, thanzi langa lonse layamba. Mapiritsi abwino, koma okwera mtengo kwa ine. ”

    Kuphatikiza kwa zakudya zama carb ochepa komanso masewera olimbitsa thupi kumathandizira kukhazikika kwa shuga m'magazi a 2 a shuga.

    Pakakhala zovuta, perekani zomwe zimaphatikizidwa ndi mankhwala omwe amaphatikiza metformin - amalimbitsa shuga wambiri ndi zovuta zina. Mlingo komanso kuchuluka kwa jakisoni wa insulin kwa matenda amtundu wa 1 amawerengedwa ndi dokotala, kutengera mawonekedwe a wodwala.

    Voterani nkhaniyi

    (2 mitengo, pafupifupi 5,00 pa 5)

    Matenda a shuga ndi matenda a endocrine system ndipo thupi lonse limalumikizidwa ndi kuphwanya chilengedwe cha insulin komanso matenda obwera chifukwa cha carbohydrate metabolism. Matenda a shuga sangathe kuchira monga momwe mphuno imakhalira, kapena kuti, kutsegula m'mimba, ndikuchotsa mothandizidwa ndi mankhwala oyenera ma virus omwe ali m'mphuno kapena microflora ya pathogenic m'matumbo. Nthawi zambiri ndizosatheka kuchiritsa matenda a shuga omwe amadalira insulin mothandizidwa ndi mankhwala amakono, popeza madokotala sanaphunzire kutulutsa kapamba kapena kukula maselo a beta. Njira yokhayo yothetsera matenda a shuga 1 ndi ma insulin opangidwa, omwe mumafunikira kuti mulowetse thupi pafupipafupi kudzera jakisoni wothandizirana kapena wamisala. Palibe mapiritsi othandiza odwala matenda a shuga a mtundu woyamba, pali mankhwala othandiza, mwachitsanzo, Siofor kapena Glucofage, omwe amachepetsa kukana kwa maselo ku insulin.

    Makampani ogulitsa zamankhwala amayang'ana kwambiri pakupanga mankhwala a matenda a shuga a mtundu wachiwiri, omwe ali ndi maphunziro ochepa zolimbitsa thupi komanso amadziwika kwambiri.Mankhwala onse amatha kugawidwa ndi kapangidwe ka mankhwala, mfundo zoyenera kuchita ndi zolinga zomwe amagwiritsa ntchito mankhwalawa.

    Pali zovuta zitatu zamankhwala a shuga:

    • kukondoweza kwa maselo a beta a islets a Langerhans a kapamba kuti awonjezere insulin
    • kuchuluka kwa zamkati mwa minofu ndi mafuta maselo insulin,
    • Kuchepetsa mayamwidwe a shuga m'magazi, kapenanso kumatchingira m'matumbo.

    Tinene nthawi yomweyo: palibe imodzi mwazomwezi, kuphatikiza ngakhale mankhwala osokoneza bongo a m'badwo watsopano, omwe angatsimikizire zotsatirapo zabwino popanda mavuto. Njira za kagayidwe kazakudya zimapangika zovuta kwambiri ndipo zimatengera zinthu zambiri zomwe sizingaganiziridwe bwino. Wodwala ayenera kukonzekera kuti mankhwala azamankhwala azisankhidwa kwa miyezi yambiri, pogwiritsa ntchito njira zoyeserera komanso zolakwika. Akatswiri ena a matenda ashuga amatha kuseka nthabwala kuti kuli bwino kupaka insulin yachiwiri ya matenda a shuga inshuwaransi kwa odwala omwe ali ndi matenda ashuga, osazunzika chifukwa cha kupha ma cell a beta ndimankhwala osankhidwa bwino, kenaka jekeseni insulin mulimonse, koma m'malo mwake.

    Chifukwa chake, tiyeni tiyesere kuchoka kutali ndikuzindikira mankhwala amitundu yachiwiri ya shuga omwe amabweretsa zabwino zochepa mthupi.

    Malinga ndi akatswiri ambiri a endocrinologists, awa ndi mankhwala omwe amalepheretsa glucose m'matumbo ndikulepheretsa mamolekyulu ake kuti asalowe m'magazi. M'malo mwake, awa ndi mapiritsi a anthu omwe alibe mphamvu. Sangakane maswiti ndi zakudya zamtengo wapatali ndikusintha zakudya zamafuta ochepa, koma yesani kunyenga matupi awo. Amadya maswiti ndipo amamwa ndi mapiritsi osalola shuga kulowa m'magazi.

    Mwantchito, kapangidwe ka mankhwala ndi zoletsa za alpha-glucosidase, zomwe zimapangitsa chotchinga chachikulu pamaso pa mamolekyulu a shuga. Mankhwala akuluakulu amtunduwu ndi acarbose, amatengedwa katatu patsiku. Mtengo wa acarbose sukwera kwambiri, koma palibe chofunikira mu "chithandizo" chotere - munthu amawononga ndalama zogulitsa mankhwala osokoneza bongo m'malo mongogula imodzi kapena ina. China chilichonse, acarbose kumayambitsa kusokonezeka kwa m'mimba, zimatha kukulitsa chiwindi ndi kulephera kwa impso, sizingatengedwe panthawi yapakati komanso kuyamwa.

    Ubwino wachilengedwe wa acarbose ndi mawonekedwe ake ndikuti samayambitsa vuto lalikulu ku thanzi, samawopseza hypoglycemia (kuchepa kwambiri kwa shuga m'magazi), amathandizira anthu omwe CD-2 imachitika chifukwa cha zovuta zomwe zimachitika chifukwa cha zovuta za glucose (ndiye kuti, sizofunikira kusowa insulin, koma zakuti minofu ndi maselo amafuta sangafune kuyamwa ndipo shuga imakwera mosagwedezeka m'magazi).

    Kachiwiri pokhudzana ndi "kusakwanira" pakati pa mankhwala osokoneza bongo ndi omwe amachititsa kuti mitundu ina ya inshuwaransi ya Langerh ipititse kunja. Uku ndiye mtundu wa dope lomwe limapangitsa kuti zikondamoyo zizivala. Kwa nthawi yayitali, mankhwalawa amathandizadi, shuga ndi insulin kutulutsa, kumveketsa kwabwino komanso ngakhale kuchira kumabwera. Kwa odwala ena, izi sizingakhale zabodza, koma chikhululukiro chautali - shuga imatha kuyambiranso zaka. Koma chithandizo chikangoimitsidwa, shuga ayambanso kukula, ndipo ndizotheka kuti hyperglycemia isinthane ndi hypoglycemia. Ndi kuthekera kwakukulu, chilichonse chibwerera mwachizolowezi. Ndipo mwa odwala ena omwe ali ndi pancreas ovuta kwambiri, kumapeto, amangopanduka. Izi zili ndi khungu la pancreatitis pachimake - matenda oopsa chifukwa cha kuledzera kwambiri komanso kupweteka kwa matenda. Atayimitsa zizindikiro za pancreatitis wodwala, CD-1 mosakayikira iwonjezedwa ku CD-2, popeza maselo a beta sangapulumuka kutupa.

    Mankhwala omwe amalimbikitsa kaphatikizidwe ka insulin mu kapamba amaphatikizira magulu awiri a mankhwala:

    1. Derivatives of sulfonylureas - glycoslide, glycoside MB, glimepiride, glycidone, glipizide, glipizide GITS, glibenclamide.
    2. Meglitenides - repaglinide, nateglinide.

    Kuphatikiza pa kukomoka kosatheka kwa endocrine kapamba, mankhwalawa amawopseza malinga ndi hypoglycemia yosalamulirika komanso kukhumudwitsa m'mimba. Ikani zakudya zingapo. Madokotala ambiri amakonda kusunga mankhwalawa ngati achangu, m'malo mongogwiritsa ntchito maphunziro. Ndikofunikira kumwa meglitenides, omwe sanatchulidwe kwenikweni ngati ma cell a beta, komabe, mankhwalawa ali ndi mtengo wokwera kwambiri poyerekeza ndi zotumphukira za sulfonylurea. Onani tebulo la mankhwala ndi mankhwala.

    Mankhwala omwe amakhudzana ndi insulin kukokana ndi zimakhala kale ali ndi matenda a shuga am'badwo watsopano, amakhala othandiza komanso otetezeka, koma pamtengo wokwera. Gululi limaphatikizapo Biguanides (makamaka metformin) ndi thiazolidinediones (pioglitazone).

    Zinthu izi pafupifupi sizimayambitsa hypoglycemia yayikulu - shuga amachepetsa pang'onopang'ono ndipo mkati mwa "malire oyenera" - mankhwala osokoneza bongo amatha kubweretsa poizoni wa chakudya, koma osati kuphwanya kwa hypoglycemic com. Nthawi yomweyo, mankhwalawa amatha kubweretsa kusapeza kwa m'mimba, kutsekula m'mimba, kunenepa kwambiri. Kuphatikiza apo, zatsimikiziridwa kuti pioglitazone, ikagwiritsidwa ntchito pamaphunziro, imachulukitsa ngozi ya mtima, acidosis lactate (kawirikawiri), imayambitsa kutupa kwamiyendo ndikuwonjezera kusokonekera kwa mafupa. Monga mankhwala ena othandizira odwala matenda ashuga, mankhwalawa sayenera kuledzera chifukwa cha kulephera kwa chiwindi ndi impso, komanso kwa amayi oyembekezera komanso oyembekezera. Zilinso zopanda pake ngati chithandizo chadzidzidzi ndi kuwonjezeka kwa shuga - zovuta zamankhwala am'mgulu lino sizikuyamba kale kuposa maola atatu atakhazikitsidwa ndipo zimatenga nthawi yayitali.

    Mankhwala osokoneza bongo omwe ali ndi ntchito ya indirecttin ndi mankhwala aposachedwa a shuga omwe adakali m'mayesero azachipatala. Izi ndizabwino kwambiri, koma pakadali pano zinthu zotsika mtengo kwambiri zomwe zimaperekedwa ndi msika wazamankhwala. Mwa magwiridwe antchito, amafanana ndi sulfonylurea ndi meglitenides, ndiko kuti, amathandizira kapangidwe ka insulin zachilengedwe ndi maselo a beta a kapamba. Kusiyana kwakukulu ndikuti kukondoweza kuli kochenjera kwambiri, mahomoni ndipo sikogwirizana mwachindunji ndi kuchuluka kwa glucose ndi insulin m'magazi. Mankhwalawa amaphatikizapo njira yamkati yolumikizirana ya mitundu inayi yonse ya maselo opanga mahomoni, makamaka alpha ndi beta, omwe amapanga glucagon ndi insulin. Zotsatira zake, izi zimachitika mwanjira yachilengedwe ndipo minofu ya pancreatic siifa chifukwa chogwira ntchito mopitirira muyeso.

    Tsoka ilo, pali zovuta zingapo pano - chiopsezo cha kapamba, ma antibodies mawonekedwe a mankhwalawa, omwe angayambitse zovuta zosiyanasiyana. Mankhwala ambiri osadziwika amatha kubayidwa (komabe, odwala matenda ashuga, omwe mtsogolomo amakhala ndi syringe ya insulin, sangachite mantha ndi jakisoni).

    Mankhwala osokoneza bongo a gululi amatha kutengedwa pokhapokha pakuwunikira komanso kuyesedwa mosamala (makamaka pakulolera). Amayesedwa okwera mtengo kwambiri kuposa mankhwala onse a shuga. Pali ndemanga zochepa zokhudzana ndi mankhwalawa ndipo zimatsutsana. Ndizosatheka kuzigulira ndikugwiritsa ntchito popanda mankhwala a dokotala!

    Gululi limaphatikizapo zinthu zotsatirazi:

    • Maepeptidyl peptidase-4 (DPP-4) zoletsa - vildagliptin, saxagliptin, sitagliptin,
    • Glucagon-ngati peptide-1 receptor agonists: liraglutide, exenatide.

    Gulu lachiwiri la mankhwalawa lili ndi zabwino zingapo zowonjezera. Amateteza maselo a alpha ndi beta a kapamba, amathandizira kuchepetsa kuthamanga kwa magazi, kulakalaka kudya ndi thupi, zomwe ndizofunikira kwambiri kwa odwala ambiri omwe ali ndi matenda ashuga a 2.Ndi rectal mankhwala a shuga mellitus, kulimbikitsidwa kwa chakudya m'mimba mwake ndi mayamwidwe a glucose mwa makoma a matumbo ang'onoang'ono ndi otchulidwa. Koma agonists awa ndiokwera mtengo kwambiri malinga ndi malamulo aku Russia.

    Zoyeserera zikuchitika pakugwiritsa ntchito mankhwala a arectin ndi metformin. Lingaliro losatsimikizika lokhuza kuopsa kwakaphatikizidwe komweku sikunayambike, koma zikuwonekeratu kuti zotsatira zoyipa za metformin zimachepetsedwa. Pankhaniyi, wodwala amapeza mwayi wosungirako ndalama (kuchepetsedwa kumwa kwa mankhwala osapindulitsa a indirectin).

    Otsatirawa ndi gome la mankhwala onse amtundu wa 2 matenda ashuga malinga ndi momwe angachitire, dzina lapadziko lonse lapansi, chiwonetsero cha Russia, mlingo komanso kudya tsiku lililonse.

    Mankhwala Otsatira a Generation Amathandizira Kuchepetsa Thupi Komanso Kuchepetsa Kuwopsa Kwa Mtima Wanu

    Chaka cha 2016, chomwe chikuyandikira kutsiriza kwake komveka, chidabweretsa zinthu zosangalatsa. Panali ena omwe anapeza "mankhwala" osangalatsa opangira mankhwala omwe amapereka chiyembekezo kwa odwala omwe ali ndi matenda osachiritsika, makamaka matenda a shuga.

    Tsoka ilo, njira zosasintha zimachitika m'thupi la odwala matenda ashuga. Nthawi zambiri (90% ya milandu), kapamba sangatulutse timadzi tambiri m'magazi kapena thupi limalephera kugwiritsa ntchito bwino, chifukwa chomwe shuga mumagazi imakwera ndikuwonjezera shuga 2.

    Ndikukumbusani kuti insulini ndiyo njira yomwe imatsegulira njira ya glucose omwe amachokera mu chakudya kulowa m'magazi. Matenda a shuga a Type 2 amatha kuchitika zaka zilizonse, ndipo nthawi zambiri amakhala obisika kwa zaka zambiri. Malinga ndi ziwerengero, wodwala aliyense wachiwiri sazindikira kusintha kwakukulu komwe kumachitika mthupi lake, zomwe zimapangitsa kuti matendawa athe kudwala.

    Nthawi zambiri, mtundu woyamba wa matenda a shuga umanenedwa, pomwe ma cell a pancreatic nthawi zambiri amasiya kupanga insulin, kenako wodwalayo amafunikira kuperekera mahomoni kunja.

    Matenda a shuga a mitundu yonse 1 ndi mtundu 2, omwe adasiyidwa mwangozi, ndi owopsa kwambiri: masekondi 6 aliwonse amatenga moyo umodzi. Ndipo wakupha, monga lamulo, si hyperglycemia yokha, ndiye kuti, kuwonjezeka kwa shuga wamagazi, koma zotsatira zake zazitali.

    Chifukwa chake, matenda ashuga si owopsa monga matenda omwe "amayamba". Timalemba kwambiri.

    • Matenda a mtima, kuphatikiza matenda a mtima, omwe amachitika mwadzidzidzi omwe ndi masoka - kulowererapo kwa mtima ndi sitiroko.
    • Matenda A Impso, kapena Matenda A shuga, yomwe imayamba chifukwa cha kuwonongeka kwa ziwiya za impso. Mwa njira, kuwongolera bwino kwamwazi wamagazi kumachepetsa kwambiri kuphatikizika kwa vutoli.
    • Matenda a shuga - kuwonongeka kwamanjenje, kumayambitsa kugaya chakudya, kugona, kuchepa kapena ngakhale kuwonongeka kwa miyendo. Chifukwa cha kuchepa mphamvu, odwala sangathe kuwona kuvulala kwakung'ono, komwe kumakhala kukuwonekera chifukwa cha matenda opatsirana ndipo mwina kumatha kuduladula miyendo.
    • Matenda a shuga a retinopathy - kuwonongeka kwa maso, kudzetsa kuchepa kwa masomphenya mpaka kutsiriza khungu.

    Iliyonse mwa matenda amenewa imatha kubweretsa kupunduka kapena kufa, komabe, matendawa amawonedwa moyenera. Ndikudziwitsa kuti nthawi zambiri zimayambitsa kufa kwa odwala matenda ashuga. Kuwongolera kwa matenda oopsa, matenda a mtima, cholesterol ili pamlingo wofunika kubwezeretsedwanso wokwanira wa glycemia yokha.

    Ngakhale ndi machitidwe oyenera a zochitika - chithandizo choyenera, zakudya, ndi zina zotere - chiopsezo cha kufa ndi vuto la mtima kapena matenda a matenda ashuga ndiwokwera kwambiri kuposa anthu omwe alibe matenda a hyperglycemia.Komabe, mankhwala atsopano a hypoglycemic omwe cholinga chake ndi kuchiritsa matenda a shuga a 2 amatha kumapeto kwa makina othandizira ndikuwongolera kwambiri matendawo.

    Nthawi zambiri, mankhwalawa pochiza matenda osokoneza bongo omwe amadalira shuga amapatsidwa ngati mapiritsi amlomo. Lamulo losayankhulidwayu layamba kukumbukiridwa pakubwera kwa mankhwala omwe angathe kubayidwa omwe amachititsa kuti insulin itulutsidwe, monga liraglutide. Adapangidwa ndi asayansi ochokera ku kampani yotchuka kwambiri ku Danish yomwe imapanga mankhwala a shuga, Novo Nordisk. Mankhwala omwe amadziwika ndi dzina loti Saksenda (ku Russian Federation - Viktoza) adapezeka ku Europe chaka chatha. Adavomerezedwa ngati chithandizo cha matenda a shuga kwa omwe ali onenepa kwambiri okhala ndi cholozera cha misa (kutalika2 / cholemera) pamwamba pa 30.

    Chuma chabwino cha liraglutide, chomwe chimasiyanitsa ndi mankhwala ena ambiri a hypoglycemic, ndikutha kuchepetsa thupi - mawonekedwe osowa kwambiri kwa othandizira a hypoglycemic. Mankhwala a shuga nthawi zambiri amathandizira kulemera, ndipo izi ndizovuta kwambiri, chifukwa kunenepa kwambiri ndi chinthu chinanso chowonjezera. Kafukufuku akuwonetsa: pa chithandizo cha mankhwala a liraglutide, kulemera kwa odwala omwe ali ndi matenda a shuga amatsika ndi 9%, omwe angatengedwe ngati mtundu wamankhwala omwe amachepetsa shuga la magazi. Komabe, phindu lopindulitsa pa kulemera sindilo mwayi wokhawo wa liraglutide.

    Kafukufuku yemwe adachitika mu 2016 ndi odwala opitilira 9,000 omwe adatenga liraglutide pafupifupi zaka 4 adawonetsa kuti kulandira chithandizo ndi mankhwalawa sikuti kumathandizanso kuchuluka kwa shuga m'magazi, komanso kumachepetsa chiopsezo cha matenda amtima. Ogwira ntchito olimbikitsidwa a Novo Nordisk sanayime pamenepo ndipo mu 2016 anaperekanso mankhwala ena ochepetsa shuga - Semaglutid.

    Ndili m'mawa kwambiri kuyang'ana semaglutide m'mabuku a pharmacological: mankhwalawa akupitilizabe mayeso azachipatala, koma ngakhale pakadali pano "kugulitsa", adatha kuchita phokoso kwambiri mu sayansi. Woyimira watsopano wa Pareeral hypoglycemic mankhwala adadabwitsa aliyense ndi kuthekera kwawo kuchepetsa kwambiri zovuta za mtima ndi matenda ashuga. Malinga ndi kafukufuku yemwe wachitika ndi odwala opitilira 3,000, kulandira chithandizo chokhala ndi semaglutide kwa zaka ziwiri zokha kumachepetsa chiopsezo chokhala ndi myocardial infarction kapena 26%!

    Kuchepetsa mwayi wokhala ndi vuto lakuwala kwamtima, pansi pa lupanga la Damocles pomwe odwala matenda ashuga ambiri amakhala, pafupifupi kotala ndipamwamba lalikulu lomwe lingapulumutse miyoyo masauzande ambiri. Mwa njira, semaglutide, komanso liraglutide, amathandizidwa mosavuta, kuwonjezera apo, jekeseni imodzi pa sabata ndikokwanira kuti zithe. Zotsatira zochititsa chidwi ngati izi za ntchito yakufufuza za asayansi zimapangitsa kuyang'ana molimba mtima mtsogolo kwa mamiliyoni a odwala, kuwalimbikitsa ndi chidaliro: shuga si chiganizo.


    1. Dedov I.I., Kuraeva T. L., Peterkova V. A. Matenda a shuga a ana ndi achinyamata, GEOTAR-Media -, 2008. - 172 p.

    2. Nataliya, Aleksandrovna Lyubavina Katemera wa matenda otupa a m'mapapo komanso mtundu 2 shuga / Natalya Aleksandrovna Lyubavina, Galina Nikolaevna Varvarina und Viktor Vladimirovich Novikov. - M: LAP Lambert Academic Publishing, 2014 .-- 132 p.

    3. Vitaliy Kadzharyan und Natalya Kapshitar mtundu 2 matenda a shuga: njira zamakono zamankhwala, LAP Lambert Academic Publishing - M., 2015. - 104 p.

    Ndiloleni ndidziwitse. Dzina langa ndi Elena. Ndakhala ndikugwira ntchito ya endocrinologist kwa zaka zoposa 10. Ndikukhulupirira kuti pakadali pano ndili katswiri pantchito yanga ndipo ndikufuna kuthandiza alendo onse omwe amapezeka pamalowo kuti athetse zovuta osati ntchito. Zinthu zonse za tsambalo amazisonkhanitsa ndikuzikonza mosamala kuti athe kufotokoza zambiri zofunikira. Musanagwiritse ntchito zomwe zikufotokozedwa pa webusaitiyi, kufunsana ndi akatswiri ndizofunikira nthawi zonse.

    Kusiya Ndemanga Yanu