Mapiritsi ochepetsa magazi m'thupi: mndandanda wa mankhwala othandiza kwambiri

Akatswiri amati cholesterol ndi "yabwino" komanso "yoyipa." Yoyamba imakhala ndi lipoproteins yapamwamba kwambiri (HDL) ndipo imayang'anira kapangidwe ka vitamini D ndi mahomoni angapo, komanso kusungabe chitetezo chathupi mthupi la munthu. Cholesterol yoyipa imaphatikizapo ma lipids otsika kwambiri, omwe amadziwika chifukwa cha zovuta zawo pamitsempha yamagazi, mulingo wawo uyenera kutsitsidwa.

Magulu ndi magulu a mankhwala omwe amathandiza kuchepetsa cholesterol

Cholesterol ndi chinthu chama protein omwe amapangidwa ndi chiwindi kapena kulowa nacho ndi chakudya. Kuchokera pamenepo, amasuntha kudzera mu chikhodzodzo cha ndulu ndi duodenum, akuchita nawo chimbudzi. Akamaliza ntchito yawo, lipoproteins imasiya thupi ndi zinthu zopukutidwa.

Mafuta m'thupi

Pogwiritsa ntchito chiwindi chodontha kapena kufinya kwa ma ducts a bile, cholesterol imasungidwa m'thupi ndikukhazikika pazitseko zamitsempha yamagazi, potero zimayambitsa kutsekeka kwawo komanso matenda monga ischemia, kugunda kwamtima ndi stroko. Zofanana ndi zomwe zimapezeka mu cholesterol m'magazi a munthu wamkulu ndi izi:

  • Kwa cholesterol yonse: pansipa 5.2 Mmol / L
  • Lipoproteins wapamwamba kwambiri - oposa 1 mmol / l
  • Ndi kachulukidwe kochepa - zosakwana 3.5 mmol / l
  • Triglycerides - ochepera 2 Mmol / L

Kusunga izi ndizofunikira kwambiri, ndipo ngati zakuphwanya ziyenera kubwezeretsedwanso. Pachifukwa ichi, magulu azamankhwala ndi othandizira amapangidwa:

  1. Statins ndi gulu lothandiza lomwe limalepheretsa kugwira ntchito kwa ma enzymes opanga cholesterol.
  2. Probucol - njira yochepetsera mulingo wa mafuta onse oyipa ndi abwino, omwe samakhudza boma la triglycerides.
  3. Ziphuphu - gulu la mankhwala omwe amachepetsa kuchuluka kwa triglycerides m'magazi.
  4. Nicotinic acid ndi Benzaflavin ali m'gulu la mavitamini B, kugwiritsa ntchito kwawo kwakanthawi kumathandizira kuchepetsa cholesterol yoyipa, ndikuchepetsa kwambiri ngozi yamagazi.
  5. Mankhwala omwe amachepetsa matumbo a cholesterol mayamwidwe. Amathandizira kuchepa kwa mafuta m'thupi, motero amachepetsa kuchuluka kwake m'magazi.
  6. Otsatira a bile acids amachichotsa mthupi. Ndikusowa ma acid awa, chiwindi chimayambitsa kaphatikizidwe wa cholesterol wathanzi yambiri.

Chifukwa chake, mndandanda wa mankhwala kuthana ndi cholesterol yayikulu ndi wamkulu kwambiri. Kusankhidwa kwa mankhwala oyenera kwambiri kumachitika bwino molumikizana ndi dokotala, potengera kuchuluka kwa magazi ndi zosowa zamagulu ena ake.

Ma Statin, malo awo ndi mawonekedwe a pulogalamuyi

Ma Statin amatengedwa kuti ndi gulu labwino kwambiri komanso lotchuka la mankhwala omwe amagwiritsidwa ntchito pochiza ma pathologies omwe amagwirizana ndi cholesterol yayikulu yamagazi. Kutha kwa kaphatikizidwe ka LDL (otsika kachulukidwe lipids) m'thupi kumabweretsa kutsekeka kwawo kogwira ntchito ndikumasulidwa ku magazi. Molingana ndi tsiku lakukonzekera kwawo ndikuyamba kugwiritsa ntchito mankhwala, ndalamazo zimagawika m'mibadwo inayi:

  1. Ma statins a m'badwo woyamba akuphatikizapo Pravastatin, Simvastatin ndi Lovastatin. Mphamvu zawo pa cholesterol ndizocheperako poyerekeza ndi zamankhwala atsopano, ndipo zotsatira zoyipa zimawonedwa pafupipafupi ndipo zimatchulidwa kwambiri.
  2. M'badwo wachiwiri umaphatikizapo zinthu zopangidwa ndi fluvastatin (mwachitsanzo, Leskol Forte). Ndalamazi zimapatsidwa mphamvu yotalikirapo, chifukwa cha kuchuluka kwa zinthu zomwe zimachitika. Amatsutsidwanso nthawi zambiri chifukwa cha kupezeka kwa mavuto.
  3. Ma statin a m'badwo wachitatu akuphatikizapo Atorvastatin (Atoris, Atomax, Tulip, Liptonorm, ndi zina). Mankhwalawa sangangotsitsa kuchuluka kwa triglycerides ndi LDL, komanso kuwonjezera mwandalama mafuta m'thupi.
  4. Mwa mankhwala a m'badwo wachinayi (watsopano) wa Roxer, Akort, Rosulip, Tevastor, etc. Chofunikira chawo chachikulu ndi rosuvastatin. Sayansi siyimayima ndipo zomwe zachitika posachedwa zimaphatikiza chitetezo chokwanira komanso ntchito yabwino.

Kutenga ma statins ndikulimbikitsidwa masana, monga cholesterol yambiri imapangidwa usiku. Kuchepetsa kapena kuthetsa mavuto, munthawi yamankhwala, madokotala amakulangizani kuti mutenge Coenzyme Q10, muyezo wa 200 mg wa tsiku lililonse.

Mankhwala a m'badwo woyamba amapangidwa pamaziko a zinthu zachilengedwe, zonse zotsatirazi zimapangidwa pazinthu zopangidwa. Komabe, izi sizitanthauza kuti ali otetezeka. Mapiritsi a chilengedwe enieni kulibe, onse omwe adatchulidwa ali ndi zovuta zina komanso contraindication, chifukwa chake amayenera kumwedwa pokhapokha ngati akuwuzidwa ndi dokotala.

Kugwiritsa ntchito michere ya fibroic

Pamodzi ndi ma statins, kuti muchepetse cholesterol pazomwe zimapangidwa ndimagazi, ma fibrate amagwiritsidwa ntchito kwambiri (mankhwala omwe amapangidwa pamaziko a fibroic acid). Kuchita kwa mankhwalawa ndikulimbikitsa kupondereza kupanga LDL ndi triglycerides ndi kuwonjezeka panthawi yomweyo pamlingo wa HDL (cholesterol yopindulitsa).

Clofibrate anali woyimirira woyamba wa gululi, lomwe limagwiritsidwa ntchito ponseponse kuchiza mtima wamatenda, koma anali ndi zovuta zoyipa. Popita nthawi, chidachi chinapangidwanso, zomwe zidapangitsa kuti pakhale mtundu watsopano wa mafupa: Bezafibrat, Fenofibrat, Tsiprofibrat ndi Gemfobrozil. Mankhwalawa ndi oopsa kwambiri komanso otetezeka m'thupi la munthu, ndipo amatha kuchepetsa kuchuluka kwa mafuta achilengedwe m'magazi komanso kuwonjezera mphamvu ya mankhwala operekedwa chifukwa cha matenda ashuga.

Zotsatira zoyipa zochizira zotupa za fibroic acid zimaphatikizapo:

  • kupweteka: mutu, minofu ndi m'mimba
  • maluwa, kukondwerera
  • kusowa kwa chakudya ndi kumva pakamwa pouma
  • nseru ndi chizungulire
  • thupi lawo siligwirizana

Mankhwala opangidwa ndi Fibroic acid sakhazikitsidwa kwa amayi apakati komanso oyembekezera, achinyamata nthawi yakutha msanga, odwala omwe ali ndi vuto lalikulu la hepatic komanso aimpso. Mankhwalawa amagwiritsidwa ntchito mosamala komanso muyezo waukulu kuti muchepetse cholesterol mwa anthu omwe ali ndi matenda am'mimba komanso thirakiti la m'mimba.

Ndalama zomwe zimatulutsidwa pamaziko a fibroic acid siziphatikizidwa ndi mankhwala onse. Chifukwa chake, ndikosayenera kwambiri komanso koopsa kugwiritsa ntchito mankhwala osagwiritsa ntchito.

Otsatira a bile acid

Kwambiri pamankhwala amakono, ma bile acid sequestrants (FFAs) amagwiritsidwa ntchito kutsitsa cholesterol. Zitha kugwiritsidwa ntchito palokha komanso panthawi yovuta mankhwala, monga othandizira. Gululi limaphatikizapo mankhwala monga Kolesevelam, Cholestyramine ndi Colestipol.

Liwuli limaphatikizidwa, limatha kutanthauziridwa kuti "kudzipatula", kutanthauza kuti, FFA imalepheretsa kuyamwa kwa ma asidi a bile ndi cholesterol m'matumbo ndi chiwindi, motero, kwakukulu kumachotsedwa m'thupi popanda kulowa m'magazi. Chifukwa chake, LDL ikusiya mwachangu thupi la munthu, motere, kuchuluka kwa cholesterol yoyipa m'magazi kumachepa.

Chofunikira kwambiri pa FFAs ndikuti samayikidwa m'magazi ndipo ndiye otetezeka kwathunthu. Mankhwalawa amaperekedwa ngakhale kwa ana ndi amayi apakati. Komabe, magulu awa amalimbikitsidwa kuphatikiza kudya kwa FFA ndi folic acid ndi kukonzekera komwe kumakhala ndi chitsulo.

Mndandanda wochepa wazotsatira zoyambitsidwa ndi FFA:

  • kudzimbidwa ndi dyspepsia (kugaya chakudya kwakanthawi)
  • kutentha kwa mtima kapena nseru
  • chisangalalo ndi kuphuka

Zizindikiro zonsezi ndizofatsa komanso zimadutsa mwachangu zachilengedwe, zovuta zoyipa zomwe zidamwa mankhwalawa sizinawonedwe. Mwa zina zoyipa, kusokonezeka ndi kutsekeka kwa biliary thirakiti, impso ndi chiwindi, komanso chizolowezi chodzimbidwa.

Zimatanthawuza zomwe zimaletsa mayamwidwe a cholesterol m'matumbo

Ndalamazi zimalepheretsa kuyamwa kwa cholesterol khoma la matumbo chakudya, motere, kubwerera kwake ku chiwindi ndikutulutsidwa m'mwazi kumachepetsedwa kwambiri. Monga zoletsa zomwe zimachepetsa mayamwidwe a cholesterol (ISAH) m'matumbo, Lipobon ndi Ezetrol amagwiritsidwa ntchito, komanso zakudya zowonjezera za Guarem.

Ubwino wa ndalamazi ndi monga:

  • Kutetezedwa kwakukulu, popeza kuti sikololedwa kulowa m'magazi.
  • Kuthekera kwa kugwiritsa ntchito kwawo mankhwala ovuta, kuphatikiza ndi ma statins ndi mankhwala ena.
  • Kusowa kwa contraindication kuti mugwiritse ntchito pakati pa anthu omwe ali ndi vuto la chiwindi ndi matenda.

Chida choyenera chomwe chimatenga cholesterol m'matumbo ndikuchichotsa m'thupi ndi gawo la Guarem. Ubwino wake wosasinthika:

  • mathamangitsidwe a excretion wa bile acid
  • Kulala kudya (anthu onenepa kwambiri nthawi zambiri amadwala mafuta ambiri)
  • kuyanjana bwino ndi mankhwala ena
  • kugwiritsa ntchito mosavuta (ma granules amangofunika kuwonjezera pa zakumwa zilizonse)

Nthawi zina, mavuto amabwera mu mawonekedwe a zakumwa zoziziritsa kukhosi, nseru, kupweteka m'matumbo ndi bata. Zizindikirozi zimatha msanga, nthawi zambiri pazokha, pomwe cholesterol imakhala mwadongosolo komanso yochepetsedwa kwambiri.

Mankhwala a ISAH amalimbikitsa ndikuwonjezera kugwira ntchito kwa ma statins, koma nthawi yomweyo, amatha kuputa ndikukulitsa zotsatira zake zoyipa zikagwiritsidwa ntchito limodzi. Amayesedwa mu akazi panthawi yoyembekezera komanso mkaka wa m'mawere.

Nicotinic acid

Chithandizo china chomwe chimatsitsa cholesterol m'mwazi ndi Nicotinic acid kapena Niacin. Mankhwala opangidwa pamaziko a nicotinic acid: Niceritrol, Acipimox, Enduracin amachepetsa kuchuluka kwa cholesterol yoyipa m'magazi ndikuchepetsa chiopsezo cha kuundana kwa magazi.

Zotsatira zoyipa zomwe zimachitika mthupi la nicotinic acid ndi:

  1. Kutentha kwa thupi kumtunda ndi nkhope.
  2. Thupi lawo siligwirizana.
  3. Matenda am'mimba (osavomerezeka kwa anthu omwe ali ndi vuto la gastritis ndi matenda am'mimba am'mimba).
  4. Kuchuluka kwa shuga mu shuga.

Popeza kuti pali zovuta zomwe zingachitike, chithandizo cha nicotinic acid chimayamba ndi milingo yochepa, pang'onopang'ono amawonjezera. Mankhwalawa amachitika moyang'aniridwa ndi kuyang'aniridwa ndi dokotala. Kuti mukwaniritse zotsatira zabwino, njira yayitali yothandizira imafunikira.

Enduracin - mankhwala a mbadwo watsopano wobwera chifukwa cha nicotinic acid ndiwosavuta kunyamula ndipo ali ndi zovuta zosavomerezeka. Komabe, kupatula pamenepo, kukonzekera konse komwe kumakhazikitsidwa kumapangidwira matenda amtundu wa chiwindi, kusokonezeka kwakukulu kwa mtima, kugunda komanso zotupa zam'mimba za duodenum ndi m'mimba.

Njira zina zochepetsera cholesterol

Kuchepetsa cholesterol, zofunikira ndizakudya, moyo wokangalika wolimbitsa thupi, kusiya kulemera mopambanitsa ndi kusiya zizolowezi zoipa (mowa ndi kusuta). Zakudya zazikulu za tsiku ndi tsiku za munthu wokhala ndi cholesterol yayikulu ziyenera kukhala ndi nsomba zam'nyanja ndi mitsinje, nyama yamafuta ochepa, zakudya zamasamba ndi zipatso, chimanga, tiyi wobiriwira, mitundu yosiyanasiyana ya chimanga ndi mkaka wokhala ndi mafuta ochepa.

Makangaza amatsitsa cholesterol

Zakudya zomwe zimathandiza cholesterol yotsika zimaphatikizapo avocados ndi zipatso zakutchire, pistachios, amondi ndi sesame, oatmeal ndi ma legamu, amadyera ndi kabichi, mafuta a azitona ndi nsomba zam'nyanja. Zakudya zoyenera pafupipafupi zimathandizira kuchotsa zolembera zamtunduwu m'thupi ndikukulitsa kupanga lipids zabwino. Nthawi zambiri mutha kuthana ndi cholesterol yowonjezereka ndi zakudya komanso kukonza njira, popanda kugwiritsa ntchito mankhwala.

Zowonjezera zimagwiritsidwa ntchito kwambiri kuti pakhale matenda a cholesterol komanso kupewa atherosulinosis. Poyerekeza ndi malingaliro abwino, otchuka kwambiri a iwo ndi awa: Fibropeket, Ateroklefit, Verbena - zombo zoyera ndi Vita Taurin. Izi zowonjezera, zosokoneza mayamwidwe a LDL ndikuzisilira, zimakhala ndi phindu pamitsempha yamagazi ndi mtima, zimakhazikitsa chiwindi ndi dongosolo lonse logaya chakudya.

Musaiwale zamankhwala azikhalidwe, pamenepa sizothandiza, koma ndizotetezeka. Nayi maphikidwe otsimikiziridwa ndi zokumana nazo ndi nthawi:

  1. Kulowetsedwa kwa Propolis kuyeretsa ziwiya, ndikukonzekera kunyumba sikungakhale kovuta. Propolis ikhoza kugulidwa pamsika kuchokera kwa othandizira njuchi komanso ogulitsa uchi. Chochita chimathiridwa ndimowa (makamaka makumi asanu ndi awiri peresenti, komanso vodka) mu gawo la 10 g ya phula pa 90 g yamadzi. Muyenera kumanenanso mankhwalawa kwa milungu iwiri, mumdima wofunda. Tsiku lililonse kangapo ndikofunikira kugwedeza mwamphamvu botolo ndi zomwe zilimo.
    Tengani katatu patsiku, musanadye, madontho asanu ndi awiri osungunuka mu kapu yamadzi. Njira ya chithandizo ndi miyezi inayi.
  2. Dryion muzu wouma ndi njira yabwino yochepetsera cholesterol komanso kupewa atherosulinosis. Muzu wa chomeracho uyenera kukumbidwa, kutsukidwa bwino ndikuwuma, kenako ndikuphwanyidwa pogwiritsa ntchito matope kapena khofi kupukuta. Supuni ya tiyi waumaliza uyenera kudyedwa musanadye chakudya chilichonse kwa miyezi isanu ndi umodzi.
  3. Zipatso za Rowan ndizothandiza kwambiri kuthetsa vuto la cholesterol. Zitha kudyedwa mwatsopano mzanu musanadye, kapena mutha kukonza chokoma: kuwaza zipatsozo ndi chopukusira cha nyama ndikusakaniza ndi uchi molingana ndi 2/1. Sungani zosakaniza zomwe zili mufiriji ndikutenga 1 tsp. musanadye. Chida ichi chimapatsidwa mankhwala ambiri komanso kukoma kosangalatsa, koma m'magulu sichimagwirizana ndi omwe ali ndi vuto laling'ono.

Mwambiri, pali njira zambiri zochepetsera cholesterol, ndikofunikira kuti mutha kusankha njira yothandiza komanso yotetezeka makamaka yokhudza thupi lanu. Pakulimbana kwa thanzi la munthu ndi moyo wautali, monga kunkhondo, njira zonse zomwe zilipo ndi zabwino, ndipo pankhaniyi, thandizo la dokotala wodziwa bwino ndiye njira yabwino kwambiri.

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