Viktoza - jakisoni wa matenda ashuga

Bayeta (yankho la sc makonzedwe) → Zolemba mmalo: 13 Pamwamba

Analogue ndiyotsika mtengo kuchokera ku ma ruble 4335.

Wopanga: ASTRAZENECA UK Limited (Great Britain)
Kutulutsa Mafomu:

• Yankho la subcutaneous makonzedwe, 250 mcg / ml 1.2 ml, No. 1

Mtengo wa Baeta m'masitolo ogulitsa: kuchokera ku ruble 1093. mpaka 9431 rub. (Zopereka 160)
Malangizo ogwiritsira ntchito

Baeta - analogue ya Victoza, imapangidwa ku UK, USA ndi Russia mu zolembera za syringe ya 1.2 kapena 2.4 ml. Zomwe zimagwidwa ndi exenatide. Mankhwalawa amagwira pama receptor a glucagon-like peptide-1, amachititsa kuchuluka kwa insulini komanso kulepheretsa katulutsidwe wa glucagon, kuchepa kwa shuga m'magazi, kumachepetsa chilimbikitso, kupondereza kutuluka kwa m'mimba ndi matumbo, ndikuchepetsa mphamvu ya m'mimba ndi matumbo, ndikuchepetsa thupi. Monga monotherapy yophatikiza ndi zakudya komanso zolimbitsa thupi zolimbitsa thupi zimagwiritsidwa ntchito mwa odwala omwe ali ndi mtundu wa 2 shuga mellitus kuti azitha kuchepetsa kuchuluka kwa glucose komanso kuchepetsa thupi. Mankhwala ophatikizidwa amagwiritsidwa ntchito ngati mtundu wachiwiri wa matenda ashuga osakwanira metformin ndi mankhwala omwe amapezeka ndi sulfanylureas kuwonjezera pa iwo. Mankhwala kutumikiridwa subcutaneous kawiri pa tsiku, kuyambira limodzi mlingo 5 mg. Zitha kupangitsa kuti magazi achepetse, kusokonezeka kwakanthawi, matenda oopsa, kupweteka mutu, chizungulire, hypoglycemia, kuchepa thupi, kuchepa kwa chakudya, kugona, komanso kusowa kwa kapamba. Contraindicated vuto la tsankho, mtundu 1 shuga, matenda a impso, m'mimba thirakiti, pancreatitis pachimake, azimayi pa bere ndi kuyamwitsa, ubwana ndi unyamata.

Mlingo wa mawonekedwe ndi kapangidwe kake

Mankhwala Victoza akuimiridwa ndi yankho la subcutaneous makonzedwe. The yogwira ndi liraglutide. Madzi amadzimadzi amayikidwa mu cholembera chapadera ndi voliyumu ya 3 ml.

Yankho labwino silopanda utoto, sayenera kukhala ndi zosayera zilizonse. Matenda amtundu kapena matenthedwe amayenera kuchenjeza - mwina mankhwalawo afooka. Zithunzi zambiri za cholembera cha Victoza syringe zimatha kupezeka pazinthu zingapo za intaneti kuti mudziwe momwe mankhwalawa amayenera kuwonekera pasadakhale.

Mankhwala

Ma jakisoni a Victoza ndi othandizira amphamvu a hypoglycemic. Zotsatira zazikulu za mankhwala omwe amachititsa chidwi chenicheni kuchokera kwa akatswiri othandizira ndi ma endocrinologists:

1. Kukondoweza kwa mtundu wodalira shuga ndikupanga insulini,
2. Kuponderezedwa kwa glucagon wopangidwa ndi mtundu wodalira shuga,
3. Chitetezo ku zochitika zotsutsa za hypoglycemic,
4. Kuwongolera m'mimba chifukwa kuchepa pang'ono kwa mphamvu ya m'magazi (kuyamwa kwa glucose mukatha kudya kumachepetsedwa pang'ono),
5. Kutsika kwakukulu kwa kukokana kwa insulin pazomwe zili,
6. Kuchepetsa kwa shuga kwa magulu a chiwindi.
7. Kulumikizana ndi ma nuclei a hypothalamus kuti apange kumverera kogwira mtima komanso kuchepetsa nkhawa,
8. Kuwongolera kusintha kwa minofu ndi ziwalo za mtima dongosolo,
9. Kuthamanga kwa magazi,
10. Kupititsa patsogolo magazi.

Zambiri

Mankhwala Victoza, mogwirizana ndi malangizo ogwiritsira ntchito, amaperekedwa kamodzi patsiku. Mphamvu yayitali yogwira liraglutide imaperekedwa ndi njira zitatu:

1. Njira yochepetsera kuyamwa kwa mankhwala osokoneza bongo chifukwa chazoyenderana nawo,
2. Albumin Bundle
3. Mulingo wambiri wosasunthika wa ma enzyme angapo, kuloleza kuchotsa zotsalira zamankhwala, bola ngati zingatheke.

Victoza yankho limakhudza pancreatic kapangidwe kake, kukonza magwiridwe antchito a maselo a beta. Komanso pali kutsika kwapang'onopang'ono pakubisika kwa glucagon. Njira yogwirizanitsira ntchito za ma enzymes ndikugwira ntchito kwa kapamba palokha ndi yangwiro.

Kodi chithandizo chovuta kwambiri cha matenda am'thupi ndi chiti?

Mellitus wosadalira insulin ndi matenda amtundu wa endocrine pomwe ma cell amthupi amakana insulini yopangidwa ndi kapamba.

Zotsatira zake, maselo amalephera kumva kukoma kwa timadzi tam'magazi, glucose sangathe kulowa mu minofu, kudzikundikira m'thupi. Nawonso, kuwonjezeka kwamankhwala a insulin kumawonekeranso, chifukwa kapamba amayamba kupanga kuchuluka kwa timadzi timeneti.

Pakukonzekera kwa pathological process, pali kuphwanya njira zonse za metabolic mthupi, ziwalo zambiri zamkati ndi kachitidwe zimavutika.

Njira zamakono zochizira matenda zimatengera mfundo izi:

1. Kutsatira zakudya. Kusankhidwa kwamankhwala ndi zakudya zomwe sizingagwiritsidwe ntchito sizingothandiza kuchepetsa kuchuluka kwa shuga, komanso zimathandizira kuchepetsa kunenepa. Monga mukudziwira, chimodzi mwazinthu zomwe zimapangitsa kuti odwala asakhale ndi insulin-omwe amadalira shuga ndi kunenepa kwambiri.
2. Thupi lathupi limathandizanso kuchepetsa shuga la magazi. Nthawi zina zimakhala zokwanira kukhazikitsa moyo wokangalika, kuyenda tsiku ndi tsiku ndi mpweya wabwino komanso thanzi labwino, kotero kuti wodwalayo akumva bwino.
3. Mankhwala. Kubwezeretsanso shuga kunthawi zonse kumathandizanso mankhwala oyenera adokotala.

Mpaka pano, chithandizo cha matenda osokoneza bongo omwe amadalira shuga

• mankhwala omwe amachokera ku sulfonylurea. Machitidwe a pharmacological ndi othandizira kubisalira kwa insulin,
• mankhwala omwe akuphatikizidwa ndi gulu la Biguanide. Zotsatira zawo cholinga chake ndikuchepetsa kufunika kwa katemera wa insulin,
• Mankhwala omwe amachokera ku thiazolidinol amathandizira kuchepetsa shuga m'magazi ndipo amakhudza bwino mawonekedwe a lipid,
• ma insretins.

Ngati mankhwala omwe ali pamwambapa omwe amachepetsa shuga ya magazi samabweretsa zabwino, mankhwala a insulin angagwiritsidwe ntchito.

Chachikulu pharmacological zotsatira za mankhwala

Mankhwala Victoza, monga lamulo, amawerengedwa kwa odwala omwe ali ndi vuto losagwirizana ndi insulin, monga mankhwala othandizira. Njira yochiritsira yogwiritsa ntchito mankhwalawa imayenera kutsatiridwa ndi zakudya zapadera komanso kuchita masewera olimbitsa thupi. Pokhapokha ngati mutachita izi, mutha kukwaniritsa zotsatira zabwino za mankhwalawa.

Mankhwala a Victoza amapangidwa ndi omwe amapanga mwa njira yothetsera jakisoni wa subcutaneous. M'mapiritsi ndi mitundu ina ya mankhwala, mankhwalawa saperekedwa mpaka pano.

Mankhwala Victoza ndi analogue wa glucagon-ngati peptide-imodzi ya munthu, yopangidwa ndi njira yachilengedwe, ndipo 90% ikugwirizana nayo. Thupi limangirira ku ma receptor ena omwe amayang'aniridwa ndi ma insretin opangidwa ndi thupi. Nawonso, incretin ya mahomoni imapangitsa kuti inshuwaransi ipangidwe.

Zotsatira za mankhwalawa zimathandizanso kuchepetsa kupanga kwa insulin ngati mkhalidwe wa hypoglycemia umawonedwa. Chifukwa chake, kuchepa kwa thupi ndi kusintha kwa matendawa kumachitika, kuchuluka kwa mafuta kumatsika, ndikukula kwambiri kumatha.

Mankhwalawa amapezeka ngati syringe Viktoza cholembera chokhala ndi ma milliliters atatu. Chofunikira chachikulu pa mankhwalawa ndi liraglutide. Mankhwalawa amalowetsedwa mkati mwa maola asanu ndi atatu mpaka khumi ndi awiri, ndipo pokhapokha ngati nthawi imeneyi amatha kukhala m'magazi ambiri.

Chingoni cha Victoza cha syringe chimagulitsidwa makatoni apadera amtundu umodzi, jakisoni awiri kapena atatu. Kuphatikiza apo, ilinso ndi malangizo a boma ogwiritsira ntchito mankhwala omwe ali ndi zotsatirazi:

1. Upangiri wotsatira wa momwe mungakhazikitsire Victoza.
2. Mlingo woyenera.
3. Kugwiritsa ntchito singano moyenera.
4. Zotsatira zoyipa ndi contraindication.

Ma CD ndi ma singano amaikidwa mu katoni kapadera kagalasi, kameneka ndi cholembera chosokonekera. Syringe iliyonse ndi yokwanira milingo makumi atatu ya 0,6 mg. Ngati dokotala amupatsa wodwala waukulu, kuchuluka kwa jakisoni kumachepetsedwa. Jakisoni amachitidwa mosavuta, chinthu chachikulu ndikupeza maluso ena okuyika singano pansi pa khungu.

Zizindikiro zazikulu pakugwiritsa ntchito jakisoni wa mtundu 2 wa matenda a shuga malinga ndi mankhwalawa ndi motere:

• ngati mankhwala main
• pamodzi ndi mankhwala ena - Metformin, Glibenclamide, Dibetolongол
• ntchito ndi insulin mankhwala.

Kuphatikiza apo, mankhwalawa amatha kuperekedwa kwa odwala matenda a shuga ngati mankhwala ochepetsa thupi. Maganizo a odwala a Victoza akuwonetsa kuti mukamamwa mankhwalawa amachepetsa chilakolako cha kudya, matenda a shuga m'magazi amachitika.

Kuphatikiza apo, jekeseni wokhazikika kwa mwezi kumathandizira kuchepetsa kuchuluka kwa triglycerides.

Malangizo ogwiritsira ntchito mankhwalawa

Malangizo a Victoza ogwiritsira ntchito akuti kuyambika kwa mankhwalawa kuyenera kuchitika ndi milingo yotsika ya mankhwalawa. Chifukwa chake, kuyang'anira kwa metabolic kofunikira kumaperekedwa.

Mukamamwa mankhwalawa, wodwalayo ayenera kuyang'anira kuchuluka kwa shuga m'magazi. Mankhwala omwe amapezeka, komanso kuchuluka kwa jekeseni omwe amaphatikizidwa ndi jekeseni, amatsimikiziridwa ndi adokotala okha. Pankhaniyi, kudzipereka palokha ndi koletsedwa.

Mankhwala Viktoza amaperekedwa kamodzi patsiku, popeza zochita za liraglutide zimayamba kuchitika pakapita nthawi.

Jakisoni wa Victoza amayenera kuperekedwa pansi pa khungu pamalo amodzi osavuta:

Poterepa, jakisoni wa singano samatengera chakudya chachikulu. Monga lingaliro, zimawonedwa kuti ndizoyenera kusunga nthawi yomweyo pakati pa jakisoni. Tiyenera kudziwa kuti mankhwala a Viktoza saloledwa kulowa kudzera m'mitsempha kapena intramuscularly.

Kuchuluka kwa Mlingo woyenera kumadalira kukula kwa kuchuluka kwa matendawo ndi mikhalidwe ya wodwalayo. M'magawo oyamba a chithandizo chamankhwala, tikulimbikitsidwa kupaka jekeseni kamodzi patsiku, womwe udzakhale 0,6 mg wa liraglutide. Osati kale sabata limodzi chiyambireni kuyambika kwa mankhwalawa, kuwonjezeka kwa Mlingo mpaka 1,2 mg wa mankhwala patsiku amaloledwa. Kukula kulikonse kwa mankhwalawa kuyenera kuchitika ndi masiku osachepera asanu ndi awiri.

Mulingo wambiri wa liraglutide woperekedwa sayenera kupitirira 1.8 mg.

Nthawi zambiri pamankhwala ovuta, mankhwala amagwiritsidwa ntchito molumikizana ndi Metformin kapena mankhwala ena ochepetsa shuga. Pankhaniyi, Mlingo wa mankhwalawa amatsimikiziridwa ndi adokotala.

Monga momwe zamankhwala zimasonyezera, pakuthandizira kwa matenda okalamba mu okalamba, mulingo woperekedwa wa mankhwalawo sunasiyane ndi omwe alembedwa pamwambapa.

Ndemanga za Victoza za akatswiri azachipatala amawirikiza poti kugwiritsa ntchito mankhwalawa kuyenera kuchitika pokhapokha ngati akuwuzidwa ndi adokotala. Pankhaniyi, mutha kupewa kuwonetsa zotsatira zoyipa ndikusankha mlingo woyenera.

Ndikofunika kusunga mankhwalawo mufiriji pa kutentha kwa madigiri awiri mpaka asanu ndi atatu.

Amaloledwanso kusiya mankhwalawo m'malo omwe kuwala kwa dzuwa sikulowa, bola kutentha sikupitirira madigiri sate.

Ndi ziti zotsutsana zomwe zimagwiritsidwa ntchito?

Monga mankhwala ena aliwonse, Victoza ali ndi zotsutsana zingapo kuti agwiritse ntchito.

Ma contraindication onse omwe akupezeka amawonetsedwa mu malangizo ogwiritsira ntchito mankhwalawa.

Ndi achire njira yochizira ndi Viktoza, ndikofunikira kuganizira zonse zotheka zotsutsana ndi ntchito yake.

Liraglutide sayenera kugwiritsidwa ntchito pazotsatirazi:

• Hypersensitivity gawo limodzi kapena zingapo za mankhwalawa
• odwala omwe ali ndi matenda a shuga a shuga-
• ngati wodwala ali ndi matenda a shuga a ketoacidosisꓼ
• mavuto ndi yachibadwa ntchito impso
• vuto pamavuto a chiwindiꓼ
• ngati maluso a genitourinary systemꓼ
• ngati pali matenda amitsempha yama mtima, kukhumudwa mtima
• kukula kwa njira yotupa m'matumbo, komanso matenda ena a ziwalo zam'mimba thirakiti (kuphatikizapo paresis yam'mimba) ꓼ
• ana ochepera zaka khumi ndi zisanu ndi zitatu ndi odwala atatha zaka makumi asanu ndi awiri ndi zisanuꓼ
• atsikana pa nthawi yoyembekezera komanso mkaka wa m'mawere.

Kafukufuku wazachipatala awonetsa kuti ndizovomerezeka kuti azimayi amwe mankhwala pa nthawi yomwe ali ndi pakati. Pali chiopsezo chachikulu cha zotsatira zoyipa za chinthu chomwe chikukula pakubadwa kwa mwana ndi moyo wake. Muyenera kupewa kugwiritsa ntchito mankhwalawa ngakhale panthawi yakubadwa kwa mwana wosabadwa. Ponena za nthawi ya mkaka wa m'mawere, madokotala akuti Viktoza kwenikweni simalowa mkaka wa m'mawere. Pankhaniyi, ngakhale mkamayamwa, sikulimbikitsidwa kumwa mankhwala.

Popeza mankhwalawa amagwiritsidwa ntchito pochiza matenda ashuga komanso amathandizira pakukula kwa kulemera kwa odwala am'gulu lino, anthu ena athanzi amagwiritsa ntchito ngati njira yochepetsera thupi.

Madokotala amalimbikitsa kuti asamagwiritse ntchito zinthu ngati izi, chifukwa pamakhala chiopsezo chachikulu chotenga khansa ya chithokomiro mukamamwa mankhwalawa mwa anthu athanzi.

Zokhudza mankhwalawa

Matenda a shuga ndi mkhalidwe womwe ubale wa insulin (mahomoni a kapamba) ndi shuga (chakudya chomwenso chimabwera ndi chakudya m'thupi) zimasokonekera. Zotsatira za kulumikizidwa kwathyo ndi hyperglycemia. Wogwiriridwa ndi mankhwala omwe mankhwala ake amagwira ntchito amathandizira glucagon-ngati peptide-1 receptors ndikuwonjezera katemera wa insulin.

Mankhwala ndi a njira zaposachedwa kwambiri pochizira matenda a shuga a 2. Gawo logwira (liraglutide) lili pafupi kwambiri ndi insulin yachilengedwe, chifukwa chake limakhala ndi chithandizo chachikulu.

Wothandizira wa hypoglycemic adapangira makatani osokoneza. Nditalandira gawo logwira, zotsatirazi zimachitika:

• kapamba amayambitsa,
• kuchuluka kwa insulin,
• kuchuluka kwa maselo a beta kumachuluka
• kumverera kwanjala kumachepera.

Mu zovuta, zonsezi zimabweretsa kukula kwa shuga. Khalidwe lofunika kwambiri la Victoza ndikupewa kufa kwa ma cell omwe akufuna, omwe amatsogolera pakukula kwakanthawi kwa endocrine pathology.

Chifukwa cha kulumikizana ndi mapuloteni am'madzi am'magazi, mphamvu ya mankhwalawa imapitilira maola 24. Zinthu zomwe zimagwira sizisintha ndipo zimatha kudzikundikira, chifukwa zimachoka m'thupi pakatha masiku 8.

Kuyembekezera kugwiritsa ntchito Victoza

Wogulitsa mankhwala ali ndi zinthu zingapo zabwino (kuwonjezera pa zochita za hypoglycemic), kufunika komwe kumadza ndi vuto la endocrine.

• kusintha kwa magazi kumankhwala ndi ziwalo,
• malamulo am'mimba
• Kuchira kwa BP,
• kupangidwa kwa glucagon ndi minyewa ya chiwindi mumitengo yoyenera,
• zimagwira ntchito kwamikodzo.

Ngati yogwira ntchito ikakhudzana ndi hypothalamus, kufunafuna kosalekeza "kudya" kumachepetsedwa, monga wodwala amamva bwino panthawi ya mankhwala.

Zizindikiro zogwiritsidwa ntchito

Njira yokhayo yomwe ingagwiritsidwe ntchito ndi shuga mellitus wa mtundu wosadalira insulini (monga monotherapy). Kuphatikiza apo, mankhwalawa amaphatikizidwa ndi mankhwala a pakamwa, koma pokhapokha pochiza matenda a shuga a 2. Izi zimachitika makamaka chifukwa cha gawo lomwe limagwira, lomwe limathandizira kaphatikizidwe ka timadzi ta pancreatic, kukhudza maselo a beta.

Kutulutsa Fomu

Victoza ndi yankho la subcutaneous makonzedwe, matenda a shuga magazi ndi kufulumizitsa kagayidwe kachakudya njira mu odwala matenda ashuga. Njira yothirayo imathiridwa mu zolembera za 3 ml:

Kuzindikira kwa shuga - ingomwani tsiku lililonse.

• Mlingo 30 - 0,6 mg
• Mlingo 15 - 1,2 mg
• Mlingo 10 - 1,8 mg.

Mlingo wofunikira umayikidwa musanayambike makonzedwe ndikupukutira kapu yayikulu.

• 2 syringe ya pulasitiki yokhala ndi mulingo wofanana
• malangizo ogwiritsa ntchito.

Singano za insulin sizikuphatikizidwa mu kit, chifukwa chake zimagulidwa mosiyana.

Zofunikira pa singano zogulira:

1. Olimba "NovoFayn" kapena "NovoTvist."
2. Kutalika kosaposa 8 mm.
3. Kunenepa kwambiri 32.

Ma singano amapukusidwa mu dzenje pansi ndikugwiritsidwa ntchito kamodzi (kutaya jakisoni wani wa Viktoz).

Mankhwala ochizira matenda a shuga a II amawonjezera. Mtengo wamba wa 3 ml pakakhala 18 mg ndi ma ruble 9650. Wopanga ndi Novo Nordiks (Denmark).

Yogwira pophika mankhwala ndi liraglutide - chinthu chomwe chimapukusidwa ndi biotechnology, pafupi kwambiri ndi mahomoni aumunthu (pafupifupi wathunthu wa insulin). Mu 1 ml ya mankhwala - 6 mg a liraglutide. Gawoli lili ndi mphamvu ya hypoglycemic.

Zigawo zothandiza ndi:

• phenol
• propylene glycol
• sodium hydrogen phosphate,
• hydrogen chloride (asidi),
• madzi osungunuka.

Njira yokhazikika, yopanda utoto imathiridwa mu cartridge, yomwe imasindikizidwa mu chidebe cha pulasitiki (syringe cholembera). Kuyimitsidwa kapena kusinthasintha kwa madzi ndi kosavomerezeka.

Ndi zotulukapo zoipa ziti zomwe zingachitike?

Mukamagwiritsa ntchito mankhwalawa, zotsatira zoyipa zimatha kuchitika.

Kulephera kutsatira malingaliro a dokotala yemwe akupezekapo, kunyalanyaza zomwe zalembedwa mu malangizo ogwiritsira ntchito mankhwalawa, kungayambitse mavuto.

Makamaka, kuwonetsa koipa kotere kumapezeka pa magawo oyamba a njira yochizira.

Zotsatira zoyipa zomwe zimadza chifukwa ch kumwa mankhwalawa ndi kuwonekera kwa zotsatirazi:

1. Kuphwanya kagayidwe kachakudya njira. Zomwe zikuluzikulu ndizochita mseru, kusanza, kutsegula m'mimba kapena kudzimbidwa, kupweteka pamimba, kutaya kwathunthu chilakolako cha chakudya. Nthawi zina, madzi amawonongeka.
2. Mitsempha yapakati imatha kupereka zizindikiritso zam'mutu kwambiri.
3. Zotsatira zoyipa za ziwalo zam'mimba zambiri zimachitika, monga kukula kapena kufalikira kwa gastritis, gastroesophageal Reflux, belching, bloating ndi kuchuluka kwa mpweya. Osowa kwambiri, odwala amadandaula za chitukuko cha pancreatitis pachimake.
4. Kusokonezeka kwa dongosolo lamagetsi kumatha kuwonetsa monga anaphylactic reaction.
5. Mu mawonekedwe opatsirana njira ya chapamwamba kupuma thirakiti.
6. Zotsatira zoyipa kuchokera jakisoni.
7. Kutopa kwathupi komanso thanzi lathanziꓼ
8. Kuchokera ziwalo za genitourinary system, zotsatira zoyipa zimadziwonetsa ngati kulephera kwa impso, kusokonekera bwino kwa impso ntchitoꓼ
9. Mavuto ndi khungu. Nthawi zambiri, izi zimadzionetsa ngati zotupa pakhungu, urticaria, komanso kuyabwa.

Mu mawonekedwe a hypoglycemia, zovuta zomwe zimachitika mwa odwala ndizochepa kwambiri. Izi zimatha kuchitika ngati mankhwalawa sanawonedwe bwino, makamaka pophatikiza mankhwala ena okhala ndi shuga. Muzochita zamankhwala, hypoglycemia yoopsa idadziwika mu shuga ndikuphatikizira Viktoza ndi mankhwala ochokera ku gulu la zotumphukira za sulfonylurea.

Kuphatikiza apo, kumwa mankhwalawa nthawi zina kumatha kukhala limodzi ndi kusintha kwa thupi lawo siligwirizana, komwe kumawonekera mu mawonekedwe a urticaria, totupa, kupumira movutikira, komanso kuwonjezeka pafupipafupi kumenyedwa kwa mtima.

Ndi mankhwala osokoneza bongo ochulukirapo maulendo makumi anayi, adakanidwa m'njira ya mseru komanso kusanza kwambiri. Nthawi yomweyo, kuchuluka kwa shuga m'magazi sikunagwere kwambiri.

Ngati bongo, tikulimbikitsidwa kutsatira malangizo a dokotala ndikupita njira yodziwika bwino yochizira.

Kodi ndizotheka kusintha Viktoza ndikugulitsa ndi katundu wofanana?

Mpaka pano, pamsika wa pharmacological mulibe chithunzi chonse cha mankhwala a Viktoza.

Mtengo wa mankhwalawa, choyambirira, zimatengera kuchuluka kwa zolembera m'matumba.

Mutha kugula mankhwala mumasitolo amzinda kuchokera ku ruble 7 mpaka 11,2.

Mankhwala otsatirawa ndi ofanana mu zotsatira zawo zamankhwala, koma ndi mankhwala ena:

1. Novonorm ndi piritsi lomwe limakhala ndi kuchepetsa shuga m'thupi. Wopanga mankhwalawa ndi Germany. Chofunikira chachikulu pa chinthu ndi mankhwala. Nthawi zambiri amagwiritsidwa ntchito posagwiritsa ntchito mankhwala osokoneza bongo omwe amadalira shuga, monga chida chachikulu kapena kuphatikiza mankhwala ndi metformin kapena thiazolidinedione. Mtengo wa mankhwalawa, kutengera mlingo, umasiyana kuchokera ku ma 170 mpaka ma ruble 230.
2. Baeta ndi mankhwala osokoneza bongo omwe amadziwika kuti ndi othandizira polimbana ndi zovuta za matenda a shuga. Amapezeka mu mawonekedwe a yankho la subcutaneous jakisoni. Chofunikira chachikulu ndi exenatide. Mtengo wamba wa mankhwalawa m'masitolo ndi ma ruble 4,000.

Kuphatikiza apo, analogi ya mankhwala Viktoza ndi Luxumia

Dokotala wokhayo ndi amene angaganize zofunikira pakuthandizira mankhwalawa panthawi ya achire.

Kanemayo munkhaniyi amafotokoza za mankhwala omwe amachepetsa shuga ya magazi.

Sonyezani shuga lanu kapena sankhani jenda pamayendedwe Kusaka OsapezekaKusaka Kuyang'ana kosapezeka

Amaona kuti imathandiza kwambiri kuwonda mopitirira muyeso II shuga mellitus mankhwala a "Victoza", ndemanga.

Kuchepetsa thupi kumachitika chifukwa cha zomwe zimachitika m'thupi la liraglutide, zomwe zimachepetsa kugwira ntchito kwa kapamba, zimachepetsa shuga m'magazi, zimachepetsa kugaya chakudya, zomwe zimapatsa thupi lamunthu kumva kuti limatopa. Mankhwalawa ndi oopsa ndipo ayenera kugwiritsidwa ntchito pokhapokha ngati akuwuzidwa ndi dokotala.

Kupanga ndi mawonekedwe a kumasulidwa

Akuchenjeza kuti si aliyense amene angagwiritse ntchito mankhwalawa "Victoza", ndemanga. Kuchepetsa thupi kumawonetsedwa kokha kwa anthu omwe ali ndi matenda amtundu wa II, anthu ena onse azigwiritsa ntchito mosamala kwambiri, chifukwa kuchepa kwambiri kwa shuga m'magazi kungayambitse hypoglycemia.

Mankhwalawa amapangidwa ku Denmark ndi Novo Nordisk A / C mwa njira yankho. 1 ml ili ndi pafupifupi 6 ml ya liraglutide. Katunduyo ndi wopanda khungu komanso wopanda fungo. Zothandiza pazomwe zimapangidwira mankhwalawa ndi sodium hydroxide, propylene glycol, sodium hydrogen phosphate dihydrate, phenol, madzi osungunuka.

Njira yothetsera Victoza imayikidwa mu cartridge yamagalasi, yomwe, imasindikizidwa mu cholembera kuti ilowe m'malo ambiri. Idzaza pabokosi lamakatoni, kuphatikiza pa malangizo, pakhoza kukhala 1 pena 3 syringe pensulo. Syringe iliyonse imapangidwira milingo makumi atatu a 0,6 mg, jakisoni khumi ndi awiri a 1,2 mg ndi jakisoni khumi oopsa a 1.8 mg.

Tsiku lotha kukonzekera kwake kosindikizidwa ndi miyezi 30. Osagwiritsa ntchito mankhwalawa tsiku litasonyezedwa phukusi. Njira yothetsera vutoli iyenera kusungidwa mufiriji pa kutentha kwa 2-8 ° C. Sayenera kuzizira. Alumali moyo wa cholembera womwe umagwiritsidwa ntchito ndi mwezi umodzi.

Amati zimathandiza kutaya mapaundi owonjezera pogwiritsa ntchito mankhwalawa "Victoza", ndemanga. Kuchepetsa thupi kumachitika chifukwa cha kuchuluka kwa shuga m'magazi ndi kuchepa kwa chilimbikitso.

Mphamvu ya mankhwalawa idafufuzidwa ndi asayansi aku Europe pa anthu onenepa kwambiri. Anthu 564 adatenga nawo gawo pazoyeserazi. Maphunzirowa adagawika m'magulu atatu, ndipo onsewa anali m'manja mwa akatswiri.

Odwala amayenera kutsatira zakudya zoyenera, kuti achepetse zopatsa mphamvu zopatsa mphamvu ndikugwiritsa ntchito nthawi yolimbitsa thupi.

Nthawi yomweyo, gulu loyamba la otsutsa linatenga placebo, lachiwiri - "Xenical", ndi anthu ochokera pagawo lachitatu - "Victoza".

Zotsatira za kuyeseraku zikuwonetsa kuti mwa iwo omwe akutenga placebo, adatha kuchepetsa 30% yokha. Mu gulu la Xenical, pafupifupi 44% ya odwala omwe adachepetsa thupi adawonedwa. Kuchita bwino kwa gulu lachitatu kunali 75%.

Chizindikiro ichi chimadziwika ndi zotsatira zabwino za kuchepa thupi mwa anthu omwe amagwiritsa ntchito mankhwalawa "Victoza."

Malangizo ogwiritsira ntchito (ndemanga za odwala ena amazindikira kupweteka pamutu ndi mseru nthawi yanthawi yamankhwala othandizira ndi chida ichi) amalimbikitsa odwala omwe ali ndi matenda a shuga a mellitus II.

Mankhwalawa amachepetsa kudya, amakula bwino ndi odwala oterewa, amalimbitsa shuga. Odwala adakwanitsa kusunga kulemera komwe kwatayika chifukwa chogwiritsa ntchito mankhwalawa kwanthawi yayitali ngakhale atachotsedwa kwa Victoza.

Anthu omwe adagwiritsa ntchito mankhwalawa adazindikira kuchepa kwamphamvu kwa makilogalamu 7 mpaka 10 mwezi umodzi. Koma ngakhale izi zili choncho, Victoza ndi mankhwala oopsa kwambiri omwe amatha kuyambitsa zotsatira zosayembekezereka, choncho musanagwiritse ntchito muyenera kufunsa katswiri ndikuyezetsa thupi lonse.

Ngati lingaliro lokonda kuchepa thupi ndi Victoza ndikusautsa, ndiye kuphatikiza pa yankho, njira zowonjezerazo ziyenera kugwiritsidwa ntchito kuti muchepetse kunenepa kwambiri.

Njira zowonjezerapo zokuthandizani kuti muchepetse thupi ndi Victoza

Tiyenera kukumbukira kuti mukamagwiritsa ntchito mankhwala a Victoza (kuwunika kwa azimayi ena amawona kuchepa kwakuthupi mpaka 5 kg pamwezi, koma sanali kumva bwino nthawi zonse), njira zowonjezerazi zidzakhala zofunikira kuti muchepetse kunenepa.

Choyamba, muyenera kuwona zakumwa zakumwa ndi kumwa malita osachepera 1.5 a madzi oyera tsiku lililonse. Tiyi yobiriwira yopanda mafuta, icicory, madzi amchere ndi tiyi wamatenda amaloledwa monga zakumwa.

Pogwiritsa ntchito mankhwalawa, munthu sayenera kuyiwala za zolimbitsa thupi, zomwe zimayenera kuperekedwa tsiku lililonse kuyambira mphindi 30 mpaka ola limodzi. Izi zitha kukhala masewera olimbitsa thupi, masewera olimbitsa thupi opanga simulators, kuweramira, chingwe kulumpha, kuyenda njinga ndi kusambira, kusambira, kulimbitsa thupi. Ngakhale kuyenda wamba kumathandizira njira yochepetsera kunenepa.

Mukamachepetsa thupi ndi "Viktoza" muyenera kutsatira zakudya zoyenera. Zosankha ziyenera kukhala zopatsa mphamvu komanso zochepa. Zakudya zamafuta kwambiri, komanso mchere, zosuta, ndi zakudya zina, siziyenera kuyikidwa kunja. Ndikofunika kusiyira lokoma, okhuthala ndi zonunkhira. Zakudya zoterezi zimakuthandizani kuti muchepetse thupi pang'onopang'ono komanso kuti muwoneke mapaundi owonjezera mtsogolo.

Zochita zonsezi pamwambapa m'njira zopindulitsa kwambiri zimakhudza thanzi, kulimbitsa thanzi ndikuthamanga njira yochepetsera thupi.

Zotsatira za pharmacological

Mankhwala "Victoza" ali ndi katundu wa hypoglycemic. Ndemanga (kuchepa thupi kwa anthu odwala matenda ashuga pogwiritsa ntchito mankhwalawa kumachitika pang'onopang'ono, popanda kudumpha) zindikirani zotsatira zowoneka bwino ndi kuchepa thupi (mpaka 15 makilogalamu pamwezi) ndikusintha kwathanzi lanu.

Zomwe zimagwiritsa ntchito mankhwalawa ndi 97% yofanana ndi glucagon-peptide - GLP-1. Zimapezeka mwanjira yachilengedwe. Izi zimamangilira ku GLP-1 receptors, zomwe ndizomwe umalimbana ndi ma incretin opangidwa m'thupi la munthu.

Ndi insretin yomwe imakulitsa kupanga insulini poyankha kuchuluka kwa shuga m'magazi. Komanso mphamvu ya liraglutide mu kapangidwe kake ka mankhwala amalepheretsa kupanga shuga. Ngakhale izi, pamaso pa hypoglycemia, chinthu chogwira ntchito chimachepetsa kupanga insulin ndipo sichikhudza kupangika kwa glucagon mwanjira iliyonse.

Zothandiza kwa odwala omwe ali ndi mtundu II matenda a shuga a "Viktoza" amadziwika ndi madokotala.

Kuchepetsa thupi kumachitika chifukwa cha kuphatikiza kwa ntchito za kapamba, kuchepa kwa shuga m'magazi ndi kuchepa kwa chakudya. Mankhwala amathandizira kupanga maselo a beta.

Mphamvu ina ya mankhwalawa imachepetsa kukula kwa matenda ashuga. Zotsatira pambuyo pakukonzekera mankhwala mthupi zimawonedwa tsiku lonse.

Madzi a mayamwidwe amapezeka pang'onopang'ono, pokhapokha maola 8 mpaka 6 pazomwe amachititsa kuti magazi azigwira.

The bioavailability wa mankhwalawa ndi 55%. 98% ya izo imagwirizana ndi mapuloteni amwazi. Tsiku lonse, liraglutide imakhalabe m'thupi osasinthika. Hafu ya moyo wa mankhwalawa ndi maola 13.

Chizindikiro ndi contraindication

Mankhwala "Victoza" (malangizo ndi kuwunika akuwunikira za kufunsa kwa dokotala musanagwiritse ntchito mankhwalawa) amalembera mtundu wachiwiri wa matenda a shuga.

Pankhaniyi, yankho likhoza kugwiritsidwa ntchito limodzi ndi monotherapy komanso ndi chithandizo chovuta ndi othandizira pakamwa hypoglycemic, monga Dibetolong, Glibenclamide ndi Metformin.

"Victoza" wina ungagwiritsidwe ntchito popanga zovuta ndi insulin, ngati kugwiritsa ntchito mankhwala osakanikirana kale sikunapeze zotsatira.

Pazonse zomwe takambirana pamwambapa, chithandizo chamankhwala chiyenera kutsagana ndi zakudya zochizira komanso masewera olimbitsa thupi.

Mankhwala ndi oletsedwa kugwiritsidwa ntchito mwa mtundu woyamba wa matenda a shuga, komanso ngati pali Hypersensitivity pamagawo a mankhwalawa.

Simungathe kugwiritsa ntchito mankhwalawa panthawi yapakati komanso panthawi yoyamwitsa. Contraindication kuti agwiritse ntchito ndi ketoacidosis, colitis, mtima kulephera ndi paresis ya gastric organ.

Sikulimbikitsidwa kusankha "Vicose" kwa anthu ochepera zaka 18.

Mankhwala "Victoza": malangizo ogwiritsira ntchito

Mankhwalawa amaperekedwa kamodzi patsiku, subcutaneally, pamimba, phewa kapena ntchafu, osasamala chakudyacho. Ndikulimbikitsidwa kuti mupeze jakisoni ndi mankhwala a Victoza (malangizo omwe angagwiritsidwe ntchito amafotokozera mwatsatanetsatane njira yogwiritsira ntchito mankhwalawa) nthawi yomweyo. Mankhwalawa sangathe kugwiritsidwa ntchito pakuwongolera makonzedwe amtsempha makamaka pakhungu la intravenous.

Mlingo woyambirira watsiku lililonse wa wothandizirawu suyenera kupitirira 0,6 mg. Pang'onopang'ono, kupitirira sabata limodzi, amawonjezeredwa ku 1.2 mg. Ngati ndi kotheka, ndiye kuti pamasiku 7 otsatirawa, onjezerani pang'onopang'ono mlingo mpaka 1,8 mg. Mlingo wa tsiku ndi tsiku wa 1.8 mg ndiwovomerezeka kwambiri.

Madokotala amalangiza Victoza yankho kuti athandizire chithandizo cha metformin. Ndikulimbikitsidwa kuti muzigwiritsa ntchito limodzi ndi metformin ndi thiazolidinedione. Mlingo wa mankhwala aposachedwa sangasinthidwe.

Mankhwalawa amagwiritsidwa ntchito pochiza sulfonylureas komanso mankhwalawa a metformin okhala ndi sulfonylureas. Potsirizira pake, zomwe zili sulfonylurea zotumphukira zimachepetsedwa kuti zisachitike mwadzidzidzi hypoglycemia.

Apa, kusankha kwa mankhwalawa sikofunikira kutengera zaka za wodwalayo. Mosamala, Victoza akuyenera kugwiritsidwa ntchito ndi anthu azaka 75 wazaka zopitilira.

Ndi chovomerezeka kugwiritsa ntchito mankhwalawa popanda kusintha kwa odwala omwe ali ofatsa pang'ono komanso ochepa. Woopsa pathologies a impso ntchito, mankhwalawa ndi contraindicated. Komanso, mankhwalawa sayenera kuperekedwa kwa anthu omwe ali ndi matenda a impso osiyanasiyana.

Zotsatira zoyipa

Mankhwala "Victoza" (ndemanga amati mankhwalawa ndi okwera mtengo, koma amagwira ntchito moyenera ndipo zotsatira zake ndi zabwino) atagwiritsidwa ntchito, amatha kuyambitsa nseru, kusanza Reflex, kutsegula m'mimba komanso kupweteka m'matumbo. Pakukonzekera mankhwalawa, kuchepa kwa chidwi cha kudya ndi matenda a anorexia kumawonedwa nthawi ndi nthawi. Kugwiritsa ntchito molakwika mankhwala kungayambitse vuto la mutu, mutu.

Pali mwayi wa kusapeza bwino pamalowa. Nthawi zina, mankhwalawa amakhumudwitsa matenda opatsirana a chapamwamba kupuma thirakiti.

Mosamala, muyenera kugwiritsa ntchito mankhwalawa pancreatitis, popeza kuchulukitsa kwake ndikotheka. Nthawi zina, kugwira ntchito bwino kwa chithokomiro kumachitika. Chipangizochi chimatha kupangitsa kuti khungu lizipezekanso ndi ma neoplasms ena.

Ngati zizindikiro zomwe zili pamwambazi zikuchitika, kugwiritsa ntchito Victoza kuyenera kusiyidwa.

Mankhwala "Victoza": ndemanga ya odwala ndi madokotala

Madokotala onse, kupatula, amawona kuti mankhwalawa ndi akulu ndikulimbikitsa kuti mugwiritse ntchito mosamalitsa monga momwe akuwonera, komwe ndi pamaso pa mtundu II matenda a shuga. Pokhapokha ngati izi, chithandizo ndi wothandizirayi ndi chomwe chidzapatse zotsatira zabwino, chifukwa kunenepa kwambiri kumapangitsa gawo lalikulu pano.

Mankhwala omwe amagwiritsidwa ntchito pazolinga zake amaletsa kukula kwa matenda ashuga komanso zovuta zake. Mothandizidwa bwino shuga ndi kubwezeretsa zachilengedwe kupanga insulin. Victoza amayambitsa chidwi ndi njala.

Odwala ena adatha kutsika mpaka 8 kg pa mwezi. Madokotala amachenjeza kuti mankhwalawa sayenera kuperekedwa nokha ndipo muchepetse thupi basi.

Zimatha kuyambitsa khansa ya chithokomiro komanso zimayambitsa mawonekedwe a pancreatitis pachimake. Kugwiritsa ntchito mosagwiritsa ntchito Victoza.

Ndemanga za iwo omwe achepetsa thupi ndi zosiyana kwambiri. Oipa amati kuchepa thupi pang'ono, makilogalamu 1-3 pamwezi.

Kuwonongeka kwa thanzi, kusokonezeka kwa metabolic, kupweteka pamutu ndi kudzimbidwa kumadziwika.

Sakuwona kufunika kokagulanso, chifukwa mukufunikirabe kutsatira kadyedwe ndikuyang'anira kulimba. Monga lamulo, anthuwa adagwiritsa ntchito mankhwalawa popanda mankhwala a dokotala komanso popanda umboni wapadera.

Zotsatira zabwino za mankhwala "Viktoza" a odwala omwe ali ndi matenda amtundu II. Anthu awa amawonetsa kuchepa kwakukulu, makilogalamu 8-15 pamwezi.

Zinali zotheka kukwaniritsa izi osati kokha ndi mphamvu ya mankhwalawo pathupi, komanso ndi chakudya choyenera komanso zolimbitsa thupi.

Odwala amawonetsa kupepuka mthupi lonse, kusintha kwa mtima wamagazi, kuchepa kwa chakudya ndi kuchepa kwa ma kilogalamu osafunikira. Anthuwa adakhutira ndikuyenda bwino kwa yankho la Victoza.

Ndikulimbikitsidwa kuti mankhwalawa "Viktoza" agwiritsidwe ntchito mosamalitsa monga adanenera. Ma analogu ndi mankhwala omwewa sangathe kulembedwa pawokha, popanda kuwunika, chifukwa zotsatira zake zimakhala zomvetsa chisoni kwambiri.

Ngati mankhwalawa "Victoza" sanakwane ndikuyambitsa zovuta, ndiye kuti angathe kuthana ndi mankhwalawa, monga "Saksenda" ndi "Baeta". Loyamba likufanana ndi "Viktoza" pankhani ya zinthu zomwe zimagwira. Zimawononga ma ruble 27,000.

Lachiwiri lilinso ndi chinthu china, koma limafanana ndi momwe limakhudzira thupi ndi zisonyezo. Mtengo wake ndi wozungulira ma ruble 4,500.

Mtengo wa mankhwala

Mankhwala "Victoza" amatanthauza mankhwala okwera mtengo (ndemanga za madokotala amazindikira kufunika koyezetsa thupi lonse musanagwiritse ntchito chida ichi). Mtengo wake mu cholembera cha 3 ml syringe No. 2 umasiyana m'chigawo cha rubles 3,000. Mankhwalawa amagulitsidwa m'mafakisoni wamba ndipo amaperekedwa kokha mwa mankhwala.

Njira yothetsera Victoza ndiyofunikira kwa anthu odwala matenda ashuga a II, koma anthu ena onse azigwiritsa ntchito mosamalitsa monga momwe zalembedwera.

Ndemanga za Viktoza madotolo

• imakhazikitsa kuchuluka kwa ma peptides ofunikira,
• Amasintha mkhalidwe ndi ntchito za kapamba,
• amachepetsa shuga
• Imachepetsa chimbudzi,
• thupi limatenga michere yambiri pazakudya zomwe zatha, zomwe kwa nthawi yayitali zimapanga
• kumva kuti mukusunthika komanso kumachepetsa njala,
• amachepetsa kuchuluka kwamafuta.

Kafukufuku wasonyeza kuti mankhwalawa ndi othandiza kwambiri pakuchepetsa thupi komanso kulimbana ndi kunenepa kwambiri, makamaka akaphatikizidwa ndi zakudya komanso masewera. Mlingo wosankhidwa bwino wa mankhwalawo ndiwosavulaza, komabe, musanagwiritse ntchito mankhwalawa, simuyenera kunyalanyaza zonena zanu ndi kufunsa dokotala.

Kulembetsa kusiya kubwereza.

Zimatenga mphindi zosakwana 1.

Ndiyenera kunena nthawi yomweyo kuti mankhwala a Victoza sanandithandizire kuchepetsa thupi. Zotsatira zake ndikugwiritsa ntchito ndizochepa. Ndikuganiza kuti kudziwongolera nokha kuti muchepetse thupi sikuchepetsa thupi, chifukwa mankhwalawa samapereka chitsimikizo, pomwe ali ndi zovuta komanso zotsutsana.

Mankhwalawa ali ndi mawonekedwe achilendo otulutsidwa - cholembera. Voliyumu yazomwe zili ndi 3 ml, mlingo wa zomwe zimagwira ndi 18 mg. Mu phukusi limodzi - 2 ma PC. The yogwira pophika mankhwala ndi liraglutide ndi sodium hydrogen phosphate dihydrate. Njira yothetsera vutoli ndi yopanda utoto, yowonekera konse.

Mtengo ndi wokwera mtengo - phukusi limodzi limatengera 9 mpaka 10 rubles. Mankhwalawa amapakidwa paphewa kapena m'mimba. Poyamba, mlingo sayenera kupitirira 0,6 mg. Pambuyo kuchuluka kwa 1.8 mg. Mlingo wofunikira uyenera kuwonetsedwa pogwiritsa ntchito sinthani ya syringe. Mukamachepetsa thupi, tikulimbikitsidwa kupaka jekeseni osachepera.

Dokotala wanga wa endocrinologist adandiuza Viktozu kuchuluka kwanga kwa shuga m'magazi. Kuphatikiza apo, adandipatsa chakudya chamafuta osapatsa mphamvu komanso masewera olimbitsa thupi.

Zinali zowopsa kupanga jakisoni m'mimba poyamba, koma zenizeni sizinthu zonse zowopsa: syringe ndi yabwino kwambiri, chinthu chachikulu ndikutsatira malangizowo ndikutsatira malamulo onse musanalowe.

Mlingo woyamba womwe adotolo adandiuza anali 0,6 mg yokha, ndi 0,1 ml yankho lokha - panthawi yomwe jekesayo samamveka konse, jekeseni wa singano yekha, koma ndi yochepa komanso yochepa thupi, imayambitsa kupweteka pang'ono. Jakisoni amayenera kuchitidwa kamodzi patsiku, atatha jakisoni 10, Mlingo wanga unakulitsidwa 1 mg.

Patatha mwezi umodzi, kulemera kunatsika ndi 5 kg, shuga inatsika mpaka 5.7. Ndazindikira kuti poyamba ndimakhala ndi vuto la mseru, ndipo ndimasanza kangapo, adandifotokozera kuti izi zidachitika chifukwa cha kufulumira kwa magazi. Ngakhale kuti majakisoni sanali opweteka, ndimawakumbukira zowopsa, njirayo imakhala yosasangalatsa.

Anandisankhira maphunziro a Victoza: sabata yoyamba pa 0,6 mg, ndipo wachiwiri ndi 1.2 mg. Panthawi imeneyi, kulemera kwake kunachepa ndi 7 kg. Kudya sikunali bwino, kwa tsiku lomwe ndinadya saladi wa masamba ndi chidutswa cha nkhuku yophika.

Ndinkamva mavuto: Nthawi zonse ndimadwala, ndimakonda kusanza, kutopa, kufoka, komanso kusachita chidwi.

Pomaliza milungu iwiri iyi idatha ndipo ndimadutsa mayeso obwereza, zotsatira zake zinali zokhumudwitsa - shugayo adatsika kwambiri mwanjira yovomerezeka, ndipo mahomoni omwe ndimakhala nawo nthawi zonse anali abwinobwino, amangodutsa padenga.

Zinadziwika kuti Viktoza ndi mankhwala osokoneza bongo, omwe amapanga kwambiri ndi Liraglutid - analog of GLP-1.

Pansi pa GLP-1 iyi, dzina la enteroglucagon, mahomoni a peptide kuchokera ku banja la incretin, amasungidwa. Mankhwala a Hormonal ndi owopsa kwambiri, zochita zawo sizikudziwika ndipo ndizosatheka kuzigwiritsa ntchito pakuchepetsa thupi.

Inde, ndinachepa thupi, koma ndili ndi zilonda zosasangalatsa zomwe ndakhala ndikuchita kwa nthawi yoposa chaka.

Ndimaika Viktoze mfundo zitatu, chifukwa zimathandiza ndi matenda ashuga komanso matenda a shuga ndimagazi, koma njira yochepetsera thupi ndi yosavomerezeka. Amalonjeza kuti chisangalalo chidzachepa, kugaya chakudya kumachepetsa ndipo zinthu zopindulitsa zokha ndi zomwe zingalowe mthupi, ndipo kuchuluka kwa minofu yamafuta m'thupi kumachepa.

Tengani mankhwalawa kamodzi patsiku molingana ndi insulin. Ndi syringe yapadera, mumatenga madzimadzi olondola ndikubaya paphewa lanu.

Njirayi ndi yosavuta, yofotokozedwera mu malangizo mwatsatanetsatane, singano yotayidwa imalumikizidwa ndi syringe. Phukusi la ma servings 30, izi ndi za mwezi umodzi, ndipo sindinafune zina. Adalonjeza kuchuluka kwa kilogalamu 7. Ndinagwetsa 2, kenako - chifukwa chopita ku masewera olimbitsa thupi.

Ndikudziwa izi motsimikiza, chifukwa chilakolako changa cha chakudya sichinasinthe, ndimadya monga momwe zimakhalira kale.

Maphunziro a Victoza adakonza mwezi umodzi. Zotsatira zake zidalidi, koma, monga momwe ndikuwonekera kwa ine, sizinali zamankhwala, koma kuchokera pakulaka kofunitsitsa kuti muchepetse kulemera kwenikweni. Kwa mwezi umodzi ndidapeza kilogalamu 1, izi ndizothandiza kwa ine, ngakhale wopanga adalonjeza pafupifupi 7 kg.

Mukamamwa Victoza, ndinamva kuchepa kwa chikhumbo, ichi ndi chowonjezera kwa ine. Zikuwonekeratu kuti magawo anga azakudya adatsika moyenerera. Ndikuganiza kuti Viktoza amachepetsa shuga m'magazi, chifukwa chake kuchepa kwa chikhumbo. Chifukwa chake, zidzakhala zothandiza kwambiri kwa odwala matenda ashuga, koma kwa iwo omwe akuchepetsa thupi - sindikukulangizani.

Malangizo achidule ogwiritsira ntchito, contraindication, kapangidwe

• Mitundu 2 ya shuga mellitus 2, kuphatikiza ndi Glibenclamide, Dibetolong, Metformin.

• Ngati kuphatikiza kwa mankhwala am'mbuyomu sikuthandiza, ndiye kuti muziphatikiza ndi insulin.

• Mtundu umodzi wa matenda ashuga

• Mimba, nthawi yoyamwitsa,

• Mavuto am'mimba (colitis, paresis),

• Kuwonongeka kwa chiwindi, impso,

• Kusateteza kwayekha pazigawo za mankhwala.

Njira yogwiritsira ntchito (mulingo)

Mankhwalawa amagwiritsidwa ntchito kamodzi pa maola 24 mu mawonekedwe a jekeseni mosavomerezeka mu femur, phewa kapena pamimba. Kumayambiriro kwa mankhwalawa, mlingo uyenera kuchepetsedwa, pafupifupi 0,6 mg patsiku, kenako umakwera mpaka 1.8 momwe mungathere. Mlingo woyenera ndi 1,2 mpaka 1.4 mg.

Nthawi zina, Viktoza amaphatikizidwa ndi mankhwala ena, mlingo uyenera kukambirana ndi dokotala. Magazi a odwala nthawi ndi nthawi amatengedwa kuti awunikidwe.

Malangizo apadera (machenjezo)

Kafukufuku akuwonetsa kuti chithandizo cha Victoza panthawi yoyembekezera komanso yoyamwitsa chimakhala ndi vuto, motero sikulimbikitsidwa kugwiritsa ntchito mankhwalawa panthawiyi.

Kuwonongeka kwakanthawi kochepa, komanso matenda a kapamba. Pakhala pali zochitika za pancreatitis pachimake. Pankhaniyi (kupweteka kwambiri m'mimba m'mimba), chithandizo ndi mankhwalawa chimayimitsidwa nthawi yomweyo.

Mukamayesedwa kugwiritsa ntchito mankhwalawa, kusokonezedwa pakugwira ntchito kwa chithokomiro kumadziwika. Mitundu yosiyanasiyana, Goiter, kuwonongeka mu mayeso a hormone ndikotheka. Makamaka muyenera kusamala ndi odwala omwe anali kale ndi vuto la chithokomiro.

The zimachitika mseru, kusanza pachimake. Mankhwala ayenera kusiyidwa, chithandizo chikuyenera kukhala chazizindikiro.

Amapangidwa ngati njira yothetsera jakisoni wa subcutaneous.

Zisungidwe: Ziyenera kusungidwa mufiriji, moyo wa alumali sizoposa zaka 2.5.

Malangizo / ndemanga za madotolo: tili ndi gawo lalikulu la zokambirana patsamba lathu, komwe mankhwala a Victosa amakambirana ka 2 ndi odwala ndi madokotala - onani

Ndemanga za Odwala

Kodi ndizingati ku Israeli?

inde zilipo. Fungo lofanana ndi fungo la insulin. aukali komanso osasangalatsa.

Tsopano ndimagwiritsa ntchito ngati "ambulansi", yokhala ndi kususuka kwa nthawi yayitali, mu kipimo cha 1. 8.

Ndimamuseka usiku, koma ndikuganiza kuti zikhale za tsikulo, ndiye kuti kuchepa kwake kumachepa. Kuphatikiza ndi Siofor

Katundu Wocheperako

Victoza nthawi zambiri amagwiritsidwa ntchito pakuchepetsa thupi ngati palibe matenda ashuga kapena matenda ena amtundu wa endocrine.

Izi ndichifukwa choti, motsutsana ndi maziko akumene kuchepa kwa milingo ya glycemia, kutaya kwa m'mimba kumachepera.

Chithandizo chogwira ntchito chimathandiza kuchepetsa thupi. Mafuta amatsitsidwa mwachilengedwe, ndipo zida zonse zomwe zimakhudzidwa ndi njirayi sizitha kuvulaza thupi. Kutentha kwamafuta kumachitika pochepetsa njala komanso kuchepetsa mphamvu zamagetsi.

Mankhwala Victoza kapena Saksenda (dzina lina la mankhwalawo lomwe cholinga chake nkulimbana ndi onenepa kwambiri mwa odwala omwe alibe matenda ashuga) amaperekedwa kwa odwala kuti azitha kukhazikika ndikuwongolera mndandanda wa glycemic. Kuyeserera ndi mankhwalawa sikuyenera - musanagwiritse ntchito ndikofunikira kwambiri kuti muthandizidwe ndi akatswiri othandizira kapena azolimbitsa thupi.

Zokhudza matenda asanakwane shuga

Monga kafukufuku wa nyama zomwe zili ndi prediabetes states akuwonetsa, liraglutide amachepetsa kupangika kwa matenda a shuga. Mwanjira zambiri, zotsatira zabwino zimachitika chifukwa cha kuchuluka kwa ma cell a beta. Mwachidule, chiwalo chimachira msanga, ndipo njira zakukonzanso zimapambana njira zowonongeka.

Udindo wofunikira umachitidwa ndi kutetezedwa kwa zinthu zakumaso ku zinthu zingapo zovuta:

• Kukhalapo kwa cytotoxins
• Kukhalapo kwa mafuta achilengedwe aulere omwe amayambitsa kufa kwa maselo a beta a gland.
• Maselo olemera ochepa am'mimba, zomwe zimatsogolera thupi.

Zolemba za Pharmacokinetic

The kuyamwa kwa yogwira pang'onopang'ono, zomwe zimatsimikizira kukhalitsa kwa thupi.

Kuchuluka kwa plasma ndende kumachitika maola 8 mpaka 10 pambuyo pa kuperekera mankhwala.

Liraglutide amawonetsa kukhulupirika kwa odwala azaka zonse ndi magulu. Kafukufuku pomwe odzipereka kuyambira wazaka 18 mpaka 80 adatenga nawo zotsatirapo zotsimikizira izi.

Zisonyezo za kumwa mankhwalawa

Victoza, monga mawonekedwe ake, amawonetsedwa kwa odwala onse omwe ali ndi matenda ashuga a 2. Kutengera zakudya zoyenera komanso kuchita masewera olimbitsa thupi nthawi zonse, mankhwalawa amawonetsa kugwira ntchito bwino. Malinga ndi ndemanga za odwala, Victoza amakulolani kuwongolera chisonyezo cha glycemic, mosasamala kanthu za mawonekedwe a anamnesis ndi machitidwe ake.

Pali malo angapo osankhidwa a Victoza. Kuyang'ana kwa madokotala kuli ndi chiyembekezo chogwirizana ndi aliyense wa iwo:

1. Monotherapy (Viktoza m'modzi yekha mwa cholembera cha syringe amaperekedwa kuti azilamulira anthu omwe ali ndi matenda ashuga komanso kukhazikika kwa odwala omwe ali ndi vuto la chakudya chambiri).
2. Kuphatikiza mankhwala ndi mankhwala amodzi kapena angapo a hypoglycemic omwe amatengedwa pakamwa. Nthawi zambiri timalankhula za metformin ndi urea sulfinyl. Njira yochizira iyi ndiyothandiza kwa odwala omwe sanathe kukwaniritsa kuwongolera kuzowonetsa kwa glucose m'mbuyomu zochizira zam'mbuyomu.
3. Mankhwala ophatikizika ozikidwa pa insal insulin mwa odwala omwe sanamve zotsatira zoyenera akamagwiritsa ntchito mankhwalawa malinga ndi chiwembu chomwe chatchulidwa pamwambapa.

Zokhudza contraindication

Mtengo wovomerezeka wa Victoza ndi ndemanga zabwino zimapangitsa kuti mankhwalawa atchuka kwambiri. Komabe, ngakhale chitetezo chokwanira, njira yabwino yopangira mankhwala komanso kugwiritsa ntchito kwa onse mankhwala kwa odwala onse sikuti chifukwa chakuyiwala za contraindication:

1. Hypersensitivity to Victoza zigawo, mosasamala kanthu za wopanga (izi ndi zotsutsana mwanjira iliyonse, zogwirizana ndi mankhwala aliwonse amtundu wa mankhwala),
2. Mbiri ya khansa ya chithokomiro ya mtundu wotsika mtengo (ngakhale mbiri ya banja),
3. Neoplasia wa endocrine chiyambi (zingapo)
4. Kulephera kwakukulu kwaimpso,
5. Kulephera kwa chiwindi,
6. Kulephera kwa mtima I - kalasi yogwira ntchito II.

Magulu apadera

Victoza, malinga ndi ndemanga, amakhala ngati mankhwala otetezeka komanso othandiza kwambiri. Komabe, pali mikhalidwe ina momwe sizingatheke kupatsa mankhwala mankhwala, popeza munthawi zina zinthu zomwe sizigwira ntchito sizigwira ntchito.

Tikulankhula za ma pathologies otsatirawa ndi mikhalidwe yapadera:

• Mtundu wa shuga wa mtundu woyamba,
• Ketoacidosis wodwala matenda ashuga,
• Mimba
• Kuchepetsa
• Kutupa kwa mucosa ya m'mimba yaying'ono kapena yayikulu,
• Zaka zosakwana zaka 18 (palibe chidziwitso pakuvomerezeka, popeza maphunziro omwe adachitika mwa odwala omwe sanakwanitse zaka zambiri sanachitepo),
• Gastroparesis wa mtundu wa matenda ashuga.

Zotsatira zoyipa

Maphunziro azachipatala a mankhwalawa akhala akuchitika mobwerezabwereza. Akatswiri adatha kuphunzira zonse zoyipa za Victoza. Monga mankhwala ena aliwonse, liraglutide yokhazikika yodwala imatha kuyambitsa mavuto. Mutha kudziwa zambiri pokhudzana ndi kusakhudzika kwa thupi powerenga zambiri zomwe zili patebulopo.

Zokhudza kuphatikiza kwa mankhwala

Wowonongera amachepetsa mphamvu ya digoxin mukamamwa mankhwalawa nthawi imodzi. Zofananazo zimawonedwa limodzi ndi lisinopril.

Mankhwala amatha kuphatikizidwa mosamala ndi mankhwala a antihypertensive, mapiritsi oletsa kubereka a mahomoni.

Malinga ndi ndemanga za madotolo, Viktoza wochepetsa thupi ayenera kumwedwa mosamala kwambiri osapatsidwa mankhwala ena omwe angakhudze kuchuluka kwa shuga mthupi.

Njira zotengera Victoza

Mankhwalawa amaperekedwa ngati jekeseni wothira kamodzi patsiku. Kukhazikitsidwa kwa mankhwalawa sikumangidwa pazakudya zambiri. Ngati mukuvutika ndi jakisoni, mutha kudziwa momwe mungagwiritsire ntchito syringe ndi cholembera ndi Viktoza kuchokera kwa dokotala.

Chidacho chimagulitsidwa nthawi zonse pamiyeso yokhazikika komanso syringe, yabwino kugwiritsidwa ntchito nthawi iliyonse. Victoza akhonza kuyikika pa "mfundo" zotsatirazi:

Ngati ndi kotheka, madera omwe mankhwalawa amaperekedwa, komanso nthawi ya jakisoni, amatha kusintha molingana ndi wodwala. Zotsatira zonse zochizira sizingasinthe. Mankhwala ndi osavomerezeka ntchito kwa mtsempha wa magazi.

Mlingo woyamba sayenera kupitirira 0,6 mg yogwira mankhwala patsiku. Pakati pa sabata yoyamba, mulingo wocheperako ungathe kuwonjezeka pang'onopang'ono mpaka 1.2 mg. Mtengo wokwanira wololedwa pamilandu yapadera ndi 1.8 mg pa kugogoda.

Momwe mungasungire syringe

Mankhwala amaperekedwa mu mawonekedwe a yankho (6 mg mu 3 ml yamadzimadzi), woyikidwa mu cholembera chosavuta. Algorithm yogwiritsira ntchito mankhwala opangidwa ndi mankhwala ndi motere:

1. Chipewa choteteza chimachotsedwa mosamala mu syringe.
2. Kuchokera singano yotayika chotsani pepala.
3. Singano ili bala pa syringe.
4. Chotsani kapu yoteteza ku singano, koma osayitaya.
5. Kenako ndikofunikira kuchotsa singano ya kapu wamkati (pansi pake ndi singano).
6. Kuyang'ana thanzi la syringe.
7. Chogwirira chimakola mozungulira, kusankha mlingo. Chizindikiro cha mlingo uyenera kukhala wofanana ndi chekeni.
8. Srinjiyo imakokedwa ndi singano kumtunda, ndikukwapula mokoma cartridge ndi chala cholozera. Kudzinyenga ndikofunikira chifukwa kumakupatsani mwayi kuthamangitsa thovu lomwe limapeza mu yankho.
9. Syringe imayenera kumakonzedwa m'malo mwa "singano" ndikanikizidwa kuti “yambani” kangapo. Kudzimbidwa kumachitika mpaka "zero" utawonekera pachizindikirocho, ndipo dontho lamadzi liziwoneka kumapeto kwa singano.

Nthawi yomweyo jekeseni isanachitike, muyenera kuonetsetsa kuti mlingo woyenera wasankhidwa. Kupereka mankhwalawa, syringe imatembenuzidwa ndipo singano imayikidwa pansi pa khungu. Kanikizani batani loyambira pang'onopang'ono komanso pang'onopang'ono. Njira yothetsera vutoli iyenera kulowa pakhungu pakapita masekondi 5 mpaka 7.

Kenako singano imayamba kutulutsidwa pang'onopang'ono. Chipewa chakunja chimayikidwa. Ndizoletsedwa kukhudza singano ndi zala zanu. Kenako chinthucho chimasulidwa ndikuchotsedwa. Cholembera chimbale chokha chimatsekedwa ndi chipewa chapadera.

Lycumia ndi Victoza

Nthawi zambiri funso limabuka, pali kusiyana kotani pakati pa Lixumia ndi Victoza, omwe mankhwalawa amasankhidwa pomenyera kunenepa kwambiri komanso kuwonetsa matenda ashuga. Viktoza mu mtengo amatanthauza mankhwala ena okwera mtengo omwe ndizovuta kugula kuti muzigwiritsa ntchito tsiku lililonse. Ichi ndi chimodzi mwazifukwa zomwe akuyesera kuloweza mankhwala othandiza komanso otetezeka kwathunthu pogwiritsa ntchito njira zina.

Lixumia ndi mankhwala omwe amalembera mankhwalawa mtundu wa matenda ashuga a 2 kuphatikiza ndi metformin. Ngati Wopondera amawongolera kuchuluka kwa shuga ndi glucagon, ndiye kuti Lixumia amatha kugwira ntchito kumodzi mokha - posintha kuchuluka kwa shuga.

Kusiyananso kwina kwakukulu, komwe nthawi zina kumatha kuwonedwa ngati vuto lalikulu ndikubweretsa chakudya. Mankhwalawa amaperekedwa ola limodzi asanadye m'mawa kapena madzulo, zomwe sizikhala bwino nthawi zonse. Pankhani ya Victoza, jakisoni itha kuchitika nthawi iliyonse yabwino.

Mwambiri, zomwe zikuwonetsa, contraindication, kusungirako ndi magwiritsidwe a kukonzekera ndizofanana. Kope yopanga ya GLP imagwiritsidwa ntchito kuchepa thupi mu mono-achire regimens. Ponseponse, Liksumia ikhoza kusinthidwa ndi Viktoza, koma m'malo mwake simudzakhala chilungamo. Kwa magawo ambiri, mankhwalawa omaliza amakhala okongola kwambiri kuthetsa mavuto achire.

Baeta kapena Victoza: kusankha

Funso lina lodziwikiratu ndizomwe zili bwino kuposa Bayet kapena Viktoza. Baeta ndi amino acid aminopeptide. Amasiyana kwambiri mu chikhalidwe cha mankhwala kuchokera ku Victoza wogwira ntchito, koma amatsimikizira kwathunthu mankhwalawa. Pofufuza "Victoza yaulere," aminopeptide sangatchulidwe njira yabwino kwambiri. Zimatenga ndalama zoposa mankhwala zochokera liraglutide.

Komabe, pali zosiyana zomwe zikuyenera kulipira chisamaliro chapadera. Mankhwala a Baeta amafunika kuperekedwa kawiri pa tsiku.

Patangotha ​​ola limodzi, munthu ayenera kugona pansi, ndipo mankhwalawo amapaka jekeseni pansi pakhungu pang'onopang'ono.

Ichi ndi lingaliro lofunikira lomwe liyenera kukumbukiridwa posankha chithandizo chachikulu cha odwala omwe ali ndi matenda a shuga a 2.

Victoza ndi wotsika mtengo kuposa Baeta, ndipo imayambitsidwanso mosavuta.

Kukhazikitsa aminopeptide m'malo mwa liraglutide ndi kofunikira pokhapokha thupi la wodwalayo litaona chithandizo ndi mankhwala okwera mtengo kwambiri, kunyalanyaza Victoza.

Viktoza ndi mowa

Kuphatikiza kwa mankhwala aliwonse a mankhwala ndi mowa nthawi zambiri sikuyenera. Kwa odwala matenda ashuga, momwe amapangira matendawa ndi gawo limodzi lamoyo. Muyenera kuthana ndi glucose wosakhazikika nthawi zonse, zomwe zikutanthauza kuti muyenera kumadziletsa zakudya komanso zakumwa zoledzeretsa.

Zakumwa zoledzeretsa za mtundu 2 za shuga zimachitika makamaka. Kumwa mowa kumatha kudzetsa kuti wodwalayo adzakumana ndi zizindikiro za hypoglycemic - kuchuluka kwa glucose m'magazi kumatsika kwambiri.

Izi zimadziwika makamaka ngati mowa umamwa pamimba yopanda kanthu, ndi chakudya chochepa, kapena kuchuluka kwa mowa palokha kumakhala kosangalatsa.

Zinthu zilizonse zokhala ndi mowa zimathandizira kuti pakhale mankhwala okhala ndi insulin ndi mapiritsi omwe amachepetsa insulin. Kuphatikiza apo, zinthu zingapo zomwe zili ndi zakumwa zimakhudzanso chiwindi - zimachepetsa kaphatikizidwe ka shuga.

Kuopsa kwa hypoclycemia (ngakhale mpaka kukomoka kwa hypoglycemic) kumakulirakonso, ngati, atamwa mowa ndi kudziletsa pakudya, wodwalayo amakumana ndi zovuta zolimbitsa thupi. Ndi zoletsedwa kumwa mitundu yayikulu yamadzulo madzulo ndikupereka mankhwala aliwonse kuti muchepetse shuga. Ngati muli m'tulo, vuto linalake lalikulu kwambiri la hypoglycemia limayamba.

Ngakhale mankhwala a Victoza amadziwika ndi mtundu wapadera wamankhwala ndipo "mwanzeru" amawongolera njira zonse mthupi, munthu sayenera kuyiwala kuti kuphatikiza kwa mankhwala ndi mowa kumakhala koopsa.

Malangizo apadera

Chithandizo cha liraglutide njira limodzi ndi kuvomerezedwa kwa piritsi kukonzekera, kudya ndi zolimbitsa thupi. Kupanda kutero, chithandizo chamankhwala chimakhala ndi zotsatira zopanda mphamvu komanso zosakhazikika.

Mlingo woikidwa suyenera kupitilira, ndipo mankhwalawo sayenera kugwiritsidwa ntchito pazifukwa zina, mwachitsanzo, mankhwalawa a matenda amtundu 1 kapena pofuna kuwongolera kunenepa kwambiri. M'nthawi zonsezi, zovuta zomwe sizingachitike ndizotheka.

Nutritionists salimbikitsa kugwiritsa ntchito subcutaneous dongosolo la hypoglycemic wothandizira kwa anthu omwe ali onenepa kwambiri ndi etiology yosadziwika.

Ngakhale mtengo wokwera, Viktoza ndiwodziwika pakati pa odwala matenda ashuga, koma kuti mupeze zotsatira zomwe mukufuna popanda zotsutsa, muyenera kutsatira malangizo ogwiritsa ntchito. Tiyeneranso kudziwa kuti Viktoza ali ndi vuto lambiri (izi ziyenera kukumbukiridwa ndi mankhwala a antidiabetesic).

Kuphatikiza kwa mowa ndi Viktoz sikovomerezeka, popeza mowa wa ethyl umawononga maselo achisamba, kuchepetsa chinsinsi chawo. Kuphatikiza apo, odwala matenda ashuga ayenera kukhala ndi moyo wathanzi, kukana, pakati pazinthu zina, kumwa mowa.

Zotsatira zoyipa

Therapy yokhala ndi liraglutide imayendera limodzi ndi kutukuka kwa zoyipa kuchokera m'matumbo ndi mitsempha ya m'mimba. Mwina kuwoneka kusanza, nseru, kutsekula m'mimba kapena kupweteka m'mimba pambuyo pakukonzekera kwa mankhwalawa. Mutu ndi chizungulire sizimalamulira. Zowonekeranso:

• achina,
• zolimbitsa mphamvu zapakati
• kuchepa kapena kusowa kwa chakudya,
• kunenepa kwambiri
• thupi lawo siligwirizana pa malo jakisoni.

Ndizachilendo kwambiri (koma osaphatikizidwa) kuti pali zovuta kupuma komanso matenda opatsirana thirakiti.

Ndemanga za Viktoza

Kutulutsa Fomu: Yankho la subcutaneous makonzedwe

Irina (ndemanga zabwino)

Kuonda msanga.

Anandipeza ndi matenda a endocrinological omwe amalumikizidwa ndi vuto la chithokomiro. Adotolo adati choyamba muyenera kuchepetsa thupi, ndipo jekeseni wa Viktoza adayikidwa m'mimba. Mankhwalawa amamuunjikira cholembera, cholembera chimodzi chimakhala pafupifupi mwezi ndi theka. Mankhwalawa amalowetsedwa m'mimba.

M'masiku oyambilira jakisoni anali kudwala kwambiri ndipo samatha kudya kalikonse. Mwezi woyamba zidatenga ma kilogalamu 15, ndipo wachiwiri winanso 7. Mankhwalawa ndi othandizadi, koma chithandizo chitha ndalama zambiri. Thupi litazolowera, mavuto sanawonekere.

Ndikwabwino kutenga singano zazifupi za jakisoni, chifukwa zilonda zimakhalabe zazitali.

Alexandra (kusawerengera)

Mankhwalawa ndi okwera mtengo kwambiri, ndipo mkatikati mwake muli ma syringe atatu okha. Koma ali omasuka mosaganizira - mutha kudzipangira nokha jakisoni, kulikonse. Ndidagwira jakisoni m'chafu, singano ya syringe ndi yapamwamba kwambiri, yopyapyala, padalibe kupweteka.

Mankhwalawo pawokha, akaperekedwa, samapatsanso ululu, ndipo koposa zonse, Victoza ali ndi chidwi chodabwitsa. Shuga wanga, yemwe ngakhale akugwiritsa ntchito mankhwala atatu sanatsike ndi 9,7 mmol, tsiku loyamba la chithandizo ndi Viktoza adatsikira ku 5.5 mmol ndipo adakhalabe tsiku lathunthu.

Panali zovuta panthawi yomweyo, ndinali kudwala tsiku lonse, koma patatha masiku angapo nditagwiritsa ntchito mankhwalawa zidatha. Komabe, nditatha milungu iwiri ndi theka ndikugwiritsa ntchito Victoza, adanditenga ndi ambulansi yomwe inali ndi ululu wam'mimba kwambiri. Dokotala atapezeka ndi pancreatitis yovuta kwambiri, zinakhala zovuta za Viktoza.

Kalanga ine, ndinayenera kumusiya chifukwa cha izi.

Olesya (ndemanga zotsutsa)

Mankhwala okwera mtengo kwambiri

Ndikudziwa kuti mankhwalawa ndiwotchuka kunja. Anthu omwe ali ndi matenda ashuga akuigula ndi bang, chifukwa opanga sachita manyazi ndi kuchuluka. Amawononga ma ruble 9500. kwa syringe imodzi yomwe imakhala ndi 18 mg ya liraglutide. Ndipo izi ndizabwino kwambiri, m'misika ina 11,000 amagulitsidwa.

Zomwe ndizomvetsa chisoni kwambiri - sindinasinthe Viktoza. Mulingo wa shuga wamagazi sunatsike ndipo kulemera kwake kunakhalabe pamlingo womwewo. Sindikufuna kutsutsa omwe amapanga mankhwala chifukwa chosakwanira bwino pazinthu zawo, pali ndemanga zambiri zabwino za izo, koma ndili nazo monga choncho. Sizinathandize.

Zotsatira zoyipa zimaphatikizapo nseru.

Anyuta (ndemanga zabwino)

Kupulumutsidwa ku matenda ashuga

"Victoza" adandipatsa kuchipatala koyamba. Kufufuzako zingapo kunapangidwanso kumeneko, kuphatikizapo matenda osokoneza bongo, ziphuphu zakumaso, kunenepa kwambiri, komanso kuperewera kwa ubongo. Amayika "Victoza" kuyambira masiku oyamba, jakisoni amapangidwa m'mimba. Poyamba, mavuto ambiri adawonetsedwa: chizungulire, mseru, kusanza. Patatha mwezi umodzi, kusanza kunatha.

Komabe, ndikuyambitsa kwake, muyenera kusiya kudya mafuta, kuchokera pachakudya choterocho, thanzi lanu limayamba kuipiraipira. Mlingo pang'onopang'ono umachulukirachulukira, monga momwe izi zimachitikira. Kwa miyezi ingapo ndinataya kilogalamu 30, koma nditangosiya jakisoni, ma kilogalamu angapo adabweranso.

Mtengo wa zonse zogulitsa ndi singano zake ndi zazikulu, 10 zikwi za zolembera ziwiri, syringes ya chikwi chimodzi pazingwe zana. Mwa zina, ndinalandira mankhwalawo kwaulere, koma si aliyense amene ali ndi mwayi. Pambuyo pa miyezi isanu ndi umodzi yovutitsidwa yanga, mayeso adawonetsa kuti ndilibe matenda ashuga! Zikuwoneka kuti idayamba motsutsana ndi matenda omwe amayambitsidwa ndi Victoza adathandizira kuthana nawo.

Ingogwiritsani ntchito chida ichi popanda malangizo a dokotala.

Nadezhda (ndemanga zabwino)

Matendawa shuga ndi kuchepetsa kunenepa

Ndili ndi matenda a shuga a 2, ndakhala ndikugwiritsa ntchito Victoza kwa nthawi yoposa chaka tsopano. Shuga anali chiyambire 12, mankhwala atangotsika ndi 7.1 ndikukhala pafupifupi ziwerengerozi, samakwera pamwamba.

Kulemera m'miyezi inayi kunapita 20 kilogalamu, sikumakweranso. Zimamveka zopepuka, chakudya chimakhazikitsidwa, ndizosavuta kumamatira ku chakudya.

Mankhwalawa sanayambitse zovuta zilizonse, panali kukhumudwa pang'ono, koma kunadutsa mwachangu.

Vladimir (ndemanga zabwino)

Ndimalola matenda a shuga

Ndili ndi matenda a shuga a 2, omwe amawoneka mwa ine pambuyo pa 40 chifukwa cha kunenepa kwambiri komanso kunenepa kwambiri. Pakadali pano, ndiyenera kutsatira kadyedwe kokhazikika komanso kuchita masewera olimbitsa thupi kuti ndichepetse kunenepa.

Monga mankhwala othandizira, madokotala adapereka Viktoza, omwe amachepetsa kuchuluka kwa shuga m'magazi, pamimba yopanda kanthu, komanso atatha kudya. Pakadali pano, ndikumangomwa mankhwalawa, ndili pachakudya ndi kuchita maphunziro olimbitsa thupi. Mankhwalawa ndi osavuta chifukwa amatha kuperekedwa kamodzi patsiku popanda kumangirizidwa ndi zakudya.

Victoza ali ndi cholembera chosavuta kwambiri, chosavuta kuyambitsa. Mankhwala sioyipa, amandithandiza.

Olga (ndemanga zabwino)

Ndinayamba kugwiritsa ntchito Viktoza miyezi iwiri yapitayo. Shuga adakhazikika, samadumphadumpha, pakhala kupweteka m'matumba, kuphatikizanso kwatayika kuposa ma kilogalamu 20, zomwe ndi zabwino kwambiri kwa ine. Mu sabata yoyamba kumwa mankhwalawa, ndinamva kunyansidwa - ndinali chizungulire, osachedwa (makamaka m'mawa).

Endocrinologist adasankha Viktoza kuti akanthe m'mimba. Jakisoni yekhayo alibe ululu, ngati mutasankha singano yoyenera.Ndinayamba kumwa Victoza ndi mlingo wochepa wa 0,6 mg, ndiye patatha sabata limodzi adotolo anawonjezera mpaka 1.2 mg.

Mtengo wa mankhwalawa, kuti muuike modekha, umafuna kukhala wabwino kwambiri, koma mikhalidwe yanga ndiyenera kusankha.

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