Thiogamma imapezeka m'mitundu iyi:

mapiritsi okhala ndi: biconvex, oblong, achikasu ocheperako komanso oyera kapena achikasu otumphuka mwamphamvu, pali zoopsa kumbali zonse ziwiri, chigawocho chikuwonetsa pakatikati pa utoto wachikasu (ma PC 10 mu matuza, pamatabwa a 3, 6 kapena 10 matuza)
Njira yothetsera kulowetsedwa: mandimu owoneka oyera, achikasu kapena oyera achikasu (50 ml aliyense m'mabotolo agalasi amdima, pamatoni a 1 kapena 10 mabotolo),
lingalirani yankho la kulowetsedwa: madzi oyera obiriwira achikasu (20 ml m'milili yakuda yagalasi, ma ampoules 5 m'makatoni, mu gulu la makatoni a 1, 2 kapena 4).

Piritsi limodzi lili:

yogwira mankhwala: thioctic (alpha lipoic) acid - 600 mg,
othandizira: microcrystalline cellulose, croscarmellose sodium, simethicone, colloidal silicon dioxide, lactose monohydrate, talc, magnesium stearate, hypromellose,
chipolopolo: talc, macrogol 6000, sodium lauryl sulfate, hypromellose.

Mu 1 ml yankho la kulowetsedwa lili:

yogwira mankhwala: thioctic (alpha-lipoic) acid - 12 mg (pa 1 botolo - 600 mg),
othandizira: macrogol 300, meglumine (wowongolera pH), madzi a jakisoni.

Mu 1 ml yoganizira yankho la kulowetsedwa muli:

yogwira mankhwala: thioctic acid - 30 mg (pa 1 ampoule - 600 mg),
othandizira: macrogol 300, meglumine (wowongolera pH), madzi a jakisoni.

Contraindication

ana ndi achinyamata osakwana zaka 18,
nthawi yapakati
Nthawi yonyamula mkaka
glucose-galactose malabsorption, kuchepa kwa lactase, chibadwa cha galactose tsankho (mapiritsi),
Hypersensitivity kwa zida zazikulu kapena zothandiza za mankhwalawa.

Mapiritsi okhala ndi mbali

Mankhwala Tiogamm mu mawonekedwe a mapiritsi amatengedwa pakamwa, pamimba yopanda kanthu, kutsukidwa ndi madzi pang'ono.

Mlingo woyenera - 1 pc. (600 mg) kamodzi patsiku. Kutalika kwa matendawa kumatengera kutha kwa matendawa ndipo kuyambira 30 mpaka 60 masiku.

M'chaka, njira ya mankhwalawa imatha kubwerezedwa katatu.

Njira yothetsera kulowetsedwa, konzekera kwambiri pokonzekera yankho la kulowetsedwa

Mankhwala Thiogamm mu mawonekedwe a yankho amathandizidwa pang'onopang'ono, pamtunda pafupifupi 1.7 ml / min kwa mphindi 30.

Mlingo wovomerezeka tsiku lililonse ndi 600 mg (1 vial ya kulowetsedwa kapena 1 ampoule yokhazikika ya kukonzekera kulowetsedwa). Mankhwalawa amaperekedwa kamodzi patsiku kwa masabata a 2-4. Pambuyo pake wodwalayo amatha kusamutsidwira pakamwa pa Thiogamm muyezo womwewo (600 mg patsiku).

Mankhwala mu mawonekedwe a njira yothetsera kulowetsedwa ndi okonzeka kugwiritsidwa ntchito. Botolo litatulutsidwa m'bokosilo, nthawi yomweyo limakutidwa ndi kesi yapadera yoteteza kuunika kuti lisalowe mu thioctic acid yomwe imakhudzidwa ndi zotsatira zake. Kulowetsedwa kwa mtsempha kumachitika mwachindunji kuchokera pambale.

Mukamagwiritsa ntchito Thiogamma m'njira yokhazikika, choyambirira chimayenera kukonzekera kulowetsedwa. Pazomwezi, zomwe zili mukulumikizira kumodzi kumatsutsana ndi 50-250 ml ya isotonic sodium chloride solution. Yankho lokonzalo limaphimbidwa nthawi yomweyo ndi mlandu woteteza. Njira yothetsera kulowetsedwa imaperekedwa nthawi yomweyo mukakonzekera. Kutalika kwa yosungirako sikupitilira maola 6.

Malangizo apadera

Odwala omwe ali ndi matenda a shuga, makamaka kumayambiriro kwa mankhwala, shuga wa magazi amayenera kuyang'aniridwa. Ngati ndi kotheka, Mlingo wa mankhwala otseguka m'magazi ndi insulin amasinthidwa.

Zizindikiro za hypoglycemia zikaonekera, mankhwalawa a Thiogamm ayenera kuchotsedwa nthawi yomweyo.

Munthawi ya mankhwalawa, ndikofunikira kupewa zakumwa zoledzeretsa zakumwa zoledzeretsa, popeza kuti mowa umachepetsa mphamvu ya mankhwalawo ndipo umakhala pachiwopsezo cha kukula ndi kupitilira kwa neuropathy.

Piritsi limodzi la 600 mg limakhala ndi kuchepera kwa 0,0041 XE (magawo a mkate).

Kugwiritsa ntchito mwachindunji kwa Thiogamma sikukhudza kudwala kwa wodwala kuyendetsa magalimoto ndikugwira ntchito ndi njira zina zowopsa. Koma ndikofunikira kuganizira zovuta zotere kuchokera ku endocrine system, chifukwa kuchepa kwa shuga wamagazi, monga kusokonezeka kowoneka ndi chizungulire.

Kupanga ndi mawonekedwe a kumasulidwa

Zomwe zimapangidwa koyambirira zimapangidwa ku Germany ndipo zili ndi mitundu ingapo: lingalirani za yankho, mapiritsi ndi yankho la kukoka kwamkati. Chomwe chimagwiritsa ntchito mankhwalawa ndi thioctic kapena lipoic acid.

Zothandiza pazinthu piritsi ndi:

cellcrystalline mapadi,
lactose monohydrate,
talcum ufa
magnesium wakuba,
silicon dioxide.

Mapiritsiwo ali ndi mawonekedwe obic biconvex. Zadzaza matuza a zidutswa 10. Phukusi lililonse la makatoni limatha kukhala ndi matuza atatu mpaka 10. Mtengo wa mapiritsi a Tiogamma umayambira ku ruble 800 ndipo umatha kufika pa ma ruble a 1000-1200.

Gogomezera pokonzekera yankho lilinso ndi acidic wa asidi. Zinthu zothandiza ndi madzi a jakisoni, macrogol, meglumine.

Kuphatikiza kumayikika mu 20 ml galasi ma ampoules, omwe amaikidwa mu maselo apulasitiki a 5 zidutswa. Phukusi la makatoni pamatha kukhala ma mbale 1, 2 kapena 3 okhala ndi maselo. Ampoules amapangidwa ndi galasi lakuda, lomwe limathandiza kuteteza yankho ku zowonongeka za dzuwa. Mtengo wa Tiogamma ampoules umachokera ku rubles 190−220 pachinthu chimodzi.

Njira Zothetsera mu kapangidwe kake kamakhala ndi zothandizira zomwezo monga momwe zimakhalira. Atakulungidwa m'mabotolo amdima amdima. Kuchuluka kwa 50 ml iliyonse. Mtengo uli mgulu la ma ruble 200−250 pa botolo limodzi.

Mankhwala

Zomwe zimagwiritsa ntchito mankhwalawa ndi thioctic (alpha-lipoic) acid. Ndi ma antioxidant amkati omwe amamangirira zopitilira muyeso. Thioctic acid imapangidwa m'thupi nthawi ya oxidative decarboxylation ya alpha-keto acid. Ndi coenzyme ya maenzenzime ambiri mu mitochondria ndipo amaphatikizidwa ndi oxidative decarboxylation ya alpha-keto acid ndi pyruvic acid.

Alpha-lipoic acid imathandizira kuchepetsa shuga m'magazi, kuonjezera kuchuluka kwa glycogen m'chiwindi ndikugonjetsa insulin kukana. Mwa makina ochitira, ili pafupi ndi mavitamini a gulu B.

Thioctic acid amawongolera chakudya komanso lipid metabolism, imakhudza ntchito ya chiwindi komanso imathandizira kagayidwe ka cholesterol. Ili ndi hypolipidemic, hypoglycemic, hepatoprotective ndi hypocholesterolemic kwenikweni. Chimalimbikitsa thanzi la neurons.

Mukamagwiritsa ntchito meglumine mchere wa alpha-lipoic acid (osatenga nawo mbali) pazomwe mungagwiritsire ntchito makonzedwe amkati, zovuta zoyipa zimatha kuchepetsedwa.

Pharmacokinetics

Pakaperekedwa pakamwa, thioctic acid imatengedwa mwachangu komanso kwathunthu kuchokera m'mimba. Ndi zakudya zomwezi munthawi yomweyo, kuyamwa kwa mankhwalawo kumachepetsedwa. Bioavailability ndi 30%. Kuti mukwaniritse kuchuluka kwa zinthu zomwe zimagwira, zimatenga mphindi 40 mpaka 60.

Thioctic acid imadutsa mphamvu yoyamba kudzera pachiwindi. Zimapukusidwa m'njira ziwiri: ndi conjugation komanso oxidation wam'mbali.

Kuchuluka kwa magawidwe ndi pafupifupi 450 ml / kg. Mpaka 80-90% ya mlingo womwe umatengedwa ndi impso mu mawonekedwe a metabolites ndipo osasinthika. Kutha kwa theka-moyo kumapanga kuchokera 20 mpaka 50 mphindi. Chilolezo chokwanira cha plasma cha mankhwalawa ndi 10-15 ml / min.

Nthawi yofika ndende yozama ya plasma ndi mtsempha wa mtsempha wa Thiogamm ndi mphindi 10-11, ndipo kuchuluka kwa plasma ndende ndi 25- 38 μg / ml. AUC (dera lozungulira nthawi yokhotakhota) pafupifupi 5 μg / h / ml.

Njira yothetsera kulowetsedwa ndikuyang'anitsitsa pakukonzekera njira yothetsera kulowetsedwa

Njira yothetsera vutoli, kuphatikizapo yokonzedwera kuchokera kumagawo, imayendetsedwa kudzera m'mitsetse.

Mlingo wa tsiku ndi tsiku wa Thiogamma ndi 600 mg (1 botolo la yankho kapena 1 ampoule of concentrate).

Mankhwalawa amatumizidwa kwa mphindi 30 (pamlingo pafupifupi 1.7 ml pa mphindi).

Kukonzekera kwa yankho kuchokera mwakuya: zomwe zili 1 ampoule zimasakanizidwa ndi 50-250 ml ya 0,9% sodium kolorayidi. Mukamaliza kukonzekera, yankho lake liyenera kuyimbidwa nthawi yomweyo ndi nkhani yopanda magetsi. Sungani maola opitilira 6.

Mukamagwiritsa ntchito njira yomwe inakonzedwa kale, ndikofunikira kuchotsa botolo kuchokera pazonyamula ma katoni ndikuwaphimba mwachangu ndi mlandu woteteza. Kulowetsedwa kuchitike mwachindunji vial.

Kutalika kwa chithandizo ndi masabata 2-2. Ngati ndi kotheka, pitilizani mankhwala, wodwalayo amamuika piritsi la mankhwalawo.

Kagayidwe kachakudya mankhwala Thiogamma: zomwe zotchulidwa, zikuchokera ndi mtengo wa mankhwalawa

Pali mankhwala ambiri a metabolic omwe akhudzidwa ndi mafuta ndi ma carbohydrate metabolism. M'modzi mwa iwo ndi Tiogamma.

Mankhwalawa akukhudzidwa ndimayendedwe a metabolic omwe amapezeka m'chiwindi, amathandizira kutsitsa cholesterol, kuwonjezera kuchuluka kwa glycogen m'chiwindi, amathandizira kukana kwa maselo kupita ku insulin ndipo potero amathandizira kuchepetsa shuga m'magazi, omwe ndi ofunika kwambiri kwa odwala matenda ashuga (makamaka mtundu wachiwiri), ndipo yatchulanso katundu wa antioxidant.

Ndikosavuta kwa munthu kugona kuti amvetsetse kuti Tiogamm ndi kuti ndi kuti? Chifukwa cha kupadera kwachilengedwe kwa thupi, mankhwalawa amadziwonetsa ngati hepatoprotective, hypoglycemic, hypolipidemic ndi hypocholesterolemic mankhwala, komanso mankhwala omwe amapangitsa kuti neurotrophic neurons ipangidwe.

Zotsatira za pharmacological

Thiogamma ndi wa metabolic group la mankhwala, mankhwala omwe amagwira ntchito momwemo ndi thioctic acid, omwe nthawi zambiri amaphatikizidwa ndi thupi pa oxidative decarboxylation ya alpha-ketone acid, ndi endo native antioxidant, amagwira ntchito ngati coenzyme ya mitochondrial multenzyme complexes ndipo amagwira ntchito mwachindunji pakapangidwe kazinthu zazikulu zama cell.

Thioctic acid imakhudzanso kuchuluka kwa glucose, imathandizira kuyika kwa glycogen m'chiwindi, komanso kutsitsa insulin kukana pa ma cellular. Ngati kaphatikizidwe ka alpha-lipoic acid mthupi kamakhala koipa chifukwa cha kuledzera kapena kuchuluka kwa zinthu zomwe zimapangitsa kuti mankhwala asawonongeke (mwachitsanzo, matupi a ketone) komanso kuphatikizira kwambiri ma radicals aulere, kusapeza bwino mu dongosolo la aerobic glycolysis.

Thioctic acid imapezeka m'thupi m'njira ziwiri ndipo imagwira ntchito mopatsirana komanso kuchepetsa, kuwonetsa zotsatira za antitoxic ndi antioxidant.

Thiogamm mu njira ndi mapiritsi

Amachita nawo kayendedwe ka mafuta ndi kagayidwe kazakudya. Chifukwa cha hepatoprotective, antioxidant ndi antitoxic zotsatira, zimasintha ndikuyambiranso ntchito ya chiwindi.

Thioctic acid munthawi yama pharmacological thupi lake imakhala yofanana ndi mavitamini a B .. Amasintha neurotrophic neurons komanso imathandizira kusinthika kwa minofu.

Pharmacokinetics ya Thiogamm ndi motere:

Ndi pakamwa makonzedwe, thioctic acid pafupifupi kwathunthu ndipo mwachangu odziwitsidwa mu gawo la m'mimba. Imafufutidwa mu mawonekedwe a metabolites kudzera mu impso za 80-90% ya zinthu, metabolites zimapangidwa ndi makulidwe a oxidation am'mbali ndi conjugation, metabolism imayikidwa pazomwe zimatchedwa "gawo loyambirira" kudzera pachiwindi. Kuzindikira kwakukulu kumafika pamphindi 30 mpaka 40. Bioavailability ukufika 30%. Hafu ya moyo ndi mphindi 20-50, chilolezo cha plasma ndi 10-15 ml / min,
mukamagwiritsa ntchito mankhwala a thioctic acid m'mitsempha, ndende yozunguliridwa imadziwika pambuyo pa mphindi 10-15 ndipo ndi 25-38 μg / ml, malo omwe amaponderezedwa amakhala pafupifupi 5 μg h / ml.

Zogwira ntchito

The yogwira pophika mankhwala a Tiogamma ndi thioctic acid, omwe ali m'gulu la amkati metabolites.

Panjira yothetsera jakisoni, chinthu chogwira ntchito ndi alpha lipoic acid mu mawonekedwe a mchere wa meglumine.

Zomwe zimapezeka piritsi la piritsi ndi microcellulose, lactose, talc, colloidal silicon dioxide, hypromellose, sodium carboxyl methyl cellulose, magnesium stearate, macrogol 600, semethicone, sodium lauryl sulfate.

Paziphatikizo za jakisoni, meglumine, macrogol 600 ndi madzi a jakisoni amachita ngati zowonjezera.

Tiogamm: amatanthauza chiyani?

Thiogamma ali m'gulu la okonza metabolic amkati, amatenga gawo la chakudya ndi mafuta pamaselo a ma cell, amathandizira kutsitsa magazi, amalimbikitsa kuchulukana kwa glycogen mu chiwindi, amachepetsa kukana kwa insulin, ali ndi antioxidant komanso antitoxic zotsatira, ali ndi hepatoprotective, hypolipidemic ndi hypocholesteric zotsatira. .

Chifukwa cha mawonekedwe ake, zotsatira zake pakulimbitsa thupi, njira ya Thiogamm imalembedwa ngati mankhwala a prophylactic achire ndi:

matenda ashuga polyneuropathy,
bongo
hepatitis osiyanasiyana etiologies, matenda enaake, chiwindi chamafuta,
poizoni ndi poyizoni, komanso mchere wamafuta ambiri.
ndi mitundu yosiyanasiyana ya kuledzera.

Thiogamm ali ndi zotsutsana zingapo, monga hypersensitivity alpha-lipoic acid, kusowa kwa lactase, galactose tsankho.

Sizingatengedwe ngati ali ndi vuto la malabsorption, kutanthauza kuti matendawa amatha kuyamwa ndi matumbo, m'matumbo am'mimba komanso kupuma, kulephera kwamkati, kufooka kwa mtima, kusayenda bwino kwa magazi m'thupi, kulephera kwa impso, kuchepa thupi, uchidakwa, komanso matenda ena aliwonse. ndi mikhalidwe yomwe imatsogolera lactic acidosis.

Mukamagwiritsa ntchito Thiogamma, nseru, chizungulire, kusanza, kutsegula m'mimba, kupweteka kwam'mimba, thukuta kwambiri, matupi awo sagwirizana ndi khungu lanu, hypoglycemia imatheka, chifukwa kugwiritsa ntchito shuga kumathandizira.

Matendawa amapezeka kwambiri kawirikawiri komanso kupanikizika kwa anaphylactic.

Mukamagwiritsa ntchito Tiogamma, anthu odwala matenda ashuga amafunika kuwonetsetsa kuti shuga ali ndi mphamvu zambiri, chifukwa thioctic acid imafulumira nthawi yogwiritsira ntchito shuga, yomwe, ngati mulingo wake umagwa kwambiri, zimatha kudzetsa vuto la hypoglycemic.

Ndi kuchepa msanga kwa shuga, makamaka poyambira kumwa Thiogamma, nthawi zina kuchepetsa kumwa kwa insulin kapena mankhwala a hypoglycemic kumafunika. Kugwiritsa ntchito mankhwala osokoneza bongo omwe ali ndi mowa ndizoletsedwa panthawi yogwiritsira ntchito Tiogamma, chifukwa chithandizo chochepetsedwa chimachepa, ndipo mawonekedwe oopsa a neuropathy omwe amapita patsogolo amatha kuchitika.

Alpha-lipoic acid sigwirizana ndi kukonzekera komwe kumakhala ndi dextrose, Ringer-Locke solution, cisplatin ikagwiritsidwa ntchito palimodzi. Amachepetsa magwiridwe antchito omwe amakhala ndi chitsulo ndi zitsulo zina.

Thiogamm amapangidwa ku Germany, mtengo wamba ndi:

poika mapiritsi a 600 mg (mapiritsi 60 pa paketi iliyonse) - 1535 ma ruble,
poika mapiritsi a 600 mg (zidutswa 30 pa paketi) - ma ruble 750,
njira yothetsera kulowetsedwa kwa 12 ml / ml mu Mbale 50 ml (zidutswa 10) - ma ruble 1656,
njira yothetsera kulowetsedwa 12 ml / ml botolo la 50 ml - 200 ma ruble.

Makanema okhudzana nawo

Pa kugwiritsa ntchito alpha lipoic wa matenda ashuga mu kanema:

Kufotokozera kumeneku kwa mankhwalawo a Thiogamma ndi zinthu zophunzirira ndipo sangagwiritsidwe ntchito ngati malangizo. Chifukwa chake, musanagule ndikugwiritsa ntchito nokha, muyenera kufunsa dokotala yemwe adzasankhe njira yothandizirana ndi mankhwalawa.

Imakhazikika pamisempha ya shuga kwa nthawi yayitali
Imabwezeretsa kapangidwe ka insulin

Phunzirani zambiri. Osati mankhwala. ->

Kuyanjana kwa mankhwala osokoneza bongo

Kugwiritsira ntchito pamodzi kwa thioctic acid ndi glucocorticosteroids kumawonjezera mphamvu yawo yotsutsana ndi kutupa, ndi chisplatin - kumachepetsa mphamvu ya cisplatin, wokhala ndi insulin kapena othandizira pakamwa - ndikotheka kuwonjezera mphamvu zawo, ndi ethanol ndi metabolites yake - mphamvu ya thioctic acid imachepa.

Thiogamma amamanga zitsulo, kotero mankhwalawa sayenera kugwiritsidwa ntchito limodzi ndi mankhwala okhala ndi zitsulo (mwachitsanzo, magnesium, iron, calcium). Pakati pa kumwa thioctic acid ndi mankhwalawa ayenera kukhala osachepera maola 2.

Yankho la kulowetsedwa sikuyenera kusakanikirana ndi yankho la Ringer, yankho la dextrose ndi mayankho omwe amakhudzana ndi magulu a SH-magulu osagwirizana.

Mankhwala

Lipoic kapena thioctic acid m'thupi la munthu wathanzi amapangidwa mokwanira ndipo amakhudzidwa pafupifupi ndi zochita zonse za metabolic. Zotsatira za kuphwanya kulikonse, kupanga kwake kumachepa kwambiri, komwe kumayambitsa ma pathologies osiyanasiyana.

Chifukwa cha kutuluka kwa chinthu ichi kuchokera kunja, njira za metabolic zimasinthidwa. Maselo amatetezedwa ku zotsatira zoyipa ndikupitilizabe kugwira ntchito nthawi zonse.

Kuchita izi kumakupatsani mphamvu kagayidwe kazakudya komanso kupewa matenda a shuga. Kuphatikiza apo, lipoic acid imakhudzana ndi kusinthana kwa cholesterol ndikuletsa kuyikika kwa cholesterol plaques pamakoma amitsempha yamagazi.

Komabe, chipangizochi sichimangotenga nawo gawo la lipid metabolism, komanso zimathandizira kuchotsa zochuluka kuchokera mumagazi, zomwe ndizopindulitsa kwambiri pakuyenda kwa magazi.

Katundu wina wa mankhwalawa ndi kuthekera kuchotsa poizoni ndi zinthu zowola za ziphe kapena zama mankhwala. Izi ndizotheka chifukwa cha chiwindi ndi ntchito yake. Kuphatikiza apo, thioctic acid yatulutsa katundu wa hepatoprotective ndipo imathandizira kwambiri kugwira ntchito kwa chiwalo.

Pogwiritsa ntchito njira ya Tiogamm panjira, kupatsa mphamvu kwamitsempha yama mitsempha ndi mitsempha ya magazi kumakhala bwino, komwe kumakhala kupewa zilonda zam'mimba, neuropathy, angiopathy ndi zovuta zina zamitsempha ndi mtima. Naturalization ya psychoemotional bwino, kugona, chidwi ndi kukumbukira zimawonedwa.

Zotsatira zabwino za mankhwala pakhungu zidadziwika. Imathandizanso kukwiya, imathandizira kupanga collagen, imachepetsa kuchuluka kwa makwinya, imachotsa kukhuthala, kuuma, kubwerera ndikusintha ndi mtundu wathanzi.

Mukamagwiritsa ntchito mtundu uliwonse wa mankhwalawa, kuyamwa kwathunthu ndi kukonza kwa kachipangizoka kumachitika. Metabolism imachitika m'chiwindi ndipo pa mlingo woyamba, kupezeka kwa zinthu ndi 30% yokha. Pakuvomerezedwa mobwerezabwereza komanso maphunzirowa, pang'onopang'ono chiwerengerochi chimakwera ndikuchulukanso 60%.

Mafuta amapezeka m'matumbo ang'onoang'ono. Kuchuluka kwazomwe zimagwira m'magazi sikuwonekanso pakadutsa mphindi 30 mwa munthu wathanzi. Odwala omwe ali ndi vuto lililonse logaya chakudya, nthawi imeneyi imachulukitsa katatu.

Kuwonongeka kwa zinthu zowola zamankhwala kumachitika kudzera mu impso ndipo kumayambira patatha maola awiri ndi atatu. Pafupifupi zida zonse zimapakidwa m'malo osinthika ndipo ndi 2−5% yokha yomwe imasinthidwa. Odwala omwe ali ndi matenda aakulu a impso, nthawi yochotsa imawonjezeka ndi maola 3-5.

Mitundu yogwiritsira ntchito mankhwalawo ndiyotakata kwathunthu. Nthawi zambiri, mankhwalawa amagwiritsidwa ntchito m'njira zosiyanasiyana:

Poizoni wa thupi ndi chakudya, mwachitsanzo, bowa, komanso poizoni.
Mowa polyneuropathies a mawonekedwe osakhazikika, kuwonongeka kwa maselo aubongo ndi zinthu zowola za ethyl mowa.
Angiopathy kapena neuropathy pamaso pa matenda a shuga a mtundu uliwonse.
Mafuta hepatosis.
Cirrhosis yayikulu ndi zovuta zina ziwalo.
Hepatitis yamitundu yosiyanasiyana.
Kuletsa endarteritis yotsogola.
Kuphwanya lipid kagayidwe kake ndi kusintha kwa kusintha kwa ma atherosselotic m'mitsempha yamagazi.

Ndikofunikira kwambiri kupita ku chithandizo cha odwala omwe, chifukwa cha matenda osokoneza bongo kapena uchidakwa wambiri, amavutika ndikuphwanya zam'munsi zam'munsi.

Zotsatira zoyipa

Kulephera kutsatira malangizo kapena malamulo oyanjana ndi mankhwalawa ndi mankhwala ena kumapangitsa kuti pakhale zovuta zambiri.

Nthawi zambiri wodwala amakhala mutu, chizungulire komanso kuwonongeka konsekonse, kumeza tiziwalo tating'onoting'ono ndi thukuta, minyewa yam'mbali yam'munsi.

Nthawi zambiri zachulukitsa matendaMwachitsanzo, thrombophlebitis. Chimbudzi chimasokonekera, chimawonedwa kusanza, kusanza mseru, kudzimbidwa kapena kupumira kosalekeza, kuphwanya masamba.

Nthawi zina, wodwalayo amakhala ndi nkhawa Maso osokonezeka ndi kuchepa kwakukulu kwa mtundu wamasomphenya nthawi iliyonse masana, nkhawa zopanda pake, chisokonezo cha kugona, kukumbukira, kuyika chidwi, chidwi cha kutaya kwamva.

Milandu yamankhwala osokoneza bongo, omwe amawonekera kwambiri kukulira ambiri mkhalidwe ndi kuchuluka kwa mavuto. Kuphatikiza apo, pali zolanda khunyu, kuyerekezera zinthu m'magazi, kusanza kosalephera, kuzindikira, kugwedezeka miyendo.

Vuto lalikulu kwambiri likhala hypoglycemic chikomokere ndipo pachimake mtima kuperewera. Zinthu ngati izi zimasokoneza thanzi la wodwalayo ndipo zimafunikira chisamaliro chamankhwala oyenerera.

Izi zitha kuchitika pomamwa madzi oyera ambiri kenako ndikutsuka. Izi zithandiza kuchepetsa pang'ono mkhalidwe wa wodwalayo komanso kupewa kutulutsa zinthu zina m'magazi.

Malangizo ogwiritsira ntchito

Fomu yamapiritsi Amagwiritsidwa ntchito ngati chithandizo chofunikira komanso chothandiza. Monga lamulo, njira ya achire imatenga milungu inayi mpaka isanu ndi itatu, kutengera kuuma kwa matendawa komanso mavuto ena okhudzana ndi ziwalo zamkati.

Tengani piritsi 1 ndikulimbikitsidwa patsiku. Ndiwosokonekera kuti akupera piritsi m'njira iliyonse musanatenge. Iyenera kutsukidwa ndi madzi ambiri.

Kuchulukitsa mulingo womwewo osavomerezeka. Dziwani kuti mukamamwa mankhwalawo ndi chakudya, mayamwidwe ake amayamba kuchepetsedwa. Komabe, izi sizikhudza kuchiritsa komaliza.

Gogomezera osagwiritsidwa ntchito mwa mawonekedwe ake oyera. Amadzipaka m'mabotolo ndi saline 0,9%. Kuchuluka kwa botolo ndi 200 ml. Ngati pazifukwa zilizonse wodwala salimbikitsidwa kuperekera madzi ambiri mumitsempha, kuchuluka kwa njira ya mchere kumaloledwa kutsitsidwa mpaka 50 ml.

Kutalika kwa njira ya achire ndi kuyambira masiku 10 mpaka 20 ndipo zimatengera kuopsa kwa matenda omwe akudwala. Ndondomeko zimachitidwa mchipatala chokha. Mankhwalawa amaperekedwa kudzera pa dontho kwa mphindi 30 mpaka 40.

Ndizoyenera kuyang'anira kuti botolo lomwe lili ndi vutoli ndilofunika kutsekedwa ndi chikwama chapadera, cha opaque, chomwe chimamangirizidwa phukusi lililonse.

Mabotolo a Zothetsera 50 ml amagwiritsidwanso ntchito ngati mtsempha wa mtsempha wamagetsi molingana ndi chiwembu chofanana ndi cholimbira. Chimodzi mwa mawonekedwe awa ndi kupezeka kwa phukusi lakuda payokha pa botolo lililonse.

Ngati yankho lokonzekera lidatsegulidwa, koma palibe njira yowayambitsa, amaloledwa kusunga mankhwalawa osaposa maola 6. Pambuyo pake, salinso yoyenera kugwiritsidwa ntchito ndipo ndiyenera kutayidwa. Muyenera kuwunika mosamala tsiku lomaliza la fomu iliyonse. Ndalama zomwe zatulutsidwa zimatha kubweretsa zovuta zazikulu.

Nthawi zambiri, yankho lokonzedwa lopangidwa m'mabotolo 50 ml limagwiritsidwa ntchito ngati mankhwala osamalira khungu. Imagwiritsidwa ntchito m'njira yoyenera tsiku lililonse mpaka vutoli litazimiririka.

Pogwiritsa ntchito pafupipafupi, ziphuphu zakumaso, makina abwino, ziphuphu zakumaso ndi zolakwika zina zamkhungu zimazimiririka. Kugwiritsira ntchito kotere sikumadziwika ndi mankhwala ovomerezeka, koma amagwiritsidwa ntchito mwachangu ndi mafani a njira zina.

Mtengo wa mankhwala othandizira ndiwokwera kwambiri, kotero ambiri amayesa kupeza njira ina yofananirana ndi mawonekedwe ndi katundu wofanana.

Otsatirawa amatchulidwa ngati ma fanizo odziwika kwambiri:

Mankhwala Mgwirizano zopangidwa ndi kampani yopanga mankhwala ku Germany. Wopezeka mu mawonekedwe a piritsi, kapisozi ndi kuganizira kwambiri. Gawo logwira ntchito ndilofanana ndi chida choyambirira, koma lili ndi mitundu yosiyanasiyana. Ndi kulowetsedwa kwa mtsempha, botolo lomwe lili ndi yankho liyenera kutseka ndi thumba lakuda. Chida ichi chimagwiritsidwa ntchito ngati gawo limodzi la zovuta za matenda a shuga ndi matenda osiyanasiyana a mtima. Siligwiritsidwa ntchito pa mkaka wa m'mawere, kubereka khanda, ubwana komanso kusalolera kwa mankhwala. Njira yothandizira achire imakhala ndi 10-20 otsikira, njirazi zimachitika kuchipatala tsiku lililonse.
Njira Oktolipen ilinso ndi mitundu ingapo ya mapiritsi: mapiritsi, makapisozi ndi kuyang'ana mozama kuti mupeze yankho. Ili ndi katundu wotchedwa hepatoprotective ndi hypoglycemic. Chifukwa cha izi, imagwiritsidwa ntchito mosamala mu zovuta za matenda a shuga mellitus a mtundu woyamba ndi wachiwiri. Mankhwala contraindicated odwala kwambiri aimpso kulephera, tsankho kwa yogwira chigawo, pa mimba ndi mkaka wa m`mawere. Maphunzirowa nthawi zambiri amatha masiku 7 mpaka 21, kutengera kuopsa kwa vuto la wodwalayo.
Thioctacid imaperekanso kuchiritsa chifukwa cha zoleic acid. Amapezeka mu mawonekedwe a yankho mu 24 ml ampoules ndi mapiritsi. Zimatengera mankhwala okhala ndi zochepa zotsutsana. Osamapereka mankhwala kwa odwala omwe ali ndi chifuwa kapena chizolowezi chofananira, nthawi yapakati kapena yoyamwitsa. Machitidwe a mankhwalawa ndi ofanana ndi a Tiogamm. Amakulolani kuti muchotse mwachangu chizindikiro cha polyneuropathy, angiopathy ndi zovuta zina zoyambitsa matenda a shuga 1.
Mankhwala Dialipon opangidwa ndi kampani yopanga mankhwala ku Ukraine. Kuphatikizikako kumakhala ndi mankhwala a lipoic acid osiyanasiyana. Mankhwalawa amapezeka mu mawonekedwe a makapisozi, yankho lokonzekera lopangidwa m'mabotolo 50 ml. Palinso yokhazikika mu ampoules. Mankhwalawa ali ndi phindu pa boma la chiwindi komanso amachepetsa kuchuluka kwa shuga m'magazi, amathandizira kuchepetsa zomwe odwala omwe ali ndi matenda osokoneza bongo omwe ali ndi zovuta zingapo. Zogwiritsidwa ntchito chimodzimodzi ndi zida zakale.

Malangizo ndi kukhazikika

Thiogamm nthawi zambiri limalekeredwa. Nthawi zambiri, kuphatikiza pazofanana, zotsatira zotsatirazi zimachitika:

kuchokera ku endocrine system: kuchepa kwa kuchuluka kwa shuga m'magazi (kusokonezeka kowoneka, thukuta kwambiri, chizungulire, kupweteka kwa mutu),
mbali yamanjenje yamkati: kuphwanya kapena kusintha kukoma, kupweteka, khunyu,
Kuchokera kwa hemopoietic dongosolo: hemorrhagic zidzolo (purpura), thrombocytopenia, thrombophlebitis, kuloza zotupa pakhungu ndi mucous nembanemba,
pakhungu ndi minyewa yolimba: chikanga, kuyabwa, zotupa,
mbali ya gawo la masomphenyawo: diplopia,
thupi lawo siligwirizana: urticaria, zokhudza zonse zimachitika (kusapeza bwino, nseru, kuyabwa) mpaka chitukuko cha anaphylactic mantha,
zimachitika mdera: Hyperemia, mkwiyo, kutupa,
ena: ngati mankhwala akupangidwira msanga - kupuma movutikira, kuchuluka kwa nkhawa (pamakhala kumva kuwawa m'mutu).

Bongo

Ndi mankhwala osokoneza bongo a thioctic acid, zizindikiro zotsatirazi zimachitika: mutu, nseru, ndi kusanza. Mukumwa 1040 g wa Thiogamma osakanikirana ndi mowa, milandu yovuta kwambiri idadziwika, mpaka zotsatira zakupha.

Mu pachimake mankhwala osokoneza bongo, kusokonezeka kapena psychomotor mukuchitika, nthawi zambiri limodzi ndi lactic acidosis ndi kudandaula kosagwirizana. Milandu ya hemolysis, rhabdomyolysis, hypoglycemia, kufooka kwa mafupa, omwenso amapezeka mkati mwa kuvulala kwamitsempha, kufooka kwamitundu yambiri komanso kugwedezeka.

Mankhwalawa ndi chizindikiro. Palibe mankhwala enieni a thioctic acid.

Ndemanga za Tiogamma

Mankhwalawa nthawi zambiri amapatsidwa odwala omwe ali ndi matenda osokoneza bongo komanso chiyembekezo cha polyneuropathies, chifukwa iyi ndi njira yabwino yothandizira matenda amanjenje.

M'mawunikidwe a Tiogamma, zimadziwika kuti ndi chithandizo chochepa kwambiri, zovuta zoyambitsa matenda a endocrine zitha kupewedwa. Kuphatikiza mukugwiritsa ntchito mankhwalawa ndikutheka kochepa kwambiri kwa zotsatira zoyipa.

Akatswiri amathandizanso pa Tiogamma, pozindikira momwe amathandizira, zomwe zimapangitsa kuti pakhale zovuta komanso zovuta zochepa za bongo.

Thupi lawo siligwirizana zomwe zingachitike munthawi ya chithandizo nthawi zambiri zimawonedwa mwa odwala omwe ali ndi vuto lotsogolera. Kuti mupewe izi, tikulimbikitsidwa kuti muziyeserera thupi lanu musanagwiritse ntchito mankhwala.

Mtengo wa Thiogammu pamafesi

Mitengo ya Thiogamm m'misika:

mapiritsi okhala ndi filimu, 600 mg (ma 30 ma PC. pa paketi iliyonse) - kuchokera ma ruble 894,
mapiritsi okhala ndi filimu, 600 mg (ma 60 ma PC. pakiti iliyonse) - kuchokera ku ma ruble a 1835,
yankho la kulowetsedwa (botolo la 50 ml, 1 pc.) - kuchokera ma ruble 211,
yankho la kulowetsedwa (botolo la 50 ml, ma PC 10) - kuchokera 1784 ma ruble.
lingalira kwambiri pakukonzekera njira yothetsera kulowetsedwa (ma ampoules 20 ml, ma PC 10) - kuchokera ku 1800 rubles.

Ndemanga pazotsatira za mankhwalawa

Nikolay. Ndakhala ndikuvutika ndi shuga wambiri kwa zaka zoposa 10. M'zaka zochepa zapitazi, mkhalidwe wanga wakuipa kwambiri, makamaka miyendo ndi kusokonezeka kwa chidwi mwa iwo. Dokotala adapereka yankho la 50 ml ngati mayeso. Sindinali wotsimikiza za chidacho ndipo ndinapita pagawo limodzi. Maganizo a odwala ambiri ndiabwino, ndidaganiza zoyesa. Pambuyo pa chithandizo chamankhwala 10, ndinamva kusintha. Ndine wokhutira ndi momwe mankhwalawo amathandizira.

Michael. Kwa zaka zingapo tsopano, miyezi isanu ndi umodzi iliyonse ndakhala ndikumwa mapiritsi awa, chifukwa ndimadwala polyneuropathy. Ankakhala wotopa msanga, ndipo ululuwo sunapumulitse. Zochitika masiku 20 mpaka 30 zimandithandiza kumva bwino. Ndinayesa kufanana kwa malonda, koma zoyambirira zimakhala ndi zotsatira zabwino.

Tamara Matenda a shuga a Type I adapezeka osati kale kwambiri, zaka zosakwana 3 zapitazo. Chaka chokha chatha ndidayamba kumva kutopa kwamiyendo yanga, makamaka usiku. Matenda anga adandiwopsa, ndidatembenukira kwa dotolo, yemwe adandiyatsira mapiritsi a Tiogamm. Ndidatenga milungu itatu molingana ndi malangizo, ndipo zotsatira zake zidandisangalatsa. Ndipitiliza chithandizo.

Pali zotsutsana.Ndikofunikira kufunsa katswiri.

Zizindikiro zogwiritsidwa ntchito

Thiogamm imakhala ndi mawonekedwe ogwiritsira ntchito, chifukwa cha zomwe zimagwiritsidwa ntchito ndi mankhwala. Zifukwa zazikulu zosankhira ndalama:

matenda a shuga
zovuta za chiwindi: mafuta osokoneza bongo a hepatocytes, cirrhosis ndi hepatitis a magawo osiyanasiyana,
kuwonongeka kwa mowa kwa misempha ya mitsempha
poyizoni wokhala ndi zizindikiro zowopsa (bowa, mchere wazitsulo zolemera),
mphamvu zamagetsi kapena zotumphukira polyneuropathy.

Mlingo ndi makonzedwe

Kutengera mtundu wa mankhwalawa, momwe angagwiritsidwire ntchito ndi kumwa mosiyanasiyana. Ndikofunikira kwambiri kutsatira malamulo akamagwiritsa ntchito yankho ndikuwunikira pakukonzekera yankho. Mukachotsa botolo m'bokosilo, liwuleni ndi pepala loteteza kuwala (kuunika kumawononga thioctic acid). Njira yothetsera imakonzedwa kuchokera ku zomwe zimakhudzidwa: zomwe zimaphatikizidwa kumodzi zimaphatikizidwa ndi 50-250 ml ya 0,9% sodium chloride solution. Ndikulimbikitsidwa kuperekera mankhwalawo nthawi yomweyo, nthawi yayitali yosungirako ndi maola 6.

Mapiritsi a Thiogamm

Mapiritsi amatengedwa kamodzi patsiku musanadye ndi Mlingo womwe adafotokozeredwa ndi adotolo, mapiritsiwo samatsalidwa ndikusambitsidwa ndi madzi pang'ono. Kutalika kwa maphunzirowa ndi masiku 30-60 ndipo zimatengera kuopsa kwa matendawa. Kubwereza zamankhwala ndizovomerezeka kuchita kawiri kapena katatu pachaka.

Thiogma kwa otsitsira

Mukamagwiritsa ntchito mankhwalawa, ndikofunika kukumbukira kugwiritsa ntchito vuto loteteza mopepuka mutachotsa botolo m'bokosi. Kulowetsedwa kuyenera kuchitidwa, kuwona jekeseni wa 1.7 ml pa mphindi. Ndi mtsempha wamkati, amafunika kuti azitha kuyenda pang'onopang'ono (mphindi 30), mlingo wa 600 mg patsiku. Njira ya mankhwala ndi milungu iwiri kapena inayi, pambuyo pake amaloledwa kutalika kwa mankhwalawa pakamwa pakamwa piritsi limodzi la 600 mg.

Kwa khungu

Mankhwala Tiogamm wapeza momwe angagwiritsire ntchito mankhwala amaso. Pachifukwa ichi, zomwe zili m'mabotolo ogwiritsa ntchito zimagwiritsidwa ntchito. Kugwiritsa ntchito fomu iyi kumachitika chifukwa cha kuchuluka kwa mankhwalawa. Mankhwala mu ampoules si koyenera chifukwa kuchuluka kachulukidwe ka zomwe zimapangitsa, izi zitha kuyambitsa mavuto. Njira yothetsera vutoli iyenera kugwiritsidwa ntchito kawiri pa tsiku - m'mawa ndi madzulo. Musanagwiritse ntchito, muyenera kusamba nkhope yanu ndi madzi ofunda (mwina ndi mafuta odzola) kuti muchepetse ma pores ndikulowerera kwambiri kwa mankhwala othandizira.

Pa nthawi yoyembekezera

Chifukwa cha zomwe zili pazinthu zomwe zikugwira, kugwiritsidwa ntchito kwa Thiogamma panthawi yoyembekezera komanso mkaka wa m'mawere ndizoletsedwa. Izi zimalumikizidwa ndi chiwopsezo chachikulu cha kugwira ntchito kwa mwana wosabadwayo ndikukula kwa khanda kapena khanda. Ngati nkosatheka kuletsa kugwiritsa ntchito mankhwalawa panthawi yoyamwa, ndiye kuti muyenera kusiya kapena kusiya kuyamwitsa kuti musavulaze mwana.

Muubwana

Mankhwala ndi oletsedwa kugwiritsidwa ntchito osakwana zaka 18. Ichi ndichifukwa cha kuchuluka kwa thioctic acid pa metabolism, komwe kumatha kubweretsa zotsatira zosalamulirika m'thupi mwa ana ndi achinyamata. Musanagwiritse ntchito, muyenera kufunsa dokotala nthawi zonse ndikupeza chilolezo pambuyo popenda bwino ziwalo ndi machitidwe.

Thiogamm kwa kuwonda

Lipoic acid ndi antioxidant, imathandizira njira ya metabolic, imakongoletsa kapamba, kotero angagwiritsidwe ntchito kuchepa thupi. Imayendetsa kuchuluka kwa shuga, imachepetsa kukalamba, imayenda bwino, imathandizira kusintha kwa chakudya chamagetsi kukhala mphamvu, komanso imalimbikitsa kukhathamiritsa kwa mafuta acids. Komanso, asidi amalepheretsa kuchuluka kwa maselo aubongo, omwe amachititsa kuti munthu akhale ndi njala, izi zimathandizira kuti azilakalaka.

Ndi zaka, kupanga lipoic acid kumachepetsa, motero umagwiritsidwa ntchito ngati chowonjezera chokwanira. Mankhwala a Thiogamma amatha kugwiritsidwa ntchito pakuchepetsa thupi, koma malinga ndi kulimbitsa thupi kawirikawiri. Nutritionists akulangizidwa kuti atenge 600 mg ya mankhwala othandizira / tsiku lisanayambike kapena litatha chakudya cham'mawa, palimodzi ndi chakudya chamagulu, mutatha masewera olimbitsa thupi kapena mutatha kudya. Pamodzi ndi kudya ayenera kuchepetsa calorie kudya.

Zotsatira zoyipa

Mukamamwa Thiogamma, mavuto osiyanasiyana amatha kuchitika. Zodziwika kwambiri ndi:

nseru, kutsegula m'mimba, kusanza, kupweteka m'mimba, chiwindi, gastritis,
intracranial hemorrhage,
kupuma, kupuma movutikira,
thupi lawo siligwirizana, anaphylactic mantha, zotupa pakhungu, kuyabwa, urticaria,
kuphwanya kukoma
kuchepa kwa magazi ndende - hypoglycemia: chizungulire, kupweteka kwa mutu, kutuluka thukuta, kusokonezeka kwa mawonekedwe.

Zolemba za Thiogamma

M'malo mwa Thiogamma mumaphatikizanso mankhwala omwe ali ndi zinthu zomwezo. Mafuta a mankhwalawa:

Lipoic acid ndimakonzedwe a piritsi, analogue mwachindunji,
Berlition - mapiritsi ndi njira yokhazikika yokhazikika pa thioctic acid,
Tialepta - mbale ndi njira yothandizira matenda a matenda ashuga, mankhwalawa,
Thioctacid turbo ndi mankhwala a metabolic omwe amachokera ku alpha lipoic acid.

Mtengo wogula Tiogamma udzatengera mtundu wa mankhwalawo, kuchuluka kwa mankhwalawo ndi pulojekiti yamakampani omwe amagulitsa komanso opanga. Mitengo yotsika mtengo ku Moscow:

Kulowetsedwa Solution 150 ml

Mapiritsi a 600 mg, 30 ma PC.

Mapiritsi a 600 mg, 60 ma PC.

Njira yothetsera kulowetsedwa 50 ml, Mbale 10

Alla, wazaka 37. Mankhwala a Tiogamma adalangizidwa ndi mzanga yemwe adachepetsa thupi kuposa kuzindikira. Anatenga ndi chilolezo cha adotolo, ataphunzitsidwa, kuwonjezera pazakudya. Ndinayamba kumwa mapiritsi ndikudya momwemo, kwa mwezi umodzi ndinataya ma kilogalamu asanu. Zabwino kwambiri, ndikuganiza kuti ndibwereza maphunzirowa koposa kamodzi.

Aleksey, wazaka 42. Kutengera zakumbuyo zakumwa zoledzeretsa, ndinayamba polyneuropathy, manja anga anali kugwedezeka, ndinayamba kuvutika ndi kusintha kwa mikhalidwe pafupipafupi. Madotolo adati tiyenera choyamba kuchiza uchidakwa, ndikuchotsa zotsatirapo zake. Pa gawo lachiwiri la zamankhwala, ndidayamba kumwa njira ya Tiogamma. Amathana bwino ndi vuto la neuropathy, ndidayamba kugona bwino.

Olga, wazaka 56 ndimadwala matenda a shuga, motero ndimakonda kuchita neuropathy. Madokotala adalemba Tiogamm kuti akhale ndi prophylaxis, komanso kusintha kwa insulin. Ndimamwa mapiritsi molingana ndi malangizo ndikuwona kusintha - ndakhala wodekha, sindikhala ndi nkhawa usiku komanso m'mawa, manja anga samagwedezeka chifukwa cha nkhawa.

Larisa, wazaka 33 Kuchokera kwa mzanga kuchokera ku cosmetology, ndinamva lipangiri: gwiritsani ntchito mankhwala a lipoic acid pama ampoules kuti muchepetse mawanga azaka ndi makwinya omwe amayamba. Ndidafunsa adotolo kuti alembe kalata ndikuigula, ndikuigwiritsa ntchito madzulo: nditatha kusamba, ndidagwiritsa ntchito yankho m'malo mwa tonic, kenako zonona pamwamba. Patatha mwezi wathunthu, mawanga adayamba kuzimiririka, khungu limasuluka.