Langerin: ndemanga zamankhwala, mtengo, malangizo

mankhwala

dyucha recovina: metformine

Langerin 500: Piritsi limodzi la metformin hydrochloride 500 mg, lofanana 390 mg metformin,

Langerin 850: Piritsi limodzi la methyl metformin hydrochloride 850 mg, lofanana ndi 662.9 mg metformin,

Langerin 1000: Piritsi limodzi la metformin hydrochloride 1000 mg, lofanana ndi 780 mg metformin,

mawu owonjezera: sodium wowuma, madzi 40, silicic acid madzi osokoneza, chimanga wowuma, magnesium stearate, balere Sepifilm bilium 752 (hypromellose, macrogol-2000-monstearate, titanium dioxide), macrogol.

Fomu la Likarska. Mapiritsi, mu chipolopolo.

Gulu la Pharmacotherapeutic. Kuvutikira kwa antidiabetes. Hypocliticemia wamlomo. Khodi ya PBX A10BA02.

- Insulonezonezhniy Tsukrov matenda amtundu II, ngati riven zucchar m'magazi si mokwanira pidtrimuvati ochepera dyutoy, ufulu wakuthupi ndi kutsikira kwa masi ty,

- kuphatikiza ndi insulin - vuto la matenda ashuga a m'matumbo a I, ndizotheka kutembenuka pang'ono, komwe kumachitika ndi kuthana ndi insulin.

A shuga a keto acidosis, matenda a shuga komanso chikomokere,

kusokonekera ntchito nirok,

Gostrіi zhvoryuvannya, scho igry іz іz rіzіkom chitukuko cha kutayika kwa ntchito nirok: kuchepa kwa magazi (pakachitika matenda am'mimba, magazi), ngozi, іnfektsііnі zhvoryuvannya, kukhala oletsedwa, sepsis,

Zowonekera zazamankhwala zamatenda a gostrich komanso zhoryvoryvan, omwe angapangitse kukula kwa minofu hypoxia (matenda a mtima ndi dichromic insuffence, gostrii myocardial infarction,

opaleshoni yayikulu ndikuvulaza (ngati kuli kotheka, anachitapo zochizira)

ntchito yosweka,

mowa woledzera, gostre otruєnny mowa,

chidwi ndi metformin kapena zigawo za mankhwala,

ukazi ndi chaka cha bere,

lactic acidosis (kuphatikizapo mbiri),

dotrimannya gіpokalorіyno dієti (ochepera іzh 1000 cal / ext),

mwana amafika pathanthwe 10.

Sitikulimbikitsidwa kuti tisaumitse Langerin kwa anthu azaka zopitilira 60, omwe amatha kukhala ndi thupi lolimba, ndikofunikira kuti apange lactic acidosis mwa iwo.

Sposib zososuvannya kuti dozi.

Ana oposa 10 thanthwe

Chithandizo cha Mono ndikuphatikizidwa ndi inshuwaransi

Pochatkova nyumba yosungirakoє 1 piritsi 500 mg kapena 850 mg 1 nthawi pa dob. Pambuyo masiku 10-15, mlingo wa corigovati wotsatira umasonyezedwa mpaka magazi a shuga. Povіlnee pіdvishchenny dosuvannya moget kuchepetsa pafupipafupi zotsatira zoyipa kumbali yamatumbo.

Mlingo wapamwamba kwambiri wa dobova ndi 2000 mg (rosodiene wa 2-3 priyomi).

Chithandizo cha Mono komanso kuphatikiza ndimankhwala oteteza pakamwa

Mlingo wa Pochatkova kupita ku malo osungira a Langerin 500 mg 2-3 kawiri pa doba kapena 850 mg 2 kawiri pa doba. Pambuyo masiku 10-15, mlingo wa corigovati wotsatira umasonyezedwa mpaka magazi a shuga. Mlingo wapamwamba ungachepetse kuchuluka kwa zoyipa kuchokera kumbali yamatumbo.

Mlingo wapamwamba kwambiri wa dobova ndi 3000 mg.

Panthawi ya kusintha kwa mankhwala oyambitsa kamwa wodwala matenda amkamwa, imwani mankhwalawa nthawi ina ndikakonza ndikuperekera zakudya zomwe zikunenedweratu ndi mlingo wa metformin.

Kuphatikiza ndi insulin

Kuti mukwaniritse kuwongolera kwakanthawi kwa glikemії, ndizotheka kukonza metformin ndi wophatikiza wophatikiza. Zvichain pochatkova mlingo Langerin yosungirako yosungirako 500 mu 850 mg katatu pa mlingo, pa ola lomwelo nditha kumwa mankhwala a insulin ndisanafike magazi a shuga.

Gawo La Dziko

Vrakhovuchi kuthekera kuchepetsa kuchuluka kwa ntchito mwa odwala omwe ali ndi mlingo wochepa wa metformin akuwonetsedwa kuti ndi olondola mpaka ntchito ya faifi tambala. Ndikofunikira nthawi zonse kuwunikiranso ntchito ya nirok.

Triviality chithandizo akuwonetsedwa ndi kuzimitsa pang'ono ndi kusokonezeka kwa kulanda.

Tenga piritsi, itenge, itenge, kudikirira tsiku, kapena kumwa.

Pobichny zimachitika.Zowonongeka kumbali yamtundu wa slag-m'mimba: nseru, mabuluu, "chitsulo" chodumphira pakamwa, kudzimbidwa, kusasangalala, kugona tulo, kutsegula m'mimba, kupweteka m'mimba. Zizindikiro zake zimakhazikika makamaka pa chitsamba chamadzi, ndipo monga lamulo, amadzidziwa okha. Zizindikiro zimasintha ndi antacid, atopic atropine, ndi spasmolytic. Kuti mutulutsire Gahena pazotsatira zoyipa izi, tikulimbikitsidwa kuti muyambitse mankhwalawa kwa theka la ola, kapena osachepera 2-3 pakawonjezera. Yakshcho dyspeptic zizindikiro __, lіkuvannya mankhwala slіd priniti.

Zowonongeka kumbali obmіnu rechovin: lactic acid dyatez (Ndidzafunika vіdmіni lіkuvannya), wokhala ndi zazing'ono lіkuvannі - gіpovіtamіnoz V₁₂ (adagwa nthawi yonseyi).

Zowonongeka mbali ya magazi: mu okremich vipadakh - anemia ndi megaloblastic.

Zotsatira zoyipa: Pitani ku shkіrі.

Bongo. Ndi metastasis metformin pa mlingo wa 85 g, kukula kwa hypoglycemia sikulephera. Ale mu tsyuyu vipadka mizere lactic acidosis. Zizindikiro zoyambirira za lactic acidosis ndi "nseru, magazi, kutsegula m'mimba, kutentha, matumbo, m'mimba ndi amayi, m'malere munthu amatha kusokonezeka, kuwononga mpweya komanso nthabwala.

Likuvannya: kuwoneka mu vipadok wokhala ndi chizindikiro cha lactic acidosis ya mankhwalawa, muyenera kuyimitsa, kukhala ndi chipatala chokwanira, kuwonetsa kuchuluka kwa mankhwalawa, mwachindunji matenda. Naybilsh m'njira yothandiza ndi kukhazikitsa organic lactate ndi kukonzekera препара hemodialysis. Komanso khalani ndi zisonyezo lіkuvannya.

Zastosuvannya pa nthawi vaginosti chaka chamabele. Ngati mwakonza vaginosti, komanso kukhala ndi vipad, vaginostnosti kumbuyo kwa kumwa mankhwalawa, muyenera kukumbukira ndikuwonetsa insulin. Amayi ndi ana akhanda amasamalidwa kwambiri.

Zina zastosuvannya. Monga lamulo, wodwalayo anali ndi magazi, kupweteka m'mimba, kupweteka m'mimba, kufooka kumakhala ndi mphamvu komanso kulimba sikumata, ndiye kuti ndidamkankha mwamphamvu. Popeza zizindikirozi, mutha kuyang'ana bwino khutu la lactic acidosis.

Zaka 48 chaka cha 48 chisanafike, pambuyo pa X-ray kusiyana radiography (orography, vennum yamkati) itachitika, mankhwala otsatirawa ayenera kumwedwa.

Momwemonso metforminom idadutsa zaka 48 isanachitike kuchita hirurgicheskoe kupatsirana mankhwala oletsa kubwezeretsa komanso kutsegulanso osapitilira zaka 48 pambuyo pake ntchito ya hirurgicheskoy.

Langerin si chakumwa chabwino kwambiri cha mowa.

Thanzi lofunika kuti liwonjezeke kuthamanga mukamagwiritsa ntchito magalimoto onse mwanjira iliyonse. Langerin sindiye chifukwa cha hypoglycaemia, ndicho chifukwa chokhazikika cha masomphenyawo. Ngati mukukhutira ndi zochitika zofunikira kwambiri (insulin, anti-diabetes, bora sulfonylase ndi kusinthasintha), mutha kupita patsogolo ku metforminosis. Amakulolani kuti musunthe dyalnost molakwika, monga kuthamanga kwambiri kwamalingaliro ndi thupi, kuvomereza lingaliro mwachangu (mwachitsanzo, kusamalira zovuta zamayendedwe, kupereka magalimoto ndi makina, ndiye gwiritsani ntchito).

Kulumikizana ndi ma tabu ofunikira kwambiri ndikuwona kusinthana. Palibe zonena usiku umodzi primenom danazolu za giperglіkemіchno dії yotsalira. Ngati mukufuna kupereka danazol ndi kubwezeretsanso mlingo, imwani mlingo woyenera wa mankhwalawo mothandizidwa ndi kutsekemera kwina.

Kumwa mowa ndi mowa kumathandizira kukhazikitsa lactic acidosis pa ola limodzi la zakumwa zoledzeretsa, makamaka pamavuto a njala, koma kuwonjezera pa kuchepa kwa kalori yocheperako, komanso ngati pali zovuta. Під ola limodzi kwa priyomuyu mankhwala slіd unikati priyyu mowa і lіkarskikh zasobіv, scho kubwezera mowa.

Kuphatikiza komwe kumafunikira chisamaliro chapadera

Chlorpromazine: mukumwa Mlingo waukulu (100 mg pa dob), ndikutenga glіkemіy, ndikuchepetsa insulin. Pankhani ya antipsychotic ndi mankhwala, nditenga mitundu yonse yotsalira ndikuwongolera gulu lonselo.

Glucocorticosteroid (GCS) mwadongosolo komanso modekha kulekerera glucose, kuwonjezera glutemia, ndi kupewa ketosis. Ngati muli ndi GCS ndipo ndikulemba kumwa mlingo wonsewo, konzani muyezo ndi kuyang'anira kwa GLI.

Zopatsa: Kulandila kwa ola limodzi lokhazikika kungayambitse kukula kwa lactic acidosis kudzera mukusowa kwa maliru nirkov.

Yodvmіsnі radiocontrast malankhulidwe: Zotsatira za radiogic zamatenda ofiira a x-ray zitha kuphatikizidwa ndi lactic acidosis mwa anthu odwala matenda ashuga kapenanso kuperewera kwa ntchito. Sungani mankhwalawo atatha zaka 48 m'mbuyomu ndipo simukumva kudwala osakwanitsa zaka 48 pambuyo pa kuyezetsa magazi kwa chaka cham'mbuyomu ku radiopaque rechinov.

Woikidwa pa viglyad ін'tєєкцій b₂Muthana: Limbikitsani Kutanthauzira Malimbikitso a Kulimbikitsa b₂-kalandila. Pa tsyomu vipad potroben ulamuliro glikemії. Ngati ndi kotheka, nthawi yoikidwiratu ndiyofunika.

Ndi mankhwala osankhidwa nthawi imodzi ndi sulfonylsechovini womaliza, insulin, acarbozoy, salicylates, mutha kulimbikitsa.

Atsogoleri azachipatala.Mankhwala. Metformin - yayikulu yomwe ili ndi anti-hyperglycemic effect, zomwe zikutanthauza kuti ndimachepetsa hyperglycemia, sizikutsogolera kukula kwa hyperglycemic. Sindimalimbikitsa kubisalira kwa insulin ndipo sindimayambitsa mabvuto azabwino mwa anthu athanzi.

Metformin pidvishchu kudziwa zotumphukira zolandilira insulin ndikugwiritsa ntchito shuga ndi clitins. Upovlennyu gluconeogeneis mu chiwindi. Ndikupukuta chakudya chonse m'matumbo. Kugwirizanitsa zabwino pa kagayidwe ka lipids: Nditha kutsitsa cholesterol, komanso kutsika kwa cholesterol ndi ma glycerides atatu.

Pharmacokinetics. Pamene metastasis yamkati imachotsedwa m'matumbo, nthawi zambiri, ndowe, 20-30% ya mankhwalawa imawoneka. Mtheradi bioavailability wokhala 50% mpaka 60%. Ndi kuvomereza kamodzi kwa zotsekemera, metformin imachepetsedwa ndikuwathetsa.

Metformin shvidko rozpodilyaetsya mu minofu, ndikothandiza kuti musatenge nawo mapuloteni a plasmas. Metformin metabolism ndiosakhazikika pamtendere ndikutsogolera nirka.

Metirin wa Nirkovy klirens amakhala> 400 ml / hv. Chifukwa cha iwo omwe akufuna kupezerapo mwayi pa kalabu, kalabu yopanga zojambula bwino komanso zinsinsi za tubular. Kintseviy nthawi pa pіvzhitty pіslya mkamwa makonzedwe osungira mu metformіnu pafupifupi 6.5 chaka.

Ndi nirkov funktsion nirkov klirens metformіnu yochepetsedwa molingana ndi klirensu yatsopano ya wopangayo. Nthawi yoyenda idzakumana, mulingo wa metformin mu plasma zrosta.

Mphamvu yakuthupi ndi yaukadaulo:

Langerin 500: bіlі roundі, mapiritsi a biconvex, mkati mwa chipolopolo,

Langerin 850: mapiritsi a bilium oval, mkati mwa chigobacho, ali ndi chiopsezo kuchokera mbali imodzi,

Langerin 1000: bilі oval mapiritsi, mkati mwa chipolopolo, chiopsezo choopsa kuchokera mbali zonse ziwiri.

Matalikidwe 3 miyala.

Sambani zberigannya. Sindifunikira zberigannya zapadera. Zberigati kuchokera kwa ana.

Kulongedza. 10 mapiritsi a chithuza, 3 kwa 6 aliyense, kapena 9 mapiritsi 9 a chithuza.

Gulu vіdpusku. Chinsinsi.

Virobnik. PA "Zentiva".

Місцезнаходження. Нітрянська, 100, 920 27 Hlohovec, Slovak Republic.

Katundu wama mankhwala ndi zizindikiro zogwiritsira ntchito

Kupanga kwa gawo lalikulu la mankhwala kumalumikizidwa ndi mphamvu yake yoletsa njira za gluconeogeneis, komanso njira za kaphatikizidwe wamafuta acids amafuta ndi oxidation wamafuta. Woimira kalasi la Biguanide samakhudza kuchuluka kwa insulin yomwe imatulutsidwa m'magazi, koma amasintha ma pharmacodynamics awo mwa kuchepetsa kuchuluka kwa insulini kumasulidwa ndikuwonjezera kuchuluka kwa insulini kuti proinsulin.

Chofunikira pakuwoneka kwa mapiritsi oterewa ndi kukondoweza kwa glucose omwe amapezeka m'maselo a minofu.

Chizindikiro chachikulu chogwiritsira ntchito mankhwalawa ndikutukuka kwa matenda a shuga omwe amadalira insulin mwa munthu, makamaka ndi kusakwanira kwa zakudya zomwe amatsata.

Mankhwala enieni a Langerin ndi awa:

• amachepetsa kuchuluka kwa hemoglobinꓼ ya glycated
• saiziwalitsa kukana kwa insulini m'maselo kupita ku ma insulin a insulin
• zimakhudza kutengera kwa mawonekedwe a lipid a plasmaꓼ
• amachepetsa cholesterolꓼ yoyipa

Kuphatikiza apo, kugwiritsa ntchito mankhwalawa kumatha kulimbitsa thupi.

Malangizo ogwiritsira ntchito mapiritsi

Mankhwala Langerin amapezeka mu mawonekedwe a mapiritsi okhala ndi tulo.

Mapiritsiwo amadzaza ndi thumba la pulasitiki, lomwe limasindikizidwa ndi zojambulazo za aluminiyamu.

Mapaketi amaikidwa pabokosi la makatoni pamodzi ndi malangizo ogwiritsira ntchito mankhwalawa.

Kutengera kuchuluka kwa mankhwalawa omwe agwiritsidwa ntchito, mankhwalawa atha kugulidwa ndi mlingo wa:

1. Ma milligram 500.
2. 850 mamililita.
3. Gramu imodzi yogwira ntchito.

Njira yothetsera mapiritsiwa imakhala pakumwa, panthawi yakudya kapena itatha. Dotoloyo akupereka mankhwala kwa wodwala aliyense payekha malinga ndi kuopsa kwa matendawa. Komanso, katswiri wazachipatala amazindikira kuchuluka kwa mankhwalawa tsiku lililonse masana.

Langerin-malangizo angagwiritsidwe ntchito amalimbikitsa kuyambitsa njira yochiritsira yochepetsera ndi osachepera 500 mg a yogwira ntchito. Kuchuluka kwa Mlingo wa mankhwalawa masana kungakhale kwa mmodzi kapena atatu. Pang'onopang'ono, mlingo ungathe kuwonjezeka mpaka 850 mg wa chinthu chogwira tsiku lonse (kamodzi kawiri pa tsiku). Dokotala wothandizirayo amawunikira wodwalayo ndipo osapitirira kamodzi pa sabata, amasintha mlingo wa mankhwalawo.

Mankhwalawa adapangidwanso zochizira matendawa ana opitirira zaka khumi. Monotherapy iyenera kuyamba ndi mlingo wa 500 mg yogwira ntchito kamodzi kapena kawiri pa tsiku. Pakapita kanthawi, kuwonjezeka kwapang'onopang'ono kwa mlingo wa mankhwalawa amaloledwa, koma osaposa magalamu awiri patsiku, omwe amagawidwa pawiri kapena katatu.

Nthawi zambiri, kusintha kwa muyezo wa mankhwalawa kumachitika pakatha masiku khumi mpaka khumi ndi asanu potengera zotsatira za kuyezetsa magazi pamlingo wama glucose.

Nthawi zina, kuphika piritsi ndi gawo limodzi la mankhwala ophatikiza ndi jakisoni wa insulin.

Tiyenera kudziwa kuti munthawi yomweyo mankhwala a Langerin omwe ali ndi insulin, zotumphukira za sulfonylurea, acarbose, kapena ACE inhibitors amadziwika kuti amawonjezera mphamvu ya hypoglycemic ya mankhwalawa.

Nthawi zina, dokotala yemwe amapezekapo akhoza kusintha kugwiritsa ntchito Langerin ndi mapiritsi ofanana. Masiku ano, pali mitundu yambiri ya mankhwala, omwe amagwiritsidwa ntchito kwambiri ndi metformin.

Mtengo wa mankhwala a analog ukhoza kusiyana kwambiri, kutengera kampani yopanga mankhwala.

Kodi zotsutsana ndizogwiritsa ntchito chiyani?

Mlingo wosankhidwa molakwika kapena kusatsatira malangizo a dokotala kungakupangitseni kuoneka ngati musanamwe mankhwala.

Kuphatikiza apo, pali zochitika zina komwe kugwiritsa ntchito mankhwala ozungulira metformin ndikoletsedwa.

Malangizo ogwiritsira ntchito mankhwalawa akuwonetsa mndandanda wazotsatira zazikulu.

Milandu yayikulu pakugwiritsa ntchito mapiritsi a Langerin ndi awa:

• kuwonongeka kwakukulu kwa chiwindi kapena impso, kusowa kwawoꓼ
• uchidakwa, kuphatikiza pamakhalidwe oyipaꓼ
• mtima kapena kupuma kwamphamvuꓼ
• pachimake myocardial infarctionꓼ
• Mkhalidwe wodwala matenda ashuga kapena kholo
• chitukuko cha matenda ashuga phaziꓼ
• pamaso pa tsankho la munthu ndi metformin komanso kusintha kwa zinthu zina zosagwirizana ndi gawoꓼ
• kukhalapo kwa matenda opatsirana infectious
• kusala ndi matenda ashuga kapena kutsatira zakudya zomwe zakudya zake za tsiku ndi tsiku siziposa kilocaloriesꓼ
• Opaleshoni isanachitike komanso itachitika
• ndimavulala azambiri recent
• isanachitike komanso itatha diagnostic omwe amagwiritsa ntchito radio isotropes ya iodineꓼ
• ketoacidosis ndi lactic acidosis.

Kuphatikiza apo, azimayi sayenera kumwa mankhwalawa panthawi yoyembekezera

Kupezeka kwa zoyipa kumatha kudziwonekera mwa mbali zosiyanasiyana za thupi ndi machitidwe a thupi - m'mimba thirakiti, kagayidwe kazinthu, mtima dongosolo, khungu. Zoyipa zazikulu zomwe zimachitika chifukwa ch kumwa mankhwalawa ndi:

1. Kukweza mwachangu. Nthawi zina mseru umapezeka mu mtundu 2 shuga. Khansa ya m'magazi ikhoza kusinthidwa ndi kusanza.
2. Mtundu wopweteka wam'mimba.
3. Maonekedwe akununkhira wachitsulo pamkamwa wamkamwa.
4. Hematopoiesis ndi heestasis.
5. Megaloblastic anemia.
6. Kutsitsa shuga m'magazi pansi pazovomerezeka - hypoglycemia.
7. Maonekedwe ofooka m'thupi.
8. Kugona.
9. Hypotension.
10. Matenda opatsirana.
11. Maonekedwe a dermatitis kapena totupa pakhungu.

Chenjezo liyenera kumwedwa mukamamwa Langerin ndi mankhwala ena. Kugwiritsa ntchito pamodzi mapiritsi ndi cymeditine kumawonjezera chiopsezo cha lactic acidosis. Kuphatikiza kwa Langerin ndi ma loopture otentha kumatha kukhala ndi zotsatira zomwezo. Pankhaniyi, kuwonjezera pakuwonetsedwa kwa lactic acidosis, chiwonetsero cha kulephera kwa impso chitha kuonedwa.

Kugwiritsa ntchito mankhwalawa, ndikofunikira kuyang'anira momwe impso zimagwirira ntchito ndikuwonetsa kuchuluka kwa lactate mu plasma osachepera kawiri pachaka.

Zambiri zokhudzana ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda a shuga zimaperekedwa mu kanema munkhaniyi.

Dzinalo Lopanda Padziko Lonse

Dzinalo lapadziko lonse limagwirizana ndi dzina lantchito - Metformin (metformin).

Langerin amagwiritsidwa ntchito kuchepetsa magazi.

Nambala ya ATX ndi nambala ya A10BA02.

Kutulutsa mafomu ndi kapangidwe kake

Mankhwalawa amapezeka mwa mawonekedwe a mapiritsi a pakamwa. Mitundu yotere imasiyanitsidwa - yokutidwa, nthawi yayitali, yophimbidwa ndi nembira yamafilimu, yophimba enteric.

Pulogalamu yofunika kwambiri ndi metformin hydrochloride. Omwe amapezekapo: wowuma chimanga, magnesium stearate, macrogol 6000, anhydrous colloidal silicon dioxide, povidone 40, titanium dioxide, starch sodium glycolate, hypromellose, monstearate-2000-macrogol.

Pharmacokinetics

Mukamamwa mankhwalawo mkati, mankhwalawo amamwa kwathunthu thirakiti, pomwe gawo limodzi limatulutsidwa kuchokera m'thupi ndi ndowe. Kuchuluka kwazinthu kumatha kufikira maola awiri ndi theka. M'magazi, mankhwalawa sakhala ndi ma protein; mu ma cytoplasm a maselo ofiira, ma cell omwe amathandizira amadziunjikira monga ma granules.

Mpaka gawo limodzi mwa magawo atatu a mankhwalawa amachotsedwa m'thupi ndi ndowe.

Contraindication

Metformin ndi yoletsedwa kugwiritsidwa ntchito pazinthu zotere:

• Hypersensitivity zigawo zikuluzikulu,
• ndi kuwonongeka kwambiri kwa impso ndi chiwindi.
• ndi chidakwa,
• ndi matenda a matenda opatsirana komanso mtima
• mitundu yosiyanasiyana ya acidosis,
• Mimba ndi kuyamwa
• kugwiritsa ntchito ayodini
• ndi njala komanso kusowa kwamadzi.

Momwe mungatenge Langerin

Mankhwalawa amatengedwa ndikuwonetsetsa kuchuluka kwa shuga m'magazi, omwe wodwalayo amayenera kuyeza kangapo patsiku: m'mawa, mutatha kudya chilichonse, madzulo asanagone.

Kulandila - pakamwa mukudya chakudya kapena mukatha. Mlingo woyambirira umachokera ku 500 mg mpaka 850 2 kapena katatu pa tsiku. Pambuyo pa masabata awiri, mlingo uyenera kusinthidwa malinga ndi zotsatira za kusanthula kwa glycemic.

Mlingo waukulu kwambiri sungadutse 3000 mg, umagawidwa katatu.

Kwa ana atatha zaka 10, mlingo ndi 500-850 mg patsiku 1 nthawi imodzi. Mlingo wapamwamba ndi 2000 mg, wogawidwa ndi 2-3.

Ndi matenda ashuga

Malangizo ogwiritsira ntchito amagawa mankhwalawa kukhala monotherapy komanso kuphatikizana ndi insulin. Mlingo woyambirira ndi 500-850 mg kawiri tsiku lililonse kapena mutadya. Pambuyo pa milungu iwiri, kusintha kwa mlingo kumachitika malinga ndi zotsatira za kuwongolera shuga. Nthawi yonseyi, wodwala ayenera kukhala ndi mbiri ya glycemic. Mlingo wololedwa wambiri ndi 3 g, womwe umagawidwa 3 Mlingo.

Mu shuga mellitus, malangizo ogwiritsira ntchito mankhwalawa amagawa mankhwalawo kukhala monotherapy komanso kuphatikiza ndi insulin.

Zotsatira zoyipa za Langerin

Zochitika zoyipa kuchokera ku ziwalo ndi machitidwe osiyanasiyana zimatha kukhazikika.

1. Khungu: kuzimiririka, ming'oma.
2. Zokhudza hepatobiliary dongosolo: chiwindi, chiwindi ntchito.
3. Zizindikiro zamitsempha: zovuta zamakomedwe.
4. Kuchokera pamimba: kukhudzidwa ndi mseru, kusanza, kutsegula m'mimba, kusowa kwa chakudya, kupweteka kwam'mimba, kutulutsa magazi, kusowa kwazitsulo pakamwa.
5. Nthawi zambiri pamakhala kusintha m'magazi - megaloblastic anemia, kuchepa kwa vitamini B12.

Mawonetseredwe azachipatala amadzisowa pawokha atasiya mankhwala. Nthawi zina, mankhwala achiwonetsero amafunikira.

Malangizo apadera

Amakhala ndi kusintha mlingo (nthawi zambiri piritsi limagawidwa m'magulu awiri) ndikuphunzira kuthekera kwa kusankha kwake m'magulu osiyanasiyana a anthu.

Gwiritsani ntchito mu ukalamba

Mwa anthu okalamba, magwiridwe antchito a machitidwe ambiri (impso, vuto la mtima) nthawi zambiri amavutika, chifukwa chake ambiri odwala amagwiritsa ntchito mankhwala kuwasamalira. Ndipo ngati pali kusagwirizana kwa mankhwalawa, ndiye kuti muyenera kusiyira Langerin kapena kusintha mlingo wake (ngati zingafunike, gawanani piritsi ili pakati, tengani imodzi).

Kupatsa ana ntchito

Mankhwalawa amalembera ana opitirira zaka khumi. Ali aang'ono, mankhwala ena amasankhidwa. Kuyesedwa kwa mankhwalawa muubwana sikunachitike, kotero palibe chidziwitso pazakukhudzidwa kwake, kukula ndi kutha kwa ana, makamaka pakugwiritsa ntchito kwa nthawi yayitali. Chifukwa chake, iyenera kugwiritsidwa ntchito mosamala mu gulu la zaka 10-12.

Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere

Pokonzekera kutenga pakati, muyenera kusiya kumwa Langerin ndikudziwitsa dokotala za izi. Adziwitsanso kuchuluka kwa insulini, yomwe idzafunika kugwiritsidwa ntchito nthawi yonse ya bere. Zotsatira za metformin pa mwana wosabadwayo zimatchulidwa kuti B.

Pokonzekera kutenga pakati, muyenera kusiya kumwa Langerin ndikudziwitsa dokotala za izi.

Kafukufuku pa nthawi yoyamwitsa sanachitike, palibe chidziwitso pakulowerera kwa metabolites mu mkaka, chifukwa chake, panthawi ya mkaka wa m`mawere, muyenera kusiya mankhwalawo.

Mankhwala osokoneza bongo a langerin

Mukamagwiritsa ntchito mlingo wokwanira kuposa momwe muyenera, zimakhazikika: lactic acidosis, kumva kuuma pakamwa, mucous membrane, khungu, minofu ndi kupweteka pachifuwa, kupumira mwachangu, kusokonezeka kwa tulo, zizindikiro za kukomoka, kusokonezeka kwa mitsempha, kupweteka kwam'mimba, kusanza, kusokonekera kwa mtima, oliguria, ICE. Kuphatikiza apo, zinthu za hypoglycemic sizikukula. Palibe chithandizo chamankhwala. Monga mankhwala, dialysis ndi hemodialysis zimagwiritsidwa ntchito moyenera, ndipo chithandizo chamankhwala chimachitidwanso. Kuchotsera mankhwala mwachangu ndikofunikira.

Kuphatikiza kophatikizidwa

Ngati kuli kofunikira kuchita njira yomwe mankhwala okhala ndi ayodini azigwiritsidwa ntchito, muyenera kusiya kumwa Langerin m'masiku awiri. Ndipo kuyambiranso kwa mankhwalawa ndikotheka patatha masiku awiri atatha kafukufukuyu, izi zisanachitike, kuyesedwa kuyenera kuchitidwa kuti muwone momwe matendawa amathandizira. Kupanda kutero, kukula kwa aimpso kulephera ndikotheka, chiopsezo cha lactic acidosis.

Glformin ikhoza kukhala chosakanizira cha mankhwalawo.

Mankhwala Danazol sagwiritsidwa ntchito pochiza Langerin. Izi zili ndi shuga wambiri, acidosis, komanso chiwopsezo chokhala ndi chikomokere. Chifukwa chake, glycemia iyenera kuyang'aniridwa.

Kuphatikiza komwe kumafunikira kusamala

Mosamala kwambiri, mankhwalawa amayenera kugwiritsidwa ntchito limodzi ndi glucocorticosteroids a systemic kapena a m'deralo, ma inhibitors a ACE, diuretics, beta-2-sympathomimetics - magulu awa a mankhwala amatha kuchepetsa shuga m'magazi. Chifukwa chake, muyenera kuchenjeza wodwala za izi, komanso kusintha mlingo wa Langerin.

Chlorpromazine ndi antipsychotic alinso mankhwala, mogwirizana ndi momwe mankhwalawa amagwiritsidwa ntchito popanga mankhwala a metformin.

Kuyenderana ndi mowa

Sizigwirizana ndi mowa. Akaphatikizidwa ndi ethanol, chiopsezo chokhala ndi boma lactic acidotic chimakulirakulira, makamaka ndi mavuto ndi chiwindi (kulephera kwa chiwindi) kapena kuperewera kwa chakudya choyenera.

Malonda a Langerin ndi mankhwalawa:

• Glyformin
• Kutalika kwa Gliformin,
• Chikwanje,
• Metformin
• Metfogamma,
• Fomu,
• Siofor mu Mlingo wosiyanasiyana (1000, 800, 500),
• Vero-Metformin,
• Glycomet 500.

Ndemanga za Langerin

Anton, wazaka 48, Oryol: “Kwa zaka zitatu ndakhala ndikudwala matenda a shuga. Dokotala adamuuza mankhwalawo. Ndili wokondwa kuti palibe mavuto ena alionse, ndipo shuga sakukwera. ”

Anna, wazaka 31, ku Moscow: “Ndimadwala matenda a shuga a 2, ndakhala ndikudwala pafupifupi zaka zisanu. Chaka choyamba adakwanitsa kuchuluka kwa glucose kudzera mukuchita masewera olimbitsa thupi komanso kudya. Komabe, sizinachite bwino. Dotolo adapereka mankhwalawa pa mlingo wa 850 mg kawiri pa tsiku. Palibe mavuto. ”

Vasily, wazaka 28, Krasnodar: “Matenda a shuga a 2 adapezeka zaka zoposa zapitazo. Ndikumwa mankhwalawa. Dokotalayo akuti amagwira ntchito bwino komanso amasunga glucose yachilendo. Anatenga osachepera 500 mg. Kugwiritsa ntchito mankhwalawa kuyenera kukhala kosadukiza, palibe zotsatira zoyipa, ndikuganiza kuti mankhwalawa ndiabwino. ”