Mildronate - malangizo ogwiritsira ntchito, omwe mapiritsi ndi jekeseni amalembera, mtengo, ndemanga, analogues

MILDRONAT ® (Mildronate ®) - mawonekedwe ndi malangizo ogwiritsira ntchito, mtengo wotsika, kuyika zithunzi, zithunzi za mankhwala, mavuto ndi zotsutsana. MILDRONATE ® (mapiritsi, jakisoni, makapisozi) ndi mankhwala a metabolic omwe ndi analogue yopanga ya gamma-butyrobetaine, chinthu chomwe chimapezeka mu khungu lililonse la munthu. Musanagwiritse ntchito mankhwalawa, ndizomveka kudziwa kuti Mildronate adalembedwa chifukwa chiyani. Chidwi chachikulu pakati pa anthu wamba chimachitika chifukwa cha malangizo a madotolo oti "Mildronat", ndemanga zakugwiritsa ntchito mankhwalawa.

Mildronate (meldonium, cardionate) - mankhwala omwe amapangitsa kuti kagayidwe kazikhala ndi mphamvu komanso zopatsa mphamvu, kamapezeka pa mankhwala. Mankhwalawa adapangidwa mu 70s ya XX century ku Institute of Organic Synthesis of the Latvian SSR, yopangidwa ndi Pulofesa Ivar Kalvins. Pakatikati pake pankakhala patent ngati njira yolamulira kukula kwa mbewu ndikuthandizira kukula kwa nyama ndi nkhuku.

WADA imamuwona Mildronate ngati wopanga wa metabolism ofanana ndi insulin. Kafukufuku yemwe adasindikizidwa mu Disembala 2015 mu magazini yotchedwa Drug Testing and Analysis, akuti meldonium imachita bwino masewera othamanga, mphamvu, imabwezeretsa kuchira, imateteza ku kupsinjika ndikuwonjezera ntchito yanthawi yayitali yamanjenje.

Kuyambira pa Januware 1, 2016, meldonium idawonjezeredwa ku gulu la S4 (Hormones and metabolism modulators) mndandanda woletsedwa ndipo amaletsedwa kugwiritsa ntchito munthawi yopikisana komanso yopanda mpikisano. Chidachi chidafalitsidwa ponseponse chifukwa chamilandu yambiri yamasewera, monga momwe amafananizidwa ndikutulutsa. Komabe, ngati kugwiritsa ntchito kwake pamasewera kumakhala kochepa, ndiye kuti anthu wamba amatha kugwiritsa ntchito chida ichi, komabe, ndikokhazikitsidwa ndi dokotala.

Mildronate - malangizo ogwiritsira ntchito omwe amafotokozera ndi zisonyezo ndi mulingo, amapangidwa ndi wopanga m'njira zitatu: kapisozi ya gelatin, ma ampoules pokonzekera jakisoni wosungunuka m'madzi, mapiritsi.

Ili ndi zotsatirapo zosiyanasiyana za mankhwala: antianginal (yolunjika motsutsana ndi ziwopsezo za angina), mtima, antihypoxic (kuchuluka kwa kukana kugona ndi mpweya) ndi angioprotective (opindulitsa khoma lamitsempha ndi ma cellcirculation).

Kuchita kwake kunatsimikiziridwa ndi malamulo onse a zamankhwala zokhazikitsidwa ndi umboni m'mayeso awiri akhungu, osasankhidwa mwachisawawa omwe amachitika ku Riga ndi Tomsk. Inde, ndipo sizokayikitsa kuti Mildronate akadakhala wotchuka pakati pa akatswiri apakhomo, odwala, ngakhale othamanga, ngati anali "dummy" wopanda ntchito.

Chifukwa chani ndipo akufunika a Mildronate-meldonium: lipoti

Mwa osagwiritsa ntchito ntchito, pali chikhulupiriro cholakwika chakuti kugwiritsa ntchito Mildronate kumatha kukulitsa kuchuluka kwa minofu. Malingaliro ndi olakwika kwathunthu, mankhwalawa alibe mphamvu pa minofu yambiri. Ochita masewera amatenga Mildronate kokha ngati njira yobwezeretsanso nyonga, kulimbitsa thupi ndikukulitsa kukana kupsinjika.

Koma mawu oti Mildronate amathandizira minofu kusinthika ndi yolondola. Inde, mukamwa mankhwalawa, maselo amachira msanga, momwe mpweya wabwino umafalikira. Metabolism imakhalanso yogwira ntchito. Ogulitsa, Mildronate amapezeka mu ma ampoules, mapiritsi ndi makapisozi. Ampoules amakhala ndi madzi apadera omwe ali okonzeka kugwiritsa ntchito.

Poyerekeza ndi kuchuluka kwa kuchuluka, mankhwalawa amagwiritsa ntchito momwe mpweya umaperekera kwa maselo ndikumwedwa komwe akupita, umalepheretsa kuchuluka kwa zinthu zopangidwa ndi poizoni m'maselo, kuziteteza kuti zisawonongeke, zimakhala ndi mphamvu komanso kupatsa chidwi - malangizo ogwiritsira ntchito amatsimikizira izi.

Chifukwa cha Mildronate, thupi limapatsidwa mphamvu yokhoza kupilira katundu woonjezereka komanso mwachangu kubwezeretsa mphamvu zake. Pankhaniyi, ntchito yofewa imagwiritsidwa ntchito pochiza matenda osiyanasiyana a mtima, kuchepa kwa mitsempha, kumawonjezera kugwira ntchito kwamthupi ndi thupi.

Mphamvu za vasodilating za mildronate zimatheka chifukwa chakuchepetsa kuchepa kwa carnitine ukukulitsa kaphatikizidwe ka gamma-butyrobetaine.

Pakulephera kwa mtima, kufewetsa thupi kumathandiza kuti myocardium ikhale bwino ndikulolera zochitika zolimbitsa thupi,
Mu ophthalmology, mildronate imagwiritsidwa ntchito ngati mtima ndi dystrophic fundus pathology,
Mu ischemia yovuta yamtima, mankhwalawa amachepetsa kuchepa kwa mphamvu ya myocyte, imathandizira kukonzanso,
Mu ischemia yovuta komanso yopanda matenda, mankhwalawa amasintha kufalitsa kwa ubongo ndikuthandizira ma cellcirculation m'malo mwa minofu yomwe imakhudzidwa kwambiri ndi ischemia.

Chifukwa cha kuthekera kwake kuthetseratu magwiridwe antchito am'magazi am'magazi mwa anthu omwe ali ndi chidakwa, mankhwalawa amagwira bwino ntchito pakuwonetsa zina. Mankhwalawa amaphatikizidwa modabwitsa ndi mankhwala awa:

Diuretics (Diacarb, Veroshpiron),
Bronchodilators (Berotek, Ventolin),
Ma antiplatelet othandizira (Aspirin Cardio, Prostacyclin),
Mankhwala a antiarrhythmic (Ritalmex, Difenin, Cordaron),
Mankhwala a antianginal (Riboxin, Sustak, Trendal).

Nthawi zina, Mildronate - malangizo ogwiritsira ntchito amalimbikitsa mphamvu ya mankhwala ena. Izi zimawonedwa pomwa mankhwalawa ndi mankhwala otsatirawa:

Cardiac glycosides (Digoxin, Strofantin),
Beta-adrenergic blockers (Metaprolol, Atenolol, Propranolol),
Mankhwala omwe amachepetsa kuthamanga kwa magazi.

Kutulutsa mawonekedwe ndi kapangidwe kake

Zogwira pophika: Meldonium (Meldonium),
Nambala ya ATX: C01EV,
Wopanga: JSC "Grindeks", Latvia,
Dzina lachi Latin: Mildronate.

Mmodzi wina wolimba wa Matinronate wolimba wa gelatin muli 250 kapena 500 mg. Meldonium mu mawonekedwe a dihydrate monga othandizira ndi othandizira: Amylum solani (wowuma wa mbatata), Silicii dioxydum colloidale (colloidal silicon dioxide), Calcium stearate (calcium stearate). Popanga chipolopolo cha gelatin, Gelatin (gelatin) ndi Titanium dioxyde (titanium dioxide) amagwiritsidwa ntchito.

Mu 1 ml. Mildronate Injection ili ndi 100 mg. Meldonium ndi madzi a jakisoni monga gawo lothandizira. Piritsi 1 ili ndi 500 mg ya Mildronate. Meldonium mu mawonekedwe a phosphate ndi othandizira: Mannitum (E421, mannitol), Povidonum K-29/32 (povidone K-29/32), Amylum solani (wowuma wa mbatata), Silicii dioxydum (silicon dioxide), Cellulose microcristalline (microcrystalline) , Magnesium stearate (magnesium stearate).

Mankhwala a Mildronate amapangidwa ndi omwe amapanga mawonekedwe a:

Mapiritsi Mildronate Gx 500 mg. (kukoma kwa piritsi ndi wowawasa pang'ono)
Jakisoni wowoneka bwino wopanda khungu
Makapisozi olimba a gelatin No. 1 ndi Na. 2, odzazidwa ndi ufa wa hygroscopic crystalline wa mtundu woyera. Mafuta omwe amapezeka m'mabotolo amakhala ndi fungo labwino komanso kakomedwe kake (kapisozi kameneka kamakhala ndi vuto losalowerera).

Makapisozi amawaunjikira matuza a zidutswa 10 chilichonse. Paketi imodzi yamakatoni muli matuza 4 ndi malangizo ogwiritsira ntchito mankhwalawa. Njira yothetsera vutoli ikugulitsidwa mu ma ampoules a 5 ml. (500 mg / 5 ml). Phukusi limodzi la makatoni limakhala ndi: 2 cell cell okhala ndi ma ampoules 5 a Mildronate chilichonse ndi malangizo ogwiritsira ntchito mankhwalawa.

Mildronate - malangizo ogwiritsira ntchito

Mukamasankha "Mildronate" mwanjira ya mapiritsi, muyenera kukumbukira: chipangizocho chimameza chonse, sichitha kutafunidwa. Zomwezo zimapita kwa makapisozi. Mapiritsi amayenera kusungidwa mumayendedwe oyambirira m'malo amdima, kutali ndi ana. Nthawi zambiri makapisozi, mapiritsi amakulimbikitsidwa kuti amwe ngati Mildronate adalembedwa kuti ndi gawo la zovuta kuchiritsa motsutsana ndi mtima.

Nthawi zambiri pamakhala mafunso “Ndikotheka kubaya Mildronate intramuscularly"Kapena"Momwe mungabayitsire mankhwala intramuscularly". Malangizo ogwiritsira ntchito kuchipatala akuwonetsa kuti kukonzekera kwa jakisoni kumapangidwira kukonzekera kwa mtsempha wa magazi, kuyenera kuperekedwa mosagwirizana ndi mankhwala ena, kuchepetsedwa ndi yankho lamadzimadzi a sodium chloride sikufunika (komabe, nthawi zina kumaloledwa), ndipo makapisozi ndi mapiritsi amayenera kuchitidwa pakamwa. (pa os).

Wopanga amalimbikitsa kuti asatenge 1 g ya Mildronate patsiku. Nthawi zambiri, Mildronate amagwiritsidwa ntchito kawiri pa tsiku. Kutalika kwa maphunzirowa ndi masiku 30, koma nthawi yina imafunikira. Akabayidwa mu minofu, yankho la jakisoni limakwiyitsa ndipo limatha kupweteketsa zakumbuyo komanso zimayambitsa mavuto am'deralo. Pachifukwa ichi, Mankhwala a Mildronate nthawi zambiri amalowetsedwa m'mitsempha.

Mlingo ndi njira yogwiritsira ntchito Mildronate zimatengera matendawa:

Ochita masewera amalimbikitsidwa kugwiritsa ntchito 500 mg-1 g 2 nthawi / tsiku musanaphunzire. Kutalika kwa maphunziro mu kukonzekera nthawi ndi masiku 14-21, pa mpikisano - masiku 10 mpaka 14,
Ndi ntchito yochepetsedwa, kupsinjika kwa malingaliro ndi thupi (kuphatikiza pakati pa osewera), 500 mg imayikidwa mkati. 2 nthawi / tsiku Njira ya mankhwala ndi masiku 10-14. Ngati ndi kotheka, mankhwalawa amabwerezedwa patatha milungu iwiri,
Pa matenda osakhazikika kwa mitsempha yamatsenga amatenga mapiritsi awiri a Mildronate (500 mg tsiku lililonse) kwa milungu inayi kapena isanu ndi umodzi. Nthawi zina, adokotala amalimbikitsa maphunziro ena, koma mchaka - osapitilira atatu,
Pazovuta zomwe zimayamba chifukwa cha uchidakwa, nthawi zambiri mumatenga 4 pa tsiku, piritsi limodzi la Mildronate (500 mg.) Kwa masiku 10,
Mu gawo la pachimake, vuto la cerebrovascular, Mildronate amathandizira masiku 10 pa 500 mg malinga ndi malangizo. kamodzi patsiku. Pambuyo pake, mutha kusintha kuti mutenge mapiritsi a Mildronate, 0,5-1 g patsiku. Njira yonse yogwiritsira ntchito mpaka milungu 6,
Pambuyo pa vuto la mtima, 500-1000 mg imayendetsedwa kudzera tsiku loyamba. yankho. Kenako wodwalayo amasamutsidwa pamapiritsi. Amayenera kumwa kawiri pa tsiku kwa 250 mg. Kenako muyenera kumwa mankhwalawa katatu patsiku (mlingo ndi womwewo), koma izi zikuyenera kuchitika kawiri pa sabata. Kutalika kwa mankhwalawa ndi masabata 4-5,
Mphumu ya bronchial - mankhwalawa amagwiritsidwa ntchito popanga zovuta ndi bronchodilators. Amamuika kamodzi pa tsiku kwa masabata atatu,
Asthenic syndrome - tikulimbikitsidwa kumwa madzi a 5 ml. 5 pa tsiku. Kutalika kwa mankhwalawa ndi masiku 14,
Ndi cardialgia, yomwe ikupanga maziko a sitormonal myocardial dystrophy Mildronate - malangizo ogwiritsira ntchito amalimbikitsa kutenga 250 mg kawiri patsiku kwa masiku 12.,
Khola angina pectoris - piritsi limodzi la 250 mg. kapena 5 ml. manyowa katatu patsiku. Tengani molingana ndi chiwembuchi muyenera masiku 3-4. Pambuyo pa izi, Mlingo ndi kuchuluka kwa milingo imasungidwa, koma mankhwalawa amayenera kumwa kamodzi kokha pa sabata. Kutalika kwa mankhwalawa kumasiyana kuyambira miyezi 1 mpaka 1.5,
Angina pectoris wosakhazikika komanso kulowetsedwa kwa myocardial. 0.5-1 g kudzera m`mitsempha, kamodzi patsiku, pambuyo pake wodwalayo mankhwala mankhwala mkati 0,25 ga 2 pa tsiku kwa masiku 3-4,
Ndi kuchuluka kwa nkhawa kapena kutaya mtima, tengani piritsi limodzi la Mildronate 250 mg., Mpaka 4 pa tsiku kwa milungu iwiri. Maphunziro achiwiri sangatengedwe pasanathe milungu iwiri,
Pankhani ya matenda a mtima, Mildronate amasonyezedwa ngati gawo la zovuta mankhwala, mpaka katatu pa tsiku kwa 0,5-1 g. Chithandizo nthawi zambiri chimachitika kuyambira mwezi umodzi mpaka milungu 6,
Odwala omwe ali ndi vuto lalikulu la mtima amawonjezeranso mankhwala othamangitsa mtima glycosides (strophanthin, korglikon, celanide) ndi okodzetsa,
Gawo lazovuta la cerebrovascular pathology. 5 ml aliyense. 10% yothetsera kamodzi patsiku mtsempha kwa masiku 10, pambuyo pake mankhwala amaperekedwa kwa wodwala mkati 0,5 g patsiku. Njira ya mankhwala ndi milungu 2-3.

Mildronate akuwonetsedwa kuti agwiritse ntchito m'mawa ndipo osapitirira 17:00 pamene amatengedwa kangapo patsiku chifukwa chotheka kukhala ndi chidwi chosangalatsa. Akuluakulu 15 mpaka 20 mg. pa kilogalamu kulemera 1 nthawi patsiku, makamaka mphindi 30 musanaphunzire.

Mapiritsi a Mildronate: malangizo ogwiritsira ntchito ndi mlingo

Mapiritsi a Mildronate ali ndi gawo lalikulu. Mankhwalawa amagwira ntchito mochiza matenda ambiri. Malangizo a mankhwalawa akuwonetsa kuti mankhwalawa amapezeka panjira yothetsera jakisoni, komanso mapiritsi a pakamwa.

Mapiritsi ayenera kuti aledzera kwathunthu, saloledwa kutafuna kapena kupera. Sizoletsedwa kutsanulira mapiritsi a Mildronate kuchokera m'mbale. Zizindikiro ntchito matenda a mtima ndi mitsempha ya magazi - mankhwala mu mawonekedwe a mapiritsi ndi makapisozi. Mlingo wovomerezeka tsiku lililonse sapitilira 1000 mg. Mutha kugawa muyeso wofunikira wa mankhwalawa mu 2 application. Njira zochizira odwala ndi Mildronate monga mapiritsi zimatha pafupifupi masiku 30.

Mankhwalawa amatha kugwiritsidwa ntchito ngati cardialgia, yomwe imayamba chifukwa cha kusokonekera kwa mahomoni. Pankhaniyi, ndikofunikira kugwiritsa ntchito mankhwalawa kamodzi patsiku ngati mlingo wa mankhwalawa ndi 500 mg. Ngati mapiritsi ali ndi mlingo wa 250 mg., Ndiye muyenera kumwa mankhwalawa 2 pa tsiku.

Zomwe zimachitika pomwe ma pathologies a pachimake amisamba amachotsedwa, wodwalayo amapatsidwa Mildronate mu Mlingo wa tsiku lililonse wa 500-1000 mg. Amamwa mankhwalawa kamodzi patsiku, kapena amagawa Mlingo watsiku ndi tsiku muyezo zingapo.

Odwala omwe amasintha kwambiri m'magazi kupita ku ubongo amalimbikitsidwa kugwiritsa ntchito mankhwalawa 500 mg. patsiku. Kutalika kwa Inde mankhwala ambiri masiku 40. Dokotala yemwe akupezekapo akhoza kupereka njira yachiwiri yothandizira odwala. Imachitika zosaposa katatu pachaka.

Kwa odwala omwe ali ndi matenda am'mitsempha, Mildronate - malangizo ogwiritsira ntchito amalimbikitsa kusankha kawiri pa tsiku. Ndi nkhawa yamaganizidwe ndi thupi, mankhwalawa nthawi zambiri amapatsidwa mlingo wa 1000 mg. Mlingo wa tsiku ndi tsiku uyenera kugawidwa pamagulu osiyanasiyana. Kutalika kwa chithandizo ndi Mildronate ndi pafupifupi masabata atatu. Pakatha milungu itatu, maphunzirowo akhoza kubwerezedwanso.

Ochita masewera amathanso kugwiritsa ntchito mankhwalawa isanakwane maphunziro. Njira ya mankhwala pokonzekera mpikisano imatha milungu iwiri. Pa mpikisano utha kugwiritsidwa ntchito osaposa masiku 15.

Mildronate jakisoni: malangizo ogwiritsira ntchito

Jekeseni amachitika kudzera m'mitsempha, parabulbularly kapena kudzera m'mitsempha. Mwanjira yoyamba, mankhwalawa amapakidwa m'mitsempha, motero imalowa m'magazi. Ndi jakisoni wa mu mnofu, yankho limalowa mu makulidwe amisempha, kenako ndikufalikira kwa maselo.

Jakisoni wa parabulbar akuphatikizira kuyamwa kwa mankhwalawa m'mizempha ya maso. Njira yothetsera mankhwalawa imapezeka ma ampoules okhala ndi 100 ml. Ayenera kutsegulidwa nthawi yomweyo jakisoni wa Mildronate asanaperekedwe. Ngati ampoule ndi yankho adatsegulidwa pasadakhale, simungathe kugwiritsa ntchito: mankhwalawa ayenera kutayidwa.

Asanatsegule mankhwalawa, yankho lake liyenera kupendedwa mosamala. Onetsetsani kuti mulibe matope kapena malo. Ngati alipo, ndizosatheka kugwiritsa ntchito mankhwalawa pochizira. Gwiritsani ntchito jakisoni kokha njira yabwino, yomveka.

Jakisoni wamkati amatha kuchitika kunyumba, koma jakisoni wamkati ndi parabulbar ukhoza kuchitika kuchipatala. Ayenera kuchitidwa ndi namwino wodziwa ntchito yake.

Mankhwala Mildronate - malangizo, ntchito, zikutsalira jakisoni:

Mildronate - malangizo ogwiritsa ntchito jakisoni amaperekedwa okonzeka kugwiritsidwa ntchito. Mothandizidwa, mankhwalawa amaperekedwa mosiyana ndi mankhwala ena. Mildronate sayenera kuchepetsedwa ndi sodium solution.

Ndi jakisoni wa mu mnofu wa yankho, wothandizira jakisoni nthawi zambiri amakhumudwitsa kupweteka. Momwe zimachitika kuti thupi siligwirizana, kukwiya kwa pakhungu kumachitika. Chifukwa chake, Mildronate nthawi zambiri amabayidwa mwachindunji mu mtsempha. Jakisoni wa Mildronate angagwiritsidwe ntchito pang'onopang'ono wolimba wa angina pectoris, kugunda kwamtima, matenda a mtima ndi ocular fundus.

Kwa odwala omwe ali ndi mtima wamitsempha ya fundus, mankhwalawa amathandizidwa ndi retrobulbarly kapena subconjunctively mu 0,5 ml. kwa masiku 10
Odwala omwe ali ndi vuto la kufalikira kwa ubongo mu mawonekedwe osakhazikika amawonetsedwa jakisoni wa Mildronate katatu patsiku mlingo wa 500 mg. (mulingo woyenera - musanadye chakudya chamadzulo). Kutalika kwa njira ya achire ndi kuyambira 2 mpaka 3 milungu,
Kwa odwala omwe ali ndi coronary syndrome, mankhwalawa amalowetsedwa m'mitsempha mu jet pa 500-1000 mg. Kamodzi patsiku. Zitatha izi, mankhwala akupitiliza kumwa mapiritsi kapena makapisozi,
Odwala omwe ali ndi ngozi ya cerebrovascular mu siteji ya pachimake, yankho limalowetsedwa mu mtsempha 1 nthawi imodzi patsiku la 500 mg. Kutalika kwa njira ya achire ndi masiku 10. Mankhwala ena amaperekedwa pogwiritsa ntchito mitundu ya pakamwa.
Mu coronary syndrome, mankhwalawa amaperekedwa kudzera mu mtsempha wa magazi. Mankhwalawa amagwiritsidwa ntchito 1 nthawi patsiku. Mildronate imayendetsedwa mumtsinje wofanana, mlingo womwe umalimbikitsa sioposa 1000 mg. Pambuyo pa chithandizo cha jakisoni, Mankhwala a Mildronate ayenera kupitilizidwa. Wodwalayo amatenga mankhwalawo ngati mapiritsi kapena mapiritsi,
Ngati pali kuphwanya magazi kwa maselo aubongo mwa odwala omwe ali ndi vuto lofooka la matendawa, yankho liyenera kuperekedwa kudzera m'mitsempha. Gwiritsani ntchito Mildronate - malangizo ogwiritsa ntchito nthawi 1 patsiku. Mlingo wa mankhwalawa ndi 500 mg. Mankhwala ena amachitika pogwiritsa ntchito mapiritsi,
Ngati wodwala akuvutika kwambiri chifukwa cha kufalikira kwa matenda a chithokomiro, Mildronate amayenera kuthandizidwa ndi intramuscularly. Mankhwala amagwiritsidwa ntchito pafupifupi kawiri pa tsiku pa mlingo wa 500 mg. Ndikofunika kugwiritsa ntchito mankhwalawa m'mawa. Kutalika kwa mankhwalawa nthawi zambiri pamasabata atatu,
Ngati wodwala wasintha mu minofu, mankhwalawa amayenera kuperekedwa kupitirira maso. Kutalika kwa mankhwala osachepera masiku khumi. Mankhwala motere amagwiritsidwa ntchito pa mlingo wa 0,5 ml.

Mildronate: zomwe zimayikidwa ndi zomwe zimathandiza mapiritsi ndi jakisoni kuchokera

Mutatha kugwiritsa ntchito Mildronate, mutha kupirira kupanikizika kwambiri kwa thupi ndikuchira msanga. Chifukwa cha izi, mankhwalawa amagwiritsidwa ntchito pokonzanso magazi kupita ku ubongo ndikuchiza matenda osiyanasiyana a mtima, komanso kuwonjezera mphamvu,
Pankhani ya ischemic cerebrovascular ajali, Mildronate amagwiritsidwa ntchito kukonza magazi poyang'ana ischemia, yomwe imathandizira kugawa magazi,
The yogwira mankhwala Mildronate bwino kagayidwe, amathandiza kuchotsa poizoni zofunikira m'maselo, ali ndi mphamvu tonic ndipo amateteza maselo kuwonongeka.
Kulephera kwa mtima, Mildronate malinga ndi malangizo amawonjezera kukhudzika kwa mtima, kumachepetsa pafupipafupi kugunda kwa angina, pomwe kumakulitsa kulolerana,
Komanso, malinga ndi ndemanga, Mildronate ndiwothandiza pakusokonekera kwa mitsempha ndi matenda amkati komanso ndi fundus pathology,
Meldonium imathandizira kuchepetsa kuchuluka kwa mafuta a carnitine aulere, kumalepheretsa mayendedwe amafuta amtali a ma cell kudzera mumitsempha yama cell, imalepheretsa kuchuluka kwa mafuta omwe sanapangidwe ndi oxidized acid muma cell, omwe ndi acylcarnitine ndi acylcoenzyme,
Mu minofu ya ischemic, imabwezeretsa malire pakati pa kayendedwe ka okosijeni ndi kukwera kwake ndi maselo, imalepheretsa kuphwanya kwa kayendetsedwe ka adenosine triphosphate, kuyambitsa nthawi yomweyo glycolysis, yomwe imatuluka popanda kugwiritsa ntchito mpweya. Zotsatira zakuchepa kwa kuchuluka kwa carnitine ndimapangidwe opanga vasodilator γ-butyrobetaine,
Zochita za yogwira mankhwala zimalepheretsa ntchito ya enzymatic ya γ-butyrobetaine hydroxylase, womwe ndi womaliza kutengera mphamvu ya kapangidwe ka L-Carnitine,
Mutatha kumwa pa mapiritsi a os oser, Mildronate - malangizo ogwiritsira ntchito, meldonium yomwe ili mmenemo imalowa mwachangu m'mimba. Mankhwala amadziwika ndi mtundu wapamwamba kwambiri wa bioavailability. Zotsirizazo ndi pafupifupi 78%,
Kuchulukana kwa meldonium m'madzi a m'magazi kumafikira pazomwe zimachitika pakatha ola limodzi kapena awiri. Mthupi, meldonium imapangidwira ku zinthu zopanda poizoni - shuga, supplement, 3-hydroxypropionic acid,
Kupereka kwa metabolites kumachitika ndi impso. Hafu ya moyo (T½), kutengera mawonekedwe a chinthu china komanso mlingo womwe umatenge, ukhoza kukhala maola atatu mpaka 6,
Kukonzekera kosavomerezeka kumadziwika ndi 100% bioavailability. Kuchulukana kwa meldonium m'madzi a m'magazi kumafikira pazofunikira zake pambuyo pake pa mankhwala.
Zotsatira za kagayidwe ka Meldonium ndikupanga ma metabolites osakhala ndi poizoni (glucose ,ced, 3-hydroxypropionic acid), omwe amachotsedwa m'thupi ndi impso.

Zotsatira zoyipa mukamagwiritsa ntchito mankhwalawa

Zotsatira zoyipa chifukwa chogwiritsa ntchito Mildronate zimachitika nthawi zambiri. Monga lamulo, amafotokozedwa ngati:

Kusintha kwa kuthamanga kwa magazi,
Tachycardia,
Psychomotor overexcation,
Zofooka zambiri
Beling, flatulence ndi zizindikiro zina za dyspepsia,
Kuchuluka kwadzaoneni
Zizindikiro zam'mimba, zowonetsedwa ndi kupindika, kusanza, kusanza, kutentha kwam'mimba, kumverera kwathunthu kwam'mimba ngakhale mutadya pang'ono,
Kuchuluka kwamphamvu kwa ma eosinophils m'magazi,
Komanso, Mildronate - malangizo omwe angagwiritse ntchito malinga ndi ndemanga angayambitse kusintha kwa thupi lanu mu mawonekedwe a edema, totupa, redness kapena kuyabwa.

Ndi kulekerera bwino, muyenera kudziwitsa dokotala yemwe akupezekapo za izi kuti musinthe njira yomwe mwasankhayo kapena m'malo mwamankhwala.

Chenjezo liyenera kuchitika mukamagwiritsa ntchito mankhwala ena a antianginal and antihypertensive, komanso glycosides a mtima, popeza Mildronate amawonjezera zomwe amachita. Ndi munthawi yomweyo kugwiritsa ntchito antihypertensive mankhwala, nifedipine, nitroglycerin, zotumphukira vasodilators ndi alpha-blockers, tachycardia wofatsa komanso ochepa hypotension angachitike ndi Mildronate.

Mildronate imatha kutengedwa ndi anticoagulants ndi antiplatelet othandizira, komanso mankhwala a diuretic komanso antiarrhythmic. Security Mildronate imathandizidwa ndi malipoti osinthidwa nthawi ndi nthawi ndi zotsatira za mayeso azachipatala osindikizidwa.

Latvia itagwirizana ndi European Union, chofunikira pakuwongolera chinali kupezeka kwa dongosolo la Pharmacovigilance, lomwe limayang'anira ndikuwunika ntchito zamankhwala.

Chiyambireni kuwunikira (kuyambira pa Marichi 21, 2006), JSC "Grindeks" ilandila malipoti 47 (mwachangu) onena za zinthu zomwe zili ndi meldonium. Panalibe malipoti a zachipatala zomwe zidayamba kugwiritsa ntchito mankhwala osokoneza bongo komanso kugwiritsa ntchito bongo. Panalibe malipoti azokhumudwitsa kapena zosintha kuchokera kwa othamanga.

Zizindikiro zogwiritsira ntchito Mildronate

Zisonyezero zogwiritsira ntchito Mildronate (mitundu yonse ya mankhwala):

Kuchepetsa ntchito
Kuchulukitsa kwakuthupi (kuphatikiza pamasewera),
COPD
Matenda a mtima, kuphatikizapo ischemic,
Vitreous hemorrhage m'maso (hemophthalmus),
Matenda a m'mitsempha
IHD (kuphatikiza mankhwala ena ndi njira zochiritsira),
Cardialgia (kupweteka kumanzere kwa chifuwa) chifukwa cha dishormonal myocardiopathy,
Stroko
Thrombosis ndi kupindika kwa chapakati retina mtsempha kapena nthambi zake,
Dyscirculatory encephalopathy,
Nthawi yogwirira ntchito (kufulumizitsa kuchira kwamthupi),
Matenda opatsirana
Mphumu ya bronchial,
Retinal hemorrhage,
Matenda amisala omwe amayamba chifukwa cha mowa.

Kutetezedwa kwathunthu kwa Mildronate mu chithandizo cha amayi apakati sikunatsimikizidwe. Pofuna kupewa zovuta za mankhwalawa pathunthu komanso thanzi la mwana wosabadwa, sikofunikira kugwiritsa ntchito Mildronate panthawi ya bere. Zomwe mankhwalawa amathandizira tidazindikira, komabe, pa nthawi ya pakati, ndiyofunika kupewa mankhwalawa.

Sizikudziwika ngati meldonium ilipo mu mkaka wa m'mawere mwa akazi. Chifukwa chake, pochita ndi Mildronate, madokotala amalangizidwa kuyimitsa kuyamwitsa kwa amayi. Mildronate amalumikizana momasuka ndi mankhwala osiyanasiyana, samatsutsana nawo.

Nthawi zambiri amagwiritsidwa ntchito pamavuto a kugona Mildronate. Chifukwa chiyani mankhwalawa amalembedwa pamilandu yotere? Pofuna kuthana ndi kusowa tulo kapena maloto owoneka bwino, olusa, wokhala ndi chizungulire, phokoso m'makutu ndi m'mutu, ndikomoka pafupipafupi.

Mildronate - malangizo ogwiritsidwira ntchito amatha kuonjezera kukondoweza kwa anthu, chifukwa chake, mutagwiritsa ntchito mankhwalawa, kupsinjika kwa thupi ndi malingaliro ndikosavuta. Mildronate nthawi zambiri amagwiritsidwa ntchito ndi othamanga. Kupatula apo, imakonza thanzi la mtima, imathandizira kuchepetsa kutopa, chifukwa chake imakulitsa kulimbitsa thupi. Mildronate amathandizira kuti maselo amthupi azitha kuchira komanso kuthamanga.

Contraindication

Malinga ndi malangizo ogwiritsira ntchito, Mildronate amalephera kugwiritsidwa ntchito mwa ana osakwana zaka 18, ndi hypersensitivity mankhwala.

Mapiritsi ndi jakisoni Mildronate - malangizo ogwiritsa ntchito amalangiza kuti asatenge: zotupa za intracranial, kusokonezeka kwapadera, kusazindikira kwa mankhwalawo, komwe matupi awo amatha kuyambitsa.

Kafukufuku wodalirika pakugwiritsa ntchito Mildronate pa nthawi ya pakati komanso mkaka wa m`mawere sanachitike, chifukwa chomwe mankhwalawa sakuvomerezeka kuti agwiritse ntchito nthawi imeneyi. Chenjezo: Matenda a chiwindi ndi impso.

Malangizowo amakumbukira kuti kugwiritsa ntchito mankhwalawa ndi mowa sikungaphatikizidwe, makamaka ngati kumagwiritsidwa ntchito pochiza matenda amtima. Mankhwala amagulitsidwa m'mafakisoni pokhapokha ngati mwalandira mankhwala.

Mtengo wa Mildronate m'masitolo ogulitsa, kuchuluka kwa mankhwalawo

Mtengo wa mankhwalawo umatengera mtundu wa kumasulidwa. Mtengo wapakati wonyamula makapisozi ndi 250 mg. - kuchokera ku 250 mpaka 300 ma ruble, mapiritsi a 500 mg. - kuchokera 559 mpaka 655 ma ruble., jekeseni wa makonzedwe amkati - ma ruble a 320-380., Mildronate Gx 500 mg. - 715-720 rubles.

Makapu a Mildronate 250 mg. No. 40 (Latvia) 297.00 rub.,
Makapu a Mildronate 500 mg. No. 60 (Latvia) 646.00 rub.,
Mildronate jakisoni / ma ampoules 10% 5 ml. No. 10 (Lithuania) 401.00 rub.,
Mildronate jakisoni / ma ampoules 10% 5 ml. No.20 (Lithuania) 751.00 rub.

Mildronate: zotchipa komanso zotha kusintha

Zofananira zonse zogwira ntchito:

Midolat
Meldonia dihydrate,
Idrinol
Medatern
Melfort,
Meldonius Eskom
Meldonium
Vasomag,
Trimethylhydrazinium propionate dihydrate,
3- (2,2,2-Trimethylhydrazinium) propionate dihydrate,
Cardionate

M'mafakitala, mtengo wa makapisozi umayamba pa ma ruble 300 pama mapiritsi 40 a 250 mg aliyense. Kwa jakisoni 10 a Mildronate 10% mu ampoules a 5 ml. muyenera kulipira ma ruble 400.

Kugwiritsa ntchito kwa Mildronate pa mimba ndi mkaka wa m`mawere

Mildronate - malangizo ntchito ntchito poletsa pathupi. Izi ndichifukwa choti chitetezo cha mankhwalawo sichingatsimikiziridwe mokwanira. Zida zomwe zimapanga kulowa mu zotchinga, chifukwa chake pogwiritsa ntchito mankhwalawa, kuyamwitsa mwana kuyenera kuyimitsidwa.

Sizikudziwika ngati meldonium ikhoza kuchotsedwa mkaka wa amayi oyamwitsa. Chifukwa chake, ngati mayi akuwonetsedwa chithandizo ndi Mildronate, munthawi yonse ya chithandizo akuyenera kusiya kuyamwitsa.

Mildronate ndi mowa: kuyanjana, kungatengedwe palimodzi

Monga ma analogu ena, Mildronate (ndemanga, malangizo amatsimikizira izi) amawonetsa zotsatira zabwino mothandizidwa ndi anthu omwe amamwa zakumwa zoledzeretsa.

Ndi matenda a kutulutsa, Mildronate amagwiritsidwa ntchito kanayi pa tsiku. Mulingo wambiri watsiku ndi tsiku umachulukana kawiri kawiri pazochitika zina: umafika pa 2 ga nthawi yonse ya sabata limodzi ndi theka.

Ndi chidakwa cha chidakwa komanso kuledzera kwambiri kwa thupi, Mildronate angagwiritsidwe ntchito ngati jakisoni. Pogulitsa, mankhwalawa amaperekedwa okonzekera kugwiritsidwa ntchito. Akayambitsidwa m'thupi, Mildronate ndi mankhwala ena sayenera kusakanikirana. Sitikulimbikitsidwa kugwiritsa ntchito yankho la sodium pophera mankhwalawa.

Kuyambitsa mtsempha nthawi zambiri kumalimbikitsidwa pamatenda a coronary, ndipo mankhwalawa amaperekedwa kamodzi pa tsiku kuchuluka kwa 1 gm. Mankhwala othandizira a Mildronate amachotsedwa m'thupi pakatha maola 12, chifukwa chake, patadutsa nthawi imeneyi, chiopsezo chogwiritsa ntchito mankhwala ndi chinthu china chogwira ntchito chimakhala chochepa kwambiri kapena chosakhalapo .

Zonse mwa zonse kumwa mowa pa mankhwala ndi Mildronate sikuletsedwaKomabe, ngati mankhwalawa agwiritsidwa ntchito pochiza matenda amkati kapena ngati magazi a m'magazi atasokonekera, wodwalayo amalangizidwanso kuti amwe mowa.

Kusagwirizana bwino kwa Mildronate ndi mowa kumachitika chifukwa cha chiwopsezo chowonjezereka cha zovuta zosiyanasiyana komanso kuthekera kobwereranso kwa matendawa. Odwala omwe amamwa mowa chifukwa chomwa mowa nthawi zonse, mankhwalawa amayenera kugwiritsidwa ntchito kanayi pa tsiku. Mlingo woyenera sayenera kupitirira 2000 mg. Kutalika kwa chithandizo chamankhwala ndi pafupifupi sabata limodzi ndi theka.

Cardionate kapena Mildronate - zomwe zili bwino

Cardionate ndi Mildronate ndi mankhwala ofanana. Maziko ake ndi chinthu chimodzi chomwe chimagwira, motero onse omwe ali ndi kachitidwe kofananira. Kusiyanitsa kokhako ndikuti, mosiyana ndi Mildronate, Cardionate amangopezeka mwa mawonekedwe a 250 mg makapisozi. ndi 500 mg / 5 ml jakisoni njira.

Kugwiritsira ntchito modekha m'masewera: mawonekedwe ogwiritsa ntchito

Mildronate - malangizo ogwiritsira ntchito amadziwika pakati pa othamanga akatswiri pazinthu zawo kuti athandize thupi kuyambiranso kuphunzitsidwa bwino. Meldonium imathandizira kuti maselo a oxygen adalitsidwe ndi okosijeni, ndikuchotsa zinthu zowonongeka. Kuphatikiza apo, imapatsa mphamvu maselo. Wothamanga akamachira msanga, amayambanso maphunziro ena m'mbuyomu, kenako zimamuyendera bwino.

Zizindikiro zakugwiritsira ntchito mankhwalawa kwa othamanga amakhala ndi nthawi yophunzira kwambiri komanso pafupipafupi, ndipo alibe nthawi yoti achire pakati pawo. Malangizo ogwiritsira ntchito ndi iye ali motere: makapisozi kapena mapiritsi amayenera kukhala okwanira mpaka 1 g ya zinthu patsiku, atengereni mphindi 30 asanaphunzitsidwe.

Jakisoni wamkati ndiwothandiza kwambiri, mlingo wa tsiku lililonse wa othamanga ndi 5-10 ml. Njira yovomerezedwa sayenera kupitirira milungu isanu ndi umodzi. Mankhwala siosokoneza bongo.Kumbukirani kuti kugwiritsa ntchito mankhwala a jakisoni kapena mapiritsi amkamwa, mapiritsi, sichidzalowa m'malo mwa mpikisano wokhala ndi zakudya zopatsa thanzi zama protein ndi mapuloteni.

Ngati mutakhala pachakudya chocheperako, imwani Mildronate - malangizo omwe angagwiritsidwe ntchito akuti alibe pake, chifukwa sasokoneza thupi lotopa. Kuthekera kwa mankhwala poletsa mafuta acids kuti asalowe m'maselo a thupi kumathandizira kukwaniritsa mphamvu ya kuchepetsa thupi pamasewera olimbitsa thupi.

Mawonekedwe:

Amachepetsa kutopa
Mikhalidwe ya ischemia, imabwezeretsa bwino momwe magwiridwe antchito amtundu wa oxygen ndikuperewera kwake m'maselo, kumalepheretsa kuphwanya kayendedwe ka ATP,
Amasintha zakudya zamafuta
Imaletsa kudzikundikira kwamaselo amitundu yamafuta acid,
Kuteteza mtima ndi kuwonjezera kukhudzika mtima,
Zimawonjezera luso la maphunziro,
Imayendetsa glycolysis, yomwe imatuluka popanda kugwiritsa ntchito mpweya.

Mildronate amaletsa mafuta acids kuti asalowe mu cell ndipo motero amalepheretsa kuchuluka kwa mafuta m'chiwindi. Kuphatikiza apo, kuwotcha shuga kwambiri, thupi limagwiritsa ntchito zinthu zochulukirapo, zomwe zimangokhala mafuta, pa molekyu iliyonse ya adenosine triphosphate yopangidwa (kutanthauza kupanga mphamvu).

Mexicoidol ndi Mildronate (meldonium) - kuwunika kwamavidiyo

Meldonius sanali m'gulu loyendetsa zigawenga mpaka Januware 1, 2016, zomwe zidaloleza kuti azigwiritsidwa ntchito movomerezeka mwamasewera onse. Komabe, ataletsa kugwiritsa ntchito ndalama ndi World Anti-Doping Agency (WADA) koyambirira kwa chaka cha 2016, osewera ambiri, makamaka ochokera ku Russia ndi mayiko a CIS wakale, adapezeka kuti ali ndi mlandu wogwiritsa ntchito mankhwalawa. Mildronate adakhalanso mutu wankhonya waukulu pomwe Maria Sharapova adazindikira kugwiritsa ntchito dope ili pa Marichi 7, 2016.

Ndemanga za Grindeks Mildronat

Malinga ndi madotolo, othamanga komanso odwala omwe ali ndi mavuto a mtima, MILDRONATE ali ndi mphamvu yokhala ndi tonic. Malinga ndi akatswiri a mtima, kumwa mankhwalawa kumachepetsa mwayi wachiwiri wolimbana ndi matenda a mtima. Kuunika kwa chida ichi kukuwonetsa kuti ndikofunikira kwa iwo omwe ntchito zawo zimagwirizanitsidwa kwambiri ndi katundu wambiri.

Komanso, mankhwalawa amafunikira ululu wamtima, kuyaka m'dera la minofu yamtima. Komanso, pakubwezeretsa kwakumwa pambuyo pakumwa kwa nthawi yayitali, Mildronate amalembedwa - malangizo ogwiritsira ntchito. Mowa, womwe umagwirizana ndi zero, umachotsedwa mwachangu mthupi ndi chithandizo cha mtundu uwu. Pa kachitidwe ka 5-point, kuchuluka kwa mankhwala omwe apatsidwa ndi 4,8 mpaka 5.

Kumbukirani kuti kudzipereka nokha ndi owopsa thanzi lanu! Onetsetsani kuti mwawonana ndi dokotala! Zomwe zili patsamba lino zimangoperekedwa pazophunzitsira zodziwika bwino ndipo sizitanthauza chidziwitso ndi kulondola kwa zamankhwala, sizitsogolera kuchitapo kanthu.

MILDRONAT - nkhani zenizeni ndi malingaliro okhudzana ndi mankhwalawa:

Sindinathe kupirira chilimwe, chifukwa ndikangotentha, ndimayamba kutopa kwambiri ndikukhala oopsa, osweka, mtima wanga umagunda mosalekeza, ngati kuti ndikugwira ntchito ndi mphamvu zanga zonse. Chaka chatha, adazindikira "kulephera kwa mtima" ndipo adalangiza Mildronate - malangizo ogwiritsira ntchito. Tsopano ndakonzeka kum'pangira chipilala! Chenjezo loyamba - musamwe mankhwalawa madzulo, sizingatheke kugona. Zimakhala ngati chidebe cha khofi kumwa - simungakhale chete, koma izi ndizothandiza masanawa. Momwe mumamwa kwambiri - ndipo ndimamwa 1 mg. zotchulidwa - izi ndizomwe zikuwoneka kwambiri, kotero zinali zovuta kuti ndikhale kuntchito, ndimafuna kuti ndiyimirire ndikuthamanga, thupi langa linali kuphulika ndi mphamvu zochulukirapo .Dziwani kuti upangiri woyamba ndiwakuti ndibwino kumwa mankhwalawa panthawi yayikulu patchuthi, mukasafunikira kukhala chete ndikuti yang'anani kompyuta kwa maola ambiri. Wachiwiri. M'masabata angapo chabe, sizothandiza kuti zidziwike - ndi ine za mtima. Poyamba, momwe wopangira magetsi amagwirira ntchito, tsiku ndi tsiku, ndimamva kuti mtima wanga ukugunda osati zolimba kwambiri kuyambira kale, komanso kutopa kwanga kumachepa,
Ndidatenga Mildronate zisanakhale zazikulu. Dokotala wake wa ma neuropathologist adandisankha zaka zingapo zapitazo - adatopa pakukonzekera gawoli, adalibe mphamvu yodziwira zambiri. Pazonse, mankhwalawa si a nootropic, koma kuchokera ku vuto la kuchepa kwake amathandizadi .. Chofunikira ndikuyamba kumwa mankhwalawa msanga, ngakhale pokonzekera kwambiri gawolo kuyamba - masiku 3-4 ndibwino masiku. Kenako mankhwalawo amakhala ndi nthawi yoti atuluke mu mphamvu zake zonse ndipo zotsatira zake zidzakhala zosangalatsa. Zotsatira zake ndikuti mumangokhala wamphamvu kwambiri - simutopa thupi kapena m'maganizo, usiku ogona kukonzekera mayeso simakupangirani masamba, tsiku lotsatira ndinu osangalala komanso mwatsopano. Kuchita bwino kumachulukitsa, nditha kuchita zonse mwachidule usiku pitani ndikumakumbukira zambiri momwe mungathere sabata limodzi. Chilichonse chimakumbukiridwa nthawi yomweyo poyesa koyamba, ndizosavuta, palibe chisokonezo konse, kotero gawo lirilonse ndi Mildronate limatha ndi zolembera zabwino zokha,
Zaka zingapo zapitazo ndidapezeka ndi matenda oopsa komanso VVD, i.e. michere-mtima dystonia. Kupanikizika kunali kosachepera, pafupifupi 90/60, ndikufika 80/45. Posachedwa, ndimakhala bwino komanso wopanda nkhawa pa 100 / 70-80 yokha. Ngati kupanikizika kuli pamwambapa / pansi pa mulingo wosonyezedwa, ndinamva kuwawa kwambiri. Mphamvu zopanda mphamvu, kugona, zinafikira pakukomoka. Izi, zachidziwikire, zidasokoneza kwambiri moyo wabwinobwino. Ndinapita kuchipatala. Adachita kafukufuku wathunthu, kusanthula, ndi zina zambiri. Dokotala adapereka chithandizo, woyamba jekeseni wa Mildronate, kenako milungu inanso iwiri kuti amwe mankhwalawa. Dotolo adalangiza kuti amwe mankhwalawa kawiri pachaka, m'dzinja ndi masika. Ndikumva kuti zimayamba kukhala zovuta kapena zoyipa - ndimamwa iwo.Chofunika kwambiri - Mildronate uyu - malangizo ogwiritsira ntchito siowopsa. Amalandira kwa othamanga ndi ophunzira mkati mwa gawoli. Imateteza komanso kusilira maselo amthupi, ndikupereka mpweya wabwino kwa iwo ndikuthandizira kuthetsa kuchuluka kwa poizoni. Mtengo wa Mildronate ndiwotsika ndipo ndikokwanira osati kamodzi kokha,
Mutu ukakana kuganiza, umathandiza kwambiri komanso nthawi zonse. Nthawi ndi nthawi ndimatopa kuntchito - ndimakhala kuti sindikugona mokwanira, chifukwa ndimayamba kusokoneza chilichonse ndipo mutu wanga umangosokonekera. Zikatero, ndimagula Mildronate mu mawonekedwe a jakisoni - mwanjira iyi, mankhwalawa amamwa bwino, ndipo zotsatira zake zimawoneka mwachangu. Zachidziwikire, sizikuchokera pakubaya koyamba kuti mumazindikira, koma zotsatira zake zimakula pang'onopang'ono, ndipo mkati mwa chithandizo mutu umayamba kumveka, mphamvu zikuwonjezeka. Chida chodabwitsa ndichakuti mutha kugonanso pang'ono, koma kukhala ndi nthawi yochita zochulukirapo, kumawonjezera zokolola za ntchitoyo, chifukwa kuwerengera kumeneko zomwe ndimakhala nawo masiku angapo, tsopano nditha kuzichita usiku umodzi popanda cholakwika chimodzi. Mukumva kuti muli ndi mphamvu, kusangalala, ndulu zimasowa paliponse. Chofunikira kwambiri ndikuti zotsatira zomwe zimachitika mukangotaya sizimatha, Mildronat akuwoneka kuti akuyamba njira zina mthupi, chifukwa cha zomwe ndimalima kwa miyezi ingapo, ngati kavalo, osatopa kwathunthu. Ngati nthawi ndi nthawi maphunziro a Chithandizo akuchitika, mutha kungotembenuzira mapiri
Kalekale, pamene ndimayesera kuthamanga mtunda wautali kale pakati pa njirayo, ndinayamba kumva kupweteka kwambiri mu hypochondrium yamanzere, zimandivuta kupuma. Anati izi zachitika chifukwa chokhala moyo wopanda ulesi komanso ulesi. Anapezeka kuti ndi angina pectoris. Wodwala zamtima sankaganiza zambiri, adalembera Mildronate - malangizo a kumwa makapu anayi patsiku kwa mwezi umodzi. Ndinafunika kunyamula mapaketi akuluakulu a mankhwalawo - osati otsika mtengo, mtengo uliwonse wa Mildronate unali ma ruble 750. Ponena za mtima, sindinadziwenso yomweyo, koma zotsatira zabwino za "mphamvu" zidawonekera mwachangu - ndinakondwera ndi mutu womveka komanso woganiza bwino patatha milungu iwiri. angina pectoris amachitikanso pafupipafupi, koma osati nthawi yomweyo, ndinazindikira kuti zimapweteka pang'ono, ndipo ululuwu suwakhalapobe ngati kale. Zotsatira zowoneka mwachangu zinali kumapeto kwa chithandizo - inde, mankhwalawo adathandizira, chifukwa pafupipafupi akuukiridwa amachepa kwambiri, dyspnea yanga idasowa.

Monga tikuwonera kuchokera pa kuwunika, malangizo a mapiritsi ndi jakisoni a Mildronate, mankhwalawa adapangidwa kuti apititse patsogolo kayendedwe ka mtima. Mothandizidwa ndi gulu lazangu, mpweya wabwino m'magazi a anthu umakwera. Izi zimachepetsa chiopsezo cha matenda a mtima. Chidacho chimaphatikizidwa pamndandanda wazofunikira zamankhwala.

Amakhulupirira kuti kutenga Mildronate kungakhudze chiwindi, komwe pakapita nthawi kumatha kudwalitsa. Palibe chitsimikiziro chovomerezeka cha izi pakadali pano, kapena kulumikizidwa kulikonse mu ntchito ya chiwindi ndi zochitika zolimbitsa thupi.

Mildronate imalepheretsa kulowa kwa mafuta acids kukhala tiziwalo tating'ono tating'ono, komwe chiwindi chimatetezedwa kuti sichulukane ndi mafuta. M'malo mwake, Mildronate amamuthandiza.

Kuchokera munkhaniyi ya zachipatala tidadziwana ndi mankhwala a Mildronate - malangizo ogwiritsira ntchito omwe adatifotokozera momwe mungagwiritsire ntchito mankhwalawa, zomwe zimathandizira nawo, ndi ziti zomwe zikuwonetsa kugwiritsidwa ntchito, contraindication ndi mavuto.