Kuchulukana kwa Orsoten

Posachedwa, kufunikira kwa mapiritsi a Orsoten kwakhala kwakukulu kwambiri m'mafakisi. Buku lamauphunziroli lili ndi malingaliro ogwiritsira ntchito, ngati kuli kotheka, ataya mapaundi owonjezera. Momwe mungagwiritsire ntchito mankhwalawa moyenera, chifukwa chiyani imagwira ntchito komanso imawononga ndalama zingati? Tiyeni tiyese kuzilingalira, tikulingalira za malangizo omwe aperekedwa ndi wopanga.

Mawonedwe onse

Monga momwe tikuwonera potsatira malangizo, mukamachepetsa thupi, "Orsoten" imagwira ntchito chifukwa cha zinthu zina zomwe zimalepheretsa ntchito ya michere ya lipase. Izi zimakhudza ntchito yam'mimba, zimathandizira kuchotsa mapaundi owonjezera, kuchiritsa kunenepa kwambiri. Chogwiritsidwachi ndi chamakono, chawoneka pamashelefu posachedwa, chikuwoneka kuti chothandiza kwambiri komanso chodalirika, ndipo wopanga amalimbikitsidwa kuti azigwiritsidwa ntchito chifukwa cha zovuta zomwe zimatsatana ndi njira yochizira. Zowona, kuti mupewe kuwoneka kosasangalatsa, "Orsoten" sayenera kugwiritsidwa ntchito mongotsatira malangizo, komanso moyang'aniridwa ndi dokotala. Dokotala wodziwa bwino amakuthandizani kusankha njira yabwino kwambiri, chifukwa mapulogalamu onse omwe afotokozedwa m'malangizo sioyenera aliyense.

Mbali yodziwika, monga ikusonyezedwera mu malangizo a mapiritsi a Orsoten, ndi kutalika kwa mphamvu ya mankhwalawa. Chogulitsachi chimakhudza thupi la munthu mosiyana ndi mankhwala a Xenical, koma chimakopa chidwi chotsika mtengo kwambiri - pafupifupi ma ruble 5,000,000 phukusi lililonse. Kupezeka kwa anthu wamba, ndikuthandizira kuchotsa mapaundi owonjezera, ngati kuli koyenera, ndikosangalatsa mabwalo akulu kwambiri. Nzika zonenepa kwambiri zitha kuyamba kulandira chithandizo pakadali pano, palibe chifukwa chobisira zamtsogolo ngati ndalama zaulere zikuwoneka. Izi zikutanthauza kuti chiwopsezo cha zovuta chifukwa cha kunenepa kwambiri chimachepetsedwa.

Gwiritsani ntchito mwanzeru

Monga tawonetsera mu ndemanga, malangizo, "Orsoten" amawonetsa zotsatira zabwino ngati mugwiritsa ntchito mankhwalawa, kutsatira zakudya zabwino zomwe dotolo woyenerera amaganizira ndi zomwe wodwalayo ali nazo. Lingaliro lalikulu la pulogalamu yodyetserayi ndikuchepetsa zovuta zamafuta amnyama zomwe zimalowa mthupi kudzera mu chakudya. Kugwiritsira ntchito kwa mankhwala ofotokozedwawo komanso kuchepetsedwa kwa zopatsa mphamvu za calorie zotsekemera zimatilola kukwaniritsa kuwonda kwakukulu m'miyezi isanu ndi umodzi yokha, ndikukhalabe ndi zotsatira zokhazikika kwanthawi yayitali.

Kugwiritsa ntchito moyenera kwa "Orsoten" malinga ndi malangizo kumangoleketsa kulemetsa, komanso kukwaniritsa kusintha kwina m'thupi. Chodziwika kwambiri ndi kuchepa kwa kuchuluka kwa madzi am'magazi m'magazi a cholesterol ambiri, ochepa mapuloteni a lipid. Ndi penti iyi yomwe imatchedwa "cholesterol yoyipa" m'mabuku asayansi otchuka ndipo imalumikizidwa ndi chiwopsezo cha matenda a atherosulinotic. Kugwiritsa ntchito moyenera kwa "Orsoten" kumathandizira kuti magazi akhale achilengedwe, kupewa kupewa matenda ambiri, kuphatikizapo omwe amawopsa.

Chifukwa chiyani izi zimagwira?

Monga tafotokozera m'malamulo ogwiritsira ntchito, Orsoten ali ndi orlistat. Pulogalamuyi imathandizira pakukhudzana ndi mankhwala komwe kumachitika m'thupi la munthu, zomwe zimapangitsa kuti thupi lichepe. Pulogalamuyo ndiyopadera kwambiri, ilibe ma fanizo ophatikizira, imalepheretsa ma enzymes a lipase, m'dera lomwe ntchito yake ndi hydrolysis ya lipid mankhwala ophatikizika kwambiri.

Orlistat idatsimikizira kugwira ntchito kwake ngati njira yowongolera mosalekeza thupi. Monga momwe tikuwonera potsatira malangizo ogwiritsira ntchito Orsotene Slim, kugwiritsa ntchito moyenera mankhwalawa kumakupatsani mwayi woyamba kukwaniritsa kulemera kumene mukufuna, kenako khalani ndi chizindikirocho kwa nthawi yayitali. Kugwiritsa ntchito moyenera mankhwalawa kumalepheretsanso kukonzanso kwakukulu. Kuyesedwa kwa kachipatala kwatsimikizira kuti pulogalamu yothandizirana ndi kuphatikizidwa kwa dzinali ndiyothandiza kupewa matenda ambiri, zomwe zimayambitsa ngozi zomwe zingayambitse matenda. Pazinthu zofunikira kwambiri, ndikofunikira kudziwa kupewa kwa cholesterol yayikulu m'magazi, shuga, kuthamanga kwa magazi. Orlistat imathandizira kuwongolera kuchuluka kwa insulin mthupi, imachepetsa shuga. Zowona, zabwino zitha kuchitika potsatira malangizo a dokotala ndi wopanga. Kuwatsata, m'miyezi isanu ndi umodzi yokha mutha kuchepetsa kuchuluka kwa mafuta a visceral ndikukwaniritsa kuchira kwathunthu kwa thupi.

Momwe mungasinthe?

Mwa njira zina, malangizo a Orsoten ndi mawonekedwe awo ndi ofanana:

Mayina awiri ofanana amaperekedwa pamashelefu apachipatala: "Orsoten" ndi "Orsoten Slim". Mankhwala onse omwe atchulidwa amafuna kuti achepetse kulemera kwakukulu, adapangidwa kuti azigwiritsidwa ntchito moyang'aniridwa ndi dokotala, ndipo amapezeka pakamwa pakukonzekera pakamwa. Malinga ndi malangizo ogwiritsira ntchito, "Orsotin Slim" amasiyana ndi kutulutsidwa kwapadera mu ndende yotsikira yomwe imakhudza lipase. Kuchuluka kwake ndi kochepera kuposa ku Orsoten, theka.

Kodi ntchito?

Malangizo ogwiritsira ntchito mankhwalawa - "Orsotene Slim" ndi "Orsoten" - akuwonetsa kuti mankhwalawa adapangira anthu omwe adokotala adziwa kunenepa kwambiri. Kunenepa kwambiri ndi chidziwitso chokwanira kuti muyambe kugwiritsa ntchito zinthu izi. Kuti adziwe kuchuluka kwa kulemera kwake komwe kumachokera muzochitika, poika, dokotala amayang'ana wodwalayo, ndikuwonetsa mndandanda wazomwe zimayimira thupi. Ngati chizindikiro ndichipamwamba kuposa 28 kg pa mita imodzi ya thupi, titha kulankhula zambiri. Kunenepa kwambiri kumadziwika ngati gawo ili liposa 30 magawo. Monga tingaonere kuchokera ku kafukufuku waposachedwa kwambiri, mpaka pafupifupi theka la nzika zathu zakhala zikuvutika ndi kunenepa kwambiri, ndipo opitilira theka la nzika zino ndi onenepa kwambiri.

Malangizo ogwiritsira ntchito "Orsotene" pakuchepetsa thupi ali ndi kutchulidwa kwa mphamvu ya mankhwala munthawi ya chithandizo. Kutalika kwa pulogalamu yotero, mlingo wake umasankhidwa ndi adokotala, kuyang'ana momwe thupi la wodwalayo limagwirira ntchito, ndi zina zake. Orsoten adapangira mankhwalawa kunenepa ngati gawo la pulogalamu yonse. Dokotala amadziwitsa kuchuluka kwa zochita zolimbitsa thupi kwa wodwalayo, amakhazikitsa malamulo azakudya, amapatsa wodwala chakudya chamagulu chama calorie. Izi zikutanthauza kuti muyenera kudya zokhazo zomwe zimapangitsa kuti mafuta ochepa a nyama azikhala ochepa.

Zomwe zili mumafakisi?

Monga akunenera malangizo omwe agwiritsidwe ntchito, Orsoten adapangira pakamwa kuti azigwiritsa ntchito. Pamalo ogulitsa mankhwala mutha kuwona makatoni okhala ndi matuza okhala ndi makapisozi. Chosakaniza chophatikizika chakuphatikizidwa mu gelatin. Mitundu yake ndi yoyera komanso yachikaso. Kudzaza kwamkati - ma granules a kukula kwama microscopic kapena osakanikirana ndi michere ndi zinthu zotere.

Monga momwe malangizo a Orsoten angagwiritsire ntchito, 120 mg ndi muyezo wa gawo lomwe limagwira ntchito kapisozi imodzi yamankhwala. Kuphatikiza pa orlistat, popanga makonzedwe, zinthu zothandizira zinagwiritsidwa ntchito - gelatin, yomwe imayendetsa njira yapadera yoyeretsera, madzi, cellulose, cellulose, titanium dioxide. Makamaka mosamala ndi mndandanda wazinthu zomwe zimagwiritsidwa ntchito popanga mankhwala ndizofunikira kwa anthu omwe ali ndi vuto lodana ndi tsankho, tsankho la mankhwala aliwonse omwe amagwiritsidwa ntchito pamakampani ogulitsa mankhwala. Ngati pali ziwopsezo, hypersensitivity to okuthile, dokotala yemwe amapereka mankhwala a "Orsoten" ayenera kuchenjezedwa za izi. Makapisozi amawaunjikira matuza okhala ndi masamba 7 mpaka 21. Kuchuluka kwa zinthu zomwe zili mu phukusi zikuwonetsedwa kunja kwa bokosi la makatoni.

Momwe mungagwiritsire ntchito?

Malangizo ogwiritsira ntchito "Orsotene" ali ndi malangizo omveka bwino okhudzana ndi magwiritsidwe ntchito a mankhwalawo. Nthawi zambiri, mankhwalawa amagwiritsidwa ntchito musanadye chakudya, pakudya kapena musanadye chakudya. Kusintha bwino, kupewetsa kuyamwa kwa mankhwalawa, kumatsukidwa ndi madzi okwanira. Pakupita tsiku limodzi, Orsoten amatengedwa katatu kapisozi iliyonse. Osagwiritsa ntchito zoposa 360 mg yogwira pophika maola 24. Monga momwe mayesero azachipatala asonyezera, kuwonjezera kuchuluka kwa mankhwalawa sikuchulukitsa mphamvu ya mankhwalawa.

Malangizo ogwiritsira ntchito "Orsotene" akuwonetsa kufunikira kwa maphunziro a mankhwala. Kutalika kwa pulogalamuyo sikupitilira miyezi isanu ndi umodzi. Kuyang'aniridwa kwa achipatala. Ngati miyezi itatu kuyambira chiyambi cha chithandizo palibe momwe wodwalayo akumvera, kuchepa thupi kumakhalapo kapena kusinthasintha mkati mwa 5% ya magawo oyambira, katswiri wazakudya ayenera kuthandizidwa. Monga lamulo, adokotala akuwonetsa kuti mankhwalawo athetse ena, ndikusankha othandiza kwambiri. Mwina adokotala angalimbikitse kusiya kugwiritsa ntchito mankhwalawa kuti muchepetse kunenepa ndikugwiritsa ntchito njira zina zowongolera thupi.

Njira zophatikizika

Malangizo ogwiritsira ntchito "Orsotene" ali ndi chisonyezo chakufunika kogwiritsa ntchito mankhwalawa limodzi ndi maphunziro apaderadera azakudya. Popanda pulogalamu yamadyedwe, kupeza zotsatira zabwino sikungathandize. Muyenera kusankha zakudya mukamakambirana ndi wazamankhwala oyenera. Kuphatikiza apo, muyenera kusintha moyo wanu, kuchita masewera olimbitsa thupi nthawi zonse (moyenera malire). Madokotala amalimbikitsa kuyamba ndi masewera olimbitsa thupi kuchokera ku gulu lazolimbitsa thupi, ndikuzichita pafupipafupi, pang'onopang'ono kulola thupi kuti lizolowere kuchita izi. Kuphatikiza kwamtolo woyenera komanso kudya zakudya zochepa zamafuta sikuti kumangothandiza kugwira bwino ntchito kwa Orsoten, chikhala chanzeru kutembenukiranso ngakhale isanayambike maphunziro, chifukwa zimayambitsa maziko abwino ochepera thupi popanda kuvulaza machitidwe a thupi.

Monga tikuwonera kuchokera pakuwunikira, malangizo ogwiritsira ntchito, Orsoten amapereka zotsatira zabwino ngati wodwalayo azitsatira zakudya zopanda mafuta. Chifukwa chake, zokonda ziyenera kuperekedwa kokha ku zinthu zomwe ma lipids sizoposa 30 g. Zimatsimikiziridwa kuti zipitirire gawo ili. Chifukwa chake ndikofunikira kupanga zakudya kuti lipids ilowe mthupi mosiyanasiyana tsiku lonse, ndiye kuti, zakudya zamafuta zimapezekanso m'zakudya zonse.

Zoyambitsa ndi zotsatira zake

Malinga ndi akatswiri, kuchuluka kwa maselo amafuta pansi pa khungu nthawi zambiri kumayamba chifukwa cha kuchuluka kwa chakudya chambiri komanso lipids mthupi. Ndemanga, malangizo ogwiritsira ntchito Orsoten amawonetsa kuti mankhwalawa alibe mphamvu pa mankhwala ena kupatula lipids. Ngati wodwalayo amachepetsa kuchuluka kwa zinthuzi m'zakudya, koma kudya maswiti ambiri, zopangidwa ndi ufa, sizokayikitsa kuti angachotse kulemera kowopsa. Kuti mupeze zotsatira zoyenera, muyenera kuyesetsa kusintha zochita zanu. Mwa njira, kuyambira machitidwe aposachedwa kwambiri zikuwonekeratu kuti vuto la mapaundi owonjezera silidutsa ngakhale azungu omwe amakhala ndi moyo wabwino kwambiri. Izi zikuwonetseratu kuti nthawi zambiri sizinthu zokhazo zomwe zimachokera ku nyama zomwe zimabweretsa kulemera.

Monga tawonetsera pakuwonetsa kuchepa kwa mafuta pamtengo wa "Orsotene" (malangizo ogwiritsidwira ntchito nthawi zonse amakhazikika phukusi ndi mankhwalawo), mankhwalawo ndiokwera mtengo - pafupifupi ma ruble 550 pa bokosi lililonse, koma salola kuthetsa vutoli potenga makapisozi kamodzi. Samalani izi komanso akatswiri azakudya omwe amapereka mankhwala kuti akonze zolemetsa za kasitomala. Kuti musunge momwe mungakwaniritsire, ndizofunikira mtsogolo kutsatira pulogalamu yochepa yazakudya, kuchita masewera olimbitsa thupi moyenera. Njira yoyenera, yothandiza komanso yothandiza kwambiri ndikusintha kwa moyo wathanzi komanso zosavuta kudya ngakhale musanamwe mankhwalawa, kupitiriza kwa mchitidwewu kumapeto kwa maphunzirowa.

Mwambo wapadera

Monga mukuwonera pakupenda, malangizo ogwiritsira ntchito, "Orsoten" angagwiritsidwe ntchito pochotsa kunenepa kwambiri mu ukalamba. Mankhwalawa ndi oyenera kuthandizira anthu omwe ali ndi vuto linalake. Kuyesedwa kwawonetsa kuti mawonekedwe omwe amagwira ntchito samakhudza chiwindi ndi impso, chifukwa chake, mavuto azaumoyo satanthauza kusintha kwa mankhwala omwe amagwiritsidwa ntchito mu chakudya. Komabe, pamatenda aliwonse owopsa komanso osachiritsika, wodwalayo ayenera kudziwitsa dokotala ngati mawonekedwe ake akuwongolera kusintha kapena kusintha kwa mawonekedwe a phula.

Ndipo ngati zochuluka?

Monga ndi analogues, malangizo ogwiritsira ntchito Orsoten ali ndi malamulo ngati bongo la yogwiritsa ntchito lambiri. Ngati, mwa mwayi, wodwalayo atenga gawo lochulukirapo la chakudya m'zakudya, kuyang'aniridwa kwachipatala kwa anthu kuli kofunikira masana kuyambira nthawi yomwe mwambowu uchitike. Kuphatikiza apo, muyenera kufunsa dokotala. M'masiku awiri otsatirawo, amachepetsa kudya kwa inhibitory lipase mu chakudya, mpaka zomwe zimatengedwa zitachotsedwa kwathunthu m'thupi.

Mayeso azachipatala asonyeza kuti mankhwala osokoneza bongo amatha kuyambitsa mavuto obwera chifukwa chakuletsa ntchito ya michere yam'mimba, kapamba. Onse posachedwa amadzitopetsa okha, zosintha zimasinthiratu. Ngati mulingo woyenera wothandizila patsiku umadutsa kwambiri, mwayi wocheza ndi thupi nthawi zambiri sikukula ngakhale mukufufuza nthawi yayitali. Kutchulidwa kwa izi kuli mu malangizo ogwiritsira ntchito kuchepa kwa thupi "Orsoten", analogues zochokera pakompyuta imodzi yomwe imagwira ntchito. Mayina a mankhwala ena osokoneza bongo aikidwa pansipa.

Kodi chikuchitika ndi chiani mthupi?

Monga ma analogu ena potengera orlistat, "Orsoten" (ndemanga, malangizo ogwiritsira ntchito amatsimikizira izi) zimakhudza magwiridwe antchito am'magazi a anthu. Mothandizidwa ndi polo yogwira, njira zomwe zimachitika m'matumbo ang'ono ndi kusintha kwam'mimba. Orlistat imatha kuchepetsa ntchito zophatikizana ndi lipid. Poterepa, chigawochi chimakhudzana ndi ma enzymes opangidwa ndi kapamba, m'mimba. Kuphatikiza komweku kumapangitsa kuti kuyimitsa ntchito ya enzymatic. Izi zimachitika makamaka chifukwa cha kukhalapo kwa malo olumikizirana, kuphatikizapo ma serine lipases.

Ma Enzymes omwe amasiya kugwira ntchito sangathe kudzipatula ma triglycerides kukhala opanga, mafuta a mafomu achilengedwe. Izi zikutanthauza kuti palibe zida zosavuta zomwe kudzera m'makoma amatumbo zimatha kulowa mkati. Lipids yomwe siinapangidwe ndi hydrolysis sangakhale nayo adsorbed, chifukwa chake, minofu yathupi imayang'anizana ndi kusowa kwa ma calorie, omwe amachititsa kuti omwe adziunjikira kale adye. Popita nthawi, njirayi imayambitsa kutsika kwa kuchuluka kwa mafuta ochulukirapo.Kuchepetsa thupi nthawi zambiri kumawonedwa mwachangu.

Mawonekedwe akugwiritsidwa ntchito

Monga momwe mayesero azachipatala asonyezera, pulogalamu yoyenera yogwiritsira ntchito mankhwalawa imakhala ya tsiku ndi tsiku, katatu katatu pa kapisozi. Nthawi yomweyo, mafuta omwe amapezeka muzakudya amamwa kwambiri kotala moyipa. Kuchita kwake kumangokhala kwawoko, mankhwalawa samamwetsa, samakhudza thupi mwadongosolo. Choyambirira chikuchitika pakatha masiku awiri chiyambireni chithandizo. Izi zikuwonekera pazomwe zili m'matumbo, zimakhala ndi mafuta ochulukirapo kuposa kale. Ngati mulephera kugwiritsa ntchito mankhwalawa, pakatha masiku atatu, kuchuluka kwa mafuta m'matumbo am'mimba kumakhala kwabwinobwino. Monga momwe tikuwonera pakuwunika ndi malangizo oti agwiritse ntchito, kutsitsa "Orsoten" ndi kothandiza komanso kotetezeka.

Mphamvu zamankhwala

"Orsoten", kamodzi m'thupi la wodwalayo, suli ndi mbiri. Maola asanu ndi atatu pambuyo poti gawo lifika pamlingo wokwanira mu magazi, kuphatikizika koperewera kwa gawo lothandiziralo kumawonedwa, koma ndilochepa kwambiri mwakuti ngakhale njira zolondola kwambiri masiku ano sizimalola kuti zidziwike. Orlistat sikhala ndi michere yachilengedwe. Chipangizocho chiribe dongosolo, chili 99% cholumikizidwa ndi mapuloteni am'madzi. Mu ndende yaying'ono, orlistat imatha kulowa m'magazi ofiira. Njira yopangidwira imapangidwira matumbo a matumbo, minyewa yam'mimba, imayambitsa mapangidwe a metabolites osagwira. Mpaka 67% ya Orsoten amasiya thupi ndikutulutsa m'matumbo, 83% - osasinthika. Pafupifupi awiri peresenti amawachotsa impso. Kutalika kwa kuyeretsa kwathunthu kwa thupi kuchokera ku chinthu chogwira kuyambira masiku atatu mpaka asanu.

Nthawi zina simungathe

Contraindication pamaphunzirowa ndi tsankho, hypersensitivity iliyonse ya mankhwala omwe amagwiritsidwa ntchito popanga mankhwalawa, komanso chifukwa chosavomerezeka ndi bile, kutuluka, chithaphwi. Simungagwiritse ntchito "Orsoten" ndi kuthamanga kwa magazi, cholesterol yowonjezera m'magazi, komanso malabsorption syndrome ya galactose, glucose.

Zotsatira zosasangalatsa: zomwe muyenera kukonzekera?

Zotsatira zoyipa zilizonse zomwe mankhwala angayambitse zimalembedwa mu malangizo omwe angagwiritsire ntchito. Amadziwika kuti kuyanjana ndi mankhwalawa ndikotheka, odwala ena amamva chizungulire, ndipo chithandizo chokha chimayendetsedwa ndi kutopa, kufooka kwa thupi. Orlistat imatha kuyambitsa kuyipa kwam'mimba, m'mimba. Ngati Orsoten amagwiritsidwa ntchito pakuchepetsa thupi, pamakhala chiwopsezo cha kusokonezeka kwa chopondapo, kuphatikizapo kusayenda, komanso mafuta am'mimba kuchokera m'matumbo. Odwala ena adazindikira ululu wam'mimba (m'munsi). Orlistat imatha kudzutsa kuchuluka kwa mafuta mu chopondapo, kukakamira pafupipafupi kufooka, kusinthitsa kapangidwe ka mpweya, ndipo mipweya imagawikidwanso m'magawo ang'onoang'ono. Pali chiopsezo chotenga m'mimba mukamagwiritsa ntchito mankhwalawa. Mwambiri, pamtengo wake, Orsoten (malangizo ogwiritsira ntchito ndi analogues amafanana) nthawi zambiri amaloledwa.

Osowa kwambiri, "Orsoten" amachititsa kuti magazi azituluka. Izi zimadziwika kuti ndizotetezeka, siziyenera kuyambitsa mantha. Amadziwika kuti nthawi zina, mankhwalawa amakulitsa kapena adayambitsa diverticulitis, hepatitis. Potengera momwe ntchitoyo ingagwiritsidwire ntchito, ma gallstones amatha kuoneka.

Zoyang'ana?

Mayeso a Laborator awonetsa kuti Orsoten (ndi analogues, malangizowo amatsimikizira izi) atha kuchepetsa kuchuluka kwa prothrombin. Izi zitha kuwululidwa pakufufuza kwa magazi mu labotale. Nthawi zina, pamakhala chiopsezo cha mkondo wamphamvu.

"Orsoten" akhoza kuphatikizidwa ndi mankhwala osiyanasiyana, koma ndikofunikira kudziwitsa adotolo za mankhwala onse omwe wodwala amamwa. Makamaka, ndende ya yogwira thupi mthupi ikhoza kusintha ngati wodwala agwiritsa ntchito mankhwala kuti achepetse magazi. Izi zimanenedweratu ngati munthu akalandira chithandizo cha mankhwala osokoneza bongo a warfarin. Ngati wodwala amagwiritsa ntchito mankhwala okhala ndi cyclosporine, ndizotheka kuchepetsa mphamvu ya mankhwalawa akamagwiritsidwa ntchito nthawi yomweyo ndi Orsoten.

Kupanga ndi mawonekedwe a kumasulidwa

Gulu la mankhwala ndi mankhwala: mankhwala ochizira kunenepa - zoletsa zam'mimba lipases.

Mtundu wapadera wapadera woonda msanga umapezeka mu kapangidwe ka kapisolo, komwe ndi kovomerezeka. Mkati mwa zotengera zamafuta achikasu za gelatin pali timiyala tating'ono ta microscopic kapena chisakanizo cha granules ndi ufa wazinthu zomwe zimagwira.

• 1 kapisozi muli 120 mg wa yogwira mankhwala (orlistat). Monga zida zothandiza popanga mankhwala opangira mankhwala, madzi oyeretsedwa amagwiritsidwa ntchito ngati gelatin, hypromellose, cellcrystalline cellulose ndi titanium dioxide.

Makapisozi amaperekedwa m'matumba a blister (zidutswa 7 kapena 21 zidutswa chilichonse).

Kodi chimathandiza Orsoten ndi chiyani?

Orsoten amadziwika kuti azitha kuchiza kwa odwala omwe ali ndi kunenepa kwambiri chifukwa cha kuchuluka kwa thupi (BMI) ≥30 kg / m 2 kapena onenepa kwambiri (BMI ≥28 kg / m 2), kuphatikiza odwala omwe ali pachiwopsezo chokhudzana ndi kunenepa kwambiri, kuphatikiza ndikutsatira koyenera Zakudya zochepa zopatsa mphamvu.

Ndikotheka kupatsa Orsoten nthawi yomweyo mankhwala a hypoglycemic komanso / kapena zakudya zochepa zopatsa mphamvu zamagulu 2 a shuga onenepa kwambiri kapena onenepa kwambiri.

Zambiri zamankhwala

World Organisation of Gastroenterologists imayika orlistat ngati mankhwala othandiza kuchepetsa kunenepa kwambiri.

M'mayesero azachipatala, mankhwalawa adapangitsa kuchepa kwakukulu kwa kulemera kwa thupi mu 75% ya odwala odzipereka. Kwa milungu 12 ya chithandizo, odwala adatha kutaya mpaka 5% ya kulemera koyamba. Zotsatira zapamwamba (mpaka 10%) zimawonedwa mwa omwe amaphatikiza kugwiritsa ntchito mankhwalawa ndi zakudya zochepa zopatsa mphamvu komanso zolimbitsa thupi.

Pakati pa mayesowa, zotsatira zina zabwino za chithandizo cha mankhwala zidadziwika. Makamaka, odwala omwe ali ndi matenda oopsa, kuchepa kwa kuthamanga kwa magazi kunawonedwa:

• systolic ("kumtunda") - pafupifupi 12.9 mm RT. Art.
• diastolic ("m'munsi") - mwa 7.6 mm RT. Art.

Onse odzipereka adawonetsa kusintha kwa metabolidi ya lipid. Patatha milungu 24 chiyambireni maphunziro, mankhwalawa amadzimadzi ambiri komanso otsika a lipoproteins (LDL) amatsika m'magazi.

Kafukufuku wambiri atsimikizira kuti orlistat imathandizira kupewa kapena kuchepetsa kufalikira kwa matenda a shuga II. Odwala omwe ali ndi vuto la kulolera glucose akamamwa, minyewa ya insulin imayamba kuyenda bwino. Odwala omwe ali ndi matenda ashuga okhazikika kale, chithandizo chokwanira chimalola kuchuluka kwa ma hypoglycemic othandizira.

Zotsatira za pharmacological

Kuchita kwa Orsoten pakuchotsa mapaundi owonjezera kumawonetsedwa ndi chinthu chomwe chikugwidwa - orlistat. Awa ndi mankhwala omwe amagwiritsidwa ntchito ngati mankhwala komanso Zakudya zamagulu makamaka zamafuta. Ndiye, kulowa m'mimba, komwe kumagwira ntchito zonse zofunika kumeneko:

• Imaletsa ntchito ya lipase - ma enzyme omwe amayendera mafuta,
• Zotsatira zake, mafuta samatenga thupi, chifukwa amakhala osalowerera ndi lipase.
• thupi limayamba kugwiritsa ntchito mafuta omwe adalipo kale, kuphatikiza visceral, chosungidwa "posungira",
• palibe mafuta m'thupi - palibe owonjezera mapaundi.

Makina ochitira Orsoten ndi ophweka kwambiri, koma mukupepuka kumeneku kuti ndi wanzeru. Kukhudza pang'ono njira zomwe zimachitika mthupi, zimapangitsa kuti ziwonongeke pang'ono.

Malangizo ogwiritsira ntchito

Malinga ndi malangizo ogwiritsira ntchito, mlingo umodzi wa Orsoten ndi 1 ziphuphu. (120 mg).

Kaphidwe kamtsuko kamatsukidwa ndi madzi, kumamwa pakumwa nthawi yomweyo musanadye chakudya chachikulu chilichonse, mukamadya kapena osaposa ola limodzi mutatha kudya. Ngati chakudya chidatsitsidwa kapena ngati chakudya mulibe mafuta, mutha kudumpha orlistat.

• Kuchulukitsa kwa mankhwalawa sikuwonjezera kuchuluka kwa achire. Mayeso azachipatala awonetsa kuti zochuluka zowonjezera zomwe zimagwira ntchito zimachotsedwa mwachilengedwe mkati mwa masiku 5. Kutalika kwa nthawi ya mankhwala kumatsimikiziridwa ndi dokotala, nthawi zambiri amachokera ku miyezi iwiri mpaka itatu. Ngati m'masiku 60-70 oyamba kuchepa thupi ndi ochepera 5%, mankhwalawa amayimitsidwa.

Kusintha kwa Mlingo sikofunikira kwa okalamba kapena odwala omwe ali ndi vuto la chiwindi kapena impso. Chitetezo ndikuyenda bwino kwa orlistat pochizira ana ndi achinyamata ochepera zaka 18 sizinakhazikitsidwe.

Contraindication

Malinga ndi malangizo, Orsoten sangasankhidwe ndi:

• cholestasis
• Hypersensitivity pamagulu omwe amaphatikizidwa ndi mankhwala,
• aakulu malabsorption syndrome,
• mimba ndi mkaka wa m`mawere

komanso osakwana zaka 18.

Zotsatira zoyipa

Orsoten amatha kuyambitsa zovuta zina - makamaka kuchokera m'mimba. Pochepetsa dongosolo la mawonekedwe awo, izi zitha kukhala:

• chisangalalo
• ukufalikira
• dyspepsia
• Mafuta amadzimadzi ochokera ku rectum,
• pafupipafupi kukakamira,
• fecal kulephera.

Nthawi zina, kufooka kwapafupipafupi, kupweteka kwam'mimba, kupweteka kwa mutu, kusamba kwa msambo, kuyanjana ndi matendawa kumawonedwa. Nthawi zambiri, mavuto amayambika pa gawo loyambirira la chithandizo, kenako ndikutha.

Bongo

Ndemanga za madotolo ku Orsoten zilibe chidziwitso chokhudza milandu yambiri ya chida ichi.

Mlingo umodzi wa orlistat pa mlingo wa 800 mg kapena mpaka 400 mg katatu patsiku kwa milungu iwiri sizinayende limodzi ndi zovuta zoyipa.

Ngati bongo wa mapiritsi a Orsoten, kuyang'anira wodwala tsiku lonse ndikulimbikitsidwa.

Malangizo apadera

Pa mankhwalawa, tikulimbikitsidwa kuti mutenge maultivitamini osiyanasiyana kuti muwonetsetse kuti muzikhala ndi zakudya zokwanira. Odwala ayenera kutsatira malangizo azakudya. Zakudya ziyenera kukhala zopatsa mphamvu, zopatsa mphamvu pang'ono komanso zopatsa mphamvu zopitilira 30% zamafuta. Zakudya za tsiku ndi tsiku zamafuta zimayenera kugawidwa m'magulu atatu azakudya zazikulu.

Orsoten imagwira ntchito kwa nthawi yayitali yoongolera thupi (kuchepetsa thupi, kuisunga pamlingo woyenera ndikuletsa kupewa kuwonjezeranso thupi). Chithandizo cha mankhwalawa chimawongolera chiwonetsero cha zovuta ndi matenda omwe amayenda ndi kunenepa kwambiri (kuphatikizira kulekerera kwa glucose, hypercholesterolemia, matenda oopsa, hyperinsulinemia, mtundu 2 shuga mellitus), ndikuchepetsa kuchuluka kwamafuta a visceral.

Chifukwa cha kuchepa thupi kwa odwala omwe ali ndi mtundu wa matenda a shuga 2, kusintha kwa chiphuphu cha carbohydrate metabolism nthawi zambiri kumawonedwa, komwe kungapangitse kuchepa kwa mlingo wa mankhwala a hypoglycemic.

Chiwopsezo cha zotsatira zoyipa zamagetsi chimatha kuchuluka mukamamwa Orsoten motsutsana ndi zakudya zamafuta. Mankhwalawo amathetsedwa ngati, mkati mwa masabata 12 kuyambira pomwe mankhwalawa adayamba, kulemera kwa thupi sikunatsike kupitilira 5% ya choyambirira.

Kuchita ndi mankhwala ena

Mukamagwiritsa ntchito Orsoten nthawi yomweyo ndi:

• pravastatin - kukhudzika kwake kwachilengedwe komanso kutsitsa kwa lipid kumachulukitsa,
• mavitamini osungunuka mafuta - K, D, E, A - mayamwidwe awo amasokonezeka. Chifukwa chake, mavitamini ayenera kumwedwa asanagone kapena maola awiri mutatha kumwa Orsoten.
• warfarin ndi ma anticoagulants ena - mulingo wa prothrombin umachepa, INR imawonjezereka, ndipo, chifukwa, kusintha kwa magawo a hemostatic
• cyclosporine - kuchuluka kwa cyclosporin mu plasma kumachepa. Pamenepa, kuwunika pafupipafupi kuchuluka kwa cyclosporin m'magazi kumalimbikitsidwa.

Tiyeneranso kukumbukira kuti kuchepa thupi kumatha kuwongolera kagayidwe kachakudya kwa odwala matenda ashuga. Chifukwa chake, m'gulu ili la odwala, kuchepetsa mankhwalawa kwa mankhwala a hypoglycemic angafunike.

Ndemanga za kuchepetsa kunenepa

Malinga ndi ndemanga zambiri, Orsoten amachotsera mafuta 30% pachakudya, ngakhale cholesterol imasintha, amakhala m'matumbo ndipo alibe mphamvu. Zotsatira zake, kulemera kwa thupi ndi kuchuluka kwa chiuno kumachepetsedwa kwambiri (mwakuchepetsa mafuta a visceral), pomwe munthawi imodzimodzi kuchepetsa chiopsezo chokhala ndi matenda amtima komanso matenda a shuga. Mwambiri, mankhwalawa amasintha moyo wa odwala komanso kusintha moyo wawo.

Ena mwa anthu omwe adachepetsa thupi ndi mankhwala:

1. Tsopano ine ndekha ndagula phukusi laling'ono la Orsoten kungoyesa - kuti ndiwone kuti ndi motani. Mwadzidzidzi, sizingafanane, koma ndagula kale yayikulu - ndizomumvera chisoni. Chabwino, chabwino, Orsoten adabwera kwa ine, ndidzamwa.
2. Mankhwalawa ali ndi zotsatira zoyipa zambiri, ngakhale zonse zalembedwa mu malangizo, koma momwe mungadziwire ngati muli nawo kapena ayi. Amapereka malangizo olimbikitsa akuti, ngati, mumangodya zakudya zamafuta ochepa, ndiye kuti mavuto onse amachoka .... Sanandisiye. Kwa milungu iwiri ndinatenga Orsoten, ndipo ndimayesetsa kukhala pafupi ndi chimbudzi, sizimatheka kuthana ndi matenda am'mimba, komanso kupweteka kwam'mimba. Ine sindingathenso kutenga pangozi.
3. Kamodzi kokha kumwa mapiritsi azakudya. Ndipo ndi Orsoten. Nditamwa, kuyesera kwanga konse kunenepa ndi mankhwala kunatha. Tsopano zakudya zokha ndi zakudya zoyenera. Sindikufunanso kuwononga thupi.
4. Nditafika ku pharmacy ndikuwona ma tags amtengo awa azinthu zochepetsa thupi chifukwa cha maphunzirowa, ndidatsala pang'ono kupita mtedza. Chifukwa chake, mwambiri, ndidaganiza zoyambira maphunziro a Orsoten, ali ndi mtengo wotsika mtengo. Zinapezeka kuti zimathandiziradi kuchepetsa thupi, motero sindinawope kutenga maphunziro athunthu pambuyo pake, sindinong'oneza bondo kuti ndichepetse thupi ndi ma kilos asanu ndi awiri.
5. Ndidayamba ndi mayeso a orsotene - ndidali wotsimikiza kuti zidandigwira bwino komanso zimandiyeneretsa. Pazakudya, sindinadziikire malire, sindinadziikire malire. Ndipo kuchepa thupi kukubwera. Izi zikundikwanira, choncho ndipita ku pharmacy kukamaliza kwathunthu posachedwa.
6. Adatenga mankhwala mwezi! Zotsatira zake ndi kuchotsa 4800 kulemera kowonjezereka, zinthu zowonongeka, kupweteka kwam'mimba kosalekeza! Ndinaleka kudzivutitsa, koma tsopano, mwina, mavuto am'mimba mwanga ayamba, sindikufuna kudya kwambiri, nseru !! Atsikana, upangiri wanga kwa inu ndi kuteteza kukongola kwachilengedwe ndipo pakhale thanzi.
7. Osakondwa naye. Malo osungira mafuta okhazikika, zinthu zawonongeka nthawi zonse, ndipo zoyipa kwambiri, njira yolamulira siingachitike, pokhapokha mukakana mafuta. Koma izi ndizopanda pake, ndiye kuti mudzabzala kwathunthu thirakiti la m'mimba.

Kumbukirani kuti kuchepetsa thupi kuwunikira za Orsotene Slim ndi Orsotene akuwonetsa kuti zotsatira zabwino kwambiri za mankhwalawa zimawonedwa ndikuphatikiza zakudya zamagulu ochepa zama calorie. Pafupifupi malo onse ogwira ntchito ochepetsa thupi amakhala ndi zokambirana za momwe izi zimathandizira kuchepetsa thupi. Monga lamulo, zimadziwika kuti mankhwalawa amalimbikitsa zotsatira zoyipa ngati munthu samachepetsa kuchuluka kwa mafuta muzakudya.

Orsoten ndi mlingo wa 120 mg orlistat amapangidwa pansi pa dzina la malonda Orsoten. Ikupezekanso mu kapisozi kapamwamba. Amagwiritsidwa ntchito pochiza kunenepa kwambiri mwa anthu okhala ndi cholozera cha misa chokulirapo kapena chofanana ndi 30 kg.

Zofananira zina za Orsoten ndi:

• Xenalten imapezeka pansi pa dzina la malonda ili ndi mulingo wa yogwira pophika 120 mg ndipo pansi pa dzina la Xenalten Kuwala ndi mulingo wa 60 mg. Zimawonetsedwanso kuti muchepetse phindu la kubwereza thupi pambuyo pakuchepetsedwa. Yopangidwa ku Russia ndi Obolensky - kampani yopanga mankhwala,
• Alli ndi mankhwala omwe amapangidwa ndi orlistat mu mlingo wa 60 mg. Kutulutsa Nambala 21, 42 ndi 84. Wopanga: GlaxoSmithKline Consumer Helthcare LP (USA),
• Orlimax ali ndi zofanana ndi zomwe oimira am'mbuyomu a m'mimba a lipase inhibitors.Orlimax-Light imakhala ndi Mlingo (60 mg) nthawi 2 kuposa Orlimax. Amapangidwa ndi kampani ya Polpharma (Poland),
• Listata ndi Listata mini amapezeka pamapiritsi okhala ndi Mlingo wa 120 ndi 60 mg, motero. Chizindikiro chowonjezera cha Listata ndikugwiritsa ntchito kuphatikiza mankhwala opangidwa ndi hypoglycemic pochizira kunenepa kwambiri kwa odwala omwe ali ndi matenda osokoneza bongo omwe samatengera insulin. Wopanga: Izvarino Pharma LLC,
• Orlistat Canon ndi mankhwala apakhomo omwe amapangidwa mu Mlingo wa 120 mg. Wopanga: Canonfarm Production.

Chidwi: kugwiritsa ntchito ma fanizo kuyenera kuvomerezana ndi adokotala.

Mtengo wapakati wa makapisozi a ORSOTEN muma pharmacies (Moscow) ndi ma ruble 800.

Mitengo ya orsoten ku malo ogulitsa mankhwala ku Moscow

Ndemanga za madotolo za orsoten

Wodziwika bwino generic, amachepetsa kuyamwa kwamafuta. Yoyenera kugwiritsidwa ntchito pafupipafupi kwa odwala omwe amamwa kcal ochulukirapo, komanso "pakufunidwa" (mwachitsanzo, tchuthi). Ali ndi niche inayake pakusankhidwa kwake. Kukhazikitsidwa kwa machitidwe a ana ndikotheka.

Pali zotsatira zoyipa kuchokera m'matumbo am'mimba, zimachepetsa kuyamwa kwa mavitamini osungunuka a mafuta.

Idasankhidwa atakumana ndi katswiri.

Amagwiritsidwa ntchito pochiza kunenepa kwambiri komanso kunenepa kwambiri kuwonjezera pa chidziwitso chamankhwala othandizira kudya, kuchita masewera olimbitsa thupi komanso kuchita masewera olimbitsa thupi, kuphatikiza komwe kumapereka zotsatira zabwino.

Zotsatira zoyipa zilipo, sizikugwiritsidwa ntchito muubwana, ndikofunika kuchenjeza za zotsatira zoyipa zomwe zimakhudzana ndi mayamwidwe a mavitamini osungunuka.

Mankhwalawa ndi olepheretsa cham'mimba kwambiri pakamwa, m'mawu ena, chifukwa chakuti ma triglycerides samatenga, kuchuluka kwa zopatsa mphamvu zomwe zimalowa m'thupi kumachepa, ndipo munthu amachepetsa. Dziwani kuti mankhwalawa sioyenera odwala onse onenepa. Komabe, ndizofunikira kwambiri kwa odwala omwe amakonda kudya kwambiri komanso kudya zakudya zopatsa mphamvu kwambiri, makamaka pa gawo loyamba la kuchepetsa thupi, zikavuta kwambiri kuti wodwala asinthe mtundu wina wazakudya! Musaiwale kutsatira malingaliro a dokotala wanu, ndiye kuti zonse zichitike!

Zonse, mankhwala abwino.

Nthawi zambiri pamakhala zoyipa zakumaso kwa chimbudzi chotayirira (chabwino kwa anthu omwe akudwala kudzimbidwa), zikwangwani zamafuta pansalu zimadziwika, zomwe zimafuna kugwiritsidwa ntchito kowonjezereka kwa ma pads (kwa amayi, kwa amuna, mbali iyi yovuta ndizovuta), mtengo wa mankhwalawo ndiwokwera kwambiri.

"Orsoten" amachepetsa kuyamwa kwa mavitamini osungunuka a mafuta A, D, E, K. Ngati wodwalayo adya kwambiri, ndiye kuti mukamamwa mankhwalawo nthawi zambiri pamachitika zovuta zina.

Palibe mankhwala ochepetsa thupi. Orsoten samathetsa vutoli. Poyerekeza ndi momwe mankhwalawo amathandizira, mankhwalawa amatha kuchepa, pokhapokha mankhwalawo atengedwa.

Mankhwala abwino, malinga ndi malamulo ovomerezeka.

Zotsatira zotsimikizika pakuchepetsa thupi, kuphatikiza kusungidwa kwa malamulo azakudya zabwino komanso kukula kwa kayendetsedwe ka magalimoto. Zimapezeka pamtengo. Zogulitsidwa nthawi zonse, pafupifupi mu mankhwala aliwonse. Zotsatira zoyipa ndizochepa kwambiri, ngati osagwiritsa ntchito zakudya zamafuta.

Ndemanga za wodwala za orsotene

Wondipatsa zakudya adandiuza mankhwalawa. Unali mankhwala oyamba omwe amayenera kundithandiza kuchepetsa thupi. Ndidapitilira ntchito yonse ya chithandizo chamankhwala, ndipo zomwe ndikufuna kunena ndikuti mankhwalawa adandithandizadi kuti ndikhale ndikuchotsa mapaundi owonjezera omwe adandilepheretsa kuti ndikhale ndi moyo wokangalika. Ngati mukuganiza kuti ndizokwanira kugula piritsi yamatsenga ndikungokhala kuti mudikire kuwonda, ndiye kuti mwalakwitsa kwambiri, sichinsinsi kuti zotsatira zabwino ndi zotsatira zabwino zimachitika limodzi ndi zochitika zolimbitsa thupi, masewera olimbitsa thupi moyenera.

Zinali zovuta kwambiri kuti ndiyambe kumenya nkhondoyi ndi kunenepa kwambiri. Panali zoyeserera zambiri ndipo zonse zinalephera. Nthawi zina amasunga chakudyacho kwa sabata limodzi, koma kutha kwake sanawone zotsatira ndikuwaphwanya. Koma ndidapeza njira yopulumukira. Chithandizo cha ku Europe "Orsoten" chinandithandiza, nditayamba kudya ndinayamba kuzindikira kuti kulemera kunayamba kuchoka mwachangu. Malinga ndi upangiri wa dokotala, anapitiliza kumwa mankhwalawa. Mankhwala siotsika mtengo kwambiri, koma amalungamitsa mtengo wake. Ndamva kuchokera kwa abwenzi kuti sioyenera aliyense, koma ndikuganiza kuti ndikofunikira, kuyesera kuyamba kuzitenga kwa aliyense amene akufuna kukwaniritsa zotsatira zake posachedwa. Ndikulangizani!

Kuphatikizidwa ndi chidzalo, nthawi zonse kufunafuna yankho logwira, kuyesera ndipo sanadandaule! Zotsatira zake ndizododometsa: 10 makilogalamu pamwezi otsala popanda zovuta zambiri. Siotsika mtengo, koma imalungamitsa zotsatira zake. Ndakhala ndikugwiritsa ntchito kwa chaka chimodzi, ndine wokondwa kuti ndapeza mankhwalawa. Ndipo palibe zoyipa, monga kudzimbidwa kapena khungu loyipa. 100% mankhwala anga!

Kulakalaka kukhutiritsa chakudya changa bwino sikundisiya; ndimalolera kudya pang'ono pambuyo pa zisanu ndi chimodzi ndipo sikuchepetsa kuchuluka kwa chakudya konse. Popita nthawi, adayamba kuona kuti mwachionekere wawonda, anzawo akutembenukira kwa iwe, ndazindikira kuti ndiyenera kusiya. Komabe, zoletsa muzakudya sizinathandize, adakhumudwa, koma adapitilizabe kulimbana. Adapita kukaonana ndi dokotala, ndidalangizidwa ndi Orsoten, ndikulonjeza kuti kuchepetsa magawo sikufunika, ndipo zotsatira zake zimakhala zodabwitsa. Ndidayamba kumwa, patatha sabata limodzi masikelo adaonetsa kuchepa, adapitiliza kulandira chithandizo, kutsatira malangizo omwe adalembedwa, posachedwa Zizindikiro zidafikira. Tsopano ndimagwiritsa ntchito zomwe ndimakonda, ndipo sindimapeza makilogalamu.

Anatenga "Orsoten", adakonda kwambiri mankhwalawa pochizira kunenepa kwambiri komanso kunenepa kwambiri. Vuto la kunenepa kwambiri nthawi zonse, koma upangiri wa endocrinologist adaganiza zoyesa, ndipo mankhwalawo adakwaniritsidwa. Anasintha kadyedwe kake ndikumutenga Orsoten. Ndiye mpulumutsi wanga, - wataya 15 kg. Panthawi ya tchuthi, mumatenga piritsi limodzi ndikuyiwalako za mapaundi owonjezera. Mankhwalawa ndi bomba ndipo, koposa zonse, amakhala otetezeka, chifukwa samatengedwa m'magazi.

Orsoten, wathunthu ndi kalabu yolimbitsa thupi, adandiuza kuti azindipanga ndi endocrinologist. Ndili ndi matenda a shuga a 2 + onenepa kwambiri. Pansi pamzere: kusakhazikika kunali koyambirira, komanso m'masiku ogwiririra ntchito zakudya zamafuta. Kuyambira pa Julayi 2018 mpaka pano, ma kilogalamu 18 adatsitsidwa, ngakhale kuti adakwanitsa kupita ku masewera olimbitsa thupi ndikuyamba kupitanso kawiri pa sabata. Chifukwa chake, ngati mankhwalawo ndi oyenera kwa inu, ndiye kuti pali zovuta kuchokera pamenepo.

Adatenga "Orsoten" miyezi iwiri ali ndi chiyembekezo chosazindikira kuti iyi ndi "piritsi yamatsenga" yakuchepetsa. Nthawi yomweyo, ndinayesetsa kutsatira zakudya, chifukwa Zotsatira zoyipa zimaphatikizira ziwalo zotayirira, kupweteka kwam'mimba ndi mkuntho, komanso kutulutsa mafuta kosalamulirika. Kuphatikiza pazotsatira zoyipa, ngakhale pazakudya zamafuta ochepa, sizinachitike. -1kg kwa miyezi iwiri sizotsatira (ndiye kuti kulemera kwake kunali makilogalamu 97, zaka 32). Patatha mwezi umodzi wambiri atatha kudya, kulemera kunakula ndi 3 makilogalamu ndikudya kosalekeza. Sindikupangira kuti mutenge nokha, popanda kupereka mankhwala ndikuwunika dokotala, ndibwino kungodya molondola. Mtengo wa maphunzirowa ndi wokwera (imwani miyezi 2-3 kumvetsetsa ngati pali zotulukapo).

Ndemanga zanga mwina zikuwoneka ngati zotamandika kwambiri kwa inu, koma ndimakondwera ndi mankhwalawa. Ndinayamba kutenga Orsoten nditabadwa mwana wanga wachiwiri. Molondola, chaka chotsatira, pamene ine ndinali nditasiya kale kuyamwitsa. Sindikudziwa ngati nkotheka kumwa mankhwalawa ngati mkaka wina, koma sindinatenge ziwopsezo, ndipo ndinangoyamba kumwa pokhapokha ndasiya mwana kuyamwa. Mankhwala ndi othandizadi. Ndidathandizidwa kuti ndizikhala bwino sabata limodzi, kunalibe mafuta ambiri. Ena adanena kuti mankhwalawa amatha kukhala ndi mavuto, koma sindinawone konse, kuchepa thupi kunalibe mavuto komanso kuvulaza thanzi.

Atandichita opareshoni, ndinayamba kulemera msanga, ndipo nthawi yomweyo ndinapita kwa dotolo ndi vutoli. Anandipatsa miyezi isanu ndi umodzi yakuchepa kwa thupi pa Orsotene mafuta blocker. Popeza kale ndinali wocheperako, miyezi isanu ndi umodzi inkawoneka kwa ine motalika, koma ndinadzozedwa nditawona zotsatira. Zotsatira zake, 13 makilogalamu adapita panthawiyi osadya, chilichonse monga adanena.

Kunenepa kwambiri ndi banja lathu, ndipo ngati pali zovuta zomwe zingachitike, ndizovuta kwambiri kuthana nazo. Ndimapulumutsidwa ndi Ortosen, ndimamwa nthawi ndi nthawi mpaka ndidzafika polemera - 65 kg.

Nthawi zonse ndimagula phukusi laling'ono la Orsoten kwa sabata limodzi ku tchuthi, kuti asandipe. Ma buffet pa tchuthi ndi zikondwerero zapanyumba ndizopamwamba kwambiri zopatsa mphamvu, koma Orsoten amandipulumutsa ku mafuta ochulukirapo. Amangoziletsa. Zaka zingapo zapitazo, ndinakhala pachaka kwa chaka chathunthu.

Ndidayenera kukhala bwino nditabadwa mwana, koma kodi mupezadi nthawi yamasewera ndi mwana wanu? Popanda kupsinjika mosafunikira pa "Orsoten" adatenga 8 kg m'miyezi isanu. Wina anganene kwa nthawi yayitali, koma kubweza pang'ono pang'onopang'ono kunenepa ndikubweza thupi. Miyezi yowerengeka iyi inali yokwanira kuti ndiyesetse kagayidwe, ine ndinangozolowera kudya bwino.

O, atsikana, musayese Reduxine. Uwu ndi mtundu wina woopsa, osati wowachiritsa. Ndinamupsera nkhawa kwambiri mpaka ndinamuopa kwambiri. Ndatsala pang'ono kugona, sindikufuna chilichonse. Kenako analavulira, kusiya kumwa, adotolo adandisamutsira ku Orsoten. Nkhani yosiyanatu! Kusunthika kumakhala kosalala, monga nthawi zonse, kulemera kumatsikiranso pang'onopang'ono. Mwambiri, ndimalangiza aliyense.

Ndinayesanso kumwa Xenical nthawi imodzi, ndiwokondedwa. Chabwino, ndimaganiza kuti mtengo udzakhala wolungamitsidwa ndi mtundu, koma ayi. Kuchokera kwa iye ndinali wofooka kwambiri. Wopatsa zakudya adandiwuza kuti ndilandire Orsoten, ndipo adandithandizira kuonda kwambiri. Popanda zotsatila zilizonse.

Otsatira a HLS akuti masewera okha amathandizira kuchepetsa thupi, koma siine anga. Kupita ku masewera olimbitsa thupi, thukuta pamadzi opanga ma simulators pamtunda ... chabwino, zosatheka! Ndiosavuta kwa ine. Ndinkadzisankhira Orsotin Slim. Iwo adamulangiza pa pharmacy. Ndakhala m'mwezi wachiwiri, mayendedwe akadali ocheperako, 3 makilogalamu, koma ali!

Panthawi yolandila "Orsoten" zidapezeka kuti ndisanamvetsetse kuti ndi mafuta angati omwe amapezeka. Ndinayenera kukonza, ndipo sindinadandaule. Makilogalamu 11 otayidwa sanabwerere. Kupatula apo, ndinakhetsa thupi kuchokera ku zopatsa mphamvu zochuluka. Ndimathokoza dokotala wanga komanso wopanga "Orsoten": mankhwalawa abwino, othandiza komanso otsika mtengo kuposa ma analogues: "Xenical" ndi "Listy".

Mosiyana ndi mankhwala omwe amagwira ntchito pa psyche, Orsoten amangogwira mayamwidwe amafuta - amawalepheretsa. Sindinayese Reduxine konse, zinayambitsa kupsinjika kwa bwenzi langa, ndipo kulemera kwake sikunachepe. "Orsoten" adandisankhira chifukwa sindingathe kudya kwambiri - thupi ndiloleza. 1.5 - 2 kg pamwezi amandisiya pa "Orsotnene", ndikupitiliza kumwa.

Zomwe sindinayesere kuchepera thupi! Ndipo zolimbitsa thupi ndizokhazikika (panali kumangomva kutopa kuchokera kwa iwo), ndipo zakudya ndizosiyana (ndizabwino kuti sindinakhale ndi m'mimba), ndi dziwe (ichi ndi chinthu chabwino, ngakhale sindikuchepetsa thupi chifukwa chosambira). "Orsoten" anathandizira kuchotsa pansi, tsopano ndi 2 kg. Zotsatira zake ndi zolimbikitsa, palibe mavuto omwe adawonedwa.

Ndakhala ndikumwa mankhwalawa kwakanthawi. Kusintha kwa kuwonda kumawonekera. Nthawi zambiri panali zotsatira zoyipa kuphwanya m'mimba. Kulakalaka kudachepa. Woyang'anira wanga adati Orsoten amachepetsa kuyamwa kwa mavitamini, omwe ndi abwino. Kwa miyezi iwiri ya zakudya zoyenera, ndikuphatikiza ndi Orsoten, ndataya 7 kg., Zomwe ndimawona kuti ndizabwino kwambiri. Kwa anthu omwe akutsatira chithunzichi, mankhwalawa ndi oyenera kumwa ndikudya zakudya zamafuta.

Nthawi zambiri ndimayang'anira kuwonda kwanga komanso zakudya. Koma munthawi yovuta imodzi, kwa ine kunenepa kwambiri. Sindinathe kudzipangitsa kuti ndichepe thupi, motero ndinasankha kugwiritsa ntchito mapiritsi kuti ndikadzilimbitsa. Wogulitsa mankhwalawa adalimbikitsa mankhwalawa kwa ine. Koma, monga momwe zidakhalira pambuyo pake, pakuchepetsa thupi, sizigwira ntchito konse ayi, koma zingathandize kuti musamachulukenso. Muyenera kumwa mapiritsi awa mukamadya mafuta, ndiye kuti amachotsa bwino mafuta mwanjira, zomwe zimathandiza kuti mafuta awa asamayikidwe kumbali ndi m'mimba. Koma mafuta omwe ali kale m'malo awa a thupi, sapita kulikonse. Mukamadya zakudya zamafuta ochepa, simuyenera kumwa. Kulakalaka sikuchepetsedwa konse. Ndidakhala sabata zitatu, zotsatira zake ndi ziro. Tsopano watha kale kulemera, ayambanso kudya, ndimamwa mapiritsiwa ndikamadya kena kenakake mafuta nthawi ya tchuthi, kuti asalemere.

Mankhwala abwino kwambiri ochepetsa thupi, ndipo madokotala amavomereza, ndikulimbana ndi mapaundi owonjezera, ndinatsimikizika kuchokera pazomwe ndinakumana nazo. Satha kuthana ndi kunenepa kwambiri, "Orsoten" adatha kupirira bwino ntchitoyi. Ndimakondwera ndi zotsatirazi.

Nditatenga, ndidawona kusintha kosiyanasiyana pamavolumu ndi zovala, ndipo kunayamba kuonekera, pomwe ndimamwa theka, ndimamwa mapiritsi 42. Ndikuganiza zotsatira zake zingandisangalatse. Nthawi yomweyo ndimayesetsa kuchita Cardio tsiku lililonse, ngati zingatheke, ndipo ndikudziika ochepa maswiti. Pakadali pano, ndikufuna kunena kuti mankhwalawa amagwiradi ntchito. Manambala onse abwino pamiyeso!

Dotolo adandiuza kuti mpaka pano ndi njira zokhazokha za ku Europe zomwe zitha kudalirika, kotero chifukwa chochepetsa thupi European Orsoten idandilangiza. Koma zotsatira zake ndi zabwino, osachotsa kale zisanu. Chifukwa chake ndili wokondwa.

Ndimamwa Orsoten. Madokotala amavomereza chida cha European - kotero mutha kuchepa thupi popanda kuwopa kubzala chiwindi kapena kuwononga m'mimba mwanu. Ndipo kulemera, njira, kumachokeradi!

Orsoten adayesera izi patchuthi cha Chaka Chatsopano, mlongo wake adanyamula. Kenako anandipulumutsa mwachindunji! Tsopano ndikuganiza z kumwa maphunziro, motero ndinatenga ma CD anga kuti ndikayesere maphunziro.

Anasiyidwa osagwira ntchito ndipo popeza kukhala kunyumba nthawi zonse kumapeza ndalama zochulukirapo. Ndinaganiza zochepetsa thupi, koma zakudya sizinathandize. Ndinawerenga za Orsoten pa intaneti, ndimaganiza kuti ndi mapiritsi amatsenga, koma tsoka, mankhwalawa sanandithandizire. Ndinkamwa zonsezo monga momwe zidalembedwera m'malangizo, ndinapenda zakudya zanga ndikulowa m'masewera kwambiri, koma kulemera kwake kunali kutatsala pang'ono kutha, kudali 96, ndipo kudakwaniritsidwa kukhala 94 patatha mwezi, koma izi sizotsatira zomwe ndimayembekezera. Sindinakhale ndi zotsatirapo zoyipa kuchokera pamaphukusi awa, koma sizinakhalepo ndi zotsatirapo zabwino.

Ndidawerama nyambo iyi pofuna kufunafuna wowoneka bwino komanso wokongola. Popeza sinditsatira zakudya ndipo ndimakonda kudya chakudya chokoma ndi chopatsa thanzi, ndidaganiza kuti njira yochepetsera thupi yandiyenera bwino. Ndidawerenga kale za mankhwalawa, ndidazindikira kuti ndemanga ndizosiyana: pali zabwino, komanso zambiri zoyipa. Zotsika mtengo zidagwira ntchito, ndidaganiza zokhala nawo mwayi. Ndinawona makapisozi momveka bwino, monga momwe analimbikitsira, koma palibe chapadera chomwe chinachitika. Zovala zowumitsa zimawonekera ndipo nthawi zina m'mimba zimapweteka. Kulakalaka monga momwe kunaliri ndikutsalira, ngakhale ndimayesetsa kudya zochepa kuposa masiku onse. Khalani ndi ine komanso kunenepa kwambiri.

Ndinagula mankhwalawa ndili ndi chiyembekezo chodya ndi kunenepa. Mtengo wake ndi wokwera mtengo pang'ono - umatenga pafupifupi ma ruble 3,000, mankhwalawa amatenga kapisozi imodzi katatu patsiku. Sanandiyenerere, mwina chifukwa ndikuti kulemera kwanga sikunali kwambiri - 67 kg. Angabzalidwe chiwindi "chabwino", sindikukulimbikitsani kumwa mankhwalawa!

Kulemera kwambiri kwa ine ndi vuto lalikulu ndi thanzi komanso moyo wamunthu. Chilichonse chatsika, sindinkafuna kukhala ndi moyo. Ndili ndi matenda ashuga, chifukwa chake bwino, amangokula m'lifupi. Ndidayesera mitundu yonse ya zakudya, ndipo matenda anga anali ochepa aiwo, ndipo palibe omwe adabweretsa phindu lililonse. Mankhwala ochepetsa thupi amalemekezedwa kwambiri, palibe chomwe chinatsalira kupatula mafuta. Ndipo mphindi zomaliza, endocrinologist adandilangiza Orsoten.Mwezi womwewo ndinataya 2 kg, osati zochuluka, koma palibe malire a chisangalalo, ndipo ndikupitilizabe kuchepa koma moyenera kuchepetsa thupi. Munthu akhoza kunena kuti sindimawona zotsatira zoyipa zilizonse.

Kufotokozera kwapfupi

Orsoten (yogwira pophika - orlistat) ndi mankhwala wochizira kunenepa kwambiri. Masiku ano, kufalikira kwa kunenepa kumapereka chifukwa chokwanira kudziwa ngati si mliri, ndiye vuto lalikulu kwambiri lachipatala chamakono. Chifukwa chake, malinga ndi Global Database of Body Mass Index yolembedwa patsamba la WHO, onenepa kwambiri m'maiko otukuka amakhudzidwa ndi 23% (Japan) mpaka 67% (USA). Mafuta ochulukirapo a thupi amathandizira kutenga matenda a mtima ndi shuga, zomwe ndi zina mwazomwe zimayambitsa kufa. Popeza pamwambapa, chithandizo chokwanira cha kunenepa kwambiri nthawi zonse chiyenera kukhala chowunikira oyang'anira mtima, ma endocrinologists ndi madokotala a akatswiri ena. Zochita zomwe cholinga chake ndikuchotsa mafuta osungira a visceral, zimakhudza ambiri pazovuta za metabolic zomwe zimakhudzana ndi kunenepa kwambiri. Ngakhale kuchepa pang'ono kwa 5-10% kumayendetsedwa ndi kuchepa kowonekeratu kwa zochitika zamtundu wa concomitant. Poganizira kuti zomwe zimayambitsa kunenepa kwambiri ndizochita zolimbitsa thupi molumikizana ndi kusachita masewera olimbitsa thupi, chithandizo chiyenera kukhazikitsidwa pakumanga chakudya ndi mafuta "katundu" osaposa 25-30% ya okwanira tsiku ndi tsiku a calorie osakanikirana ndi masewera olimbitsa thupi omwe amachitika mu mawonekedwe a aerobic. Kuonjezera phindu la mankhwalawa, "othandizira" a pharmacological amagwiritsidwa ntchito, omwe amadziwika kuti Orsoten. Ndi cholepheretsa champhamvu cham'mimba komanso ma pancreatic lipases a nthawi yayitali, kupondereza kufalikira kwa lipid ndi mayamwidwe pafupifupi 30%. Nthawi yomweyo, orsotene amachepetsa kuchuluka kwamafuta acids ndi monoglycerides mu lumen yam'mimba, yomwe imaphatikizira kuwonongeka kwa solubility ndi mayamwidwe a cholesterol komanso kuchepa kwa kuchuluka kwake m'madzi a m'magazi. Chimodzi mwazinthu zabwino za orsotene ndi kusankha kwakanema kwa ma enzymes m'mimba ndikutsiriza "kusaloledwa" pokhudzana ndi mapuloteni, chakudya ndi phospholipids.

Mankhwalawa amangogwira ntchito m'matumbo, popanda njira iliyonse. Zotsatira za kafukufuku wazachipatala zambiri zimangowonetsa mphamvu yake yochepetsera kulemera kwamthupi, komanso kubwezeretsanso kuchuluka kwa ma lipids am'magazi pazikhalidwe zathupi. Zinawonetsedwa kuti kugwiritsa ntchito orsoten kwa miyezi 12 molumikizana ndi kukonza kwa njira (kuchotsedwa kwa zolakwika zamthupi, zolimbitsa thupi) kunapangitsa kutsika kwa thupi ndi 5% kapena kupitilira mu 35-65% ya odwala ndi 10% kapena kuposa mu 29- 39% ya odwala. Mankhwala a Orsoten ochokera ku kampani yopanga mankhwala ku Slovenia "Krka" ndiwofotokozedwawu wochokera ku ("F. Hoffman La Roche Ltd." (Switzerland)) Asayansi aku Russia ochokera ku Federal State Institution "Endocrinological Research Center" (Moscow) anayerekeza kugwira bwino ntchito pokhudzana ndi kuchepetsa thupi xenical and orsoten: Zotsatira za phunziroli zinawonetsa kufanana kwa mankhwalawa onse, mphamvu yawo yofanana mwa odwala onenepa, ndikufanana kwa mbiri yawo yachitetezo. Phunziroli, chithandizo cha orsotene chinalola anthu ambiri (pafupifupi 52%) odwala onenepa kuti achepetse kuchepa kwa thupi kuposa 5% pambuyo pa miyezi 3 ya pharmacotherapy. Kutaya mafuta owonjezera thupi panthawi yamankhwala a orsotene kunakhudza kwambiri chiopsezo cha Cardio - matenda am'mimba ndi matenda ashuga komanso kukonza moyo wa odwala.

Orsoten amapezeka m'mapiritsi. Malinga ndi malingaliro ambiri, mlingo umodzi wa mankhwalawo ndi 120 mg. Orsoten amatengedwa asanadye (kutanthauza chakudya cholimba, osati zopepuka), mkati mwa ola limodzi kapena itatha. Kaphimbidwe kamatsukidwa ndi madzi okwanira. Ngati mukufuna kudya "wopanda" chakudya, ndiye kuti mutha kudumpha kapena kudya zakudya zamagulu ena. Mlingo wa mankhwala opitirira 120 mg katatu patsiku sizikuthandiza.

Pharmacology

Inhibitor yeniyeni ya lipases yam'mimba yokhala ndi mphamvu yayitali. Imakhala ndi achire mu lumen yam'mimba ndi matumbo ang'onoang'ono, ndikupanga mgwirizano wolumikizana ndi gawo loyambira la gawo la m'mimba ndi matumbo lipases. Mosakhazikika mwanjira iyi, enzyme imataya mphamvu yake yophwanya mafuta azakudya mu mawonekedwe a triglycerides kulowa mu mafuta aulere acids ndi monoglycerides. Popeza ma triglycerides osaphatikizidwa samayamwa, kuchuluka kwa zopatsa mphamvu m'thupi kumachepa, zomwe zimapangitsa kuchepa kwa thupi.

Achire zotsatira za mankhwala ikuchitika popanda mayamwidwe zokhudza zonse kufalitsidwa. Kuchita kwa orlistat kumabweretsa kuwonjezeka kwa mafuta omwe amapezeka mumayimbidwe omwe ali kale maola 24-48 mutamwa mankhwalawa. Pambuyo pakutha kwa mankhwalawa, mafuta omwe amakhala mumadzimadzi nthawi zambiri amabwerera ku mawonekedwe ake atatha maola 48-72.

Pharmacokinetics

Kuyamwa kwa orlistat ndizochepa. Maola 8 mutatha kumwa mankhwalawa, mankhwala osasinthika am'madzi am'magazi samatsimikizika osagwirizana ndi ndende ya 5 ng / ml. Palibe zizindikiro zakumvera, zomwe zimatsimikizira kuyamwa pang'ono kwa mankhwalawo.

Mu vitro, orlistat ndizoposa 99% zomanga ndi mapuloteni a plasma (makamaka lipoproteins ndi albin). Pochulukirapo, orlistat imatha kulowa m'magazi ofiira.

Orlistat imapukusidwa makamaka khoma lamatumbo ndikupanga ma metabolacogic metabolites: M1 (hydrolyzed anayi lactone ring) ndi M3 (M1 yokhala ndi zotsalira za N-formylleucine).

Njira yayikulu yotsatsira ndikuchotsa matumbo - pafupifupi 97% ya mankhwala, omwe 83% - osasinthika.

Cumulative excretion wa impso wazinthu zonse zomwe zimapangidwa ndi orlistat, ndizochepera 2% ya mlingo wa mankhwalawa. Nthawi yochotsa kwathunthu ndi masiku 3-5. Orlistat ndi metabolites atha kupukusidwa ndi bile.

Kutulutsa Fomu

Makapisozi kuyambira oyera mpaka oyera okhala ndi chikasu chachikasu, zomwe zili m'mabotolo ndi ma Micronanules kapena osakaniza a ufa ndi ma micogranules a mtundu oyera kapena pafupifupi oyera, kupezeka kwa ma babu ophatikizidwa, osweka mosavuta akakakamizidwa.

* 100 g ya gramules yomaliza yokhala ndi: orlistat - 53.1915 g, cellcrystalline cellulose.

Omwe amathandizira: cellcrystalline cellulose.

Zomwe zimapangidwira thupi ndi kapisozi kapisozi: hypromellose, madzi, titanium dioxide (E171).

7 ma PC - matumba otumphukira (3) - mapaketi a makatoni.
7 ma PC - matumba a matuza (6) - mapaketi a makatoni.
7 ma PC - matumba otumphuka (12) - mapaketi a makatoni.
21 ma PC. - matumba otumphuka (1) - mapaketi a makatoni.
21 ma PC. - mapepala otumphukira (2) - mapaketi a makatoni.
21 ma PC. - mapaketi a matuza (4) - mapaketi a makatoni.

Mlingo umodzi wovomerezeka ndi 1 chipewa. (120 mg).

Kaphidwe kamtsuko kamatsukidwa ndi madzi, kumamwa pakumwa nthawi yomweyo musanadye chakudya chachikulu chilichonse, mukamadya kapena osaposa ola limodzi mutatha kudya. Ngati chakudya chidatsitsidwa kapena ngati chakudya mulibe mafuta, mutha kudumpha orlistat.

Mlingo wa orlistat woposa 120 mg katatu / tsiku samapititsa patsogolo njira zake zochizira. Kutalika kwa mankhwala sikupitilira 2 years.

Kusintha kwa Mlingo sikofunikira kwa okalamba kapena odwala omwe ali ndi vuto la chiwindi kapena impso.

Chitetezo ndikuyenda bwino kwa orlistat pochizira ana ndi achinyamata ochepera zaka 18 sizinakhazikitsidwe.

Mimba komanso kuyamwa

Malinga ndi zotsatira za kafukufuku wamakedzana, teratogenicity ndi embryotoxicity sizinawoneke mukamamwa orlistat. Palibe zambiri zakuchipatala pakugwiritsa ntchito orlistat pa nthawi yomwe muli ndi pakati, motero mankhwalawa sayenera kufotokozedwa panthawiyi.

Chifukwa Zomwe zimagwiritsidwa ntchito pa nthawi ya mkaka wa mkaka, orlistat sayenera kutumikiridwa panthawi ya msambo.